Episode 440: The Hidden Benefits of GLP-1s: More Than Just Weight Loss Medication

0:01Hi guys, it's Tony Robbins. You're listening to Habits and hustle. Crush it. Are there hidden benefits to GLP-1s that the FDA just isn't talking about? In this Fitness Friday episode of Habits and Hustle, I sit down with Dr. Tina Moore to break down the truth about GLP-1 medications and the hype surrounding them. Dr. Tina is an expert in holistic regenerative medicine. She shares why these drugs are more than just weight loss tools and how the conversation around them has become very polarizing. This is a short clip from our full interview, where you can find the full episode linked in the show notes below.

0:42Please listen and comment with anything you'd like. Enjoy the episode.

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2:15there's so much controversy over ozempic right like most people are like oh you know what like it's a it it's like the easy way out you're not learning you know how behavioral differences or habits you're just kind of taking a shot to lose weight and you are on the opposite side of the fence, right? You actually, you're a big proponent of using these drugs. Well, I'm talking, I was originally, about a year ago, I found all this data and literature, like 20 years of studies showing that this class of, they're peptides for one, they just happen to be owned by big pharma. Can you talk about what it is?

2:52Like what is, because I think no one really understands, like, is it a peptide? Is it a drug? Like, let's start with what GLP-1 is. It's a peptide. So it's a string of amino acids linked together by peptide bonds. So it's a peptide. We make GLP-1 in our bodies naturally, in our brain and in our guts. We have receptors for GLP-1s all over our body that do a whole lot of different things. It just was serendipitous that it got figured out for type 2 diabetes. It does a whole lot of other things in the body. And this was really interesting to me when I started studying it. It's a peptide in that it's in and out of the body very quickly.

3:25So the body produces it and the half-life is very short. the pharmaceutical version has been tinkered with so that the half-life is much longer. So the half-life is maybe four to seven days. So that's it. It's bioidentical, at least Ozempic, which is semaclutide, is bioidentical to our own GLP-1 for the most part. And about a year ago, I started finding literature outside of what most people understand it for. Most people understand it for reducing appetite because it plays on the centers of our brain that control appetite, for slowing gut motility so you feel fuller longer. And that's kind of where the story ends.

3:56That's kind of where people understood how it works, and that's why it's a weight loss drug, and that's why it's for type 2 diabetes. It has multiple impacts on our metabolic health in a myriad of ways that have a lot more to do than just that. And there are receptors in our brains, in our heart, in our pancreas, in our immune cells. And I started finding literature that was really, really interesting about this, and I started going on podcasts and sharing about it. and finding information like recent studies have come out showing significant reduction in all cause mortality for those who are on it, reduction in different types of cancers.

4:33Cancers? Colon cancer specifically. This was correlative, not causative, but they were finding they were comparing people on somaclutide versus, or even some of the other GLP ones for a period of time versus I think insulin. And not a great, I mean, it's not a super clear comparison because insulin is pro-grow, so insulin can cause problems in and of itself. But interesting data coming out there recently, 13 different types of potentially reducing 13 different types of obesity-related cancers. And then I was finding data and sharing out about potential protection against COVID and upper respiratory illness.

5:08And I was sharing about it on podcast thinking, well, if anything, I'm helping big pharma sell their peptides, so they'll probably leave me alone. I didn't think I was a threat there, you know? And honestly, the microdose is completely independent to the individual sitting in front of me. And that person, for that person, it might be the standard starting dose. Like that might be their microdose, right? So I have no idea. But then I started a second account a few days later and it grew to 15 ,000 followers pretty quickly. And it was shut down within 36 hours. And that's when I realized like, oh, somebody wants me to shut up.

5:42Right, right, right. Well, I mean, if you're trying to take business away, who makes Ozempic? Who's the company that makes Ozempic? Novo Nordisk. And then Monjoro is Trisepetide, and that's Eli Lilly. But I mean, I have no interest in keeping people away from the standard. I don't care. What's interesting is when I started talking about this, I was like, you guys, I'm finding all this amazing literature supporting GLP-1s for neuroregeneration and decreases in inflammation and neural inflammation, which I think is really cool. That's where I got most interested. And potential, there's studies being done right now on potential improvements in Alzheimer's and Parkinson's.

6:24And like, this is super exciting guys. And my followers, so many of them turned on me and they're like, when did you get, they were like, when did you get bought out by big pharma? When did you become a big pharma shill? So they're screaming at me in my comment section, accusing me of being a big pharma shill. And I'm like, no, I'm talking about compounded versions. You guys, I'm not even talking about the standard brand name, but if you want to use the standard, great. And many of the people that I talked to in my following have said, you know, I could only get a hold of the standard brand name through my regular doctor, through regular pharmacy, and it's changed my life.

6:57So I'm like, cool. You know, I don't have any favoritism either way. I'm just saying that if for someone like you, as lean as you are and metabolically optimized as you are, if you had maybe cardiovascular disease in your family or you were dealing with some kind of neurodegenerative condition, we would need tiny, tiny doses for you. So wait, like, so, so yeah, that's what's interesting. So in your opinion, should everybody be on one of these GLP-1, like an endozampic form for their metabolic health? I think that I get asked that a lot. I think that's kind of a bold statement to make, and I wouldn't say yes to that.

7:31I think the way that I've always practiced medicine is I'm just trying to treat the person in front of me and I'm trying, I don't use this in isolation. It's not a comprehensive protocol. So I'm a big fan of bioidentical hormone replacement. I've been using it in practice for a long time. My background was actually as a regenerative medicine doctor. So I was doing prolotherapy, PRP, stem cells, exosomes, regenerative therapies in my clinic for decades. So to me, peptides are just part of that. And this is just another peptide. But where do peptides even come from? I feel like the word peptide has become very popular, very trendy, only in the last few years.

8:12Like before, like five years ago, I never even heard of a peptide. Most of my friends never heard of a peptide. And then in the last four or five years, there's lots of peptides that people are taking, the BPC-157, the CJC-1290, whatever it is. There's so many. And I think, number one, it's inconclusive from what I've heard. And so people don't, there's not much, but most people don't know much about them. Right. And so it's scary. And I don't even think people that mass and I only say that for people who are in my world who are in the health and wellness space or longevity space or the fitness space.

8:49If I'm like confused, I can only imagine how people who are just layman's like, you know, an accountant working at, you know what I mean? What are we doing? Or someone in the marketing department at like Hasbro. Yeah. What do you mean? I feel like, can you start from the beginning? How did it become even something that was even to be taken for optimizing your health or for your longevity? Well, these started popping up in the regenerative medicine space, at least in my, when I caught wind of them, I would say 2017, 2018. And we use them short term and we cycle them. So say you injured your shoulder, we'd put you on a stack of peptides to optimize your shoulder.

9:35I would probably do some regenerative injections. You can even inject these locally to the injured areas. Like stem cells? Yeah, you could do however you want. They seem quite safe. They're strings of amino acids and they insert themselves in. Many of them have anti-inflammatory properties. Many of them have regenerative properties. And when I say regenerative, I think people get confused. It's not like we're going to drop some BPC-157 on a heart cell in a petri dish or some GLP-1 and it's going to make new heart cells. What I mean when I say regenerative in the regenerative medicine world is that often we're just a baiting pathology.

10:09So when you hurt yourself, there's a whole downstream process of cytokines and inflammatory molecules that happen as the body's trying to heal itself. And sometimes the body gets caught in a loop. So a herniated disc is a great example. The nucleus pulpal will squish out of the disc and it's called the annulus, the protective coating of the intervertebral disc. And it's not supposed to be on the outside. And once it's on the outside, the body freaks out and sends in everything. And that's why the initial injury hurts. And then two days later, you're like, good God, I'm really in a lot of pain.

10:41It's because of that inflammatory process. Your body's trying to wall it off, control it, contain it, and heal it. But sometimes people's systems go berserk and it's a horrible mess. And that horrible mess can actually damage the tissues worse. And so we are trying to get in there with something that's going to be anti-inflammatory healing and abate that pathological process and like slow the roll, if you will. And that's where I think peptides really shine. And so we have a variety of different peptides. In November, I believe it was, of 2023, all of a sudden there was a meeting at the FDA that, and I know people that usually are in on these meetings, and they told me like pretty secret meeting just happened.

11:20And many of those peptides got wiped. For those of us who are licensed, we can only prescribe them. So I can only speak to the ones I'm still allowed to prescribe. So that's what I'm going to ask you. So a lot of them you can't even get in California anymore, but you can get them in other states. Well, prescription versions I'm not sure about. And I know that there are places that sell peptides online still, and I can't speak to those because they're research labs for research purposes and not for human consumption. And I know that's where people are buying a lot of them. but I can't speak to that because I'm licensed to prescribe.

11:53So in Oregon, I can prescribe, there's a couple growth hormone supporting peptides that we still have left, like Tessamorlin, Sermorlin. We still have the GLP-1s available to us via prescription, via compounding pharmacies, but even those pharmacies are getting in trouble. For what? Well, other compounding pharmacies are turning on them and turning them in. It's really crazy what's happening right now. Like it's really crazy what's happening. And I'm somehow caught up in all of this. And my name seems to be circulating everywhere because I was just trying to introduce a new way of using these GLP ones that might be outside of what we know them for.

12:30That was all I was trying to get at. Like everyone's obsessed with weight loss and they've really vilified it and polarized it. And I'm over here like, okay, can we forget about that conversation for a minute? I mean, that's awesome. And I actually will support that because not without the lifestyle factors, not as a substitute, but in conjunction with adjunctively, I'm going to give a patient every tool I have available to get them on the path, right? And there are actually metabolic healing properties to these GLP ones that people don't understand. But over here, I'm like, look at this whole buffet of other impacts that I found data on.