Mathew Knowles: Champions Health Awareness and Living With Purpose

19 Aug 2025 · 30 min · 12 chapters

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In short

Matthew Knowles discusses living with purpose, building global brands, staying relevant as technology and culture change, and the importance of men’s cancer prevention and early detection after his male breast cancer diagnosis.

Guest backgrounds

Matthew Knowles is a third-generation entrepreneur and later a professor (20+ years) working with young people. He previously spent 20 years in diagnostic imaging, sold radiography (1980–1988), became the first Black seller of MRI/CT scanners in America, and ended his career as a neurosurgical specialist at Johnson & Johnson. He is a male breast cancer survivor and promotes health awareness.

Key claims

“Because” is passion; branding is what you communicate through optics; marketing can be simplified to who/what/why/where; greatness requires work ethic and consistency; cancer outcomes improve with early detection and genetic testing.

Notable examples

Destiny’s Child/Beyoncé female-empowerment branding (Independent Woman, Bills Bills Bills, Girls Girls Girls); Kobe Bryant’s 6-6-6 training; his family prostate cancer history (grandfather and multiple uncles); getting proactive prostate evaluation and attending a Touch for Life panel at Martha’s Vineyard.

Written by AI. May contain mistakes. Listen to the episode to check what was said.

Chapters

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Exploring Passion and Purpose

0:32 to 2:32

Matthew Knowles discusses his passion and purpose in life and work.

“That was very warm and very warm and thoughtful of you.”

Reflecting on Fisk University

2:32 to 4:24

Knowles shares memories from his time at Fisk University and his accomplishments.

“And I'm grateful that at this point in my life that I can make that decision that maybe some can't that are younger if I want to do something or not.”

The Importance of Early Detection

4:24 to 8:00

Knowles emphasizes the significance of early cancer detection and health awareness.

“You don't look a day over 25 still, though.”

Understanding Genetic Health Risks

8:00 to 10:40

Discussion on the importance of genetic testing and personal health history.

“So please, those of you listening, please, early detection is the key.”

Entrepreneurship and Adaptability

10:40 to 14:00

Knowles reflects on his entrepreneurial journey and staying relevant over time.

“Knowles, again, you've been a blueprint for me.”

The Importance of Staying Relevant

14:00 to 15:00

Learn why adaptability is crucial for entrepreneurs and leaders to thrive.

“But as I got older, I started realizing, wait, I know more.”

Understanding Personal Branding

15:00 to 17:45

Discover why seeing yourself as a brand is essential in business and life.

“for you as an entrepreneur, as a leader?”

Passion and Work Ethic

17:45 to 21:05

Explore the relationship between passion, work ethic, and achieving greatness.

“But what was the brand development that went into making you be aware that I want a pair of Jordans?”

The Role of Consistency in Leadership

21:05 to 24:49

Understand how consistency shapes trust and integrity in leadership roles.

“and eliminating till you get to three, eliminating till you get to that one thing that you love and you want to do in life.”

Proactive Health Awareness

24:49 to 26:55

Learn about the importance of preventive health measures and community involvement.

“And in my first book, I have a chapter called Talk to Do Ratio.”
Show all 12 chapters

Upcoming Events and Community Engagement

26:55 to 28:04

Hear about upcoming events and the significance of community health discussions.

“experts and and folks who have gone through the experience as well like myself or cancer talking about health and wellness for Black folks.”

Gratitude and Influence

28:04 to 28:54

Mick expresses deep gratitude to Matthew Knowles for his influence and support.

“Knowles, I just thank you for being the icon that you are, for being the voice that you are.”
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Transcript

Automatic transcript. May contain errors.

0:00Ladies and gentlemen, if you ever wanted to know how to spot raw talent before the world even sees it, how to turn talent into a global brand, and how to lead when pressure is at its peak, then this episode is for you. I'm sitting down with Mr. Matthew Knowles, and we talk about the strategy behind Destiny's Child, the mindset that keeps leaders relevant, and the life lessons from surviving cancer. This is a rare, unfiltered look into the mind of a true visionary. Ladies and gentlemen, I present Mr. Matthew Knowles. Mr. Knowles, how are you doing today, sir? I'm doing great, Mick. Thank you for the introduction.

0:36That was very warm and very warm and thoughtful of you. So thank you for that. You know, I was telling you offline, there's several men that have shaped my life with you being one of them, between Les Brown, Damon John, Robert Irvine, and Matthew Knowles. I always tell myself, if I can take pieces of those men, I can be the best that I can be. And you've been the blueprint, not just for me, but for several people for so long. So on behalf of people that you don't know, Mr. Knowles, I'm saying thank you. Well, you know, as you get older, you don't realize. And then you start to realize how many people and lives that you've touched along the way.

1:20And I'm at this pathway of my life. It's really just a good feeling to know that you've made a mark in some kind of way. So again, thank you. You totally have. And Mr. Knowles, on the show, I like to ask, what's your because? That thing that's deeper than your why, that true passion that you have, that thing that makes you continue to do the amazing things that you, Mr. Knowles, do. So if I were to say, what's your because? What's your purpose? Why do you keep doing and giving the way that you do? Well, I think you said it, Nick. You actually said the because. For me, it is the passion. That is the thing that wakes me up in the morning and excites me.

2:06And I go to bed at night thinking about it. Every time I do a speaking engagement, it looks easy. You go on the stage 30, 40 minutes. but I might spend two, three days of research. And I do it because I love it that much. And I want to make sure I do my very best. So for me, the because is the passion. That's why I do it. And I'm grateful that at this point in my life that I can make that decision that maybe some can't that are younger if I want to do something or not. and that's the defining for me is am I passionate about doing it? When did you realize that you had that theme, right? So, you know, I'm going to go back to Fisk University.

2:59One of my really good friends, Kenny Anderson, was the head basketball coach there for several years. And so I go on campus and I see Matthew Knowles and I had no idea that you were a Fisk graduate, right? So when you were at Fisk, the things that you've accomplished in your life, the amazing things and the wisdom that you pour into people, did you know it then? Well, it's interesting that you bring up Fisk because I was literally on Wednesday. I had breakfast in Houston. I had lunch in Nashville. And I had dinner in Laguna Niguel, California. All in one day. And so I was actually in Nashville and and was going over the Vanderbilt and had some time and actually went to Fisk and actually went on the campus and actually went to the gym.

3:56And I wanted to just and I took a photo and I wanted to just relive in my mind. You know, we won two championships, SIEC championships, play basketball there. And I got to meet the new basketball coach, the new female basketball coach. So it was a wonderful feeling just to go back. It's been 50 years since I graduated. Wow. Wow. You don't look a day over 25 still, though. I'm going to give it to you. Thank you. Thank you. You know, Mr. Knowles, one of the things that I adore about you is your resiliency. and you've been very open about, you know, being a recoverer of male breast cancer and you do so much around health awareness.

4:49Why is it important for men? And I'm going to talk to men first with the egos that we have. Why is it so important to put the egos aside and to get the regular checkups that we need? I think, and that's an extremely good question, Mick, it baffles me often with men and women, especially those of color. Icon, most people don't realize I did 20 years of diagnostic imaging in my corporate life. I sold zero radiography in 1980 through 1988, which was the leading modality at that time for breast cancer detection. And every mountaintop, I could yell early detection. Then I went to Phillips Medical System and became the first black to sell MRI CT scanners in America.

5:44And then I ended my career with Johnson & Johnson as a neurosurgical specialist. So that's my background. and I've always talked about early detection. And the thing that really baffles me, when you look at the stages of cancer, stage, you know, one, two, three, four. Fortunately, I was diagnosed at stage 1A. But unfortunately, those who wait, those who don't Just do a simple blood test for a PSA for men or a simple mammogram that might give you 30 seconds of distress that can determine if you're going to be in one of those stages or if you're at risk. And I've seen both stages, stage one and four.

6:35If you can prevent from being in stage four and chemotherapy therapy and all the pain that goes with that and the challenges for your family and caretakers. why would you ever do that for something that could take 30 minutes or two hours of your day with parking and to go take one of those tests one in eight men in our lives lifetimes will come down with prostate cancer we'll be diagnosed with that one in eight women in their lifetime one in eight will be diagnosed with breast cancer. So I don't understand. And the more and more you give those platforms to us, like right now, so those listeners can see and hear.

7:26I don't think they maybe put that in their evaluation when they say, we don't want to do it. But the second reason I think it is, cultural conditioning since slavery, we've been taught cultural conditioning that until it hurts, that's when we take care of it. If it's not hurting, then it's okay. That's not how cancer works. It could not hurt for a while. And it can be, when it hurt, a really short-lived outcome. So please, those of you listening, please, early detection is the key. And from your viewpoint, is it an annual checkup that we should be doing when we get to a certain age? Should we be doing it twice a year?

8:19From your viewpoint, how often should we be getting these checkups? Well, from my own personal experience of having male breast cancer, for me now that I've really thoroughly researched and understand genetics. It really starts with getting a genetic test, understanding your family history. Like for example, my grandfather died of prostate cancer. Four of my dad's five brothers died of prostate cancer and his only living brother has prostate cancer. So I'm at risk. But getting a genetic test early, I'm saying now in your 20s and 30s to see how at risk you are. And then if you see that you are at risk, then routinely, annually, getting those simple exams, they're so simple.

9:15They're so simple and easy to do. See, now you just have me, I'm going to go do something. I've never had a genetic test, right? I'm going to now because you're right. It's so important because you can test for things, but if you don't know the why behind the why, the because around your health and wellness, then you're still kind of shooting in the dark a little bit, right? Like you're still kind of getting generic responses versus, Hey Mick, this is your genetic history. These are the things that we can do now from a prevention standpoint. Like the light bulb just went off for me. And I thank you for that.

9:53So for all the viewers and listeners, like please understand your genetic history is vitally important because Mr. Knowles just told us so. And just so our viewers know, our listeners, because we get a fighting for pain, I get it. It's a, it's a saliva swab. It doesn't hurt. It's a saliva swab. So, you know, we don't want to say it, but I think a lot of guys out there that think they're tough, we're scared of needles. And nobody wants to say it. So I'm going to say it out loud. I think a lot of brothers are scared of needles. And I want to say it. Yeah. Yeah. No, the saliva test, I get it. So everybody, you can go do that.

10:37You don't have to prep for it. We can all do that. We can all do that. You know, Mr. Knowles, again, you've been a blueprint for me. you've been one of my core fours, I call it, when I have your guys' name on my wall. And I literally mean that. I'm going to take a picture and send it to you so I'm not messing with you. You have a keen eye for talent. And I'm not even talking music. What you've done musically stands the test of time. But what you do for brands, what you do in the sales arena, Like that, that keen eye that you have, when did that start? Like when, when I don't want to say, when did you know, but like, when did you know that doggone it, I'm Matthew Knowles.

11:23I got it. Well, I was fortunate. Mick, no, I'm third generation entrepreneur. I saw my grandfather in Marion, Alabama with 200 acres of land. I saw this man from a genius perspective, leased off 50 acres of that land to the city there in a paper mill. And what does paper mill need? Needs trees. So they would cut off all the bush and trees to make paper. And I saw my grandfather go behind him and farm. That was super genius. They paid him to clear his land off so he could farm. My dad was a truck driver, but he convinced the people he worked for to let him use his truck all the time. And he would go tear down houses and he would sell the wood, the copper, the aluminum.

12:22He would buy old cars and sell all the parts. He would make 10 times what he was making, working. My mom was a colored maid who made$3 a day. She convinced that white woman and her friends to give all the hand-me-downs, all the hand-me-downs. And on the weekend, I saw my mother and her two best friends, because they used to make me three at the needle as they were getting older. I saw them make these beautiful quilts, made 10 times more than she made. So I got to grow up in that kind of environment of creativity and thinking outside of the box. So to have that, again, that genetic in a different way, to see my parents and their entrepreneurship, that's what was still in the back of my head growing up.

13:15that I can do this, be motivated by my parents, that I could be the best that I could be. Getting encyclopedias when they didn't have a lot of money, but taught me to research, research, knowledge, its power. All of those things is what I think are my tool kit. So we have that in common. One, my grandfather was, I'm going to say a sharecropper. My grandfather was also like the first black sheriff in our hometown. My grandfather was the first black everything, but he didn't want to be defined as being the first black. He said, because if you define me as that, then you're saying that that's the only reason I accomplished what I did.

13:55But also in my household were the encyclopedias. And so as a kid, I was I knew things that maybe I shouldn't have known or I couldn't connect dots at that time. But as I got older, I started realizing, wait, I know more. I've seen more and I'm able to do that. So one, just hearing you say that is awesome. And the other thing that I respect the most about Matthew Knowles is this, and I'm going to look you in your eye as I say this. You are always the most relevant person that I know, meaning as generations and society changes, you always adapt and evolve. And there are a lot of people, and I know that you're going to know what I'm saying by this.

14:39They can do what they do in the generation they were in, but as things change, they don't adapt. Their message doesn't relate to whatever's going on now. You stay so relevant. I think that's one of your most genius points is just staying relevant. Why is that important for you as an entrepreneur, as a leader? Well, you have to stay relevant. The world is changing every day, every second now with technology. And you heard me tell my background in corporate, it was technology. So in technology, you have to evolve and modify because technology changes by the hour. So I think the second reason, Mick, is because I work as a professor now 20 plus years around young people.

15:33and I think that really helps me to stay relevant. I remember years ago, I was at Texas Southern University in one of my classes and one of my students said, you know, Professor Knowles, you have a lot of material in that suit. I was like, well, what do you mean by that, son? He's like, you know, it's kind of baggy. That's not what's hip now. so i i get the benefit of being around you know gen z and understanding their behavior but again it's just that thirst for knowledge uh i've always been curious i've always wanted to know why in my and i've always wanted to think outside of the box and not be a box-in thinker somebody that's been conditioned and told this is a way we have to do it.

16:29And you never say, well, why do we do it that way? I'll try another way. Yeah. Yeah. You know, I have something written down that I heard you say a long time ago and I didn't get it until I became an entrepreneur. I heard it in my early twenties and it's, it's more relevant and impactful for me now as an entrepreneur and leader than it was then. You, you, I think were the first person that said you are a brand and your brand speaks for you when words can't be said. And when I heard you say that again, I was probably, I was just graduating college. I was 21 and I got it, but I didn't get it until 10 years later when I started my first business or seven years later, can you tell the listeners and viewers why it is so important, one, to see yourself as a brand, and if you're a business, to focus on the brand because it does speak for you when words can't be said.

17:31Yeah, we are all individually, as well as in our corporate careers, as well as in entrepreneurship. We are a brand. The moment we walk outside the door, we're messaging to the world sometimes without words often without words is how we look we call it the optics always the optics what are the optics you know and so you have to understand how to build a brand and messaging and brand development there's a reason why someone goes and gets a pair of Jordans versus going to Walmart and getting a pair of sneakers. They're all sneakers. They're both sneakers. But what was the brand development that went into making you be aware that I want a pair of Jordans?

18:26You know, you see, I always talk about entrepreneurship as to who, the what, the why, the where. Who is my customer? What is my product? Why should they buy it? That becomes the marketing and branding. And then the where is the distribution channels. I don't make it complicated. A lot of people making folks and professors make it complicated. It's as simple as the who, the what, the why, the where. And that's why that branding, when we went into the music industry, they were selling records. I was building brands. That's why I partnered with L 'Oreal and Destiny's Child and Beyonce to put their music and to put them in those commercials.

19:13Because the target market that we learn in marketing, finding our target market, were those women. See, people didn't understand that those songs by Destiny's Child, Independent Woman, Bills, Bills, Bills, Girls, Girls, Girls, strategically were empowerment songs, female empowerment songs. That was part of the branding and marketing, female empowerment. And even if you look fast forward into Beyonce's career, female empowerment. You look at Solange, she's branding blackness. Yeah. Yeah. Unapologetically black. So you have to understand branding and marketing is a really powerful tool. Yeah. Where do you think, we'll go individuals.

20:07Where do you think people are going wrong? Where are they missing the mark? Because you broke it down so simply. If I'm an entrepreneur and I'm watching or listening to this and it's like, I got it. Mr. Knowles is saying, I need to focus on brand. What are they doing wrong that they could easily fix? Well, I think today there's so much information out there at your fingertips. I mean, it just requires, again, going back to that simplicity of why I wrote the DNA of achievers, the 10 traits of highly professionals that really have been successful. And it starts again every time with a passion. Like, is this really what you want in life?

20:56Is this really what you want in your profession? and sitting down and taking a piece of paper and writing down 10 things you love and eliminating till you get to three, eliminating till you get to that one thing that you love and you want to do in life. Because when you live your passion, you never work. You don't work when you live your passion. You work when you have a job. When I live my passion, Like right now, I'm not working. I'm having fun. I'm enjoying this. I'm excited about this interview. But what coexists with passion, and that's where a lot of people go wrong, is our work ethics. You know, they go together like a glove.

21:45You find, I always use Kobe Bryant. After he got off the six months of the basketball season, the other players were out having fun and chilling. Kobe was in the gym getting up at four o 'clock in the morning so he could spend time with his family still. But he was doing this model called 6-6-6. Six months after the season, he practiced six hours a day, six times a week. And that's what it takes for greatness. A lot of people are okay with just being good or average. But there's some of us that strive for greatness and those work ethics and the 10 ,000 hours that Malcolm Gladwell, the brother from Canada, talks about in Outliers.

22:3810 ,000 hours that it takes to be great. Trust me, Beyonce's put in 10 ,000. Trust me, Michael. Jordan put in 10 ,000. I can go on and on, Serena and Venus. I can go on and on, the people that are great at it. because they love him. Yes, sir. Yes, sir. And another one of your pillars that you taught me to go along with work ethic is consistency, right? And when I speak with leaders, I talk about this trait more than anything is how important consistency is to everything. Because when I can see your consistency, it tells me your actual core values, right? I can see your commitment. I can see your integrity.

23:22I know I can trust you. So what do you think about that? One, you taught me that, but why is consistency also important for leaders, for entrepreneurs, for entertainers? Well, in order to move the needle, you're going to have to say it, do it over and over and over and over and over. You can't move the needle with just saying it a few times or doing it a few times or displaying it a few times. You have to consistently mean constantly doing that thing, constantly, and doing it at a high level constantly. Yes, sir. You know, everything has to be thought out. You know, it's just a lot of moving parts.

24:09I take the music industry, for example. There's probably, you know, you've got 50, 60 moving parts that all we see as artists on stage, we don't see how they got there. Yeah. And what was required to get there, the planning that was required, the team that was required. And again, going back to passion and work ethics. Yes, sir. Yes, sir. And I know one of your passions, one of the things that you're really proud of, the work that you do with the Global Brand or with the Zero Prostate Cancer and everything that you do in there, being a Global Brand ambassador. Talk to us about the work that you're doing and that that community is doing.

24:54So that's why I was in Nashville. You know, I'm very transparent. And in my first book, I have a chapter called Talk to Do Ratio. Talk to do ratio. That goes back to that consistency thing. So I was in Nashville because there's a young black man at Vanderbilt who is a genius in his early 50s in urology. And I wanted to get a consultation with him regarding my own prostate issues. Fortunately, I don't have cancer today, but I'm being proactive instead of reactive. And I said to my physician in Houston, I think you're waiting for this to happen. I don't want to do that. I want to be preventative that it never happens.

25:57Yes, sir. So that's why I was in Nashville, to be preventative, to get others' opinion, to get an expert opinion. There you go. There you go. I love it. So, Mr. Knowles, I'd love to give you just a little bit of time to talk about the great things you have going on this week. I know you're going to be in Martha's Vineyard, but talk to the viewers and listeners about what you have going on there. Well, I'm excited because I've never been to Martha's Vineyard. My wife has been many times. So she's quite excited also about coming. But I'll be there on Wednesday, August 20th. That's Wednesday of next week.

26:39there's a discussion and panel that's being given by touch for life and uh it's three o 'clock starts at three o 'clock in the afternoon uh so some of the best minds in medicine and cancer experts and and folks who have gone through the experience as well like myself or cancer talking about health and wellness for Black folks. And so I'm really excited about Touch for Life and how we can touch someone and save their life. That's awesome. I'm going to make sure that I have links for Touch for Life, links for everything that you're associated with in the show notes and descriptions. If you are a fan of me, I need you to do me a favor.

27:32I need you to not just support Mr. Knowles, and I'm not talking about financially, but I'm talking about helping spread the awareness for all the things that he's doing. I'm talking about some of the books that he has written are going to change your life because they've changed mine. If there's someone who stands for professionalism, for equality, for brand building, for the modern leader like myself, it is Mr. Matthew Knowles. And Mr. Knowles, I just thank you for being the icon that you are, for being the voice that you are. But for more importantly, for me personally, being that shoulder that I could stand on.

28:15Because there were times that I needed it. And every time you were there, whether you knew it or not, you've been that shoulder that I proudly stand on. So I personally want to thank you, sir. Mick, I can tell you have a good heart. And I thank you for that. It means you got some great parents somewhere in that DNA. Yes, sir. Great parents, great grandparents. Raised in the South, so you already know what that means. And again, you being that person that I could look to, I could never thank you enough, but I just want you to know that a big part of who I am is because of you. Well, thank you, Mick.

28:54And if any of you like to know more, just simply go to MatthewKnowles.com. MatthewKnowles.com. We'll have that link there. Everybody, please do that. Again, Mr. Knowles, thank you so much for your time. For all the viewers and listeners, remember your because is your superpower. Go Unleashing.

29:14Mathew Knowles:Thanks for tuning in to this episode of Mick Unplugged. If today hits you hard, then imagine what's next. Be sure to subscribe, rate, and share this with someone who needs it. And most of all, make a plan and take action because the next level is already waiting for you. Have a question or insight to share? Send us an email to hello at mickunplugged.com. Until next time, ask yourself how you can step up.

From the publisher

Mathew Knowles is a visionary entrepreneur, renowned music executive, and esteemed educator best known for his instrumental role in launching and managing the careers of Destiny's Child and Beyoncé. As a third-generation entrepreneur with a background in corporate diagnostic imaging and technology sales, Mathew's expertise spans talent development, global brand building, and health advocacy. A passionate advocate for wellness and cancer prevention—himself a male breast cancer survivor—he champions early detection and genetic awareness, while consistently empowering others with his decades of experience, adaptability, and commitment to leadership and education.

Takeaways:

  • The Power of Passion and Consistency: Mathew credits his enduring success to a relentless passion for his work, emphasizing that passion—paired with strong work ethic and consistency—fuels greatness and allows leaders to stay relevant across changing times and industries.

  • The Importance of Early Detection: Drawing from his cancer survivor journey and background in diagnostic imaging, Mathew underscores the lifesaving value of early health screenings and genetic testing, especially within communities of color, advocating for a proactive approach over a reactive one.

  • Brand Building Beyond the Surface: Mathew details his branding philosophy, explaining that both individuals and businesses must see themselves as brands, and that successful brands convey their value not just through words but through optics, actions, and strategic messaging.

Sound Bites:

“We are all individually as well as in our corporate careers as well as in entrepreneurship, we are a brand. The moment we walk outside the door, we're messaging to the world.”

“Passion and work ethics go together like a glove. When you live your passion, you never work—you work when you have a job.”

“Early detection is the key. For something that could take 30 minutes or two hours of your day…it can determine if you're going to be in one of those stages or if you're at risk.”


Connect & Discover Mathew:

Event Link: Touch4Life

Instagram: https://www.instagram.com/mrmathewknowles/?hl=en

Website: https://www.mathewknowles.com/

X: https://x.com/mathewknowles?lang=en

Facebook: https://www.facebook.com/mrmathewknowles/


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