DOGE unveils a roadmap, Unlocking GDP Growth, WW3 escalation, Fat cell memory

27:09It's not going to have the decrease of freedom to act, but we also don't have as big a problem. what we need to do is to spend our fiscal to purve from being unsustainable to being sustainable. And if we can do that, it will have a huge impact on the economy. Specifically, what we saw in the last election, the thing that probably hurt the Democrats the most was inflation. Voters clearly do not like inflation. They do not like the diminishment of their purchasing power. But how do you stop inflation? You have to raise interest rates. And that's not good either because that raises the cost of mortgage, that raises the cost of a car payment is bad for investment, right?

27:46Because if interest rates are higher, then that means the discount rate on stocks and real estate on every investment class basically is higher. And the hurdle rate for investments higher. So high interest rates are also bad for the economy. So how do you get out of that box where you either have high inflation or high interest rates? The only way is to bend the fiscal curve to that more sustainable path. And if you can do that, The bond markets will actually give you credit for it in advance because they know that they're not going to be flooded with the need to keep funding all of this US government debt.

28:24So we either get to kind of start off with saying about being either default alive or default dead. We either get to default sustainable or default unsustainable. Right now we're unsustainable. The bond markets know it. Inflation remains persistently high. around 3%, the Fed has not been able to cut interest rates the way that they expected to remember. The markets were expecting seven cuts this year. We got basically three. We got a 50 and a 25. So it's just now hasn't been the cuts that people were expecting. And that's because inflation hasn't come down as much to a thought. So if Doge working with the rest of the government, OMB, the Treasury, Congress, Executive of orders can now convince the markets that the US financial picture is more sustainable.

29:07We'll get credit for that. Interest rates will come down and that'll lead to a boom in the economy. So it's all win -win if they can pull this off. Prebrick, any final thoughts here before we move on from Doge, wishing, Elon, and Vivek as much success as possible. We really, I mean, everybody should be rooting for this. You want to give us your final thoughts? I feel like America is Neo from the Matrix where there was like a thousand bullets being shot at America and we like literally had to dodge every single one of them in order to get to this point. I again, I am so shocked and surprised in a positive way that we ended up on this particular timeline.

29:53Look, everything had to go the way it went for this to happen. Biden decided to run for reelection. Biden stayed in too long. They didn't run a primary. They put Kamala in Elon, that was the fences switch parties. Elon, Elon decided to throw a hundred million bucks at the problem. Elon bought Twitter China had a real estate bubble. I mean you can go down the list of things that have to go right for us to get to this very moment where a small group of people have recognized the fiscal debt spiral that the United States federal government has been in and have the authority and the capacity and the skills to be able to go and execute against a solution.

30:34I have no idea how this could have been architected, maybe sacked you all along and I convinced him two years ago that this was how things had to go and he's been designing it like ever. You're talking about Ray Dally on the end of the empire for three years on this podcast as maybe you did freeberg We give you credit when when we talk with Dally about this. He's like I've been a handful and also around The the relationship with China, which I think this is all very tightly related We may have dodged a lot of bullets Hmm, and if the United States can get a task in order reduce federal spending while increasing economic activity It can be a tremendous unlock for the US and for world peace.

31:15So, because again, I think that conflict arises when we don't have our own fiscal house in order. And so I feel very positive, more surprised and positive than I was a year ago, six months ago, it's just amazing we're on this timeline. And I do think the United States as Neo dodged a lot of bullets here. Absolutely. I told you everything was proceeding as I had foreseen. The U .S. You know what happened to the tenure, and Elon and Vivek wrote that essay. I actually don't. What happened? Heels contracted by five basis points. You know what the value of that is? Couple billion. 15 billion per year.

31:49Yeah. Yeah. So I think that it was probably a hundred billion dollar essay, just writing it. I think you will find that this doge is quite operational. I mean, I think it's got a chance. I mean, if you can't, I think it's a wonderful. right? I want all Americans and Democrats to stand up and say, this is the right thing for the United States. Absolutely. Absolutely. And the problem is, the essay saved us a hundred billion, just the essay. Here's the, you're going to need a day. They're going to have to be very strategic about how they detailed what they're doing. Yeah. The, the, the doge teams is going to have to be very strategic to pick things that are consensus building that don't make people feel like this is going to grind the poor more and make the rich richer.

32:40That's the expectation. That's going to be the negative framing on the CypherDec, which is just a bunch of rich guys making cuts, talking their books, making cuts for things that are their pet projects, their investments. They have to come out and not make it that. They have to make it. Here's inefficiency, here's inefficiency, here's inefficiency. And a great way to do that would be to say the efficiency gains and the tax cuts are going to go to people making, let's say, under $250 ,000. These These cuts are not being made just to make the rich richer. That's going to be the framing. But just my best advice.

33:12Don't you think that that's going to happen no matter what? What? Which part of it? That they're going to say that no matter what. So I actually disagree with the first part of what you said. I agree with you that the media, the mainstream media will try to characterize this as hurting the poor. I agree. And I'm not sure yet what they're starting on. But I think the first part I disagree with is I don't think they should operate towards its consensus. I think that they should do what's right. Well, you could do what's right and you could start with things that are the most wasteful. Like if you start cutting kids' lunches or palgrants or you start cutting people's jobs to healthcare or education that people perceive are helping people, I think you're going to just feed into this narrative that it's a way to cut taxes on rich people.

34:01And you know what? You do need to build consensus. How does that cut taxes on rich people? With you cut regulations and a bunch of our companies benefit from it, just to be self -aware. The framing is already that this is an effort for companies that we invest in to have less regulation to make the equity holders in those companies more rich. I have to make sure that the hold on is for all Americans. You have to make sure the savings is for all Americans and that all Americans benefit from it. and the way they benefit it, the best framing they could do is your taxes are going to be lower because you're not wasting your tax dollars.

34:37If they can keep to that, not, hey, we're moving regulations so that our company is to be honest with you. Being a hairdresser requires more regulation than being any one of most of my companies. So I actually think it benefits. I think it benefits other people way, way more than it benefits me. And you have to show it is my point. So what's showing that's the point is you have to show people that you're doing this for everybody, not just for the people on this podcast and our friends. That's gonna be the key. What Jim Optus said is so important. There's a great interview. I've mentioned this in the past between Tim Ferris and Charles Koch from a couple of years ago where he brings up this exact example about how regulatory burdens make it difficult for women to become hairdressers.

35:17It's like $7 ,000. So they don't have the capital to do that because of the regulatory burden to get there. Think about building your home or, you know, So like let's say you want to put a shower in your bathroom, change the shower in your bathroom. You don't want to spend $15 ,000 on all the permitting regulatory stuff to make that happen. It's going to unlock value for everyone. That's a small example of kind of a regulatory problem, but this benefits everyone. And the cost of transportation will have to communicate that. You have to be able to communicate that. And that's where using the launch platform.

35:50But the latest four days, you've got a perfect job of communicating this to people. And that's the playbook, Freeberg. That's my point. People are gonna fight this. You have to convince them. You have to show them that this is helping everybody. Can we just agree that they're okay, but that's different than how you started. You said, only work on consensus projects. I know I did say that. I think you have that. That is why I like those. You said it at the beginning. I said, do those first. Make sure that people understand this is to save them money. I'm not saying that you don't change regulations for spaceships and self -driving cars as well, but you have to make sure you show people that this can benefit them or else they're going to just fight it.

36:26And that's going to be the whole, all this effort will be for naught. If you get a bunch of Republicans, SACs who start fighting this and you have a splintering in your party because they feel like this isn't helping their local constituents, this whole thing could be for naught. That's my story that you told is going to be told by the legacy media and all the haters and the enemies regardless of what Elon is going to do. I don't think so. I think if you show people at you show people at you show people at 22 hours on haters you're not going to win the show. I'm talking about the public who votes.

36:59We're ready to show election. Now's the time to implement when you show people $22 ,000, you know, hammers and wasted money. You will get 100 % of Americans backing this. No, 60 minutes, but after 30 years, nothing's happened. We got to just act now. Yeah, act and bring people on with communications. I mean, if you got if you're not, if you're communicating poorly, great. I'm not. Yeah, I'm not saying the communication isn't part of the job. In fact, this whole conversation started by us talking about an op -ed. Yes. Yon of a vague road. Correct. And there's a podcast right? And what's there laying out their objectives and they're doing podcasts and Yon has the biggest platform in the world and biggest following.

37:38So I just don't think communications can be the problem. But you're also not going to be able to convince everyone. And you know, we've already won the election. And now's the time to figure out very strategically how to implement as much as possible. Be humble by two million votes. Keep it in mind. You have to bring everybody along. Okay, you know what? If the last video is fair, it would have been 20 million votes for Trump to have won under these circumstances. And he won the trifecta. It's impressive. Nobody saying it's not impressive. I'm not minimizing it. I'm just saying be aware there are 74 million people who are rooting against Trump and I think getting some portion of them on.

38:14That's not true. That's not true. I think there's a decent number of people who are probably very upset that Trump won. Just like last time they were upset that Biden won. Including all Americans in this is the most virtuous thing you can do. I think it's strange to get on board. I think it's to range the idea that 74 million people are actually rooting against him. I don't think that that's true. I don't think they feel good that they lost. People don't feel good about losing. bringing those people on board is virtuous. Do there's a lot of convergence in the country? Have you seen the Trump dance?

38:46I mean, there's been such a five shit. Let's see it. Let's see it. I'm not going to do it right now, but there's been such a huge five shift that the energy is so optimistic right now.

38:58The energy right now is incredible. And I think people are feeling much more optimistic. Can you imagine what a downer would it be if like we were expecting President Kamla I would be a downer to it would be a downer to me if there were still pushing a $7 .2 trillion federal budget next year It that would be a downer and by the way I think that there's a deeply linked relationship between social issues economic issues political policies and Foreign conflict they all seem like they're four different things, but they're so tightly interwound And it's interesting how everything kind of moves together with this shift in who ended up wanting winning this election cycle.

39:38And I think it really speaks to the relationship between the four. Well, by the way, there's a great meme that was floating around where it showed a photo of Trump, Elon, Bobby Kennedy, and Tulsi Gabbard. And it said that all four of the fuel used to be Democrats. Yep. Oh, and we're joking in it. I tweeted that. I'm really joking. It used to be that Democrats were progressive. Progressive means progress, looking forward. And the last decade, the last couple of years in particular, I think a lot of people that I know that are former Democrats, and Jamal, if you can speak for yourself, feel like the Democrats stop looking forward.

40:16And it was all about trying to like repassumistic and grievance and venture. And all of a sudden you've got guys like Elon promoting themselves as Republicans, highlighting that it's all of the, this is the party that looks forward. This is the party that drives progress. It's an amazing shift. I don't know if there's been anything like it that's happened this quickly. I voted more to make America great again than I did vote for being a Republican. I think that the Republican party, right, totally, is less important than it's ever been. And I think MAGA is more important than it's ever been. I agree.

40:50And I'd say the biggest risk to the whole agenda, it probably is not the Democrats. It's actually some of these old bulls in Congress who are anti -magic for some reason. Trump is the one who just won the trifecta, he just won this big election. If you stick with the old Republican message, you're just a surefire loser. So give Trump his due as the leader of the party realizes now a maggot party and let's get some things done. If the reform agenda fails to be frank, it probably is not going to be the Democrats. that's probably going to be these holdouts in their public company. Yeah. Yeah, that was my question earlier.

41:30I think I asked it twice. I didn't get anybody engaged in it. How do you convince them? How are they being brought on board to this if they have all this pork barrel spending? Is there a strategy there? Would you have a strategy? I think Saks laid it out, which is that if you use the combination of the carrot and the stick, I think the carrot is creating transparency. And I think the other part of the carrot is you'll have now an extremely well -funded pack that can support people who are on board with this agenda. But the stick is, if you don't, I think that if Elon makes this a really concerted long term part of his strategy, then I think you should run candidates who actually are aligned with the agenda that the Make a Great Again movement wants.

42:15So I think that's the carrot and stick Jason, which is like some of these old Republicans will have to decide do I Basically help invest in a renewal of the American spirit or do I keep pushing back because I like the way it was and I want to go to war and I want to cozy up to these lobbyists. I think those folks are gonna have a very tough Four and eight years because I think you'll see a bunch of magick candidates rising up to run against and everywhere in the United States as As you can see my young apprentice your friends have failed now witness the firepower of this fully armed and operational battle station man I said to be humble like three times none of it's sinking in No, I just explained I explained the rest I I've been very clear.

43:00You're not gonna get molded Freeman Okay, you're not gonna get hovier Malay well we can hopefully get is a bending of the curve towards sustainable I'm sending my I'm sending my expectations to be realistic. I mean, breaking even would be great. If we just weren't adding to the debt, that would be amazing. No, I mean, go about, go about. Go ahead. Look, if the federal budget gets the $3 trillion and regulation gets cut, if you get 50 % of the regulations in federal agencies cut, I think you unleash an economic sonic boom. I'm all in under. I think it's the greatest thing that could ever happen.

43:36My gosh, can you imagine America clocking in? Do you guys deal with regulatory? I mean, how much of you guys start with companies? Zero. I'm dealing with regulatory. The regulatory stuff is brutal, man. I mean, it's legit brain -like melting sh**. Tell me your number one regulatory frustration. We can go around the horn. This is a great topic, actually. I don't have any. I think I'm very blessed to work in an industry that's very light with regulation. I think it affects many, many other industries that if they were unleashed could contribute to American EU -exception. Real destruction. And also the regulations are very regressive because they touch poor and middle income people way more than a touch folks like me.

44:18And so rip these regulations out. Two regulations that do affect you, crypto regulation and capital formation. Both of those things are massive. They haven't hurt me. I wasn't my point of view, but they definitely are spotted in the economy, I can snap a finger and raise a couple billion dollars. So I'm in a unique position and I recognize that. What is much harder is if you're trying to be an electrician, if you're trying to be a hairdresser, if you're trying to be a massage therapist, when you have to spend 15, 20, 30 % of your salary on licensure, why? Why do we need these stupid rules? If you're a person that's trying to construct a home, why does it take six and eight weeks to get through?

45:00It's approved. Why? I know there are no good answers for these things. So forget about me. Like it doesn't matter about me, but the main line part of the United States economy as I said before is a coiled spring. If you get rid of those regulations, it disproportionately impacts middle income and lower middle income jobs. This is why if you if you see if you see GDP, if America clocks in GDP at four to four and a half percent. Watch out folks, Sonic Boom. Watch out. I'll give you two really simple ones, allowing everybody in the United States to participate in company formation would change everything.

45:3995 % of the company cannot participate in investing in startups or any new companies which are the most crazy. I think it's more about just massive freedom to operate, just freedom to do stuff you Well, that's what it is. You're free to go to Vegas and gamble. You're free to play online sports, but you're not free to buy Bitcoin. You're not free to buy. You're not free to buy Bitcoin. You can buy it now. You're not free to token. I'm not sure that that's the regulation. I think there's many more traditional forms of economic growth that we can have before we need to make ICOs legal and easier.

46:19I want to say something. I think that the person that runs for governor in California should commit to cutting those 65 ,000 regulations down to 10 ,000 as needed to replacing the DMV with a digital app and to cut taxes to mere zero and to create school choice. Whoever does that will create a renaissance in California. It's the fifth largest economy in the world, folks, and it can be a bell -whether for the rest of the Well, you know, there's a lot of scuttle but online that Nicole Shanahan's going to run for Governor of California. And I'd be all in favor of that. I would say that of all the political personalities involved in the election over the past year, she gets my most improved award.

47:06I remember when like Bobby named her to his ticket, I was a little bit skeptical of that choice because of some of the causes that she had identified with or donated to in the past. but she I think has ended up being a star. She's pretty based. She's a star. Yeah, totally. I mean, she's red -pilded and ended up supporting my hat and my gut. And I don't think we're going to get anyone better in California. So she's willing to do it and take it on. That'd be awesome. Sex? What about you? You don't want that mansion? It'd be a significant downgrade for me. That's about to say. I'm going to go right out and go right back to it.

47:42Damn it. That was such an easy one. Yeah, you could live in the governor's mansion. Also known as Smarva, then your guest house. That would be your backup man cave. Well, actually, that's happened. People have in New York, I remember one of the governors was like, yeah, you know, I'm good. I don't need to live in the mansion. Where do you want to go next, boys? We have other things on the docket. Would you like to go for a war correspondent? Would you like to go from Google breakup? Would you like to go in video? Where would you like to go? World War Three, I think, is important. Sax, you put World War III on the docket.

48:13Would you like to tee it up for us? Sure. Well, there's several events that have happened in reasonably close succession. The first thing to understand is what's happening on the ground in Ukraine. The Ukrainian has been losing territory at an accelerating pace. There's an excellent graphic in the New York Times that I'll put on the screen that shows this. It's not a stalemate memorized on this podcast six months or a year ago that it was no longer a stalemate. It was a war of attrition in which the Ukrainians were now losing. And every single month now the Russians are taking more and more territory.

48:45Again, the curve is accelerating. We had all invested in a business who had a growth curve that looked like this. So not good news for the Ukrainians. In response to that, I think that's the funnily the condition on the ground that's created the next set of actions, which is the Biden administration finally approved the use of long -range missiles, attack them's missiles, storm shadows to hit territory deep inside of Russia. The Russians believe, and I don't know whether this is true or not, but what they say is that those weapons cannot be operated without Americans or British operators being there to, you know, they're too complicated for the Ukrainians to use on their own.

49:22So the Russians view this as not just a direct attack on their homeland, on their motherland, but also a direct involvement by the NATO allies, the United States, and Britain in the war. And that is a big escalation. You know, a lot of people say that the Russians have all these red lines. We keep crossing them and they don't do anything. That's not true. If you actually listen to what the Russians have said, there's only been two red lines. The first red line was they said they would not accept NATO expanding to Ukraine. And they They proved their seriousness on that issue by invading Ukraine in February of 2022.

50:02The second red line is they said that they would not accept American long -range missiles being used to target inside Russia. And that line is now being crossed. So this leads us to the next set of events, which is Russia just used what may be some people are saying it's an ICBM, but it probably is more likely to be not an intercontinental, but an intermediate range ballistic missile that hit a Ukrainian city. And it's obviously it didn't carry a nuclear payload, but it's the type of ballistic missile that is used to carry nuclear weapons. There are a couple of features of this that I think are really important.

50:44Number one, it's a hypersonic missile. It hit the target at something like Mach 10. What that means is that it just can't be intercepted as too fast. the West and the United States in particular does not as far as we know have a technology to intercept a hypersonic missile like that. The second is that it had what's called a MIRV Warhead or Payload. MIRV is multiple independently targeted reentry vehicles basically what it means is the warhead splits up when I guess close to the ground it splits into six separate warheads and the reason for this is I understand it is diabolical. Again, it's just if you're launching nuclear weapon, it just makes it that much harder to now intercept it because now you've got six warheads hitting you instead of just one.

51:30So I mean, as I understand a missile like this has never been used before and what the Russians are doing obviously is sending us a signal and what that message is is that they're saying we have the means to hit any European city or any European asset with a hypersonic missile that you can't stop that may or may not have a nuclear warhead attached to it. And it's just a way of them expressing their seriousness and displeasure and reacting to an escalating in response to the fact that we are now allowing Western missiles to be hitting targets deep inside of Russia. So the bottom line is this war is escalating, so escalating nowhere good.

52:13And at some point soon... Yeah, it's really. We're gonna have to get off of this escalatory ladder. Or we're gonna end up in a really disastrous place. And the last final point is, it's absolutely remarkable that Biden decided to take us to this place with what? Just six weeks left in his term. Completely. He's a lame duck president. What is his mandate for doing that? For taking this extraordinary risk on behalf of the country, the voters devoted for Trump who made it really clear. he wanted to end the war and Biden and his team have unilaterally now escalated this war. They did it without consulting with Trump's team.

52:50At least that's what was publicly reported. Is there was no briefing set up for Trump's transition team. So you have here Biden, his team taking a unilateral action to expand and escalate this war, even when he's a lame duck president. And the question you have to ask is why? What is the point of this? Well, I think it's just completely deranged because it's not just that, But forget Biden and Trump for a second. If you take a step back, what was voted in was to end this war and for the United States to get our hands out of it. So you couldn't have a clearer message to the sitting president in the White House, which is this is not what Americans want.

53:32And so to basically ignore the will of the voters and to essentially go and push another country into the brink, I think is so incredibly responsible. And you know, other times we've said in the past, take Donald Trump seriously but not literally, Russia you should take seriously and literally because they actually write it down for you and tell you. And so when they said every act of aggression from now on is going to be viewed by us on a look through basis to the actual country that is enabling this to happen, you couldn't be more clear, but Americans couldn't have been more clear, which is we don't want this war anymore.

54:12And I just think it's really deranged what the Biden White House is doing. It's incredibly dangerous. By the way, not to mention, it's incredibly costly as well. I mean, we've had like some last -minute efforts to sort of tamp down on these last -minute budget approvals and whatnot, but we're talking about tens and hundreds of billions of dollars that we're giving on top of the risk of nuclear escalation. I just think it's absolutely crazy. It's absolutely crazy. Putin is not a dummy. He has heard and seen Trump's campaign rhetoric and sacks, I don't know if this has been publicly reported that he had a call with Trump after the election victory.

54:53Does Putin not see that in a couple of weeks, a couple of months, there will be new leadership in the White House and there's going to be a path to a resolution here. like does that not give us all a little bit of reprieve that this is not going to escalate because everyone's waiting for January 20th? Oh, I mean, for sure. I mean, thank goodness. I would say that we have a new president coming in who does not own this war. I mean, the problem with Biden is that he completely owns this war and he does not want to emit defeat. And so what you've seen is that over the last couple of years, every weapon system that Biden said he wouldn't give to Ukraine because it could literally cause World War 3.

55:30these are Biden's words. He said it could be Armageddon. If we gave Ukraine F -16s, it could be Armageddon. If we gave them Abrams tanks, it would be Armageddon. If we gave them high Mars and attack them and could lead to World War III if we let them hit targets inside of Russia. These are Biden's words. And he has basically given it on every single one of those points because he's so committed to this policy, right? He's in the Quagmire. He can only double down. He doesn't know how to extricate himself. And now we don't know exactly what Kamala Harris would have done but i think probably she would have inherited joe bines policy and likely continued it and i think we have a wonderful opportunity with trump taking office he doesn't know this policy you can look at it with fresh eyes most importantly he campaigned on ending the war so he has the mandate of the american people to stop it all i can say is thank goodness and we just need to get through the next two months we seem to get to jenary twenty -eighth without there being some new horrible escalation in this war.

56:31He's, and Biden is Martin Galing. That's his strategy for the Ukraine Russia War. Just keep doubling down and doubling down. Doubling down. Oh, yeah, do you want to explain what that is? Oh, yeah, sorry. Martin Galing is a strategy in gambling where let's just say, you know, you start betting a dollar and you lose, your next bet is $2. If you lose, your next bet is $4. If you lose, your next bet is $8. dollars and eventually you'll win once is the theory. But there's many times where Martin doesn't know it, but you only won a dollar. So you could be betting, you know, 80, you know, 40 bucks, 80 bucks, $160, $320, and then you finally win and you win a dollar.

57:10Right. Or you go broke. That's a great analogy because you can also go broke, right? Well, this is why I have caps at the roulette table. One time I would do this as a joke. All just, you know, it's have a max. Yeah. Yeah. So I would do this as a joke with my wife, but when I was at the World Series, a poker, I'd be like, I'm going to pay for dinner or lunch or whatever. And I put a hundred dollars on black, lose, put 200 on black, win, go pay for lunch. And I did it one time at the WSOP and I went 100, 200, 400, 800, 1600. I ran out of cash. I got 3200 from my friend. I put it down. The floor man came over and said, that's your last bet.

57:46Oh, no, my buddy. And I would stop if you do this. Yeah. In our college years, early 20s, we would go to drink for free at the casino. You just sit at the blackjack table and just keep going. Yeah, I've been with you a dollar a while. I've been with you a dollar a while. I've been with you a dollar a while. I've been with you a dollar a while. I've been with you a dollar a while. This was a long time ago. This happened last year. So I'll wait, well, I mean, if you bet a dollar, then you bet two bucks. You can just keep drinking for free for like two or three hours. Then go out and enjoy your night.

58:09You've made 15 bucks and you call it enough? Did I tell you about the losing a million dollars playing roulette? Oh, what? Me? Nick, you gotta be about the names. Me. It was me. And you did tell me this. You did tell me this. Yeah, this is so good. Says, guys, I've developed a system. It's four. Oh, no. That's always what happens before you lose a billion. And sometimes that. It's like, we need to risk a million. We can win like two or three. And it's like 99 .996%. So I say to them, So are you really telling me that we just have to fade? 0 .004 percent chance of like total loss. And he says, yep, well, guess what hit the point zero zero four percent chart.

58:58Me. And it was devastating. I just kept looking at this thing like what just happened. He's like, uh, we lost. Yeah. And I was like, there it is, folks, I never again. I've never going to play roulette again. I think the gambling analogies are the right analogies because I look, I'm not saying World War III is going to happen. I've never said World War III is going to happen. I'm saying that there's a risk of World War III. And I don't need the risk to be very high, to be very worried about it because it would be such a disaster. Trump come, right? Totally. Exactly. So I want to minimize. Risk of ruin.

59:27Exactly. I want there to be hopefully a zero risk of that. But you know what's interesting is, remember just like a week or two ago, President Trump made that trip to DC and he met with Biden in the Oval Office and Biden had this, he was like, all smiles. And everyone was wondering why is he so happy? And the speculation was that he somehow wanted to come to the lose or something. But now you think back on this, he must have known he was about to authorize this decision. So what he's doing here, he's grin f***ing, he's grin f***ing Trump. He knows he's about to give Trump this horrible hand, right?

1:00:04He's about to make this situation in Ukraine so much worse So that's what I have to inherit this mess. That is like the definition of green Yeah, he definitely knew more than that picture let on because the interpretation of that picture was They are getting along. He's being super gracious. What an incredible gesture and it just looked like very Yeah, he promised a smooth transition of power and then we find out that he didn't confer with his successor about about this extraordinarily meaningful decision to escalate the war. Escalation, yeah. It's like, that's just crazy. It's crazy. You guys wanna do science corner?

1:00:45I got one for you. Yeah, let her. Yeah, sure. All right. Your super fans are desperate for a science corner. Give them what, Freiburg? Give them something. All right, I will give you guys something. Here's a depressing paper that was published in the journal Nature, just this week. research team out of Switzerland going over to the Swiss where they are conducting extraordinary research in the epigenetics of fat cells in the science corner. Go ahead. Great. No, we're actually going to understand perhaps why it is difficult for people that have been overweight. Yes. To keep the weight off. I did this and I think it's fascinating.

1:01:28Yeah, explain it. It is it is really incredible. So remember we've talked about this many times in the past but every cell has your whole all your DNA, all your genes. And certain genes are turned on or off in different cells and those genes being on or off differentiates those cells and causes them to act differently. That's the difference between an eye cell and a skin cell and a heart cell is they have different genes that are up regulated down regulated turned on and turned off. And even when you have different kinds of cells you have certain genes that are overexpressed or under expressed or overregulated or upregulated or downregulated.

1:02:00That means that those genes are turning, pumping out certain proteins that do certain things in that particular cell. So what these folks did is they wanted to understand what is the epigenome, meaning what are the genes that are turned on or off or upregulated or downregulated in fat tissue and fat cells? And does the epigenome change when an individual loses weight? So once they're obese and they lose weight, do the fat cells actually change their epigenome or do they have an epigenetic memory? Meaning that those cells, even though the person has lost weight, those cells still continue to act as if that person were obese.

1:02:45So I'll tell you in humans, they basically took five individuals that were obese and lost more than 25 % BMI. And they looked at the epigenome, they looked at the markers of what genes are upregulated and downregulated before and after they lost the weight. After they lost the weight, there were a set of markers that were still upregulated that are associated with poor metabolism, an increased fibrosis and increased cellular death. So these are inflammatory genes, these are genes that are associated with the cells being inefficient that utilize glucose to create energy. And so these cells continue to act like slow dying cells even after the person and lost weight.

1:03:24And they did the same thing in mice and they found similar results that they caused these mice to gain weight, looked at the epigenum of the fat cells and then looked at the epigenum after they lost the weight. And again, the mouse epigenum continued to act as if the mouse was obese. And what this means is that the metabolism remained reduced, fibrosis remained elevated and likelihood of cell death remained elevated. So now they applied glucose in a petri dish to those cells And they saw that the glucose had a harder time being fully being appropriately utilized from a healthy Fat cell that hadn't been obese So it actually permanently alters and creates an epigenetic memory in the fat cells after obesity and this could explain Pretty significantly why when people that have been obese lose the weight They are more likely to gain the weight back and have a hard time keeping the weight off you're referring to yes.

1:04:19And that makes total sense because anybody who's added weight to mouth if that you add but you know, you eat one extra Oreo a week. That's 3500 calories. You do that over 20 years. Obviously, you wake up one day or 20, 30 pounds overweight like I almost three or four years ago. And this is why I think ozemic and wagovian, and on journal and all these things are so great because it does seem like it breaks you through that. No. Well, the problem, but we do see in all those results that when When you go off of the GLP1 Agonist grugs, you gain the weight back very quickly. This is some amount of weight.

1:04:53No, it's not the total amount. It's a pretty significant bounce back effect. This is pretty well documented. I think that it speaks to the why. It also introduces an opportunity. There are molecules that can turn certain genes on or off, can now be identified and utilized to change that epigenetic memory. So now there's a switch in addition to that switch. Exactly. This could arise from things like increased exercise. It turns out that when you do significant amounts of cardiovascular exercise, there are certain genes that are expressed that trigger other genes to switch on or off. And so we can start to identify those particular molecules and produce either supplements or additional drugs or combo therapies that can both knock the weight off and keep it off by changing the epigenetic memory in those cells.

1:05:43Wow. And so it introduces a whole new class of opportunity for folks to explore. How do we help folks that are obese lose the weight and then flip the switch that they can keep the weight off? I've been doing rocking. This is like the old man activity that Peter Atia and these guys are all popping up. You can wait until I'm in you like go walking. I wear a, I started with a 10 pound weight vest now I'm at 35 pounds. I do a mile and a half hike every day with 35 pounds on. man, I fall asleep immediately and the amount of intensity that puts on your body. You do it right before you go to bed. No, no, I do it anytime during the day, but I'm just saying it's, I'm focused on four things right now with my health diet, sleep, exercise, meditation, and I try to do all four each day, but the rucking specifically in the zone two stuff is what they say 40, 50 year old should focus on.

1:06:32So that's what I'm focused on. But that rucking man, does it make your whole body strong? How they recommend it? It's really transformative. My meditation is reading Doja for Chamath Polyhapatia. German dictator 8090 is running a software company services company. Great. Look at you in the driver's seat David Friedberg, your sultant of science working on a hollow and the architect the rainman. Yeah Yeah, definitely David Sack from Craft Ventures and maybe he's gonna be involved in Doge. I wouldn't be surprised if we see a Sack Doge hook up in the future. I don't know. I'm taking a guess here. I am your host here, Jason Calcanus.

1:07:14See you all on December 7th, live or in person. By the way, did you guys see this spectacular? Did you see this tweet from Brian Johnson? He tweeted out all of his blood levels. This is incredible. I love this guy. Look at these results. They're incredible. If he can break this down into like a turnkey thing that normal folks like us can Follow for people who don't know What this kid's doing is he is spending like three million dollars a year or something to that effect on his own personal health documenting and sharing it everything from sleep who has bone density, everything is an open book, and he's made some products out of it as well.

1:07:56So you can eat his pudding to him if you're interested in it, but I don't think it's as good as he's got a full load of his regimen. You know what I mean? It just seems too hard. You can't have a job. I mean, he's doing, it's like he's got two jobs right now, doing all this stuff. His biomarkers are showing he's 10 years younger than his actual biological age. Dude, look at some of these results. His speed of aging, he says his birthday now happens every 19 months. What the f***. Freeberg. I mean, freeberg, you look at what do you think your science, from a science perspective, any thoughts on all this?

1:08:32Well, I think his nighttime erection rate is pretty impressive. Not three hours and eight minutes for nighttime erection. How does you reading? Is he reading Elon of the Vex hop at call? Slowly, he's reading it very slowly. Wow, he's got a 240 pound bench press and an 800 pound leg press. Jesus. He looks like he's dead though. That's the only problem with that. He's so fell. Sax has got to go. DJT online too. We'll see you all next time. Oh, in. I love you boys. Bye bye. I love you.

1:09:15We open source it to the fans and they've just gone crazy with it. Lumby West, I squeeed a king of wilds. I'm going all in. What? What? What are we going to try? I'm going all in. Besties are gone. Go for it. That's my dog taking a wish. You're driving away. Sit down. Oh man, my ham is the actual meat. We should all just get a room and just have one big hug or two because they're all What? You're the B. What? You're the B. B. What? We need to get merchies already. I'm doing all this.

1:10:01I'm doing all this.