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16 episodes

Business Of Biotech

by Ben Comer · English

The Business of Biotech is the pod dedicated to leaders of emerging biopharma firms. SUBSCRIBE to our new newsletter at www.bioprocessonline.com/bob. We bring you insight into organizational, finance and funding, HR, clinical, manufacturing, regulatory, and commercial challenges you’ll face as you navigate your company from an idea to success in the clinic and beyond. Each episode features guest commentary and best practices from accomplished founders and biopharma industry luminaries. The Business of Biotech is produced by Life Science Connect.

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Managing Risk And Development In A Growing Neuroscience Portfolio With AbbVie's Sean Kelley

How AbbVie (Sean Kelley) manages neuroscience development risk after discovery—covering clinical decision-making, diagnostics/biomarkers, formulation/device and delivery, portfolio balancing…

9 Nov 2026 · 50m · 19 chapters

Translating A New Discovery Into A Novel Cancer Therapy With Grid Therapeutics' Ned Patz, M.D.

How Grid Therapeutics co-founder/CEO Ned Patz, M.D. translated an academic discovery at Duke into a clinical-stage cancer antibody program, focusing on GT 103 (a completely human-derived antibody…

2 Nov 2026 · 54m · 25 chapters

Bioprinting 3D Human Tissue To Discover And Test New Treatments With Viscient Bio's Keith Murphy

Keith Murphy discusses bioprinting 3D human tissue models for toxicity testing and disease modeling, aiming to improve drug safety decisions and reduce development costs.

26 Oct 2026 · 57m · 21 chapters

Investing In Tomorrow's CNS Breakthroughs With Breyer Capital's Bret Bostwick, M.D.

Dr. Bret Bostwick, venture partner at Breyer Capital, discusses investing in CNS breakthroughs and how programmable therapeutics (especially Watson-Crick base-pairing oligonucleotides like…

19 Oct 2026 · 47m · 26 chapters

AI, China, And Biotech Investing With SR One's Simeon George, M.D.

SR1 Capital Management’s biotech investing approach, and how AI and China are reshaping drug development.

12 Oct 2026 · 49m · 21 chapters

Reprogramming Cancer And Competing With China With Earli's Cyriac Roeding

Cyriac Roeding (Earli) explains how the company uses AI-designed genetic switches delivered by engineered lipid nanoparticles to make cancer cells produce immune-activating drugs locally, aiming to…

5 Oct 2026 · 1h · 22 chapters

Growing And Scaling A Radiopharmaceuticals Company With AdvanCell's Philina Lee, Ph.D.

Advanced Cell’s CEO Philina Lee discusses scaling a radiopharmaceutical company focused on targeted alpha therapies for prostate cancer, including ADVC001 (lead-212/PSMA) clinical differentiation, a…

28 Sep 2026 · 55m · 21 chapters

Finding New Opportunities In Obesity With Moonwalk Bioscience's Alex Aravanis, M.D., Ph.D.

Moonwalk Biosciences’ obesity strategy using adipose-targeted siRNA (not appetite suppression) to improve on GLP-1s.

21 Sep 2026 · 47m · 22 chapters

Biotech Finance And Investor Update With Independent Board Director Allan Shaw

Biotech financing and investor update—how improving capital markets change investor risk tolerance, what “conviction” and differentiation mean, how to align development milestones with the next…

14 Sep 2026 · 55m · 20 chapters

Funding A Virtual Biotech Without Institutional Capital With Sarcomatrix's David Craig

How Sarcomatrix (a late-2022 virtual preclinical biotech) is funding and building a drug development program without institutional capital, using creative financing, heavy outsourcing, and a lean…

7 Sep 2026 · 56m · 23 chapters

Picking Biotech Winners Beyond The Hype Cycle With Andera Partners' Olivier Litzka

How Andera Partners (Olivier Litzka) picks biotech and medtech investments across the hype cycle, using a life-cycle portfolio approach (early to commercialization) while navigating policy, AI, and…

31 Aug 2026 · 58m · 24 chapters

Biotech Investing At The Earliest Stages With Santé Ventures' Omar Khalil

Early-stage biotech investing and venture formation at Santé Ventures, led by managing director Omar Khalil.

24 Aug 2026 · 56m · 17 chapters

Getting To A First Product Approval With Celcuity's Brian Sullivan

Cellcuity CEO Brian Sullivan discusses FDA approval (July 14) of RevTorpic (getolalisib; tolisib) for HR-positive/HR2-negative locally advanced or metastatic breast cancer patients without a PIK3CA…

17 Aug 2026 · 50m · 21 chapters

Cell Therapy Advances And Biotech Leadership With Nkarta's Paul Hastings

Encarta’s allogeneic CAR-NK cell therapy for autoimmune disease, plus broader biotech leadership views on patient-centric drug development, cell therapy funding, and fixing U.S.

10 Aug 2026 · 50m · 22 chapters

A Rescue Model For Shelved Drug Candidates With Annette Bakker, Ph.D. And Andrew Lo, Ph.D.

Andrew Lo (MIT finance) and Annette Bakker (Children’s Tumor Foundation) discuss a “rescue model” to repurpose shelved drug candidates for neurofibromatosis (NF) and schwannomatosis, using a…

3 Aug 2026 · 56m · 24 chapters

Using Genetics To Discover New Treatments With Regeneron Genetics Center's Aris Baras, M.D.

How Regeneron Genetics Center (RGC) uses large-scale human genetics (and expanding proteomics/health records) to find disease targets and protective variants, accelerating new therapies and enabling…

27 Jul 2026 · 55m · 20 chapters