Stop Disease 5 Years Early: AI + DNA Playbook With 23andMe's Founder Anne Wojcicki

22:54Marina Mogilko:But at least for a couple of weeks, like with a glucose monitor, at least you can figure out what effects. Right. And I think I love doing it like when I'm doing talks or other things or just even like, like we've had all the graduations, which has been a lot, like measuring for a period of time. Yeah. Will be interesting for people to understand, like what are those behaviors? From all the data that you're seeing, What do you think of the diseases that have the best chance of being cured or treated in a different way in the next five years? I think a couple of things. One, I'm Jewish. I find it absolutely the crazy that the Jewish community does not own the responsibility for the next generation to all have genetic testing.

23:33And the Jewish community has the higher rates of hereditary conditions and conditions like BRCA variant for breast cancer, ovarian cancer, prostate cancer. Like, why doesn't everyone know? Like, why is anyone dying of a BRCA variant? Especially when there's things that you can do. If you know you have it, you can have a prophylactic mastectomy. You can have, you know, you can have kids earlier take out your ovaries. Like, you can have more aggressive screening. Like, there's things you can do. So I look at that's one area where there just should be this is a community that should step up and have proactive testing.

24:10And no one in the next generation should be surprised. Cardiovascular, there's so many genetic variants that if you know ahead of time, you can absolutely manage them like you with familiar hypercholestremia. I've met so many people in this journey who are like, oh, I have this like really high cholesterol. And I'm like, I'm eating kale every day. And I'm like, you know, you might want the genetic test. And then you just, there's aspects that you can change and aspects where you can prevent. Like you can medicate and you can prevent. I think in cancer, hereditary cancer is one of those areas. Like we know there's a number of genetic variants that can put you at high risk.

24:49Genetic testing now is so inexpensive. And those people should never be surprised. And that's where I look at like cancer, heart disease, the Jewish community. You have all these other areas, the African-American community as well with sickle cell, a condition called TTR amyloidosis. There's chronic kidney disease. Every single person can benefit from genetic information and use that to modify and prevent disease. But I do look at like the Jewish population, African-American population, frankly, you know, cardiovascular disease and cancer. I think you should be able to have a significant like, you know, remove the the the very regrettable deaths that happened because people had a risk factor and they didn't know.

25:38Marina Mogilko:Totally. And we already saw a kid being treated with them modifying how they get processed protein. Yeah. Modifying their gene. I mean, Bob, baby KJ. Yeah. Yeah. Yeah, baby cage is amazing. How far are we from doing this to common diseases? Because I think what I've heard is that it's mostly like those genetic diseases you're born with. So you can modify a gene. Can we in five years, just if you're predisposed to breast cancer, just modify the gene? This is outside of my area. But if you look at Jennifer Doudna and people in the CRISPR field, and there's a number of experts in this. and um i sat at a conference recently with one of them and he was just like you know so passionate like every disease is genetic and we should be able to like we're at the beginning of a crisper era where you should be able to figure out like cystic fibrosis or you with familiar hypoclostremia or brocca variant like there should be a world where that's coming where you can fix that yeah We're not there yet.

26:39Okay. But baby KJ is a pretty amazing story. Yeah, it's the first sight of the future. I remember when there was the first IVF children and it was like, it was so extraordinary and now it's so common. Yeah. So I think the next 20 years will be extraordinary in that way.

26:56Marina Mogilko:Hopefully sooner as well. I was just talking to an economics professor from Stanford yesterday and he said in the next two or three years, we're going to see something dramatic that's going to happen because of AI that's going to change our lives. I'm always more hesitant in health care. Like I'm a little bit always of the Debbie Downer because like you still have to do human clinical trials. You still have the FDA. There's going to be issues like it's not going to be perfect the first time. So I always try to set expectations. Biotech's not the transformative, you know, industry that's going to like change in the next five years.

27:26I think that there's all kinds of things that are happening in the early stage of discovery. but you have to then translate out that those discoveries and those insights actually lead to drug discovery. When I was in my investing days, there was all these technologies on like high throughput chemistry and all these, you know, high throughput ways of doing biology that were important techniques, but, you know, fundamentally 90 % of drugs all fail. And it was 500 million to develop a drug back when I started. And now it's like$4 billion to develop a drug. So all right, maybe it's like 2 billion.

28:03We're not getting better is my key point. And so the only thing, the reason why 23andMe got in drug discovery is because one of the only areas that was seen to improve the outcome and the likelihood of success was starting with the human genetic insight. And so we know that starting with human genetic insight means that your drug is more likely to succeed, we don't yet know on AI how much that's going to help it. So I'm super optimistic and I love that there's all this money going to the space, but I, I, I'm always like cautious to the broad population to not overset expectations that you're going to have a radical change in the next five years.

28:43Yeah.

28:43Marina Mogilko:Just eat whatever you want. I think the radical change that you can have in the next five years is risk prediction. I think a hundred percent, you should be able to predict who's most likely to have breast cancer, colon cancer, heart disease, like 100%. And then you should allocate resources based on that. What do you think are the top three things that everyone should do after listening to this conversation in regarding to their health? Because when I was at Susan's foundation launch, I was like, okay, I need to do this pre-nouveau scan. I have done my 23andMe, then I'm going to connect all of that with AI and see what it tells me.

29:17Marina Mogilko:Do you think it's a decent decent plan i think that the most important thing um 23me has has three different products we have a product called total health total health is your exome so it's a deeper level of sequencing and it's blood everyone from a medical perspective should go and get that it's the gold standard what people want to be able to go and get better than spitting it's two products so this the dna is still spitting yeah okay but at some point you want to get your blood you want be able to understand your blood as well and so per nuvo is super interesting and i'm an investor in it i do it every year there's still like a world of people all assessing like exactly what do you do with this information and i recognize there's people who are anxious um because you'll find all kinds of things and so it's it's for people who want to embrace like i i can handle it if you go and you tell me you have like a strange lump in your uterus you're not going to freak out and that you're OK to follow up because you'll find a lot of things.

30:14And some of them, like I know lots of people who found brain tumors and heart issues and aneurysms like the stories are astounding. But you also have stories of people saying, oh, they found something and it was nothing. And I had this whole workup. That's where PreNuvo, I think, is doing a lot of work to understand exactly how you want to do an MRI. I do annual chest CTs. So a low dose chest CT is minimal radiation. I'm in a category that's genetically higher risk now because Susan had it and I do that and there's amazing AI work here where and this is part of what the Susan Wojcicki Foundation was also part of and helping to support is can you use your my chest CT to give me a five-year prediction

30:57Marina Mogilko:so when do I able to identify right so when do I want to get when do I need to get another scan Similar to a colonoscopy when you go and they say, like, do you need to come back in two years? Do you need to get back in 10 years? So it's going to be a similar kind of experience there. The other thing that's important for people to recognize is, like, health can be really stressful and triggering for some people. So some people, we get Brian Johnson, who, like, obviously loves testing everything. And I'm so grateful to him because he tests all kinds of things that I do not want to test. He's testing all of it.

31:29I get other people, like, I had dinner with someone last night who's like, I don't like getting blood. And so there's an element of choice and respect for people like people should all have. And there's people who are going to be pioneers helping to sort of pioneer what is this revolution and like what are we all learning together? And so for those people, like you're doing blood twice a year, you're doing your genetics, you're doing ProNuvo, you're doing like as many scans as you can. You're like putting all that data together. The stuff that's really validated for people is like having a baseline genetics, making sure that you're doing the core blood tests and that you're doing all of the preventative screens.

32:05That makes sense for you.

32:06Marina Mogilko:It all comes down to discipline as well, because your AI can tell you anything. But then you have to go and execute. And yes, getting those annual checkups to see how you're progressing or what's changing. And this is where I do think like aura and all these, you know, your Apple Watch are amazing at predicting changes. And even, you know, we had a friend who just had a health issue and it was amazing how Apple, the Apple Watch, you know, triggers and says like, oh, you know, you were unstable the day before. And so having those and that's what I love looking at is the patterns of like, oh, you've really been sleeping worse.

32:42Like what like what happened? And like I stopped wearing the aura ring when Susan was sick. I was like, I don't need you to go and tell me. Yeah, I'm aware. But like having the trends over time and and watching things like I'm 52 now, like understanding how my body is changing and what do I need to do? And like, am I sleeping better? It's actually nice to have data and to understand that. And I was really clear. I was like, OK, I'm going to start going to bed earlier. And I can see a difference. Like when I'm in bed reading on my phone versus I turn off social media and I just go straight to sleep and I read a paper book.

33:15I see the difference in quality. And so that's where data has helped me. Totally. Quick pause.

33:22Marina Mogilko:My team and I are celebrating one year of the Silicon Valley Girl podcast. I know the channel has existed for a while, but a year ago, I made a decision to focus on amazing conversations with people who are building our future with AI. And for a whole year, we worked to bring you the biggest founders and builders in AI so you can keep up in this era and get inspired. If you love what we're doing, please subscribe and hit the notification bell. It's what helps us bring you the biggest minds of our lifetime. Thank you so much for being here. I want to focus in this conversation as well on your mindset as a founder, because a lot of your bets, I think all of your bets, because you're doing 23andMe, I want to talk about Downtown Los Altos, you're doing Susan's Foundation, they're all long-term bets.

34:06Marina Mogilko:How does your mind function in the world where every day there's something shiny, something fancy, and all of your bets are like 10 plus years. You know, it's interesting because when I was driving up here and I was talking to some of the bankers about this SpaceX IPO, I knew Elon because of Sergey. And I remember in like the very earliest days when he was starting Tesla and he would stay with us. And he was so consistent talking about his vision of like Tesla and the space world and the potential. I have to say, like, it's complete kudos of like, when you think of like long term vision, the world and I look at all around us, like everything that's happened today, to make significant changes in the world, you have to have a long term vision.

34:57And you have to be so consistent and maniacal about doing that. And you have to also love what you do. and that's where like I look at again I talk ad nauseum about like how much I love genetics and but I do again it just occurred to me thinking this morning is like people who love what they do you have a long-term vision and you're consistent with it and it never feels like work and and every single day builds on the previous days and so I look at 23andMe every single day I walk into the office and I'm fascinated by the research that we can do. Like what motivates me every day is this idea of when I'm helping people, like I always wanted to be a doctor, but I feel like now I'd like I help more people because I help connect on identity.

35:45I help connect on family connections, like reuniting all these people and we save lives. Like I give people valuable information about themselves um and then the research is like i mean for me it's again my dad who loved neutrinos like and he loves space and all that like i was like hey you like looking up in the sky and i like looking inner i like find that there's an entire universe in every cell we understand nothing about it like even i was with somebody talking about like the beauty of the mitochondria and like that you have this like power engine and how it works like we understand and so little.

36:24And that's what I love. Like every day, it's like little tiny bricks coming together to build this foundation of knowledge. And it's so interesting. And again, that's what like, I always advise kids, like whatever you do, like make it. So every day you have like that spark of joy where you're like, oh, that was so cool. What was fun is like when we first moved into Los autos it was a pretty sleepy town and there wasn't much like there wasn't much going on at night there wasn't much um for the kids to do and you know i have to say it's like it's been such a pleasure because like you can buy buildings i bought buildings and um and then i could bring in you know really extraordinary owners who love what they do so like linden tree it's an amazing bookstore you know bookstores and this is where i was like i have a pleasure i can like help get a building i can renovate and make it nice and then you know create an environment and an economic environment where it can support a children's bookstore um we started state street market so that we could have the best thank you so much so my whole idea there was like i want to go somewhere where i can bring the whole family and everyone's happy and in the earliest days i remember i would go out, we had 17 people in the family.

37:45And like one, you call a restaurant, a restaurant, you're like, I need a reservation for 17. Everyone's like, no, and they hang up. So now like, it's easy to go. Everyone's happy. No one's fighting. And if like a child throws spaghetti, like it's not a big deal. And so I wanted something that was truly multi-generational. And I think it's also, I think society, it's important you have multi-generation. It's important that young people are exposed to older generations and that people in the midlife, you have support for your kids and, you know, that you can support your parents, that, you know, your kids are support.

38:24Like, I just think multi-generation is so, it's so valuable for how everyone grows. I think that's your Slavic genes playing out.

38:35Marina Mogilko:Because, you know, we were, I was raised by my My grandparents, everyone lived together and was like a small apartment. But my grandparents come over, we'll sleep on the floor. But they will help raise me. In the U.S., I don't see that. Parents are very lonely. They move to another town, sometimes another country. And so you're just raising a kid in a completely different environment. And the sense of community is getting lost, especially in big cities. Well, that's why I wanted, because I think so many people come, so many people are in Los Altos and they are immigrants. They don't have family around.

39:05And so my whole thought process was like, well, how can we use downtown Los Altos as a community? And it's also really fun to get kids excited about the different businesses. So I love, you know, like when we did the arcade, I would ask my kids, I was like, OK, make a business plan for each machine. Nice. Like, you know, tell like tell me what machine you want. My son the other day like wanted some machine was like two hundred thousand dollars. I was like, OK, well, like just do the math on that one. When do you get an ROI on that machine? Great task. But it's good. like I want more and more for kids also to be able to learn I think also learning about business and having lots of small business owners is great because you want I want kids to be able to like understand that they can create as well like you um you have an idea like my daughter wants you know a clothing store or something like or like I I always think about like should 23andMe create a retail store like a like be able to walk in experience yeah an experience I think it'll be So fun.

40:02So I'm always I'm always thinking about that. I'm always thinking about what else can I create?

40:07Marina Mogilko:Thank you so much for for downtown. Yeah. And all the things that you were doing. So 2024 was a brutal year for you with bankruptcy and having to buy out your company. Did you ever have thoughts of giving up like this is not something I want to do? I just want to live a happy life. I thought about it a lot. Like, do I because it became, you know, there's moments where I'm like, is this a sign from God that like I should give up? because like everything is pointing in the direction that things are not going well. You know, there's I called a friend who had also started a company and given it up and had walked away.

40:41And he he was like, look, I think about it every single day of my life. He's like, I just always regret it. Like, I just I wish I hadn't. And in some ways, it's I felt like I had a responsibility. Like one, I love 23andMe. So there was a selfish component of like, I just love it. The second thing is like I felt a real moral responsibility to my customers, all 14 million and my employees. And the responsibility that I felt was that I promised them that 23andMe was going to be a company, a mission driven company focused on helping people access, understand and benefit from the human genome. I really believe strongly that you want the company that owns that genetic information should be a neutral party, meaning that they should be supporting research all around the world, but it should not be owned by a single pharma company.

41:35It should not be owned by a single entity. And I thought about like my sister, like my deceased sister, her genetic information's in 23andMe. I don't want that owned by a single company. I want every single researcher in the world who's doing lung cancer work to have access to be able to make a difference. And like this is a community that came together to make a difference. I felt this huge moral responsibility that I should do whatever I could to make sure that we were true to that mission. And I feel really lucky. I feel really, really lucky that I got it. And I'm not a person that was like, oh, I really wanted to just like hang out and like sit at the pool all day.

42:16I would love slightly more work life balance. And I would like I am trying to take like have again now I have an amazing I have 175 people at the company have an amazing management team. So I have more of that time to do things like this and to, you know, volunteer at my kid's school and things like that. But, you know, it's kind of all the things that we talked about at the very beginning is that you want to do something in your life every single day that brings meaning. yeah and if i thought of again anything that i learned from susan was like contributing on a daily basis and feeling like you're having an impact on the world is the most important thing and it was a really really hard year and there's definitely things i would have changed um but

42:57Marina Mogilko:i love what i do what's your key learning from that year there's a dark side and then there's like the positive side i think the dark side was i was really surprised that um how many people backed away from helping me. I was really surprised in bankruptcy at, you know, the friends who showed up. And so I think it kind of came to me as a bit as like, you know, you do live, we're in Silicon Valley, it's a very competitive, aggressive environment. And I have always, like, I operate in a way where I feel like I try to always be honorable, and I try to be genuine and ethical. I think that was like one of the hardest things for me is like, wow, like I might be playing in the wrong community and in a community of people that are not necessarily there to support.

43:47I think on the positive side, the thing that impressed me the most was, you know, my customers and my employees who rose to the challenge. I couldn't do it without them. And they were there. They stuck with it. And they also like they embody the mission and they care and they feel this responsibility and that passion. And there's really good people in the world. You have to just make sure that you spend the time with them and align yourself. Like, I feel really, really good every single day that I feel like I'm doing things that make a difference. Like, I'm doing things that make a difference with 23andMe.

44:25I'm totally unfettered on making decisions that are really about best interest of humanity. I love what I do with Los Altos. I love what I do with Susan Wojcicki Foundation. And I work with extraordinary people. Having a community that supports you and supports the mission and you can trust them is a really special thing. So, you know, I think about like community is a theme that I have throughout my life. Like I have my family I'm really close to. I've tried really hard to build a community in Los Altos. I have a very strong 23andMe community and I try to have a really strong like 23andMe experience and ecosystem.

45:03Be a brand that fundamentally is always going to be trusted and have the back of customers.

45:09Marina Mogilko:I really like what you said about being true to yourself. It's tempting to be dishonest to chase success, especially in Silicon Valley when everyone's moving so fast and people are cheating. I love that. Whenever I think about projects, I think about how can I do them long term and be true to myself. My parents and my grandparents and everyone, I think also people, again, you're an immigrant. My parents, my dad escaped communism and his father was imprisoned by Stalin. And I just think about the really important decisions that people made that really impact society. And I want to be somebody who's always operating with that kind of ethical compass.

45:55Marina Mogilko:Yeah. Talk to me about your kids. Yeah. Yeah, you made they are and you made such an inspiring decision. Like I've never thought about that when I realized you had a baby at 40, 45, 45. So I told you I really want a third kid, but I don't feel like I'm ready. Like these two are a lot. Talk to me about that decision. Did you have any concerns about having a kid at that age? Being divorced was really, really hard for me. There was the aspects of like the loss of a family. but there was also the loss of like oh my god I like I want to have more kids I felt really determined that I was not going to let you know a marital status impact my decision to have kids and at the same time I think I always joked with people that the only thing worse than one custody agreement is two custody agreements and so I was I was very I was very gun shy I was like okay am I actually going to reproduce with like another consenting individual i ran into my my ob one day at pete's and i was like oh i want to have another child and she was like you do and she was and i was like oh shit you know you're right like i i should get on this and you know they kind of torture you going through a donor a sperm donor process where you have to like like do all these therapy meetings did you pick a scientist or something like someone with a PhD yeah no I wanted I wanted to find somebody who was gonna characteristics that would be that would match in well and um and I I listen I like it was it was one of those things like I was really um I went into it I would have we get you have to go through all this therapy and everyone told me you're never gonna get pregnant you're never gonna get pregnant you're never gonna get pregnant and so you had to do all these therapy sessions doing it I was like I get at you guys like I'm old and my numbers are bad um but I'm just gonna try it because if you don't try you never know you never know but I didn't even do a pregnancy test because I was like oh there's no reason like first attempt it worked no the first I actually got pregnant the first time and then I miscarried but I was like holy cow like the machine works um and and then a couple months later I got pregnant and I just every and I I was almost in denial like even at eight months I was still like riding my bike around and I was like, ah, like, I think I'm pregnant.

48:13So it was an easy pregnancy. Yeah, I'm so lucky. I mean, I'm so, so lucky. And I feel for all the people who've had like tough reproductive journeys and all this. And I do think on all these areas like stress, again, going back to stress and that impact, like the fact that I really went into it like, OK, like I don't think I'm going to get pregnant and I have to just be OK that like I have two really amazing children. Like I always tell people like walking, having a mentality where, you know, failure is the likely outcome. But but you're trying still. Yeah. And it helps. It helps put much stress on what you're doing.

48:51Again, it was a whole journey of like, OK, well, like I'm having I'm doing this on my own. And I had, you know, one of my best friends at the late my labor was a party because I had I was like I was like a communal. We're like all going to raise this baby. And and it was so fun. family is the best and um I spend a lot of time with family I um dedicate a huge amount of my energy to the family and you know part of it is like you have to invest like good relationships come with investment but I am really lucky to you know have three kids that are all you know

49:28Marina Mogilko:so far pretty nice to me how was raising her like the early days uh when you were 45 yeah all good is it easier than the first big kids help okay i'm a big believer like people having an age gap is really fun because you're just so much more relaxed and also you're more secure with your job you know what you're doing it's your third kid you're just secure with everything and the big kids come in to help they like you can go out to dinner and they watch them and you're just like you know that they're likely to survive like you're not you're not so incompetent that um that you'll do like you're just in you're comfortable with school and like clothes and i mean it's amazing like my daughter doesn't have to buy anything because like we just like we have you saved all of it okay good we saved like not only like some people come to the house and they're like wow your house like a playground i'm like i'm i'm like the accumulating it's like it's like a funnel like all the kids stuff like all 10 like it's all come down to us and so we have like tons and tons amazing of of items from the last 20 years do you have any hard rules when it comes to being a working mom.

50:33Marina Mogilko:Like I'm home by six. I don't work on weekends. There's no difference. Like before I had kids, I was like a machine. Like I was like always working. I remember I would sleep and like my Blackberry was like next to my head. Like it was, it was like my companion. I mean, now I'm very clear. Like I go to bed when the kids go to bed. I try to almost never do a dinner. And in those early days with the kids, like and early on, like my kids came on a lot of my trips. I try, I'm not good with boundaries. Like I remember my son at the European Society of Human Genetics. and i told him i was like take a notepad and go and interview how old was he he was like seven and i gave him a little notepad and he was walking around to all the booths and i was like just interview people and ask them questions and then come back in an hour that's great experience it was great but he came back and i remember he's like i've learned genetics is very important but i i i try to almost always do dinner um i think the other thing is don't like you have to show up like I have to like I try to volunteer pretty regularly with the kids the older kids are are cute they'll say like oh you don't have to drive me so and so and where but they actually really want you to and so showing up is meaningful and you have to then really prioritize what do you do at work and I think for me also as a leader I try to make sure that trickles down to everybody and be really respectful of people at dinnertime and at like seeing their children's performances or somebody's moving their child into college.

52:04Like having true work-life balance and respecting people is important. And I think as a leader of a company, if we want to change society, you have to honor and respect that people also have to support their families. Totally. And so like if the world is saying like, oh, there's, you know, fertility crisis, you have to have more children. okay have more children but then you have to be work friendly and so you can't have both you can't be like oh it's a 996 world six weeks off after having produced it's like it's not feasible and so i had um i mean that was the thing i had 23me does hire a lot of women and so like i regularly had like i would like be breastfeeding with my child and like in meetings and like doing different things like everyone it just became very normal my primary rule is again to be super friendly family friendly as a company to make sure that I sort of ruthlessly prioritize what's actually important and to be home at a reasonable time.

53:00Makes sense.

53:00Marina Mogilko:I wanted to ask you about being married to Sergey. I don't know if you want to answer it, but it's just I wonder if two very ambitious people who have their companies can coexist in a marriage with kids. What would be your learning? Well, our example said no. So I think it definitely can. What helps survive? help. You know, it's interesting. Like I remember talking to Jane, the CEO of Citibank, who, and I have to say, give kudos to Citigroup that she when her kids were little, she took off. I can't remember if she stopped working or if she went part time for a while. But like, she recognized at some point, like, I'm, I'm taking on more responsibility.

53:42Now I need more of that time. And then went back and obviously went on to be incredibly successful. I think in a relationship, it's always it's always a push and pull and in the early days my kids wanted me all the time and it was hard like my kids like really wanted me around all the time and they wanted to be at my house all the time they're older now and you know like frankly like my kids are like really clear they're like um you're not helping us with math homework that is and or like if they're 3d printing stuff they're like you know there's some things mom that you're good at and there's some things we go to him for you know i think it's you you kind of step in and out at different times so i think that's the beauty of a relationship that works well is that you can support like it's pistons it's piston engine and you're just you know responsive at different times but it is that recognition like it's hard like who's gonna cook who cleans i mean like the amount who gets to travel because there's only one person who can travel no at a time 100 i mean in the early days for me because my kids wanted to be with me all the time.

54:48They were like traveling with me. And I remember I have this like image of us like going at the train in DC and I'm like carrying car seats and like the kids. And I was like, and you have a meeting to prep. Oh, a hundred percent. And I remember the, I mean, the stuff that we did, it was like, it was so crazy. Even I remember after the FDA warning letter and, you know, being at the white house and I was like, can I bring my kids and how old were they like then small enough to spill m &ms all over the floor it was hard it's like definitely it's it's i read like respect like for all working parents recognizing it's hard and if you have two people who have like high pressure jobs um and that's the reality for a lot of people in silicon valley because you won't survive here otherwise i know you can't survive in one well i think this is where you need community comes back to yeah 100 i look at like there was one day where my youngest again I had meetings I had something to do and I was just like calling my neighbors I'm like so what's your daughter doing right now do you want my daughter too and they were so great they're like 100 bring her over like well you know and she had the time of her life she was so happy so leveraging the community is the only way you can survive you have to support each other and I think that's where like the pandemic did open the world of like okay we can have um you know people who are remote people like lots of people at 23 moved home you know moved away to be near family who could help with kids like completely understand like all of that is is key like it's hard like you

56:24Marina Mogilko:have to have support tough but somehow we're making it work uh yeah yeah with the dog on your lap yeah that's how right all right one last question can you finish this sentence for everyone who's watching the smartest thing you can do for your body in 2026 is one everyone should get genetic testing hands down like everyone should know what their genetic risk is second exercise every day just like right now every day 100 like but small things and i think people shouldn't get overwhelmed do 50 squats a day broken up into five segments like do 10 we're gonna do we're gonna do squats after this like because we've been sitting for an hour like just something small the way to build the habit is like you just do something small every day and then i'd say like cut out soda no even probiotic what do you have with you what kind of soda i think that was just sparkling water i have in general like i i was thinking about like understanding what your core risks are and then exercise makes a huge difference in your life yeah and so like the more you can just integrate it into your life like take the stairs instead of the elevator you know do some jumping jacks like if your kids are playing you play move around get a walking like a standing desk things like that like it makes a huge difference like walk the dog um but like all of that makes a big difference and then on food like my kids are really good we have a garden but i try to make them like have a salad have cucumbers like my kids are very good at eating cucumbers with salt but like just something like I avoid sugar like I and as soon as I cut it out it's like I never want it again so like I just never um have like soda like sugar sugar water is just like one of the worst yeah things for you I always have my vegetables love it thank you so much and it looks like what you are doing has come together in this day and age with AI yeah it looks like you've been preparing for this i mean i think that the i i mean going back to sort of where we started i i do feel like you know 23andme in many ways has just been very early we set out like i look at my deck my fundraising deck from 2013 it was like you know we're not a genetic testing company like we're not just you know an ancestry company like we're a big data company and that goal has always been like fundamentally if you can understand the human genome we can all benefit and so that's why that The mission has always been, you know, help people access, understand and benefit from it.

58:51We're set up like everything about how we set up our research infrastructure and how we consent people. And we give people choice and transparency. And we've created this community. It's like 14 million people, 90 percent have opted into research. We collect tons of information on. We ask our customers questions like, you know, do you have dogs or you do have allergies? And we can do extraordinary research. like people have no idea how many insights we have across everything from like fun phenotypes like you know handedness are you left-handed right-handed eye color medication response you know pet allergies cancer risk like all of it it's it's extraordinary and suddenly now with ai it needs data sets and you know the number one thing for us blocking you know 23andMe again we have the NeurIPS paper on doing risk prediction, like what we need next is just like we have capital, we're capital constrained, and I'm resource constrained.

59:47But those are all things that we'll fix in time. And so but the world is suddenly primed, like the technologies there, we have the data that's there. And I have customers who are hungry to say, like, let's go and we want to be healthier, we want to prevent disease. And like, the world is 100 % moved into

1:00:05Marina Mogilko:that that space now and that's amazing that you never gave up yeah we're stubborn yeah thank you so much thank you so much so inspiring thank you