In short
Longevity and “wellness” through circadian habits, targeted supplementation, and genetic methylation testing; includes travel jet-lag tactics, sleep/breathwork routines, and supplement “myth-busting.”
Guest
Gary Brecka, human biologist (degrees in biology and human biology), founder of Ultimate Human Wellness; longevity/biohacking educator with 3M+ social followers; previously worked for life insurance companies predicting mortality using large-scale death data.
Key claims
Wellness is self-directed optimization (sleep, whole-food diet, mobility, exercise) while medicine is practitioner-led. One-size-fits-all supplements and intermittent fasting can harm some people. A genetic methylation cheek-swab test identifies conversion limits (e.g., MTHFR) so people supplement for deficiency, not trends. He claims the test is “100% accurate” and that correcting methylation improves sleep depth, cognition/brain fog, mood, gut motility, and bowel regularity.
Notable examples
Travel fix—skip solid food during your normal sleeping window (fluids allowed). Morning routine—8 minutes sunlight plus long inhale/long exhale breathwork. Sleep fix—bedroom as rest-only, eye mask, avoid blue light. Creatine—used for gym gains and cognitive benefits; creatine HCl preferred for water solubility. Protein—“overrated” vs essential amino acids; non-methylated multivitamins criticized as poorly absorbed.
Written by AI. May contain mistakes. Listen to the episode to check what was said.
Chapters
Tap a time to open that second in VOJet Lag Strategies
2:26 to 4:52
Gary shares effective strategies to combat jet lag and adjust to new time zones.
“So you arrived on Sunday, is that correct?”
Defining Wellness
4:52 to 6:43
Discussion on the meaning of wellness and its control compared to medicine.
“I feel like we've jumped in there to wellness biohacking.”
The Importance of Nutritional Data
6:43 to 11:19
Gary explains the significance of understanding nutritional needs through data.
“So what it means is, you know, biology is the study of living things.”
Gary's Unique Journey
11:19 to 13:06
Gary shares his career path and experiences leading to his current focus on wellness.
“Maybe that is the next frontier of wellness.”
Mortality Prediction Insights
13:06 to 14:02
Insights from Gary's experience in predicting mortality and its relation to wellness.
“I graduated from grad school, and I went to work for large life insurance companies.”
The Importance of Data in Predicting Life
14:02 to 15:47
Learn how life insurance companies leverage unique data to predict lifespans.
“And the reason for that is that they have data that very few, if any other organization has, you know, the federal government doesn't have it.”
Empowering Change Through Knowledge
15:47 to 16:44
Discover how understanding modifiable risk factors can extend your lifespan.
“And so that's kind of why I'm sitting here today.”
Creatine: Beyond Muscle Gains
16:44 to 17:33
Explore the varied benefits of creatine, including cognitive enhancements.
“And so I think that that message that we are a lot more empowered than we think we might think we are.”
Creatine's Role in Mood and Sleep
17:33 to 19:10
Understand how creatine affects mood regulation and sleep quality.
“And so what the body does is it takes all of these raw materials and as it starts to process them, the waste from certain processing goes into feed the next transaction.”
Genetics and Gut Health
19:10 to 21:54
Learn how genetic mutations can impact gut health and overall well-being.
“People that have a hard time falling asleep because their mind is awake, not because their body's not tired.”
Show all 24 chapters
The Gut-Brain Connection
21:54 to 24:14
Uncover the links between gut health and mental health, including serotonin production.
“So in other words, you can't take that crude oil and convert it to gasoline.”
Restoring Neurotransmitter Production
24:14 to 26:54
Find out how to enhance neurotransmitter levels for improved mental health.
“we turn the serotonin factory back on for example well we make serotonin critical neurotransmitter from an amino acid called tryptophan.”
Establishing a Healthy Daily Routine
26:54 to 28:00
Learn practical tips for setting a daily routine that supports health.
“when you give it the raw material it needs to do its job.”
Morning Routine for a Better Day
28:00 to 33:04
Learn how a simple morning routine can improve your circadian clock and overall health.
“Yeah, what I might add to that is think about taking eight minutes and inserting a common practice that you do every single day.”
Consistent Sleep and Travel Tips
33:04 to 35:01
Discover strategies to maintain a consistent sleep routine even while traveling.
“Now, if you're going to go to Dubai and you're going to spend a month there, just go through the brain damage of getting on the time zone.”
Personalized Wellness Strategies
35:01 to 37:17
Find out why individualized wellness approaches are essential and how to start.
“what would be one thing that would be most effective to start with and maybe one thing most effective to avoid?”
Wellness Trends and Information Sources
37:17 to 39:51
Explore the rising interest in wellness and how to find reliable information.
“But now that wellness has become the fastest growing area of human interest worldwide, people are like, what's the next step?”
Quick Fire Wellness Questions
40:04 to 42:00
Get concise answers to popular wellness questions and myths.
“Let's finish with some quick fire this or that questions.”
The Role of Amino Acids and Peptides
42:00 to 43:10
Learn about the importance of amino acids and peptides in the body.
“The reason why we have a protein equivalent, you probably heard one gram of protein for every kilogram of body weight, that's a very common one, is to get to the amino acids.”
Walking and Exercise Preferences
43:10 to 44:27
Discover the benefits of different walking styles and workout timings.
“So fast walk, slow walk, intentional walk, relaxed walk.”
Nutrition Strategies: Intermittent Fasting vs. Meals
44:27 to 45:42
Explore the pros and cons of intermittent fasting and meal frequency.
“to knock it out in the morning, but that's not true.”
Wearables and Health Monitoring
45:42 to 46:59
Examine the impact of wearables on health data and stress management.
“Wearables, essential or anxiety inducing?”
Supplements and Health Myths
46:59 to 48:26
Identify common misconceptions about supplements and their effectiveness.
“And you can choose to ignore it if you want to.”
Closing Thoughts on Longevity
48:26 to 49:15
Reflect on the key takeaways regarding health and longevity.
“If it went into the tissues, it wouldn't show up in the urine.”
Transcript
Automatic transcript. May contain errors.0:02That's the sound of zero sugar, 200 milligrams of caffeine, and the power to burn body fat. Storm, energy for life. Storm Energy Blend helps boost metabolism, which in combination with exercise and a healthy diet helps burn fat. This product alone does not produce weight loss. Individual results may vary.
0:15Gary Brecka:So good, so good, so good. New summer arrivals are at Nordstrom Rack stores now. Get ready to save big with up to 60 % off brands like Rag & Bone, Levi's, Adidas, and Free People. Join the Nordy Club to unlock exclusive discounts, shop new arrivals first and more. Plus, buy online and pick up at your favorite rack store for free. Great brands, great prices. That's why you rack. Welcome to this week's SR Man episode where we're joined by Gary Brecker. In this week's episode, he's explaining how one simple DNA test can transform your wellness journey. I really, truly believe that every human being, once in their lifetime, should do a genetic methylation test.
0:59Gary Brecka:So they stop supplementing for the sake of supplementing. They start supplementing for deficiency. This alone will eliminate so much stress and noise from your body. General myth-busting around supplements. Protein, I think, is overrated. I'm a fan of creatine, not just because of its capacity to improve gains that we make in the gym. but for its cognitive benefits. And one quick hack that'll upgrade your daily routine. Long, slow, obnoxious inhale through your nose. Pause and out through a straw. Thanks so much for joining us. It's a good one.
1:48Welcome back to the SL Man podcast with me, Harvey James. Today I'm joined by Gary Brecker, a renowned human biologist, founder of the Ultimate Human Wellness. He's a leader in the fields of longevity and biohacking, and someone who's managed to captivate an audience of over 3 million on social media with his insights and answers on those topics and more. Today, we're going to talk all things wellness, from training to supplementing, how to live longer, how to live better. We'll be answering your questions on those topics and beyond. So welcome, Gary. How are you? I'm amazing, man. Good. So you arrived on Sunday, is that correct?
2:28Gary Brecka:I arrived on Sunday for the health event. Went Monday to Cannes, France, came back last night, and here we are. You're not wellnessed out yet. I'm not wellnessed out. My voice has given up on me. I'm a little hoarse. Yeah. Um, I, uh, the day before that I spoke for five hours in the Utah desert. So, and when I went home that night, I woke up the next morning, I had no voice. So I've never lost my voice before. So I don't know much about the Utah desert, but it doesn't sound like very dry. Not, not great. Not great. And so we were talking a bit before about jet lag and some of your, your ways to combat it?
3:05Do you want to just explain that? Yeah, sure.
3:06Gary Brecka:I mean, I will tell you the one that I never hear anyone talk about, and it is arguably the single best thing you can do when you're traveling to adjust to a new time zone, and that is to not eat during your normal sleeping window. I live on the East Coast of the US in Miami. So I go to bed at 10 p.m. I wake up at six o 'clock in the morning. So between 10 p.m. and 6 a.m., my body's used to sleeping. If I feed myself during that normal sleeping window, it will throw my circadian clock off worse than anything. So if I go to the UK like I am right now, it's five hours ahead, which means that 6 o 'clock in the morning is 11 o 'clock in the morning here.
3:46Gary Brecka:I just won't eat solid food before 11 a.m. That's it. Is that difficult? No, it's not difficult at all. You get up at 7, 8 o 'clock in the morning here, you don't put solid food in your body until 11 a.m. It's very easy. you can have all the fluids you want. You can have coffee, you can have tea, you can have water. It doesn't interrupt my workouts. And that way you're keeping your digestive clock on the same time. And there's so many different clocks inside of our body that run our circadian rhythm. We're very circadian creatures. Our bodies love habit. And there's a master clock in the brain.
4:21Gary Brecka:It's called the suprachiasmatic nucleus. And what this does is it runs all kinds of different systems in the body, your cortisol cycle, your melatonin cycle. For women, it runs their hormonal cycle, their menstrual cycle. And when you throw it off through travel, you want to keep as many of those clocks on the same schedule as possible. So one of the things we have control over is the timing of food. So if you eat at the same time, regardless of where you are in the world, major difference in your ability to adjust to a time zone. I feel like we've jumped in there to wellness biohacking. Yeah, we just went in.
4:59We even hit female hormones.
5:00Gary Brecka:Yeah. So yeah, we're in it now. We're in it there. That was great. No, let's talk a little bit about wellness and what that is, because it's a word that's risen in popularity, I'd say in the last five to 10 years with the rise of kind of influences, but also our understanding about science and how we can optimize our bodies a little bit more. so let's get your kind of definition of what that word means well i think that medicine is something that we outsource and wellness is something we have control over so your wellness journey is the journey to being the optimal person the optimal state of you but you're in control so what are the things that i can do to not just add years to my life but life to my years what can i do to improve my cognitive function, my waking energy, my sleep, my focus, my response to exercise.
5:53Gary Brecka:And these are all a part of a wellness journey. So things like targeting your sleep, which is our human superpower, and probably the most bullied thing in our schedule. You know, we really bully sleep around in our schedule, right? I mean, when you ask most people, what do you do to go to sleep? They go, what do you mean, Gary? I just lay down in bed. And I say, well, what time do you go to bed. Well, whenever I'm done getting my work done. So, you know, sleep is truly our human superpower. Eating a whole food diet, a diet absent processed foods, making mobility non-negotiable, making exercise non-negotiable.
6:28Gary Brecka:These are things that are in our control and they should be a part of our wellness journey. So I really see wellness as things people have a personal possession of, whereas medicine is something that really should be done done by you know a licensed practitioner somebody who's trained to actually put pharmaceuticals or chemicals or synthetics into your body you call yourself a human biologist what does that mean and how did your career path get you here yeah yeah so i don't just call myself a human biologist that's what my degree is in so fine um my my undergraduate degree was in biology yeah um and then i went to grad school and got a second degree in human biology.
7:07Gary Brecka:So what it means is, you know, biology is the study of living things. Human biology is the study of human beings. And so I have a fascination with the human body and its form, its function. How can we improve it? I mean, how can we harness the God-given power of our immune system? What can we do that's within our own control to change the entire trajectory of our life. And there's so much that we can do that is so empowering that if people would understand how human beings operate, for example, if you want to see magic happen in human beings, you give their body the raw material it needs to do its job.
7:51Gary Brecka:And so very often we're deficient in raw materials. You know, we believe this in plant physiology. So if you had a leaf, let's say, rotting in a palm tree, and you called a true arborist, like a true botanist, out to look at that leaf, they wouldn't even touch the leaf. They would core test the soil. And they would say, you know what? There's no nitrogen in the soil. They would add nitrogen to the soil and the leaf would heal. Human beings, I promise you, are no different. When you deprive the human body of certain raw materials, vitamins, minerals, amino acids, nutrients, you get the expression of dysfunction, expression of disease.
8:29The ultimate human wellness. How did that brand come about and what were your goals when starting?
8:34Gary Brecka:Well, the ultimate human wellness was meant to be the cleanest, most bioavailable supplements that science had to offer. And one of the reasons why I believe so much in targeted supplementation, meaning not supplementing for the sake of supplementing, but supplementing for deficiency. And this is where the magic happens. Most people start their supplement journey by either catching something on TikTok or Instagram or an influencer or their neighbor or their coworker or their boyfriend or girlfriend. And this is the reason why one size doesn't fit all. I'm a true believer in getting data. I think that data is so important to our wellness journey.
9:18Gary Brecka:So I'm really proud of being able to bring what's called a genetic methylation test. to the UK. It's done right here in a UK lab. And it's a cheek swab. You put a cheek swab in your mouth, you send it off to the lab, and the results that come back tell your body exactly what raw material your body can turn into the usable form and what it can't. You see, what most people don't realize about supplements is that, number one, one size doesn't fit all. But number two, there is not a single compound known to mankind, not one, that we put into the human body that is used in the format that we put it in, with no exception.
10:02Gary Brecka:There's no vitamin, no mineral, no amino acid, no protein, no carbohydrate that we use in the form that we put it in. Without exception, everything that enters our body gets converted into the usable form. So imagine that we pull crude oil out of the ground. You can't put crude oil into your gas tank because the car doesn't understand that fuel source. But if you take crude oil and you refine it to gasoline, now the car can run. Human beings are no different. So when you do a genetic methylation test, it tells you, what can I convert from crude oil to gasoline? What can I convert from the form that entered my body to the form that my body can use.
10:48Gary Brecka:And once you know that, you no longer guess about what you need to supplement with. And this is why some people have like miracle results with certain supplements. And some people go, I started taking ashwagandha, St. John's work, CoQ10, NAD, NMN, and I felt nothing. It's because your body wasn't deficient in that. Your body could convert those raw materials. But once you find out what you can't convert, And you put that back into the body. And that's when magic happens. That's fascinating. Yeah. Maybe that is the next frontier of wellness. Is it more personalized? Yes. The next frontier of wellness is personalized wellness, data-driven wellness, individualized wellness.
11:31Gary Brecka:For so long, we've had this one size fits all, men's multivitamin, women's multivitamin, women over 40 multivitamin, kids vitamin. And they all have relatively the same ingredients. uh but the question is what does your body need you know a good mechanic is somebody that fixes your car a great mechanic is somebody that keeps your car from breaking down and i think there's a material difference and people that are on a wellness journey they don't want to break down right they they don't necessarily want to have to rely on a system that they outsource to make choices for their health health journey and and the way to avoid that is to make sure that your body has the raw material it needs to do its job i suppose that will come into medicine as well and hopefully in the future where they've got personalized drug kind of um use as well rather than just being on the wellness i think so too i think you see a lot of precision coming into uh mainstream medicine now you know again we we very often will do genetic testing to determine what drugs certain patients will respond to.
12:37Gary Brecka:Not everyone responds to any inflammatories or pain medication or psychiatric medication the same way. So what's true in medicine is also true in wellness. The same is true with supplements as you have with chemicals and synthetics and pharmaceuticals. And so getting that piece of data is the missing link between getting so much more out of your wellness journey and just feeling like you're supplementing for the sake of supplementing what's your personal story obviously you you studied human biology was it at that point that you decided i want to kind of not experiment with myself but get into it for my own health reasons rather than just intellectually being interested in it You know, I had kind of a unique journey.
13:26Gary Brecka:I graduated from grad school, and I went to work for large life insurance companies. And the team that I was on was charged with predicting mortality to the month. So not just putting you on an actuarial curve. It's creepy. But telling the insurance company how many more months you had left on earth. and i get a lot of flack for saying that but the truth is it's some of the most accurate science in the world because life insurance companies have data that no other financial services enterprise um has and it's in their interest to get it right it's in their interest to get it right and if you want to know how good they are at predicting death just look at what happened during the 2008 2009 financial services crisis you had 364 banks fail not a single life insurance company failed they are some of the most solvent institutions in the world.
14:21Gary Brecka:And the reason for that is that they have data that very few, if any other organization has, you know, the federal government doesn't have it. Our CDC and FDA don't have it. Collegiate universities don't have it. They know the day, the date, the time, the location, and the cause of death for 371 million lives. And so you take that data and you draw it back into the record and you say, what are some of the blood biomarkers? what are some of the patterns that lead to early demise? And I can tell you that if I was to boil that entire 22-year career down to just a few sentences, it would be that the reason why the vast majority of humanity is not living healthier, happier, longer, more fulfilling lives are what we called modifiable risk factors.
15:15Gary Brecka:These were dietary and lifestyle changes that if people would have implemented, would have added in our model on average seven years to their lifespan and their healthspan. And people just didn't feel that empowered to change their journey. And after doing that for so long, I finally said to myself, like, what am I doing? You know, Am I going to spend the rest of my life predicting death? Or am I going to take this information and get it to the masses and help people live healthier, happier, longer, more fulfilling lives? And so that's kind of why I'm sitting here today. That's amazing. Did you feel like you were kind of like the person to communicate that?
15:59Gary Brecka:Well, you know, I think God blessed me with, you know, the talent of being able to take the ultra complicated and make it simple. because it's not about trying to impress people with how smart you are. It's about giving people enough education so that they're inspired to make a change. Because if you don't affect somebody's habits, nothing else matters. We're not a collection of our goals. We're not a collection of our priorities or our desires. We are a consequence of our daily habits. The micro daily habits that we do every single day, that's what you are a consequence of. You can look at somebody and tell if they're in the gym on a regular basis.
16:39Gary Brecka:You can look at somebody and tell, um, you know, what kind of care they take of themselves. And so I think that that message that we are a lot more empowered than we think we might think we are. Let's get into a bit more of the minutiae of kind of some supplements and substances that are quite popular at the moment. So there's a lot of talk around creatine. yes um personally i've used it and i found it really effective as well but let's sort of try and get to the bottom of some of these myths around it sure is it just for building muscle or well you know i am an enormous fan of creatine there's creatine monohydrate and there's creatine hydrochloride hcl i'm a huge fan of creatine hcl because it's 41 more water soluble than monohydrate even though there's more data on monohydrate there's still very solid data on hcl and for women especially that are concerned about bloating men too men don't want to bloat either um hcl is much more water soluble but i'm a fan of creatine not just because of its capacity to improve gains that we make in the gym but for its cognitive benefits for its ability to restore natural capability to the body to um methylate and what i mean by that is the human body is fascinating there's a saying one man's trash is another man's treasure this is very true in how the body processes nutrients we take certain amino acids into the body and then that amino acid is broken down into other amino acids some build muscle muscle some build bone some build connective tissue some build natural killer cells some build collagen elastin and fibrin.
18:27Gary Brecka:And so what the body does is it takes all of these raw materials and as it starts to process them, the waste from certain processing goes into feed the next transaction. Creatine is one of those that is produced by the body. We make creatine endogenously inside of our body. When we're not producing enough, the body goes to other resources, mainly something called SAM-E, S-A-M, lowercase e. And SAMe is the primary methyl donor in the body. It's very much involved in our mood, in our emotion. It's very much involved in our sleep-wake cycle. People that have a hard time falling asleep because their mind is awake, not because their body's not tired.
19:18Gary Brecka:SAMe is the most necessary methyl donor. If you're deficient in creatine, the body will steal it from SAMe. The same way that if you're deficient in minerals, your body will steal it from the bones. If you're deficient in amino acids, your body will rob it from lean muscle. So in order to stop your body from using one resource that it's deficient in and stealing it from another resource, creatine is one of those things that we can put into the body and has such a myriad of benefits. I mean, I say that if you're a woman over 40, you have to be taking creatine um men as well um you know men mainly take it for uh gains in the gym and they're not so enticed by the cognitive benefits but they get those too but i'm a huge huge fan of creatine yeah i i came onto it after suffering quite a long bout of insomnia and kind hearing reports online about that kind of macro dosing or doing a little slightly more than what's recommended on a day that you haven't slept very well.
20:28Gary Brecka:Up to 20 milligrams. Yeah. It can have quite a powerful effect. Not just a powerful effect, but it can mitigate the effects of not sleeping. Yeah. And there's nothing else that can do that. Yeah. It does feel quite magical in that sense. Yeah. How can it restore this kind of thing that otherwise you would feel like you've been hit by truck. Yeah, exactly. So if you have periods of sleep deprivation, high stress, you know, you can go up to four times the daily dose of creatine and mitigate the effects of having not slept. That's very, very true. There's a lot of science around that. Could your test detect whether you're deficient in creatine?
21:06Gary Brecka:Well, what it will do is detect whether or not you're deficient in methylating creatine and methylating something called SAMe. So you'll know exactly what to supplement with. So let's say you do this cheek swab and you find out that you have the MTHFR gene mutation, which is the most common gene mutation in the world. About 46 % of the population has this gene mutation. When you have this gene mutation, you have an inability to convert folate and folic acid into the usable form. Now that doesn't sound like a big deal until you realize that folic acid is the most prevalent nutrient in the human diet.
21:49Gary Brecka:When you can't convert that nutrient into the form the body can use. So in other words, you can't take that crude oil and convert it to gasoline. What are the consequences of that? Well, one of the primary consequences is poor gut motility. And gut motility has to do with the pace of the gut. There's listeners listening to this podcast right now that are struggling with gas, bloating, diarrhea, constipation, irritability, and cramping. And they've searched for years in their diet. They've done every food allergy, food sensitivity test. They've done gut microbiome testing and nothing seems to work because the most overlooked thing, in my opinion, in all of bariatric medicine is the pace of the gut.
22:34Gary Brecka:Your gut is like a 30-foot-long conveyor belt, and we put contents on it at one end when they exit the stomach. 30 feet later, they exit the rectum, and the pace of that conveyor belt is critical to its processing. So if you went into any factory in the world that worked on a conveyor belt system and you just walked into the factory and doubled the speed of the conveyor belt, the whole factory would break down. not because there's anything wrong with the conveyor belt there's nothing wrong with the contents on the conveyor belt what you've done is you've changed the speed too slow constipation too fast diarrhea pausing gas bloating cramping so if we can restore the motility which you can um by supplementing with something called methylfolate which that genetic test will tell you um then you restore the natural pace of the gut and people go wow i didn't have a food allergy or food sensitivity.
23:27Gary Brecka:It wasn't dairy or wheat or gluten or blueberries or bananas. Like my test said, it was just the pace of the gut. And then if you look at what else happens when you change the pace of the gut, well, we make 90 % of the neurotransmitters that form mood and emotion. 90 % of the serotonin in your body is in your gut. So if you don't have it there, you can't have it in your brain. Serotonin travels up the vagus nerve. It populates the brain. It creates mood. It creates an emotion. and so you have a mood disorder or an emotional disorder and really what you don't have is a mood or emotional disorder which you have is a deficiency from serotonin production in the gut so very often when we go back into the soil and we say how do we restore optimal function how do we turn the serotonin factory back on for example well we make serotonin critical neurotransmitter from an amino acid called tryptophan.
24:26Gary Brecka:And we use certain B vitamins and we use certain methyl donors to take that tryptophan and turn it into serotonin. Well, if that cycle's broken, it can be fixed very often with simple nutrients. Same thing happens with dopamine. When dopamine is low, which is the main driver of behavior, very often we refer to this as depression. Low serotonin referred to as depression, low dopamine becoming a driver of addiction. You know, someone that is a true addict did not wake up one day and say, I want to get really smashed. I want to get really banged up. What do you say here? Really pissed. Pissed. Pissed.
25:07Gary Brecka:I love the Brits, dude. You guys got cool names for everything, like schemes and pissed. We're trying to hide the fact of what it is to make it sound cooler. Yeah, it does sound a little cooler. Yeah, we say, you know, we say drunk, banged up. But I like pissed. I'm going to bring that one back with me. So most addicts didn't wake up one day and say, I want to get really banged up. They woke up one day and said, I want to feel normal. It was the search for normalcy where they developed an addiction. And that normalcy was the drive to get dopamine back because that's the main driver of behavior.
25:42Gary Brecka:What if you could turn the dopamine factory back on with simple nutrients? What if you could turn the serotonin factory back on with simple nutrients? What if you could quiet the mind so that when you laid down to go to sleep at night and your mind woke up, which is called rumination, and you laid there body tired but mind awake, what if you could just calm the mind? Because most people think about sleep as being tired. That's not true. Sleep is not about being exhausted. Going to sleep is about your body feeling safe to shut off. And you don't do this by tranquilizing yourself. You do this by quieting the mind.
26:20Gary Brecka:And that's why one of the things that people commonly report after doing that genetic methylation test is, oh my God, Gary, my sleep improved immediately. I stopped ruminating at night. I didn't notice my husband or wife even got out of bed and came back to bed at night. I sleep through the night. I noticed that I'm not sleeping longer, but I'm sleeping deeper. For the first time, I'm waking up refreshed. I feel clear and cognizant in the morning. I just thought brain fog was a consequence of aging, which it's not. or it's a consequence of missing raw material. And it's just so fascinating to see how extraordinary the human body can function when you give it the raw material it needs to do its job.
26:58The daily routine, because you were talking earlier about the body as this kind of complex clock system. Yes. So the daily routine is an important part of setting up those systems. No questions. I'm going to share mine. Okay. And you can see how awful it is. Just give your thoughts because the daily routine as well is something that probably changes a lot for people as some things work and don't. And as your life changes, I've just had a newborn son. Good for you. Congratulations. Change that. But so my daily routine, I'm waking up at seven and then immediately looking at my phone. I'm then probably checking my aura ring score.
27:40or probably potentially going on emails, depending on how busy I am. Then I'm going to iron my clothes, and then I'm making a coffee. But ideally before that, I'm having yogurt, fruit.
Read the full transcript
27:53Gary Brecka:Not bad. And a bit of granola. Okay. And then the coffee comes in, and then we start the day. And that's, you know. That's not a terrible morning routine. It feels quite normal, actually. Yeah, what I might add to that is think about taking eight minutes and inserting a common practice that you do every single day. And you don't have to do it at the same time. You have to do it within 30 minutes of waking. And all I would ask you to do is get outside in natural sunlight, even if it's overcast, because I know it gets gloomy here in the UK. Even if it's overcast, there are certain wavelengths of light that come right through the crowds.
28:36Gary Brecka:Natural sunlight will do more to reset your circadian clock and set you up for a good night's sleep that night than just about anything else that you do. And before you got on your phone, if you would just do a simple round of breath work, three rounds of five breaths, that's it. Eyes open, in natural sunlight, long, slow, obnoxious inhale through your nose. pause and out through a straw and then obnoxious breath in do five breaths hold your breath as long as you can five more breaths hold as long as you can five more breaths hold as long as you can eyes wide open exhale back inside that's it just that simple change what will happen is you remember the old experiment called Pavlov's dog.
29:31Gary Brecka:It's a famous experiment where they rang the bell, fed the dog, rang the bell, fed the dog. And eventually what would happen is they'd ring the bell and the dog would start to salivate. And the reason for that is the anticipation of, it's a cue of what's to come. So when you do the same thing every morning, breathwork, sunlight, breathwork, sunlight, then your body starts to know when we do breathwork and get sunlight, it's time to wake up. You see that it helps to raise cortisol, which is a waking hormone. It helps to suppress melatonin, which is a sleeping hormone naturally. And it helps to put you back on a good circadian clock.
30:07Gary Brecka:I say the same thing about going to bed at night. You know, the one thing that you can do that won't cost you a thing is set up your bedroom like an area of respite, a place that you go to relax because what the human brain does in an effort to protect you is it frames things. So for example, let's say you were in your kitchen and it was two o 'clock in the afternoon and you left your keys in your car. And you'd have no problem. You walk out to your car, you go out in the street, pop open the door, you get your keys, you come back in. Now it's one o 'clock in the morning. It's pitch black. You left your keys in your car.
30:46Gary Brecka:You might think twice about actually going out to get them because it's nighttime, cars on the street, you can't see. so there's this perception of fear we do the same thing with how our brain frames our office how we frame the doctor's office there's something called white coat syndrome where just walking into the doctor's office your blood pressure can rise nothing happened to you you're just going into a doctor's office the same thing happens in your sleep environment so what do you do do you have intense conversations with your spouse while you're in bed um do you work on your laptop when you're in bed is that a place you go to be efficient is that a place you go to negotiate with your spouse?
31:24Gary Brecka:Is that a place you go to work? Is that a place you go to get entertained? Because if you do, that's the association your brain will have with your sleeping environment. If you just took a step back and said, I'm going to set my, just my bedroom, or at least my bed up as a place of rest and relaxation. I'm going to invest in a good mattress. I'm going to invest in good sheets and pillows. I'm going to have dim lighting in there. I'm going to surgically remove all the light. It's going to be a nice, cool environment when I go to bed. I'm not going to work in bed. I'm not going to have intense conversations with my spouse in bed.
31:57Gary Brecka:I'm not going to scroll on blue light while I'm in bed. This is where I go to shut down. You would be amazed at how that framing changes in your mind. So even as you just walk into your own bedroom, your body starts to power down. And then if you got in bed and if there's any light coming into your room, invest in a$10,$12 cotton eye mask. if you need to be entertained while you're in bed, listen to a podcast, but put the phone a few feet from your head on your nightstand and don't stare into a blue screen. And then learn to do a cycle of breath work that they call natural Xanax. And this is long, slow inhale through the nose, a long pause, and exhale through a really tiny straw, a really prolonged exhale,
32:49Gary Brecka:I promise you, if you do those things, you will not make it to 10 breaths. No question. And it will help you. And if you did that every night, and what I just explained in the morning, which will cost you nothing, it's totally portable. Then you started your coffee, your supplements, went to the gym, and had your first meal. Game changer for your circadian clock. how do you deal with disruptions to that because you're a busy guy you've got a schedule that i imagine changes like like this week yeah how do you kind of deal with the you know knowing that you haven't really done the your routine and kind of do you try and do little bits of it things that are achievable how does it not you you never change the bookends okay you never change the routine to go to sleep you never change the routine to wake up and you never change the digestive clock.
33:43Gary Brecka:Now, if you're going to go to Dubai and you're going to spend a month there, just go through the brain damage of getting on the time zone. But if you travel a lot like I do, I do the exact same routine to go to bed. I do the exact same routine to get up. So this morning, luckily I have like big windows in the, I'm staying at Six Senses here, beautiful hotel by the way. And I'm able to get the windows open, get natural sunlight, do my breath work in the morning. I do the same breath work when I go to bed at night. I have an eye mask that I travel with. I don't have alcohol. Well, I don't drink.
34:15Gary Brecka:But for those of you that do drink, stop alcohol three hours before bedtime. Don't eat within two hours of going to bed. And keep your room cold and dark. And if you can't get it dark, put an eye mask on. Do the breathwork technique that I just described. It's portable anywhere in the world. And it is amazing. So I can fall asleep at different times because I have the same routine to fall asleep. I can wake up at different times because I have the same routine to wake up. and it's really, really helpful. It does kind of feel like you're tricking your body, but making those associations. Yeah. I suppose you're manipulating a bit in a positive way.
34:52Yeah, that association. Set off the cascade of positive kind of reactions. And so if someone's getting into wellness and discovering what it's all about, what would be one thing that would be most effective to start with and maybe one thing most effective to avoid?
35:09Gary Brecka:well avoid the one size fits all right um we know now that just about everything is individualized you know you see a lot of women for example that will start uh intermittent fasting with their boyfriend or their husband and husband's doing amazing uh he's losing weight feels great sleeping like a bear he's putting on muscles got all the energy in the world and the wife is eating in a smaller and smaller and smaller feeding window and she's gaining weight because she's retaining water because she's thrown off her hormone cycle. Some of the worst endocrine disasters I have ever had to manage have been young menstruating women that eat in too narrow of a feeding window.
35:50Gary Brecka:So intermittent fasting is one of those things that's not for everybody. Supplementation is the same way. What you want to do is get data. I really, truly believe that every human being once in their lifetime should do a genetic methylation test. So they stop supplementing for the sake of supplementing. They start supplementing for deficiency. This alone will eliminate so much stress and noise from your body. You do the test once in your life. Once you get that data, you know, I need methylfolate. I need SAMe. I need trimethylglycine. You should, when you get that right, feel the difference. Waking energy, cognitive function, short-term recall, absence of brain fog, regular bowel movements, which is one of the greatest predictors of longevity, deeper sleep, not longer sleep, deeper sleep, waking up refreshed, having a positive response to exercise.
36:45All of those things are well within our grasp
36:49Gary Brecka:if you get targeted supplementation right. How accurate is it? It is 100 % accurate. Oh yeah, the genes you're born with are the genes you die with. The lab that we use here in the UK is an excellent genetics lab. It took a long, long time to set this up and to get all the supplements through the UK health authorities. They're not easy. But which is a good thing for, you know, for residents in the UK. You guys have really gotten food significantly better than most countries. But now that wellness has become the fastest growing area of human interest worldwide, people are like, what's the next step?
37:27Gary Brecka:And I think the next step is testing. Let's talk about the brand, The Ultimate Human Wellness. So you've got a podcast, protocols and products. If someone completely new to the brand, where should they start on that journey? Well, a great place to start is my social media channel at Gary Brecca. I do nothing but teach on that channel. The sole reason that that media channel exists is to give without the expectation of receipt. So a lot of very, very, very practical, science-based, evidence-backed tips to help you sift through the noise. Like, what is the best way to cold plunge? Should I sauna then cold plunge?
38:04Gary Brecka:What about red light therapy? You know, what are the effects of red light therapy? How do I tell the difference between what is effective and what is not? You know, what are some simple, easy ways to address a lot of the consequential things that we face, migraine headaches, for example. um so on there you'll see that i talk about addd adhd ocd anxiety gut issues um i talk about sports performance um and this is all coming from an evidence-based background or from my understanding of having read you know medical records for the better part of two decades what's next for the brand are any exciting plans well you know it's all about impact now okay you know how many people can I get this message to?
38:50Gary Brecka:That's why I'm losing my voice right now. I've been talking for four days in four countries. I have an endless amount of energy for this. So right now, if you were to consolidate three terms, anti-aging, longevity, and wellness, because people use these terms interchangeably, you would encapsulate the greatest shift in human interest in recorded history. And what that means is for the first time, a single area of human interest has eclipsed all of the top five categories combined, which is sports, entertainment, travel, leisure, and culinary. And so this tells you how much people are waking up to this wellness journey.
39:32Gary Brecka:And I think there's such a paucity of good information out there to tell people, where do I go to get information? How do I sift through the noise? You know, I'm on ChatGPT, I'm on Google, trying to figure out what my next steps are. And that's why I try to bring that advice to distill it down to as simple as possible. If you're enjoying this episode, please subscribe. We've just launched the SL Man YouTube channel. So please go ahead and subscribe there. And you can get all the content that we're making right into your feed. Thanks so much. Right. Let's finish with some quick fire this or that questions.
40:09Gary Brecka:This or that. Okay. Please end the debate for us. How many coffees a day are we allowed? Three coffees, last one, not after 2 p.m. Okay. Yeah, that's... Three coffees before 2 p.m. That's a lot of coffees in a quick space of time. I like it. You said maximum. Yeah, yeah, that's fair. NAD +, fad or fantastic? So good for some people, not good for others. Genetic test will tell you how well you methylate. Some people produce healthier levels of NAD +, and need the precursors NMN, nicotinamide mononucleotide, um nicotinamide riboside um or nicotinic acid and so by testing you'll know which one's best for you okay cool growth peptides versus protein so protein i think is overrated it's really the amino acids that we're after so all protein regardless of its former origin is converted into amino acids so very often i will skip the protein and go directly to the amino acids i take a an essential amino acid supplement every single day.
41:15Gary Brecka:It's called Perfect Amino. And I take it every single day because it's the equivalent of 29 grams of whey protein, but it doesn't break it fast. The other quick myth I'll dispel about protein is that you cannot target direct protein in the human body. So we don't eat our nails to grow our nails. We don't need our hair to grow our hair. And sadly, we can't eat collagen to grow collagen. Collagen is great for you. and I'm a big fan of collagen protein. But because you put collagen into the body in a protein form, does not mean it shows up as collagen in your skin or elastin or fibrin. What happens is it gets converted to amino acids and then the body may build collagen from it, but it may also build a natural killer cell.
41:56Gary Brecka:It may do something else with that protein. That's interesting. Yeah. So people taking it, it's not always directly connected. The reason why we have a protein equivalent, you probably heard one gram of protein for every kilogram of body weight, that's a very common one, is to get to the amino acids. Amino acids are the building blocks of proteins. So if you have the essential amino acids, you can build any protein structure in the body. Are peptides in your... Oh my God, I'm a huge fan of peptides. Huge fan of peptides. I mean, peptides, the vast majority of peptides are made endogenously by the human body.
42:33Gary Brecka:GLP-1 is a peptide. We have a trillion dollar industry on the backs of a hormone that we produce in our gut. Insulin is a peptide. You may have heard of the peptide GHKCU. We produce that in the body. So peptides are amino acids that are signaling molecules. I am an extraordinarily huge fan of peptides. It's an exciting area. It's a great area. Cold plunge or infrared? Cold plunge for sure. More sunlight or more sleep? More sleep. Okay. Okay. Walking or running? Walking, but changing your pace. Okay. So fast walk, slow walk, intentional walk, relaxed walk. By actually changing the pace of your walk, which takes you in and out of zone two cardio, put less stress on the joints, and you get all of the physiologic benefits.
43:25Gary Brecka:Maybe incline, decline. Oh, yeah. Incline, decline, if you can do that. But changing the pace of your walking. Let's make up a term today, intermittent walking. You and I will go 50-50 on that. Walking or intermittent walking? Intermittent walking. Zone two cardio or HIIT? HIIT's cardio if you can. Okay. Morning workout or evening workout? Whatever works best for you. Some people are not morning people and they really struggle with morning workouts and that's okay. The challenge is if you don't get it done in the morning, most people won't get it done. but if you actually scheduled your workouts in the afternoon and you did them some people do much better working out in the afternoon they feel stronger especially men um you know will feel stronger in the afternoon and actually push themselves harder and get more out of their workouts so by trying to force it into the morning um we very often are limited on time because it just doesn't fit into our schedule and it's for some reason we feel like we have to knock it out in the morning, but that's not true.
44:30I'm definitely an afternoon workout person. And I kind of put that down to all of the coffees that I was having a Q &A and just needing to like release it at a certain point. But yeah, I'm definitely afternoon. Alcohol in moderation or not at all? In moderation, never within three hours before bed. Intermittent fasting
44:48Gary Brecka:or three balanced meals a day? So this is a tricky one because if you have low blood sugar, three meals a day is a must. Many, many, many women make this mistake. They eat too late in the day and it throws their hormones off. Especially their cortisol melatonin cycle. Some women, like my wife, have a low blood sugar, low hemoglobin A1c. They are not candidates for intermittent fasting. When you have difficulty controlling your blood sugar, if you have high glucose, you're insulin resistant, or you have high hemoglobin A1c, those people do excellent intermittent fasting. Okay. Is there an intermittent fasting schedule that you could get three meals in a day as well?
45:35Gary Brecka:Yes, you can eat between 12 and 8pm, which is a very common 12pm and 8pm. So you have an eight hour window. So you could eat every two hours. Wearables, essential or anxiety inducing? So this is another one that's interesting. This has come up recently, I feel. Yeah, there are people that have a gene mutation called COMT. Very common. These people are worriers. They worry constantly. They are also perfectionists. They also have a tendency to take all scenarios to the worst case scenario. They are also the people that ruminate at night and have difficulty falling asleep. those people with those characteristics usually do not do well with wearable data creates stress one gene c-o-m-t and that gene test test feels so seen yes you have the gene mutation i think they provide excellent data i mean what what's nice about wearables and i wear a whoop is that the data doesn't lie so you see wow every time i have two glasses of wine before bed, my sleep score is worse.
46:45Every time I eat right before bed,
46:48Gary Brecka:my sleep score is worse. Look at the difference between going to bed at 11 PM and 10 PM. It's only one hour, but it's a night and day response in my sleep score. So for that kind of data, it's invaluable. Yeah. And you can choose to ignore it if you want to. Yep. You can. One thing every man over 40 should start doing today. Creatine hydrochloride, creatine HCO. The most overrated supplement? Non-methylated multivitamins, meaning multivitamins that are not in the methylated form. One multivitamin for everyone. That is so overrated. Because it's not as bioavailable. It's not as bioavailable, and some of the nutrients may even be causing harm because your body cannot break them down.
47:35Gary Brecka:Polic acid is a big one. Okay. The most underrated supplement? methylated multivitamins i think that term methylated means all the difference in the world bioavailable targeted methylated assumes your body can't break it down and it gives you that nutrient in the already broken down form so the next question i think i know the answer to what products would you like to put in a black hole oh uh well i would like to put uh multivitamins in a black hole that are not methylated because I think very, you know, you, by the way, you can tell this because you'll take them and your urine will be bright fluorescent orange or bright fluorescent yellow.
48:17Gary Brecka:You might even have a greenish tinge to it. You're just paying for expensive urine. I've had that with the B vitamins. Yeah. You'll see that with the B vitamins, B12. That means you're not absorbing it. It's not bioavailable. If it went into the tissues, it wouldn't show up in the urine. What's the biggest health myth people still believe? one size fits all. And finally, if you had to choose adding years to your life or life to your years, what would you choose? Oh, life to the years. For sure. Great. Thanks so much, Gary. This has been great. It's been a fascinating conversation. I've certainly come away with plenty to think about when it comes to health, performance and longevity.
48:58If you've enjoyed this episode, don't forget to subscribe to the S.I. Man podcast, leave us a review and share it with someone who might find it useful. You can also find more expert advice and lifestyle content over at slman.com. Thanks for listening. We'll see you next time.
From the publisher
In this episode of SL.Man, Harvey sits down with renowned human biologist and longevity expert Gary Brecka to separate fact from fiction and explore what it really takes to live a longer, healthier life. From personalised nutrition and biohacking to sleep, longevity and supplements, Gary cuts through the wellness noise and shares the science-backed habits that can transform your health, boost performance and improve recovery – including the one thing every man over 40 should be doing today.
If you're interested in wellness, performance, nutrition or longevity, this is an episode you won't want to miss. Don't forget to like, comment and subscribe for more conversations with leading experts on health, fitness and modern living from SL.Man.
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Harvey James | @harvjam | https://www.instagram.com/harvjam/?hl=en
Gary Brecka | @garybrecka | https://www.instagram.com/garybrecka/?hl=en


