Your Exponential Age

26:51I'm saying you want to keep your blood sugar in a certain range. And so if you're keeping your blood sugar in a range of say, and this is probably where people are really going to freak out because everyone's going to disagree on this. But I feel very confident in saying if you keep your blood sugar between 65, which some people are going to say is too low, but I feel very comfortable there to 85, you're loving life. If you spike occasionally up to 100, 110, all good, as long as it's coming back down relatively quickly, which by the way, the rate at which your body is able to return to your homeostatic state tells you a lot about the health of your system.

27:27So this is why they do a glucose challenge when you go to the doctor to figure out how you're doing. If I take a big bolus of sugar, my blood glucose is going to come down relatively quickly because I'm very insulin sensitive. So let me finish that thought about insulin. So you eat this sugar, it turns into glucose in your bloodstream. To a certain point, that's great. But as it starts to elevate, this is problematic. So now your body pumps, It secretes insulin, which by the way, your body will start producing insulin preparatorially. Even when you like look at the food that you're going to eat, I'm going to eat that sweet thing.

28:04You smell that. It hits your mouth. Like all of these things trigger the beginning of the glucose response, which is why there's debate around how much artificial sweeteners can actually create issues. So you have this insulin response to get that amount of sugar back out of the bloodstream. and the way that it gets it out of the bloodstream is it shuttles it into the fat cells. Now on the fat cells, there are receptors for insulin. So it's like, hey, word, we're here. Like if you need us to hold that insulin, we got you. And so you take that glucose out, which is a tremendous source of energy, which is why it's useful, right?

28:41Because if you can get glucose, your muscles can uptake it, the brain can uptake it. You can use it really efficiently. The problem is it can overwhelm the system. So you shuttle it into the fat cells. Now, the reason you have to get it out of the bloodstream is that sugar molecules, glucose molecules are sticky. And so if something bumps into it, it will stick to it. And this is where you get into the problem. So if you've ever heard of testing your HA1C levels, this is like the average level of blood sugar over, I forget the period of time, one month, three months, somewhere in there. So it's like, like me, if your daily average is like 85, okay, you're probably going to have a reasonable level when it comes to that.

29:25But if that level starts getting elevated, what that's saying is that your tissues are getting glycated. What that means is sugar sticking to it. And so as it sticks to it, now you're in trouble because it's gummy. It begins to stick to things that it's not supposed to stick to. It doesn't function well within the system. That's part of why the body's like, yo, we can't let these levels get too high because this is going to start sticking to things. and just gumming up the works. So it pulls it out by using insulin to shuttle it into either the muscles, depending on if they're being used or into the fat cells.

29:55Now, what ends up happening in a modern context is you're taking in so much sugar that the fat cells are like, yo, calm down. And so what they do is they begin stripping the sensors off of the surface of the fat cells so that it's just not grabbing, the insulin has nowhere to stick. And so now insulin's like, yo, we can't find these receptors, pump more insulin to get this stuff out of the system. And so you start getting what they call insulin resistance. Insulin resistance is the beginning of the end. If you have, it's what we would call metabolic disease. When you have metabolic disease, you cannot actively get the blood sugar, the sugar out of the bloodstream.

30:35This is where you start getting real physical damage. This is why people start going blind, why diabetics go blind, because you're literally the easy, the layman's way. And let me be very clear that I am a layman. I am not a doctor, nor do I play one on TV. I've just talked to a lot of people that know about this. What ends up happening is you're basically burning alive from the inside. So the sugar begins to damage cells. So it damages the optic nerve, which is why you go blind. It will damage the nerve nerves in your feet and extremities, which is why people get neuropathy. They don't even feel that their feet and toes and legs are dying and they end up having to get amputated.

31:16And this is all just from having too much glucose in your bloodstream. And glucose is just, it is what sugar turns into. It is what carbohydrate turns into in your body. And so people have to get really good at understanding that if something says that it's carbohydrate and not fiber-based carbohydrate, that is going to be glucose in your body. So people think that they get away with stuff with a lot of things that they eat and drink that they don't realize just because it doesn't say sugar doesn't mean that it isn't sugar as far as your body's concerned so people have to get real thoughtful so anyway you're gumming up the system you're spiking your inflammation it is going to one make performance difficult your joints are going to hurt uh you're almost certainly going to start spilling into brain fog you're definitely going to get into the realm of autoimmune disease and now your body's attacking itself.

32:03And that's where the real hell begins. And so just to catch people up is a lot of people think, well, I'm going to run out of energy if I don't eat sugar or carbohydrates. And people need to understand ketosis and the use of ketones and how our body actually is very efficient. It's got dual engines, like a petrol engine or an EV. And it can use two different ways of using fuel. So if you could just explain what fuel you're burning if you're not burning sugar, because most people just think energy, sugar, oh, I feel better now. But you're not doing that, which is a much more even fuel supply. Yeah.

32:38So I think most people, you want ultimately what they call a flexible metabolism. You want to be able to burn glucose. Glucose is not bad. Glucose is necessary to your survival. There are regions of your brain that cannot use ketones. So no one is going to get away without having glucose, but the body's prepared for that. So there's something called gluconeogenesis. So the body can actually take protein for sure. I think it can even do fat, but I think it's hyper inefficient. So about the time that your body's trying to turn fat into glucose, you've really got a problem, but it will certainly turn muscle into glucose.

33:16It can turn protein, dietary protein into glucose. So this is why they, I have a hypothesis. I should be very clear about where I'm at the edge of what I understand. I am now at the edge of what I understand, but I have a hypothesis that part of the reason that muscle mass is so linked to all cause mortality, meaning the higher your muscle mass, the lower your likelihood of dying from all cause mortality. Why would that be? Because it's a repository of amino acids, which are building blocks for the body. And that is how you can actually metabolize that muscle and turn it into sugar, glucose, if that's what you need in that moment.

33:55So you're going to need some. So just let everybody be very clear. This is not a game of getting your glucose to zero. If you do that, the prize that you win is death. So you play stupid games, win stupid prizes. So we do want to be thoughtful about that. What you're talking about with ketosis is really fascinating. So to have flexible metabolism, what you're doing is saying, hey, body, sometimes you're going to have glucose. Go ahead and burn that. Other times you're going to have ketones. go ahead and burn that. What ketones are is the byproduct of fat metabolism. So this was the moment where I was like, oh my God, of course.

34:34Ask yourself this question. Why does, if glucose is such a wonderful source of energy, why does the body store that as fat? And the reason it stores that as fat is it's a far more stable way to store that energy across time. Okay, cool. But if the body is going to say, this is my stable way of storing this energy across time, then it has to have a way of getting that back into the system and utilizing it. And the way that it does it is through ketosis. And most of the ketones are produced in your liver. So your liver sends a signal, hey, we're going to need some ketones. Boom, it releases the fat that it's going to need.

35:14And this is basically what dieting is. You're telling your body, I'm going to need to release this fat to get it turned into ketones so that it can be used in the body for fuel. Now, most places in the body can use ketones, some can't, but most places in the body can. So you get ultra endurance athletes that are all ketogenic, their primary fuel source is ketones, and they're setting world records and absolutely smashing it. Some people love to perform that way, other people swear by a more carb centric diet. This is why you get into N of one, right? So you're going to need to test the stuff, what works better for you?

35:45What do you like? Just a quick moment to remind you, today's Real Vision Daily Briefing is sponsored by CraneShares. Learn about their KRBN ETF at craneshares.com forward slash KRBN. Now back to today's analysis. What I will say is nothing is universal. And there are some people that have a really negative cholesterol response to the ketogenic diet. So do the stuff with your eyes wide open, make sure you know how your body is responding. But ketogenics is the closest thing to a specialty diet that I think everybody should at least try. Now, the reason I think you should try it is because it's the only thing I know of that will fundamentally change your relationship to two things, hunger and inflammation.

36:38So for 15 years, I iced my wrists every day. I had what I thought were permanent burn marks just because I was icing them so much, just because I had inflammation. I've had inflammation since I was in my early 20s. So I just thought, I don't know why, but I've always been super inflammatory. Like when I was a kid in school, you could scratch attach a word into my arm, and it would stay with a welt, just because I welted up. My dad was the same, kind of thought it was funny, to be honest, not realizing, hey, this is a warning sign that you're going to die early. So I was like, ooh, once I realized that inflammation is a sign that the body's really having a hard time, there is a problem somewhere, and you need to address it very, very quickly.

37:22So this is during the quest years, and meet a guy, two guys, actually, Peter Atiyah and Dom D 'Agostino. And at that time, I still believe fat is bad. So I'm doing the rabbit starvation. And I'm getting lean. So I think I'm doing everything right. And I've always been inflamed. So I didn't think about it. And they come in and they're like, you sir are killing yourself. You must immediately get high quality fast into your diet. There's this new thing called ketogenics, you should really give it a shot. And they described this diet. And I was like, there's no way I will be dead by the end of the study.

37:55And they're like, it just isn't true. You need to give this a shot. And so I started eating high fat. So for anybody that doesn't know the ketogenic diet, there's a very simple way to explain it, which is that there is a blood marker, which is a ketone. You can test for it. And if you get your ketones to 0.5 millimolars or higher, you're in ketosis. If it's lower than that, you're not in ketosis. Now, there are certain things you're going to need to do to get your body to start producing ketones. There is a reason that people refer to this diet, a ketogenic diet, as a fasting mimicking diet. So you're going to eat something that tells your body, whoa, I'm not getting any calories, even though you are getting calories.

38:38And that dear body, you're going to need to switch over and burn fat. So you're going to eat a ton of fat. Now, in the beginning, what I did was a four to one ratio, meaning for every combined gram of protein and carbohydrate that I ate, I ate four grams of fat. What did you anchor your carbs on? I always use 20 grams as my maximum limit. That is roughly where I settle out. If I keep my daily carbohydrate intake around 20 to 30 grams, depending on how long I fast, I can stay in ketosis. Or I might dip out at some point in the day and then get quickly back in. People will start to learn their body.

39:22You can feel it when you click over into ketosis. It's really bizarre. So yeah, at that time, I was anchoring probably on the low end of that 20 ish, 15, if I could sneak it in. And so your food is disgusting. It's just fat. Like imagine just eating fat, like straight olive oil, heavy cream, the fattiest nuts you can find. It was miserable. I hated it. Absolutely hated it. So while I'm doing this? I'm thinking, I'm doing this to try and live forever. Oh God. But what I noticed was my wrist feel perfect. And you can imagine after 15 years of icing them every day, having burn marks on the back of your hands from icing them so much, I was like, what is going on?

40:07And so I was like, wow, this, I, cause I was testing it as a part of it's the exploration that people were doing around its anti-cancer properties. So I wasn't even thinking about inflammation wasn't on my radar. But that I was like, I remember saying to my wife, this is life changing. And so I'm never going to take fat out of my diet. Now, I didn't enjoy four to one and I wasn't doing it well anyway. And so I went through something that people call the keto flu, which you can supplement your way out of. You don't have to make all the mistakes that I made. So then I figured out how to do it well.

40:38And I ended up doing it for nine months. and that really showed me that I don't need to ever feel inflamed. And so there I was by that point, I'm probably in my late 30s and I have way less inflammation than I had in my 20s. So that imbues me with, oh my God, based on what I eat, I may not be aging backwards, but I feel better than I felt when I was significantly younger. And so that gave me this sense of like, hey, these are solvable problems. like you really can optimize. And so at the height of my wrist pain, I was starting to get knee pain. And I thought, man, this is just how it happens. And now I can steer by my knees.

41:19If my knees start hurting, then I know that I've done something on my diet that I'm unaware is causing a problem. I need to figure it out. So you really do get into a new through body. So I ate ketogenically for nine months, meaning that for call it at least 80 to 85 % of the day. and I would test my blood, that my ketones would be anywhere. I usually stayed between one and say 1.5, 1.7, somewhere in there. And I could have lived like that forever. I began to have some concerns that I was not keeping on muscle mass in the way that I wanted to. And so I backed off of a strict ketogenic diet before I'm measuring it.

41:59Yeah, took my protein up. I did not take my carbohydrate intake up. In fact, the only carbohydrates during the week that I eat come from berries or vegetables. That's it. And not even root vegetables, because they've all got carbs. So I just use anything that grows above ground as a vegetable. So people are going to be listening to this going, well, yeah, this is a lot of hard work for a bit of vanity and feeling a bit better and not having swollen wrists. But actually, what we're talking about is longevity of life. even including fasting we don't fast because yeah makes us feel a bit better and it keeps us from consuming as many calories it actually has benefits all of this added together what you're talking about actually helps you live a longer healthier lifespan don't you think though that and maybe your audience really is this audience most people don't think about the future they're so in today, I find if I can get you excited about like, if you have pain, then my emotional leverage over you is I'm going to make your pain go away.

43:05Not maybe I'm going to make your pain go away. And then if you're, you know, if you've always wanted to look good in the skinny jeans, like got you covered. So longevity is like the high end thing. And now if somebody wants to talk longevity. Now, we have to go beyond that bulk of this is what works for everybody. Longevity becomes its own side question. Everything that we've talked about so far is table stakes for longevity. If you don't do it, you will never get longevity. ED HARRISON See, most people, honestly, most people think longevity is keep reasonably slim and go to the gym. And yes, but actually, diet is by far and away the biggest influence in all of this.

43:51no no doubt so if you if you said uh tom you i need you to destroy somebody's life and i'm only going to give you one tool to do it and you can mess up their sleep you can mess up their diet um you can have a personal tragedy befall them but you really have to like do damage i'm going to take the diet every time and i or anybody could you you can just destroy anybody by making them intake the wrong foods and they will stop being able to sleep. So I didn't need to mess up sleep directly. I can mess it up through their food. They're gonna be wildly inflamed brain fog. They're gonna have mood balance.

44:37Yeah, it's going to be crazy. So people have to understand that if you are staying slim because you have a natural genetic gift where like take my wife, if my wife and I have a cheat day, like really go crazy, let's say it's a special occasion, we go nuts, we have a little bit of alcohol, we have some cheap food, she will sweat so much. She's done this. She will take her shirt off in the morning and you can actually ring it and drips will come out. I don't. I just get fat. And so you can hear me getting fat. It's crazy. So we have a very different metabolic response. So some people are going to be able to stay slim, even though they're eating in a way that is 100 % destroying them from the inside.

45:23And so you may not see what's happening to your arteries, but it's happening. Because if you're elevating your glucose, whether you get fat or not, you have all that stuff gumming up the system, you're probably breaking the epithelial lining of your gut, you're creating all kinds of problems, brain fog, all of it. And so all of that stuff is chipping away at the cellular integrity of the organs in your body. And once they go, that's it.

45:56And so this sustained inflammation, plus the damage that you do without really realizing you're doing it, compounds. And what you're doing is you're trading off either the lifespan of health, your health span, or your lifespan itself. So let's talk a little bit, we're going to have to do another whole discussion on a lot of other things another time, because there's a lot here. But I just want to get into, okay, so we've got this right, why fasting? And then what are the David Sinclair style supplements that people can do that help your body compound these processes? And then I think another time we're going to go through other aspects of health, mood, sleep, all of this stuff, because I think people should be fascinated and will be fascinated by this.

46:48And you've gone down this whole journey, just go to impact theory, just see the number of videos and all of the people you've spoken to. And you're like me, you're actually being selfish because you're just learning. So you could just interview all the people in the world. But anyway, let's talk a little bit about fasting and a little bit about supplementation. And then we'll come back to this on another day, and we can talk through some more detail. Sounds perfect. So fasting, I think, is really important to developing metabolic flexibility. And so again, forcing your body into the state where it's like, I have to burn ketones because I don't have anything else.

47:22And so that metabolic flexibility is the thing I mentioned earlier that it will change your relationship to hunger. that metabolic flexibility is what changes your relationship to hunger. If you're a sugar burner, meaning you're always burning glucose, just because you never deprive your body of glucose, so it just always has it. The second you are then deprived because a meal gets pushed off by an hour, you're in a meeting, it runs long, your performance rapidly declines because your body's just screaming out for that glucose. It doesn't have it. And so people get hangry, as people talk about.

47:52So that creates where you constantly have to be worried about hunger. It's really annoying when you are hungry, your performance declines, et cetera, et cetera. So I think people should do it for that reason. But then also, you just want to give your body the ability to rest. And so when you're constantly pumping food into the system, you've got the machinery running all the time. Now, I don't hear anybody talking about that the body just only has so many cycles. And so take this as a layman's hypothesis about people, I think, maybe intentionally turning a blind eye to something. I think it is self-evident to me that your body can only do the things that it does so many times.

48:35And while that's not going to be the only factor because their external radiation is going to dramatically reduce the amount of times. It's not the age, it's the mileage. But it's like everything that you're doing is the mileage. And so this is why ultra long distance runners, they don't die old, man. So you're just putting a level of tax on the body. This is not a popular opinion. A lot of people are going to disagree with that. So I want to be very clear. And again, I'm not the scientist, but I have a feeling science will catch up to that idea. So that it's part of it, not that it's the whole thing.

49:11I am hyper aware of all the toxins and all that stuff. So giving your body a rest, we already know, has significant impacts on your day-to-day lifestyle. So take, for instance, one of the most important things you can do is get good sleep. One of the best ways to increase the quality of your sleep is to stop eating at least three hours before you go to bed. I try to eat my last meal somewhere between seven and eight hours before I go to bed. So I stop chewing usually by 2 p.m. I go to bed at nine. So that's seven hours every day where I haven't, I'll have sips of water, but I don't even drink much water after that.

49:51So my system is completely devoid of anything to process. And so I'm able to sleep well. If I eat only two or three hours before I go to bed, I do not sleep well. And I don't like the way I feel when I wake up in the morning because what's happening during sleep is your, the mobility in your digestive tract goes to zero. Like that's not what that period of time is for. And so it's just sitting there. And so that can create discomfort. It can create inflammation. It can create pretty significant problems, especially if you've eaten something that your body doesn't like. So for instance, if I'm going to really go on a bender and let's say that my wife and I are on vacation, we're celebrating something big.

50:31We want to have some cocktails, some ice cream, whatever. So I'm going to start that at noon. I'm going to be done by three. And then I'm going to be stone cold sober before I go to bed. If we did that, I'm probably going to stay up till 10 or 11. So now I'm going to have eight, nine hours of nothing but water in my system before I go to bed. And honestly, while I don't feel like I ate normally the day before, I don't feel hung over. It doesn't feel rough because I've given my body all that time while it's wide awake to process everything to be done with it before I go to bed and shut that machinery off.

51:07So you can think of it as like, hey, if you eat, you've just told your system, you have a lot of work to do. But then right as they start, you're like, but now we have to shut everything down and you need to go home and come back tomorrow. But by, you know, if you think about something, you come back tomorrow and it's sort of dried and crusty. It's like different when you wash the dishes, right? when you get them versus if you leave it till the next day, right? And that's wild, very much analogy that I think will get people to understand. So intermittent fasting lets everything take a break. It improves the quality of your sleep.

51:39And it also, there's almost certainly other effects like circadian rhythm and things like that. We're just from an ancestral period. We just would have had these certain rhythms of when we ate, when we didn't eat, that there would be these huge amount of times between when we eat and when we don't eat. And so you want to create a lifestyle that mimics that because there are almost certainly things that we don't even know about yet that are going to play into this. And so I have just found that one, fasting gives me that metabolic flexibility. Two, because I'm producing ketones, I experience hunger very differently.

52:18While I know, oh, I'm hungry, it doesn't decline my performance. That's the easiest way to say it. And then other things. It helps me re-regulate my sleep patterns. It helps me sleep well through the night, helps me feel great the next day. And then there also are studies showing that there are other benefits. I don't know the studies well enough to pop off on them, but every time I hear them, I'm like, yeah, there's just more and more evidence mounting that fasting helps. And also fasting helps repair broken proteins. And so it cleans up your body as you go. So - RAOUL PAL You're talking about autophagy, super brilliant.

52:55Yeah, please give people a breakdown on this. I think it's very important. RAOUL PAL Yeah, autophagy is the process by which that if you take out food from the body, what's happening is the body starts repairing itself. It kind of goes into this rest mode. It's like, okay, we don't need to do anything. So why don't we clean up our bedroom? So they go and clean up their bedroom and taking all the broken protein, which is the things that you have damaged via lifestyle and other things, and it cleans them all up. Now, it is proven scientifically that people who leverage autophagy, so people who have calorie-restricted diets or fast, live longer.

53:31And the reason being is all the junk in your body gets cleaned up. Much like I use my Mac Keeper to clean up my Mac now and then, clean out all the junk, it runs longer and better enough to place my computer as often. This autophagy process does that. It's magic. The body sits down and goes, right, we've got some spare time. Let's just sort our stuff out. Yeah, autophagy is maybe one of the most important things for people to understand. And this will lead us into the other thing you wanted to talk about, which is supplementation. So the reason that autophagy becomes important is that there are different states that a cell can go into.

54:08So you have a normal cell. It's dividing. Everything is going well. You then can get a senescent cell. Now, a senescent cell knows, hey, I'm dysfunctional, so I'm not going to keep dividing. but I am going to keep trying to like do my thing. The problem is that senescent cells send off inflammatory signals that cause the body to respond. So the more senescent cells you have, the more likely you are to be inflamed, which is, I think, part of the reason that people experience like vitality when they're fasting. To your point, not only are you giving the body the time to do it, but you're giving it the hormetic stress of, hey, you're starving.

54:47Nothing is coming in. It's been 18 hours. I don't have any food coming in. What the hell? So I still need my building blocks. And so there's like a hierarchy of things that the body's going to go after. So first it's going to start with these senescent cells. So, all right, everybody, thank you for stopping dividing. We really appreciate that. But now you're going to go through what's called apoptosis, which is programmed cell death. So we're going to need those parts back. And so they go in and literally, in a highly coordinated controlled fashion, They break apart the senescent cells and they take back those pieces that they're going to use now to create other healthy cells.

55:23Now, there's another process that happens with fasting called mitosis or mitophagy, excuse me. And mitophagy is the programmed cell death of mitochondria. Now, mitochondria is a whole thing, like a whole thing. I just had a guy on the show who hypothesizes that all mental illness is the result of metabolic dysfunction of the mitochondria. Utterly fascinating. Time will tell if he's correct. But he's really got a lot of internal logic that he uses to explain why he thinks that basically it's in the same way that your body begins to malfunction through metabolic disease in a way that's very predictable.

56:06We've all seen it play out with diabetic patients. He's saying this is the same phenomenon, just this is how it plays out in the brain. So very, very intriguing. But anyway, your mitochondria will go through the same thing. People think of the mitochondria as the power plant of the cell, and it is, but it's far more than that. It's a master regulator in terms of hormonal production. They actually have receptors on mitochondria for a lot of the neurotransmitters that they produce. so they can actually communicate to each other with neurotransmitters. So you can imagine if he's right, that that could be why you've got, that if you focus on metabolic health, you'll see reduction in the incident of mental health in patients.

56:53And his number one treatment for bipolar, anxiety, depression, schizophrenia. Oh, there might've been another one in there, but all of those, oh, autism, the nice and controversial. So his number one treatment for all of those is a ketogenic diet. Now he's very clear to say, it's not just a ketogenic diet. There are many factors that play into this, but if he's looking at your life, one of the first things he's going to do is get you on a ketogenic diet. But what he's actually trying to do, not like that's some secret pill, he's trying to get them a good metabolic health. He's trying to get this autophagy and mitophagy to happen.

57:32So those senescent pro-inflammatory cells get cleared out of the way. The damaged mitochondria get cleared out of the way. And now they have the building blocks to make new of both. And now you get the system running again. You also decrease the amount of glucose in the bloodstream for all the reasons that we talked about earlier. And he says just the way that that plays out in the brain is improved mental health. And so, again, anecdotally, but he's got a lot of people. This is a Harvard professor, not some fly-by-night guy. And he has turned around countless people in his private practice because he's still a clinician.

58:09And so he said he has seen turnarounds in mental health that have been absolutely startling, including people coming off of, not necessarily coming off of all their meds, because he's very careful to denote coming off psychiatric meds is very high risk, and you have to be very careful. but where people no longer need either the quantity of medicine or in some cases have been able to come off and they've completely gone into remission on things like schizophrenia, which to me was utterly shocking. But again, just all to reinforce your point about autophagy and mitophagy. So I think we're not going to do supplementation here.

58:48I think we're going to do it the next time we get together because it's a whole other topic. And I think there's a lot to digest here for people. Well, I will say we should probably do supplementation right now because I don't supplement. So I know virtually nothing about supplementation. I am super skeptical. I am not knowledgeable enough on this. I'm not the guy that you should take advice from. But man, do I urge caution, caution, caution, caution. So I think here's one man's hypothesis. When you isolate something, the odds of it having the effect that you want it to have is virtually zero.

59:25There are going to be second and third order consequences. Like for instance, hey, I can't get any sun, but no big deal. I'll just take a vitamin D three supplement, which by the way, I do if I can't get sun. That's the one thing I do supplement. But the problem is, have you thought about the fact that sunlight, literal photons from the sun penetrate so deeply in you that even if you have clothes on, it will penetrate down through into your bone. Now, does taking a D3 supplement have the same effects? My guess is no. So I don't think we know enough about supplementation to supplement. I think people are gonna get themselves into trouble.

1:00:00So I highly encourage people, you need to pay attention to the things that supplements are leading you towards. But if you have a diet, vegans, I'm looking at you, that require a lot of supplementation, odds are it's not ideal. Now, if you're doing it for moral reasons - Yeah, it's not natural. That's right. Yeah. But there was a whole school of thought, and maybe I'll get David Sinclair or one of the others on about the M &M and all of the various other parts that people are looking at, which has still been isolated mainly to animals in a lab condition. Get them on. They know so much more than me.

1:00:31But I want to be very clear. Some of the brightest minds in this space, people that I've had on my show, off camera will tell you, oh, I was taking - I'll use a supplement that I've heard directly from some of the brightest minds in the field.

1:00:49Metformin. Three years ago, Tom Metformin, it is a silver bullet, no consequences, no downside, been using it for 30 years, not a problem, 100 % you should be taking it. And I'm like, I don't do supplements. Now they're saying, hey, man, good thing you didn't take that, because now we're starting to see that there might be knock-on effects in healthy people, because all the data that we got is diabetics. And so if you're diabetic, you probably should fucking take it because you have a totally different problem. But if you're healthy, you might not want to take it because it might be blocking like the effects of exercise and things like that, the positive effects.

1:01:23So all of this stuff's a huge gamble. Now I will say the reason that I said that talking about fasting and all that will lead us into supplementation. There's one supplement right now that I am so intrigued by, and that's rapamycin. Now I don't, if we're out of time, We can stop here, and we can pick back up later with mTOR, rapamycin, all that. But this is where it gets interesting. RAOUL PAL Yeah, I think this is another whole thing that I want to go down. But we'll do it at a different time, because unfortunately, I have to go. And I just think I'm so fascinated by all of this. You've gone further down the rabbit hole, but I've been following this whole path.

1:01:57And then there's a lot more of other stuff. I think, for me, this is going to add value to people, because it gets people to understand how to live healthier, feel better. What's it all worth? You can be an investor, you can be the richest person in the world. But if you're unhealthy, miserable, depressed, mood swings, bad relationships, you haven't got a life. The actual game of life itself is living a quality of life. Everything else is second. This went by so fast, man. It was a lot of fun. So, I know. Yeah, we will do a follow-up on this, but I really enjoyed it. And thank you. Picking your brain was brilliant.

1:02:37Okay, as I said, there's a lot there. For me, this felt like it was 10 minutes. There was a lot of information. The basics of what Tom has talked about are you are what you eat. and it is the quality of what you eat and how you eat that creates all sorts of huge health benefits, not just in terms of weight, but energy and the actual cellular level of the body. And if you start thinking in this way, and it sounds like, oh my God, he's crazy. He's got glucose monitors, all of that. It's not this. There are some hacks, simple ways of thinking is your relationship with carbohydrates is a really simple one, or can I go for a while with not eating?

1:03:21These kind of things, what you eat and when you eat and how you eat, are proven scientifically to extend your health span and your lifespan. One of the reasons why the Mediterranean diet works so well, or the Okinawan diet, is based on many of these principles. I'm going to bring Tom back at some point to talk more about this, because I think this quality of life bucket is one of the most important things we don't discuss enough in Real Vision, the investment in ourselves. Anyway, I hope you found it useful. Thanks for joining us, everyone. Today's Real Vision daily briefing is sponsored by CraneShares.

1:04:01Learn about their KRBN ETF at crane shares.com forward slash K R B N.

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