Most Replayed Moment: Are You Really Gluten Intolerant? It Could Be This Instead!

10 Jul 2026 · 20 min · 4 chapters

Ask about this episode

Ask anything about it. ChatGPT or Claude reads this page and answers with the times it was said.

Connect VO and ask about every podcast you hear, including the moments you saved. Add to ChatGPT · Add to Claude

In short

Sleep optimization is framed as key to recovery and decision-making, then the episode pivots to chronic bloating/gas and “gluten intolerance,” arguing many cases are actually constipation and fructan intolerance rather than gluten or celiac.

Guest backgrounds

Not named in transcript; the host references “leading experts” and discusses studies and clinical concepts (motility, microbiome, dysbiosis, IBD). No specific guest credentials are provided in the text.

Key claims

Prolonged morning symptoms suggest a real gut problem. Constipation can be “partial emptying,” not just infrequent poops; gas travels with stool and microbes ferment when stool is stuck. Gas/bloating has multiple causes: motility issues, damaged microbiome, and diet. Many people misattribute symptoms to gluten; wheat’s fructans (not gluten) trigger symptoms, and fermented sourdough can reduce fructans. Glyphosate exposure (via non-organic wheat drying) may disrupt the microbiome.

Notable examples

People farting until a morning bowel movement; “breakfast bar” study where fructans triggered symptoms but gluten did not; sourdough tolerated better than regular bread/pasta; antibiotics doubling IBD risk within a year.

Written by AI. May contain mistakes. Listen to the episode to check what was said.

Chapters

Tap a time to open that second in VO

Understanding Digestive Issues

0:27 to 4:30

Explore common digestive issues like bloating, gas, and constipation.

“And I asked them recently to send one to a member of my team.”

The Role of Diet and Microbiome

4:30 to 9:36

Learn how diet affects digestion and the significance of the microbiome.

“So, and the reason why this happens is because first of all, your poop is not just the leftover remains of your food.”

Clarifying Gluten Intolerance

9:36 to 14:03

Understand the difference between gluten intolerance and fructan sensitivity.

“is actually gluten intolerant but we all kind of think we are to some degree I think it's what's the numbers is it like 20 % of people think they are or something?”

Understanding Gluten and Fructan Intolerance

14:03 to 20:42

Explore the differences between gluten and fructan intolerance and their effects on gut health.

“One of them contained a very large concentration of gluten.”
Hear the part that matters, and keep it.Open this episode in VO. Double tap your headphones to save a moment as you listen.
Get VO free

Transcript

Automatic transcript. May contain errors.

0:00I've had many leading experts on this show, including Matthew Walker, and they've all said the same thing about sleep. They've said it's the biggest positive investment you can make in your own performance. You can have the best strategy in the world, but if you're consistently tired, poor decision-making will follow and eventually cause other things to fail in your life. So if you're looking to optimize your recovery, you should start looking at what you're sleeping on. Our sponsor, Helix, makes high-quality mattresses tailored to your body. It doesn't matter if you run hot, sleep on your side, or need something firm.

0:30Helix has a mattress for you. And I asked them recently to send one to a member of my team. And Juan received it. And we travel a lot. So when he's home, quality sleep really matters. And he told me he's getting the best sleep of his life. And the data backs it up with 82 % of people in a Helix study saying they saw an increase in their deep sleep. And with a 120-night trial, you've got four months to prove it to yourself. You can get 27 % off at helixsleep.com slash diary. That's helixsleep.com slash diary.

1:03on this point about bloating discomfort regular digestion if i have one of those things does that theoretically mean that something is not right everyone gets bloated once in a while so i think

1:15Dr. Will Bulsiewicz:i think it would be unfair to make it sound like you should never have any adverse symptoms at all but if it's prolonged but if it's prolonged if it's a chronic health issue if you're the type of person who you wake up in the morning and you say i hope today's going to be a good day I hope I don't have to deal with that specific issue. You have a problem. Like we already know. And then we have to work on that to address that issue. And how we go about that, I think, needs to be on some level personalized. But the tools that are at our disposal remain the same. So it's just a matter of like, let's put it on the table.

1:49Dr. Will Bulsiewicz:Here are your choices. You pick which ones are most applicable to you. Where are the opportunities for you? And I can't tell you that without knowing more about you. What about this issue of people getting gassy, like farting a lot? Yeah. Is that typically associated with one particular gut issue? Or is that, again, could that be a plethora of issues? So it could be a plethora of issues. This is a common problem. If I have to start with what is my number one thing, it's constipation. For sure. 100%. There are so many people who are listening right now that are constipated and they don't even know it.

2:23Dr. Will Bulsiewicz:because they poop every day and they think that how often they poop is the definition. And that's not true. So constipation is what happens when you're not adequately emptying your bowels. And that could be a frequency problem, but it could also be that it's a partial poop. Oh, okay. Cause I thought constipation was, if you just haven't been, you can't go, you go to the toilet and nothing comes out. Look, don't get me wrong. If you, if you don't poop for a week, I know you're constipated. I don't need to ask any more questions. If you go a week, but if it's, there are people who they poop every other day, that's their normal.

2:59Dr. Will Bulsiewicz:They feel fine. They don't have any gut symptoms. They don't have a constipation problem. We're okay. Right? So frequency is not the be all and end all. It's part of the, it's part of the equation, right? But there's also people who they poop and I want to sort of paint the picture and forgive me. I feel very comfortable talking about poop. This is what I've done for a living. But they go to the bathroom in the morning. They struggle. It's not satisfying. They had to work really hard to get a little nugget to come out. And then they feel like they still have to go. And maybe 45 minutes later, they poop again.

3:38Dr. Will Bulsiewicz:Okay, that's not a new poop. You're doing partial poops. You're probably doing a 20 or 25 % poop. So you could poop three, four times during the day. You might not still be fully emptying your bowels, right? And so that's an example of a person who can actually be struggling with bloating and constipation and not think because they're like, Doc, I'm pooping three times a day. Where is the gas coming from? Why do people, you eat something and then you fart a lot. What's going on? So gas travels with poop. You may, I don't mean you specifically, Steve, people listening. may notice this, that you wake up in the morning and you're farting like crazy.

4:20Dr. Will Bulsiewicz:And that farting continues until you actually have your morning bowel movement. And then once you have your good, healthy morning bowel movement, you feel solid and you're not farting anymore, right? The gas travels with the poop. So, and the reason why this happens is because first of all, your poop is not just the leftover remains of your food. Actually, your poop is predominantly your microbiome. 60 % of the weight of your stool is microbial. Really? Yes. When you say microbial, you mean like the bacteria? The bacteria. 60 % of it is the bacteria. Let me give you an example. If I took your drink and I added some soluble fiber, which is prebiotic, into your drink, there's no grit, there's no roughage, you don't even know it's there, and you're going to have a bigger, healthier bowel movement tomorrow as a result of what I just did.

5:13Dr. Will Bulsiewicz:Why? because I fed your microbes and they grow stronger and then they multiply. And because they multiplied, you have a bigger bowel movement, right? That's the way that that works. Now, don't get me wrong. You eat, you know, a salad, you're going to end up with a bigger bowel movement as well. But a big part of that is the fiber within that salad that's feeding these microbes. They multiply, they grow and you have a big bowel movement. So if that was my, if that percent of that would be the microbes? Sixty percent of that would be the microbes. Yes. So for that person, when the poop is in gridlock and it's not moving through, then those microbes are basically sitting there with unlimited time to ferment and produce gas.

6:02Okay.

6:03Dr. Will Bulsiewicz:So anything they come into contact with, they're just going to start working on it. So and it's not just like a fiber thing. Anything they come into contact with, it could be protein, They will ferment it. They will produce gas. So this is a big part of the reason why constipation is so strongly associated with gas and bloating. When people eat dairy and things like that, I think some people that have gluten, they often tend to get a little bit gassy. Yeah. Is that constipation? Gas and bloating is not just a constipation issue. I would argue that constipation is the number one cause of that particular issue.

6:34Dr. Will Bulsiewicz:But there's many potential causes. Number one could be motility. That's constipation. What's motility? Motility is the way in which your intestines move. So if the intestines move too fast and out of rhythm, you get diarrhea. If the intestines slow down too much, sluggish, you get constipation. We want the intestines in a rhythm because when they're in a rhythm, just like your heart, that's when they perform their best. So in a rhythm basically means predictable, consistent daily bowel movements. That's ultimately where we would love to be, right? And that, in a way, taps into like an entire circadian conversation that we can have later.

7:12Dr. Will Bulsiewicz:This is a part of your circadian rhythm is a fantastic morning bowel movement. Motility is just one of the causes of gas and bloating. The second is the microbiome. If you have a microbiome that's damaged and struggling, it's not going to be able to do its job the way it's supposed to. And part of its job is processing and breaking down fiber. because the fiber in our diet, we don't have the enzymes to digest it. So it works its way through the intestines, comes into contact with the microbes. And the microbes, they have literally 60 ,000 enzymes that we don't have as humans. They go to work as teams.

7:52Fiber stops being fiber, produces short-chain fatty acids.

7:56Dr. Will Bulsiewicz:This is the way that it's supposed to work. When your gut is not happy, they're weak, the microbes are weak. and you're asking them to do work and they can't handle that. And you end up with sloppy digestion and that's gas and bloating. The third thing can be your diet. So you just mentioned dairy, which contains lactose. Lactose can be easily fermented to produce gas. You mentioned gluten. Gluten itself is a protein. So can gluten technically be fermented? Yes, It could be technically fermented, but that's not really what's going on. What's happening is that gluten-containing foods, which are wheat, barley, and rye, also contain these carbohydrates called fructans.

8:46Dr. Will Bulsiewicz:And fructans are actually really good for our microbes. They're prebiotic. But if you consume a very large amount of them and you're not used to eating these foods, it can cause gas and bloating. These days, when I was younger, if I had pasta, I was fine. If I have pasta these days, I'm going to feel it for the next two days. Really? Yeah, I don't know. I don't even know what's going on. But then other people can eat pasta as much as they want, it seems. Out of curiosity, can you go to Italy and eat pasta and be okay or no? Same thing. I have not really tried. Okay. Anecdotally, I think when I remove, when I have like non-gluten bread or non-gluten pasta, I think I feel much better but I'm well aware from speaking to people like yourself that such a small percentage of the population is actually gluten intolerant but we all kind of think we are to some degree I think it's what's the numbers is it like 20 % of people think they are or something?

9:44Dr. Will Bulsiewicz:So like here in Los Angeles it's like probably 80 % of people think they're well like almost everyone's gluten free yeah right which they don't need to be and actually it can cause problems it can cause problems to be gluten-free unless you know what adaptations to make. So when you ask that question about Italy, what are you getting at? There's a processing issue in the United States involving wheat, which is that they allow the wheat to be sprayed with glyphosate, which is Roundup. It's a weed killer. And they do that to basically dry it out as quickly as possible. So imagine for a moment that you're a farmer and you have this field of wheat, you harvest it.

10:28Dr. Will Bulsiewicz:Okay. Here are your choices, Steve. You can wait a couple of weeks and let it dry out naturally in the air and store it somewhere. Or you can spray it with this chemical and it will be dried by tomorrow and then you can ship it up. Yeah. Right. And the problem is that glyphosate is not on the label. You would never know whether it's sprayed or not sprayed unless you're buying organic. If you buy organic, then by definition, they're not allowed to spray it. You would never know if it's there. The thing about glyphosate is that it's been approved to exist in our food system under the assumption of safety.

11:07Dr. Will Bulsiewicz:Because what it does is it shuts down this thing called the shikamot pathway. And that kills weeds or it kills plants. And we have a workaround. And it has to do with basically amino acids. We have a workaround where we can basically create those amino acids as humans, but the plants can't. So the plants die, we live. But there's a problem, which is that the microbes that live inside of our large intestine, they don't have the workaround. So that microscopic amount of glyphosate, you would say, well, us big humans, that's so small. Yeah, well, what do you think happens when it comes into contact with them?

11:53Dr. Will Bulsiewicz:we know that glyphosate disrupts the microbiome, that it depletes the beneficial bacteria, and the ones that tolerate it the best are the inflammatory ones. The bad bacteria. The bad bacteria. So you're shifting the balance. And this is a small thing, but I hear from people, Steve, that go to Italy and they say, I can't eat wheat in the United States. And then they go to Italy and they're fine. And you think it's that glyphosate? Yeah, they don't do that there. So if I tried, I'll try organic pasta tonight. And maybe that'll be better. Yes. And then like the alternative choice is, how do you do with bread?

12:31Dr. Will Bulsiewicz:Are you okay?

12:34Not all bread. Generally, I stay away from bread. Okay.

12:39Dr. Will Bulsiewicz:Do you ever eat sourdough? Yeah. Do you do okay with sourdough? Yeah. There we go. So here's the second part of this equation. Put the glyphosate, put that to the side for a moment. Let's talk about the fructans that we were talking about a moment ago. When you ferment your wheat, when you ferment your dough, you actually reduce the fructan content. What's fructan? So these are the long-chain carbohydrates that exist in wheat, barley, and rye. So if it contains gluten, it also contains these fructans. Like gluten is not the only thing in wheat, right? And these fructans, again, they're good for you.

13:14Dr. Will Bulsiewicz:They're good for your microbiome. But people who have a slightly damaged gut, they struggle to process and digest them. So this would explain why some people, they eat, you know, wheat-containing, gluten-containing foods, and they struggle. But they do okay with sourdough. Because if you ferment the bread, it reduces the fructan content, and actually then you can tolerate it. Oh, okay. So you think it might be the fructan in the bread that I have an issue with, and sourdough doesn't have fructan in it? Yeah, there was a study that was in gastroenterology a few years ago. Gastroenterology is the top journal in my field where basically they sent people home with a bunch of breakfast bars.

13:53Dr. Will Bulsiewicz:All right, not chocolate, but nonetheless, they sent people home with a bunch of breakfast bars, three of them. One of them was a placebo bar, so they didn't add anything special. One of them contained a very large concentration of gluten. And then the third one contained the fructans. and the placebo is our standard. We're going to compare to that. When people ate the gluten-containing bar, and these were, by the way, people that they did not have celiac disease. They did have gluten problems, according to them, right? So like, this is like the 20 % of people that you mentioned a moment ago who think they might have a gluten problem.

14:30Dr. Will Bulsiewicz:When they ate the gluten-containing bar, they actually had less symptoms than the placebo. So in other words, the gluten is not the problem. But when they ate the fructan-containing bar, they were triggered. So basically what this said is that we have been taking this concept of gluten intolerance, and we've misnamed it. It's not a gluten intolerance. It's a fructan intolerance. These are people who are tending to struggle with these particular parts of that food. What foods contain fructan? So wheat, barley, and rye. Okay. And there's many different types of fructans, by the way. So you may not react to all of them.

15:19Dr. Will Bulsiewicz:You may react to just some of them. But like garlic and onions are also classic. So you hear people who are like, I can't eat garlic. I feel it's horrible. Right? That can be a fructan issue. Teff, amaranth, sorghum, quinoa. These are whole grains that don't contain gluten. and they also don't contain fructans. How long does it take to repair the gut when you have done damage to it? That's a very broad question intentionally, but generally for the average person who's done, who's sort of irritated their gut, how long does it take to restore and for those microbes to go back? It really depends.

16:01Dr. Will Bulsiewicz:You have to start with, okay, what's your starting point, right? Like how deep is the damage? How bad is it? because for the people who have ulcerative colitis or Crohn's disease, those are forms of inflammatory bowel disease. Those people have the deepest dysbiosis. Dysbiosis is the word that we use for a damaged gut. Is it possible to reverse that? It's possible to put them into remission so deeply that they don't have a flare. Is that what the flare looks like on this little model that I have in front of me? Yes. So going back, for the people who are listening and not on YouTube, you can flip over to YouTube if you're interested.

16:39Dr. Will Bulsiewicz:But what I'm showing here is the model of the large intestine. And the model includes a little area that it looks raw, ulcerated. It's bleeding. If you were to bump up against it, you'll start to see blood coming out. So it's a very vulnerable, sensitive area. Now, these inflammatory bowel diseases, Steve, I have an interesting study on this topic. They are, to me, the classic gut inflammatory health condition. And what's happening is the immune system is attacking the microbiome. So technically, it's not actually autoimmune because autoimmune would be you're attacking your own body. The immune system is not attacking your intestines.

17:25Dr. Will Bulsiewicz:The immune system is attacking your microbiome and rejecting it. And because that's happening, your intestines are stuck in the middle. So this here is the immune system attacking the microbiome. It's attacking the microbiome, which is in the tube of the large intestine. And the immune system is trying to get at it and kill it. Why? And because it's decided that it's the enemy. So the immune system is confused because when we're born, we don't have much of a microbiome at birth. It's the closest that we will get to not really having anything. And then during the first three years of life, you build your microbiome through your life experience.

18:05Dr. Will Bulsiewicz:And by three years of age, you are basically fully adult-sized in terms of your microbiome. During this time, your immune system is learning from and with those microbes. So there's this interplay between the two that is undeniable, where when the microbiome is healthy during childhood, during those first three years, it results in a healthier immune system. So what's going on here? The immune system is supposed to acknowledge your microbiome as being friendly, and it does not. It decides that your microbiome is the enemy, and so it's taking it out. So what do you think is, for someone that has irritable bowel syndrome or Crohn's disease, or they have one of these big sort of ulcers in their small or large intestine, is it because of their lifestyle, typically?

18:56So lifestyle change or? Or is it lots of things? What's the number one perpetrator?

19:02Dr. Will Bulsiewicz:Okay. There's clearly a genetic component. Okay. So we have to be upfront about that. These are things that are not necessary within a person's control entirely. Because, I mean, there's no evolutionary reason why this would happen. There's no evolutionary reason why you'd have severe gut digestion problems. No, there's no advantage to it at all. And these things that occur, they were quite rare years ago. In fact, in third world countries today, there's not much inflammatory bowel disease. There's not a lot of Crohn's disease and ulcerative colitis in third world countries. If you go to Africa, there's very little.

19:40Dr. Will Bulsiewicz:And then what you see, though, is as countries industrialize, there's a takeoff and they start ramping up. So within the United States, over the course of 40 years, from 1970 to 2010, ulcerative colitis and Crohn's disease cases were increasing by up to 55%. And you can get that at any age? You get that at any age. Even if I'm healthy right now, I could do a set of things that would give me this. Yes. In fact, if you take, so back to our conversation about antibiotics, if you take antibiotics, your risk of developing an inflammatory bowel disease in the next year just doubled. Oh gosh. If you disrupt the gut with antibiotics, which the antibiotics do, there's nothing that will basically like decimate the gut faster, reducing gut diversity, disrupting the gut barrier by 50 % during a course of antibiotics and activating the immune system.

20:32Dr. Will Bulsiewicz:It really speaks to that, like if you take antibiotics, these risks of inflammatory health conditions really start to go up. We see this in both adults and kids. What you just listened to was a most replayed moment from a previous episode. If you want to listen to that full episode, I've linked it down below. Check the description. Thank you.

20:56from taco night in Tulum to sushi in Tokyo make every bite rewarding with gold from Amex wherever you dine four times membership rewards points at restaurants worldwide are piling up learn more at americanexpress.com slash explore-gold terms and points cap apply

From the publisher

Your gut symptoms might not be caused by gluten.

Dr Will Bulsiewicz is a leading gastroenterologist and gut health expert specialising in the microbiome, digestion and the science of food.

In this moment, Dr Will Bulsiewicz reveals why bloating, gas and constipation are often misunderstood, and why the real trigger behind your symptoms might not be gluten. Learn how your microbiome is quietly shaping your digestion, inflammation and long-term health. 

Listen to the full episode here!

Spotify: https://open.spotify.com/episode/32c3lvtL5rrQQiAs8QbJsW

Apple: https://g2ul0.app.link/WGPl0LtXB4b

Watch the Episodes On YouTube: ⁠⁠https://www.youtube.com/c/%20TheDiaryOfACEO/videos

Dr Will Bulsiewicz: https://theguthealthmd.com/

More from The Diary Of A CEO with Steven Bartlett

All 628 episodes
Most Replayed Moment: Are You Really Gluten Intolerant? It Could Be This Instead!The Diary Of A CEO with Steven Bartlett · 20 min
Listen in VO