Hack the Next Decade: Make Millions & Reverse Aging with AI (Do THIS to GET AHEAD!) | Peter Diamandis

6 Dec 2023 · 1 h 5 min

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In short

Podcast Notes: The School of Greatness - Hack the Next Decade: Make Millions & Reverse Aging with AI (Peter Diamandis)

Episode Overview

  • Host: Lewis Howes
  • Guest: Peter Diamandis, founder of XPRIZE Foundation and Singularity University, and a prominent advocate for longevity.
  • Focus: The episode explores advancements in science and technology related to healthspan, lifespan extension, and the potentials of AI in personal health management.

Key Themes and Takeaways

  1. Longevity Escape Velocity
  2. Definition: The concept where for every year you live, science extends your life by more than a year, effectively allowing indefinite life extension.
  3. Current Status: Presently, science extends life by about a quarter of a year for each year lived.
  4. Predictions: Experts like Ray Kurzweil and George Church estimate we could reach this milestone in the next 10-15 years.
  1. The Historical Context of Human Lifespan
  2. Early humans typically lived to about 30 due to harsh conditions; modern advancements have increased average lifespans to the upper 70s.
  3. Centenarians: More individuals are living to 100+, raising questions about the potential for even longer healthy lives.
  1. Health and Wellness Practices
  2. Core Health Practices:
  3. Sleep: Aim for 7-8 hours of good quality sleep.
  4. Diet: Focus on whole foods, minimize sugar intake, and consume a fiber-rich diet.
  5. Exercise: Regular physical activity is crucial for longevity.
  6. Mindset: Maintaining a positive and proactive mindset is essential for overall health.
  1. Practical Longevity Guide
  2. Free Guide: Diamandis offers a free guide on longevity practices, accessible online.
  3. Fundamentals:
  4. Emphasizes the importance of understanding bodily health and avoiding preventable health issues.
  1. Breakthrough Technologies in Health
  2. Fountain Life: A company founded by Diamandis providing advanced diagnostic services, including full-body scans and biomarkers.
  3. Therapeutics: The use of advanced therapies, including stem cells and plasma treatments, to enhance health and longevity.
  1. The XPRIZE Healthspan Initiative
  2. $101 Million Prize: Aimed at encouraging teams to develop methods for reversing aging processes in humans aged 65-80.
  3. Goals: Restore muscle strength, immune function, and cognitive abilities to levels characteristic of younger individuals.
  1. Future of Technology and Humanity
  2. AI Integration: Anticipation of AI becoming a personal health coach, integrating seamlessly with daily life for better health management.
  3. Obstacles: Addressing the societal implications of increased longevity and how to provide purpose beyond survival.

Important Quotes

  • “The best way to predict the future is to create it yourself.” - Peter Diamandis
  • “Your mindset is your greatest tool.” - Peter Diamandis

Closing Thoughts

  • The episode emphasizes optimism about the future capabilities of health and wellness technologies.
  • Listeners are encouraged to adopt proactive health practices and stay informed on advancements in longevity science.

Additional Resources

  • Free Longevity Guide: [diamandis.com/longevity](https://diamandis.com/longevity)
  • Fountain Life: [fountainlife.com](https://fountainlife.com)
  • XPRIZE Foundation: [xprize.org](https://xprize.org)

Suggested Actions for Listeners

  • Implement recommended health practices into daily routines.
  • Explore opportunities to participate in longevity and healthspan research initiatives.
  • Stay engaged with the evolving landscape of health technology and AI advancements.

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Transcript

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0:00Today, every year that you're alive, science is extending your life for about a quarter of a year. right there's going to be a point at which for every year you're alive science is extending your life for more than a year and that's called longevity escape velocity

0:19welcome to the school of greatness my name is lewis hows a former pro athlete turned lifestyle entrepreneur and each week we bring you an inspiring person or message to help you discover how to unlock your inner greatness. Thanks for spending some time with me today. Now let the class begin. Welcome back, everyone, to the School of Greatness. Very excited about our guest. We have the inspiring Peter Diamandis in the house. Good to see you, sir. Louis, a pleasure to be back. Very excited. You have recently been named by fortune as one of the world's 50 greatest leaders. Yeah, my mom paid a lot for that.

0:58Exactly. Exactly. You're also a multiple New York Times bestselling author of many books, founder of XPRIZE and Singularity and many other businesses. But what I'm most fascinated by is your commitment to helping people live longer and live healthier. In a world where it seems like there is more stress and chaos and disease and war and suffering than ever, what we need is internal harmony and peace. That'll help us live better lives today and longer. And I wanted to ask you, you've got this incredible guide that is free online right now and a book coming out that is your longevity practices and a book that is called Longevity, your practical playbook coming out.

1:47This is all your life's experience on how to sleep better, the right diets, the right exercises, the mindset, the medications, and how to not die from something stupid. And I'm curious, is it possible for us to become immortal in a sense and to extend our life, maybe not forever, but farther than we could ever imagine? I think this is the decade that we're making a real inflection in that. You know, for most of human history, you have to remember, if you go back 100 ,000 years and in the earliest days of Homo sapiens as cavemen, we would go into puberty at age 12 or 13, and we'd get pregnant, we'd have a baby, and by the time you were 27 or 28, you were a grandparent.

2:35Your baby was having a baby, right? And back then, your job was to perpetuate your species, and because we didn't have abundant food, the last thing you wanted to do was steal food from your grandchildren's mouths. So most people died by age 30. So the human body evolved really to live to age 30, and then it was a slow decline after that. And we moved to about 100 years ago. The average age was around 40. 100 years ago. 100 years ago. And then we had pasteurization and antibiotics and better sanitation and other medications. And we've moved from an average age of 40 to upper 70s now. But many people know people who are 100 years old, right?

3:24Or a centenarian or super centenarian. The question is, how old could we live? So I remember when I was in medical school, I watched a television show on long-lived sea life, that certain species of whales, bowhead whales, could live 200 years. And Greenland sharks could live like 500 years and have babies at 200 years. Oh my goodness. And so the question was, why could they live that long and why couldn't we? And I remember thinking to myself that it's either a hardware problem or a software problem. And we're going to have the ability to solve that. I think this is the decade that we are learning how to solve that.

4:02So do I think we're immortal? Probably not. Do I think we can make it to 120 consistently, 150? Yeah, I think we could. And I think that, again, the breakthroughs to enable that are coming as a result of all these exponential technologies that we spoke about last time I was on your show. you know, this is computation, sensors, networks, AI, robotics, 3D printing, synthetic biology, you know, quantum technologies. All of these things are coming together and reinventing, you know, how we understand aging and how we deal with it. So this is a magical decade. I'll say one other thing, and I'll mention why this work.

4:49There's a concept that a guy named Aubrey de Grey and Ray Kurzweil talk about called longevity escape velocity. So today, you know, science is, there's more money going into longevity research and biotech every year. I mean, it's just massively increasing. And so today, every year that you're alive, science is extending your life for about a quarter of a year, right? There's going to be a point at which for every year you're alive, science is extending your life for more than a year. and that's called longevity escape velocity. And I interviewed a few, for me, of the top scientists and thinkers in this field.

5:28I said, when are we going to see that? And their answer was pretty shocking. Ray Kurzweil believes it's within the next 10 to 12 years. George Church out of Harvard said probably the next 15 years. So if that's the case, if we can really hit longevity, escape, velocity, and that timeframe, your job and the job of everyone listening is not to die from something stupid in the interim. Right? So it's like, how do you keep yourself in the best health to intercept these breakthroughs that are coming? Because they are coming. There's no greater business. For me, AI and longevity, the two biggest business opportunities on the planet.

6:08If you could go back to your 30s or 40s, what would you have done differently then that you know now? Yes. Yes. There's a bunch of things. So the book that I have coming out or just came out is called Longevity, Your Practical Playbook. And that's amazing. I actually wrote up my longevity practices and they're available for everybody online. And I would do what I did there. Right. And they can get this on your website. They can go, yeah, diamandis.com slash longevity. And it's a free download. look. And so, you know, it breaks down to the fundamentals. It is about what you eat. It's about the exercise you get.

6:50It's about your sleep. It's about your mindset. And it's about what I call not dying for something stupid, which we can talk about, which is understanding what's going on inside your body. And I think that it's pretty damn logical. People just need to want to get there. It's what you do with your time. It's how you trade the things in your life. I don't know if you want to go with this, but happy to dive into any of that. Yeah. I mean, what would you have done if you were... All right. So first of all, okay. So when I was in medical school and grad school, I used to pride myself on how little I would sleep.

7:32It was like, I'd say, okay, five, five and a half hours, I can get by on that. And now I'm like, eight hours, it's like my objective, I'm in bed by 9, 9.30 the latest. Because my eyes pop open at 5, 5.30. You have to go to bed earlier. So I can control when I go to sleep. So getting eight hours of sleep, if the body, if evolution had allowed us to get away with less sleep, we would have evolved that way. Right? I mean, while you're sleeping, you're not hunting, you're not procreating, you're not defending yourself. It's a very vulnerable time. And so evolution would have reduced the amount of sleep.

8:14And it didn't. We need eight hours of sleep. You know, seven is a minimum, eight. and people who think they get away with less, you're fooling yourself. So sleep is the first. We can go into diet, and I spend a lot of time on that. And there's no one diet for everybody, right? I've been on a keto diet. I've been a vegan. I'm probably back to my Mediterranean diet roots. But there are some fundamentals. And one is minimizing sugar. Sugar is a poison. I mean, to be very clear, the body was never designed to take in as much sugar as we do, and it's addictive. And the sugar molecule attaches to different proteins in the body, and it's an inflammatory agent.

8:59It's a cardio-inflammatory. It's a neuro-inflammatory. It's not good. So cutting out sugar, I think, is one of the most important things you can do. the next of course is eating whole plants whole plant diet I still I'll you know eat fish and chicken whole plants for me is I attack plants by the way one little trick that I learned that I think is is is brilliant it matters the order in which you eat your food really yeah so if you got a plate in front of you eat your veggies first eat your fiber eat your protein next and then eat your carbs last. Why is that? Well, the fiber coming in actually slows your digestive track.

9:46It slows your ability and allows you to actually absorb the nutrients that come from your plants, first and foremost. It slows digestion of the protein. If you eat your white rice or your bread, I mean, you go to a French or Italian restaurant, they serve you a glass of wine and a big loaf of bread. You eat that first. Yeah, yeah. And boom, it just spikes your blood sugar. And you fill yourself with the good stuff. I mean, you have to learn the tricks and the tricks are when the, when the bread and the wine comes as, can you hold off until the main course comes? To the end. Yeah. And then if, you know, you're at a dinner party and they're putting dessert on your, on your plate, it's like, just say no before it ends up there.

10:22Cause if it's in front of you, you're battling the entire time. They're not, you're waiting 20 minutes until the food comes. Yeah. Yeah. So, I mean, the order of food, you know, your fiber, your veggies, then your protein, and then any carbs you want to take in. So, I mean, those are just some real simple basics. And then exercise, you know this. You're in amazing shape. How often do you work out? Six days a week. Yeah. Yeah. Lifting and cardio and running. Yeah. So that's super important, right? So I am trying to do the same. I'm trying to get five weight workouts in a week. Minimum of three, target's five.

11:01there's no better pro-longevity drug right now than exercise. And so if anybody's listening over 60, working out like once or twice a week, right, reduces your all-cause mortality by 50%, reducing your chance of cancer by threefold, right? And so it really is an amazing element here. and building muscle mass is one of the most important things. So for me, it's like I've been pushing to get to 10 extra pounds of muscle mass. I'm at six this year. So I've got four more to go. I feel like a straw. I'm feeling good. I'm feeling good. And it's, um, so those are the things that I wish I had thought about.

11:44So I'm 62 now, right? I'm, uh, in the, I feel like I'm in the best shape I've ever been in. And I wish I had thought about this 20 or 30 years ago. What is, how much harder is it to build muscle after 50, 60, 70? It's a lot harder, right? So your body, there's a whole process of sarcopenia, which is basically the wasting of muscle. And it's, again, as we're aging, after 30, a whole number of different elements. So your hormone levels begin to dysregulate, right? The number of stem cells in your body begin to go down. Your ability to build muscle reduces. Your thymus that generates your immune system begins to be lost and go down.

12:30So the body, because evolution never selected for these things after you reproduced, there's no pro-selective factor, it's the body begins to dysregulate and drops down. So, which brings me to what we just announced a few days ago, which I've been working on for 15 years. Wow. Which is, we've just announced a$101 million XPRIZE healthspan. So, as you know, I had started the XPRIZE Foundation 29 years ago, hard to believe. Wow. And we've launched$300 million in competitions globally. And those$300 million in prizes, one was for$10 million for spaceflight,$10 million for mapping the ocean floor,$100 million that Elon funded for pulling gigatons of carbon out of the atmosphere.

13:25And these are prizes for doing hard things. It's not for an idea. You have to actually do the thing. Solve the problem. Solve the problem. Show it done. Build the hardware. Do the science. Demonstrate it. And then you win the money. Wow. And so the largest prize to date had been this$100 million prize that Elon put up for pulling gigatonnes of carbon. And that prize is ongoing right now. It'll be won in the next couple of years. Fifteen years ago, I had a conversation with Peter Thiel and Aubrey de Grey. Could we do a longevity prize? And it was like, don't know how we'd measure it. Don't we do?

14:03So it stopped. Five years ago, the conversation picked up again. Jumbina of Sergey Young, venture capitalist, dear friend of mine, gave X Prize a half million bucks to look at this again. Then I had a conversation with a guy named George Church at Harvard Medical School. He's one of the most brilliant bio researchers, entrepreneurs on the planet. And he said, listen, you can't think of a longevity prize, but what you have to think about is a rejuvenation prize or age reversal prize, where you're asking teams not to wait and see, can a person live 30 years extra? It's going to take you 30 years to pay this thing out.

14:45But can you actually reverse a person's aging process by 10 or 20 years? How do you measure that? Yeah. So it's interesting, right? So there's no accepted biomarkers of aging, like a cholesterol level or something. But what I realized with George's help was what you really want, you don't care what a biomarker or a number on a blood report says. What you care about is at the end of this, do I have the muscle strength I had 20 years ago? Do I have the cognition I had 20 years ago? The recovery process. Yeah, the immune system I had 20 years ago. So this is an XPRIZE that we're asking teams around the world to demonstrate the ability to restore function.

15:44And we're doing this in individuals who are age 65 to 80. So any team around the world can compete. They're going to have to get a population of people age 65 to 80. and they have to give a treatment to those individuals in 12 months or less. So at the end of that 12-month process, we're then going to measure. We're going to measure that cohort of individuals before and then measure after. And did we restore the strength they had? Are we going to restore their immune function and their cognition from 20 years prior? From 20 years prior. Wow. Right? Do they have? And there's a lot of well-characterized data, and that's the goal.

16:30So fascinating. There was a study done at Harvard London School of Business in Oxford that said every year of additional healthy life is worth$38 trillion to the global economy. Really? Yeah. Think about it, because you're still productive, right? You're not spending your money on health. You know, the question is, why do people retire and get out of the business world? Either they're forced to, right, because they hit some retirement limit, or they're in pain, or they're tired, right? But if you're at 65, 75, 85, and you feel amazing, your brain is clear, you've got incredible strength, you're healthy, the last thing you want to do at the top of your game is like, you know, shut down and go crawl into a living room someplace.

17:22For people that have this desire to retire at a certain age and not work, what do you think happens to that type of individual when they stop being productive or having a purpose towards some type of work? I'll never forget, years ago, I was meeting with a billionaire here in LA who had just retired as CEO of a major company. And we had lunch, and he said something along the lines of, you know, ever since I've retired, you know, like going shopping for food and getting my hair cut in a day is the most complicated thing I do. You know? And it's like, I think people need to live a purpose-driven life.

18:09They need to have something to do. And so the question is, what are you going to do when you have that extra couple of decades of life? Maybe it's start another company. Maybe it's go and travel around the world. Maybe it's go to the moon. Maybe it's get another degree. But if you've got the energy, right, and the vitality, I think that it's great. I think people sort of conflate getting old with being in a wheelchair and drooling and being in pain. No one wants that. So, you know, let me just distinguish the term lifespan and healthspan. Lifespan is how long your ticker is going, how long your brain function is functioning.

18:57and health span is how long are you to the health to enjoy your life in every way you want your grandkids you're you know traveling around the world the quality of life quality life not the length of life and and one of the challenges is that health you know lifespan is a lot longer than health span and there's a last 20 30 years can be a degrading period what you really want is that you want your health span to continue, and the life just drop in the last week. Drop in the last week. Right. Yeah. That's what David Sinclair talks about. He said his, I think his mother was suffering for 10 years.

19:35Yeah. From, I can't remember if it was lung cancer or something, but she was declining for a decade plus. And he said it's agony watching someone you love and care about suffer. Yeah. And have, live longer, but suffer with their health. and he was like, I hope when I'm older, I just, you know, in one week, I just, you know, die. Yeah. And don't suffer. And I think everybody should want that. And I think the breakthroughs we're going to see out of this XPRIZE will help people get there. So it's, you know, it's$101 million. We expect to have hundreds of teams competing for this around the world.

20:16We're going to give away$10 million after two years. to the, we're going to give away a quarter of a million to the top 40 teams, help perpetuate them forward. And then a year and a half later, we'll give away a million dollars each to the top 10 teams. And then there's$81 million up for grabs. Yeah. It's incredible. It is our one of, we have two major sponsors and a bunch of individuals. I'm, you know, I've committed $5 million to this prize myself. We have a number of$10 million donors, a group called Hevolution, which is out of Riyadh and the US, has committed$40 million towards this prize.

20:58Wow. And then a guy named Chip Wilson, you know him as the founder of Lululemon. Okay, yeah. Chip's an amazing entrepreneur, beautiful man, who has been suffering from a muscular dystrophy, and this is a muscle function loss. And so he was the first major funder of this prize, put up a quarter of it. And then he's added a$10 million bonus for anybody who can slow or reverse his muscular distribution, his disease called FSHD. And so, you know, I think there is a lot of brilliant scientists out there. And the cost of doing biotech has plummeted. The tools that we have with AI are incredible. So, it's really about how do you make a call out to the world and say, I don't care who you are, where you went to school, what you've ever done, if you can solve this problem, right?

21:50And so, we're all suffering from aging. That is a problem, a universal problem. Yes. And I think you were telling me earlier that the kind of three main things we need to learn how to either optimize or reverse is the decline of muscle mass and strength, the immune system, and cognition. Is that right? Those are the three kind of - For this competition, those are the three we chose. And so within a year, you're going to need to sharpen the individual's mind, give them back the memory, the acuity that they had from 20 years earlier. And so someone who's 80 going back to 60 or someone who's 65 going back to 45, that's a big deal.

22:31And we know this decline that occurs as we age. For immune system, this is about your immune system is amazing, right? The two most complicated and advanced machines in the universe of the human brain and the immune system comes second. And for the immune system, your immune system is what defends you against, you know, hopefully COVID or any infectious diseases. Diseases, yeah. It also defends you against cancer. So we're always developing cancers in the body. It's just that your immune system, your innate immune system, your natural killer cells discover the cancer and zap it. So if you have a weakened immune system, you're more susceptible to cancers.

23:13And the flu and other things. And there's a concept called immunoexhaustion that's occurred. And so what we want to do is give people back their physical strength, their immune strength, and their cognitive strength. And I think those are, if you've got those, then the quality of your life has increased. So this is a seven-year competition, and we're going to follow this very carefully. And at the end of the day, my hope is by 2030, we're going to be adding at least a decade, hopefully 20 years of health to people's lives. That's incredible. Yeah. That's amazing. Now, here's the thing. There seems to be more information about health and wellness than ever before.

24:06I've had a lot of different experts on over the last couple of years. There's so many other experts sharing their content and findings online. Again, you've got this incredible guide. There's tech and tools and all these different things that can seem overwhelming for people. and it can feel like a full-time job to just manage your health and be worried about, okay, what do I need to do? And can I eat this? And when to sleep? I just turned 40 this year. Okay. Young man. And in my teens and twenties, I felt invincible, right? I felt like I can do whatever. I can train as hard as I want. I'm going to recover.

24:42I don't need to sleep. I can eat whatever. And I'm still going to be a great athlete and a specimen because I have got that testosterone or whatever. um but now i started to feel little injuries over the last couple years and i realized okay i can't just do whatever i need to be intentional about my health i've lost 30 pounds this year i've really taken on tracking and measuring things better and just optimizing and tweaking i've got a long way to go but for people who are in their 30s and 40s yeah you know i want them to get this and dive in deeper but if they're like you know what i don't have the ability to do everything but here are these five habits that I can do and take on?

25:21What could I be doing? Got it. So first and foremost, there is help that's going to be coming. You know it. We all know it. It's going to be AI, right? AI is going to ultimately become your diagnostician. We'll all have some version of Jarvis. Like a coach. A health coach, right? That is connected to your wearables and everything. You give it permission to see what you're eating, to measure your blood sugar, right? I'm wearing a continuous glucose monitor. I've got my Oura Ring, my Apple Watch. And it will ultimately be there. You set it for whatever you want, right? I'm willing to take these many pills a day.

26:01I'm willing to spend this amount of time. I'm willing to be bothered to eat the right thing or not. You know, take the stairs. Don't take the elevator. All those little things that can like. So that is coming down the line. How long is it from now? Is it three years, five years? Probably not much longer than that, where it's going to be integrated into our lives all the time, and it's going to be an incredible... There's no more advanced health diagnostician and coaching you can have at that point. Yeah, and it'll be personalized for you. Personalized for you. It'll know your genomics. Wow. It'll know when you're stressed.

26:44It'll have listened to your conversations. It'll know your schedule. It may say, listen, I have an amazing executive assistant, chief of staff, Esther, and she's like, you've got an hour Thursday morning, you should go do a workout, right? And I love her for it. But your AI may be doing that for you, right? So, those kinds of make it super easy is coming. in the interim. And I lay out in these longevity practices, diet, sleep, exercise, mindset, not dying for something stupid, meds and supplements, and you can go and ultimately decide what you want to do. Let me take them a little bit at a time.

27:31There's one important thing. So the not dying for something stupid standpoint, let's talk about that. So most people, if I ask them, is there anything going on inside your body that you need to know about? They would answer, no, I'm fine. I feel fine. I feel good. I feel good. I feel good. But the reality is we have no idea what's going on inside our bodies. You know, we know more about what's going on inside a refrigerator or inside our car than we do inside our body. And the body is incredibly good at hiding disease. A few stats. 70 % of people who have heart attacks have no symptoms before their heart attack.

28:16No shortness of breath, nothing on even a CT scan, on a typical calcium scan. and it's because historically, if you were looking for calcified plaque, that isn't what killed you. It was what's called soft plaque that isn't calcified that in the middle of the night can evulse and block a coronary artery and boom, you're dead. The cancers we die from, 70 % of those are not screened for. We screen for prostate and breast, right? And those typically don't kill you because we screen for those. But the ones like a pancreatic cancer or a glioblastoma, wherever those other cancers are that you don't screen for, those are the ones that nail you.

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29:11And one of the challenges is that we don't feel anything until it's stage three or stage four, until it's too late. the body's great at covering this up. Amazingly good. You don't have shakes from Parkinson's until 70 % of the substantia nigra neurons in the brain are gone. And so the question, if that's the case, if the body's really great of covering it up, it's like no symptoms, no symptoms, no symptoms, boom. And then it's like you go to the hospital and the doctor says, I'm sorry to tell you this, but guess what? It didn't happen that morning. It's been going on for some time. So the question becomes, how do you know?

29:51And so the way you know is by looking. So one of the companies I started with Tony Robbins three years ago was a company called Fountain Life. We have four centers right now, New York, Orlando, Naples, Dallas, we'll be opening up LA. We have a 40-center waiting list. And people come in, and we digitize you. It's a full-body MRI, brain imaging, brain blood flow. Organs, everything. Everything, right? A coronary CT with an AI looking for soft plaque in specific, right? A DEXA scan, 120 biomarkers, your full genome, your microbiome, your metabolome. It's 150 gigabytes of data. To answer two questions, one, is there anything going on inside your body you need to know about right now, first and foremost?

30:49And if there isn't, you know, knock on wood or whatever you want, what is likely to happen to you? and how do we slow it down or prevent it? Was there anything in you when you did these scans that scared you or that was worrisome? There was. So one of the things of people say, should I do this early in life? Should I wait until I'm in my 50s or 60s? So when I had my first scan, I had an enlarged aortic root where the aorta comes into the ventricle of the heart. And the question was, is that way I've always been, or is that something that is developing and enlarging? Because there's a few different diseases that have that as a symptom.

31:36And so in eight years, it hasn't changed at all. Okay. And so I'm good with that, right? And so having a baseline is really important. I had a dear friend of mine who lives in Miami. We're doing business together. I said, come through Fountain. and he went to our headquarters in Orlando. He went through. He is a very wealthy, very healthy 50-year-old guy. Comes through. Next day, gets called from our physicians. We found two aneurysms in your brain. Wow. And he just had surgery. It's all fixed and repaired, but those could have ruptured. and we've had people who have come through whose physicians said, don't waste your time.

32:24You don't need that test. You don't need this stuff and so forth. We have saved hundreds of lives. So 2 % of people who come through have a cancer they don't know about. Wow. 2%. 2.5 % of aneurysms they don't know about. 14.4%, which is a pretty big number, have either neurodegenerative disease, cardiovascular disease, or metabolic disease. They need to take care of right away. And so, again, you know, I like to say we don't know what's going on inside our body. So one of the things we do at Fountain Life is we put you through this advanced diagnostic. You go once a year. You're uploaded once a year.

33:03And then on a quarterly basis, we do some maintenance blood tests to see what's going on. The second half of Fountain Life is the most advanced therapeutics. So at the centers, we are scanning the world for what are longevity therapeutics that are safe and reasonably low risk and have efficacy. And so we've just started doing what's called therapeutic plasma exchange. And this is where you pull your blood out, you spin it, you take out the cells, you separate the cells and you pull out the plasma, which is like an oil change. and you put back pure albumin and saline. And it's like, this has been a regenerative feature in animals and it does a lot of good for humans as well.

33:55It's a six treatments a year. Wow. We have - How long have you been doing that process? I just started. We just got the equipment in, so I'm super excited about this. We have an IND with a company called Cellularity, which is one of the leading stem cell companies in the United States for giving people supplementary natural killer cells and stem cells and exosomes. So the goal is, as we start delivering these services under an FDA, what's called the Investigational New Drug, IND, is to make available these therapeutics, but to do it with a wraparound of science, which is you're uploaded, we're fully tested, then you have therapeutics and then you're fully tested again and let's measure what's actually going on inside your body and then report on the science so uh super excited about about these things you were talking about stats for a minute what is the stat that you've heard recently that scares you the most about the human population where things are going health and wellness diseases like what is the stat obesity, what is the stat that scares you the most?

35:09I think what scares me, and you know me, I'm the guy, not the glass is half full, it's overflowing. But the things that worry me are mental health and obesity.

35:28I think those two those two elements are really important for us to get a handle on. Obesity is greater than ever now, right? It is, and in different parts of the world, in different populations. And there's a very clear reason for it. It goes back to our conversation about sugar. The body was never designed to ingest these super empty calories. right? So, you know, I put blame on the food companies, on parts of the government that are not regulating around this. I mean, the garbage that kids eat for breakfast, including my kids on occasion, right? These empty calories, I mean, these are not nutritious breakfasts.

36:22this is, these are, you know, sugar covered sugar. And it's like, and when did this become, when did this become accepted as, as healthy, healthy, acceptable? Yeah. Yeah. What is the, do you know the statistics on obesity or mental health right now? I, I probably have them in, in my book. I don't have them at top of the top of mind here, but, but obesity, how much is obesity affecting healthspan and lifespan. Healthspan. Yeah. Healthspan and lifespan. Lifespan. Yeah, no, it's crazy. I mean, obesity is tied directly to cardiovascular disease. It's tied to your lack of your metabolic disease where you're basically becoming insulin insensitive.

37:16You're putting on weight. It can lead to renal disease. It can lead to even cognitive disorders.

37:27We've become a society where we're couch potatoes most of the time, and we're not incentivized to stay in good health. So it's a challenge. I mean, staying in good health takes a commitment. And the way I think about it is really, we have an amazing life coming our way. I wrote a book called Abundance, The Future is Better Than You Think now 12 years ago. I'm writing the follow-on called Age of Abundance, which I hope will come out in mid-24. And if you think about the idea that we're heading towards a world where we can uplift every man, woman, and child, give them access to all the food, water, energy, health care, education that they want, I think that's a world which is going to be a more peaceful world.

38:24Because if you have something to live for, that's an important aspect. What do you think will be the biggest problem of humanity when they have safety, food, shelter, health and wellness? What is the biggest problem that we're going to have? So the question is going to be, it may be a conversation on purpose. Right. When everything is too good and there's no problems. So do you remember that Twilight episode where there's a character who's like a gangster and he dies? and in the Twilight episode, he's in Las Vegas and all the women are there fawning over him. He goes and he's gambling. He's winning all the time.

39:09He's winning all the time. He's winning all the time. And everything's so easy. And he's like, man, heaven sucks. You know, because it's way too, it's like, you know. And then the person there goes, what makes you think you're in heaven, right? When everything is, when there's no challenge, right? We have evolved. But on the same side, I don't know if you know Sadhguru. Yeah. So brilliant. I was on stage with him in St. Petersburg years ago, and he said something I never forget. He said, technology is the means by which humanity takes a vacation from survival. so we've been surviving for a hundred thousand years surviving each other surviving the elements surviving famine disease um so but the question becomes what do we do when you can do anything and what war have we created when technology allows us to not have to survive anymore these are things we're going to figure out soon enough it's kind of like the i don't know the the generalization or the stereotype that you know rich kids get messed up you know kids of rich parents if they don't have discipline or purpose or you know something that they need to figure out things on their own they turn out to be menaces I guess of society or something right it's like spoiled yes spoiled yeah entitled as opposed to you know in service giving and hardworking.

40:39You know, it's like, how do we manage that when we have everything at our fingertips? I think the question becomes, do we up-level our challenges that we do? I mean, I would like to go start a city on the moon. Wow. That's crazy. I'd like to upload my mind into a computer. I mean, I mean, what kind of crazy things can we imagine? But you think about, you know, we're living in the year 2023, okay. But if we went back to our great-grandparents in, you know, 1900 and said, this is what life is like, you know, I think it would be almost unfathomable for them, right? Zipping around in airplanes, having Zoom conversations, you know, doing podcasts, you know.

41:32FaceTiming someone around the world. Yeah, for free. Yeah, right? And it's like, you know, what, you don't grow your food? Where's your horse to get around? And so life is going to change dramatically. It's going to change as a function of AI. I mean, dramatically within the next 10 years. Half my life is longevity. Other half my life is focused on AI, right? And so AI is going to create near infinite abundance. we have humanoid robots coming, and these robots will do our bidding for us. They'll do our labor for us. They'll do our work. They'll be accessible to us for less than the price of a car.

42:12And so what is life going to be like when we've got this? It's going to be different, for sure. What should we be most afraid of? I don't like to think of things in terms of being afraid of. abundance because I look at it as a positive thing. Yeah. But what should we be afraid of with a lot of abundance? I don't have an answer for you. Let me, you know, let's think this through together. With mental, with people who have mental illness around abundance, you know, it's like, how do we manage? Listen, we're going to, as we have abundance, we're going to have abundance of good things and abundance of bad things.

42:50I think the AI will be the tools by which we detect and it'll be a white hat, black hat, counterbalancing war. Would I rather solve the problems with the technology we're going to have in 20 years versus the technology we had 20 years ago? Sure. Will people become powerful and bored? Will we all play video games? Are we living in the middle of a video game, right? I'm still convinced this is a giant simulation. Yeah. And it means nothing. If it was, you know, it wouldn't matter. I wouldn't do anything differently. But how will we sort of engage, entertain, educate, give purpose? I mean, you know, my two 12-year-olds, they're fraternal twins.

43:50they love playing their video games, right? So they're in Roblox or they're in Minecraft or they're role-playing. And it's an engaging world, right? And someone's created that world and they're playing in it and having fun and it's creating challenges for them. I wish they were more educational as games and maybe they will be, but I can imagine a world in the future where there are engaging and challenging and fun worlds that we immerse ourselves into. We immerse ourselves into a movie right now for two hours, two and a half hours, books and so forth, entertain ourselves. I'm going to, you know, listen, a friend of mine who's the CEO of Stability AI, Imad Moustak, his company created Stable Diffusion that creates all these images, they can now create minutes of photorealistic movies, right?

44:52And next year, full length feature films. So imagine in the future where I'll say, hey, Lewis, listen, I created this virtual world of ancient Greece. If you want to go and check it out, we're exploring and talking to philosophers. Let's go for a walk with Plato and Socrates and see what it's like. And it's photorealistic and you're in your VR and you're like living there or you're on the moon or you're playing in a real life game. So I think AI and VR coming together is going to do some amazing things for us. This is an amazing period of human evolution. and we're going from one state of evolution to another.

45:44We are going to transform. Ray Kurzweil talks about the singularity, that moment in time where we're unable to predict what's coming next, where we're connecting our brains to the cloud. His prediction is that that's 10 to 12 years away, Wow. Right? Where we've got nanotechnology going in and fixing things. The challenge is that we like the world being the way it was when we went to sleep last night. We don't like challenges. We don't like these dramatic differences, but it's happening. There's no velocity switch on this change. There's no on-off switch. AI, biotech, right? At the same time, you know, two amazing women won the Nobel Prize for CRISPR to be able to go in, right?

46:39You have 3.2 billion letters from your mom, 3.2 billion letters from your dad throughout your life. That's your software. And if, unfortunately, you were born with a genetic, you know, disease, in other words, a few of those letters were off and you had sickle cell anemia, beta thalassemia, a congenital blindness, you were stuck with it. And you were fearful about having kids because you're going to pass it on to them. Now, you can expect that within our lifetime, there's going to be a cure, not a treatment, not a palliative, like take this drug, we'll take the pain away. A reversal. A single injection where you go and edit your genome, change those few letters, and you're now cured.

47:25Your genome is normal, and you don't have it anymore. Wow. I mean, this is biblical stuff. So our mind instantly goes to the negative. But I just feel like this is the most exciting time ever to be alive. And so I do think that we need to create a vision of the future that people are excited about. You know, the work I do at the XPRIZE, we've talked a little bit about this$101 million XPRIZE health span. And folks who are interested, just go to XPRIZE.org. You can learn more about it, especially if you want to compete for this prize. Go to XPRIZE.org and go for$101 million of prize money. By the way, I'll just mention the reason it's$101 million versus$100 million.

48:15Chip Wilson, my first donor, said, how big is your biggest prize? I said, well, Elon put up$100. You've got to beat that. You've got to beat that. I said, do you want to put the extra million? And he said, sure. Wow. There you go. So it's$101. One of the things we're looking at doing is creating a vision for the year 2040 of what can energy look like in 2040? What does the environment look like? What does health look like? What does education look like? And painting that hopeful, compelling, and abundant future, and then giving people a target to shoot for. And I think that's important, because we do need to know where we're going with this powerful tech.

48:56For this X Prize, again, we mentioned these kind of three categories, the muscle, immunity, and cognition. Of those three, what are you most afraid of failing? in either yourself or humans? So I think for everybody, cognition is the scary thing, right? If you lose your mind, if you have neurodegenerative disease, whether it's Alzheimer's or some form of dementia. My dad, in his later years, had dementia. I think it was secondary to his atrial fibrillation and throwing some clots. I think it was vascular dementia. but uh it's sad right uh and if you lose your memories you lose your clarity of thought you lose your your your ability to communicate focus you lose yourself and nobody wants that that's not life anymore so that's the most important thing and i think we're what are the biggest contributors to cognition loss uh well one of them is is is sugar and one of them is uh is you know, another one is stress.

50:09Um, uh, you know, another one is, uh, not understanding what your, your genetics are and not taking action. So, um, the, what are the best things? Exercise is one of the strongest ways of keeping your, your brain in great shape, uh, sleep, right minimizing sugar it's all of these very simple things and ultimately it's also putting yourself in a situation like you do every day here on this podcast it's learning something you learning right learning so everybody here listening and learning um it's it's basically exercising those neurons you have a hundred billion neurons a hundred trillion synaptic connections in your mind and you want to be stimulating and exercising those.

51:03Wow. So. What is the thing with paddle sports? I keep hearing this information around like people who play paddle or racket sports either live longer or have less memory loss or something around like ping pong and pickleball and racket ball and tennis. Like people have better quality of life. I don't know if you've heard of this. Well, I mean, I can imagine. I can imagine that. Something around the hand-eye coordination and the movement. Yeah, well, it's exercise. It's cardiovascular exercise, right? So, I mean, losing cognition, I think, is what people worry about the most. But then you lose muscle mass and you fall over.

51:41You can't push yourself up. You die that way. So what happens, and this was how my dad ended his life ultimately, was he was becoming sarcopenic. In the middle of the night, he got out of bed to go to the bathroom and fell and broke his hip. And when you break your hip or your pelvis, you're in the hospital. You can't move. You typically develop pneumonia. and then it's the same. So it's like over the age of 60 or 65 with a broken hip or pelvis, there's some ridiculously high percentage of people who die within a year. Oh, man. So injury is a problem, right? Sarcopenia, so maintaining muscle mass is critically important.

52:35So that's why I'm like, for my goals, it's muscle mass and cognition and just being in the best health. And then ultimately, your immune system is about battling infectious disease and cancer. So I think about those things. And I think about that finish line, which is not retirement, which is not death, which is that longevity escape velocity ahead of me. And those are what drive me. And I believe that these are coming. I love this. I want people to get this book. They can go on your website and get it. Yeah, diamandis.com backslash longevity. You can get the free guide online, which has got a lot of stuff, but also the book, Longevity.

53:15Yeah, on Amazon, right. And then I also, you know, one of the things, remember I said training your neural net? You're training your neural net by what you read, what you watch, what you listen to, who you hang out with. If you're reading the obituaries, right, that's not a good thing. If you're hanging out with old people in aches and pains, not a good thing. And so on the what you read, I built this AI engine called longevityinsider.org. And it scans all of the media out there. And it finds high quality articles about breakthroughs that are extending the healthy lifespan. And I get a digest of an image and a paragraph summary and a link to the article every day.

53:59And so when I read that, it's like, oh my God, that's amazing. Oh my God, that's amazing. Oh my God, that's amazing. thing. It's not what you see on CNN, right? It's the antithesis to what you see. It's this hopeful, positive future. So that's available at the same part of my website. That's your website? Yeah. Okay. It's a newsletter. Every day you get this update. Every day. Yeah. You get an update. And there's a lot going on. It's an amazing time. Yeah. What else can we do to support you today? How else can we have service? I think, tell your friends about this HealthSpan XPRIZE. We're looking for teams out there.

54:34I hope, you know, we had 6 ,000 teams enter the$100 million prize that Elon funded for gigaton carbon removal. I'm hoping to have, you know, 500 to 1 ,000 teams enter this one. There'll be startups, there'll be universities, there'll be labs, there'll be all kinds of things coming in. And, you know, I want all ideas. I like to say the day before something is really a breakthrough, it's a crazy idea. If it wasn't a crazy idea, it wouldn't be a breakthrough. So I want to find people around the world working on this. I want to change people's mindset about what's possible, capital to flow in, regulations to change.

55:18And I think it's the greatest gift we can offer humanity. Yeah, absolutely. And then, you know, if you're able, and I hope you will, go to Fountain Life and check it out. What does that consist of at Fountain Life? What do you have to do? How much time does it take? Yeah. We have four centers and a whole slew coming online, L.A. and 24, and then we're going to Europe.

55:49you sign up, you're in advance meeting over online, and then you come into one of the centers the night before and you spend the day with us. And during that day, again, we gather more information about you than you know is possible, right? So it is a full, it's 150 gigabytes of data and there's no way any human can analyze all that information. But we have a whole set of AI algorithms that are looking at your mitochondria to your cardiovascular, to your neurocognitive, everything. And our goal, again, is, is there anything going on that you need to know about? And if there is, tell you about it, because guess what?

56:36You can do something about it, right? If you catch anything early enough, including early dementia, including cardiovascular disease, including cancer, you want to know early. You don't want to wait. People say, I don't want to know. Of course you want to know. And then the other part is how do we optimize you for the decades ahead? And your job is not to live forever from this. It's to live long enough to intercept the breakthroughs that are coming. Wow. Yeah. And then there's what, like quarterly blood tests? And then we have, right, you get a, as part of this upload, you get a, it's all functional medicine.

57:17I don't know if you know, functional medicine is like the most advanced medicine. It understands the root cause at a molecular level, what's going on. It's amazing. It didn't exist when I was in medical school years ago. Right. It's amazing. So all of our docs are functional medicine docs. You get a concierge functional medicine longevity doctor as part of that. who helps you interpret that and then guides you either to fix or optimize going forward. And then you get access to a set of therapeutics. Like we'll show you this is what's just come out of Israel. This just came out of Europe. This just came out of whatever.

57:56And we make those things available at the centers for people who want it right. This is powerful stuff. I'm so excited about this. what else can we do to support you? Anything else we can... I'm just thankful to get the word out. For me, this is a life's mission, literally and figuratively.

58:18And I think, you know, this is what keeps me going. You know, it's like... It's exciting, man. It is exciting. It's amazing. People can get this PDF for free at diamandis.com. Yep. And if they want more, they can get the entire book. Yep. They can go to all the different things, fountainlife.com, mylifeforce.com as well, which can get you set up there with analyzing different things about your health. XPRIZE Foundation, XPRIZE.org. There's so many amazing things. Again, you've got about six books a year every year coming out, which are all best of. Not six, but two. Yeah, two a year. Peter, I'm so grateful for you.

58:57And every time you're on, I just really am grateful for the wisdom and the knowledge that you share openly. and I want to acknowledge you for your, really your commitment to living a great life and helping as many people do that as well. Thanks, buddy. Every business, every XPRIZE, every free thing that you give to people, you're collecting the best minds in the world and trying to solve the biggest problems. So I really acknowledge you for that. Thank you, pal. And you're welcome on here anytime to talk about the latest and greatest. So I've asked you this question before, but I'm curious if it's changed about your three truths.

59:33So I'm curious, if you could only leave three lessons behind in the world, your three truths, what would that be? So the one that's most important for me is your mindset matters. Your mindset is your greatest tool. I like to say, what made Steve Jobs, Mahatma Gandhi, Martin Luther King, Elon Musk successful? Was it their tech? Was it their friends? Was it their money? Or was it their mindset, right? It was their mindset. I really believe that. And if your mindset is that important to being a great leader, the question asks, what mindset do you have? Where did you get it? And what mindset do you need for the decade ahead?

1:00:16Wow. Right? So for me, I've been a lot of thinking and writing around mindset. The second truth is we are creating a world of abundance. that we humans are, we screw things up a lot of times, but we are incredibly good at fixing things as well and overcoming challenges. And we are creating a world of abundance. And the third one, I think the nature of the universe is love. I'm curious. I have one more question for you. Yeah, sure. if um you have twin boys you said yeah um i love dearly you love dearly yeah let's say you get to um you know see your your boys live to 60 um with all the things that happen over the next 48 years i guess um that you can predict or not predict but you know is a lot is going to happen in the world oh yeah 48 50 years based on where you see everything going in 40 to 50 years what would you say if you could share one final thing to them 50 years in the future what would you say to them about what's to come for their next oh my god 70 years beyond If you could go into the future and give a message to your sons.

1:01:49Wow. Listen, honestly, I get asked all the time to speak about the world in 50 years. I'm saying impossible. I cannot think past a decade from now, honestly. Maybe 20 years is a big stretch. 50 years from now, what is it? And we are evolving into something beyond human. We are going from evolution by natural selection to evolution by human direction. We are emerging with technology. And so I think it's unknowable. This is what Ray speaks about, the singularity, that this horizon beyond which you cannot see. So what happens when we're omniscient, omnipotent, omnipresent, you know, and we are to a large degree even now thinking about this, right?

1:02:51You can know anything, anytime, anywhere. We're living in a trillion-censor world where I can ask a question like, what's the average color of a woman's blouse or a man's jacket on Madison Avenue? and have an AI gather the data and give me the answer. We can start to know anything. So I was on stage with one of my favorite science fiction authors, Dennis Taylor. It's actually one of my son's favorite science fiction authors and mine. We've read the same books. And I asked him, it must be really hard to write science fiction these days. And he goes, it's near impossible because it's all happening.

1:03:33Wow. Yeah. Nine answer. Nine answer. Sorry. Well, maybe if it was not about the world, but just a message you'd want to give them. Oh, that it's the same message every dad wants for his kids, for them to be good humans, for them to leave the world in a better place than they had it, that they need to give their gifts to the world and do their best. And I think about there are three things I've said to my boys when they were born. I said three things I want for you. Number one, I want you to be best friends. Number two, I want you to learn to ask great questions. And number three, I want you to find your purpose in life and live that fully.

1:04:26That's beautiful. Thanks, buddy. Peter. You appreciate it, man. Thanks so much. I hope you enjoyed today's episode and it inspired you on your journey towards greatness. Make sure to check out the show notes in the description for a full rundown of today's episode with all the important links. And I want to remind you if no one has told you lately that you are loved, you are worthy, and you matter. And now it's time to go out there and do something great.

From the publisher

Recently named by Fortune as one of the “World’s 50 Greatest Leaders,” Peter Diamandis is the Founder and Executive Chairman of the XPRIZE Foundation, which leads the world in designing and operating large-scale incentive competitions. He is also the Executive Founder of Singularity University. 

As an entrepreneur, Diamandis has started over 25 companies in the areas of health tech, space, venture capital, and education. He is the Co-founder and Vice-Chairman of two public companies, Celularity and Vaxxinity. Dr. Diamandis is Co-founder & Chairman of Fountain Life, a fully-integrated platform delivering predictive, preventative, personalized, and data-driven health. Finally, he also serves as Co-founder of BOLD Capital Partners, a venture fund with half-billion dollars under management being invested in exponential technologies and longevity companies. 

Diamandis is a New York Times Bestselling author of four books: Abundance – The Future Is Better Than You Think, BOLD – How to Go Big, Create Wealth & Impact the World, and The Future is Faster Than You Think. Most recently, he co-authored the #1 best seller LIFE FORCE with Tony Robbins, which chronicles the extraordinary healthcare and biotech revolution unfolding before our eyes. 

He earned degrees in molecular genetics and aerospace engineering from MIT and holds an M.D. from Harvard Medical School. Diamandis’ favorite saying is, “The best way to predict the future is to create it yourself.”

Buy his new books, Longevity and Exponential Organizations 2.0

In this episode you will learn

  • Insights into the current state of research and technology in extending human lifespan, and what the future holds.
  • How to prepare your body and mind for achieving audacious goals, embracing the concept of 'moonshot thinking'.
  • How individuals and organizations can develop a mindset that encourages risk-taking and boundary-pushing for innovative success.
  • About the most recent breakthroughs and advancements in life extension and why they are promising.
  • The major challenges and obstacles that researchers face in the quest to extend human lifespan.

For more information go to www.lewishowes.com/1541

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Rob Dial – https://link.chtbl.com/1516-pod

Dr Joe Dispenza – https://link.chtbl.com/1494-pod

Inky Johnson – https://link.chtbl.com/1483-pod

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