In short
Colon cancer trends and prevention, focusing on environmental exposures (microplastics/nanoplastics, glyphosate, hidden food chemicals), diet (ultra-processed foods), and the gut microbiome’s role in low-grade inflammation and hormone metabolism. Also covers stress–gut–microbiome links and emerging microbiome-based approaches to perimenopause/menopause (estrogen recycling) and testosterone regulation.
Guest background
Dr. Imran (Emeran) Mayer is a gastroenterologist and neuroscientist with 40+ years of research on the gut-brain connection and chronic disease prevention. He has authored 400+ peer-reviewed studies and books including The Mind-Gut Connection and The Gut-Immune Connection.
Key claims
- Screening has reduced adult colon cancer, but cases are rising in younger adults (down into the 30s).
- Likely drivers include diet and environmental exposures; microplastics’ effects are not fully known (“black holes” in science) but exposure appears increasing.
- Ultra-processed foods are associated with higher risk of early-onset colorectal cancer.
- Stress can influence gut inflammation via microbiome/immune pathways.
- Gut microbes can recycle estrogen/testosterone via beta-glucuronidase; this may explain variability in menopausal symptoms.
Notable examples
- JAMA Oncology study: ~30,000 female nurses <50; highest ultra-processed food intake linked to ~45% higher odds of early-onset colorectal cancer.
- Celebrities mentioned as recent losses: Catherine O’Hara (Home Alone; The Studio) and James Van Der Beek (Dawson’s Creek).
Written by AI. May contain mistakes. Listen to the episode to check what was said.
Chapters
Tap a time to open that second in VOThe Rise of Colon Cancer Awareness
0:45 to 3:00
Discussion on the increasing awareness of colon cancer after recent celebrity losses.
“and recently we also lost James Vanderbeek, who was somebody who came to stardom through Dawson's Creek which was a part of many of our upbringing.”
Communication and Sharing Health Challenges
3:00 to 7:30
Emphasizing the importance of sharing health struggles and not suffering in silence.
“And he's going to share the latest science regarding this for prevention and also the best practices for finding out the early warning signs.”
Interview with Dr. Emeran Mayer
7:30 to 11:15
Introduction and insights from Dr. Emeran Mayer about gut health and cancer.
“detect if there's any blood in it, occult blood in it.”
Understanding Colon Cancer and Its Risks
11:15 to 14:03
Dr. Mayer discusses the increase in colon cancer among younger demographics and contributing factors.
“But there's not really what I think would be the most important thing, the patient education.”
Understanding Colon Cancer Screening
14:03 to 18:02
Learn about the potential benefits of earlier and less invasive colon cancer screenings.
“You could say a lot of money could be saved for the healthcare system if the initial screening should annual the cheaper tests starting at the age of 30, really.”
The Impact of Diet on Colon Cancer
18:02 to 24:16
Explore how ultra-processed foods are linked to increased risk of colorectal cancer.
“And most importantly, how do we reduce the risk?”
Microplastics and Colorectal Cancer
24:16 to 26:28
Discover the connection between microplastics and rising cases of colorectal cancer.
“We have a genetic component, we have an environmental component, and there can be things stacked against you that you don't even realize.”
The Need for Early Screening
30:54 to 31:39
Discussing the importance of early screening methods for colon cancer.
“You know, again, we're with this emerging conversation.”
Holistic View of Health and Disease
31:40 to 36:34
Understanding the complex interplay of genetics, diet, and lifestyle on health.
“And so for us to change that, it's going to take a lot of collective voices, but it starts with you as an individual and what you're doing with your family.”
Mind-Gut Connection and Colon Cancer Risk
36:35 to 42:00
Exploring the relationship between stress, gut health, and colon cancer.
“um and generalize it everybody will get benefit from it that's not the case you know So you may be somebody where that plays a big role, but in somebody else, it has not the same effect.”
Show all 23 chapters
The Impact of Stress on Gut Health
42:00 to 43:11
Explore how stress affects inflammation and gut microbiome health.
“definitely plays a role in this, you know?”
Understanding Estrobilome and Hormone Recycling
43:11 to 44:38
Learn about the role of estrobilome in hormone recycling and gut function.
“You have to have twice the sample size, more expensive to do males and females.”
Microbial Engineering for Hormone Management
44:38 to 47:26
Discover the potential of bioengineered probiotics for hormone management.
“And then these molecules, once you remove that sugar component, becomes water soluble and can be reabsorbed in the end of the small intestine and in the colon back into the circulation.”
The Future of Dietary Fiber and Microbiome Health
47:26 to 49:44
How advanced fibers could revolutionize gut health and microbiome diversity.
“So what I said about this enzyme, this beta-glucuronidase, there's hundreds of different subforms of it.”
Innovative Probiotics and Inflammatory Bowel Disease
49:44 to 54:28
Insights into next-gen probiotics that target inflammation in the gut.
“So they take natural fibers and slightly modify them and make them water-soluble.”
Skepticism and Insights on Probiotics
57:26 to 1:00:10
Discussion on the limitations of probiotics and the importance of prebiotics.
“You told me years ago about your skepticism about the probiotics out there, supplemental on the market.”
Understanding Microbiome's Role in Hormonal Health
1:00:11 to 1:02:00
Exploration of how the microbiome affects estrogen and testosterone levels.
“Well, again, thank you because you're changing this and, you know, conversations like this reach a lot of people and a lot of practitioners as well, just to start to investigate this more.”
Dietary Principles to Reduce Chronic Illness Risk
1:02:01 to 1:10:00
Key dietary recommendations to prevent colon cancer and other chronic illnesses.
“And having you here, what would be three dietary targets or dietary principles for us to follow to help to reduce our risk of developing chronic illness like that?”
The Impact of Chemicals on Health
1:10:08 to 1:11:28
Learn about the effects of pesticides and food chemicals on our health.
“And so making it a mandate, as you mentioned, one other thing you want to throw in here that you talked about briefly is the exposure to chemicals in our food as well.”
Connecting with Dr. Mayer
1:11:29 to 1:13:12
Discover how to follow Dr. Mayer's work and his new nutritional projects.
“where is a good place for people to connect with you, to follow you, to just get into your universe?”
Exploring Polyphenols and Olive Oil
1:13:13 to 1:14:48
Understand the health benefits of polyphenols and the unique olive oil product.
“I find that so attractive because, so it's unusual for a tree to survive 800 years.”
Book Projects and Holistic Health
1:14:49 to 1:16:33
Learn about Dr. Mayer's upcoming book and his vision for holistic health education.
“This is not a mega product, you know, it's...”
Dr. Mayer's Mission and Impact
1:16:34 to 1:17:46
Hear about Dr. Mayer's mission to educate the public on health issues.
“things the topics we talked about today because this holistic view of the world and our health and diseases affects everything, you know.”
Transcript
Automatic transcript. May contain errors.0:00Shawn Stevenson:You are now listening to The Model Health Show with Shawn Stevenson. For more, visit themodelhealthshow.com. Welcome to The Model Health Show. This is fitness and nutrition expert Shawn Stevenson, and I'm so grateful for you tuning in with me today. This episode is filled with incredible and timely insights. As of this recording, there is a surging conversation around colon cancer with the loss of a couple of very notable people in our culture. Catherine O 'Hara recently passed away with a complication related to colon cancer. She was well noted to be the mom from Home Alone. More recently, she was a big part of the Emmy Award winning show, The Studio.
0:49Shawn Stevenson:and recently we also lost James Vanderbeek, who was somebody who came to stardom through Dawson's Creek which was a part of many of our upbringing. And I actually have a close proximity relationship with one of these individuals and I had no idea about the situation that they were going through. And many people are suffering in silence with their conditions. And this is another advocation for us to communicate, to share with family and friends and not bear that burden of chronic illness on our own. And this could be, you know, absolutely a cancer condition or this could be related to depression.
1:32Shawn Stevenson:This could be related to struggles with our blood sugar and diabetes, whatever the case might be. Let's normalize not struggling on our own to figure things out. Even people just struggling with an injury or back pain, just being able to communicate to know that you are not alone and people care about you. And with this emerging conversation, I reached out to someone who's been in this field as a gastroenterologist for decades. I'm talking about when I was in diapers, he was treating patients and making a huge impact. And over the years, he became more and more invested in prevention. And so I asked him, is this new emergence of this conversation just a call out to everybody to run out and get a colonoscopy?
2:26Shawn Stevenson:Is that what the message should be? And you're going to be surprised at his answer. And most importantly, he brings up something that is wildly overlooked right now. as the age of a colonoscopy has been reduced even further, it's still well established that individuals who are much, much younger, we're seeing an incredibly high and rapid increase in the prevalence of colon cancer in younger and younger people. What is going on? So I'm going to be able to ask him about this as well. And he's going to share the latest science regarding this for prevention and also the best practices for finding out the early warning signs.
3:11Shawn Stevenson:Plus, in addition to this very powerful part of the conversation, we're going to shift gears and talk about some incredible new science regarding the gut, the microbiome, and testosterone and estrogen. Another thank goodness emerging conversation is happening right now around perimenopause and menopause. And there's a huge microbiome connection that you need to know about. And this is important for both men and women. We're talking about hormones that influence all of us. And it's so much bigger than a tunnel vision focused simply on reproductive organs. And so, again, this is absolutely filled to the brim with incredible insights and information that everybody needs to know.
4:00Shawn Stevenson:So without further ado, let's dive right in. Renowned gastroenterologist and neuroscientist Dr. Emron Mayer is one of the world's foremost experts on the gut-brain connection and chronic disease prevention. Over the past 40 years, his research and published work has offered groundbreaking evidence of the critical role of biodirectional interactions between the brain and the gut, and more recently on the role of the gut microbiome in these interactions, with broad implications not only for gastrointestinal diseases, but for metabolic and emotional and cognitive health as well. He's the author of over 400 peer-reviewed studies and the author of multiple best-selling books, including The Mind-Gut Connection and The Gut-Immune Connection.
4:48Shawn Stevenson:Let's dive in this conversation with the one and only Dr. Imran Mayer. Thank goodness we have a legend to be able to talk to. With the emergence right now, there's a resurgence in the conversation around colorectal cancer. And recently, a couple of well-known celebrities and influential people have passed away from ramifications of this condition. One of them being Catherine O 'Hara, the mom from Home Alone, America's mom in many ways, and James Van Der Beek, to name a couple of these individuals. And I have close proximity to one of them. And with this conversation emerging, it's such a blessing to be able to talk to somebody who this has been your space for decades and we were just talking before the show the conversation now with the microbiome and gut health and any related cancer this is something that you've been studying you know for literally for decades and now it's like in vogue and popular thank goodness but we get to talk to the person and so one of the things that you shared with me was that screening there's been a huge uptick in screening in a certain demographic.
6:01Shawn Stevenson:But the cases of colon cancer are actually happening at much higher levels in a younger demographic. Let's talk about what's going on here. What are some of the most important things that people to know when it comes to colon cancer? Because oftentimes we think it's idiopathic. Unfortunately, even in my college education, it's just like, we don't want cancer to happen, but there are certain underlying components that dramatically increase our risk. Let's talk about that. Yeah. I mean, you know, starting with the, with the epidemiological numbers, um, fortunately, you know, and this has really been the success of the colon cancer screening, the very aggressive promotion of that.
6:48Um, there has been a decrease in adult colon cancers and the complications from it. So if you catch it early, obviously, you know, when it's still just a polyp, before it transforms into malignancy, if you catch it early, there won't be any major consequences. And I think this is largely due to this colon cancer screening program. And colon cancer screening has been done in two ways. stool tests, famous hemo called school tests that we did basically with every physical exam. You would do a rectal exam and have a liquid that you put on the stool sample and you could detect if there's any blood in it, occult blood in it.
7:41Then there was a development of genetic tests also in the stool, which became more sensitive And then there's colon cancer screening with colonoscopies. And that has become, I would say, for many of my colleagues in gastroenterology, so the main source of income, really, and for hospitals. And the combination of these, I think, has slowed this epidemic of colon cancer that we saw before. So why do we have that situation that, you know, first of all, why was it so widespread before in all age groups? Why is it now increasing in younger age groups, even down into the 30s?
8:31I mean obviously genes haven't changed you know genetics is always a risk factor if you are in a family that has a history of colon cancer or any kind of malignancies then you're the high risk and you should definitely be more aware of the risk of developing yourself but why is it happening at an early age um there's got to be something environmental going on and something that has changed I would say in the last 30 years or so or 20 years we don't know exactly what that is I mean I would say diet being very high on the list here uh but it also could be a range of things from the microplastics to any of the the hidden chemicals that are mixed into our food supply you know from from glyphosate which is being used in higher and higher concentrations so I don't think we have the answer the general and this is what the you know the microbiome comes in so colon cancer happens in the habitat of well most of our microbes live the trillions highest concentration on the planet really is in our colon we don't see them we don't hear them we don't feel them but they live there in more or less in harmony with our gut and our gut-based immune system but it is and i would always say you know science is moving constantly so right now the status right now, we would say some aspects of the microbiome that sort of predisposes to a low-grade inflammatory condition in the colon is probably the most likely mechanism.
10:32But I should mention again, I mean, we don't know what microplastics or nanoplastics are doing. We have no idea. You know, so there's a few totally black holes in our science of new developments in society. Certainly, the microplastics have increased continuously. You know, like even now, if you're a health conscious individual and, you know, follow the advice to eat more fruits and vegetables, almost all these fruits and vegetables come in plastic containers, you know, and plastic bags haven't disappeared either. So I would say the exposure to plastic has, if anything, has increased despite our worries that it's doing something silently, you know, that is not good for our health.
11:24so I would say overall positive news in terms of fighting colon cancer in adults
11:36shocking news that it's happening in younger people I personally also always have felt so the whole thing about colon cancer screening and gastroenterology people that underwent that that process and it's you know it takes between five and ten minutes to do a colonoscopy people are evaluated now on their skill set you know the faster they can do it the better and um there's basically no time to communicate with the patient afterwards you know So we've lowered the age of screening. I think it's 45 now from 50. But there's not really what I think would be the most important thing, the patient education.
12:24So if somebody has a, you know, a lot of polyps or a semi-malignant polyp or even a colon cancer that's found on the colonoscopy, the most important thing, in my opinion, is the consultation about a healthy diet. which right now it's sort of delegated to dietitians. I think the physicians themselves should be trained. And there's efforts now in medical school that is finally, after all these years and decades without any nutrition education, this finally is happening. But then there's also the matter of time. As a gastroenterologist, are you willing to spend half an hour of time where you could do two colonoscopies and make five times as much money?
13:15Or are you actually teaching the patient what's known? Anyway, so that's in summary the way I look at this area. You also asked me before, does anybody need to get a colonoscopy now at 45 or even earlier? I mean, there are these non-invasive tests, you know, the genetic stool tests. So the hemocode test has kind of disappeared more or less. But the sensitivity of some of these newer genetic tests or molecular tests in stool samples is almost as good as the colonoscopy. You could say a lot of money could be saved for the healthcare system if the initial screening should annual the cheaper tests starting at the age of 30, really.
14:15um and only if if you have a strong family history or if something um suspicious is found like multiple polyps then you should have your colonoscopy which allows you to take a biopsy and
14:32Shawn Stevenson:you know look at the the tissue yeah yeah and it just seems more logical you know if we have less invasive tests that can be done you know again you know one of the things that you really enlightened me to is the capacity for revenue when it comes to colonoscopies. And it's a big driver for supporting the healthcare system in of itself. And so this isn't getting into a conversation about the ethics of the physician. The physician is wanting to help the patients, but the way that the system is structured right now and the cost of running a hospital, the cost of running a private practice, it's structured in a way in the insurance as well, where you have to really focus on the monetary side in order to stay in business.
15:21Shawn Stevenson:And so we're talking about a restructuring of things. And it is possible because just the fact that nutrition is now being highlighted more, which is something that just, we didn't know if that would ever happen. It's happening now, thankfully. So this can be another catalyst. And a big driver of this is individuals like yourself who are, again, speaking from inside of the system and sharing these insights and saying, now that we have this elevated conversation around colon cancer and we've lost some special people in our culture, this isn't a warning sign or an alert sign to run out and get a colonoscopy per se, but we can do some minimally invasive, non-invasive tests potentially.
16:06Shawn Stevenson:And then if there's a red flag, then you can go for the colonoscopy because there's some risk involved with colonoscopies that aren't really talked about very often. Can you talk a little bit about that? Yeah. I mean, if it's done at a reputable
16:22medical facility, I think the risk is really minimal. I mean, people are so skilled now and trained to do these procedures in the minimal amount of time. Yeah, there's medications involved to relax you, and you won't remember afterwards that you had a colonoscopy. That sounds scary in and of itself.
16:46Shawn Stevenson:But it's very minimal risk, but it's not risk-free. Yeah. Let's put it like that. Yeah, I mean, compared to what I would say, when I started practicing gastroenterology, the risk has gone down to, I mean, nothing is zero in medicine, you know, but that would not be a criteria that I would use to make this decision. But I think the ability that we have now to catch people do annual exams, you know, starting in their 30s, because that's where we see these really tragic cases that somebody develops, you know, metastatic colon cancer. I think we should take advantage of these, you know, to the fullest.
17:32Yeah.
17:33Shawn Stevenson:And it's, again, it's far less complicated, far less time required to get these tests done. And then if there is a problem, a warning sign, then we can go to something that's more, you know, kind of comprehensive as far as like a colonoscopy. And so again, we have a lot of tools at our disposal right now, but most people aren't aware of it. And our system is not structured in a way that promotes it. And so we are advocating for that. And most importantly, how do we reduce the risk? And something you share with me years ago, you were talking about the impact of food. And as somebody who is a pioneer in this field, like it for you as well, it's just shocking to see how little you were taught about the impact of diet and you study the organs related to processing our food, you know, the assimilation and elimination of the food that we're eating and not taught about the food that we're eating and the impact.
18:35Shawn Stevenson:And this just came out a couple of months ago. This was published in JAMA Oncology. This came out literally like six months ago, brand new paper. It looked at nearly 30 ,000 female nurses who were under the age of 50. And what they uncovered was that the individuals in the highest quintile of ultra processed food intake had a statistically significant, about 45 % greater odds of early onset colorectal cancer and related issues. Yeah, and that highlights a very important point coming back to this onset in younger, younger individuals. So I don't know exactly if I get these numbers right. I think in general, 40 % of our food intake occurs in the US in a form of ultra processed food.
19:33And I would say the key components of that is high sugar, high saturated fat, high salt, and no or very little fiber. So those are the key ingredient. There's obviously a lot of additive that we don't even know. If you look at, you know, I always use that example on the plane, you know, what the stewardesses offer. You know, it's always the choice, sweet or sour. Do you want, you know, something in a little plastic bag that's chocolate-based or pretzels in quotation marks? and you look at the ingredient list and it's a whole page the one side of this of ingredients that I've never heard before it's all chemicals you know so these pretzels are more chemistry than they're have anything to do with bread or with a pretzel and so in children so I said in adults about 40 percent of food intake in children it's much higher so imagine from the early on you know when I don't know at what age that that really starts but I would say at the age of three or four you know the body is bombarded with these chemicals and many of whom we don't when there's dyes, you know, that's another big topic right now, that have never really been cleared for their safety.
21:20They get this label by the FDA of GRAS, G-R-A-S, generally recommended as safe, but that's a complete, you know, that's an opening. Anything fits into that. unless somebody gets killed from eating it. And so many of these ingredients that are in there that children are exposed to, and I think the percentage is of the total food intake of children goes up to 60 % of ultra-processed food. So that's kind of a good thing what we're seeing right now, you know, with this political movement, you know, make America healthy again. It's one aspect to attack this ultra-processed food component of our diet.
22:15I think the new guidelines have a lot of limitations. I'm not supporting the people that promote it, but it certainly raised the awareness. And if that will change, if in the next couple of years, are you not going to get on the plane these kind of snacks? or not just in the plane, anywhere. You get out of the plane, there's stands with all these snacks. You look at each package and has the same kind of list of ingredients. It may change for conscious people that spend a lot of time thinking about it. But I don't think for the majority of Americans, this is not changing. you know? Yeah.
23:05Shawn Stevenson:Yeah. I mean, that's the thing, you know, we need top down change, absolutely. But the bottom up change is going to be most viable for us. And especially right now in the short term is what, what differences we can make. And speaking of the top down change, as of this recording, there was just some new policy put in place, which again, we don't know when it'll get implemented, if it'll get implemented, requiring hospitals to dramatically reduce or even eliminate ultra processed food availability within the hospital setting, which is shocking. Again, you would never have thought that something like that would happen.
23:41Shawn Stevenson:And it just speaks to, again, there's nothing more powerful than an idea whose time has come. And for us to not focus on the political aspect, just to focus on the human aspect of it. And the fact that we can do better. We know food matters and let's make some differences with our food. And one of the things you mentioned, and by the way, somebody can be eating what science believes to be a perfect diet for themselves and still develop colon cancer. And this, one of the other things that you, I'm so grateful to talk to you about is like, there isn't just this one thing, right? We have a genetic component, we have an environmental component, and there can be things stacked against you that you don't even realize.
24:22Shawn Stevenson:as you mentioned, microplastics several times. There are numerous papers and seeing this connection with colorectal cancer and microplastics. And this was published in scientific reports last year as well. And so this isn't just like a theory. There are multiple things that we're exposed to in our environment. And so many of these things, if you think about it in the relationship with the microbiome, are finding their way into our digestive tract. And so with this being said, So we've got the microplastics potential and being more conscientious about that, how we're cooking our food. It's so easy.
24:59Shawn Stevenson:We have the microwave culture. Pop it in the microwave in the plastic container. We know that that is one of the fastest ways to get billions and billions of microplastics and nanoplastics into your body is microwaving food. Yeah, we use the microwaving in a plastic container. I mean, this is like, it's almost insanity to do this. you know um but it's almost like you know with smoking i mean smoking was around for such a long time nobody really paid attention to it and then it took you know decades of a very hard fight and the government had to step in and i i think you need that kind of uh in i think things are moving faster today because there's a greater awareness and interest in health and wellness and i always wonder, is this really just a bubble effect that we're seeing?
25:53You know, we live in LA and we think, oh, everybody talks about healthy diet. Is this really happening all over the country in small towns, in southern states, in the central of the US? I don't know. You know, I kind of doubt it. I think we have this illusion that there's tremendous progress in our awareness. But in reality, and then there's the cost factor also. You know, if these healthy things are two times or three times as expensive, then it's only a small percentage of the population are able to afford it. Yeah, that part of the accessibility.
26:35Shawn Stevenson:If anybody knows about seasonal allergies, it's me. One of my earliest memories in my relationship with my wife, then girlfriend, was spending time at the ER because I couldn't breathe. Every season, without fail, my allergies would act up and just have me so congested that I was suffering, struggling to sleep at night. Thankfully, I changed my life. I changed my health. I changed what I was eating. And now allergy symptoms are far and few in between. occasionally a cat will irritate me a little bit, but just being able to change the inputs that I'm giving my body. But one thing that I would never do, regardless of my symptoms, is turn to these terrible, dangerous, conventional products on store shelves that are proven to largely be ineffective compared to some of the most science-backed natural allergy prevention and treatment that is now available to all of us.
27:40Shawn Stevenson:One of my go-tos back in the day was a medication-filled nasal spray that was, in fact, habit-forming. Had I had my hands on some more money, some more cash, I would have kept using it and using it. I was using it way too often, and I didn't even realize it. The habit crept upon me. Very, very addictive and very dangerous. Today, what I turn to and what I recommend is a non-toxic, non-habit-forming, science-backed nasal spray that cleanses and soothes our nasal passages, especially during allergy season to help to flush out irritants, soothe sinus irritation, and defend against germs that we inhale.
28:23Shawn Stevenson:What I'm talking about is the Propolis Nasal Spray from Beekeepers Naturals. Go to beekeepersnaturals.com forward slash model right now, and you're going to get 20 % off of their phenomenal propolis nasal spray max. That's B-E-E-K-E-E-P-E-R-S naturals.com forward slash model and you're going to get 20 % off. The propolis is science affirmed to reduce histamine response and defend against germs right on the spot. The xylitol helps to expand the nasal passages to ease congestion and a saline solution naturally clears and moisturizes. And to top it off, oregano oil invigorates your sinuses for a deep, refreshing ability to breathe.
29:10Shawn Stevenson:Many of my friends and family members swear by the Propolis Nasal Spray Max, including my videographer. Say hello, Connor. He's the one who really affirmed its effectiveness. And because of him, I made sure to keep it on our superfood cabinet shelf, our medicine cabinet as well for if any of my family members are dealing with a little something something they need to breathe easier and top all of this off with the propolis immune support throat spray this is something that we use preventatively and also when we need that extra boost to help with allergy symptoms beekeepers now has a great new menthol version of their propolis throat spray but the classic spray is something that i use every day get a couple of sprays in, just that great immune system support.
30:01Shawn Stevenson:Propolis contains hundreds of bioactive compounds, including essential vitamins and antioxidants. It really is remarkable. Again, backed by science. These are the support that I wish that I had all those years ago. Head over there, check them out, get stocked up right now. Go to beekeepersnaturals.com forward slash model for 20 % off. And by the way, Beekeepers is the number one, number one science-backed allergy treatment in the world now found at places like Target, Whole Foods, Walmart, CVS, and Walgreens. Of course, you could pick it up there right now, or as you know, you get 20 % off when you go to beekeepersnaturals.com forward slash model to really stock up.
30:51Shawn Stevenson:Head over there, check them out, And now back to the show. You know, again, we're with this emerging conversation. Thankfully, this is not to discourage getting screened at all. We want to advocate for that. We also want to advocate for understanding we can get more people buying in on earlier screening with these less invasive methods. And we need earlier screening because of the environment that we're in right now. Now, if we're doing a lot of these things where the things that you're talking about, there wouldn't be this need, you know, but right now, this is the way our system is structured and our system is leveraging the fact.
31:30Shawn Stevenson:And unfortunately, you know, it's kind of propping up our economy, not just even the hospitals, right? It's dependent on us being sick. And this is the world that we're living in today. And so for us to change that, it's going to take a lot of collective voices, but it starts with you as an individual and what you're doing with your family. And so we addressed the ultra-processed food issue a little bit, but there are some other components here as well, because again, there can't be this one thing, this one smoking gun. Yeah. And let me just comment on this. So this is something that I sort of focus on this more and more that, you know, a systems biological view of health and illness.
Read the full transcript
32:10So you have like this intrinsic health that our body generates. And we're basically an elaborate machine that evolution has taken millions of years, billions of years to come up with. And it's programmed for health and survival. And one way does it is by creating, being in a state of balance, of homeostasis. That's the ultimate goal of evolution that we are in this. And we've pushed this so far away from that state in many situations by different forces. So diet is obviously an important one, but many other lifestyle factors and mind states, exercise, basically all the major influences that we are exposed to in our society have an influence.
33:14And there's obviously the genetic vulnerability underlying this. So the intrinsic health is something that's determined by our genetic background. Some people are super healthy. We see this with longevity, for example, healthy longevity. Some people live very unhealthy lifestyles and live into their hundreds. um and but it's influenced to varying degrees by these other factors so one person let's say has the good genes but um you know diet contributes like 60 of what we call the variance 60 influence on on but then they're still you know if they're depressed or chronically anxious if they exercise what um um air they're exposed to you know some for each individual they contribute a significant amount but it differs nobody has the same it's not like everybody has 60 diet influence and you almost have to say to ultimately to you know estimate the risk of somebody to develop diseases, we'll have to use AI to enter all these variables and then calculate a risk score for that person.
34:42If you have a very low risk score, you probably don't need to do many of these tests throughout their lifetime. But there's going to be a lot of people that are pretty high in these categories. But this system's biological view of health and wellness and disease, I think, is a key concept. We don't learn this in medical school. You go for one cause and it drills down to one receptor that's overstimulated.
35:17And, you know, talking about the one receptor, so GLP-1 obviously comes up. and we were lucky every once in a while a compound like this comes up that covers many of these factors that contribute to the we still don't know exactly how it works on so many different disease processes could all be a consequence of affecting body weight and metabolism but could also be that it affects many of these other you know what we call the exposome the influences from the environment on our genetic, on our intrinsic homeostasis. But every once in a while that happens. I think it's the exception. It's much more, you know, just looking at food, for example, food is not just one thing.
36:11It's not just the calories, it's not just the fat, it's the different types of fibers, it's the different types of um and there's a tremendous variety of on on each of these there's thousands of fiber molecules hundreds of polyphenol molecules um so to come up with what's still invoked today you know a lot of the influencers they come up with this one magic thing you know if you do this um and generalize it everybody will get benefit from it that's not the case you know So you may be somebody where that plays a big role, but in somebody else, it has not the same effect. I often think about this.
36:54We've done a lot of research on this early life trauma, and that's one of the big risk factors, you know, that predisposes people to chronic illness throughout life.
37:09and you know there's a good example like holocaust survivors who went through undescribable trauma and or war survivors now we have these several wars going on I mean you would think if what we study in the laboratory in the university setting is generalizable everybody who was involved in these war situations or was in a concentration camp would be affected. But there's a lot of Holocaust survivors that live into their 90s and 100s. That's always, and there definitely have not been people that went to the gym every day and, you know, paid attention to their diet. They lived a regular lifestyle, you know.
37:51So, yeah, I think for me personally, this is one of the most important insights and and lessons that i've learned is to look at this truly yeah we call it holistic view of of health and and disease that's not one thing and it's not one remedy and it's not the same for
38:16Shawn Stevenson:everybody yeah yeah thank you for that and it's a as you just mentioned it's a kind of an overall stress load that it's your own blueprint everybody has their unique blueprint and it's going to be different pieces or puzzle pieces that are going to be effective or harmful to different people. And you mentioned earlier, you even said the mind state. With this being said, what is the connection between our thoughts, stress, you know, as you called it, your mind state when it comes to our gut and our microbiome? Yeah, so I want to start with one example where we know a lot about this and this is the increased risk of colon cancer that patients with inflammatory bowel disease also with colitis have and so that's well established what's less well established and you know we've gotten involved in this kind of research over the last yeah 10 years or so how mind states affect the activity of the colitis.
39:27So most gastroenterologists would say, it has nothing to do with stress. It's a gut disease. It's an immunological disease. It has to do with T-cell, with T lymphocytes. But there's pretty good evidence that, for example, an increased stress reactivity that some people have influences how many recurrences of the ulcerative colitis have once they've gone into remission. So a big factor that influences the inflammatory activity in the gut of these people comes from the mind. And so that's pretty clear cut. So we have one. Now, not all these increases, certainly not in young people, even though inflammatory bowel disease is also increasing in younger patients.
40:18So there's some connection. But the low-grade inflammation, that's harder to measure, you know, is asymptomatic. But from animal studies, we know that low-grade inflammation of the colon is a risk factor for colon cancer. So it's quite plausible, given the importance of the brain-gut microbiome interaction. and the role, the prominent role of low-grade inflammation that we have seen in animal models of IBD, you know, I would say there's a definite link between. If this affects, you know, not everybody who is stressed will develop these inflammatory changes in their colon. A lot of people will never know it because they're not going to have colitis symptoms, you know, but it is inflamed.
41:16But we do know from many studies that stress, chronic stress, acute stress, changes the microbiome and engages the immune system through that, you know. It's a good example how mainstream gastroenterology, just like it has happened in IBS before, is kind of very conservative. This idea that if you are chronically stressed, that this affects your colon, and if you also have genetic risk genes, this would increase your risk of developing colon cancer and a bad diet. I think that it's, again, this multifactorial influence on the system, but the mind state definitely plays a role in this, you know?
42:09Shawn Stevenson:Yeah. Thank you for sharing that. Because again, we tend to put all of our eggs in one basket or we just throw up our hands and, you know, we're just complete victims to the different circumstances that might manifest. And so we know there's a relationship with stress and this kind of inflammatory cascade and also the influence that stress has potentially on our overall gut health, our microbiome. And this is where some of your most recent work is at, looking at the influence that our microbiome has on the production of different hormones and neurotransmitters and the influence that this can have on our cells, on our DNA.
42:46Shawn Stevenson:And so this is what I want to talk about next. I want to ask you about this emerging work with the astrobilone. Yeah, I mean, the reason that this conversation has only started recently reflects another thing of our society that, you know, that women's health has not been viewed equally important as men's health. You know, many of the clinical trials have always been done to males, also in animal studies, because it's easier. You have to have twice the sample size, more expensive to do males and females. so it's kind of amazing that you know half of the population undergoes menopause and perimenstrual symptoms and that it's taken us so long before this has become and it's still not mainstream you know it's not so this strobilom it's it's a group of microbes that is involved in the in the reactivation and recycling of of estrogen i should also say testosterone and many other substances that the liver excretes so you know the liver is our main cleaning organ in the body together with the kidneys but in the liver a lot of processes this happens that molecules that are no longer needed, that have performed their purpose, are modified on a molecular basis, which allows them to be excreted through with the bile.
44:22And the bile empties into the small intestine and then goes down, you know, and then ultimately you would think a simple like if an engineer had designed this they would just say okay all this is targeted for excretion but but not not in the body you know in the body you have this group of of microbes that have a specific enzyme called beta glucuronidase which takes off that molecule that the liver added to make it excretable so it's it's kind of going against what the liver wanted to do, you know. And then these molecules, once you remove that sugar component, becomes water soluble and can be reabsorbed in the end of the small intestine and in the colon back into the circulation.
45:15So this is a significant source of estrogen molecules and testosterone molecules in the body that was already scheduled for excretion, but then the microbes saved it, and it's being reabsorbed. In general, this process is a beneficial process both for us. you know it as long as the ovaries are the main producers of estrogen or
45:52estradiol the main you know the main estrogen molecule it's not that important makes up about 10 but once the ovaries shut down and nobody can change that or wants to change it then it becomes the only, the main source of estrogen in a woman's body. And it's variable. Shutting it down is a universal biological process that affects all women, but the amount that's being recycled depends on what kind of microbial ecosystem or composition each woman has. So some have a very powerful system, So they have higher estrogen levels after menopause. And in others, it's almost non-functioning. And so they have a lot more symptoms.
46:47And so a colleague that I'm working with at UCLA, Dr. Meriwether, very smart guy, which you can tell because he did his undergraduate work in philosophy as a philosophy major. so for the very few physicians or researchers that has that background but I love to talk to him because he always has these amazing ideas that we could actually engineer microbes that have the special capacity that have more of this beta-glucuronidase so they will be more efficient in doing this recycling and you it would be personalized you would give this to women they have a lot of symptoms so instead of hormone replacement therapy you would basically just give them a probiotic that would stimulate the recycling of the estrogen i mean it's an amazing idea i think but it also you know it has a benefit potential benefit for men because obviously so many people take you know testosterone supplements um because you could manipulate that level as well, you know, with a different type of, so it had to be a different microbe that is specialized on.
48:06So what I said about this enzyme, this beta-glucuronidase, there's hundreds of different subforms of it. Some specialized for estrogen, some specialized for testosterone, some specialized for other chemicals that we're excreting. So you could But ultimately, David has that future plan, which I think is one of the most exciting things that I've heard to create specialized bioengineered probiotics that will allow you to improve your hormone metabolism. You know, I mean, it's and I think this approach, I mentioned this to you earlier.
48:56I think the estrobilom is an exception to this, but when it goes about diet, I always say we wouldn't need to do any more research because we know all the answers already. what would be the optimal healthy lifestyle for health and wellness and prevention of disease, even in our contaminated modern world. But science will not be happy with that. And you can't make that much money with just recommending how many apples you have to eat per day and how much fiber.
49:39but there are developments going on that I think are going to revolutionize the healthcare system how long they will take some of them are already here give you two other examples so one is the strobilom and being able to influence these reactivation and recycling of hormones the other one would be bioengineered fibers you know there's thousands of fiber molecules so when we talk about fiber we think this is one one molecule that you have to and so a lot of people do this you know they most of these commercial products that say you know you increase your fiber intake take it's it's one fiber type but the microbes are specialized in all these different fibers so when you eat a healthy plant-based diet you you deliver these thousands of different molecules and it forces your microbial ecosystem to add more and more specialists that can handle these different fibers so the more diverse your plant-based diet is the more diverse your microbiome will become because you need all these guys to to break down the fiber into you know often it's the same end result is short-chain fatty acids it's health promoting molecules you know butyrate is sort of most well known but that's another so there's a company called OneBio that has just launched their first product.
51:17So they take natural fibers and slightly modify them and make them water-soluble. And they've created what they call a glycopedia, which is a collection of hundreds of different fiber molecules that are all slightly manipulated. it so they can all so you can take a teaspoon put it in in your water and you won't even notice that you're now adding 20 grams of of one type of fiber to it you can add four teaspoons of different types of fibers and then you have this variety as you would get by eating you know 30 different vegetables a week um so this also has a revolutionary potential you know because I doubt that people will really dramatically change their dietary habits, the majority, to go to that what's currently, you know, considered the gold standard, 35 vegetables, fruits and vegetables a week, different types.
52:24It's feasible. So we are actually practicing this in our own family, but not everybody can do it. May not be affordable for many people. But so I would say, and then there's a third examples of this modifying existing probiotics or microbes. And that's probiotics. Generally, probiotics have been used for treatment of inflammatory bowel disease. And what people have noticed, the minute you stop taking them, they're basically gone from your gut. you know they they're not able to colonize your your gut particularly inflamed areas if you have ulcerative colitis they won't stay there so a company and startup company in in vancouver that i've been affiliated with they have developed um you know bioengineered probiotic taking a very commonly used probiotic made a small genetic change in that so now it's actually thriving from these inflammatory mediators it it feeds on these inflammatory meters so it's it goes if you swallow one of those probiotics it homes into that area of inflammation will only live there as long as there's inflammation because that's when it gets its nutrients, and it will die off once the inflammation is gone.
54:01So also a completely revolutionary way of treating inflammatory bowel disease, for example. These are just like three examples I gave you, and I think right now, I consider myself a big fan of probiotics. Not sure. You know, I think if you like them, if you feel good, take them. But it's not a dramatic effect, you know. But these new things that are coming down the pipeline really revolutionize, you know, what we can do with fairly natural means. You know, it's not like taking a new chemical. It's taking an organism that lives in your gut and slightly modifying, you know, its properties.
54:47Shawn Stevenson:Have you noticed that a lot of skincare products are now adding green tea extract to their ingredients? And for good reason. A review of 20 studies published in the journal SkinMed revealed that green tea is effective in reducing acne, dermatitis, warts, keloids, rosacea, and many other skin issues. This is incredible. But the biggest benefits were seen when green tea is consumed versus being utilized topically. And the very best source of green tea is matcha green tea. Now, matcha is out here heavy in the streets. People are becoming matcha girlies, matcha boys. All right. But the traditional matcha is being distorted a little bit.
55:34Shawn Stevenson:It's being Frankensteined up a little bit. But the traditional matcha is absolutely overflowing with unique benefits, including benefits for our skin health. Now, here's the rub. There's a ton of different pseudo matchas out there, low quality matchas. And for myself personally, there's only one matcha that I drink and it's quadruple toxin screened for purity. and is 35 % higher in L-theanine, which is clinically proven to help to reduce stress-induced skin irritation. Absolutely amazing. The only matcha that I drink is the Sun Goddess Matcha from Peak Life. Head over to peaklife.com forward slash model and you're going to receive up to 20 % off their phenomenal Sun Goddess Matcha plus all their other award-winning tees.
56:31Shawn Stevenson:And in addition to up to 20 % off, you're also gonna get access to a free starter kit that includes an electric frother. Now, I'm about that froth life. I use my frother every single day. And to top it all off, you get to try Peak Tees risk-free with their 90-day money-back guarantee. So again, head over there, check them out, peaklife.com forward slash model. That's P-I-Q-U-E-L-I-F-E.com forward slash model for up to 20 % off plus some other amazing bonuses. This is the real matcha. This is what matcha was always meant to be. Nothing added, no preservatives, no funky sugars, no artificial sweeteners, just the very best matcha green tea in the world.
57:19Shawn Stevenson:Head over there, check them out, peaklife.com forward slash model for up to 20 % off. And now back to the show. Yeah. You told me years ago about your skepticism about the probiotics out there, supplemental on the market. And again, it just makes sense just not being able to have the capacity to really colonize and really change things in a notable way. And you got to keep taking them. And also some people, again, it could be an end of one experiment where they do find relief or whatever the case might be. But this is one of the reasons we don't have really conclusive data about like supplemental probiotics.
57:54Shawn Stevenson:We've got far more data on prebiotics, right? And being able to provide the fiber types for our bacteria to do what they are designed to do, which is to create these chemicals in us for us. And this speaks to the benefit when we are talking about the astrobilone as well, just to step back to that really quickly. This is revolutionary. Like this is one of those things that should really grab our attention because we have been kind of programmed or maybe undereducated about estrogen, not maybe, definitely. And also just seeing it strictly as this is just an ovary related thing where we know that estrogen is being produced.
58:39Shawn Stevenson:Men don't have ovaries, but we have estrogen. All right? Estrogen is being produced by other cells and tissues and organs as well. And the relationship with the microbiome and the gut should really make us all stand at attention. Like, whoa, wait a minute, hold on. And there are things that we can target with the microbiome that could potentially help to provide relief from estrogen-related decline in the case of perimenopause and menopause. and also in the domain with men with testosterone, the same thing. So how can we keep more of these beneficial compounds around? Because what we don't get educated about is our gut is heavily related to the processing, the removal, digestion, I would say, of these hormones and also recycling of these hormones.
59:32Shawn Stevenson:And so why are we not paying attention to this? I think it's a new it's a new philosophy in medicine quite honestly and if you talk to many of my colleagues about this they would have never heard about it you know it's become a very hard thing in the startup phase because startup scene you know where a lot of people are now realizing wow just this has the potential is huge you know and there's a lot of investment money that goes into it but the mainstream medicine and science has not really embraced that yet. Yeah. Well, again, thank you because you're changing this and, you know, conversations like this reach a lot of people and a lot of practitioners as well, just to start to investigate this more.
1:00:21Shawn Stevenson:And, you know, obviously there's a incredible domain available for bioidentical hormone therapies. What if this, this is beyond bioidentical when your body can produce it in you for you by addressing your microbiome and addressing your gut so it's pretty cool and there's one there's one advantage you know understanding this there's very little research so far on the testosterone part of this recycling but you know it's it's well known taking testosterone in injections or in any supplementary form it will affect your own system so it will compromise it's hard to get off them i mean not that i'm taking them but i've heard people talk about it it's hard to get off it if you generate these with your natural mechanisms you probably won't have that withdrawal effect you could always stop it you know because it's not like adding a boost that's unphysiological so that's another advantage i think of using the body's own wisdom and the microbial wisdom combined to come up with these new therapies.
1:01:33Shawn Stevenson:Amazing. Well, we've already covered a lot of ground. And we started off this conversation with addressing, again, this highlighted conversation of colon cancer. And the very best form of treatment is prevention, you know, and just doing what we can, stacking conditions in our favor. And obviously diet is a big component of that. It's not everything, just to be clear again, but this is one of those things that we know has a big influence and we can influence it. And having you here, what would be three dietary targets or dietary principles for us to follow to help to reduce our risk of developing chronic illness like that?
1:02:25You would have to go back to really to the microbiome. So right now, I think, you know, we talked about this earlier, sort of a commonly discussed theory is that it's a low-grade inflammation that microbial interaction with the immune system in the gut creates. And so the standard American diet is prone to create this low-grade inflammation. So I think it's not one simple thing. It's definitely, you know, eliminating the ultra-processed foods with the sugar. And for a lot of people, this would be number one for things that we know. You know, we can't do much about the chemicals. Well, you can, if you have access to regenerative organic agriculture products, you know, on farmers markets, it's definitely another way of doing it.
1:03:29because there's so much in the soil. You may think about, you know, if you eat these vegetables that are, you know, that are grown in a natural environment, well, they are exposed to their own microbiome, you know, which the chemicals that we put in the soil, I mean, it's a little sort of a diversion. chemicals that we put in the soil and the chemical fertilizer is suppressing the microbiome of the soil, which is a major source of stimulation for plants that produces health-promoting molecules. So if you buy from plant-based food sources from areas that are only grown with chemical fertilizer and never are exposed to this soil microbial communication with the root system, you may be fooling yourself.
1:04:33You know, it tastes good, it looks good, but it's devoid of all the benefits that you normally would get from it. So I think if you can do it, you know, go organic, ideally go sustainable organic and regenerative organic.
1:04:55Certainly, you know, red meat always comes up and it's an ongoing battle. we see it now with the new food guidelines you know that has been both the the the fat the animal fat and the just the red meat has been um you know trivialized as as an important factor so now you know people are being encouraged to increase their red meat intake protein intake and and beef tallow and you know stuff like and butter but there's an extensive literature that's shown that there is an increased risk um you know of of of colon cancer with with with these animal-based meat and dairy products you know it's not um I mean if you have your your steak once a week it's not an issue but if you have your two hamburgers every day and that's your main and your french fries deep fried french fries you are exposed to something that's not healthy for you and that increases your studies that have shown um you know it increases the risk it's amazing I mean coming back to these new food guidelines you know this was a commission that came up of highly qualified people that were invited to contribute to these new guidelines but then the report to the commission was not publicized it was overworked by politicians under the influence of lobbying groups by the the American Beef Council and, you know, the dairy industry and all this.
1:06:43And so they added this component to it, which was not part of the original proposal.
1:06:51So coming back to this, you know, society obviously has many influences on our food quality. But coming back to the simplest thing, what would you do besides going to a largely plant-based diet, ideally coming from organically grown food, eliminating ultra-processed foods as much as possible? I would consider those two the two main factors you know that I would the others play probably not as important roles but yeah like I mean you can't avoid the exposure to plastics you know living in our society just but I think these two things avoiding the ultra-processed diet and going to a largely plant-based diet, which I now call the, it's an ancestral diet.
1:07:54It's not just the Mediterranean diet, even though I have a lot of positive memories and associations about eating this diet in Italy. So for me, it tastes better just because of that. But you go to traditional Asian diets, very similar. You know, you go to the remnants of hunter-gatherers on the Amazon, on the Orinoco River, same thing, two-thirds or more plant-based, even though they're surrounded by animals, they've learned it's not good for them to just live off all the animals around them. So they eat berries and roots and tubers and nuts. So, yeah, I think this ancestral, largely plant-based diet, neither vegan nor vegetarian, understood for ethical reasons, you know, which I totally understand, is pretty the advice that I would give.
1:08:56Shawn Stevenson:Okay, great, great, great. You know, thank you for that. Because again, this isn't pointing to the exclusion of anything, it's pointing to the focus on the things that we know to be most influential for our gut microbiome, which is having those inputs, those data points of different fiber types, right? And again, when I was in school, it was like soluble, insoluble, but there are all these different, every single food has its own unique fiber that it's providing, unique data, right? And we're taking on basically the microbiome, even if you want to think about it like that, of the blueberry or a microbiome of the avocado.
1:09:36Shawn Stevenson:It's like data points to communicate with our own microbes and getting a diversity. And so you mentioned again, we wouldn't have a need for these supplements if we were all kind of living in accordance with how we evolved, which is having, the reason we have all these different microbes is because we had traditionally had all these exposures to different things. But over time, and you see this with hunter gatherers, their diversity of their microbes versus the average American is dramatically different because we are no longer providing those inputs. And so making it a mandate, as you mentioned, one other thing you want to throw in here that you talked about briefly is the exposure to chemicals in our food as well.
1:10:17Shawn Stevenson:And if we can do what we can to, again, if the accessibility is a priority for us to find accessibility, organic, regenerative farming, these are all things that we can check off. We can start to normalize, but there's controversy around that. Well, organic doesn't really make a difference. it just depends on where you look, because one of the most, we're talking billions of tons has been utilized, chlorpyrifos, a pesticide. We know that it creates havoc with the microbiome. It's related to all these different birth defects and chronic diseases, and it's been caught up in red tape, you know, because also our food system can become reliant on some of these compounds as well to grow our food.
1:11:10Shawn Stevenson:And it's just like, well, what if we, okay, it's banned. Now we lose all these crops. And so it's not to villainize one particular thing. It's to know better and to work towards that. And that's one of the things that I admire about you as well is like you advocate for us to do that. And so with all this said, where is a good place for people to connect with you, to follow you, to just get into your universe? You've got some great stuff that's coming very soon for everybody as well. Yeah. So since we last talked, you know, gotten into a lot of exciting projects. So the best way to connect to, you know, my world of information and products is go to my website, emronmayer.com.
1:11:57And then it gives you all these channels that you can go, you know, from hundreds of podcasts, hundreds of newsletter posts. There's a lot of information there. We've also created something in the last year together with our son Dylan, this brand, Mayo Nutrition, where we selectively have identified certain areas that are missing in the diet, like polyphenols, so these molecules that plants make to protect themselves against disease and against UV light, against pesticides. and these compounds not as popular in the lay press as fiber. They've been studied in very large-scale NIH, well-controlled studies like flavanol and other polyphenols.
1:13:09So that's one exciting thing. This also, like, you know, one thing that we picked, a natural product, this extra virgin olive oil from 800-year-old trees. I find that so attractive because, so it's unusual for a tree to survive 800 years. They're exposed to extreme heat and UV light and, you know, pests and all kinds of things. So these trees must have had a selective advantage, which are these polyphenols. They have the highest concentration of polyphenols, not just in their leaves, but also in the olives. And so we've identified a product that is third-party tested for high polyphenol content.
1:14:04And our vision of this is to have a whole, you know, store of similar kind of polyphenol-related products that nobody talks about, you know, but that we know has probably the same beneficial effects as fiber does. So that's, you know, in terms of this mayor nutrition branch.
1:14:29Shawn Stevenson:And where can people get this olive oil? They can go to the website. It's mayernutrition.com. That's M-A-Y-E-R. M-A-Y-E-R, nutrition.com. And yeah, so that's, I mean, there's always a limited supply. You can imagine. Of course, right. This is not a mega product, you know, it's... With these, speaking of which, you know, centuries old, these are adaptogenic compounds. these are adaptogenic trees yeah you know they've really found a way to be resilient and so again it's just passing on these traits and picking up these and the polyphenols in particular like you mentioned there's so we there's so much data on this and in particular the impact it has on our microbiome yeah and then so the other two things that you mentioned so because you know my first book the mind god connection has done so well continues to do so well my publisher harper Collins asked me if I would write a 10 year anniversary edition, which I've just completed, it will come out in October.
1:15:38And we've also created a something for the lay public and easily digestible and practical guides to optimal health and wellness, which has both the science but also lots of recipes and and dietary recommendations not just dietary dishes and uh i've done this with a with a um with a co-author because i'm obviously not a not a chef and you know had to consult somebody who who knows this as well so really excited about these two book projects um yeah and back in my mind i i still have this this um this idea that at some point i would like to do a documentary on this concept of the interconnected planet you know which would summarize many of the things the topics we talked about today because this holistic view of the world and our health and diseases affects everything, you know.
1:16:49And we as a society have been very successful with our Western approach of scientific, rational, but limited approach to identify new things. But we've also missed out on a lot of opportunities. Like we talked about taking advantage of this holistic intelligence and wisdom of the system. So if that film ever is going to happen, we have a teaser made of it. But so that's down the line. Dr.
1:17:23Shawn Stevenson:Mayer, thank you so much for coming to hang out with us today. It's always enlightening talking to you. And I appreciate you being a pioneer and pushing these ideas into culture. Because it's not just everyday people that you're impacting. you're also impacting physicians and practitioners and people who are impacting the lives of other people and so the work that you're doing is it's invaluable so i appreciate yeah thanks and uh you know for me also personally the mission that i see for myself at this stage of my career i don't need to publish any more papers you know and i i also don't really necessarily need to lecture to my colleagues in gastroenterology because i mean they're more interested in doing endoscopies and some of these topics that we talked about.
1:18:10But this education of a large segment of the population is definitely becoming my main mission, you know, and whatever I can do to enhance that with, you know, with the media, social media, book publications, and hopefully the documentary film as well. Yeah, that creates my passion at the moment.
1:18:36Shawn Stevenson:Yeah, well, you are appreciated. I thank you so much. The one and only Dr. Emmerin Mayer, everybody. Thank you so much for tuning into this episode today. I hope that you got a lot of value out of this. Keep this conversation going. Please share this with somebody that you care about. Send this directly from the podcast app that you're listening on. Or of course, you could take a screenshot of the episode, share it on social media, tag me. I'm at Sean Model. Tag Dr. Mayer as well. I know that he would love to see the love. This is such an important conversation. We covered a lot of ground today, but again, we need to help to shift our system towards prevention, towards, of course, early detection with non-invasive and minimally invasive testing that we now have available just to get more buy-in from people, to get people in the door, to make sure that our health is on point.
1:19:33Shawn Stevenson:But with this being said, restructuring our current healthcare system is going to be a mighty task to say the least because it is so focused on monetization just to keep everything running as is. And disease prevention is not a very good business model for the way that things are currently constructed. And so we're advocating for change in multiple aspects of this. And also, again, this powerful conversation around the astrobilome and the impact that targeting our gut and our microbiome and the health of our gut and microbiome and influencing symptoms of perimenopause and menopause and also andropause as well when it comes to men's health.
1:20:20Shawn Stevenson:This is incredible and something for us to now, again, you heard it here first, to be able to have our eyes out for coming down in the next couple of years, more information about this. And again, more ways for us to take back control of our health, take back control of our minds and stat conditions in our favor. I appreciate you so much for tuning in. If you enjoyed this episode, please, if you're listening on Spotify, leave a comment, make sure to like this episode and if you're listening on Apple Podcasts, please pop over and leave a review for the Model Health Show. It really does mean a lot.
1:20:58Shawn Stevenson:And of course, you could pop over to the YouTube channel and get to hang out in the studio with me and my guests and share your voice there as well. We've got some incredible masterclasses and world-leading experts coming your way very, very soon. So make sure to stay tuned. Take care, have an amazing day and I'll talk with you soon.
From the publisher
It was once believed that young adults were largely safe from developing colorectal cancer. But the sad truth is, rates of cancer and cancer deaths have been on the rise in younger age groups in recent years. Today, we’re going to unpack some of the environmental factors that could be behind this uptick and how to optimize your diet and lifestyle for a healthier gut.
Dr. Emeran Mayer is a gastroenterologist and neurologist who specializes in the intricate role between the gut and the brain. Today, he’s back on The Model Health Show for an enlightening conversation on the important topic of colon cancer. Dr. Mayer is sharing the risk factors for colon cancer, new innovations in microbiome research, and how to strengthen your gut health.
You’re going to learn about advances in colon cancer screening methods, the optimal diet for a healthy gut and microbiome, and the role your hormones play in regulating your gut and overall health. Dr. Mayer is passionate about taking a holistic role to health, as well as empowering folks to understand the brain-gut connection to make more informed decisions about their health. I hope you enjoy this interview!
In this episode you’ll discover:
How advances in colon cancer screenings have impacted cancer rates. (6:35)
The different methods of screening for colon cancer. (7:16)
Why colon cancer rates are rising in young adults. (8:53)
The connection between processed food intake and colorectal cancer rates. (18:36)
What intrinsic health is and how to influence it. (33:20)
How early life trauma can predispose humans to chronic illnesses. (36:55)
What the estrobolome is. (43:34)
Dr. Mayer’s approach to taking probiotics. (54:13)
Dietary principles that can help you reduce your risk of developing illnesses. (1:02:51)
The importance of regenerative agriculture. (1:03:20)
How eliminating ultra-processed foods can improve your health. (1:07:15)
Items mentioned in this episode include:
Beekeepersnaturals.com/model - Save up to 30% on natural remedies!
Piquelife.com/model - Get exclusive savings on bundles & subscriptions!
Mayer Nutrition - Shop gut health supplements, organic olive oil, and more!
Books by Dr. Emeran Mayer - Learn more about the brain-gut connection!
Connect with Dr. Emeran Mayer Website / Newsletter / Podcast / YouTube
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This episode of The Model Health Show is brought to you by Beekeeper’s Naturals and Pique.
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