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Forbes Daily Briefing

29 Oct 2026 · 7m · 3 chapters

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Two Big AI Risks Revealed In Anthropic's New S-1 Filing

In short

The episode covers Anthropic’s new S-1 filing ahead of its IPO, focusing on two major AI risks.

Key claims

more than 90% of Anthropic’s code was written by its own Claude AI tool (Sept. 2026); Claude “closes the loop” by running experiments, generating training data, automating evaluations/safety audits, and improving efficiency. Financially, Anthropic reported $16.3B revenue and $693M operating losses in first six months of 2026, then $974M operating income in Q2 2026. Risk 1: faster AI development could outpace safety/security. Risk 2: AI used in labs/robotics could cause injury, damage, hazardous releases, or be misused for chemical/biological weapons.

Notable examples

Claude Science/Claude for Life Sciences; lab automation via microscopes, liquid handlers, robotic arms; customers include Bristol-Myers Squibb, Garvan Institute, and UCSF.

Guests

none mentioned in the transcript.

Written by AI. May contain mistakes.

Chapters

0:00

Anthropic's IPO and AI Insights

Discussion on Anthropic's IPO filing and its implications on AI development.

“When it's time to scale your business, it's time for Shopify.”
1:05

Anthropic's IPO and AI Insights

Discussion on Anthropic's IPO filing and its implications on AI development.

“That step brings it closer to what could be one of the largest public debuts in stock market history.”
2:52

Risks of AI Development

Exploration of the major risks associated with AI development as noted by Anthropic.

“According to the S1, the value of Anthropik's internal Claude usage at list prices has grown over 250 times from January 2026 to September 2026.”
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Transcript

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0:44Gemini and Chrome is here for it. Ready to make anything online make sense? There's no place like Chrome. Check responses set up required compatibility and availability varies 18+. Today on Forbes, Two big AI risks revealed in Anthropic's new S1 filing. Anthropic officially filed for an initial public offering, or IPO, on Monday. That step brings it closer to what could be one of the largest public debuts in stock market history. The company is slated to go public in the coming weeks. Anthropik's S1 filing on Monday was the first glimpse public investors have gotten into the AI firm's financials.

1:28It also revealed numerous previously unknown aspects of how the company functions and how it views AI's role in society. In the filing, it revealed that more than 90 % of the company's code was written by its own AI tool, Claude, in September. The AI giant is increasingly using its own AI models to research, design, and develop subsequent versions of its models, a process it calls, quote, closing the loop. In the S1, the company wrote, quote, The company says that Claude runs experiments, generates training data, and automates evaluations and safety audits. It has also helped make algorithmic improvements that allow Anthropic to use computing resources more efficiently.

2:20According to the filing, Anthropic reported$16.3 billion in revenue and$693 million in operating losses in the first six months of 2026. In Q2-2026, its first profitable quarter, it had$974 million in operating income. It's not surprising that Anthropik's 5 ,300-strong staff relies heavily on Claude, but the company now spends more on internal AI usage than it does on salaries. According to the S1, the value of Anthropik's internal Claude usage at list prices has grown over 250 times from January 2026 to September 2026. Thanks to Claude, engineers contributed over 45 times more code per day in Q3 2026 than in 2024.

3:13But while Anthropic lists Claude's ability to improve itself as one of its most, quote, significant structural advantages, it also poses a major risk. As Claude helps build future versions of itself, it compresses timelines and accelerates the pace of AI development. Antropic says in the S1 that a key risk is AI moving so fast that it could outpace the company's ability to develop corresponding safety and security measures. Flaws or errors present in current versions of the model could pass down into later ones, making them harder to detect and fix. Antropic isn't the only company using its own AI to train more AI.

3:55Its rivals are doing it too. To address these risks, Anthropic is calling for an industry-wide initiative to, quote, pace the frontier and allow for independent safety reviews of all frontier models. Anthropic expects to spend$1 billion over the next five years to build, quote, external reviewer capacity with Accenture. Meanwhile, Anthropic also trumpets its commitment to using AI for scientific research on the very first page of its IPO prospectus. The introduction reads, We have started to directly make biological discoveries with Claude. It notes that Anthropic expects the model to make more breakthroughs in the future.

4:37It's referring to the AI firm's own internal biology research, announced last month, where its software discovered a new enzyme family with properties similar to those used for CRISPR gene editing. The company has also built a number of products for scientists, including Claude Science and also Claude for Life Sciences, which aims to help in drug discovery research, as well as helping to produce FDA submissions and similar paperwork. Andanthropic has developed software that enables AI agents to operate lab equipment, quote, such as microscopes, liquid handlers, and off-the-shelf robotic arms, to help automate research, according to the filing.

5:18It name-checks customers like pharmaceutical giant Bristol-Myers Squibb, the Garvin Institute of Medical Research, and the University of California, San Francisco. It earlier made headlines partnering with companies like Lilly and Novo Nordisk. Along with the potential rewards of applying Anthropics machine learning models to research come significant risks, especially in the realm of scientific research. That includes its model's ability to operate robots and lab equipment, which it says, quote, could result in bodily injury, property damage, damage to costly equipment or experimental materials, or the release of hazardous substances.

5:59This could be due to misalignments in the models, or deliberate misuse. Additionally, the company warns that its models could be useful to people, quote, seeking to develop chemical, biological, or other dangerous weapons. While Anthropic says it has deployed technical safeguards against bad actors who want to make weapons, it warns that, quote,

6:33For full coverage, check out Rashi Srivastava's and Alex Knapp's pieces on Forbes.com. This is Kieran Meadows from Forbes. Thanks for tuning in.

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From the publisher

Anthropic filed for its blockbuster IPO on Monday, bringing the AI behemoth closer to what could be the largest public debuts in stock market history. The 335-page filing revealed the Claude maker generated around $16.3 billion in revenue for the first half of the year, up from $1.2 billion a year earlier, but incurred a $80.7 billion net loss for the first half of the year (most of which is due to a non-cash accounting charge). The company touts more than 300,000 enterprise customers, 250 of which spend over $10 million on Anthropic’s products every year. It plans to list under the ticker symbol “ANT” and is on track to go public as soon as mid-November.

Forbes estimates that its two most prominent cofounders: CEO Dario Amodei and his sister, Anthropic president Daniela Amodei, are worth $13.6 billion and $13.7 billion, respectively. Each cofounder owns an estimated 1.4% stake.

Read the full story on Forbes: https://www.forbes.com/sites/the-prompt/2026/10/27/inside-anthropics-ipo-prospectus-revenue-losses-and-surprising-details/
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