In short
Skin Anarchy Podcast Episode Summary: Rewriting Allergy Care with Lorne Lucree of Wizard Wellness
Episode Overview In this episode of *Skin Anarchy*, hosted by Dr. Ekta Yadav, beauty industry veteran Lorne Lucree discusses his innovative approach to allergy care through his brand, Wizard Wellness. The episode details Lucree's transition from a successful career in major beauty brands to tackling the largely unchanged allergy care industry.
Key Themes and Concepts
Evolution of Allergy Care
- Static Nature of Allergy Treatments: Traditional allergy treatments focus on reactive symptom suppression rather than proactive biological support.
- Reframing the Nasal Cavity: Lucree suggests viewing the nasal cavity as a living barrier system with its own microbiome, similar to skin, which plays a crucial role in overall health.
Microbiome Science and Innovation
- Application of Microbiome Principles: Lucree emphasizes the need to support the nasal microbiome to enhance the body’s defense against allergens and pollutants.
- Preventative Model: The conversation advocates moving towards a model that restores equilibrium in the nasal environment, rather than merely suppressing symptoms.
Consumer Insights and Market Research
- Understanding Consumer Needs: A survey showed that only 7% of consumers were loyal to their current allergy solutions, indicating a significant opportunity for innovation.
- Focus on Performance and Experience: 84% of respondents expressed willingness to change for better performance, and 78% for a better experience.
Product Development Challenges
- Formulating for Mucosal Tissue: The episode discusses the complexities involved in creating effective and safe formulations for nasal applications.
- Balancing Efficacy with Enjoyment: Lucree shares anecdotes about product testing and the challenges of making allergy treatments appealing to consumers.
Key Takeaways
- Holistic Approach to Wellness: Modern wellness encompasses beauty and overall health, emphasizing that wellness should not be perceived as separate from beauty.
- Importance of Consumer Experience: Enhancing the consumer experience is crucial for adherence to allergy treatments; products must be enjoyable to use.
- Innovative Product Design: Successful products must balance efficacy with a fun and engaging user experience to foster consumer loyalty.
Lorne Lucree’s Background
- Career Path: Lorne has worked with major beauty brands including L’Oréal, Estée Lauder, and Unilever, focusing on product development and innovation.
- Transition to Allergy Care: After years in beauty, Lucree ventured into allergy care, aiming to reshape the category through scientific insights and consumer behavior.
The Future of Allergy Care
- Redefining the Category: Wizard Wellness aims to change consumer perceptions and experiences related to allergy care, introducing a brand that resonates with modern wellness trends.
- Next Steps for Wizard Wellness: The brand is set to launch in Walmart and other platforms, emphasizing the importance of accessibility in allergy care solutions.
Conclusion Lorne Lucree’s insights reflect a significant shift in how allergy care is approached, merging beauty, science, and consumer experience to create innovative solutions. His work with Wizard Wellness sets a new standard for what allergy treatments can achieve, aiming for improved health outcomes through a proactive and holistic lens.
For more information on Wizard Wellness, visit [wizardwellness.com](https://wizardwellness.com).
Written by AI. May contain mistakes. Listen to the episode to check what was said.
Chapters
Tap a time to open that second in VOLauren Lucree's Journey in Beauty
0:45 to 6:48
Lauren shares his extensive background in the beauty industry and his career evolution.
“Every time I talk to you, I just like I just so much happiness comes into my life because you're such a positive person.”
Exploring the Concept for Wizard Wellness
6:48 to 10:10
Discussion on the inspiration behind Wizard Wellness and the integration of wellness and beauty.
“in such a real way, because like, you know, and I want to dive into that.”
Challenges in Allergy Care
10:10 to 12:51
Lauren explains the current landscape of allergy care and consumer behavior.
“things where you're like, my God, like, what are they doing to you?”
The Importance of Product Experience
12:51 to 14:03
A conversation about the need for better consumer experiences in allergy products.
“appear right so like you know when you're like making them believe actually that's you can actually have your like sliding doors moment.”
Exploring Allergy Solutions
14:03 to 14:36
Discussion on the importance of options in allergy treatment and the launch of new products.
“But if you don't have the options available, there's no progress.”
Understanding the Nasal Barrier
14:37 to 15:28
Insights into the nasal barrier and its significance compared to skin, including microbiome dynamics.
“So I think when I was kind of initially had this aha, you know, the short story was I was traveling.”
The Nasal Microbiome Revealed
15:30 to 17:25
Exploration of the nasal microbiome, its impact on health, and emerging scientific literature.
“So like utilizing specific, you know, fibers or prebiotics or whatever it might be to, and probiotics or postbiotics to specifically modulate the microbiome to do things, right?”
Clinical Validation of Products
17:26 to 19:56
Details on the development and clinical validation of allergy-related products and their effects.
“So I then worked with a specific partner that only focuses on microbiome.”
Quality of Life Improvements
19:57 to 20:51
Discussion on how product effectiveness translates into quality of life improvements for users.
“We were like, I think one of the first to kind of validate that in the nasal areas that I've seen in terms of like from a nasal microbiome approach.”
Challenges in Allergy Product Development
20:52 to 23:52
Examination of challenges faced in developing allergy products and the importance of rigorous testing.
“And the best part is that that's translational.”
Show all 16 chapters
Balancing Efficacy and Safety
23:53 to 27:49
Discussion on the need for immediate relief in allergy products while ensuring safety and efficacy.
“the surface area, but the permeability is a huge thing, right?”
Flavor Innovations in Allergy Relief
27:50 to 28:00
Insights into flavor innovations in allergy products and their role in user satisfaction.
The Challenge of Flavor in Allergy Relief
28:00 to 30:07
Learn about the importance of immediate relief in allergy products and the challenges of flavoring nasal sprays.
“Some people were like, this is the best thing I've ever tasted.”
Advice for Disrupting the Allergy Market
30:07 to 32:08
Discover key insights for entrepreneurs looking to disrupt established markets and create meaningful products.
“But that, I think that was an example of trying to drive efficacy in a way that then I was like, okay, maybe this is, this is a lot.”
Building a Unique Brand in a Boring Aisle
32:08 to 34:19
Hear how to identify white spaces in the market and the importance of a creative vision.
“about what it takes to shift your perspective and also build meaningfully in a new space.”
Where to Find Wizard Wellness Products
34:21 to 35:21
Find out where to discover the new allergy relief products and the brand's online presence.
“And I think anyone, All of our listeners, you guys got to check out the brand.”
Transcript
Automatic transcript. May contain errors.0:00Dr. Ekta Yadav:Hey guys, welcome back to Skin Anarchy. This is a wonderful episode. I'm so thrilled about it. I've been waiting for a long time to record this episode because I have a very dear friend with me today and I am probably his forever fan. We had him on the podcast before and he shared so many insights with us because he is truly one of the leaders in the beauty industry. He has worked with, I mean, think of any major brand, he's worked with them. He's advised them. He's been behind the scenes. And so his perspective, when I look at his perspective, it's literally the full understanding of the beauty landscape.
0:29Dr. Ekta Yadav:And so to now speak to him about his own brand is incredibly full circle. So without further ado, I want to introduce you guys again to Lauren Lucree. Welcome, Lauren. I'm so honored to host you.
0:40Lorne Lucree:Oh, my God. I'm so happy to be here. And likewise, you're such a legend. So thank you so much for having me. Oh, my gosh.
0:46Dr. Ekta Yadav:No, it's such an honor. Every time I talk to you, I just like I just so much happiness comes into my life because you're such a positive person. And like even like when I look at your brand and the way you've created it and just like I don't want to spoil it for our listeners yet. because I want to dive in, but it's just so fun. It's like the energy and the vibes and I don't know. I just love it. So I want to dive in, but first I want to kind of reacquaint everybody with your background because you are a legend in the beauty industry. You literally have seen it all, done it all. You've worked with so many brands.
1:16Dr. Ekta Yadav:Tell us a little bit. Give us the elevator version of everything you've been involved with in the beauty space. Just kind of walk us down memory lane a little bit.
1:24Lorne Lucree:Oh, God. Are you calling me old, Ecta? Is that what you're at?
1:27Dr. Ekta Yadav:No, I'm telling you incredibly accomplished for being so young.
1:32Lorne Lucree:Thank God for all this prestige skincare. Glad to have had a career that's been a bit like a dynamic, but I'd call it like a portfolio approach to like, I think, say beauty. So not quite linear, but I'd say purposeful and will make sense as we talk about the brand. But started my career in beauty at L 'Oreal in global marketing, moved to Estee Lauder working at Clinique and kind of technical product development. then moved to a company called Luxury Brand Partners, which was one of the first kind of luxury brand incubators at the time, working on brand called Arnco Hair Care in product development and innovation, so encompassing kind of packaging and formulation, which then expanded to create a brand called IGK in partnership with Sephora at the time.
2:16Lorne Lucree:And then that expanded to create a color cosmetics line called Smith & Cults, a hair care brand called In Common with the 901 Girls, a V76 with Men's Line, and then One Size with Patrick Starr. And then continued my career curious about the operations and manufacturing side, so moved to Voyant Beauty as Chief Innovation Officer. Voyant Beauty is the largest beauty and personal care contract manufacturer in North America, so formulating and filling for a lot of the brands you see in Sephora and Ulta and on actually mass retail shelves. and Mastige retail shelves. So there for about four years and then spent a year and change at Unilever Prestige advising their portfolio brands on innovation strategy with a heavy hand on Tatcha skincare, revamping their NPD portfolio and creating some of the things you see today, like the Dewey Milk Moisturizer and our longevity portfolio.
3:12Dr. Ekta Yadav:That's amazing. Yeah, I feel like you've seen, that's what I mean, like you've like seen this entire landscape. Not only have you been involved, but like see it move, you know? And I think that's one of my biggest questions for you is like, you know, when you were sitting down with a concept, like trying to like map out your concept for your brand, what were some of the major things about the industry that you were like, these are things I want to maybe change or like, you know, just, I don't know, do differently. Like, did you have that conversation with yourself, like internally? Like, where would I, you know, change things or not?
3:43Dr. Ekta Yadav:I don't even want to use the word change, like more like modify or like expand on, you know?
3:48Lorne Lucree:Yeah, I think that. Yeah, well, first, I'm like, I purposely, I think, chose wellness. Well, I think overall, I think where I found success in my career and what actually makes me passionate is, and as a creative developer, is applying kind of cross-category insights to different categories. And I think, you know, before skinification of hair was a thing, you know, was thinking that way humbly, you know, because I think that's, you know, I always found that that's an easy way to get consumers to understand. And that's always the goal for us is to get consumers to buy into the product and get excited without having to educate a ton.
4:28Lorne Lucree:And so that's such so whether it was applying color, color theory and our IGK color, you know, toning drops, which was the first purple drops to tone that you could add in and mix in, which was inspired by cover effects that we brought into hair care. Right. Or or skincare ingredients into into hair care or or Patrick bringing aerosol hair care technology into the settings on tilt on setting spray, like things like that. So I love that because I think that's really fun. And when you look at Wizard, it's literally bringing everything I've loved about, I'd say, beauty, skincare, haircare, and wellness into allergy.
5:13Lorne Lucree:And it all applies, to be honest. It's credible, it's science-backed, etc. But it's all actually, I think, intriguing and provocative to the consumer to get them interested. So when you read a p-page about a nasal spray, it should read a face mist, which is the goal, to get you excited. And that was my goal of trying to kind of think differently about this. And I think that's a reflection of where the industry is moving, is that it's all becoming so gray. We talked about this. It's like everything is melding and like wellness is becoming, beauty is becoming, it's all, and you've seen this mishmash happening, which is awesome.
5:53Lorne Lucree:It's this holistic approach to Inside Out and people thinking holistically about their appearance and that's linked to their mood and how they feel about themselves and it's all, and their sleep and it's all related, you know?
6:06Dr. Ekta Yadav:Yeah, absolutely. I mean, I honestly, like the first word that comes to mind for me is longevity now, you know? And I think that is such a solid point you made because wellness was never supposed to be separate. I mean, when I think about it as a scientist, it should never be separate from beauty, right? Because wellness is beauty. Beauty is wellness. And I think we lost that. I remember there were a few years there where we were kind of like floundering. It felt like that, at least, like the beauty industry. And in the sense of like we were making products, products were coming out regularly.
6:40Dr. Ekta Yadav:but that wellness part was just like, where is that? You know, like the overall like play. And so I think it's really fascinating that you've brought wellness forward in such a fun way, in such a real way, because like, you know, and I want to dive into that. Obviously, like allergy, immunology, it's a huge field and it's an incredibly underdeveloped field on the consumer side, as I'm sure you know much more than me. I mean, I can only tell you as a consumer walking down the aisles, you know, when I see these nasal drops that are literally thinning the mucosa, you know, and then I think the damage that's done over time, it's an incredibly outdated area.
7:17Dr. Ekta Yadav:So, you know, let's talk about that a little bit. You know, what was that initial homework that was there for you when you were trying to go into this new category, you know, and trying to understand it?
7:28Lorne Lucree:Oh my God. Well, the hours I spent in CVS and in South Orange, New Jersey, my God, Christ, like i'm sure i'm sure i'm on a list somewhere like that they're like you're on their vip list i don't know maybe i mean hopefully get distribution maybe but i mean what you see is like that aisle is like it's so pharma dominated it's like i'd say a lot of fragmented natural and homeopathic solutions and that's kind of the dynamic happening in the aisle um and i think that's it's been that way for a very long time i think that that's been and the innovation in the aisle has been driven by uh the kind of the movement of these these apis moving from kind of uh prescription only to otc so that's you know the last one i think was in the late in 2016 or 2017 um and that's that kind of drives excitement and then these new new ones become available and that's but it's but it's big headline is it's pharma pharma innovation driven and so dominated.
8:30And that in combination with allergy is just not, it's not like Sephora,
8:36Lorne Lucree:where people are scrolling on their app looking for new, exciting things. People aren't that excited about the product. So they're not shopping proactively, they're shopping reactively. So it's, you know, you wake up, you have allergies, you're going to the store and you're just buying whatever is there. And so that's in combination, then it's just kind of like you, there's not a whole lot of incentive to put new innovation out because consumers aren't really, you know, looking for it on the other side because they're just going and buying whatever is there. And so I think that is, that is, that combination just hasn't really, like, I think, spurred a lot of innovation in the aisle, to be quite honest.
9:13Lorne Lucree:So that to me was an unlock. We did a lot of, we did a 600 person survey at the beginning of this journey to understand because I know why allergies suck for me, but I wanted to understand why they suck for everybody else. And yeah. We realized only 7 % of consumers said that they would be loyal or extremely loyal to their current solutions, which makes sense because I've never heard – I'll tell you, I've had a lot of conversations about allergies. Never once have I had one that was like, let me tell you about how much I love my current, you know, solution, my current, you know, nasal spray. Like, never.
9:46Lorne Lucree:Yeah, like just my current thing to watch it.
9:48Dr. Ekta Yadav:Yes, never.
9:49Lorne Lucree:So that's, you know, so very low loyalty. 84 % would change for a better performance. 78 % would change for better experience. So there's this like performance, but experience matters. And that was to me was the unlock of like, if it tastes better, if it looks better, if it doesn't, if it doesn't thin my mucosa, if it doesn't burn, if it like all these things where you're like, my God, like, what are they doing to you? Christ, like, oh my God, like, like, so like, if you can close that gap, then like, then that's like, that's like a holy grail. So that's what we had in mind of like, listen, like it's got to be efficacious, but actually if you can make it like taste all those things from all the things from beauty and wellness, like if you make it taste good, if you make it like feel the scent, the texture matters, the packaging matters, all those other things matter that we know from beauty.
10:39Lorne Lucree:That's the thing. So it's like, you know, anyway. Yeah.
10:42Dr. Ekta Yadav:No, I mean, that's brilliant. And I love your insights because it really makes you think because beauty, I think the thing that beauty has done right, I think for so long is that exactly what you were saying, that discoverability component where you can play, you can have fun with it, you can find something that vibes with you, you know. And I think that really is something like health, like more health heavy products, you know, like pharma based products. Like they just don't think about that. The consumer experience is everything. It dictates, you know, if you talk to any clinician, they'll tell you like, you know, getting people to stick to their medication regimen is a huge problem.
11:18Dr. Ekta Yadav:You know, patient compliance. Like and where does patient compliance come from? You got to want to use the thing, you know. And it's like if you don't have options and if you don't vibe with whatever you're using or if it's not accessible to you easily, you can't drop it in your bag, take it with you, you're not embarrassed to pull it out. Those kind of components, if that's not built in, patients are not going to use their products. And it's going to lead to worsening of symptoms and worsening of everything. So, yeah, that's huge what you mentioned. And I think that's why I'm so fascinated with how you have approached wizard wellness is this idea of like, no, let's keep it efficacious, but let's bring in the fun part, you know, and that's really cool.
11:58Lorne Lucree:Thank you. Yeah. And the compliance that like actually, if you talk to any allergist, nasal rinsing is like, do you neti pot, by the way? Have you ever neti potted?
12:07Dr. Ekta Yadav:I have before. I don't currently.
12:09Lorne Lucree:So it's like the number, it's the number one recommended way to prevent or alleviate allergy symptoms. So because it's just like cleansing your body, it makes sense logically, but people don't do it because it's a lot of friction, right? You know, like boil water, you know, the whole thing. I'm like, every time I move, I have like, you know, 600 salt packets in my house that I throw away because it's like I never inevitably like never, you know. uh and uh i think but the key actually the unlock with it is actually it's most efficacious when you do it preventatively when you when you start ahead of time but nobody you don't consumers aren't trained to think about it and that's actually when we talk about longevity i think that's the interesting thing of like uh convincing consumers to actually do things before the symptoms appear right so like you know when you're like making them believe actually that's you can actually have your like sliding doors moment.
13:01Lorne Lucree:You can actually, you can control your destiny. And actually, you know, if you start to incorporate this into a regimen or ritual ahead of time and start to like live a bit more of like a wellness or more holistic, you know, approach. And so that's like the long-term goal, I think at the end of the day about compliance, actually using it daily. That's when you have the real unlock for sure.
13:22Dr. Ekta Yadav:Absolutely. Yeah. And I like that you, you know, I like that we're tying in longevity here because for a long time, I think longevity is getting a bad rap, you know, and it makes me kind of sad to see that because it's like the, I don't know, the term is like the first term I've seen in a long time that like defines like truly taking care of yourself for a long time, you know, and it's like, I don't know, I just, I feel like these are the kind of products I think about. When I think about longevity, I'm thinking about what is my everyday care that I'm using for myself. And so I think these products play such a huge role because people now are more health conscious than ever before.
13:59Dr. Ekta Yadav:We're always thinking, how can I enhance my routine? How can I fix something? Whatever it might be. But if you don't have the options available, there's no progress. Whether that's medicine, whether that's consumer behavior, it doesn't matter. Across the board. And so that's where I find it to be amazing that you launched. Now, I want to dive in because I know you've definitely done your homework. The efficacy is there with the products. Let's talk about the nasal environment, the nasal barrier compared to something like the skin barrier. Educate us a little bit on the actual science of everything that you kind of had to do a deep dive yourself into before you were formulating and creating the products.
14:36Yes.
14:37Lorne Lucree:So I think when I was kind of initially had this aha, you know, the short story was I was traveling. I used actually nasal spray that was actually performed that was natural. And the IL was like a really beautiful IL, you know, as a product developer, we love these things, right? So I was like, oh my god, this reads like a pee page. I'm like, what? Or like a Sephora pee page. I'm like, why don't, I'm like, why does, it looks like a face mist. And so I started going into this rabbit hole of like, why don't more allergy products get me this excited? And so then it was like checking these boxes of like, is it regulatory?
15:15Lorne Lucree:Is it manufacturing? Is it science? Like, what is it that's like holding people back from entering this category and disrupting? Like there's no armor of allergy, right? or, you know, or grooms of allergy, right? So, so the science piece of it, that was actually inspired by a lot of the work we're seeing in skincare and gut actually around microbiome, you know, seeing upstream around like, more so moving from this idea of like, respecting the microbiome, microbiome friendly, which is great, actually formulations to actually more like, of precision microbiome approach. So like utilizing specific, you know, fibers or prebiotics or whatever it might be to, and probiotics or postbiotics to specifically modulate the microbiome to do things, right?
16:10Lorne Lucree:So to actually perform almost like an active ingredient to deliver benefits. And like, so we're seeing it in skincare, you're seeing brands that specifically like lower the levels of staph aureus on the skin to treat eczema, right? So, or like gut products as well that treat kind of leaky gut or things like that. And so that was like, okay, well, would the same theory apply to the nasal passages, right? Like, so this, then this started this whole like rabbit hole of like, okay, does the nasal passages have a microbiome? Like what, like what, like what? So it turns out, yes, they absolutely do.
16:46Lorne Lucree:And then the nasal passages, and so the cool thing is, which I talked about cross category before is like all the same rules apply is actually the literature, which is still, I have to say, I have to caveat this, which is the really cool thing is that like all this science is really still emerging because there hasn't been a ton dedicated to the nasal microbiome and the science that still is emerging within the allergy field, but it is actually credible and is coming validated by some of our sources that, you know, competitors, but essentially the literature shows that those with, most likely with chronic rhinitis, most often show a microbiome in dysbiosis, right?
17:24Lorne Lucree:So that they often show an overabundance of certain types of bacteria and fungi, that then, when that microbiome is dysbiosis, it then shows a relative weaker nasal barrier, epithelial barrier, which then allows, essentially the The same difference allows more of those allergens, exposomal pollutants, etc., to penetrate and kind of kick off that inflammatory response, which then you see results in that kind of cascading effect, which is then all of the allergic responses that you see. So I then worked with a specific partner that only focuses on microbiome. We come through all the literature, figured out this was not a week endeavor.
Read the full transcript
18:05Lorne Lucree:This was the month's endeavor. Figured out what was actually credible. and then figured out actually what were the materials used and then kind of pieced together what we felt like was our best chance at kind of doing what we wanted it to do to achieve what we wanted and then moved into testing. And so essentially did a kind of like a preclinical validation. Myself, I participated as well, which is cool to see. Essentially what we did was a 28-day test. we essentially using almost like COVID tests like so swabbing the nasal passages day zero day three day seven day 14 day 21 day 28 and then using our products the nasal spray the nasal rinse and the oral strips once once a day tracking symptoms and then actually tracking the composition of the nasal microbiome and kind of linking those causality of in terms of like symptom you know either hopefully reduction, but also like quality of life cues in terms of like sleep and mood and appearance, all those things as well over the 28 days, and then linking how the composition changed with those factors.
19:16Lorne Lucree:And what we found was that our, what we call our nasal biome technology, but our blend of prebiotics and probiotics and postbiotics reduced staph aureus, which is the bacteria responsible, but then as well as specific type of fungus linked to, in the literature, are linked to environmental allergens, environmental and household allergens, which amplifies the inflammatory response. So, and over the 28 days, lowered both of those, and then linked to that improved quality of life. I had an overabundance of staph aureus as well. So, no surprise there. And so, it was cool to see at least in the preclinicals, and then we validated those in our full-scale clinical, which was on our 41-person panel study that we ran.
20:01Lorne Lucree:So, it was cool to see. We were like, I think one of the first to kind of validate that in the nasal areas that I've seen in terms of like from a nasal microbiome approach. I know that, you know, others have talked about microbiome we validate with a clinical and still seeing some of this kind of precision microbiome emerge. So I think it's more work to do, but I think it's really, really cool to see. And then especially cool to see, again, the improvement in quality of life, because in the 41-person panel study, it wasn't only like symptom reduction. It was improvement on sleep, mood, energy, wanting to socialize, which was wild, irritability, and then dark circle reduction at three weeks, puffy face, and then the microbiome fully shifting by 28 days.
20:50Dr. Ekta Yadav:Wow. That's really, really impressive. And the best part is that that's translational. that's that's where i don't you know i got this like bone to pick i feel like with like everybody that does these like random studies especially when you get into the other fields of like science because we do so much but then it's like how does this translate to reality and that is translational and that's i mean that's where i think it's a really really important to understand because allergy and immunology like just from my understanding like it's an incredibly difficult field because there is like you were mentioning like that the fungal you know like fungal organisms, for example, that's a chronic inflammatory response that your body is constantly dealing with.
21:29Dr. Ekta Yadav:And so when you are able to understand something like that, and then also start creating solutions that are going to target all of the microorganisms that you're dealing with. You know, I mean, staph, I think, is a problem all over the body. But then that really sparked my interest when you mentioned the fungal part, because I mean, I think a lot of times, especially now, because everybody has dysbiosis going on, whether it's got dysbiosis, whether it's in the nasal passages, it doesn't matter. I mean, that kind of is where the gut starts too, right? That's an important thing. It's like nasal, then oral cavity.
21:59Dr. Ekta Yadav:And, you know, you don't really talk about that, is that it starts that early and then it sets the rest of the, you know, the rest of the string up. And so if this is not checked up or it's not in sync, the rest of your gut is not going to be either. And so there's a huge cascade that's occurring and fungi are incredibly important in that, you know, because as I mean, you know, this, but I'm just saying for our listeners, you know, it's incredibly important because they dysregulate everything and they're chronic. It's wild.
22:30Lorne Lucree:It's wild. I honestly, and it's like, once you dive in, it's like, it's so great. Cause it's like on two things. That's like one, those results didn't happen on every four, all 41 people because not all 41 people actually had a microbiome and dysbiosis, to be honest, which was like actually the cool thing. So the technology on the people that didn't, we just like supported their microbiome so it was actually truly personalized in a way that's like which is why how i always envision personalized skincare but because that to me it was like personalized skincare isn't like a drop of this and a drop of this and you know like i mean that was to me 1.0 like went back in the day like to me personalized skincare is actually like interacting with the body of like so and and and and to me this is like the definition of working
23:13Dr. Ekta Yadav:with the body, not against it, which is like the holy grail of, so it literally is like figuring
23:19Lorne Lucree:out and then working with it, which is like wild. And then yes, the ability to then specifically like solve for this, which is, and then we do, we do have a patent on this, our microbiomodulation of, of the nasal area utilized on the gut nasal delivery. So, which is kind of cool. So to be able to kind of like with that two prong approach, because there's only so much surface area in the nasal cavity. So we're using the gut too, to kind of, to power that as well, to your point of that gut nasal access, for sure. Yeah.
23:52Dr. Ekta Yadav:And then also like, just to your point, you know, not only the surface area, but the permeability is a huge thing, right? I mean, that's why I really want to kind of pick your brain a little bit there, because how was that formulation, you know, that journey for you in terms of like really kind of rethinking, because that's such a different environment you're dealing with. I mean, skin is great. Transdermal delivery is great. And that there's a lot of, you know, hurdles there. So we got to get more robust with things like encapsulation, but this is mucosa. So mucosa is like, let me, you know, let everything in, everything goes straight to the bloodstream.
24:26Dr. Ekta Yadav:So how is that? Yeah.
24:28Lorne Lucree:Oh my God. Can I tell you, like, I'm like, you want a shampoo? I can get you a shampoo tomorrow. Like, I'm like, oh, this was like, again, this is the most challenging thing I've ever done in my life, But that's the joy, right? So it was a multi-step process. And there was all these chicken egg moments because you couldn't pass go without doing a certain thing. So every ingredient's been screened for toxicity in the nasal mucosal area and for ingesting given certain levels or told no. So because we're bringing in new ingredients into this category, right? So we had done research to show that we believed efficacy and then validated with a toxicologist that we were able to use these ingredients because there's the FDA recipient list, which is validated.
25:16Lorne Lucree:And then we were bringing in additional ingredients to be able to utilize, validated with a toxicologist to be able to utilize as well, and then formulated with. So that's kind of how we, and then safety tested, of course, all the formulations to validate. And then the other big challenge was preservatives. I mean, that was like the big, you know, you're like building all this and then you like to tear it down with a preservative system that's going to like, you know, kill everything is like not the smartest idea. So we so define I mean, God, I went through like 600 iterations to find a preservative system that was like, you know, still robust enough, but not was not did not irritate.
25:56Lorne Lucree:And so we landed on actually on a really interesting preservative system that's that's not does not irritate. It's peptide based that doesn't irritate, but still is robust. And, you know, of course, passes PET, et cetera, and is ingestible, et cetera. So anyway, so it was a combination of all these things, but a lot of steps and a much more extended development timeline as well.
26:17Dr. Ekta Yadav:Yeah, I can imagine. I mean, that's truly a feat. And I mean, I really applaud you for that because I think when it comes to innovation, you can't skip steps. And I mean, you know this better than I think anybody in the industry where it's like innovation. When I look at it, especially in beauty, I feel like sometimes we just – sometimes you skip over things, you know, and you can't do that. And I think the human body has to be the human physiology and everything has to come forward. You know, it has to be the center focus. And so especially with a category like this, I mean, you're redefining an entire category.
26:52Dr. Ekta Yadav:So this is going to shift how everybody else in the allergy space thinks when they think about what product should we be creating. I mean, I remember back in the day when we were in – I was in medical school and they used to tell us horror stories of these like these drugs meant for like nasal sprays. And they were causing like nasal polyps. And like there was like a huge, like so many problems, right? And I'm sure, I mean, anybody out there, if you've dealt with allergies, you've heard about this stuff. And it's scary to think that people were so aggressive, you know, with the approach rather than thinking, what can the physiology actually handle?
27:27Dr. Ekta Yadav:And where is that breaking point? You know, where is that point of biology where it's like, don't push, you know, leave it alone. and and so I mean I guess like that is one of my questions also is like when you were doing your homework about like I want to maintain my efficacy I mean you just spoke about the preservative system which I think that's brilliant because yeah that's one of the biggest components but then when you were thinking about how far can we really push biology what were I mean were there some hurdles that you were like god I don't know I don't know what we're going to do here to really you know optimize efficacy without compromising anything I mean any war like war stories you can tell us
28:01Lorne Lucree:about there you know oh gosh well i think you know one is like you know with this category what what you know because we talked to a lot of like i talked to a lot of like outside like you know folks that are the kind of exposure to this category et cetera and the one thing that got like you know i was like punched in the face with was like you have to deliver immediate relief like that's how you if you can't you're never gonna win because that's the you know and that's how that's why natural brands fail right because they don't and that's you know that's why because everybody that's the key hurdle right and so a lot of that is often delivered by actually like flavor like someone like the like a eucalyptus or that vapo cool or things like that given immediate because some of that sensation of immediate clarity right and things like that and so um we oh my god we uh so for an instance because we have our flavors arctic vanilla and botanical breeze which are our nasal spray flavors inspired by lip care so to make them like you know fun and flavorful anyway but uh so we so originally in our in our sinus rinse i had actually a flavor i had the arctic vanilla in because it was a nice it added a nice like for me i'm like i'm like you know i've not now by now tested all the products multiple times i've put so much on my nose i'm
29:15Dr. Ekta Yadav:like who knows you know anyway so i'm like testing all this stuff anyway so i'm like i love it because
29:19Lorne Lucree:it's like gives me like breathing you know menthol i love it we did a 40 person like product validation study with the nasal rinse with arctic vanilla in it. I mean, it was so polarizing. Some people were like, this is the best thing I've ever tasted. This is amazing. Other people were like, my head is going to explode. I hate that. I'm sure they would punch me in the face if they saw me after testing that product.
29:47Dr. Ekta Yadav:I was like, so anyway.
29:50Lorne Lucree:So needless to say, that was a turning point where we, I was like, that was a bridge too far in innovation. I was like, sinus rinsing in general, I think is a lot. And then adding the flavor was, you know, so, so needless to say, we launched with a free and clear version. And so we will, we will phase into that. But that, I think that was an example of trying to drive efficacy in a way that then I was like, okay, maybe this is, this is a lot. And so we pulled the, we'll pull the flavor out. Cause I was like, I can't, you know, this is this one, maybe we'll have to take them along or we need to rework how we formulate it in in a much more gentle way, modify the fragrance oil, whatever it might be.
30:28Dr. Ekta Yadav:You're also dealing with that whole olfactory hypersensitivity, especially women. Oh, my God. You know, Lauren, I got to tell you, to this day, I can't eat anything that contains seafood because of that exact reason. I have the strongest, and I know people have said this to me before, like when your taste is so closely tied with your olfactory response that like anything you taste you smell and it's so strong so i hear you when you say that because i'm like yeah for all us super sensitive people i can see that you know coming at you like
31:01Lorne Lucree:like what are you doing to me what did you do yes but that's cool i'm glad you i'm glad you
31:07Dr. Ekta Yadav:pivoted though you know i think that would be really really interesting to see you come out with all the different flavors but give us like us super sensitive people give us the you know bland version i guess that's really neat i mean i think that it's just such a fun i think the brand is just so fun and i think that's what i think draws people into actually wanting to take care of themselves i said this before but you know my biggest my biggest questions i think for you is like if somebody is trying to disrupt a space which you clearly are this is going to absolutely be game-changing i mean i think everybody knows that at this point because the allergy aisles are just the most boring aisles, I think, in a pharmacy.
31:46Dr. Ekta Yadav:So, you know, I want to get your advice from a business perspective now for it, because we have a lot of people that tune in that are budding entrepreneurs or, you know, just they want to understand the business side, you know? And so in terms of disrupting a category, creating category, defining products, what are some, I think, take homes that you can give us, some words of wisdom you can give us about what it takes to shift your perspective and also build meaningfully in a new space.
32:14Lorne Lucree:Yeah, I mean, I think it is, I mean, one, the conviction of believing in the idea and seeing the vision, you know, because that's going to have to, you know, the other part you didn't see was like, is probably 700 investor meetings I've had along the way of creating this you know i'm so blessed to have an amazing and amazing investors behind this brand that believed in it but it took them seeing the vision and i think that so this conviction of like seeing seeing how this is going to come to life uh from start to finish i think that they they bought into that and saw it so i think that's that's the first piece of it i think really defining that white space of where you're going to sit and really having a really really clear understanding of your competitive set and and where you want to show up in retail um you know we when we were when i was developing this brand i knew i knew this wasn't going to sit in a in a sephora at the end of the day i knew this was going to sit in you know we're launching in walmart and in the dot com and martin next month and in the fall uh in brick and mortar yeah so i knew this was going to sit in a more mass environment because that's where allergies sell you know so it had a clear envision of where this was going to be so i think having that like that understanding your competitor set and that that that vision of where it's going to sit um and then uh and then i think the last is just like that um maintaining that like that creativity around like um what can be i think not uh not feeling like you have to to either knock off or benchmark or do whatever the other competitors.
33:59Lorne Lucree:I think that's where the ability to disrupt can be really magical at the end of the day to bring something new. So, you know, we didn't want to make another, you know, Beekeepers Naturals or another Clear or another, I don't know, Flonase. We wanted to make a wizard, right? And so that's what we did at the end of the day. And I think it's hopefully it shows, you know.
34:19Dr. Ekta Yadav:I love it. I love it so much. And I'm such a fan already. And I think anyone, All of our listeners, you guys got to check out the brand. But Lauren, honestly, I can't wait to watch this blow up because, I mean, honestly, it's a whole category redefined. That's I don't know what to say. That's huge. That's huge. Hats off to you. You know, that takes a lot of courage. It takes a lot of just hard work. And I can't think of a better person to do it. And, you know, I'm just so glad that you didn't create another beauty product that, you know, wasn't going to be meaningful at the end of the day. I swear I'm not throwing shade at anybody when I say this.
34:55Dr. Ekta Yadav:I'm just being honest. I swear if I see another redundant product, I'm going to lose my mind. So I'm just so happy.
35:03Lorne Lucree:Well, thank you. Oh, my gosh. Well, thank you. And I appreciate all the kind words. Thank you.
35:08Dr. Ekta Yadav:Of course. No, it's really well-deserved. And I can't wait for everybody, all of our listeners, to discover the brand. So you did mention Walmart. I'm so excited that you're launching in Walmart. Where can they discover the brand right now? Is it the website or what's the best way?
35:21Lorne Lucree:Yes. So we wizardwellness.com and then we're available on Amazon and TikTok shop.
35:27Dr. Ekta Yadav:Awesome. That's great. Well, thank you so much. This has been so lovely chatting with you again.
35:32Lorne Lucree:Thank you so much. I appreciate it.
35:33Dr. Ekta Yadav:Thank you.
From the publisher
In this episode of Skin Anarchy, Dr. Ekta Yadav sits down with beauty industry veteran and product innovator Lorne Lucree to explore an unexpected frontier: allergy care. After decades helping shape iconic brands across L’Oréal, Estée Lauder, and Unilever Prestige, Lucree turned his attention to a category that had remained largely unchanged. What he discovered was striking—while skincare had evolved into a science-driven, barrier-focused discipline, allergy care still relied on reactive treatments designed for symptom suppression rather than biological support.
The conversation reframes the nasal cavity not simply as an airway, but as a living barrier system—one with its own microbiome, immune signaling, and protective function, much like the skin. When that barrier becomes disrupted, allergens and pollutants penetrate more easily, triggering inflammation that extends far beyond congestion, affecting sleep, mood, and overall resilience. Instead of approaching allergies as isolated flare-ups, Lucree saw an opportunity to apply principles from microbiome skincare: support the environment itself so the body can defend more effectively.
Lucree shares how advances in microbiome science opened the door to a new preventative model—one that focuses on restoring equilibrium rather than sterilizing or suppressing. He also reveals the complexity of formulating for mucosal tissue, where safety, compatibility, and biological precision become paramount.
At its core, this episode explores how consumer health categories evolve when science, design, and behavioral insight converge. Listen to the full episode to hear Lorne Lucree explain how barrier biology and microbiome innovation may redefine allergy care—and why the future of wellness begins with protecting the body’s most overlooked interfaces.
Don’t forget to subscribe to Skin Anarchy on Apple Podcasts, Spotify, or your preferred platform.
Reach out to us through email with any questions.
Shop all our episodes and products mentioned through our ShopMy Shelf!




