In short
Acid reflux (including “silent” reflux) and its root causes; how to reduce reflux risk and prevent downstream damage like esophagitis, Barrett’s esophagus, and esophageal cancer.
Guests
Dr. Darrell Joffrey (celebrity nutritionist; has written multiple books; runs a men-focused, root-cause practice; describes personal sugar addiction and a family tragedy—his father died of esophageal cancer after being told it was caused by “too much acid”). Host guests are Matt Rogers and Bowen Yang from Las Culturistas (comedy/health-adjacent podcast hosts).
Key claims
Reflux is usually driven by low stomach acid leading to poor digestion, fermentation, pressure, and a weakened lower esophageal sphincter (a muscle), not “too much acid.” Men face higher esophageal cancer incidence. Lifestyle “three-hour rule” (no eating within 3 hours of sleep), stress reduction, avoiding ultra-processed/acidic foods, and magnesium to strengthen the sphincter are emphasized.
Notable examples
coffee and alcohol relaxing the sphincter; Cialis/tadalafil causing reflux; H. pylori linked to low acid; slippery elm tea, local honey + propolis, diluted apple cider vinegar, and “neutralizing” coffee powder; gluten as a gut “weapon of mass destruction” via zonulin/leaky gut and even “gluten-free” foods potentially containing other harmful proteins.
Written by AI. May contain mistakes. Listen to the episode to check what was said.
Chapters
Tap a time to open that second in VODr. Drafri's Journey to Gut Health
3:38 to 5:04
Understand Dr. Drafri's personal and professional journey in gut health.
“Joffrey has been in the business for quite some time.”
The Impact of Acid Reflux
5:04 to 10:46
Explore the causes and implications of acid reflux, informed by Dr. Drafri's experiences.
“And the more people we can help get to that root cause, people are going to start to do better.”
Root Causes of Digestive Issues
10:46 to 11:40
Learn about the misconceptions regarding stomach acid and digestive health.
“I mean, 60 million Americans are suffering this once a month, 25 million Americans every single day.”
Men's Health and Reflux Risks
11:40 to 14:05
Discuss the unique risks and challenges men face regarding acid reflux and health.
“I'm going to give you this prescription.”
Understanding Acid Reflux in Men
14:05 to 15:00
Learn why acid reflux is particularly harmful to men and its associations with esophageal cancer.
“Well, it's interesting when we talk about men, because obviously we want to help as many men as possible.”
The Role of Stress and Diet
15:00 to 16:18
Explore how stress, diet, and lifestyle contribute to acid reflux symptoms in men.
“One of the worst things that men do is they eat late night snack.”
Symptoms and Consequences of Acid Reflux
16:18 to 17:20
Identify the different symptoms caused by acid reflux and their potential complications.
“That gate, that basically should be like a dam.”
Barrett's Esophagus: A Serious Condition
17:20 to 18:15
Understand Barrett's esophagus and its risks, including progression to cancer.
“It shows us many other things, but we have to understand if we go further downstream into that gut, it's really that lower esophageal sphincter that's weak and that needs to be fixed and strengthened.”
The Importance of Magnesium
18:15 to 19:18
Discover the critical role of magnesium in digestion and its impact on acid reflux.
“bad, but it can happen really to anybody that has any kind of digestive disorder.”
How Magnesium Affects Esophageal Health
19:18 to 21:03
Learn how magnesium supports muscle function in the lower esophageal sphincter.
“And so talk to me about, A, why we're deficient in it?”
Show all 29 chapters
Inflammation: A Key Issue
21:03 to 22:34
Explore how chronic inflammation contributes to the severity of acid reflux symptoms.
“So when that acid reflux is up the wrong way into that esophagus, the lining of the esophagus was never meant to take on that bombardment of acid because think about this from a common sense standpoint, guys.”
Taking Acid Reflux Seriously
22:34 to 23:02
Understand the importance of addressing acid reflux before it leads to severe consequences.
“So again, this is a very serious problem.”
Addressing Sugar Addiction
25:06 to 28:00
Learn about the impact of sugar addiction on health and alternatives to manage it.
“You can literally type any prompt and put the AI to work.”
Understanding Sugar Addiction
28:00 to 28:54
Learn about the addictive nature of sugar and its effects on the body.
“You know, bestselling author, multiple books, such a wealth of information.”
Shifting to Healthier Eating Habits
28:54 to 29:41
Discover how to modify your diet to reduce acid reflux and sugar cravings.
“I mean, sugar pumps up your dopamine eight times more than cocaine, which is actually one of the craziest stats I've ever heard.”
Managing Coffee Consumption
29:41 to 31:00
Find out how to enjoy coffee without worsening acid reflux.
“But PPIs are never meant to be taken for more than 14 days.”
Alcohol and Its Effects on Acid Reflux
31:40 to 33:41
Understand the impact of alcohol on acid reflux and which options are better.
“Well, I was going to say, we have a segment that this goes right into for all of my guests called, am I going to be okay?”
Insights on Gluten and Gut Health
33:41 to 35:53
Delve into the relationship between gluten and various gut health issues.
“alcohol, if you're going to go this route, guys, is going to be something like a gin, a grain-free vodka, or a tequila.”
Effects of Gluten on the Body
35:53 to 42:00
Learn about gluten's role as a gut irritant and its broader implications for health.
“propolis in that honey which you can get from a local honey producer propolis has incredible um healing effects to the esophagus and the stomach lining.”
Understanding Gluten and the Gut-Brain Connection
42:00 to 43:00
Explore the impact of gluten and other proteins on gut health and mental well-being.
“glands that gets hit by leaky gut, the liver, and of course the brain.”
The Myth of Gluten-Free Foods
43:00 to 44:10
Discover why gluten-free products might not be as healthy as believed.
“And that avenin is going to cause the same destruction in the gut that gluten will.”
The Role of Fats in Our Diet
44:10 to 45:50
Learn about the difference between healthy and unhealthy fats and their effects on health.
“People look at gluten and gluten-free products as healthy because they're like, gluten-free, gluten is killing me, but they're replacing with things that are going to kill them just as fast anyway.”
The Impact of Seed Oils on Health
45:50 to 47:55
Understand how seed oils contribute to inflammation and health issues.
“And so what you're trying, what you're doing is it's all, and I think you do such a good job of talking about this in, in, in your books and in your talks about everything in moderation.”
Autoimmune Diseases and Gut Health
47:55 to 50:50
Examine the connection between gut health and autoimmune diseases.
“Epigenetics means that we can actually change gene expression by how we eat, how we think, and how we move.”
Steps to Heal Your Gut
50:50 to 52:25
Learn actionable steps to improve gut health and overall wellness.
“And I think you touched on, you know, we sometimes call it the two hit hypothesis that you have this predisposition, genetic, whatever we want to say that has an innate predisposition to something.”
Dr. Darrell's Morning Routine
56:16 to 58:40
Discover Dr. Darrell's essential morning practices for gratitude and health.
“I just got chills when you say that because this is my kind of morning routine.”
Sugar Detox Insights
58:40 to 1:02:08
Hear expert advice on overcoming sugar cravings and the importance of purpose.
“I mean, you hit me there with the message of gratitude and all we have to be thankful for.”
Healthy Alternatives to Sugar
1:02:08 to 1:04:58
Learn practical tips for healthier snacks and overcoming cravings.
“five minutes, 10 minutes, 20 minutes, and just start to write out, like, what is your purpose in life?”
Final Thoughts and Gratitude
1:04:58 to 1:06:27
Wrap up with reflections on the discussion and appreciation for the guest.
“Like something that stimulates you and makes you happy because it's all about peak state.”
Transcript
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3:04Mills back with a fantastic another episode of The Mailroom. Just coming off that amazing intro from our boys at Long Transit. Jordan, my indomitable, inimitable, and indecatable host is with us. And I know I get pumped up about every episode, but I got to say, I think both of us were super pumped when Dr. Joe Drafri decided to join us. Just because obviously his reputation in the sphere is something. And, you know, if I read your whole intro, we would have absolutely no time to actually get to the stuff. But let's try. So Dr. Joffrey has been in the business for quite some time. He has written multiple, multiple books, has been on TV more times than I can imagine.
3:46He is a true celebrity nutritionist in all the right forms of it. In other words, he and I speak the same language of empowering men to do better themselves and then using the healthcare profession as a way to almost set up a coaching-like establishment. So it's not about, you're not going to go to him and he's going to say, here, I'm going to write your prescription. You're going to take this. That's all you need to do. Otherwise, go back, sit on your couch and let the medicine do the job. That's not what he's into. He's not into quick fixes. And he has a personal interest, really personal interest, which I'm hoping we'll get into with acid reflux and the scourge that causes the American diet, the American male.
4:27And with that, I mean, I just want to get after this because, man, it is such an honor to have you on the show. And I'm super excited for a couple of reasons. One, because we are both, I think, have this amazing passion for taking care of guys. But we do it from a totally different perspective. Your specialty is different than mine, but it also, the homology is the same. And that is that it's all about patient and man empowerment. So welcome, man. Yeah, thank you, guys. So good to see you. And And just a blessing to be here to share whatever I've learned over the years through my own personal struggles, you know, with health and overcoming those.
5:02But I think you nailed it. It's all about root cause. That's what we got to get to. And the more people we can help get to that root cause, people are going to start to do better. So, you know, I love creation stories, Daryl. And so tell me what got you into your field. Tell me what gets you up, motivates you every day to keep doing better and to keep looking for how to improve not only your life, but the lives of the men that you treat. Yeah, I mean, it goes all the way back to 2004 when I started practice in New York City. And, you know, it's amazing to have this practice because you got to really see this very small group of people that were high energy.
5:38They had like flawless skin. they look so much younger than their true biological or chronological age and they were just doing all the right things then you had everybody else which by the way I was lumped in right we were the yo-yo syndrome we had days where we felt good days where we felt awful more those days than the other but you know I really used my practice as this kind of little micro lens to see what the people that were really living health and having true energy which is I think the best way to describe health how is your energy doing and I just started to just to study them. And what were they doing?
6:09What were they not doing? Because for me, I had a massive sugar addiction. I mean, I coached thousands of people through sugar addiction. I hate to say it, but I probably had the worst sugar addiction of anybody that I coached. It was that bag. And, you know, one thing you'd have to know about sugar, it's a drug. I mean, it's become America's drug of choice. So throughout the years, you know, I had a chiropractic practice. I really became, you know, interested in nutrition and how to really strengthen the body from the inside out. but everything changed in 2014. It was one week before the New York City Marathon, one of my favorite days in New York City.
6:39I've been wanting to run the marathon, guys, for about 20 years. It was like the granddaddy, right, next to the Boston Marathon. And here I am in my final training run in Central Park, and I'm just kind of walking by, you know, the stands that were empty, envisioning that day a week from now, and the stands will be packed. As I cross that finish line, my wife's going to be there with my six-month-old son, Braden, and my parents, my mom and dad, We're driving down from New York because they never missed a soccer game when I was at Boston College, and they were going to come watch me run this race.
7:08And then as I'm running, all of a sudden, my phone starts to vibrate. So I lean down, take my phone out as I'm running, see a missed call from my brother Brandon. So I take a ridiculous selfie, send it back to him, keep on going. Seconds later, phone starts to vibrate again. Take it out. Says, call, emergency. And immediately, guys, I knew something happened to my mom and dad who were driving down from Vermont. And I'm not sure if you're familiar with the Northeast at all, but they were in Hartford, one of the busiest highways in America. And they're in the HOV lane of 91 South. And my mom was always the passenger and my dad was always the driver.
7:42And all of a sudden she's knitting a sweater for my son, Braden, who she was going to see in a few days as she feels the car starting to veer off to the left. Well, there's one big problem, guys. a concrete divider driving 70 miles per hour as she looks over at my father and he is literally eyes closed passed out against the window like this so instantly takes over she literally the car goes up the concrete divider she leans over grabs his leg off of the accelerator pulls it off car comes back down goes back up as she pulls the keys out of the ignition as the car crashes and now i find myself in a car driving up to the hartford hospital and all along the way guys as a doctor, I'm trying to think to myself, what's going on here?
8:23What was the cause? Was it a heart attack? Was it a stroke? Was it an aneurysm? And as I get to the hospital, I speak to the doctor. The doctor says, no, your dad has esophageal cancer. I'm like, what? Esophageal cancer? You're kidding. So three days later, we meet with the top doctor in Slogan-Kettering in New York, just a few blocks away from where I live. And he's the top specialist in esophageal cancer. and he proceeds to tell us that things like this are usually caught later. So the good news is that it hasn't spread yet. So that was the first sigh of relief. The second thing he says is that things like this are usually caused by too much acid in the stomach.
8:59Let's hold that thought for a second, guys. So as a doctor, I just literally start to double down, you know, like any good investigator does. We follow the evidence and I start calling every specialist or reading as many studies as I can to really figure out what happened. Why did my dad get this? Why did we ever or never notice that dry hacking cough that he had? And most important, what can we do to actually try to reverse this? So as a result of that, I became a gut specialist. Now, I thought I was a gut specialist at the time, but no. I learned over these next couple of years that what it really took to become a gut specialist as I tried to help my father.
9:33So fast forward three years later, after the accident, I'm driving up to Connecticut just to see my father and the rest of my family. It was my birthday, so it was a fun celebration. Now my daughter was born and she's a few months old and we get to the house and I'm seeing my dad there. Guys, he didn't look good. He lost a ton of weight. He just had no energy. You can tell that he was losing the fight. But we had a beautiful day, had some really good quality time. Went back to the city with my family. Literally two hours later, I get a call from my brother saying, Daryl, you got to come up to Hartford right now.
10:05Dad's in the hospital in a coma on life support. So now I'm on my way up to the hospital. I get there. I'm holding my dad's hand. He's got a tube down his throat. We're all around him at the hospital. And that's when I made a vow to my dad. And I said, dad, I'm so sorry. I couldn't save your life. I'm so sorry that I couldn't do more. But I promise I'm going to do everything that I can to prevent as many people from suffering the way that you did. And right then they pulled the plug and he died. So, guys, it was a tough moment for me. but I look back, there's blessings in every moment. And this is why I'm here today.
10:40So thank you for having me on to tell my story. Because the core of what I do is acid reflux, silent acid reflux. It's an epidemic. I mean, 60 million Americans are suffering this once a month, 25 million Americans every single day. And it's literally a silent killer. So it's my goal. If I could help one person deal with this issue and help them get through it, this is worth all of time. Well, Daryl, I mean, boy, that is a hell of a creation story. I think, you know, my creation story in 30 seconds was I watched a perfect stranger die when I was studying abroad. And I thought, you know, I can think of how many people can help.
11:16This guy died in a trauma, but that was my trigger. But to have such a personal story about your own dad passing and how that really changed the trajectory of your career, just again, it goes to your dedication. And yeah, I think we're going to really get into what you can do. But the thing that really excites me about your approach is that you're not saying, I assume you're at least not going to say, I won't put words in your mouth, but you're not saying, okay, here's how, here's how it's going to go. I'm going to give you this prescription. I'm going to make all your reflux go away. So you don't have to do anything.
11:47Right. And you know, how many guys walk into both of our offices every day, you know, they're like, yeah, I'm glad I'm here. Look, like for me, it's, it's testosterone, right? Everybody wants testosterone. They don't want to hear about weight loss always, and they don't want to hear about exercise. They want to hear about empowerment. But they are going to hear about that for me before I start talking about what prescriptions that I can write. And so that's what I want from you is I want you to unpack it for me. And I love what you said, too, about it's all about acid in the stomach. Because, you know, what I remember, the pH in a normal stomach is like 1.5 to 3, right?
12:20It's pretty. And it's there for a reason. And acid in our stomach is what makes sure we don't die of E. coli every time we eat a breakfast burrito, right? That's right. And by the way, doc, this is where my dad's doctor got it wrong. Because if you look at the root cause of acid reflux, contrary to what our common sense might think, it's not too much acid in the stomach. It's too little acid. And that's the key difference. Because you have to understand that as we get older, we don't get stronger. We get a little weaker. We don't get faster. We get a little slower. We don't produce more acid. We produce less.
12:50That's right. And the problem with that is it sets up this kind of slew of issues downstream where we have poor digestion. Because of that, the foods start to ferment and pressure builds up. And now the problem is not the acid. The problem is that the acid goes up the wrong way through that gate that needs to be closed. Right. Yeah. And that gate you're talking about is the lower esophageal sphincter, which is a muscle. Something I'm interested in because I do prescribe. And I think one of the longevity drugs that has really good track records for cardiovascular health, for cerebrovascular health, and for sexual health, which is my specialty, is the phosphodiesterase inhibitors.
13:28But the problem with those drugs is that it does cause reflux, right? So if I put a guy on Cialis, which is Tadalafil, the generic name, great profile. It's a revolutionary medication. But the number of guys, in fact, I just saw somebody early this morning before I tuned in here that said, I can't take it. You know, every time I do it, I get heartburn. So, yeah, let's walk through a little. You kind of hit on it, but just walk me through the physiology of how we keep the acid in the gut where it's supposed to be. What can we do from a lifestyle perspective? What can we do from a non-prescription perspective to make this better?
14:05Well, it's interesting when we talk about men, because obviously we want to help as many men as possible. Acid reflux is something that affects both men and women significantly. I mean, I would say it's probably about 90 % of my practice right now, people coming to me. You know, other things, bloating and digestion and other forms of autoimmune issues. But with men, it's actually a lot more damaging and dangerous. I mean, the research shows that men have about a five times increase in the incidence of esophageal cancer, which my dad passed from. Barrett's esophagus and other forms of esophageal inflammation.
14:38And there's a lot of different reasons for that. But I think one of the reasons that a lot of us men, we live in a pressure cooker. It's like we have chronic stress. I'm not saying that women don't have that, but we typically are marinating in our cortisol, which is our stress hormone. Many men have a diet high in ultra processed foods, which is obviously very acidic, inflammatory to the gut, creases, lots of oxidative stress. We have poor sleep. One of the worst things that men do is they eat late night snack. I mean, one of the most important things that you can do to shift reflux is what's called the three-hour rule, where you're not eating basically three hours before you go to sleep, between sleep and that mealtime.
15:13Because remember, sleep is about proper sleep. It's not about digestion. And when we are actually eating food, the acid is going to increase in the gut, albeit low levels of acid. And then when we lay down, what happens is that acid will go up the gate the wrong way. And ultimately, it's the gate that we have to talk about because the reality is I've never met anyone, men or women, that have too much acid in their stomach. It's always low acid, right? And one of the big things that low acid does, as I just mentioned before, is that we can't digest our food. One of the things I always say is that you're not what you eat.
15:45You're what you digest, absorb, and assimilate. So if we're eating food, whether those foods are good or bad, and we're not digesting that food, those foods just get stuck. It's like a traffic jam. And when they actually have that traffic jam, the bacteria in the stomach and to some degree the small intestine begin to ferment that food. And that creates gas. That creates pressure. So even though there's lower levels of acid in the stomach, it's that pressure like a balloon. Imagine like a balloon just blowing up. It's going to push all of that acid that's in there up the gate the wrong way. And then what happens is most of us have a weakened lower esophageal sphincter, as you mentioned before.
16:22That gate, that basically should be like a dam. So when we eat, that dam should open up, it should let the food in, and that dam should close so that digestion could actually happen. But what happens with most people with acid reflux is that becomes weakened mostly because of a magnesium deficiency, which is why minerals and magnesium, one of the most important supplements that we can actually take to start to help this process. But what happens now is because that blood gate is now weakened, that acid and that pressure goes up the wrong way into the esophagus, into the throat, causing those classic symptoms like chest burn, heart burn, throat burn, which is something that I had years ago.
16:57I had severe mold issues while I was actually out in California, Newport Beach living, and it created a significant form of acid reflux. For me, it emanated in my throat. Many patients, they get ulcers, they get ulcers in the mouth. So again, it can even go up all the way into the sinuses. We see chronic sinus congestion. We even see ear pain. So the symptoms for silent reflux aren't the typical symptoms that most of us think about, which is that kind of burning in the chest. It shows us many other things, but we have to understand if we go further downstream into that gut, it's really that lower esophageal sphincter that's weak and that needs to be fixed and strengthened.
17:32Yeah. Yeah. And I think when we see fluids that aren't supposed to be where they're supposed to be, then the cell type changes, it goes through what we call a metaplasia, squamous metaplasia. I think you talked about Barrett's esophagus earlier, which is exactly that. It's where the gut material goes up into the esophagus and instead of having a natural healthy esophageal lining, you end up metaplaging and the cells change. And a certain percentage of those, I think it's around 10 % or so, if I remember from medical school, of guys with Barrett's will go on to full-blown esophageal cancer. And it all starts really with what you're saying is not some necessarily genetic cause, but a lifestyle cause, poor digestion.
18:12Certainly we know cigarette smoking, alcohol combined are bad, but it can happen really to anybody that has any kind of digestive disorder. And, and well, man, I got to say, first of all, we got to take a pause to say, this is a radio thing, but if you could see how passionate Dr. Darrell is right now with his, his arms failing as he's explaining all this, it's so gratifying to see somebody that's so invested in the health of everybody that's listening today. So, so I love it. I just, you know, I wish we could bottle that enthusiasm. It's the Italian in me. Gotta use the hands. The passion. I'm so excited.
18:46But you said two key things. I mean, I'm big on take homes. And I think, you know, we haven't even gotten to that segment yet. But the take homes here are that we're eating too close to bedtime. So the three hour world. And then I was going to get into supplements. And I think we'll transition a little bit over into into what we can do outside of just better diet, which it sounds like probably eating no processed foods easier said than done, as we know, but also just decreasing the amount of calories we eat at one time. so we're not dumping everything into our gut. And then, so unpack the magnesium for me.
19:17How does that work? Because that's coming up in sleep medicine a lot. That's coming up in digestion and mood. And so talk to me about, A, why we're deficient in it? Why do I need to take a magnesium supplement? Do I need to take one if I have a good diet? And just kind of walk me through that, Dr. Darrell. Yeah, I love that question. I mean, there's five big supplements that everybody really should be taking. My children who are now 8 and 11, my mom who's 78 now, and adults like us. and I talk about this in both of the books, number one, magnesium. I mean, it's the fourth most abundant mineral in the body, yet it's probably the most important for the brain because it's the number one neuroprotector of the brain.
19:53I mean, you know this, it's responsible for over a thousand different enzyme reactions in the body, but we are massively deficient, one, because we're just not getting it from the foods that we eat because the soils become depleted. That's a whole other story. We look at pesticides, herbicides, fungicides, glyphosate. The animals that we're eating are deficient as well. And on top of that, most of us are addicted to sugar, you know, and it takes about 54 molecules of magnesium to neutralize one molecule of sugar. So if we are literally bombarding and pumping up our bodies with sugar, sugar, sugar, crappy carbohydrates, we are literally burning away at our magnesium levels.
20:29And by the way, historically, men do burn through magnesium faster than women do. So you also have to look at like when someone gets like a back injury, what do we tell them to take? All right. Yeah. Take an Epsom salts bath. Let's get the pressure off the nerves, but let's also take some magnesium because magnesium helps the muscle to restore its function. And as you mentioned, that valve between the esophagus and the stomach is a muscle. So just like you get a muscle knot in your back, that can go into like a little spasm and become weaker. Magnesium helps that. It helps strengthen that muscle, helps that muscle restore to its optimal function.
21:02The same holds true for the actual lower esophageal sphincter. It's a muscle. So magnesium and other minerals are very calming, suiting to the upper GI tract, but they also help to strengthen that valve and get it back to function, which is critical because you were talking about when that acid goes the wrong way in baris esophagus, the first stage, because acid was designed for the stomach tissue. It wasn't designed for the esophagus. It's a completely different lining. So when that acid reflux is up the wrong way into that esophagus, the lining of the esophagus was never meant to take on that bombardment of acid because think about this from a common sense standpoint, guys.
21:36Acid is corrosive. I mean, it could burn a hole through metal for all we know, right? So think about what that does to that tissue. It is literally eroding and it's corrosive. So the response to the body to heal that is inflammation. And we have to understand is that inflammation in the short run heals us, but chronic inflammation kills us. At the end of the day, we don't die of old age. We die of inflammation and acid reflux in its core root is an inflammatory issue. And that inflammation turns to ulceration, ulceration turns to sclerosis because that tissue begins to harden up. And as it hardens, why is it doing that?
22:08It's creating this, literally this armor, this self-defense so that it can actually withstand that acid that's become chronic. So anytime you see someone with those tissue changes, which by the way, happened to my father, he has so much sclerosis of his esophagus. They had to do a 10 hour robotic surgery where they removed two thirds of his esophagus, half of the stomach. They brought those tissues together. So now his stomach was living up here. It was crazy. So again, this is a very serious problem. I know a lot of guys, I'm one of them, you know, when we get acid reflux or any symptom for that matter, it's like, yeah, it's, you know, it'll go away or, you know, we don't have to take it serious until we have to take it serious, right?
22:47We are motivated by pain historically. And the more pain where it gets to the point where it's interfering with our lifestyle, that's when we tend to become serious with it. But if you have acid reflux, you got to get on top of this. It does not have to be a death sentence like it was my father. This is reversible. I do it every single day. But you got to get the foods out of the diet that are called weapons of mass destruction, the foods that are acidic and inflammatory, those ultra processed foods, Dr. Mills, that you were talking about. You know, you reminded me, I was thinking of that commercial from years ago when the proton pump inhibitors were coming out.
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23:19They're all generic now. So you're not going to really see commercials on it where, you know, the guy's at a barbecue and he's eating, you know, rib after rib. He's got barbecue sauce coming off his face and he obviously looks like the pin of the what exactly the the health that we don't want to exude and then the whole thing is like just you know take this pill and you'll be good you can go back same way the next day and uh and it's just that just i mean again like i you know we the pharmacy industry i'm not going to get into because we you know there's a lot of amazing things they do but but if you're selling yes somebody a pill instead of trying to convince them of a lifestyle and putting in the work, you're going to end up with this giant blanket or at least a cover-up of what really is done, which is putting in the work.
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28:02Man, I got you here. You know, bestselling author, multiple books, such a wealth of information. You've said twice about sugar addiction. And I'll preface this by saying, of course, that the addictive hormone is dopamine. If you're hungry and your body thinks it's starving to death, one of the things you have to do is turn up some kind of reward hormone, right? To say, I got to do something so that this pain goes away in my gut. And what's the fastest way to do that? Simple sugar. So talk to me through that. So what do I do instead of my sugar addiction? how do you focus an acid-friendly or reflux-friendly diet so that we can turn our lives around?
28:44That basically gets get off your acid and get off your sugar, your two books into a 90-second. Tell me what to do, then go buy the book, everybody. Yeah. I mean, sugar pumps up your dopamine eight times more than cocaine, which is actually one of the craziest stats I've ever heard. As I said earlier, it's a drug. It's become America's drug of choice. one thing I've learned is that, you know, sugar addiction, which so many of us have. And if you don't know if you have it or not, just try not to eat for five hours to see how you feel. The cravings come crashing in, right? So what we need to do, my whole approach now, it's not about deprivation, it's about moderation, but more importantly, not about giving up the foods you love more.
29:23So how can I make this food that I love that might be really bad for me? It's acidic, it's inflammatory. How can I make that a better version of that food? So it's really about adding and not taking away. Because a lot of people, when they're really dealing with a health crisis, yes, medicine is a godsend. I mean, save both my parents' lives, save my life. But PPIs are never meant to be taken for more than 14 days. I mean, you look on the box, it says 14 days. And the research shows that from a PPI standpoint, 54 % of the time, it doesn't even give them the symptomatic relief. So I'm all about someone doing something to walk them off the edge of the cliff, which is important.
29:57I wish my dad had that back in the day when this was found out. But it's all about looking at those foods that can actually strengthen our gut, strengthen our microbiome, lower inflammation, soothe and calm. So we have to avoid things that are very acidic. When I say acidic, citric acid foods, spicy foods, onions, garlic, chocolate has a substance called methylxanthine, which basically will soften or relax that lower esophageal sphincter, which we don't want. So instead of doing something like a cocoa, let's do more of like a raw cacao, which is high in minerals, low in sugar, and that will have a different effect on the body.
30:31Let's stay away for now for the alcohol and the coffees. No, don't say coffee. Hold on. Hold on. Hold on. Hold on a second. Here's what I'm going to say. It's not about giving up coffee. Oh, thank God. And I'm not here to pitch my price or anything like that, but we have an amazing, which I basically created this because Kelly Ripa back in 2015 went on her show and she's like, you know, this, you put me on this seven day detox and alkalized my body. I feel great, but I'm still drinking my coffee. Didn't tell him. So when she said that, I'm like, all right. It's not about trying to fit into this lifestyle.
31:03How can we fit this into your life and your lifestyle? So I created this powder, which I'm going to send to you, Doc, which you add to your coffee and it neutralizes all the acid in the coffee. Because the reality is there's a lot of upside to coffee. But the one huge downside is it's so acidic. It's 100 times more acidic than this water that I'm drinking. So for people with reflux, they love their coffee. A lot of them don't give it up even though they suffer through it. And we don't want to do that white knuckle approach with sugar or coffee. So you add this powder to it. And basically now you get the upside minus that downside.
31:33And I have so many patients and clients that have severe acid reflux. They're doing this and they're still drinking their favorite cup of coffee. So not about giving it up. Well, I was going to say, we have a segment that this goes right into for all of my guests called, am I going to be okay? And I think now's the deal is that, right, I have a huge coffee. I'm sorry, a huge coffee drinker, but I, you know, I have two cups in the morning. And then before I work out, I do that boost. And the thing about coffee, first of all, it sounds like you're going to tell me, you're probably going to, well, I'll let you, I'm not, I'll let you be my doctor for a second here, Dr.
32:04Darrell. But it does, you know, alcohol, coffee, again, it relaxes that lower esophageal sphincter. And so it's not only about the acid, but it's containing the acid in an organ that's meant to see acid, keeping it away from an organ that's naive to acid. But tell me, do I get two cups a day to be okay? Or tell me how I'm going to be okay and still be able to drink my coffee and prevent Alzheimer's and diabetes and depression and all the things that you were saying, alluding to that coffee has some pretty good data for? Yeah, I mean, listen, there are a lot of upsides to coffee. Let's not deny that.
32:34My major concern with that is that it's just so acidic. There's nothing wrong with having two cups of coffee. But my suggestion is everybody do your best when you can to try to drink organic coffee. me who has a history of mold toxicity where I literally almost died four or five years ago from it I have to be very careful about mycotoxins and mold so I also drink mold-free coffee as well it's safer because coffee beans are probably the most contaminated bean with pesticides herbicides fungicides but not to mention they become incredibly moldy and mold is very dangerous to the body so it's really again not about giving up that coffee but how can I neutralize that acid And you just do that one little packet in there, or we have a flavor version.
33:13And we have one for alcohol too. You put five drops in your alcohol because alcohol is even more acidic than coffee. I mean, last year, the surgeon general stated as the third cause of preventable death in this country behind obesity and obviously smoking. So something like beer is a fermented grain. Obviously, that's bad. There's gluten. There's other things that we have to avoid. So that's like the one that I never go to. So sorry, beer drinkers. the middle of the road is your wine, which is 10 ,000 times more acidic. But like the best alcohol, if you're going to go this route, guys, is going to be something like a gin, a grain-free vodka, or a tequila.
33:48It's just about, you know, never better best. So we know that people are going to make these choices, whether we like it or not, Doc. So how can we help them make better decisions with the choices they're making? You almost killed half our audience. And I think you just brought them back with tequila. So that That was a hell of a pivot. That was a hell of a pivot. There you go. Well, let's talk. You've danced around it. I was going to go into something different, but now you just said the G word. And so, yeah, walk me through. I mean, again, as a guy that went through medical school years ago, I remember one of my classmates came back after a little bit of an absence, and he was about 40 pounds lighter, and he said he was diagnosed with celiac.
34:28And I even at that point, it was probably my second or third year medical school, and I had to go back to my gut physiology to even understand what celiac disease was. And now fast forward, you know, it seems as if at least whether it's gluten sensitive enteropathy or whether it's gluten aversion or just walk me through what is going on with gluten. I mean, I don't even know where to start. So I need somebody to organize my journey. And how do I counsel guys on difference between true celiac allergy or gluten allergy, celiac disease, and just, you know, gluten free lifestyle? Right. I love this topic.
35:04And the first thing I always say is there's nothing free about gluten-free. I want to explain what that is. Is it okay if I spend 30 seconds just getting two or three quick hacks to help people with reflux to soothing calm? Because I don't want to leave them hanging with that. So real quick, guys, Slippery Elm tea is phenomenal because it soothes and comforts and lowers inflammation from the mouth down the throat all the way down the esophagus into the stomach. I have no ties to these companies, but Yogi makes something called Throat Coat tea. traditional medicinals makes throw coat tea because you know it's just an easy way to get a packet throw it in a cup of hot water and boom drop to the races i love that you can get some local honey and just take a teaspoon two or three times a day local honey is very powerful um it's got strong healing effects even though there's a little bit of natural sugars in there but what i also like to get is some propolis or propolis however we call it and i put three drops of propolis in that honey which you can get from a local honey producer propolis has incredible um healing effects to the esophagus and the stomach lining.
36:03Research shown they can actually heal ulcers. Very powerful anti-inflammatory. So I love that as well. You just reminded me of something I haven't thought about for a while. When I did a surgical residency, but I did a full year of research in the lab up at University of Colorado Boulder with a guy named Norm Pace, who's a National Academy member. He was a guy that actually discovered bacteria in rock, you know, millions of years old. And one time we had a lunch in the lab when he got done with lunch and he was brushing honey on his teeth. And I said, you know, Norm, Dr. Pace, what are you doing?
36:34And he said, you know, honey is a natural antibiotic. There is no bacteria that synthesizes the sugars in honey. And it actually said, this is what I do instead of brushing my teeth is honey. But I think what you're saying too, is if you think about some of the other things we didn't really talk about, one of the big, big issues with ulcers, of course, is the H. pylori and the bacteria. to wonder if some of the other aspects of honey are just the natural antimicrobial properties of it too. So that triggered me, but I love this. All right, I didn't mean - Yeah, no, I love that. I love that. I love how we're going down these little holes because H.
37:06pylori, it's a commensal form of bacteria that 95 % of us have, but when it becomes elevated, it becomes very damaging. And H. pylori lives in the stomach. Why or when, when there's low acid? Because acid kills bacteria, like you said with E. coli before. So if you see H. pylori in there, and I see this all the time with our GI map testing. It's a really powerful stool test that we do. It means and confirms that there's low acid in the stomach. And this little bugger is so smart, it'll literally burrow into the lining of the stomach. It'll secrete its own enzymes to block your stomach's own production of hydrochloric acid.
37:40So this thing will actually increase the biologic terrain that's conducive to its own longevity. Yeah. So one of the best things we can do is, if you could withstand it, a little bit of apple cider vinegar in some diluted, in some water, Warm water about 20 to 30 minutes before your biggest meal of the day. It'll gently increase the acid in the stomach. It'll also kill off the H. pylori. And there's other things to go about it. But this is what we're saying is that there's so many different underlying things that happen when someone has reflux, which is why you can do things like slippery elm or the local honey or a peptide like BPC-157.
38:14You can open that in a little water and drink that because that heals ulcers. But ultimately, we've got to get to the root cause. We have to test our gut. test not guess is my mantra because when you look at the entire microbiome then you can actually figure out the entire picture what's off what's out of balance what's driving up inflammation what's causing leaky gut and then when you address that root cause it's incredible how the body knows how to heal itself because we are self-healing we are self-regulating but we have to just kind of help that body get to that state yeah gluten is a big part of this one because so many of us are eating it on a daily basis yeah no i i would say as as a surgeon i always tell my patients It's, you know, this, I have an easier job than a BMW mechanic because mechanics have to get everything exactly perfect because there's no self-healing in your engine.
38:58But, you know, if your incision has a little work to do, it's amazing what it can do to heal itself if you give it the right tools and set it off with a good operation to begin with. Right. So, no, I love it, man. We're talking the same language. Tell me, tell me about gluten. Yeah. I want to hear your spin on this. So gluten's a toxin. I mean, yes, 1%, which the research shows of the population will get this celiac disease, which is really an autoimmune disease based on high sensitivity to gluten. I think that number is actually higher. So I would love to talk on what's really happening with autoimmune disease because it's really tied into the gut.
39:30But the reality is that we should really all be trying to avoid gluten because even if you don't have celiac, gluten is what I call a weapon of mass destruction for the gut. You know, it increases the zonulin, which is a protein in the gut that will basically, Zonulin controls the opening and closure of the tight junctions of the gut. So when there's gluten, it's basically like creating little Swiss cheese holes in the gut. We can make that simple. It doesn't quite work like that, but you know, you, you gotta look at your gut and in between your gut and the body, the blood is this barrier. It's like a dam.
40:01And that dam, when we eat our food should basically break down, absorb, take in nutrients and kick out all the bad stuff out. When we have leaky gut, which I'm going to tell you a hundred percent of the population has, albeit different degrees. The research says that number is much lower, but I also do something called live blood cell analysis, where I can actually see in the live blood sample, different sorts of things creeping in or leaking in from that gut into the blood. So it's something that we all have to deal with. And why is that? It's because the gut is our first line of defense. The gut has become a literal minefield.
40:33I mean, we are all subjected to so much toxicity from the foods that we eat, the water that we drink, the air that we breathe. And the gut is really what's that first line of defense that's stopping all that bad stuff from entering into the body. So gluten, it's kind of interesting when we say gluten, it's like glue. It's like glue to the gut. That's what binds these foods like pasta and breads. But the reality is that if you really want to heal your gut, if you want to lower inflammation and decrease the level of leaky gut, we have to get it out of the diet. Now, listen, if you have it here or there, we're not going to beat you up, right?
41:05Some people can actually tolerate it more than others. If my gut's stronger, I can typically tolerate something that comes into the gut that's going to cause damage, whether that's gluten, sugar, a seed oil, an artificial sweetener, or something stronger like a stealth pathogen like an E. coli or a pseudomonas or a klebsiella or a parasite or an active virus. So again, that gut wall is critical basically because when we have a strong gut wall, things get contained in the gut. They get eliminated out of the body through our stool. But when we have leaky gut, now things that should never get through that gut wall, which is what gluten causes, now enter into the body.
41:43And once they enter the body, things like inflammation, yeast, fungus, mold, bacteria, different forms of toxins, now it becomes a systemic highway to the rest of the body. Now it's where's the least or the weakest link in the chain. It could be the reproductive system for some people, the thyroid gland, one of the first glands that gets hit by leaky gut, the liver, and of course the brain. When we see people suffering with anxiety, depression, ADD, ADHD, there is an intimate connection to the gut because there is something called this gut-brain connection, all connected through the vagus nerve.
42:16So again, gluten is one of those foods that ideally none of us should be doing. And the problem is, is that when you go into the aisles of these supermarkets and it says gluten free, well, the good news is they took the gluten out. But the problem is, is that now that food tastes like cardboard. So in comes to the rescue. They bring in the sugar, the artificial sweetener. So they're basically just swapping one really horrific ingredient for another. So don't be misled by that. And the other thing, when I said before, there's nothing free about gluten free. To be gluten free, it has to be free of this protein called gliadin, which is found in wheat, barley, and rye.
42:51But I could take something like a gluten-free oatmeal, which does not have gliadin. It has another protein just as damaging as the gliadin found in gluten. It's called avenin. And that avenin is going to cause the same destruction in the gut that gluten will. So even though it says gluten-free, there's over 400 different proteins in the gut that can actually do this from foods. Right. I'm glad you touched on that because I think that is critical is that gluten is just one of multiple things that can trigger people that. In fact, there is gluten-free wheat that's imported from Italy that can still trigger people with gluten sensitivities because it's not truly a gluten sensitivity.
43:29But boy, this is coming from an Italian from New York. So what, like, man, I can't even imagine the cultural betrayal that you are dealing with to say this. And so, okay. And I also love the fact, one of the things that drives me crazy in nutrition is when you try to do these uncanny recreations of something that shouldn't exist in nature. And I go back to like the snack well craze of, you know, when you're probably a couple of years younger than me, but sort of when everybody's like, we got to get rid of all the fat. There's no fat. So these are no fat cookies that have seven times the sugar in them, but there's no fat, right?
44:09So you're thinking, oh, this is so healthy for me. because I'm not eating. And now you're saying the same thing. People look at gluten and gluten-free products as healthy because they're like, gluten-free, gluten is killing me, but they're replacing with things that are going to kill them just as fast anyway. So yeah, it's such a fascinating topic where the sugar industry basically came in the rescue because they demonized and villainized fat as the cause of why people were having more cancer and cholesterol and heart disease and things like that. But if you look back, I think there was actually three Harvard scientists that were paid over$50 ,000, which at the time was a lot of money to actually manipulate the study showing that the fat was the cause.
44:46And we have to understand that there are fats that heal our bodies and fats that kill our bodies. So the fats that we don't want to put into the body are those seed oils, literally more damaging, more destructive than sugar, because sugar will get burned off by the body because the body recognizes this as a fuel needs to burn to get rid of. But the problem is that the seed oils can't be burned off. They have a half-life of at least seven years. So they literally rust and rot you from the inside out. They go to the brain because the brain is 60 % fat, has an affinity. So now you're competing. These omega-3 fats, which are like salmon and fish oil, which are anti-inflammatory versus these seed oils, like canola oil and sunflower and safflower and peanut oil and all these other bad oils, the list goes on and on.
45:28Those are the ones that drive up inflammation in the body. And if you look at Dr. Atkins back in the late 60s and 70s, I mean, his research was incredible. so ahead of his time, but he was talking about sugar and carbs. The interesting thing is if you look at historically the last 50 years, sugar has actually been less consumed. I'm talking about the white sugar, but what's gone massively increased in our diet is the seed oil. So I think when you remove all those bad foods from the diet, the baked goods and the chips and all that stuff, yeah, you lower the sugar intake, but you also lower these damaging seed oils, which are so destructive to the human microbiome and the brain.
46:02Yeah, you're right. And I think that my problem is that, you know, the seed oil data, I think the issue is, is that it is an ultra processed food in the sense that you would have to eat an acre of seeds of sunflower seeds of anything in order to, to get the amount of oil that comes into one tablespoon. Right. And so what you're trying, what you're doing is it's all, and I think you do such a good job of talking about this in, in, in your books and in your talks about everything in moderation. And there are some things probably shouldn't at all, but, but certainly when you dose response, something, you overwhelm the system with something that never occurs in nature, that's where we get in trouble.
46:38And I think that's certainly what we're seeing is that, you know, I always go back to, you know, if you eat an apple, you're right, you've got the skin, you've got everything, you've got the juice. If you had five apples, nobody could sit down and eat five apples at the same time, right? But you can easily drink. I hate that. You're like, there are five apples in this apple juice. I'm like, well, that's terrible. That's not a good thing. That's a terrible thing. And it's the same thing with any of these ultra processed foods, seed oils. All of it is that you're taking something that in very small doses is probably nowhere near as toxic as if you're putting it into something that you rip out of plastic.
47:15And it's so easy. It's so cheap. You know, these oils are so cheap to manufacture levels that you're replacing things. Salmon is not cheap. And so the good the good omega three is, you know, there's no cheap source of those. And so it's hard to figure out how to formulate a diet that's accessible to everybody. But I mean, again, everything you said, it really makes sense in terms of this is ultimately excess, lack of moderation, and lifestyle driven. So yeah, man. And touching bases on celiac, you know, real quick, you know, there is a genetic predisposition with people that have celiac, and there's nothing we can do about that.
47:54It's like your gene is your gene. Epigenetics means that we can actually change gene expression by how we eat, how we think, and how we move. And two other things that we can actually change with someone that has celiac or any autoimmune disease, I don't care if that's Hashimoto's in the thyroid, MS in the brain, rheumatoid arthritis in the joints, there's two things that we have to address. Number one is a dysbiosis or out-of-balance gut, leaky gut, where you have more of the, look at your gut like a garden. You want lots of flowers, your good healthy bacteria like your probiotics. you don't want the weeds.
48:26And for most of us, the weeds are overtaking the garden and they eat their way through that gut wall, causing that leaky gut. So there has to be that in place. And number two, an environmental trigger. And the list is very small. I'm talking about a food toxin like gluten or dairy. It could be a pesticide, an herbicide, a fungicide, or glyphosate, or it could be a stealth gut infection like an inflammatory bacteria. We talked about those before, parasite and active virus. So basically when you have those two things in place, you have dysbiosis and leaky gut. And now this environmental trigger that is going to cause a hyperimmune response.
49:03Those things will actually leak through. They'll attack a specific organ, whether it's the gut or the thyroid. So now your immune system comes into the rescue with its first line of defense. It's like a blowtorch, right? It's the innate immune response. It starts to blow up all these bad guys. But the problem is that while it's blowing up the bad guys, there will be friendly fire. There will be collateral damage. Your healthy cells will get blown up. Your proteins will get blown up. So now the more smart part of your immune system comes in the adaptive part, your B cells and T cells. And you get these like little Pac-Man style cells called macrophages that eat up all the bad stuff that have been killed.
49:36And they say, here you go, B cells and T cells. We're going to give these to you so you can actually make an antibody to this bad guy that we just killed. So if ever we see this guy again, we're going to know the second entrance of the body high alert, we can kill it. But the problem with autoimmune disease is that there becomes an accidental presentation of these healthy cells that got killed off in friendly fire to those same B cells and T cells. So now your immune system is making antibodies to your own body's tissue. So it's not the immune system going haywire and one day just saying, you know what, I'm going to rebel on this body.
50:12I'm going to just decide to go after the thyroid gland or go after the gut. It doesn't work that way. It's going after something that's foreign, something that's bad that shouldn't belong there. It's getting rid of that, which is what it should do. It's creating this hyperimmune response. So ultimately, if we start to get that gut back in balance, increase our probiotics, get foods in like leafy greens and omega-3s and more fiber and bone broth and things like that, that can heal the gut and eradicate some of these bad guys, then these are not going to infiltrate the body. We're not going to have the hyperimmune response and autoimmune disease is reversible through these ways.
50:45It's a lot more extensive than that, of how we go about it. But my whole point is that we can help the immune system fight the real fight by getting to the root cause. Yeah. And I think you touched on, you know, we sometimes call it the two hit hypothesis that you have this predisposition, genetic, whatever we want to say that has an innate predisposition to something. And then, you know, it's an environmental trigger that sets us off. And so, right. I mean, I think the nice thing you did there is you gave us a little bit of a roadmap on how to start healing ourselves and how to, how to partner, you know, with a good healthcare provider to, to get us to that level, which is really, you know, what we're all about with all the passion and enthusiasm you bring.
51:25I'm, I'm super pumped to, to heal my own gut and to get out and maybe still drink my coffee, but now you need to have like the powder that you can put over a pizza so that you can, you might be responsible for the next big, Oh boy, here it comes. All right. No, you got it. It's all about kicking your coffee's acid. That's what you got to do and then enjoy it. Right. Listen, we got to enjoy our life. That's one thing. You know, I've always been an extremist where, you know, when I was a sugar addict, I would kind of go one way off the rails and try to heal my body. And then I would go all the way off the rails the other way.
51:56It just doesn't work. We got to find a rhythm. We got to find a flow. As I said, you don't have to give up everything, but just start adding, even though it's one thing at a time, it could be a green smoothie. It could be a green juice. It could be a salad. It could be a probiotic or magnesium supplement. Pick one thing, master that, do it for seven days and go to the next. Yeah, it might take us a little longer to get to where we want to go, right? And there really is no there. It's all about optimization, but we're going to get there. It's about progress, not perfection. As long as we can put in steps every single day to get us closer to our goals and know what your goals are, we're going to improve the health of our body.
52:29Love it.
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56:29all right so i always have this on my segment too what is the one must have for dr darrell what do you have to do every day what do you get up and say i have to do this to to center myself to ground myself to bring the fury and passion that you bring to your practice what is your i can't i I have to do it. I just got chills when you say that because this is my kind of morning routine. I wake up and I pray. You know, I'm very grateful for being alive. I'm grateful for my family. I'm grateful for the people I get to help and serve. I'm grateful for living in this amazing country of ours. I just have so much gratitude in my life.
57:05And I noticed that there are periods of fear in my life when I think about my father and I think about some other things that have happened, traumas in my life. Fear is just false evidence appearing real. When I start to have gratitude, gratitude will crush fear in any sense. So I start with a prayer and then I do some meditation. It doesn't matter if it's five minutes or an hour. There's some days my meditations are awful. There's some days they're great. But just having that time to abide in silence and just breathe and really get my parasympathetic nerve system in check and kind of create that flow, it's important.
57:36And then the third thing is I just want to always move my body. Yeah. I've had some pretty serious injuries where I broke my neck and low back things. So even if it's going out for a brisk walk or going on a field and taking off your shoes and doing some walking in grass and doing some grounding. You know, you live by the ocean there in California, nothing more charging than putting your feet in some salt water. So for me, grounding and just moving my body is critical. And then I always want to nourish my body with something very healthy in the morning. So I always start with a green juice, whether I'm making fresh green juice in my juicer or a green smoothie or taking a scoop of my acid kicking greens, throwing that in the water and just mixing that and drinking that.
58:12So I really just try to infuse positivity, strength, and life into my body. I don't watch the news. I don't read the papers. I just don't because I don't want that negativity stuff because it's all about sensationalism if it's going to be on the news. So I don't want it there. I'm aware of what's going on in our country, in our world, but I want to take care of myself and put the right things into my mind, the right things into my body, physically, emotionally, chemically, and spiritually. Wow. That's a win. Chills right back. I mean, you hit me there with the message of gratitude and all we have to be thankful for.
58:46And yeah, there's really nothing going on in the news anyway, man. So you're not missing anything at all. You can trust me and I'll let you know if something big happens. Other than that, dude, just keep whistling. Keep doing what you're doing. You've managed to keep my producer speechless for 50 minutes as well. So Jordan, what's up over there, my man? What are we missing? I mean, the guy, obviously, like, again, I mean, the passion, I can't tell you how just pumped I am after spending this time with you, Daryl. This has been so cool. But Jordan, what are we missing from the common guy? Yeah.
59:18What are we doing? Like, Jordan is our voice of the guy that's out there living his life in his mid-30s. And I saw him taking notes. So I already know the things that he's going to do different action items wise. But speak to us, brother. Well, I love your passion as well. I am equally as passionate, unfortunately, about sugar, that I have the dietary habits of an elf. Yeah. We got to bring Dr. Darrell back. And you're going to tell him you have homework, Jordan. We're going to bring him back in a few months. And we're going to say, dude, what are you doing differently? But all right, hit us. Oh, that's what I wanted to ask you.
59:51I cannot tell you the number of times I've tried to do, you know, what I'll refer to as sugar detoxes. And, man, I've detoxed off a coffee. I've detoxed off a lot of things. It is never has there any been anything that has felt that hard. Yeah. What are just like really going through those first couple of days? What's some advice you could give? Jordan, here's what happens. So we get to January 1st. Most of us are sick and tired, right? And not feeling well. And then we set these resolutions. Let's resolve today to make a change. Make one change, not, not a hundred percent off sugar, but then the research shows by January 17th, 92 % of people fail with the resolutions.
1:00:29one of those top three being getting off sugar. It just doesn't work because what most people do, and this is, you might not like the answer, but this is the answer I'm gonna give you, and I'll give you some other little hacks. Most people associate changing their health in their body with the flip of a calendar. The problem is it doesn't work. They just changed and said, I'm gonna do this, and it's all based on pain. Oh, I gotta go to the gym. I gotta give up sugar. I gotta do this. And it's funny because what do people do? They start counting down the days, whether it's sugar, smoking, or whatever the vice is.
1:01:00I've been off sugar 16 days. I've been on sugar 21 days. They just count so that they can tell people, I made it 33 days until I got back on the wagon, right? I could have written that book, Get Off Your Sugar in One Page, which is, yes, the map, the massive action plan, the strategy, the biohacking, the little things you do. Like if you have a craving, you can take some cold ice water, put your face in the cold ice water. Literally, it's like a cold punch, shocks your nerve system, increases your endorphins, your encephalins, and basically reset your nerve system. So that'll help as something that you can do.
1:01:30Getting your body into parasympathetic state by vagus tone. I mean, you can just hum, you can gargle water in the shower, but that book could have been written in one page by saying it's all about your why, your purpose. If you have the why, you comply. Because I can tell you for me, I've tried every single detox. I've made every single sugar detox. They're great, but a lot of them are very, very tough because we're not really getting to the root cause, which is this up here. It's the big thing between the two years, which is our psychology. And if your why is big enough, your why, your purpose, your reason, why you're doing something, your how will find a way.
1:02:06So what I think you need to do is spend some alone time, five minutes, 10 minutes, 20 minutes, and just start to write out, like, what is your purpose in life? And I mean, it's like, get deep with yourself. Like, it could be a superficial why, like, I want to lose some weight, I want to have more energy. But like, what is something deeper than that? Like, what's something that's so compelling? When you think about that thought, it moves you down to your very soul. It gives you goosebumps. For me, when I couldn't get off my sugar for, you know, two months off the wagon back on it, 12 months back on it, two days back on it.
1:02:37I mean, literally, I was the yo-yo for many, many years. And finally, I just had to kind of dig deeper and say, you know, this is about my dad. This is about my children. This is about wanting to be around my kids so that when they're older, I want to be a healthy dad. Like I really got deep. It was about me to some extent, but it was more about the people that I love. So I don't know what that is for you, but I can promise you this. When you have a big enough why and you're going through your day, you get a sugar paving. You have that written down right there. You have a picture of something that matters to you.
1:03:05It could be your mom, whatever it is. I don't know, but I'm committed to this right here. I'm going to do whatever it takes to honor this person or whatever that is that you're committing to with that. Why I promise you, you are not going to shake. You will not shake. And that ultimately was how I got off of sugar. Now also remember that sugar changes your taste buds every 14 days. So they become desensitized. So your taste buds will be new taste buds in 14 days. So if you start to do things that will cleanse and detoxify, you could do like a, uh, an olive oil, you get one tablespoon of olive oil, half the juice of a lemon, mix that together, drink that.
1:03:38That's an amazing thing you can do. You can get apple cider vinegar, throw in a little sea salt, a little cinnamon, drink that. I mean, it's a bunch of different hacks that are my get off your sugar book that you can access. Probably my biggest thing is that when the craving monster comes, just sit with it for a second and don't go for the snack, right? The very first thing that you want to do is you want to move your body because motion is emotion. So get up out of your chair, do some jumping jacks, walk around, do a little yoga, do a brisk walk, do it for five minutes. Again, it's stimulating your endorphins, your encephalons and all those good feelings of hormones.
1:04:10And then wait a few minutes to see how you feel. Many times that's enough. Number two, I'll drink a big glass of water. But water's neutral. I want to kick its acid. So I'll get a lemon slice, a lime slice, scoop of my greens. I'll put that in there. I'll drink that because that's going to alkalize me, which neutralizes the effects and the cravings that sugar has. So I'll do that, wait a few minutes, and I'll see how I feel. If I still have that craving, then I'm not going to go to a Snickers bar or something really toxic or acidic for my body. I'm going to go for a healthy snack. I'll get a green apple.
1:04:39I'll slice them up. I'll get some cinnamon on there, which helps insulin instability and helps manage blood sugar. I'll get a little raw almond butter and I'll dip them in the almond butter and I'll eat that. It's satisfying. It's crunchy. It's going to fulfill your sweet craving, not maybe like a Snickers bar. But my point is this would be a good swap for something that we were maybe doing that wasn't serving our higher purpose. Heck, yeah. Pick up your guitar, man. Do a little slow jam word, brother. A thousand percent. Yeah. Smile. Like something that stimulates you and makes you happy because it's all about peak state.
1:05:09Anything that can change your state is going to help you. So I love guitar. I play the ukulele, by the way. Probably not as good as you are, but I just will go in there. I'll jam some reggae tunes or some Hawaiian tunes, and that's kind of what gets me out of my stressful state. And anything that's going on, whether it's sugar or anything bad, I just start to strum that guitar, man. It just brings me to that PTC, present time consciousness. I love it. Yeah, boy, and we marked the passing of Jimmy Cliff recently, one of the legends of reggae music. Legend. Wow, so yeah, now you're going to make me pull up some Jimmy Cliff.
1:05:38Love it. Well, you know, Dr. Darrell, Jordan, we really should not be allowed to have this much fun or have this much information in this time. But that's the beauty of what we're doing. Dr. Darrell, I'm so grateful for your time, your expertise coming on and really breaking it down into what guys can do for themselves, as well as what you can do for them through all of your outreach work. It's just been it's been a joy. And I look forward to working more with you over over the years to come. Thank you so much for your expertise. Thank you so much, guys. Appreciate you so much. Thanks for having me on.
1:06:11Heck yeah. It's been an awesome time with you guys. And I love to see you guys having so much fun telling the story, helping people get better. You're just you're amazing. Thank you for having me. It's all about the story. All right, my brother, be good. Keep doing good out there. Be good, guys. All right. Thank you so much. All right, y 'all. We'll see you next time.
1:06:37Let's talk about it.
1:07:01The Mailroom with Dr. Jesse Mills was a production of iHeartRadio. It was executive produced by Jordan Runtog. It was edited, mixed, and mastered by Bahid Frazier. And the theme was provided by Long Transit. If you liked what you heard, please subscribe and leave a review. For more podcasts from iHeartRadio, check out the iHeartRadio app, Apple Podcasts, or wherever you listen to your favorite shows. This program is intended for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Consult your health care provider for any medical or other related questions or concerns.
1:07:40The views and discussions aired on this podcast are those of Dr. Mills and do not represent the official positions of UCLA or UCLA Health.
1:07:56When people turn to healthcare for weight loss, they're looking for real support. That's why more people are choosing orderlymeds.com. Orderly Meds connects you with real doctors and access to proven GLP-1 medications like semaglutide and terzepatide. No guessing, just a more supportive experience. And all shipped directly to your door in discreet packaging. Do your research. Ask questions. Then visit orderlymeds.com slash podcast for an exclusive offer. That's orderlymeds.com slash podcast. Individual results may vary. Not medical advice. Eligibility required. See site for details. When you manage procurement for multiple facilities, every order matters.
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From the publisher
Dr. Mills is joined by celebrity nutritionist and gut-health expert Dr. Daryl Gioffre to break down what’s really driving America’s acid reflux epidemic—and why the root cause is often too little stomach acid, not too much. After revealing the deeply personal story that pushed him into this work following his father’s battle with esophageal cancer, Dr. Gioffre shares practical strategies to support digestion and protect the esophagus — from the “three-hour rule” before bed to simple soothing tools like teas, honey, and magnesium. The conversation also gets into why sugar is so hard to quit, how ultra-processed foods (and “gluten-free” swaps) can backfire, and how to make realistic upgrades without white-knuckling your way through life—including how you might keep your coffee and calm your gut.
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