Most Replayed Moment: The Fastest Way To Lose Fat Without Losing Muscle! - Dr Andy Galpin

30 Jan 2026 · 20 min · 8 chapters

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Podcast Episode Summary: The Diary Of A CEO - Most Replayed Moment: The Fastest Way To Lose Fat Without Losing Muscle! - Dr. Andy Galpin

Podcast Overview

  • Title: The Diary Of A CEO with Steven Bartlett
  • Host: Steven Bartlett
  • Guest: Dr. Andy Galpin
  • Description: Dr. Galpin, a performance scientist, discusses effective fat loss strategies while preserving muscle mass, avoiding common pitfalls like crash diets and excessive cardio.

Key Themes

Understanding Fat Loss

  • Broader Approach: Fat loss should focus on losing fat while preserving muscle and ensuring sustainable results.
  • Adherence is Key: Long-term success in fat loss is most significantly predicted by adherence to workout and nutrition programs.

Nutritional Strategies

  • Avoiding Dieting Mindset: Instead of viewing nutritional approaches as diets, adopt a flexible nutrition strategy that enhances adherence.
  • Personalization: Tailor nutritional intake based on individual triggers and preferences.
  • Protein Importance: Emphasize a high protein intake to maintain muscle mass during caloric deficits.

Exercise Considerations

  • Exercise Variety: There’s no single best exercise; preference and enjoyment are crucial for adherence.
  • Strength Training: At least weekly strength training is recommended to preserve muscle.
  • Flexibility in Workout Routines: Activities can vary widely (walking, swimming, etc.) based on personal preference.

Scientific Insights

  • Genetic Testing Limitations: Current genetic testing lacks broad validation across different ethnicities and backgrounds, making it less reliable.
  • Emerging Health Technologies:
  • Digital Twin Concept: The future of health monitoring may involve creating digital representations of individuals’ health to tailor interventions more effectively.

Challenges with Current Health Trends

  • Stress and Health: The historical pursuit of minimizing stress may have led to unintended health consequences.
  • Reintroducing Healthy Stress: Discusses the necessity of healthy stressors for personal growth and resilience.

Future of Health and Fitness

  • Precision Health: Advancements in technology may allow for more personalized health strategies, but significant ethical considerations and challenges remain.
  • Human Connection in Coaching: The value of personal trainers and coaches is emphasized, particularly as AI and technology become more prevalent in health and fitness.

Key Takeaways

  • Sustainable Fat Loss: Prioritize a balanced approach that combines enjoyable physical activity with a flexible nutritional strategy.
  • Personalization is Critical: Recognize that effective health interventions must consider individual differences in physiology and psychology.
  • Technological Evolution: New health technologies promise to enhance personalized care but require careful ethical consideration.
  • Community and Support: Personal connections in coaching and training are invaluable for motivation and accountability.

Conclusion The episode emphasizes a holistic view of fat loss that integrates nutrition, exercise, and technology while prioritizing individual preferences and psychological well-being. Dr. Galpin's insights encourage listeners to rethink traditional models of dieting and exercise, advocating for sustainable practices and personal engagement in health journeys.

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For more detailed insights, listeners can explore the full episode linked in the description.

Written by AI. May contain mistakes. Listen to the episode to check what was said.

Chapters

Tap a time to open that second in VO

Rethinking Fat Loss Strategies

0:45 to 2:49

Discussing common misconceptions about burning fat and the importance of preserving muscle.

“You can look across meta-analyses and review articles, and you will see the number one predictor of long-term successful weight loss, and by weight loss, I mean fat loss, is always adherence.”

The Importance of Adherence in Diets

2:49 to 6:00

Explaining how adherence is the key predictor of long-term weight loss success.

“But you got to do that in a way where you still are happy and...”

Personalizing Nutrition and Exercise

6:00 to 6:57

The need for individualized approaches to diet and exercise based on personal preferences and challenges.

“Maybe we'll play the game more with willpower.”

The Concept of Precision Nutrition

6:57 to 9:50

Exploring the future of precision nutrition and how it may help tailor diet and exercise plans.

“put themselves in a position of scarcity.”

Stress and Human Physiology

9:50 to 11:35

Discussing the effects of stress on human health and the importance of managing stress levels.

“so we'll see this in gait before we'll see this in symptoms.”

The Consequences of Stress Minimization

14:00 to 15:15

Explore the impact of removing stressors from our lives and the need for intentional stress.

“Now we have to go back and do this weird thing where we re-engineer stress back into our lives.”

Navigating Health Assessments and Data Challenges

15:16 to 17:24

Understand the complexities of health assessments and the lack of benchmarks for wellness.

“This is why the word consciousness is in the title of my book.”

The Role of Human Experts in Health and Fitness

17:25 to 19:32

Learn about the importance of human guidance in health interventions despite technological advancements.

“Where are we going to get these databases of super healthy people as the world continues to get less healthy?”
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Transcript

Automatic transcript. May contain errors.

0:03I've definitely grown up my whole life thinking that the way that you burn fat is by running. I mean this is what most people think right they think you want to burn fat around here the belly fat the best way to do is go for a run and a lot of people have very little luck with that and end up beating themselves up so to close off on this conversation I'd like to hear your take on that you need to think about fat loss in a broader approach than most people give it to which is to say when you say fat loss let's get specific what we're meaning is we're losing fat and ideally we're preserving muscle that's what that's what we typically want okay we're also talking about losing fat so that it stays off as long as possible those are baked in to that phrase but oftentimes forgot so the advice i'm going to give you is with those two assumptions in mind you're trying to keep as much lean mass as you can and you're trying to make this a successful journey and not something you have to repeat again time and time totally right yo-yo dieting in fact one of the more probably the highest most cited paper i've ever published was on yo-yo dieting like a review article on that so you can go read that people love that paper i was just a co-author um jackson wrote that paper um so credit goes to jackson for that um but making sure you're paying attention to say with those parameters in mind, how do I lose weight?

1:33You can look across meta-analyses and review articles, and you will see the number one predictor of long-term successful weight loss, and by weight loss, I mean fat loss, is always adherence. It's adherence to your workout program, and it's adherence to your nutrition program. So step number one, before we worry about any change in diet. We start arguing about which method of exercise is best before we start really going way down the line to things like genetic testing. You're really wasting your time here. And a lot of that stuff, especially if you're not paying attention to what's going to make you adhere the longest amount of time.

2:14In fact, if you just stopped right there, that's enough for most people. Can you put yourself in a position where you're able to feel abundant with your nutrition approach. And notice I'm trying not to say diet here, right? It should be a nutritional approach. You have a balance between living life and flexibility, but then also figuring out what triggers you. And maybe you don't have a trigger. Maybe you can be more flexible. Maybe you need more stringent, like all the things that go into it. You got to figure out a system. So you're not, people will not be on a diet very long collectively, right?

2:44On average diets don't work for those exact reasons, right? You got to get to a caloric deficit somehow. But you got to do that in a way where you still are happy and... Sustainable. Totally, right? And you still feel energy. And you're there and that it's working for you, right? And that's different for every physiology. Okay, great. And you got to meet the exercise system, the same thing, right? If you hate running, there's no reason, you don't have to run a step to lose a ton of weight. If you love running, you shouldn't run. If you hate lifting weight, fine. I can work with any parameter you give me.

3:17If all we're concerned about is preserving lean muscle mass and losing fat over the long term. That's really what we have to consider the most. Okay. Now within that, does that mean every training and nutrition program is the same? No, no, no, not at all. There are fundamental differences. Here's the problem to think about. If I said, hey, you're going to do the same training program the rest of your life, you'd probably be like, well, but if I told you that with nutrition, people are like, well, well, yeah, of course. Like there's, you know, magic diets that do, like, no. Keto, great. Mediterranean, great.

3:53High carb, great, great, great. You can do them all. They can all work for you. Some people taking out gluten helps. Some people go, great, great, great. Sure. All of it is possible, right? We come from very different backgrounds. If you look at any of the research, for example, like a really interesting point on genetic testing. if you're not taking account genetic background on that genetic testing for things like nutrition precision nutrition is entirely worthless because we see classic markers that are associated with say more effective carbohydrate utilization or fat utilization or or body composition and they might predict a decent percentage of variance in european caucasians you apply those exact same things to a West African or East African, and those variants go to zero.

4:43People forget that part when they start talking genetic testing. They have not been validated across all ethnic backgrounds. The ones that have, have shown they range from like 40 % variance to zero. So like really, like you're way, way, way ahead of the cart here, paying attention to things that just do not matter. We got to get you on a system that works. Okay, great. for some people that might be more nutritionally based all right you can lose and preserve muscle mass really well by just going decently high on protein and then regulating your calories the example i gave you earlier you want to go more carbs less fat great you want to the opposite like we can play those levers no problem all right what's your problem though oh i struggle with um cravings okay great oh i struggle with hunger pangs okay great i struggle with okay well then we're going to make those decisions based on more of this, more based on like, where's your pain point?

5:36What's your problem? I struggle with the, okay, great. I have to, now we're personalizing, now we're individualizing it based on things that are going to matter orders of magnitude more than other things that I've just talked about, right? That stuff will trumpet. Exercise is the same thing. Maybe you hate exercise. Okay, great. Maybe we can get you to walk a few times a day and we'll get most of our fat loss through our nutrition. Maybe the opposite. You love training, but man, you just struggle to eat whatever or not eat something. All right, great. Maybe we'll play the game more with willpower.

6:06We'll push the pace on our exercise. High intensity, fine. Low intensity, fine. Weights, great. Cardios, great. Surfing, great. Don't zone six, I don't care. All of it can be done. Some of the foundational things that tend to be consistent for those two things on most people is you need to make sure protein is adequate. hard to maintain muscle mass with lower protein, especially if we're going hypocaloric. So keep protein high. You want to do something revolving strength training at least once a week for the same exact reasons, something that makes you burn a lot of calories, long duration, high intensity, either way, that's all you really have to do.

6:51If you can do that stuff consistently, over time, you're going to get there. You're going to be just fine. Where we see problems are people that put themselves in a position of scarcity. What do you mean by scarcity for anyone that doesn't know? Depriving themselves of something. You feel like you never get to do the thing you want to do. And this is a psychological thing, right? Totally. Which causes the yo-yo effect. Which causes the problem of consistency and adherence over time, right? So making sure you do that. I personally have some go-to standards I like to do. I'll happily share that with you.

7:24I tend to like to have a decent balance between kind of our anaerobic strength training, high heart rate stuff, and our more steady state, longer duration stuff. So if someone's gonna be able to work out three times per week, I'm probably doing one thing where we're going long duration, call it a hike, call it a swim, call it a run, whatever we can do. And then the other two days, I'm probably doing a combination of lifting and then probably finishing with some high heart rate thing, right? So we'll do like a little bit of strength and hypertrophy, muscle growth work, and then we'll do a circuit or an aerosol bike or some sprints or like what can we get you into?

8:00It's like really, really hard. If I can get you in an environment where you're working out with some other human, I love that. Is there any reason why you do the strength first and then? Absolutely. That's a great question. If you do strength training before endurance work, your strength training will not compromise your endurance. In fact, sometimes it exacerbates it. If you do your endurance first, you're going to be more fatigued and you're going to lose strength and still have worse performance in your strength training. What's the most important thing we haven't spoken about? You know, if there was one more thing you could add of all the things you know that would allow Jennifer, who's a 34-year-old single mother, or Dave, who's a black cab driver in London, the average person.

8:45I think it is exciting what's coming in the world of human health. And I think it's helpful for people to know that stuff because a lot of the challenges we're facing are going to get worse. We have things that are going to be possible pretty soon. Kind of the stuff I'm talking about, this idea of precision exercise, precision nutrition. It's not really available to many people, too expensive, etc. We're going to cross those barriers pretty soon. We are working on a project right now called the Human Digital Twin. So this is a combination of a couple of my companies. So the sleep company, Absent Rest, our blood work company, Vitality Blueprint, Springbok.

9:33There's another company called AxioForce that actually has four sensors in your shoe. And we can see early changes potentially in gait. So how you're walking, which could potentially, and research is needed here, but potentially be early signs of Parkinson's development, neurological disorders. so we'll see this in gait before we'll see this in symptoms. Companies that are involved in this entire thing, we can take all those data, we're actually doing this right now, put them together and make what's called a digital twin. This allows us to make your physiology, and so from our perspective of vitality, we've got all your blood work and molecular biomarkers.

10:12From absolute rest, we've got your sleep. We've got your movement patterns. We can actually work with another company to watch you physically move and do that stuff. We can take your physiology and upload it. Then from there, we can run endless simulations of combinations of nutrition and training and supplementation, medicine, movement, daytime patterns, sunlight, water, all those things, and figure out really quickly how you're going to respond the best for whatever outcome we want. It's not ready at all right now. But we're actually, again, running it right now. We'll have our first cohort done probably in the next week or so.

10:47Yeah, really, really soon. I don't know how well the model is going to be the first time through it. I don't know if our group's going to be the best at it. It doesn't matter. But this is clearly going to be something the world is capable of. As we get better at being human sensors and we can bring those data in, we're going to be able to deploy things like this and say, hey, yo, this is most likely to work for you. The digital twin is already being used for like the heart. It's in place. We have the digital twin of the kidneys is as well. The lungs are coming soon. The heart is coming pretty soon.

11:19There's lots of groups. I'm not involved in any of those projects, but that's, it's coming on board. So the ability to not have to guess anymore and most importantly, try. I tried this for six weeks. It didn't work. I tried this for nine. That's going to go away really fast. Great. You still have to go do all the work. The technology won't work out for you. Well, we have some stuff that'll do that too. what's the cost though? like when you were saying all of that I go do you know what I mean? we spent the entire length of human history with one maybe arguably two singular goals one of them at the core was stress reduction that was what we're after right?

12:03you create communities so you're safer you create homes so you're environmental you create agriculture so our food and we all wanted to reduce the stress thing right? we didn't call that but that's what it was And then we got to the year 2000 or so, and we realized, oh, fuck. Maybe that was the wrong target. I saw on your bookshelf at home, there's a book called The Comfort Crisis. Oh, yeah. And that just flashed in front of me as you were saying that. Yeah, shut up. Michael, it's a great book. When we have astronauts come back from the International Space Station, getting people to live on Mars, it's a bit of a rocket problem, but it's a bigger physiology problem.

12:45and this HDT project where one is part of the people we're working with is Cody Burkhardt who runs human works at NASA figuring out that line of going hey you don't want to release stress if you do like what happens when we send people up to space because there's no gravity your physiology tanks really quickly right they come back often times astronauts come back and they can't physically walk for a few days because in that case, that aspect. Now, other aspects of stress are way up. We've lost some of the core tenets that it means to be human, and we are not ready for that. We are not ready at all to be able to be told, oh, yeah, run this scan, and here's the exact culmination of life you need to run.

13:31Not even counting the ethics behind all that. The ethics of genetic testing alone are really, really interesting to say the least.

13:43The ethics of doing something like that, we have not thought through this stuff. Collectively, we. There is more in our world and our human experience than just straight answers. This is one of the beauties of this ride we get to take.

14:05I don't know if we have good answers I think we've clearly shown we're not very good at asking those questions before because the incentives in the short term are so tempting we're seeing this with AI at the moment it's just so tempting and then we get the results back in 20 years and by then it's just too late I mean look at the current health position that we're in we went after that entire idea of minimizing as many stressors as we possibly could. And uh-oh, it worked. Yeah. Oops. Now we have to go back and do this weird thing where we re-engineer stress back into our lives. You have to be very careful and judicious when you pull things out of a natural state.

14:54I'm being very choosy with my words there. If you're not directing stress, you're letting something else to wreck that. That stress is still coming one way or the other, which means adaptation is coming. So you can be intentional and point that ship in one direction, or you can cover your eyes and think it's not happening at all and realize you're getting pointed somewhere else. It's better to at least have the acknowledgement. This is why the word consciousness is in the title of my book. This is part of the process, right? You can be aware of it, or you cannot, from there you can choose whatever you want.

15:33That's entirely up to you and all that. I just want people to realize you're making a choice one way or the other. So when you involve technology into the picture, AI is another really, really challenging thing in a lot of ways. But I'll reiterate, we've seen this already play out and we know the answer is this gets worse in terms of we're not going to make very good choices right away. how does that manifest itself in the end? I don't know. Nobody knows. But to date, we're not particularly good at making that decision. So there's lots of consequences there. I think that we have there. One of the last things I'll say on this is if you break down, okay, the way that we structured is there's four pieces, okay?

16:23In order for you to have more success at your performance and health. You, number one, have to have assessment. Once you have all this data, you have to go to step number two, which is then you have to qualify. Good, bad, great, worst ever, best in world history, okay? We're struggling on that. We don't know what healthy it looks like. I know what clinically deficient rickets looks like. I know what obesity and type two diabetes, and we know disease. We don't know what good versus great means. There are no databases I can pull from. There is no metric I can look at and say, what is a great, what's a great vertical jump number?

16:59What does somebody need to be able to jump in their 40s to be healthy? Like, we don't know these things and I don't know it by ethnicity. And I mentioned that before, that's a critical component because it is clearly different, right? There are some markers in basic blood chemistry that are not different in Southeast Asians or that are different in Southeast Asians versus Northern Europeans. Like, we don't have that fully fleshed out. And if we do, it's for disease markers. We don't have the data. So I don't even know what I'm judging. Okay. Now, assessment, great. Where are we going to get these databases of super healthy people as the world continues to get less healthy?

17:34I'm losing my population to pull from really, really quickly, okay? Then the next piece is, okay, great. You've told me that this marker should be here. Pick your marker, whatever you want. How do I get it there? And that's really where we're struggling. So the second problem is what I call Polaris. We have no North Star. We don't know where this thing should go. The third one is, okay, how do I get there? What is the intervention? What is the thing? That's where I actually think people in my field are going to not only maintain, but increase their value, such as like personal coaches, physical therapists, athletic trainers, people that are gonna, nurses.

18:14Because you might have an AI that can come in and run something and say, great, your numbers are here and our metrics say you should be here and then you should go do X. I want somebody there with me. I want a human taking me through X. That's going to feel better because we don't know. There's almost no data on, okay, great. Well, what is the optimal training for that marker? What is the optimal nutrition? That is really, really limited. So we have to rely on expert. We have to rely on people that go, I know the evidence base, but then also my experience, I'm thinking about this this way. If you were an NFL quarterback and you tore your ACL and we ran all that stuff on you, you would still come back and go, oh great, there's a coach over there who's actually run people through ACL recoveries on 15 starting NFL quarterbacks.

19:04Like what's it gonna cost? You're hiring that person, right? Cause like you've done it before. Fantastic. Like the budget doesn't matter at that point because the person's actually done it and they will be there. Fantastic. I really feel like our field is gonna increase in the value because of that. They're going to want to say, okay, awesome. The numbers came out on this. The AI told me this, this, this, there. You've done it before, yeah? Done it a lot? Great. I trust you the most. I want you by my side. I want that companionship. As we lose more and more connection to other people, it's my biased opinion in my field that this is a great place where people want someone there.

19:43Online coaching is great. That's fine and all that. But you're seeing actually already a premium coming on like, I want to hire an in-person trainer. can you give me that person? Where like the boom was the opposite for a while and now it's already swinging back where people would rather have somebody there in person for all those reasons. So that is, I think, an incredibly interesting challenge. But that's the way to think about it. That top one's going to get better, lots of problems. But what are we comparing against? And then what do we do about it? That's going to be the real trick. What you just listened to was a most replayed moment from a previous episode.

20:19If you want to listen to that full episode, I've linked it down below. Check the description. Thank you.

From the publisher

Dr. Andy Galpin is a professor and performance scientist with a PhD in Human Bioenergetics. He specialises in muscle, strength, and human performance - translating exercise science into practical plans that actually work. In today’s Moments episode, Andy explains the fastest way to lose fat while preserving muscle - without falling into the crash-diet, over-cardio trap!

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Dr. Andy Galpin: https://www.andygalpin.com/

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