Heart Disease Kills More Women than All the Forms of Cancer Combined

15 Sep 2026 · 48 min · 24 chapters

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In short

Women’s cardiovascular disease—why it kills more women than all cancers combined, why symptoms are often missed or dismissed (as anxiety/acid reflux/menopause), and how to reduce risk earlier using prevention, stress management, and resilience.

Guests (backgrounds)

  • Dr. Tara Narula: Board-certified cardiologist; journalist and chief medical correspondent at ABC News; New York Times bestselling author of The Healing Power of Resilience.
  • Kayla (29 at onset): Special education teacher and fitness instructor; had a STEMI at 30 despite no traditional risk factors; later diagnosed with heart failure due to SCAD.
  • Stacey: Black woman in Chicago; struggled with weight, inflammation, plantar fasciitis, prediabetes, hypertension, and high cholesterol; started a GLP-1 (Oct 2024) and lost 80 pounds.
  • Danielle: New York patient; symptoms were initially attributed to menopause/weight; Dr. Narula ordered testing and she credits timely care with saving her life.

Key claims

  • Cardiovascular disease is an umbrella term (heart attack, atrial fibrillation, heart failure, valve disease, stroke) and is the leading cause of death for women.
  • Women often wait longer, are underdiagnosed/undertreated, and may have atypical symptoms.
  • Pregnancy complications (preeclampsia, gestational diabetes, early birth, small-for-gestational-age) predict future cardiovascular risk.
  • Chronic stress can worsen inflammation, plaque rupture risk, arrhythmias, and blood pressure.
  • Resilience = “bounce forward” after loss/illness; acceptance enables a new life.

Notable examples

  • Kayla’s 100% blocked left heart artery, three stents, cardiac arrest, ECMO transfer, and SCAD.
  • Stacey’s GLP-1 results: 10-pound loss in week one, pain/inflammation relief, 80-pound total loss, normalized blood pressure and improved cholesterol.
  • Danielle’s “new birthday” after a procedure she says would have been fatal within two weeks without Dr. Narula’s attention.

Written by AI. May contain mistakes. Listen to the episode to check what was said.

Chapters

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Heart Disease Impact on Women

0:06 to 0:42

Discussion on the rising rates of cardiovascular disease in younger women.

“I had just turned 30 and I taught a fitness class that morning and I was experiencing a STEMI heart attack.”

Oprah Introduces Dr. Tara Narula

0:42 to 1:42

Oprah introduces Dr. Narula, highlighting her expertise and the importance of heart health.

“So great to be here with you on the Oprah podcast.”

Understanding Resilience

1:42 to 3:24

Dr. Narula defines resilience and its significance in overcoming challenges.

“And if you're a woman listening, please pay strict attention.”

The Importance of Women's Heart Health

3:24 to 4:46

Discussion on the significance of being aware of women's heart health challenges.

“And I think I love your definition because so many people want to go back to the way things were, whether it's in regards to your health or whether it's in regards to relationship.”

Recognizing Heart Attack Symptoms

4:46 to 6:08

Dr. Narula explains key symptoms of heart attacks in women that are often overlooked.

“So I want to just jump into some of the basics about women's heart health for you all.”

Advocating for Your Health

6:08 to 8:16

Encouragement for women to advocate for their health when feeling dismissed by doctors.

“So by far and away, the most common symptom in women of a heart attack will be chest pain or pressure, okay?”

Pregnancy and Cardiovascular Risk

10:01 to 12:10

Discussion on how pregnancy affects cardiovascular health and related risks.

“This is another stat that really was really enlightening for me.”

Kayla's Heart Health Journey

12:10 to 14:01

Kayla shares her personal experience with heart health issues at a young age.

“that cardiovascular disease is impacting younger and younger women.”

Surviving a Heart Attack: A Personal Journey

14:01 to 15:11

A woman shares her harrowing experience of a heart attack and recovery.

“By the time I was taken back, I had already had 100 % blocked heart.”

Understanding SCAD and Its Impact

15:12 to 16:48

Discussion on Spontaneous Coronary Artery Dissection (SCAD) and its effects on women's health.

“attack was SCAD, which stands for Spontaneous Coronary Artery Dissection.”
Show all 24 chapters

Redefining Strength and Resilience

16:49 to 17:41

Exploring the concepts of strength and resilience following a heart attack.

“It was grieving a version of myself that I had lost and learning how to trust my body again and managing that fear.”

The Effects of Stress on Women's Heart Health

17:42 to 20:06

Dr. Nerula discusses how chronic stress impacts cardiovascular health in women.

“Nerula, from a cardiovascular perspective, how do chronic stress, constant busyness, and just the pressure for women to constantly keep it all together affect their heart health?”

Navigating Grief and Acceptance

20:07 to 22:26

A conversation about the emotional journey of accepting heart failure and finding a new normal.

“which is to say, yes, we have the stress response, but we also have the power to get back to homeostasis, to turn it off, to dial it down by activating the resilience that we have inside of us.”

The Power of Acceptance and Moving Forward

22:27 to 25:00

Discussing the importance of acceptance in managing health challenges and moving forward in life.

“I fought them on my medications for a while.”

Heart Disease Statistics Among Black Women

25:01 to 25:50

Highlighting alarming statistics about heart disease prevalence in black women.

“but the one of the major factors in being able to move forward in your life, whether it is a medical or any other crisis, is getting to the point of accepting that this is what it is.”

A Personal Story of Struggle and Health

25:51 to 28:00

A woman's journey with weight loss and health issues in the context of family history.

“70 % of Black women will have hypertension, 70 % will have obesity, And almost 25 to 30 % will have diabetes.”

Struggles with Weight and Health

28:00 to 29:58

Discusses personal struggles with weight, menopause, and health challenges.

“And so I, you know, I tried every diet, done everything and told my doctor, I was like, hey, you know, something's not right.”

Benefits of GLP-1 Medications

29:58 to 32:55

Explores the health benefits of GLP-1 medications and weight loss.

“80 pounds is that is that is pretty phenomenal.”

A Life-Saving Diagnosis

32:55 to 38:15

A patient shares her experience of receiving a life-saving diagnosis from a doctor.

“Not to mention how good you feel about yourself.”

Understanding High Blood Pressure

38:15 to 40:33

Emphasizes the importance of monitoring and managing high blood pressure.

“I don't think everybody understands how that impacts everything else in your health, particular cardiovascular health.”

The Power of Purpose and Resilience

40:33 to 42:00

Discusses the importance of purpose, spirituality, and resilience in health.

“of that contributes to your having a meaningful life and also beating the odds of risk of heart disease.”

The Power of Resilience

42:00 to 43:45

Explore the significance of resilience in overcoming life's challenges.

“And some of us find it based on what happens to us.”

Life's Essential Eight for Heart Health

43:45 to 44:49

Learn about the American Heart Association's checklist for improving cardiovascular health.

“and I will have to say that the American Heart Association created what they call the Life's Essential Eight.”

The Importance of Stress Management

44:49 to 45:50

Understand why stress should be a key focus in heart health discussions.

“If we find things early, if we get on the road for prevention for women, for people, we can have a huge impact.”
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Transcript

Automatic transcript. May contain errors.

0:00This episode of the Oprah podcast is presented by our partner, Geico. We're starting to see headlines that cardiovascular disease is impacting younger and younger women. I had just turned 30 and I taught a fitness class that morning and I was experiencing a STEMI heart attack. Wow. Three stents were placed in my heart. I then went into cardiac arrest and I needed multiple rounds of CPR and shocks. They told my husband I needed to be life-flighted to a different hospital. Well, nearly 60 % of black women just 20 years old and older are living with some form of cardiovascular disease. That stat knocked me out.

0:44That is a wake-up call. Hi, everybody. So great to be here with you on the Oprah podcast. Think about this. during the time that you listen to this podcast, roughly 35 women in the United States will have a heart attack, 35. We hear this stat all the time that heart disease is the number one killer of women in America, killing more women than all the forms of cancer combined. And yet it seems like it gets nowhere near the urgency and focus of breast cancer or menopause or infertility as it relates to women's health. And now we're hearing that it's impacting younger women in higher numbers. So I asked one of America's leading cardiologists to come on the podcast so that you can have all the latest and essential information to protect your one and only heart.

1:43And if you're a woman listening, please pay strict attention. Dr. Tara Narula is a board-certified cardiologist, journalist, chief medical correspondent at ABC News, New York Times, bestselling author of The Healing Power of Resilience, A New Prescription for Health and Wellbeing. Glad to have you here on the porch. Thank you so much. Oh, I love this idea of the healing power of resilience. And I want to hear how we can actually tap into that. I want to know what you how you define resilience. It's a great question. And when I was researching the book, Oprah, a lot of the psychologists have different definitions of what resilience is.

2:24And so for me, it was important to come up with my own based on my experience as a physician, as a human, as a journalist. And so I love the concept of resilience being the idea that you never ever go back backwards, back to who you were. So I loved this. I love this. And I like to frame it in the idea that you bounce forward to something new. I use the analogy in the book of Michelangelo, who says that he carved the marble until he set the angel free. And so this concept that we are the marble and we are the angel, we're constantly evolving and being shaped by what happens to us in life, but that what happens to us cannot pause us and freeze us in time and paralyze us.

3:04We can actually grow and move forward and create a beautiful life, a life where we can thrive and grow and suck all the meaning and joy out of every single day. And that is my hope for my patients, for people who read the book, is to say no matter what life throws our way, no matter what challenges, we can bounce forward. We have that skill. And I think I love your definition because so many people want to go back to the way things were, whether it's in regards to your health or whether it's in regards to relationship. I say to my friends who are going through, you know, divorce, you know, you will create a new normal.

3:40That's right. And you will come through it and you will not be the same person you were. You're going to be a stronger person than you were. And that's part of what resilience is, whether it's relationships or whether it's your personal health. That's exactly right. And the book is really meant for anyone going through any challenge because at some point in time, we will all go through something. Whether, as you said, it is a divorce, a loss, a death. A disappointment. A disappointment. Or a health challenge. Yes. And, you know, I see this in my patients when I walk in the room and they have had a stroke and they can't move the right side of their arm or they've had a heart attack and they have heart failure.

4:16And they look at me and they wonder, when am I going to be myself again? This is what they ask me. And I tell them, you will never, ever be yourself again. But you can be. We won't be that self. We won't be that self. You will be another self. Another version of yourself. That can still have quality of life and meaning. That's what people want, Oprah. They want to still be able to enjoy every day, to see the sunset, to call their best friend, to really, as I said, take all the pure enjoyment out of every single day they can have. So I want to just jump into some of the basics about women's heart health for you all.

4:51And I know you've heard it, but I want you to actually take it in, not just listen to what we're saying, but to absorb. You know, I didn't realize that heart disease is really an umbrella term until reading your book that many things fall under this. So what falls under this? So cardiovascular disease is a broad term and it encompasses things like heart attack, electrical problems like atrial fibrillation. It encompasses heart failure, valve disease, stroke. So it's all of these things under this big umbrella term. And as you said in the opening, it is the leading cause of death for women in this country.

5:31One out of every three women, Oprah, are dying from cardiovascular disease. These are our sisters, our friends, our mothers, our colleagues. And I think it just has not become personal enough for people. I think that there is a lack of awareness. And what I would hope that every listener would do right now is to close their eyes and picture the faces of the women that they love. because these are women that we're going to lose, that are not going to have the birthdays with us, that are not going to go to the graduations. We're not going to be able to be at their wedding. So all of those moments in life with the women that we love, they can be gone in a heartbeat.

6:08I think, and also because so many people misread what it means to have a heart attack or have heart disease because everybody thinks, unless you have the burning sensation in your arm or unless all of a sudden you can't breathe, that it's not a heart attack, but the symptoms show up in so many other different ways. Can we talk about that? Absolutely. So by far and away, the most common symptom in women of a heart attack will be chest pain or pressure, okay? So first of all, that's important to know, but it doesn't have to be the type of very sharp, strong chest pain that makes you fall out of your chair.

6:42It can be a sensation like my bra is just on too tight. I feel something heavy or pressure or tightness or squeezing here. It can also look like jaw pain or neck pain or shoulder pain. Or stomach pain, you said. Or stomach pain. And then when we think outside of the chest pain, there are other symptoms that women can have, like shortness of breath, right? I'm a little bit winded when I go up the stairs or up a hill or when I'm walking fast. It can be fatigue, which is another one. Yes, I start to feel fatigued and people just ignore it. They just ignore it. I can't exercise as much as I used to.

7:16I'm nauseous. I'm breaking out into a cold sweat. I'm dizzy. I'm feeling my heart skipping or fluttering or racing. Any or all of these symptoms. I always tell women it's really important to pay attention to because you may be told that it's acid reflux. You may be told it's all in your head or it's anxiety. And I always say it's so important to rule out. I hear a lot of women are told by their doctors that their symptoms are anxiety. So many women and it's missed. And the problem is when those heart cells die or those brain cells die, you can't get them back. But if you can catch cardiovascular disease or heart disease early with preventive measures, we can prevent the actual events.

7:55So what should a woman do when she feels like something's off, but I've told this doctor and I've told this person, I've said this, but I still feel like I'm being dismissed. You have to listen to your body and listen to yourself and you need to find a doctor that listens to you. And if that means getting a second opinion or a third opinion, that's what you have to do. I see a lot of women who come to me and say, I was blown off by the last doctor I saw. I was told that it was all in my head. You have to advocate and push and fight for your health, and you have to trust your body. Our listeners tell us that the podcast is resonating with you and is serving as a bright spot in your day.

8:35That means a lot to me. So here's the thing. I would really appreciate it if you like and subscribe to the Oprah podcast on YouTube or wherever you podcast. It's just a quick tap of the subscribe button, and that way you won't miss an episode in your queue. You don't have to pay anything. I know subscribe usually means you're paying something, but this time it means you just are notified when there's something new. There are many more to come that we're excited about, so thank you for watching and listening. Those of you who watch the Oprah podcast or listen to us, you know, every story we share, every guest we welcome is chosen with purpose.

9:13And when people share their stories, we're reminded that we're not alone in this journey called life. As the official insurance partner of the podcast, the folks at GEICO understand that the way we move through life and who we move through it with matters. And I know that life starts to move even faster as a new school year begins. Fall routines get underway, the calendar fills up, whether you're waiting in the school pickup line, loading up the car for a weekend getaway, taking a quiet drive home after a hard day, or cheering on your son or daughter from the sidelines. These moments remind us the road is not always a straight line.

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10:06This is another stat that really was really enlightening for me. Women who have given birth, you say, pregnancy acts as a crucial stress test or window into a woman's future cardiovascular health. How so? So I think it's, first of all, important for women to understand that we have risk factors, Oprah, at every point in our life, starting as early as 11 or 12 years old. If you had early periods or irregular periods, you are at increased risk of cardiovascular disease. That's as an 11 or 12 year old. Then we think about what happens to women in their 20s and 30s. There are female specific risk factors.

10:44So you're at risk for cardiovascular disease? If you had early periods, which of course most women don't know. When you think about your 20s and 30s, you may have heard about high blood pressure and diabetes, but let's talk about female specific risk factors there. and those would include polycystic ovarian syndrome, inflammatory bowel disease like Crohn's or ulcerative colitis, migraine, autoimmune conditions like lupus, rheumatoid arthritis, and even psoriasis, a skin condition, and then pregnancy. So what happens during pregnancy is a marker of future risk. So if you have had preeclampsia, eclampsia, gestational diabetes, a baby that was born early, miscarriages, a baby that was small for gestational age, These are markers of future risk of cardiovascular disease.

11:29And unfortunately, most women don't get told this while they're pregnant, and they don't get connected to a cardiologist after to make sure that they know how to manage that risk. We think about, in a woman's 30s, 40s, 50s, breast cancer, for example, and the treatments they might receive, like radiation or chemotherapy, that can damage the heart. Are you more prone to cardiovascular risk after a pregnancy? So if you have had one of those things that I mentioned, yes, you are at increased risk of cardiovascular disease. And then we think about early menopause and menopause. So this whole arc of a woman's life matters in terms of figuring out her cardiovascular risk.

12:09So like I said before, we're starting to see headlines that cardiovascular disease is impacting younger and younger women. Kayla is joining us on Zoom right now. She was just 29 when she started feeling that something was wrong. Hi, Kayla. Welcome. Thank you for having me. Yes. What happened at 29? Yes. In 2022, I was a 29-year-old special education teacher. I lived a very busy life. I was also working at a tech startup on the side. Wellness was very important to me, so I was also a fitness instructor on top of that. So like many women, juggling a lot of competing priorities, that would be very stressful.

12:48In May, I started to experience pain between my shoulder blades. It was on and off at first, and then it eventually radiated to my chest. Where exactly could you point? Let's see. Between your shoulder blades? Yep, in between my shoulder blades. So turning around, right back here. And then eventually it did radiate to my chest, but to the point where it was very dull. Like it wasn't having a heart attack feeling. So when I had gone to the doctor, because I am otherwise healthy and no traditional risk factors, I was told that it was likely attributed to my anxiety that I'd already had and acid reflux, which I had never experienced before.

13:33even though I did know something was wrong. In August, the symptoms were much worse. I was exhausted constantly, feeling very weak. And August 22nd, I had gone to the emergency room because by that point, I also experienced jaw pain. Wow. All the things that you described. Yeah. At that point, I had just turned 30 and I taught a fitness class that morning. So I did not fit the picture of someone having a heart attack, so I was not immediately taken back. By the time I was taken back, I had already had 100 % blocked heart. The entire left side of my heart was shut down and I was experiencing a STEMI heart attack.

14:15Wow. I was immediately rushed to the cath lab. Three stents were placed in my heart. I then went into cardiac arrest and I needed multiple rounds of CPR and shocks. At that point, they told my husband I needed to be life-flighted to a different hospital that has ECMO, which is the highest form of life support. It essentially acts as your heart and lungs when your body needs to rest. So at that point, I truly believe there is a - First of all, we're lucky to have you here. God bless that you're here. That you're here. Wow. Yes. There's definitely a mind-body component. I think that came into play at that point because ECMO gets a pretty bad rap.

14:59People don't come off ECMO. It's usually a last-ditch effort. And my ability to come off ECMO, I do believe it's when my mind-body connection kind of came into play. I did spend a month in the ICU though. The cause of my heart attack was SCAD, which stands for Spontaneous Coronary Artery Dissection. Essentially, it's a spontaneous tear in your artery wall. If it's caught early, it's often managed by medications and then it can heal on its own. In my case, it was not caught early enough. So I thank you for being so open and candid and sharing with us because somebody is listening to us right now, I guarantee, who has been feeling the same thing, experiencing the same thing, and they're like, oh my God, let me get myself to a doctor right now.

15:48Absolutely. And one of the key things that you said here, and Dr. Nerula was agreeing, I see you nodding, is that you felt something was off. You felt something was wrong. Yes. Yes. We as women, we know our bodies best. I think we've all said that right now. Dr. Nerula, you said that as well. And I now live with heart failure. And so my biggest thing, I am more intentional with my life than I ever have been at this point. I, you know, I'm intentional with my time, who I give my energy to now. And I give my permission, myself permission to say no and set boundaries. And my hope is that women who are listening, because we are in a society where we are constantly being pushed, women could give themselves permission to slow down, listen to their bodies, advocate for themselves, because it is really challenging when after the fact you have to grieve a version of yourself, you were talking about it before, that you think that you just want to get back to normal.

16:48And for that first year, it was about survival for me. It was grieving a version of myself that I had lost and learning how to trust my body again and managing that fear. So I think for me, it was over time just really redefining what strength and resilience means in my life. And that meant not pushing through everything and truly knowing when to pause and listen. Yeah. Would you consider yourself, yeah, a model for this book now that you are, you have experienced the healing power of resilience. I definitely have. I feel better now, even though I have heart failure, I feel better now, like I'm stronger now than I was pre heart attack.

17:28And I think that is because I'm so intentional with, again, how I spend my time and who it's with and the decisions I make for myself. I'm truly putting myself first, and I didn't before. I want to know, do you have a question? Do you have a question for Dr. Nerula? I do. I do. Dr. Nerula, from a cardiovascular perspective, how do chronic stress, constant busyness, and just the pressure for women to constantly keep it all together affect their heart health? And what do you wish more women understood about that connection? First of all, I'm so happy that you're okay. And second of all, I hope everyone sees this is the face of cardiovascular disease is what I'm talking about.

18:07It looks like all of us. I think you said a couple other things, which I think are really important to point out before I get to stress, which is that women we say in cardiology have been understudied, underdiagnosed and undertreated. So we know that women come to the emergency room with chest pain, they will wait longer than men. They are less likely to receive guideline, directed medical therapy and treatments. This is a problem. So we need to work on it from the medical establishment side. And then I think what you mentioned about stress is so critical. And to be honest, that was really the impetus in so many ways for writing this book was to recognize how much of a threat stress is to all of us in our daily lives.

18:43And we don't talk about stress. We say it's the amorphous thing that's really bad, but it really truly has an impact on our body, the mind-body connection that you talked about. So stress was designed to help us survive. We have a stress response that's innate, that's built in so that when we see a predator, for example, in the wild, if we're an animal, we have our heart rate go up, our blood pressure goes up, We turn off all functions that are not necessary, like digestion and reproduction. The issue is that we're meant to then turn it off. Once we've escaped something that's chasing us, we're meant to turn it off.

19:14In our daily lives, we are turning on our stress response all the time, every minute, for all kinds of little insults. I got a bill in the mail that I didn't want to see. I may be in trouble with my job. Something happened with my child. And that constant chronic stress is damaging everywhere, but to our cardiovascular system. We turn on hormones like epinephrine and norepinephrine. We turn on hormones like cortisol that increases inflammation. And we have studies that show that stress will increase the ability of a plaque that may be stable in your arteries to rupture. It will increase arrhythmias.

19:49It increases blood pressure. It increases your risk of having not only SCAD, spontaneous coronary artery dissection, that is one of the risk factors, but also stress-induced heart attacks. There's actually a phenomenon of a stress-induced heart attack. So stress is something that we all have to do a better job navigating. And that is why I wanted to write the book about the resilient response that I talk about, which is to say, yes, we have the stress response, but we also have the power to get back to homeostasis, to turn it off, to dial it down by activating the resilience that we have inside of us.

20:23I wanted to ask you, too, because the whole process, you know, Dr. Darula talks about people getting to the moment of acceptance. and I being such a young woman, was it difficult for you at first to accept? And I, you use the word so freely here of I've had heart failure. I have heart failure. I'm a woman who has had heart failure. Was that hard for you at first? Oh, yes. I, as I don't like to be told no for things. And I was very much of that first year in the, I will prove them wrong stage. And grief is not linear. So you at one point think you are proving them wrong. And then of course you have a bad day.

21:06And I think you talked a lot about this at the beginning where you, again, you grieve the old version of yourself because you want to get back to that person, but they no longer exist. So for me being told no was that I couldn't be who I was. And I didn't know for the longest time what the point was. And I think there's a mental health component to this that you have to make the decision to figure out what you want to do and who you want to be moving forward. And I'm still a fitness instructor. I teach something completely different now. And I am so happy. I am so fulfilled because of it. But I had to actively make that decision to move forward and decide what I was going to be after this.

21:51Because being 30 years old and knowing that I had the rest of my life, I didn't want to live it in fear. And that first year was truly that. And it was very challenging. Yeah. I ask it because when I was going through menopause and later discovered that I had a thyroid issue and I remember someone giving me heart medication and I remember thinking, well, I'm too young to have heart medication. The idea of even like having to take heart medication was a reminder that you're not who you think you are. You're not what your body, what you think your body can do. And so when you use the word heart failure so openly, I was wondering whether or not that was a transition for you.

22:34I fought them on my medications for a while. I wasn't in any prior to that. And I had a very hard time adjusting to the fact that I had to take these medications to help my heart's pump function. Otherwise, if I didn't take it, I, we don't know what would happen. And I was like, why does my body have to depend on this to your point? Yeah. And over time though, because there'd be times where I wouldn't take it on time and I would actually feel it. And, uh, now I take my little pill pack everywhere with me. And I think with a little bit of, you know, with the acceptance part of it, I talked about it a lot.

23:16I talked a lot about a lot of my struggles. And I think that actually helped me talk about the dark parts. Yeah. And that also helped me to be okay with being on medication and to find the new me outside of it. But I was very angry in that first year. And Kayla, you're the perfect example, because I'm sure you actually use the word grieving who you were. And I'm sure you went through all of those stages of grief, you know, shock and denial and anger and bargaining, and then finally reach the point of acceptance. And that's when you're able to turn the corner and change the trajectory for yourself.

23:53Absolutely. I fought it for two and a half years because I'm three years out now. And strangely enough, the moment that I reached acceptance was when I realized that, because I was trying to constantly improve my heart, improve my heart's function, your ejection fraction, until I realized something flipped in my brain where I'm like, oh, they are actually focused on making sure it doesn't get worse. And it hit me when I realized that I couldn't, you know, have children. And that in that moment, I was like, okay, well then if I can't have children and my heart, I'm focused on it not becoming worse, what is my life now?

24:31And that acceptance piece was right there. I learned that very lesson I wrote about in the book when I was in medical school and I lost vision in part of my eye. And it was the same story. And it was my mother sending me the serenity prayer. God grant me the - Before you all even knew it was a serenity prayer. Before, correct. And her words really changed my ability to accept that. Listening to the serenity prayer helped me to walk through my own diagnosis. And that's how I know how important it is to accept. Yeah, I'm hoping people will get the book, The Healing Power of Resilience, but the one of the major factors in being able to move forward in your life, whether it is a medical or any other crisis, is getting to the point of accepting that this is what it is.

25:15Now, what do I do with it? Now, how do I use this? Exactly. Thanks, Kayla. Really enlightening. Thank you so much. Thank you. Well, nearly 60 percent of black women just 20 years old and older are living with some form of cardiovascular disease. That stat knocked me out. Yeah. That is a wake-up call. You know, it should be a wake-up call. We need a wake-up call in this country for all women of color because all women of color, Oprah, are at increased risk of cardiovascular disease, but Black women in particular. There's actually a new report by the American Heart Association, and they forecast that by 2050, 70 % of Black women will have hypertension, 70 % will have obesity, And almost 25 to 30 % will have diabetes.

26:01And that's higher than any other group. Higher than any other group. They have the highest rates of cardiovascular disease, the highest rates of stroke and heart failure, least likely to really get treated, diagnosed, highest death rates. Listen to that again. We black women have the highest death rates, highest rates of heart disease, highest rates of diabetes. Obesity and hypertension. Wow. And it's a big, big problem. And we need to do better in this country to address this. Because, you know, there are ways that we have to address it, but we have to understand where this comes from. And where is it coming from?

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26:38Yeah, I think a lot of it is driven by those risk factors, right? So we can get better control in the risk factors. But we talk about this term. A lot of stress, carrying everything, being the breadwinner, repressing all your feelings, not really. Yes. Intersectionality. Yes. This idea that there are social determinants of health, that we are more than just, you know, my hypertension and my diabetes. We are, what is my income level? What zip code do I live in? Do I live somewhere rural? Do I have access to food? Do I face racism and discrimination constantly? So all of that, Oprah - What am I up against in the world?

27:15What am I up against? All of that translates into stress. Yes. Stress that we've been talking about that activates and damages our cardiovascular system. And all of that just sort of embeds within your cells. And there you are. Stacey's on Zoom and she's been nodding. Hey, Stacey, hello, hello, hello. And in Chicago, tell us your story. Thank you so much for having me. I'm so excited to share my story with you. So I am that black woman that you were just talking about. I am married for 38 years to my high school sweetheart. We have six sons and 12 grandchildren. And my weight has been a struggle my entire adult life.

27:53And I knew that I needed to do something about it. My mother had suffered two strokes. So I knew that that was potentially something I was going to have to be concerned about for my future. And so I, you know, I tried every diet, done everything and told my doctor, I was like, hey, you know, something's not right. I'm exhausted. I'm aching. My feet hurt. My ankles hurt. I'm inflamed. Like everything, something's wrong. and my doctor wasn't listening. So I went to a weight loss center and said, okay, maybe they'll listen because this is what they specialize in. Cause I knew I needed to get the weight off.

28:27And, you know, menopause came and she brought 20 pounds with her friend of 20 pounds. And so I said, I need to - Menopause came and brought her friend. And I said, I can't do this. I can't continue to do this. Girl, I can't deal. Yes. No, thank you. We are not participating. So I ended up getting on a GLP-1 in October of 2024, and it was a godsend. I mean, I definitely had all of those things you were talking about. I had the high blood pressure. I had the high cholesterol. Again, the inflammation in my body with the plantar fasciitis, walking around in pain, waking up exhausted after sleep. I was pre-diabetic.

29:10So I got on that GLP-1 in October of 2024. And in the first week, I lost 10 pounds of just inflammation and the pain was gone. Like my feet, I had gone through cortisone shots and physical therapy and the pain that I was trying to get away, get out of my body through that, I lost in that 10 pounds because the inflammation was gone. And so I've lost 80 pounds since October of 2024. And I just feel amazing. and I know that my health is better, my ability to have energy. I took up Pilates, which was something I never thought I could do, but just taking better care of my health because I have 12 grandchildren I want to be around for and have energy to play with.

29:52And I know that losing that weight was going to be key to my health. Congratulations, first of all. You know I know that struggle. We have walked this walk together. I know. That's struggling. So congratulations. 80 pounds is that is that is pretty phenomenal. It's a blessing. It's a blessing. It's that is some work, girl. That is some work. So the question that I have is I've obviously seen some wonderful benefits of taking a GLP-1. My blood pressure has normalized. My cholesterol has dropped tremendously and is also getting into good numbers. What are some of the hard benefits that I can expect as a result of being on a GLP-1 and losing the weight?

30:40Yeah, first of all, congratulations. That is incredible. And, you know, GLPs have revolutionized how we are able to care for our patients. And I've seen it in my practice over the last year and a half. Patients just like you losing up to 80 pounds and really reversing their risk. And so, you know, we knew that drugs like WeGoV, right, or Ozempic have cardiovascular benefits. It has an FDA indication for that reduction of cardiovascular disease. But there was a big study that came out in October. It was 17 ,000 patients, the SELECT trial, that had known cardiovascular disease, no diabetes, who were overweight and obese.

31:20And they basically found that no matter whether you started out overweight or obese, there were cardiovascular benefits. benefits. That the weight loss - With the GLP ones? Yes. That the weight loss that you had in those first three months didn't predict the cardiovascular benefits. So if you ended up losing more later, that belly fat seemed to be a big part of risk. So losing belly fat seemed to help. However, and this is where it gets interesting, the belly fat loss only explained about a third of the cardiovascular benefits, which tells us that - Because belly fat, if you have belly fat, particularly as a woman, that's even more dangerous, right?

31:54Correct. And you're more susceptible to having a heart attack. Exactly. But the two-thirds of the benefits were not from losing belly fat. They were not from the weight loss, which is exciting because it means that the GLPs are having effects outside of the weight loss on the cardiovascular system. So the researchers and those who study this hypothesize it could be for several reasons. Number one, it's decreasing inflammation. It's lowering blood pressure and cholesterol. it's affecting the lining of the blood vessels to make them healthier. And maybe it's even changing how the fat is working in our body.

32:28So it's doing all of these things outside of just losing weight. Eventually these, I think may become cardiac drugs, not weight loss drugs. So the same way that I give my patients a statin or a blood pressure medicine, if they're not overweight or obese, but they have cardiovascular disease or they're at high risk, we might end up giving them a GLP. It has completely changed the ballgame for how we're able to care for our patients. And thank God, because we need more tools to help lower risk. Not to mention how good you feel about yourself. I mean, doesn't it just change everything the way you felt about yourself?

33:01A hundred percent. You know, I got so tired of the yo-yo. You lose the weight and then, you know, you change the way you're doing it and then the weight comes back on and it's just, oh my gosh, I'm so done with that. So, so thankful. My 80-year-old mother started taking GLPs. Your 80-year-old mother. Yes. And she struggled with her weight her entire life. You're never too late. It totally changed how happy she is, how she's able to function in her 80s. So I think, you know, at any stage of the game, this is a conversation people should be having. Should I be on a GLP? It's so helpful. Stacey, thanks for sharing with us.

33:40Thank you so much. Congratulations on your new outlook on life and the new vitality and all that comes with it. Danielle is joining us from New York. She's a patient of Dr. She's one of your patients. She is. Dr. Narula, I hear you were having the classic symptoms of menopause. Menopause came a call into you too, but felt that there was something deeper going on. Something was off. What was happening with you? Share. Dr. Narula really, really paid attention to the things that I had said to her and the way that I was feeling. And I said something to her about a particular time where I had just had dinner with my family and we were running up to go catch a show.

34:25And by the time I got to the theater, I literally could barely, I could barely walk. and that was the heaviness and I was perspiring and I was nauseous and I was dizzy. And I just kept thinking, oh my goodness, I shouldn't have eaten, I can't eat steak anymore. I don't have to go on a diet. And I just really dismissed it so heavily. But when I told that to Dr. Narula, she whipped her beautiful face around and stared at me. And she said, Danielle, please tell me exactly how you were feeling. And I really wasn't kidding because I was concerned. And she said, OK, I'm going to order this test for you.

35:09And so she did. And by the time I came home from having taken the test, I had just walked through my front door. My phone rang, and it was Dr. Narula. And she said to me, where are you? You have to come back here. She said, but it's a little too serious, I don't think. but I'd like to check something. And I'd also like for your husband to come with you. And I went in, I had the procedure done over at Northwell Lenox Hill. And when I woke up from the procedure, the surgeon said to me, do you know when your birthday is? And I said, yes, my birthday is July 26th. And I thought he was trying to like, see whether or not I was like, okay from the anesthesia.

35:55And he was so pleasant and sweet. And he said to me, well, I'd like for you to take this day, December 28th, 2018 and change your birth date because you would not have lived more than two weeks. And none of that would have happened had I not had Dr. Narula because I had been saying to my regular, you know, primary care physician, I don't feel well. I was getting embarrassed at saying it repeatedly. Yeah. When you were saying, I don't feel well, were you being dismissed or were you told it was just anxiety? Were you told, what were you told? Both. Well, a little weight and like, you know, a little tap on the shoulder.

36:34Yeah. You know, a few pounds wouldn't do too bad. Yeah. And it was just being wrapped around menopause. And yet I did have the other symptoms, you know, the, you know, spiring, um uh sleeplessness things like that but i just didn't feel well and when i said all of that to dr narula i will never forget how she looked at me and and just decided to just hear me and being heard by her and i'm told that because i have met some of her patients i went to the book signing that she recently had. Yeah, Gail was there. I managed to. Gail was there. Yeah. Yeah. And I managed. I didn't. Yeah. My entire family came.

37:19Oh, we made a big party out of this. Okay. And so it was great. It was great. And I. Oh, I see why you say you thank her for saving your life, because had she not listened, you would have continued on that circuit of going to your physician and the physician saying, you know, a few pounds wouldn't do you any harm. Yes, Oprah. Yes. It was shameful. I would feel embarrassed almost as though like I was contributing to that. Like, okay, you know, you really have to not, okay, the way - Everyone else's doubt caused you to have doubt yourself or to reassess for yourself. Well, thank you so much. What a very, and congratulations on your new birthday, December 28th.

38:06December 28th, your new birthday. It's me a lot younger. Fantastic. Thank you, Danielle. Let's talk about high blood pressure. It's known as the silent killer. I don't think everybody understands how that impacts everything else in your health, particular cardiovascular health. Tell us. It is one of the most preventable risk factors for cardiovascular disease. And people should start women, especially, having their blood pressure checked in their 20s. It is a number that you should know. A normal blood pressure, Oprah, is 120 over 80 or less. 120 to 130 is actually already considered the start or the beginnings possibly of early hypertension.

38:48Once you cross the threshold of over 130 over 80, that is considered high blood pressure. What's the most important number, the top number, the bottom number? Both are important. And I see a lot of patients who have seen doctors for years and were told, oh, your blood pressure's fine, it's fine. And then I look at their chart and it's not fine. It's been 136 over 85, which is why you should write down the number. And definitely, you know, we talk about the value of seeing a cardiologist, but the cardiologist will definitely look at your blood pressure and tell you if it's well controlled or not and what you can do about it.

39:20Right. And so the what you can do about it, there are lifestyle ways to control it, whether that's exercise, weight, low sodium diets, diets that are higher in potassium can help avoiding alcohol or medication. And sometimes it's both. But blood pressure is so important, as are all of the other risk factors. Yeah, I was resistant. I was like our earlier guest, Kayla. I was resistant to the idea of having to be on the medication because the medication means now you need medication. But I have a history of it in my family. Father had high blood pressure. Mother had high blood pressure. Every aunt, uncle, grandparent has had high blood pressure.

39:58It's a fact. And you can feel fine. That's the problem. And you can feel fine. You can feel fine, but it is damaging the blood vessels to every part of your body, your eyes, your kidneys, your heart, your brain. So it is so important to control it, even if you feel fine with things like medication. I know, because you don't even know when it's high. And listen, there's lots of stress. And I always tell my patients, I know you don't want to take medicine, but what if we get you on it and you don't even notice you're taking the medicine? How great would that be, that we get you on something that's controlling your blood pressure and you still feel the same, right?

40:28And a lot of it is trial and error, working with people to get them on something that they can really tolerate. The other thing I know you talk about in the Healing Power Resilience is that the connection to faith, to spirituality, to purpose, to hope, all of that contributes to your having a meaningful life and also beating the odds of risk of heart disease. It is. And so, you know, when I was designing the book and we were talking about what are the steps towards building resilience, a lot of them have been talked about a lot in the worlds of psychology, like flexible thinking and optimism and acceptance and all of that.

41:10But there were several that I wanted to include that I've seen and I know are important from my patient care. And those are the things that are intangible, the hope, the spirituality and faith, the purpose, the love and social connection. All of these things that are external to us or kind of bigger than us that help drive us forward and pull us forward when we are in the dark and we can't find our way out. I put purpose as the last tool in my kind of toolkit there purposefully. I call it the lighthouse, Oprah. You know, it is what calls us forward when we're stuck, when we wonder, how can I go on?

41:47What is the meaning of me being here? And all of us have some sort of purpose inside of us. Some of us never went after it because we didn't think we should. And the journey like a health scare opens your eyes to saying I should pursue that purpose. And some of us find it based on what happens to us. We become an advocate for that cause. But all of those intangible concepts, Oprah, are so powerful and meaningful. You know, love, another one that was very important for me to put in the book. I love the story from the Christopher Reeve documentary that I put in there. Yes, yes, yes. He says to his wife, Dana, like, maybe we should let me go.

42:26And she says to him, you know, I'm only going to say this once, but you're still you and I love you. And he said those words saved him. Sometimes it's just words and knowing someone's there that can save us. That power of some other human being in our life. Tell me why it was important for you at this time in your life to write this. I am such a huge believer, Oprah, in the mind-body connection, okay? I believe in the power of our abilities to overcome what happens to us in life. And I have always sort of lived my life this way. You know, I look back, the opening quote in that book is from my high school yearbook page.

43:04I am the master of my fate. I am the captain of my soul. One of my favorite, Invictus. And I had it on my yearbook page at the age of 16 as my quote. I believe we have this innate strength and power in us to overcome what happens. We're just not told that. Nobody tells us how strong we are. And I wanted to write this to help everyone and my patients and people who are struggling with medical challenges to know that no matter what happens, not only are we most, most of us innately resilient, we carry that gift with us, but it is something that we can build, we can grow, we have that power. And I want to empower people to know that they can do that no matter what happens to us.

43:41They can thrive, Oprah, in life. That is so important. Well, you are a living example of that. and I will have to say that the American Heart Association created what they call the Life's Essential Eight. The ninth should be stress. I'm pushing for that, but yes, eight. Life's Essential Eight, and it's a checklist to improve cardiovascular health. What are they? Yes. So we think about the first four. Let's talk about which are the numbers. So controlling your blood pressure, your cholesterol, your blood sugar, and your weight, your body mass index. Then we think about things that you're doing.

44:15So exercising, eating a healthy diet, avoiding smoking, and sleep. Sleep was the one that they added. It used to be seven. They added the eighth, which was sleep several years ago. Tell Gail King that. Gail, if you're listening, please. I need you to sleep more than four hours. It's so important. But yes, sleep is a time where we think our body's inactive, but actually a lot of things are happening during sleep. But if you can work on those essential eight, you will lower your risk of cardiovascular disease. 80 % of cardiovascular disease is preventable by lifestyle changes. The only things you can't control are your age and your family history.

44:51So that's so important. Again, so empowering. If we find things early, if we get on the road for prevention for women, for people, we can have a huge impact. And that's what we have to start doing is targeting this process earlier and early and early. And we have so many great screening tools, Oprah, that so many people don't know about. They think about their mammogram and their colonoscopy. We have ways to screen people to help identify those that are at higher risk. If there was a ninth, what would you want them to add? Stress. I remember sitting at a luncheon with Nancy Brown, who's the president of the AHA.

45:23She has one every year. And this was a few years ago when they added sleep. And I raised my hand and I said, I'd like to know why stress is not on that list. Because it is so important. And as we talk about, it really affects the cardiovascular system. And she put me in touch with the man who was a cardiologist in charge of the guidelines. And we had a phone conversation. And he said, you know, you're right. It is really important. We just don't have the research there to push it to the top, to get it as the ninth. But eventually, I think we will. It will be on there. It will. There's no doubt in my mind that it will be.

45:53And I hear it. When I walk in the room, the first thing I say to my patients is, how are you? And you know what they're telling me? They're not telling me their blood pressure or that they missed their medicine. They're telling me they're stressed. They're anxious. They're depressed. They're telling me everything about what's happening up here. How can we possibly help heal people if we're not addressing all of that other stuff that's going on, that's having an impact on the physical part of their bodies? Well, thank you. Thank you for your work and this really thoughtful book. The Healing Power of Resilience is available anywhere books are sold.

46:26And I also want to thank our guests, Kayla and Stacey and Danelle for sharing their heart stories with us. They actually were heart stories. and no matter your age, I hope you begin to take your heart health seriously. Thank you. Go well, everybody. Go well. And thank you to our friends at GEICO for presenting today's episode. I want to remind you again, heart disease is the number one killer of women in America. If you want to know more about what you or your loved ones can do to protect yourself and learn why resiliency is the key to building your physical and mental health, scan the QR code, buy a copy of Dr.

47:03Narula's New York Times bestselling book, The Healing Power of Resilience, a new prescription for health and well-being. Take good care of your one and only heart. Our listeners tell us that the podcast is resonating with you and is serving as a bright spot in your day. That means a lot to me. So here's the thing. I would really appreciate it if you like and subscribe to the Oprah podcast on YouTube or wherever you podcast. It's just a quick tap of the subscribe button, and that way you won't miss an episode in your queue. You don't have to pay anything. I know subscribe usually means you're paying something, but this time it means you just are notified when there's something new.

47:45There are many more to come that we're excited about, so thank you for watching and listening.

From the publisher

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The Healing Power of Resistance by Dr. Tara Narula

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Heart disease is the number one killer of women in America. One of the country’s leading cardiologists is ABC News chief medical correspondent Dr. Tara Narula who, earlier this year, released her New York Times bestselling book The Healing Power of Resilience: A New Prescription for Health and Well-Being. Oprah and Dr. Narula discuss the hidden warning signs of heart disease and how you can take better care of your cardiovascular health. Dr. Narula also explains how your connection to faith, purpose and hope can help you live a more meaningful life and beat the odds of heart disease. We also hear from a young woman in her thirties currently living with heart failure, another woman who used GLP-1s with great results towards her cardiovascular health and a patient who says Dr. Narula saved her life.


00:00:00 Welcome Dr. Narula, author of “The Healing Power of Resilience"

00:05:20 - Stats of women’s heart health 

00:11:20 - Cardiovascular disease is happening to women younger and younger

00:16:30 - Stress, women and heart health

00:24:10 - 60% of Black women live with cardiovascular disease 

00:25:50 - social determinants of health 

00:29:15 - Heart benefits of GLP-1s

00:32:20 - Menopause and heart health 

00:37:00 - High blood pressure and heart health 

00:39:20 - Faith, purpose and your health 

00:42:40 - Life’s essential 8 checklist 


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