What are Blue Zones?

28 Aug 2025 · 46 min

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In short

Podcast Summary: Stuff You Should Know - What are Blue Zones?

Episode Overview

  • Title: What are Blue Zones?
  • Hosts: Josh and Chuck
  • Description: The episode explores Blue Zones, areas with an unusually high number of centenarians (people aged 100 or more) and discusses the validity of the claims surrounding these zones.

Key Topics Discussed

Definition of Blue Zones

  • Origin: The term "Blue Zone" was first introduced in 2004 by a researcher who identified a concentration of centenarians in Sardinia, Italy.
  • Popularization: In 2005, Dan Buettner, a National Geographic reporter, expanded upon this concept through an article and later books, discussing additional Blue Zones like Okinawa, Japan, and Loma Linda, California.

Common Traits Found in Blue Zones

  • Dan Buettner outlined certain lifestyle habits contributing to longevity, known as the "Power Nine":
  • Move Naturally: Regular, low-intensity physical activity integrated into daily life.
  • Plant-Based Diet: Diets typically rich in vegetables, legumes, and whole grains, with minimal meat consumption.
  • Harahachibu: The Okinawan practice of eating until 80% full.
  • Sense of Purpose: Having meaningful activities and relationships that motivate individuals.
  • Stress Reduction: Engaging in activities to lower stress levels.
  • Good Sleep: Prioritizing adequate rest.
  • Family Relationships: Maintaining strong family ties and caring for elderly relatives.
  • Social Networks: Prioritizing social interactions and community ties.
  • Spirituality: Many centenarians belong to a religious or faith-based community.

Criticism and Controversy

  • Validity Issues: Critics, including researcher Saul Justin Newman, argue that the data supporting the existence of Blue Zones is often based on faulty records and may be exaggerated.
  • Historical Context: Concerns date back to earlier studies in the 1970s regarding questionable age reporting in remote villages.
  • Statistical Anomalies: Issues like clusters of birthdays on the first of the month and discrepancies in vital records raise questions about the accuracy of age claims.
  • Alternative Explanations: Newman's research suggests that socio-economic conditions in areas with high reported centenarian counts can skew the data and that many claimed centenarians might not be accurately represented.

Recent Developments

  • New Research: Ongoing studies continue to explore the lifestyles and health markers of Blue Zone inhabitants, with mixed results.
  • Broader Discussion: The episode presents not only the lifestyle elements linked to longevity but also the importance of scientific rigor in validating these claims.

Conclusion

  • The hosts emphasize the importance of maintaining a healthy lifestyle while acknowledging the complexity of age-related studies. The episode serves as a thought-provoking discussion on the intersection of popular health trends and scientific inquiry.

Key Takeaways

  • Blue Zones are areas with higher concentrations of centenarians, popularized by Dan Buettner.
  • Common traits among these populations include strong social connections, a plant-based diet, and active lifestyles.
  • Criticism centers on the reliability of the data and the potential for exaggeration in reporting centenarian statistics.
  • There is ongoing research into lifestyle factors linked to longevity, highlighting the need for careful scientific validation.

Final Thoughts The episode illustrates the allure of Blue Zones in popular culture while also encouraging listeners to critically evaluate the scientific basis behind claims of longevity and health. The conversations reflect a broader inquiry into what truly contributes to a long, healthy life.

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Transcript

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0:00This is an iHeart Podcast. Guaranteed Human.

0:31on the iHeartRadio app or wherever you get your podcasts. Welcome to Stuff You Should Know, a production of iHeartRadio.

0:45Hey, and welcome to the podcast. I'm Josh, and there's Chuck, and Jerry's here too, and this is Stuff You Should Know, our episode on blue zones, which is not, well, we'll explain it. It's not immediately apparent what we're talking about. You have to kind of know the ins and outs. And I think that's kind of what we're going to do here is explain the ins and outs of blue zones. I don't know why I said all that. Yeah. Well, I mean, I'll just go and tell people right off the bat that a blue zone is supposedly an area on planet Earth where people, they have an extraordinary amount or a higher than average amount, rather, of people that live to be 100 years old.

1:26Well, there you go. Now you know the ins and outs of blue zones, everybody. But the story behind Blue Zones is what's super interesting, I think. It started, well, we're going to jump back to the 70s at one point, but it started out basically in 2004 when there was a paper that came out that said, hey, there's a large number of centenarians, people that live to be 100 at least, in a small area in the mountains of Sardinia, Italy. And the author of the papers shaded it blue on a map, called it a Blue Zone. And then in 2005, it really picked up steam because there was a National Geographic reporter named Dan Butner who wrote an article called The Secrets of Long Life in which he talked about Sardinia and his own finding of Okinawa, Japan and Loma Linda, California as two more blue zones and was like, hey, what's going on here?

2:19We got to figure this out because people there are living longer. Yeah. And the whole premise was, hey, don't you want to live longer? Let's find out what these people's secrets are, because clearly if there's a bunch of them clustered together, that means they're all doing something similarly. So let's get to the bottom of this, everybody. And the way that he put it, what if I said you could add up to 10 years of your life? A long, healthy life is no accident. It begins with good genes, but it also depends on good habits. Yeah, I mean, I think everyone agrees with that generally. Sure. But one of the reasons why it does seem like there's a set of habits that you can engage in from the Mediterranean lifestyle or the Mediterranean diet to getting out there and walking every day.

3:07A large part of that is based on how popular the concept of Blue Zones became. And you can thank Dan Buettner. I believe his last name is Buettner. Like he just blew the whole thing up. And I don't want to say single-handedly because there are definitely people working behind the scenes. But he's the one who made it, who introduced it to popular culture. Yeah, for sure. And sort of off the jump here, I want to talk one second about a side article I read in New York Times recently. Because one of the things that you're going to hear him talk about or us talk about him talking about is one of the things you can do to live longer supposedly is tight social networks.

3:46I just read a New York Times article last week about super agers. And it's not necessarily people that live to be 100. That's what Blue Zones is talking about. But it's just people that live into their 80s and 90s without getting dementia. And it was a pretty robust study. They had a large cohort over like 25 years. And they said some of them drink booze every day. Some of them, they have been smokers. Some of them eat a lot of red meat. They said the one single thing that they found in common with all of them was social relationships, active social relationships with people outside of your house and going out and seeing people.

4:22They said they tend to be extroverts. So people that go out and socialize with other people was the one commonality between all of them. That sucks. Oh, no. I'm in big trouble, man. We got to get you out, buddy. I guess so. I'm going to have to update my wardrobe. You're like, I'm eating fish and olive oil and walking every day. Doing everything else. I just don't want to talk to anyone but Yumi and Momo. I put my hand up by my face when I walk past somebody when I'm out walking every day. I thought it was really interesting because, you know, most of us in our Gen X category are dealing with aging parents.

4:55And I feel like everyone I know is going through it in some capacity. So I'm just reading a lot about that stuff lately. Oh, that's nice of you. Prepping yourself? Prepping myself so I don't do this to Ruby. Nice. You know? Nice. So, yeah, tight social networks, that is a big one as far as the blue zones are concerned. And I guess that's the only one that really matters. But they have other stuff, too, like you need to have a sense of purpose. And anecdotally, I know that makes sense because a lot of people, I don't know if a lot's the right term, but there are definitely people who die very shortly after retiring.

5:34Yeah. And in the United States, your job in a lot of cases is your identity and your purpose in life. People are like, family, forget that. Accounting is my purpose in life. And then once they retire, they don't have any numbers to crunch and they keel over dead. So that, I mean, anecdotally, that definitely makes a lot of sense. Yeah, for sure. But this Nat Geo article that Buechner wrote went viral. um Buechner was basically like hey this is it for me he did a TED talk uh and and has developed quite a a robust uh cottage industry around Blue Zones uh he's written a lot of books he's written Blue Zone cookbooks uh there's been a Blue Zone uh Netflix series there are Blue Zone branded like he copyrighted the term Blue Zone right and or trademarked it rather and uh there are skin care products and iced teas and there's hot sauces and you can do a Blue Zone retreat or pay monthly for a Blue Zone app.

6:35There's a lot of stuff that he's selling. Yeah, for sure. He basically blew it up into a lifestyle brand. Yeah, which is one reason some people have come along and criticized it and said, wait a minute, is this like real science and real research or is this just creating a brand and making money? I mean, not with maybe nefarious intent or anything, But, like, let's look at the science. And a big person that you're going to hear come up a lot in this is a guy named Saul Justin Newman. And in 2019, he put out a statement, basically, that said, hey, I think this is all just bad data. Yeah, he wrote a paper on it, essentially.

7:20Yeah, like bad record keeping on ages. Yeah. And this is not new. The idea of super agers or centenarians, especially ones clustered together, has been long controversial. Anytime somebody's come along and been like, hey, we found a bunch of people are living to their hundreds. Let's look at what they're doing so the rest of us can do that, too. But back in 1973, there was a guy named Alexander Leaf. He was a physician and he got kind of caught up in this whole thing, just trying to figure it out. and he wrote an article for National Geographic, just like Dan Buettner did in 2004, but this is in 1973.

7:59And he went to different parts of the world where there were anecdotally, I guess, a bunch of centenarians living, and he investigated and he found, yes, there are some groups of people around the world who have some sort of secret to aging late in life because there's a bunch of 100-plus-year-olds who live in these usually isolated areas. Yeah, but he himself, and credit to Alexander Leaf, he was like, you know what, this is after the article was published. He didn't just sit back and collect his million-dollar check and say, oh, I guess that's that. He was like, wait a minute, some of this stuff is nagging at me and doesn't seem to make much sense.

8:43So he kind of went back on his own research even and started looking through these records, basically. And he, in one case, he saw a death certificate of a man who was allegedly 168 years old. And he was like, that's pushing it, I feel like. For sure. And in another area, he met a villager who claimed to be 122. He went back a year later and the guy said he was 134. So he was like, all right. Five years later, in 1978, he partnered with a couple of other scientists to sort of get down to the bottom of it all and dug through records in these places and found a lot of, like, discrepancies where people were off by decades on their actual age.

9:23And they reckon that, like, I think they're doing this because it brings them a lot of prestige. Instead of being, like, 80-something years old, they say they're 105, and all of a sudden they're, like, the village elder, you know? Right, exactly. But a fraudulent village elder. That's right. Essentially what happened was an outsider, a Westerner, got tripped up into what is probably a custom in the area. Like that people just kind of inflate their ages. And people like Alexander Leaf are obsessed with finding out exactly how that happens and not stopping to be like, I don't know if this is actually real.

10:02But yeah, hats off to Alexander Leaf for going back on his own findings and admitting like, no, this is probably not right. Because they concluded without a doubt that the Ecuadorians in this village of Vilcabamba were fraudulent. Yeah. And he's like, I'm sure that also applies to the other places too. So everybody just forget the article I wrote. Yeah. I mean, that's a, again, hats off, because to put your own name out there is like, hey, I got it wrong. Like, I don't know if I would have done it. You don't think so? We do that all the time. Oh, well, that's a good point. Yeah, we correct ourselves.

10:40So we're going to introduce you to a couple of more people that factor in pretty heavily here. In 1999, there was an Italian researcher named Giovanni Pes, P-E-S, never heard that last name. No. He presented a paper at a demography conference, and then there was a—why is that funny? Because a demography conference is like party central? Yeah, I can imagine somebody going, what segment of the population here is ready to party? Yeah, or I wonder if they just stand around at break and look out on the street, and they're like, how many people do you think are over there on that sidewalk? Is that right?

11:14I said 64. What percentage of those people are smoking Marlboro Lights? So in that audience, though, where Giovanni Pest was presenting a paper, there was a guy named another demographer, obviously, named Michael Poulin, a French guy. And he had recalled this fiasco in the early 70s. And he was like, wait a minute. He's talking about Sardinia, Italy, that, you know, originally the area where Buechner wrote the article. Turns out Buettner wrote the article about this research on Sardinia that Giovanni Pess had done. Yes. So it's very easy to just assume that Dan Buettner came along and either piggybacked on Pess and Poulain's research or kind of invited himself into their little party.

12:01He was actually already looking into this. Like, I think as far back as 99, he had set up a project to investigate how Okinawans, who are widely reputed for living into their hundreds, and we should say healthy, not like decrepit old balls of yarn. Like, these are healthy people who still move around and do stuff on a daily basis. Yeah. How they were doing that. So long before Pez and Poulin put their stuff together, or I guess about the same time, but independently, Buechner was doing his own thing, too. So he didn't just come along and steal their idea or their research. Yeah, for sure. And as you'll see, they worked together for quite a while after this, too.

12:46But so Poulin remembered the thing from the 70s and he was like, all right, I'm going to go to Sardinia myself and sort of dig into this. So he did that, started cross-checking birth records and marriage records and anything he could get from archives, you know, in the town or from the church or whatever. And they are the ones, they put X's, when they clustered, they shaded it blue. And they're the ones, Poulin and Pez in 2000, that coined the term blue zone. Even though, I guess, Buechner trademarked it. So, I don't know. I'm not sure what happened there. I couldn't find anything about Poulin or Pez's reaction to him trademarking that.

13:24I wonder if it was, he did what? So, yeah. It's like all the X's, whenever they confirmed somebody, they started to cluster so much that it just became a blue region. So now Dan Buettner had a name for this idea, this concept that he'd been working on for years. And he, yeah, he took it and ran with it and turned it into that lifestyle brand. Pez and Poulain essentially were like, OK, that's fine. We're going to stay academic here and try to keep studying this. And Buechner would kind of come in and out of their research over the next couple decades. Yeah. And the key thing, as far as the original three places in Buechner's article, like you mentioned, he had already studied Okinawa.

14:10He picked up on what Poulin and Pez were doing with Sardinia. But Loma Linda, California is in there. And everyone was like, what the heck does Loma Linda got going on? And just last year, Buechner told the New York Times that Loebelin was apparently included because the editor at Nat Geo said, we got to get an American Blue Zone in there. Yeah. Like this needs to be. I know it needs to be like applicable to our readers here. So a lot of critics, of course, are going to come out and say, like, that's that just kind of that's not science. No, you don't like editors don't dictate scientific methods or results.

14:46Right. So, yeah, that's a big criticism. but and I think also like I haven't seen anything that says Poulain or Pess are irritated by or just like Buechner or anything like that but just looking at the whole thing thing from the outside Buechner just keeps attracting just you know contradiction or naysayer after naysayer and Poulain and Pess are like dude we're doing like real science over here like, stop giving our work a bad name because you're out there selling Loma Linda because your editor told you to put it into the original article. Right. Or selling hot sauce. Yeah. Selling hot sauce. It's another great one.

15:29But so in, I guess, his defense, Buechner said, well, actually, Loma Linda, statistically speaking, people there tend to live anywhere between, I think, four to 10 years more than the average California resident. And there's actually a really good reason for that. There's a huge cluster of Seventh-day Adventists there. And you'll remember from our Kellogg live episode on the Kellogg brothers, the Seventh-day Adventists kind of inspired them in their health food movement. They don't tend to smoke or drink or eat meat. And so he was like, that's great. We're going to include them in there. So it's not like he just threw a dart like the Bay City Rollers and picked whatever city that it landed on.

16:16Like there was a reason why. And it turned out to be a pretty good business move because five years ago in 2020, Adventist Health, which is essentially the hospital arm of the Seventh-day Adventists, they bought. the Blue Zone trademarks and all of the brand. So they now own it, the Adventists do. Very interesting. All right, I'm going to ponder that. Let's take a break, and we'll come back and talk more about Blue Zones.

16:56Hi, Kyle. Could you draw up a quick document with the basic business plan? Just one page, as a Google Doc. And send me the link. Thanks. Hey, just finished drawing up that quick one-page business plan for you. Here's the link. But there was no link. There was no business plan. It's not his fault. I hadn't programmed Kyle to be able to do that yet. My name is Evan Ratliff. I decided to create Kyle, my AI co-founder, after hearing a lot of stuff like this from OpenAI CEO Sam Altman. There's this betting pool for the first year that there's a one-person billion-dollar company, which would have been unimaginable without AI, and now will happen.

17:30I got to thinking, could I be that one person? I'd made AI agents before for my award-winning podcast, Shell Game. This season on Shell Game, I'm trying to build a real company with a real product run by fake people. Oh, hey, Evan. Good to have you join us. I found some really interesting data on adoption rates for AI agents in small to medium businesses. Listen to Shell Game on the iHeartRadio app or wherever you get your podcasts.

18:10So, Chuck, like I said, Buechner and Pess and Poulin all started working together in the early 2000s. And Buechner was funded by National Geographic. He was a fellow for them, I think even before he wrote the article for National Geographic. But they started funding expeditions to look for more blue zones. And in the mid-2000s, 2000s, the aughts, I guess, they identified two more, one in Costa Rica on the Nicoya Peninsula, and another one in Ikaria, Greece, which is between Greece and Turkey. It's an island between Greece and Turkey. It looks absolutely amazingly beautiful. But they added them to there because they went and studied the centenarians and said, yep, this qualifies as a blue zone.

18:59I was just laughing because I was wondering if the Nat Geo editor was like, I kind of want to retire near Sedona. See if you can find me some olds there. That's right. I heard there's ley lines there. I'm trying to sell the wife. Right. More recently than that, they've added more Blue Zones besides the area of Costa Rica and Ikaria, Greece. Singapore was added in 2023. That's in the book Blue Zones, Secrets for Living Longer. Colon, nothing to add here. Martinique in 2023, that was added as well. But this was not Buettner. Apparently, Poulain is the one that put that Caribbean island, which is a department of France, He put that one on the list because there were twice as many centenarians per capita than mainland France.

19:50And so they're saying like they're basically finding these things that happen and saying like, hey, that's that's a blue zone. We're going to call it that because we made up that name. Yeah, but according to Poulin's very strict definition, there has to be a higher than normal or usual percentage of centenarians, people who are over age 100, and that they typically are healthy, active. They're still living life, right? That is the true definition of a blue zone. I get the impression Buechner, including with Loma Linda, got a little fast and loose with the definition and that that's probably a point of contention.

20:30Well, they came up with each of them independently came up of their own list basically of things to do to live longer. Buechner has his they're called the power nine, which is trademarked. and Poon Lan calls his the seven principles. I didn't see if that was trademarked. I don't think so. Yeah, I don't think so either. Here they are. One is move naturally, and that is basically like you're not going to the gym every day and quote-unquote working out. You're just moving through the world. You might be herding goats in this village every day or working in the garden all day long or just walking back and forth to the village to do your daily trading.

21:08They found that if you just move naturally through the world as you age instead of just sitting on the couch, then you're going to live longer. Yeah. If you have the same daily routine as Balki Bartakomus, you are probably going to live into your hundreds. Good one. Also, eating meat in very small proportions or not at all seems to be correlated with living a long life among blue zoners. Yeah. Usually, essentially plant-based diets, some fish depending on where you live. Yeah. And then Okinawans are very famous for something called harahachibu, which is the 80 % rule where you eat until you feel about 80 % full and then you stop, which is extremely clever because you get fuller and fuller after you start to feel full.

21:58So that rounds up to the full 100 % of fullness almost every time. Yumi taught me that. And it really works. It's also really difficult to stop eating when you're 80 % full when you're eating processed Western food. It's nearly impossible. But if you can pull it off, you're like, wow, this actually works. You should probably slow down, too. I bet that helps. That's what they say. Because all of a sudden, if you're like me, you're like, oh, God, I'm at 105%. Right. I was trying to stop. But also, if you slow down and really, like, you can sense the food that you're eating more, you can enjoy it more mindfully, too.

22:35So, I mean, yeah, for sure. Sense of purpose we talked about. It's called different things in different parts of the world. Costa Ricans call it Pura Vida. It's basically like, you know, do things that give you joy and like that you want to get out of bed and do. Like accounting. Right. Sure. If that's your thing. But yeah, I mean, it could be like a hobby. It can be anything. Like just having a reason that you're alive is that's your purpose. I think that's you got to have that, man. And I just hate to think that anybody doesn't feel like they have a purpose in life, especially like I get it.

23:11You go through like chunks of life, like say your early 20s where you're like, oh, my God, everybody else is more successful than me. And my life is off the rails already. And I'm only 20 years old. Everybody goes through that. So I can I can see like going through phases where you are lacking purpose or maybe direction is another way to put it. But like later in life to just feel like you've never had a purpose in life. I can't bear to think that that people feel like that, that anybody out there does. Yeah, for sure. Stress reduction is another. Reducing stress. I don't know why that's funny.

23:45But, you know, taking trips with your family, hanging out with your friends is kind of what I was talking about earlier with the social interaction. Right. And also get a lot of sleep. Yeah, that's very important, too. There's one that Buechner lists that Poulain doesn't. It's a religious faith. Apparently, they interviewed 263 centenarians together, and all except five of them belong to some sort of church or religion or a faith-based community. Surprisingly, most of them were Flying Spaghetti Monster followers. So you might want to look into that for longevity, too. Family first is another tenant.

24:29You know, live close to your family. Care for your old. Get together with your family. That's one. So, you know. We're both kind of screwed. Sure. What else? Strong social circles. That sort of ties into the other things we were talking about. But, yeah, you got to have those strong social ties. What about taking shots? Like taking a shot at your friend or taking a shot of whiskey? Taking a shot of booze, doing shots. Well, I mean, you know, they used to say that a couple of drinks a day, a couple of glasses of wine, like in Sardinia, Italy, is, you know, the kind of thing they do. They have wine with food, even during the daytime.

25:12They've now kind of gone back and say no amount of the World Health Organization, at least, saying no amount of alcohol is good for your health. So that was a disappointing finding. Yeah, that was another one that Poulain leaves off of his seven principles. He's French. Yeah, that's really saying something because they love the wine. I know. They like the wine. Yeah. So you mentioned Saul Justin Newman, who is the leading critic, I guess, of all of this. he says like yeah Buechner has turned this into a lifestyle brand and that smacks of all sorts of questionable stuff as far as science goes he goes even further than that he says the entire thing is based on a faulty premise in that there are no blue zones there are no clusters of centenarians who live in areas and live a longer life because of these lifestyle decisions and choices and things that they do, that just doesn't exist, that essentially the people who study this have been misled by their own data and that that's what is producing what seems like these blue zones.

26:25Yeah, and just in case you're wondering, he's a senior research fellow at the Center for Longitudinal Studies at the University of College of London. And he kind of starts out by saying like, hey, we noticed one thing. State issued birth certificates are really important. And 82 % of the super centenarians, and those are people over 100, were born before they started doing this widely, basically. So if we really had the real birth certificates of these people, that number of people living beyond 100 drops way, way down. Like essentially, everyone's lying about their age. Yeah, or mistaken about their age.

27:12But yeah, a lot of people apparently lie about their age. Also, Chuck, one of the other things that he pointed out is that if you study areas, especially in developed countries like Italy, England, and France, I think he specifically looked at, in areas with the biggest clusters of super centenarians, right? So I guess that's 101 on. Yeah. So those areas also tend to be more poverty stricken. The people have people living there make lower incomes. They have lower literacy rates, higher crime rates, very tellingly fewer 90 year olds, which is a big statistical anomaly because that suggests that people are just jumping into their hundreds.

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27:57Who wants to be like, I'm 92 when you could be like, I'm 102. Right. Yeah. And that they also have very paradoxically lower than average life expectancies. So if you put all that together, like you're like, how is anybody living into their hundreds in these areas, let alone whole clusters of people living into their hundreds? Don't make sense. I think Saul Newman's quote was feels hinky. Right. I think so. So what he concluded was that in these places that might have high poverty, you're more likely to find what's called pension fraud. So it's family members saying, no, you know, Grandpa Chuck is still alive in the back room.

28:40Keep those pension checks rolling in. And that's the thing. In 2010, there were more than 230 ,000 Japanese centenarians who were discovered to be either made up, dead or missing. Yeah, I think Greece also started investigating their centenarians and ended up finding 200 ,000 people who no longer were alive. So that's definitely part of it. Another statistical anomaly that he points out that is very suggestive of this whole thing being wrong is that if you look at the birthdays for super centenarians, their birthdays aren't statistically random. They seem to be clustered around the first of the month.

29:21there's a much higher, I think 150 % higher chance that a centenarian's birthday is on the first of the month than on the last of the month, which makes zero sense statistically speaking. It's like when I fill out any, like, tell us your age thing, I just go January 1st. Exactly. So do I. We have the same birthday, same fake birthday. That's right. Here's another one is that, and this is sort of part of the basis of his whole thing, is just that, like, these records are often wrong. They're very, very common. In the United States, and this was in 1960, 66 % of nonwhite females had multiple official ages in the year 1960, and their ages vary depending on what record you were looking at, whether it was like the DMV or a marriage certificate or birth certificate.

30:14And 30 % of these variations were off by more than a decade. Yeah. Yeah. And he also drilled down a little more and he said some of these lifestyle claims and diet claims, they're not supported by data. In fact, the Okinawan cohort, they were basically said to have this amazing diet where that's probably a big part of what was helping them live longer. He said, no, if you ask the government of Japan, people in Okinawa eat the least amount of vegetables of Japanese people as a whole, and they have the highest body mass index. So explain that, Poulain. All right. Maybe we should take our second break and see if Poulain responds to your call out.

30:59OK. Yeah. He might give us a ring. And we'll be back right after this to finish up on Blue Zones.

31:14We'll be right back.

31:39co-founder after hearing a lot of stuff like this from OpenAI CEO Sam Altman. There's this betting pool for the first year that there's a one-person billion-dollar company, which would have been like unimaginable without AI and now will happen. I got to thinking, could I be that one person? I'd made AI agents before for my award-winning podcast, Shell Game. This season on Shell Game, I'm trying to build a real company with a real product run by fake people. Oh, hey, Evan. Good to have you join us. I found some really interesting data on adoption rates for AI agents and small to medium businesses.

32:13Listen to Shell Game on the iHeartRadio app or wherever you get your podcasts.

32:30All right, so we're back. when we last left you, Newman had sort of launched a, I don't know about an attack, but put out a paper that countered a lot of these claims about Blue Zones being a thing. It's a big splash in the media. And so Blue Zoners got together and they said, all right, we're going to write a letter back to you defending our work. Like we will not, this will not stand. Yeah, and we should say Newman doesn't seem to think that Poulain is some hack or liar. Yeah, for sure. Poulain is a well-respected demographer. Instead, I think what Newman is saying is there are errors in the records that Poulain is using.

33:14Right. And once it's in there, when another record gets made from the original record, it just spreads like a virus, essentially. And so he's basically saying Poulain is using these faulty records without realizing it. And so an error introduced into your data would be totally undetectable in that sense. So he's not attacking Poolean specifically. He's saying like the data itself is wrong from the get-go. Yeah, which kind of even negates some of the rebuttal because some of the points of the rebuttal were like, hey, we know that there are errors and fraud, but we go through a pretty rigorous verification process and we think it's statistically sound.

33:59Like in Sardinia, you know, Italy, that was one of the first Blue Zones named. They said, you know, we have civil databases dating back to 1866. We have church archives. We've got these handwritten records. And we have done full genealogies of entire villages and cross-checked this stuff. So, again, you know, Poulain is trying to do the right thing. But Newman would probably go back and say, yeah, but those original records from 1866 weren't right. Yeah, but then Poulain would counter, yes, I'm not just using one record, I cross verify. So he interviews the centenarians first and their families, that's where he gets the original age.

34:38And then he goes back and tries to find any support that he can for that. And he actually came up with a rating system of how quality a verification is. I think there's a starring system. There's also like an A++++ or something system where like the highest quality verification is the centenarians saying their age. And you've got all these other documents that say the exact same thing and that they're, you know, a church record is not necessarily going to be based on, you know, a birth certificate or army registration or something like that. So that's pretty independent. And then he takes it even further and says you want to do the same thing for the family members, for their parents, for their siblings, and make sure that along the way somebody with a similar name didn't get mixed up and that that's how their age got older and older and older.

35:34He's doing like legit methodology. So it is kind of tough to just kind of dismiss that particular thing, the techniques he has for verifying ages. Yeah, for sure. Uh, another rebuttal was that, hey, Newman, um, a lot of the fraud and errors that you're citing weren't even in blue zones. You're just saying that that happened. Um, uh, you know, I mean, if it's happening elsewhere, it's probably happening in blue zones as well would be my counter to that. But, you know, that was what they came back with. Well, also in his paper, he does investigate actual blue zones like the Nicoya Peninsula in Costa Rica.

36:13Apparently, Costa Rica found out in 2008 that 42 percent of its population age 99 or older misstated their age in the 2000 census. And that when they went back and did the math to actually adjust it to reality, the blue zone in Nicoya shrunk by 90 percent. So he did demonstrate that, yes, some of these blue zones are just absolutely wrong. Yeah. It got a little personal, it feels like, at the end because they said, and also you're not a demographer. And your paper wasn't peer-reviewed or it wasn't published in a peer-reviewed journal, that is. And everyone says your breath stinks. Right. And you, sir, are a nitwit.

36:55Right. Although he was working at the Center for Longitudinal Studies. And by definition, he was a professional studier of studies and going back and recreating studies to find out how valid they were. So he might not have been a demographer, but he was definitely qualified to evaluate the quality of a study for sure. Yeah, absolutely. Dave helped us with this and he found a New York Times article from 2024. And this kind of, I think, for me, kind of makes a lot of sense. It was a quote from Dr. Nir Barzilai, I guess how you pronounce it. Sure. He's the director of the Institute for Aging Research at the Albert Einstein College of Medicine.

37:38And he was like, yeah, yeah, yeah. Eat all these good foods, stay physical, supportive friends and family. Like, I think we can all agree that you'll live longer. But his quote is, are the concepts of blue zones consistent with what we know about aging? Absolutely. But the blue zones themselves and the theories behind them have not necessarily been validated scientifically. It's not a study. It's an observation. It's an observation which is consistent with what we think we know about aging. And that's kind of where I landed was like, just say that. Say, hey, we've noticed this really interesting thing.

38:12And these are the commonalities for people that live longer in these areas rather than trying to say like, this is a blue zone and this is the data and the science behind it, you know? Yeah, there have been plenty of studies on blue zones and blue zone inhabitants. There's this kind of meta-analysis that was published in 2022, the American Journal of Lifestyle Medicine by Magdalene et al. I still don't know what et al means, but you know what it generally means by context, right? And others, I think? Sure. Yeah. Sure. But it examined essentially each of those lifestyle, you know, power nine or seven principles and the studies that support those.

38:55And there have been like really granular studies. They referenced some that studied elderly Ikarians. Remember Ikaria Greece is one of the blue zones? Studied their grip strength. Studied their flow-mediated dilation, which is a marker of the health of your endothelial cells, which make up the lining of your blood vessels. Like people have really studied this. And a lot of the studies have come back and been like, yes, these people have better than average grip strength. their flow mediated dilation is off the charts. You've never seen anything like it. Everybody says it's just amazing. So there has, there have been studies that support it.

39:36It's just like, I think people, people brush it off because it is very easy to brush off. I kind of landed where you did, where if you take it as a whole, it does seem to be great, you know, great indicators, There's great ideas of how to live. But the science is being conducted. It's just not there where somebody's like, yes, definitively, these are right. And these aren't right, too. Yeah, for sure. As far as Buechner and Poulin, they both agree that they think that blue zones are disappearing, like, quickly. And, like, there won't be any at a certain point, which is, I thought people were living longer.

40:15So I was kind of curious about that. But they're finding fewer centenarians in Okinawa and other places. And they say it's the widespread adoption of Western diet. Newman came back. I feel like every time they, like he's got a Google alert set for these guys. Newman came back and said, and I tend to agree with him here. He's like, that doesn't make any sense to me. He's like, are all these 80-year-olds suddenly giving up a lifetime of healthy eating habits and going to McDonald's? Right. Just doesn't make sense. so he goes back again to the record keeping and saying it was it was never that to begin with right he yeah it doesn't it just doesn't yeah it doesn't track so if they do exist though one thing that butner and poulain definitely agree on is and actually newman too is that they're they're not going to find anymore and the ones that do exist are going to shrink out to basically nothing.

41:11It's just different explanations of why that is. But you can kiss blue zones goodbye, basically. Yeah. Well, you found some interesting stuff on genetics, too, because that's kind of the one thing we haven't talked about is diet, exercise, being around your family and all that stuff is great. But genetics probably have to play a part, right? Well, yeah, they found you would think so for sure. And they have found some stuff that says, like, yes, these genes definitely do appear in certain populations more than others. Like the Sardinians have a gene that makes them bitter super tasters, I think, and it's related to lower fat intake, like you avoid fats.

41:52So that's something. I think it's associated with like living longer, that specific gene. Right. So that makes a lot of sense. Okay, that would definitely help you live longer. But then there's other contradictory evidence that is kind of confounding. Yeah, I think people 110 years or older, wow, in Okinawa, they had a slightly increased likelihood of possessing a gene variant that makes them more likely to develop Alzheimer's compared to, I think it was in Greece, that part of Greece that had the gene that supposedly protected against Alzheimer's. And they found the opposite to be true in Okinawa.

42:31Right. And yet they're both blue zone, super centenarian areas. Yeah. So, yeah. But surely it does have to play some sort of role. And I think in that original paper, Paz and Poulin speculated that inbreeding in that area of Sardinia was responsible for creating these essentially protective traits. Hmm. There you have it. Either way, the Sardinians were like, please, what are you doing? Yeah, stay out of our business. let me drink my lunch wine in peace. Well, supposedly there are plenty of areas in the world who contact Buettner and Poulan and are like, hey, make sure you put us down as a blue zone because it attracts a lot of healthy lifestyle tourists.

43:18Yeah, for sure. And again, I mean, I don't know why this bugs me a little bit more than usual. I think it's great that they put out tips for living longer, but there's something about like when it's marketed and branded that kind of, I don't know. I get you for sure. You know what I mean? Yeah. I'm with you, man. Although if you live the blue zone lifestyle and you're loving life, hats off to you. Yeah. Trademark Adventist health. Since Shuck laughed a second ago, that's a traditional trigger for listener mail. That's right. This is about circular economy and us complaining about appliances not lasting long.

44:04Hey, guys, I have something to say about this. One thing that people should do is maintenance on the products that they buy. Yeah, it's true. The fact that Chuck hates washers and dryers is because a lot of times products break down due to a lack of maintaining and caring for these products. I'm a home improvement contractor, and I can't tell you how many times I've moved appliances to see the total lack of care that these products go through. It's not just washers and dryers, but most things in your home that you buy, people fail to, one, read the instructions, and two, read how to cure for the products.

44:33Yeah, I just thought that stuff away. That's a good point, though. A lot of things these days require you to clean, maintain them so they do last longer. Take, for example, the clothes washer. Our clothes washer has three different small filters that need to be cleaned out once a month. What? Jeez. And if you don't, eventually it'll break down the washer. My point being, if you take just a little time and save and read those manuals, you'll help them last longer and you won't have to throw away stuff that breaks and wears down. I love the episode and I do 100 % agree that products are made to be thrown out and replaced.

45:03I just wanted to add that it's up to us as consumers to do our best to keep the products that we buy running the best that we can. That's my two bits. That is from Justin. And Justin, you are so right. And I, shamefully, never, ever maintain much of anything like that. That's funny that Justin wrote that in because just yesterday I was cleaning the evaporator condenser coils. I can't remember. Some coils in my fridge. Okay. Wow, look at you. Well, my fridge is not working very well, so I was really hoping that this was the problem. Bob Vila said it was probably going to be the problem. Oh, Bob.

45:41But in that same article on Bob Vila's website, he says that you should do that. You should clean and dust your refrigerator's coils every three months. Those are on the back of the fridge, right? Yeah. Or they're in the front bottom. But they make brushes. I got brushes for it and everything that make the whole thing easy. But I'm like, I have, this is the first time I've ever done anything like this. And I've had plenty of fridges. So it makes me wonder how much longer other fridges could have lasted. I'm sure that's true. But, oh, boy, I don't want to see what's under and behind my fridge at this point.

46:18It's scary. Well, I'm going to go look for the filters in my washing machine that I never knew existed. Because I get jazzed by that kind of thing. But at the same time, I'm like— I know. Me too. After a while, you're like, I'm tired of doing this. I changed my air filters and things in my HVAC. You mean I looked at a house once, and these two dudes owned it. and I was like asking where the air handler was and the guy didn't know. And I was like, you know, where you put the air filter. He's like, I don't think our system uses air filters. And I was like, dude. And we drove past the house the next day and there was an HVAC truck in the driveway.

46:57So I guess I turned them on to the existence of their air filters. That's great. Yeah, I actually do mine myself because it's not too hard. But yeah, that's as far as I go. and I should go further for sure. Are you cleaning out your drain lines? That's another big one. A drain line for what? For your HVAC. The little white PVC line that's like running from your air handler where you put the air filter. Huh? So this drains the condensation from your air handler and you should use about an eighth of a cup of just regular simple green. Mix it with a gallon of water. Get yourself a funnel. pour it in there, let it come out the bottom.

47:40You do that once a month during the hot months, and it will keep your drain line from getting clogged up with gunk. Yeah, I'm shamefully lazy about anything like that. I'm so bad at maintenance. I'll come over and show you. It'll be fun. We'll make an afternoon of maintaining stuff around your house. You buy the subs, though. Yeah, I was about to say, I'll bring the subs, you bring the simple green, and we'll party. All right, man, that sounds like a great idea. Well, thanks for this, Justin. and you really just kicked off a new tradition for me and Chuck. Monthly, I would say. And if you want to be like Justin and kick off a new monthly tradition for me and Chuck, you can send us an email too.

48:18Send it off to stuffpodcasts at iheartradio.com.

48:24Stuff You Should Know is a production of iHeart Radio. For more podcasts from iHeart Radio, visit the iHeart Radio app, Apple Podcasts, or wherever you listen to your favorite shows.

48:40Hi, Kyle. Could you draw up a quick document with the basic business plan? Just one page as a Google Doc and send me the link. Thanks. Hey, just finished drawing up that quick one page business plan for you. Here's the link. But there was no link. There was no business plan. I hadn't programmed Kyle to be able to do that yet. I'm Evan Ratliff here with a story of entrepreneurship in the AI age. Listen as I attempt to build a real startup run by fake people. Check out the second season of my podcast, Shell Game, on the iHeartRadio app or wherever you get your podcasts. This is an iHeart Podcast.

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From the publisher

Blue zones are areas where people supposedly have more 100+ year-olds than average. But is it all based on faulty records?

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