AI Companies That Raised Over $100M+ | Pt. 3

2 Jan 2026 · 9 min · 4 chapters

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In short

Part 3 of a series profiling top AI companies that raised $100M+ in March 2025, focusing on what industries are getting funded and who is funding them.

Guests

No specific podcast guests are named; hosts Jamie and Bluff discuss the list.

Key claims

OpenAI raised $40B in March, valuing it at $300B (led by SoftBank; also Thrive Capital, Microsoft, Kotu). NextHop AI raised $110M Series A (led by Lightspeed; Kleiner Perkins, Battery Ventures, Emergent Ventures). Ilseco Medicine raised $110M Series E for AI-powered drug discovery (co-led by Value Partners; Pudong Chow Tong Tu). Celestial AI raised $250M Series C (valued $2.5B; led by Fidelity; Tiger Global, BlackRock, Intel CEO Lip Bhutan) and later merged/acquired Marvel for data-center connectivity. Lilia Sciences raised $200M seed for an autonomous “scientific super intelligence” platform using robotics for life/chemical/material sciences.

Notable examples

AI + robotics for chemical mixing and drug discovery; autonomous labs for experiments; data-center connectivity via Celestial AI’s merger.

Written by AI. May contain mistakes. Listen to the episode to check what was said.

Chapters

Tap a time to open that second in VO

AI Companies Raising Funds in March

1:00 to 2:50

Exploring companies that raised over $100 million in March 2025.

“not available in all states or situations.”

OpenAI and its Record-Breaking Raise

2:50 to 6:00

Discussing OpenAI's $40 billion funding round and its implications.

“So another AI infrastructure company, like I said before, that's going to be a huge industry moving forward.”

AI in Drug Discovery and Research

6:00 to 8:40

Exploring various AI companies involved in drug discovery and research.

“Yeah, that whole concept like totally blows my mind.”

Future of AI Infrastructure Companies

8:40 to 9:30

Examining AI infrastructure companies and their significance in the future.

“Well, hey, March had a lot of different companies that raised over$100 million.”
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Transcript

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1:15We're doing this for a couple of different reasons, but we find it's number one, just really interesting to see where the industry is. We do a small profile on each company, try to give you an idea of what they're currently working on, because this gives you a good idea of what industries are receiving funding, how they're receiving funding, who's giving them money. I think this is just, it's a pretty eye-opening, it's a pretty eye-opening series. We love doing it, so we hope you enjoy it. We're going to start with all of the companies that raised over$100 million in March this year. But before we do that, Jamie, why don't you tell them about our AI Hustle School community?

1:49Yeah, if you've ever wanted to learn how to grow your business with AI, get an unfair competitive advantage amongst others, or even just make money on the side using AI, you should definitely check out our school community called AI Hustle. Each week we release bonus content over there, sharing exact strategies with how we are growing our own businesses and making money with AI. So this past week we did one with Jing. He talked about a special way he's making AI podcasts and having it sound natural and not like a robot voice. So there's just tons of different content. We do things about being an AI consultant, making content, marketing, all that kind of stuff.

2:32So if that interests you, you should definitely check it out. You can lock in our price of$19 a month. That's a holiday special. It's normally more money than that, but you can lock that price in forever if you join today. So go check that out. But yeah, let's get into March, starting with number one. uh this one is a very obvious obvious one but open ai raised 40 billion dollars in march which is absolute insanity but uh to be expected yeah i love how the whole list we like go through and we're like this company raised like 105 million this one raised like 200 million oh my gosh open ai 40 billion dollars just in march they've raised so much money it's insane so that valued them at 300 billion um they it was led by soft bank so it's kind of interesting because the bigger these rounds get the bigger the players come in when you have soft bank coming in you know your you know your uh you mean business they also had thrive capital they had microsoft uh they have kotu all of those so they had the big boys they brought out the big guns and 40 billion dollars later we have open ai um who still has not achieved agi but we'll forgive them because their models are you know generally pretty good i guess for sure and that puts their valuation at 300 billion as of march so um pretty pretty insane valuation but like you said they're on top so uh next in march we have next hop ai which is a another ai infrastructure company so um they had they raised a series a round um led by light speed ventures for a 110 million dollar uh raise so So they also included Kleiner Perkins, Battery Ventures, Emergent Ventures, and some others.

4:17So another AI infrastructure company, like I said before, that's going to be a huge industry moving forward. Yep, yep, that's going to be massive. Okay, next up we have Cambridge, Massachusetts-based Ilseco Medicine. They raised$110 million. dollars there's a lot of players that have been in this space this year that i'm really excited about but they're using ai for ai powered um drug discovery they announced this this is their series e so they've been doing this for a little while uh the company's valued at a billion dollars it was co-led by value partners and uh pudong chow tong tu out of um china and so it's it's kind of interesting there is a there's obviously a lot of money to be made in drug discovery what i find is when some of these drug discovery companies are raising money, it's because they've usually made some sort of breakthrough and they want more money and people are interested in investing because they feel like they're getting close to discovering some drugs or they have a breakthrough process for the discovery.

5:21We've seen a lot of interesting players here. This$100 million is interesting. We've seen two different things. One, where a company like this is going to use AI to help them come up with concepts for drugs. Another one where they help them test like a lot of drugs. And then some interesting ones where they actually use robots to mix chemicals that they wouldn't necessarily want humans to do, or maybe they do them faster than humans. The AI comes up with like chemical compound mixture ideas. They have a robot do the actual mixing. They have an AI and analyze it. So there's like some really interesting stuff happening with AI drug discovery.

5:58So this will be an exciting one to keep following in the future. Yeah, that whole concept like totally blows my mind. I was a chemistry minor in college. And so like the whole idea of it, of AI doing drug discoveries is totally crazy. I would love to chat for, you know, an hour with someone in the industry. It's totally super cool. So we got another AI infrastructure company next called Celestial AI. They raised$250 million in their series C round that valued them at$2.5 billion, with a B, on March 11. So this round was led by Fidelity with participation from Tiger Global, BlackRock, and Intel CEO Lip Bhutan, among others.

6:43So another AI infrastructure company. And I will say for those curious, they actually have just completed a merger. So the update on them is that they've merged with a company called Marvel, or I mean, got acquired basically, but it's going to help scale up connectivity for the next generation of data centers. This is kind of where they're specifically focusing on. So this is interesting, right? This is a company that was able to raise a lot of money. They raised $250 million. They were then acquired. Obviously, this is a company that had a massive backers, Tiger, BlackRock, Intel CEO, you know, Fidelity, like all the big banky kind of people were in on this deal.

7:25And so getting acquired is no shocker. And I think that the acquisition probably paid out nicely for their investors. So congratulations to everyone over at Celestial AI. The merger was just announced December 2nd of this year. So they were able to get this deal done to March 11th and by the end of the year get acquired. Yeah. So next on the list, we have Lilia Sciences, which raised $200 million in their seed round as it looks to create science super intelligence platform. So it's kind of a generic idea. I'm not exactly sure what they're going for, but I do know moving forward, having specific use cases for different AI programs will become more and more necessary.

8:06For example, we talked about the medical AI has a very specific skill set and specific data it needs to train on. So I'm guessing it's something along those lines where it's more science focused. Jayden, have you heard anything about this company? yeah i think this is one of those autonomous companies that uh i was telling you about before or we're talking about before so they said we are introducing the world's first scientific super intelligence platform and autonomous labs for life chemical and material sciences to rapidly expand human knowledge and push the limits of whatever their their tagline but basically it's autonomous chemical material sciences so it will have like the robotics uh element to it i think um um where you have like the ai and robots mixing chemicals doing a lot of these uh experiments and figuring stuff out they have a really cool video on their website where they have um like these little i mean it's like machines but it's kind of these robots picking up vials and moving stuff around so it's it's kind of mixing the robotics and the uh and the ai for decision making together to help come up with new drug discovery stuff and and other things in in material sciences.

9:18Very cool. Very cool. Well, hey, March had a lot of different companies that raised over$100 million. We're going to continue that list next time. But in the meantime, we appreciate you listening. Thanks for listening. If you would leave us a rating or review wherever you are listening, we would really appreciate it. It helps us reach more people. And again, check out the AI Hustle School community. If you want to grow your business or make money on the side using AI, we would love to have you be a part of it. Thanks for listening and we'll see you next You know what? It sucks to be bored. But when I get on my phone and play real casino games on spinquest.com, the time flies by.

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From the publisher

Jaeden and Jamie discuss the latest trends in AI funding, focusing on companies that raised over $100 million in March 2025. They highlight significant investments in AI infrastructure and drug discovery, showcasing the growing interest and potential in these sectors.

Links

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