In short
Two long-term Zoe Nutrition members explain what happens when you start eating healthy, and how Zoe’s science-based approach differs from calorie counting and restrictive diets. They discuss motivation, sustainability, gut microbiome testing, and practical strategies (meal building, planning, displacement, and drinks). Scientists Tim Spector and Sarah Berry add evidence about gut health, inflammation, mood/energy, and processed foods like bacon.
Guests (backgrounds)
- Becky Tucker (51, Poole, Dorset): joined Zoe Jan 2023; struggled with weight since pregnancy at 17; tried Weight Watchers, Slimming World, calorie counting; used artificial sweeteners.
- Mark Payne: property lawyer; mother was a nurse; focused on health more than weight; read Tim Spector’s Spoonfed; joined Zoe after waiting list; skeptical until results.
Key claims
- Calorie-restricted diets work short-term but drive regain (cited stats: ~50% regain within a few years; ~70% within five years).
- Weight loss is a byproduct of improving food quality; mood/energy and hunger improve early.
- “Nothing is off limits,” but healthy additions displace less healthy foods.
- Processed red meat (e.g., bacon) increases chronic disease risk; avoid regular intake.
Notable examples
- Becky’s “sliding door” after testing (March 2023); she switched away from sweeteners and learned to use fats/olive oil.
- Mark’s shock at “blood fat bad” results; lost 7 kg in two months; gut health score rose from 44/100 to 88 after retesting.
- Microbiome test: “poo in the post” DNA analysis; members cite improved gut health scores.
- Bacon discussion: occasional/sprinkles likely fine; regular UK/US portions are “high risk.”
Written by AI. May contain mistakes. Listen to the episode to check what was said.
Chapters
Tap a time to open that second in VONew Year, New Goals
0:45 to 1:46
Setting health-related resolutions and introducing guests.
“Because once you can see the goal, it's much easier to score.”
Introducing the Guests
1:46 to 2:12
Meet Becky Tucker and Mark Payne, who share their health journeys.
“Becky and Mark, happy new year, and thank you both for joining me today.”
Quickfire Round: Diet Opinions
2:12 to 3:42
A fast-paced Q&A session probing guests' views on diets and health.
“And Sarah and Tim, thanks for being here, and I hope you didn't overindulge last night.”
Becky's Journey with Dieting
3:42 to 7:14
Becky recounts her struggles with dieting and finding Zoe.
“This is like day one of trying to do it.”
Mark's Health-Focused Experience
7:14 to 9:21
Mark shares his focus on health over weight in his Zoe journey.
“At the starting point of Zoe to now, I very quickly realized that it was a natural byproduct, the losing weight, actually.”
Insights on Diet and Health
11:09 to 14:00
Discussion on dieting, weight loss, and the complexity of health.
“And I think that's a story we're hearing more and more from people following the Zoe program, who when they were consuming their previous diet, it was just the normal way of feeling on their diet.”
The Complexity of Gut Health
14:00 to 15:01
Learn why calorie counting may not suffice for health, focusing on gut health.
“And of course it missed the complexity of gut health, which a recent discovery is this sort of missing link between why just basing it on calories didn't work.”
Personal Health Journeys
15:01 to 17:41
Explore personal stories of diet struggles and realizations about food choices.
“And I always tried to shy away from things I could see clearly were processed.”
The Importance of Food Displacement
17:41 to 18:54
Understand the concept of displacement in healthy eating and planning.
“And that's, you know, you fall off the wagon again until you put on loads of weight and then you're back on it again.”
Navigating Forbidden Foods
18:54 to 20:04
Discuss the balance of enjoying prohibited foods while maintaining health.
“You know, I have a little nut pot that I take to the theatre and that keeps you going until you can eat a proper, healthy plate.”
Show all 20 chapters
The Risks of Processed Meats
20:04 to 21:58
Learn about the health risks associated with processed red meats like bacon.
“Quite a few of us have probably been having some bacon over the last month.”
Exploring Dietary Changes
21:58 to 24:45
Hear about unexpected dietary shifts and increased plant-based eating.
“distill down is it's about thinking about the overall meal again and not demonising or denying yourself one specific part of it.”
Understanding the Microbiome Test
24:45 to 28:00
Get insights on the microbiome test process and its significance for health.
“So thank you for sharing all of those stories.”
Transformative Experiences of Dietary Change
28:00 to 31:48
Learn how individuals adapted to new dietary habits and the impact on their health.
“And then when I retested, it was 88 and I was like jumping for joy.”
The Journey of Learning and Adaptation
31:48 to 38:05
Explore the ongoing journey of understanding and adapting to healthier eating patterns.
“But it was a lot of fun from the beginning, I found.”
Long-Term Sustainability and Health Impact
38:05 to 40:45
Discover how sustainable dietary changes can affect long-term health and well-being.
“There was no going back for me at that point because I realised that this wasn't just about weight.”
Empowerment Through Knowledge and Science
40:45 to 42:03
Understand how new insights into nutrition empower individuals to take control of their health.
“I can remember, you know, these things are healthy and those less so, but that's only part of the picture.”
Empowerment Through Healthy Eating
42:03 to 45:50
Discover how changing your diet can empower you and improve your energy and mood.
“And how do you understand these stories about energy?”
Practical Tips for Healthy Eating
45:51 to 49:38
Hear practical tips from guests on how to successfully integrate healthy eating into your life.
“Just a little pot, you put a mixture of roast chickpeas perhaps dry roast peanuts, whatever nuts you like in there.”
Reflections on Personal Dietary Changes
49:39 to 53:56
Listen to reflections on the journey of dietary changes and their impact on lifestyle.
“You just have to be a bit more intentional about that.”
Transcript
Automatic transcript. May contain errors.0:00Welcome to Zoe Science and Nutrition, where world-leading scientists explain how their research can improve your health.
0:13The new year feels full of potential, fresh routines, ambitious plans, and a quiet promise to ourselves. This year will be different. For many of you listening to this podcast, your focus is making lasting changes to your diet, to improve how you feel, how you look, and how many more healthy years you live. But setting big ambitions is easy. Following through is the tricky part. So to give you the biggest boost on achieving this year's resolutions, we're doing something we've never done before. We're bringing on two everyday people who started their journey two years ago to show you what's possible.
0:51Because once you can see the goal, it's much easier to score. In today's episode, I'm joined by Becky Tucker and Mark Payne, two individuals we found by putting out a call to our community. Each of them has spent the past two years consistently putting Zoe Nutrition principles into practice through busy seasons, stressful weeks, celebrations, setbacks, life. And somewhere along the way, both of them hit a moment where everything changed. where becoming people who simply eat well became part of their identity. In this conversation, we'll learn how they stayed motivated and on track and the lessons learned and strategies used that worked for them and the unexpected ways that everything changed.
1:38If you're trying to make a change this year or trying to stay committed to one, perhaps today's episode could be the spark you need. And we're not doing this alone. In our fully packed studio today, are Professor Tim Spector and Professor Sarah Berry, two of the world's leading experts on gut health and nutrition science, here to explain the science behind Becky and Mark's success and how Zoe's principles can support long-term health in the real world.
2:06Becky and Mark, happy new year, and thank you both for joining me today. Thank you. Pleasure to be here. And Sarah and Tim, thanks for being here, and I hope you didn't overindulge last night. Oh, I'm such a good girl, Jonathan. and it's Tim that was on the tequilas, far too many. Shouldn't be telling secrets. So Becky and Mark, I think you know this, but we have a tradition here at Zoe on the podcast where we always start with a quick fire round of questions. And we ask you to give us a yes or a no or a one sentence answer if you have to. You willing to give it a go? Definitely. Sure. All right.
2:43Becky, in your experience, do diet plans work? Yes and no. They work in the short term and then they absolutely do not. Mark, can you transform how you feel by changing what you eat? Yes. Tim, to lose weight, should you count calories? Absolutely not. Sarah, can food affect your mood? Absolutely, yes. Mark, is it possible to eat healthily without feeling restricted? Yes. Mark and Becky, to both of you, what's one belief about health or food you no longer hold? I previously thought that what we were being told by big food companies was correct, and I no longer believe that. I would say that fat is not bad.
3:36Some is, some's good, some's in the middle. That was a big revelation for me. Becky and Mark, thank you both so much for coming in. We always have all of these scientists on the show, but we thought it would be great on New Year's Day to do something a little different and almost turn it around because so many listeners today are embarking on like a change. They've made some sort of resolution. This is like day one of trying to do it. And we thought it would be really great actually to have two people who've been on a health journey with changing their diet that you've sustained for a few years now to share what works and the pitfalls and also to recognise that it's not an easy thing to make these habit changes and you've both tried a lot of things in the past as well.
4:23So first of all, Becky, would you tell us a little bit about yourself? Yeah, sure. So I'm Becky and I live in Poole in Dorset, so nice sunny location right by the beach, which is really lovely too. Good for wellbeing, good for health. And on January the 1st, 2023, I joined the queue to become a Zoe member. At that time, that you had to kind of put your name down and get your space. And so I waited. And on the 6th of March, 2023, it is a sliding door moment in my life. I did my testing. But I guess what took me to that point was a very, very long journey of trying lots and lots of other programs and diets because I struggled with my weight.
5:07My weight fluctuated right from having my son at 17 through to 2023, I guess. And that is a journey through lots of diet plans that didn't work for me. My quickfire round question when I said, yes, there are diets that work. Yes, there are. You can absolutely lose weight. Can you maintain that weight? Absolutely not. It's really, really difficult. I lived off of a diet of artificial sweeteners because that gave me the little bit of pleasure in the tiny amount of food that I was allowed to eat, which actually fought against everything that worked for me, I later found out as part of Zoe. When did you first try this first diet plan you're talking about?
5:52I started my life trying Weight Watchers and I was 18. I'd just had my son and I had put on that normal kind of pregnancy, post-pregnancy weight and was struggling to get it off. I'd seen my mum actually do Weight Watchers for almost all of her life as well, up and down with weight. All right when you're on it, because you can do it. In real life, you can't maintain it. And you're eating rubbish essentially to be able to have a little tiny bit of pleasure from life. And by that, it probably isn't pleasure like I know it today in terms of food because I've always enjoyed food and I still enjoy food.
6:34That's really part of what Zoe gives you, I think, is that sense that you can eat food and you can eat real food and still maintain the weight that I've done for over two years. So from my perspective, yes, I've tried Weight Watchers, I've tried Slimming World, I've tried calorie counting, all of those. I'm going to ask a question that my mum would tell me I'm definitely not allowed to ask. Would you be able to share how old you are today? Yes, absolutely. I'm 51. So that's a long journey. So you're saying like throughout this period was just a constant cycle of going onto a diet plan and coming off without it working?
7:14Yeah, absolutely. At the starting point of Zoe to now, I very quickly realized that it was a natural byproduct, the losing weight, actually. I didn't do it to lose weight at that point. I did it because I'd recently read some books that had kind of made me think, oh, actually, there's more to diet than just what calories you eat. And Mark, could you tell us a bit about your story? Sure. So my name is Mark. I'm a property lawyer. I've always been interested in food and felt that it's important to your health. My mother was a nurse and brought us up that way. I've never had a sweet tooth. I've never snacked.
7:58I don't eat cakes, biscuits, etc. I've also felt a little bit overweight. But for me, the Zoe journey was less about weight and more about health. The other thing that happened was I read Tim's book, Spoonfed, and found it really fascinating. And this point about, you know, never knowing what's really healthy or isn't. Is salt healthy or isn't it? Is coffee healthy or isn't it? It can drive you mad if you care about that. And then Zoe came along. I was a bit later than you and I had to go on the waiting list to join Zoe and do the tests. I got the results in August, 2023. So what really shocked me was the blood fat bad reading.
8:35And I was so upset because I was looking at a life where I wouldn't be able to eat bread, pasta, red meat, all these things I loved like bacon and steak and things, fish and chips. It seemed to me as though three quarters of my diet was really unhealthy for me now. But at the same time, part of me realized I had to do this. So I started on the journey. And I'm not someone who does things by halves. If I'm going to do this thing, I'm going to do it properly. And I've done it ever since. Now, the first two months were fascinating because first of all, I lost seven kilos, which was helpful because I was a bit overweight.
9:15I have stayed that same way ever since because I feel I've eaten incredibly healthily following Zoe for over two years since then. It was quite amazing, but I got far more energy. My skin's better. I felt transformed actually. And I was quite skeptical, by the way. I was wanting to see evidence and it It was really, for me, the other way around. The evidence was bombarding me. It was obvious this thing was working. And that's why I've kept it ever since. Sarah, do these sorts of stories sound familiar to you before even coming to Zoe? For our scientific co-founder, Professor Tim Spector, the quest for better brain health is deeply personal.
9:57Tim watched his mother live with dementia for years, and he's long known about his own genetic risks for high blood pressure. Recently, Tim underwent comprehensive brain testing. And despite his expertise, his scans revealed something startling. High exposure to microplastics. It was a wake-up call that our environment and our biology are under constant pressure. This led Tim to double down on the nutrition principles that we've developed here at Zoe that protect cognitive longevity. And we've compiled those principles into a brand new guide called Eating for Better Brain Health. This isn't just generic advice.
10:29This is your brain gut blueprint. Inside, we break down five core strategies like pivoting your protein to clear your vascular highways. We even include the kimchi kick breakfast recipe to lower your inflammatory response. As Tim says, for 40 years, we've been going down the wrong path, treating the brain as something different from the rest of the body. Stop leaving your brain health to chance. Learn exactly how to rewire how you think, starting with what's on your plate. Download the guide for free at zoe.com slash brain health. that's zoe.com slash brain health or click the link in the episode description yeah absolutely i mean starting with becky first this cycle of losing weight putting it back on losing weight going through these processes of calorie restricted diets that work exactly like she said in the short term but not in the long term we know that there's very clear evidence that 50 percent of people who go on calorie restricted diets put all the weight back on within a few years 70 within five years it's not a sustainable method of weight loss and it's not a healthy method of weight loss either our bodies work so hard to maintain the weight that you're at you know by as soon as you restrict your calories increasing your desire for food increasing your appetite reducing your metabolic rate and so that's why we really focus at Zoe on the quality of the calories and not the quantity of calories and why weight loss just like with Mark tends to be a byproduct of that and what I loved is what Mark said about how he felt because this is something that I think is great through changing your diet how people feel better so not only has some of his clinical measures potentially improved it's the fact that you said you feel even more energy, you feel better mood, etc.
12:22And I think that's a story we're hearing more and more from people following the Zoe program, who when they were consuming their previous diet, it was just the normal way of feeling on their diet. They didn't realize there was a better way to feel. And Tim, why have we been told for decades and decades that the key thing is, you know, energy in compared to energy out, just focus on calories. That's definitely been government advice, sort of all around the world? We were always looking for a very simple explanation for people gaining weight or losing too much weight. And so it came after the war.
13:00It was all about deprivation and kids, babies weren't getting enough general energy in that they couldn't grow and maintain their weight. So it was a sort of logical thing to say, well, it's very complicated, but let's just reduce it to something that we can approximately measure and give some guidelines to people. And it came about like that. It was a simple concept to sell to people, although it was based on flawed science and evidence, when it turned out to the practicalities of people's individual experiences. But overall, it was a simple thing to say, yes, women need 2 ,000 calories, men, 2 ,500, one size fits all, nice and easy, guidelines done, move on.
13:49And you blame people if they go over it and you'll reward them if they stay under it. But it never worked. And essentially it was missing this huge complexity of human metabolism and the complexity of food. And of course it missed the complexity of gut health, which a recent discovery is this sort of missing link between why just basing it on calories didn't work. I think as well, Jonathan, the concept of energy in, energy out is compounded by the food landscape we now live in. And so we're surrounded by very different types of food that just encourage this overconsumption and have a different kind of calorie effect than the kind of foods that we were consuming a hundred or more years ago.
14:35I did actually want to ask about Mark's story, which is obviously focusing on health, which is really interesting. You're telling the story of trying really hard to deal with your health for like three years and then still staying in this sort of pre-diabetes range, despite the fact that you felt that you were doing all of this. Are you surprised to hear that this isn't just about weight, but this is very much about health? Yeah, absolutely. And something that I picked up on that Mark said quite proudly, you don't snack you don't eat cakes and biscuits but actually there's all the other foods that you could be eating that we now have in our current food environment that could be really bad for you because of the way many foods are processed so it would be interesting to know what kinds of foods you were having even though you didn't snack and you didn't have a sweet tooth yes i mean things like bacon i didn't eat a huge amount but but i did like it quite a lot i tended to like meat a lot and and eat plenty of meat i of course i always ate vegetables but not enough not in the right balance i know that now i loved fish always the cutting out the fruit was obviously a mistake i was doing it to keep the sugar down did you eat low fat foods at all or low calorie foods they sort of attract you when you went to the no i never i never believed that actually the low fat thing.
15:58And I always tried to shy away from things I could see clearly were processed. So take bacon, and maybe I was completely wrong, but I assumed bacon wasn't very processed. I assumed it was just a bit of meat. I knew there were nitrates in it. And that was probably completely wrong, you'll tell me. But I thought that wasn't too bad. And the same with red meats. And I bought good quality ones, and I always tried to buy organic. So I did all the things I thought were good for me and healthy. And, you know, sometimes I was right, and often I wasn't. I think conversely for me, I didn't do any of those things.
16:31I was driven by a diet program that said for these many points per day, Becky, you can have whatever you want. And whatever you want was mostly ultra processed. Now I reflect back on that. So in the UK, we have the Mars bar and I can remember working out that on my points for a day on Weight Watchers, I could have three. I could live and that would be okay. That would be okay. And you know what? I'd lose weight. And looking back on that, how do you feel? I'm horrified. It actually makes me feel quite emotional because the reality of that at the time was almost a, well, do you know what? I'm addicted to that.
17:15So yeah. And I will use that word addicted because I was. I was addicted to sugars in all the wrong way. And I think that's sad that, you know, the information that I was given at that time, I didn't realize, A, that I was addicted to those things. And that actually all that made me do is make life really difficult for myself because, you know, you could have three bars, but then, oh, I could have another one now then and so on and so forth. And that's what happened. And that's, you know, you fall off the wagon again until you put on loads of weight and then you're back on it again. But also, even if you were managed to keep the weight off, the food that you're eating, the mass blood that you're eating will cause serious long-term health effects.
17:58And so again, this is why we have to move beyond calorie counting. We have to think of the overall quality of the food. Do you mind if I mentioned something that I think might help people? Because it's one of the things that's helped me the most. I mentioned that at the start, I was really, you know, really demoralized about all the things I'd have to cut out of my diet, and it felt awful. The key to that has been displacement, a concept that you've explained to me, which is actually that as long as you can eat enough to be satisfied, you don't feel deprived and you can choose so many foods that I like.
18:30And if you eat those, you don't miss the bacon rolls. Why? Because I'm satisfied. I'm happy. I love the food I eat. I love beetroot and preserved lemons and all sorts of healthy stuff. You just can't buy the convenience quick foods anymore. Sometimes you don't have enough time to eat properly, so you buy a sandwich previously. And now I really can't. So it takes a bit of time to adjust practically to that, like make a little lunch box of healthy food that you can eat quickly at your desk for 10 minutes. You know, I have a little nut pot that I take to the theatre and that keeps you going until you can eat a proper, healthy plate.
19:03I think that's a fair point. It's planning ahead. And that's what Zoe teaches you to do. I travel a lot for work also, and mainly in a car. So if you imagine driving on a three, four hour drive from where I live in Dorset to Birmingham or wherever, the only options you've got along the way are service station. Have you looked at what's on offer in a service station shop? Because there is nothing for me there, actually nothing. And I think that's horrifying. It's, as Mark says, it's planning ahead. Yes, I've got my obligatory pot of nuts as well. So Sarah, how do you think about things being forbidden?
19:41So I think absolutely nothing should be off limits. So if you want to have bacon, have it. But very, very, very occasionally is about what you're adding to your plate. Because exactly like you said, by adding in healthy foods, you're naturally going to displace the less healthy foods. the more you deny yourself things whether it's calories whether it's specific foods the more you're going to crave it and so don't totally take everything away cut down the foods that are bad replace them with the healthy foods and let yourself have the odd treat you know a little bit of what's bad for you occasionally can be good for you bacon's come up a number of times a lot of listeners may be saying what is it about bacon that it's been given all the hard wrap after oil is January the 1st.
20:28Quite a few of us have probably been having some bacon over the last month. What's the story there? Oh, a bacon sarnie after a hangover, Jonathan. Nothing beats it with loads of butter. But we know processed red meat, like bacon, like ham, increases our risk of many chronic diseases. Particularly cancer is clearly linked with increased rates of cancer. And we're not sure exactly why it could be a lot of the chemicals in there as well as some of the unhealthy fats. But if you're having that regularly, several times a week, then that gives you this extra risk. Okay. So this is genuinely, this is like really a high risk food.
21:05Yeah. Across the board, it comes out in all the studies as being a high risk processed food that you really want to be avoiding having regularly. Having it once a month or having tiny sprinkles of it you know as you do if you go to italy or or spain where you can't avoid a little bit of this um it is probably fine but having it in in the amounts that we have in the uk and the us i think uh definitely bad for you and also thinking the overall quality of how you're having that so imagine the traditional british or american way of having that bacon it was probably with some white bread it's probably with some tomato ketchup with some butter that's not very healthy or you can have the more Mediterranean style way that they do include some red meat in a small amount but alongside that you'll have beans, pulses, vegetables, extra virgin olive oil.
21:57So that's something else that I hope you found through the science that we try and distill down is it's about thinking about the overall meal again and not demonising or denying yourself one specific part of it. It's really interesting to hear the kind of meat discussion because I accidentally became vegetarian when I went on Zoe. And I mean accidentally because I ate less and less and less meat, not through choice, but because there were other things that I wanted to eat more of. And that has just been revolutionary for me, I think, that I didn't intend to be vegetarian, but I'd go weeks without having chicken or steak or any of those things.
22:40So much so that in the end, I just thought, well, I'll just as well go the whole way and not eat meat anymore. And I chose to do that because I can then eat more of the things that bring me joy. A plate of vegetables and nuts and seeds and my daily 30, I'm going to get that in because I have that every single day. All of those things give me more pleasure than meat does. So I choose not to when i transitioned to many a plant-based i sort of said oh well you know i can have meat when i want it but i found i was wanting it less yeah because you've sort of perhaps changed your palate you know as you've gone on and the idea of eating some enormous steak which people you know listening might say i could never do without it but actually once you you do start to have all this range of other plants someone offers you a bite you might yeah well that's great but i find I can't have much more than that now it's interesting how you do change I mean for me I I still love meat and I concentrate my efforts now on venison which I know is really healthy and and turkey and chicken and then fish I love and eggs and cheese and all of these things so I definitely haven't turned into a vegetarian but it's true I eat far more plants and one of the things that struck me recently is how in the old days the way I ate before and maybe how most people eat, you tend to have maybe three things on your plate, if you think about it.
24:09Fish and chips, and you know you've got to have something green, so you put peas in as well, let's say. Or steak and chips, and again, perhaps a green thing. Three things. My plates almost never have only three things anymore. I mean, when I'm making up a plate of salad or whatever, it's got 15 things on it. It's got beetroot and maybe three herbs chucked on top, and tomatoes, and so on and so forth. There will be protein there too, but smaller amounts, a bit like you said, Tim. But it's actually more fun now. The food's more interesting, much more varied. You've got this thing where you've got to eat lots of different types of plants.
24:41I find that a great game. So last week, I think I had 81, believe it or not. No way. Honestly. That's better than Tim, I think. 81. Yeah, beats me. So thank you for sharing all of those stories. And I think there are going to be a lot of people listening for whom those stories resonate and looking for inspiration as we begin the new year. So I'd like to talk maybe about those first few months. And some of our listeners may know that one of the first things you do as a member is to take a microbiome test. And we talk a lot about the science and the results of the microbiome test, but it has to be said that we don't tend to talk a lot about the process of the microbiome test.
25:17Mark, can you guess why that might be? Because it's all about testing your poo, isn't it? Do you want to talk us through what you have to do? Yes. Okay. So you have to collect a little bit of your poo, which isn't so hard, actually. a tiny little bit pop it in a little tube and send it off in the post it's actually very easy it didn't put you off when you first did it or thought about it no not at all we make it really nice though we give you a little hammock that you put on the toilet how did it go for you becky it was fine you pop it off in the post and it took about two weeks i think to come back the results and you get a very comprehensive report of lots of very long names that i can't pronounce which I'll leave to these guys.
25:56I was going to say, Tim, can you explain a little bit about that gut microbiome test and what's going on from the point you put it in the mail to the results coming back? Yes. So we pioneered this over 10 years ago, this poo in the post concept. A little bit of poo, which is a tiny quarter of a teaspoon, goes into this liquid which preserves it and stops it degrading. You get it in the lab and then essentially we extract the DNA from the rest of the stuff. And the rest of the stuff actually is dead microbes, most of it. The DNA from that then goes into our analyzers. Every single microbe has its own DNA and that goes into this big puzzle, basically, when our computers then link those DNA structures to the database and work out what the microbes are in your particular sample.
26:51And that's a huge computational exercise. We're trying to work out every gene in every microbe, you know, what it's called and which one is then associated with. So we sort of reconstruct your gut microbiome. It's really clever. Many gut tests still only look at one gene in every microbe, but we do every single gene. And so it's very comprehensive. and then from that we then work out now how many good bugs you've got and how many bad bugs this is based on our study which we published in nature 50 good bugs 50 bad bugs and we look at the ratios and that is now the best way of looking at your gut microbiome it used to be i can't remember whether you did the test it was diversity and a number of different species do you remember what your results were?
27:40Yes, I do. My first ones were 630 and then 535 and then 550. What was yours like? I remember getting the overall gut health score, which was the first time I did it before retesting 12 months later, I think, was 44 out of 100. And then when I retested, it was 88 and I was like jumping for joy. The difference between that in 12 months. That's amazing. I doubled my gut health and I just thought, wow, that's just incredible. What was that experience in the first month or two, if you can think back? Because you were describing coming from this world where as long as you only ate three chocolate bars a day and nothing else, this was fine.
28:22So I think probably the advice that you were suddenly getting from Zoe being pretty radically different. The magic began for me when I got my results back because it was astounding. So I hadn't realised at all that I was very poor at processing sugar and yet lived off of a diet of artificial sweeteners. So it's no surprise I was struggling and really good scoring and ability to be able to deal with the fats. So already I was looking at some figures that were the complete opposite of my diet. So everything that I was doing basically would have scored horrendously for me when I was scanning it on the app.
29:01So it took a little while for me to kind of get my head around that, to look at the consequences of if I ate that, my score would plummet versus if I ate that and it would shoot through the roof. So it was a learning process. And I always say to my grandchildren, if you try something 10 times, you'll get to like it. But I had to live by that myself at that time because it did take a few weeks, I would say, to actually kind of turn around what I wanted to eat and how I wanted to eat it. I did it. And actually, it was surprisingly easy. But at the time, it was quite a stand on the edge of a cliff moment going, this is going to be hard.
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29:42Did you eat more fatty foods then? I did. So a bit like Mark said earlier on was my understanding of what fatty foods did to me. I'd avoided fat at all costs ever, absolutely avoided it because I knew that A, it was higher in calories and B, it didn't score well on my Weight Watchers program. So if you were cooking food, for example, that involved anything meaning to be fried or whatever, what would you have done? I wouldn't have done it. Oh, you wouldn't even have done it? No. And today? Absolutely. And today I use olive oil every day of my life. And so it's about educating yourself, isn't it?
30:18It's about, you know, we're told that fats are bad for us and it's not true. It's simply just not true. On the contrary, in fact, for me, it's good for me. It actually is what my body processes well. And I've proven that to myself over and over again, day in, day out. But at that time, no, I wouldn't have done it. I would have just avoided all costs. Anything fried was just not on my agenda. And did you figure this all out on day one? There was a list of information somehow, and therefore you just magically turned the dial on 30 years of eating in a different way? No. So I think the value of Zoe is it takes you through that journey.
31:02So on my Zoe app, every day you'd have a new lesson to learn something new. And I was soaking it up at that point. I'd got this interest in what I was doing and how it was impacting on me. and so those lessons were just fantastic but it opens up a whole new world doesn't it suddenly you want to know more you know you realize you're feeling better suddenly and oh by the way you're losing weight naturally without having to worry about you know whether I can fit a Mars bar in at the end of the day or not and so I think it's just about learning and about you know being open to learning and not being scared by it yeah I mean I think you put that really well it was a journey and it took a couple of months to, you know, change the way you eat.
31:48But it was a lot of fun from the beginning, I found. And I started to see the positive benefits quite quickly as well. So I found it, in a way, I didn't find it hard because I was getting so much positive reinforcement and learning so much and basically feeling better from really quite early on. And Mark, I know it's a couple of years, but if you can imagine thinking back, Could you maybe talk us through a little bit what that experience was like? You got your results. You had this app. I had this shock, as I explained earlier. I was really down about it, thinking, oh my goodness, I'm going to have to change the way I eat completely.
32:23And so many things I thought were healthy, it really aren't going to be. And I'd look on the app and rice is zero and bacon is zero and all these things are zero. But I set off on this journey and I started realizing that there were tons of things I did like that were scoring 100, like avocados. I love avocados. So whereas before a little bit of you might have thought, oh, I know they're very high fat, so maybe I shouldn't have too many. Now, you know, in the 100 category, 75 to 100, eat as much as you want. I like that. Eat as much as you want. So I started eating more of the eat as much as you want things and a lot less of the, you know, things I could see now you should only have occasionally and so on and so forth.
33:03I found that actually, I found that description of the foods helpful. You know, the 25 to 50 and so on, have it regularly and so on. I found that helpful. And then at the supermarket, you know, I still like bread, though I don't, I eat a lot less of it now. So with the app, you can pick the bread that scores 46, the best I ever found, instead of a lot of bread scoring zero and have that and put avocado on it. And then the mixture gives you 80 points. Great. And so actually I found it liberating. I felt a lot less hungry less often on it and and then I was feeling all these physical benefits like more energy and You know not feeling constipated anymore and all of these things which put in a really good positive feedback loop Take a recent example until I know your new book on ferment and I and One of the podcasts I watched was all about fermented foods and I thought that sounds fun.
33:55Let's try that I honestly think my energy levels have had another 20 % boost from it, making sure that every meal I have, you know, a reasonable amount, not too much of fermented foods of various types. I think what I love hearing is how you use the app to build the meals, because we don't eat foods in isolation, we don't eat nutrients in isolation, you know, we eat a dietary pattern, and we eat meals. And that's something that's quite hard from a science point of view, to think about well how do you modify a score based on combining different foods and it's something because the science team we've worked really hard on over the last few years where you take an element like the bread although you're choosing a healthy bread so you're still having that bread but then how do you make even better by overlaying with healthy other foods like avocado like olive oil and so it's lovely hearing that that actually play out in real life it works really well.
34:51It took a while for me to get my head around that though, that food combining thing. I was always looking at the scores in isolation. So I'd scan something and if it scored over 75, yeah, it was good for me. I was okay with that. If I went and scored bread at 46, there's no way I would have bought that loaf of bread. Absolutely no way at all. Until I started to realise that actually put some avocado on it or some smashed peas. And suddenly you've got, a meal that actually is good from a fiber perspective, good from a fats perspective. And so the score creeps up again. And it sounds like in those first few months, you were very engaged with this app and you were doing what we would call now sort of mindful eating and you were sort of really tracking all of these meals in the day.
35:40Will you talk a little bit because I heard you talk about this score for the day, what I think we would now call the diet score. I mean, we were probably called a day score at the time. Could you just explain for a moment what that was and whether it was useful in any way? Oh gosh, it was definitely useful. I don't think I could have done it without it personally because it enabled me to learn as I went. It's simple, isn't it? If you know that you're aiming as a minimum for 75 per day, so you get a score of 100, each item you can scan in the supermarket, it gives you a score out of that 100. And you know that if your day is 75 or above, then it's a good score and you're in a healthy range and keep going and doing what you're doing.
36:22Without that, I think it would have been really difficult to navigate. How do you know what is good and what is not when you definitely can't read the packaging of something to know whether it's good or not, because all packaging tells you it's good, despite the fact it's absolutely not. I'd like to come back to present day, because you're talking about something that is a couple of years ago. And I think I think all of us around the table have had the same experience as I think many of our listeners, which is you try something for a while, you have very high motivation, you keep it up, but it's really hard.
36:55And then you give up and you go back to your old habits. And in the end, sometimes you're actually worse off than the beginning. So I think the million dollar question is sort of how are you feeling now and does it feel sustainable? and how have these changes influenced your health and your weight and how you feel after a couple of years? Maybe I can start with Becky and then go on to Mark. So what's been the impact after, if you compare yourself now with the day that you sent off the test? Yeah, I think definitely I feel like a different person in many ways. I think that my sense of well-being has really been impacted.
37:36So at that time, I was probably not very kind on myself in terms of, you know, I felt uncomfortable. I felt like I wasn't the right weight. And I was constantly questioning why that was the case and not really knowing because, you know, I tried really hard to lose weight. And it wasn't even just about the weight at that point. It was just about my health, the way I felt. And then I realised it was actually the diet that I was having then that impacted on my health. There was no going back for me at that point because I realised that this wasn't just about weight. This was actually about how healthy I wanted to be, doing the things that I love to do.
38:18So I can't go back to not being a Zoe advocate, if you like. for me I really like the app I like scanning it's easy it's just part of what you do every day now so it's just my life it's just what I do and I think it's not hard because you just kind of you know you ingrain it in part of what you do on a day-to-day I think that's amazing a lot of people will be asking but what about the the weight Becky because they're going to be skeptical call because after all, this is always a short-term shift and then it all comes back, doesn't it? Nope. Absolutely not. No, no. I've been the same weight for two years and I've never done that in my entire life, ever.
39:04That's just not a thing for me. I'd literally be up a stone, down two stone, up three stone all the time. So on a Weight Watcher, to give you an example, I would be okay between sort of six months and nine months and then I'd be back to where I was again very quickly as well. The minute you stop calorie restriction, all that weight just comes piling back on again. So I don't want to make it sound like a weight loss program because I don't feel like that about it anymore. But the way I eat now, I am not restricted. I eat exactly what I want, when I want. But the types of food that you eat mean that you don't want to binge eat.
39:44And I would binge eat in brutal honesty, I would binge eat beforehand. Being on a diet that was calorie restricted leads you to that. So it's a lifelong style for me now. It's not a diet or a program or any of those things. It's just the way I am. That's amazing. And so when you look at your life now, Mark, you've also sustained this for a couple of years. How do you feel today when you contrast that with you know the day that you decided to start Zoe I feel different too I as I say I've got more energy I feel really healthy um I don't crave food at all anymore it's brought so many lovely changes to my life that I'd never want to stop and and people say to me but Mark by now you know all the foods that are healthy and you know the ones that aren't is it still worth doing this app thing you know and and I think well yes because food is complex and always changing too So I want to know what that new thing at Waitrose scores, for example, and also the combinations.
40:46Your algorithm gives the answers. I can't remember all that. I can remember, you know, these things are healthy and those less so, but that's only part of the picture. Also, I find the time element, the cost really, apart from a very modest sum every month in money, but the other cost is time. And I find actually I probably don't spend any more than maximum 15 minutes a day, maximum, logging everything. And I've logged, you know, pretty religiously everything I've ate and drank since, you know, for two years plus from the beginning because I didn't see the point in lying to myself. About 15 minutes a day maximum.
41:24The new photo snapping as well is even quicker, which I really like. Tim, what are your thoughts as you're listening to these two stories? Well, I think they should be inspiring for many people. And it's mirroring a lot of people who come up to me after I'm giving a talk, saying how this different way of thinking about food has changed people's lives. And I think this is really what it's about. Both these stories about how previous beliefs were suddenly changed by what we're doing at ZOE. so it's not just a program or whatever but it is a whole different way of thinking about food which then has this amazing impact on health and that is is what i think is so inspiring for people so it means that it's not about people's weaknesses or failures or whatever it's just people were told the wrong things and were trying to do the right thing and they were just being misled by you know big food companies by out-of-date guidelines by the medical establishment who don't know enough about this stuff so i think this is really all about people you know taking back the initiative themselves and i think what a lot of you're talking about is empowerment yes it's the ability that you know we're giving you some of these tools but the rest of it's up to you and you're deciding what to do with it and you want to change your lives and do it so So for me as a scientist and a doctor, it's the only time in my career when I'm realizing that we're helping so many people through the amazing science that we're doing and can have these results.
43:02Yeah, it's just fantastic. It makes me feel great. And how do you understand these stories about energy? because I think that remains one of the things that seems most surprising to me is that changing what you eat might affect things like your energy and your mood. Both of these guys are giving the similar and endless people coming up to me saying, yeah, one of the first things we noticed was a change in my mood and my energy. I didn't have that fatigue that I was always fighting before. And in medicine, we're not trained to ask people about energy levels or fatigue. It's like a no-no subject because, oh no, they're just going to grumble at me.
43:42I mustn't mention it. GP's worst nightmare is to ask about fatigue levels. But we now know that fatigue is linked to something that's happening in our immune system and inflammation levels. And I think this is relatively new science, but all these things that stress and fatigue are related to blood levels of inflammation that are just too high in the Western world, whereas they used to be much lower. And a lot of that is driven by the foods that we're eating. So our body doesn't process them well. It causes stress in the body. The immune system is just switched on all the time, dealing with a lot of these highly risk processed foods, things that we weren't naturally eating.
44:28And so these levels are one of the first things that drop when we get these blood sugar spikes under control, when we get the fat spikes under control, when we cut out all these additives. And that's why in all our studies, whether it's giving people daily 30 in a trial, whether it's just doing the standard Zoe plan, the first thing we notice is the mood and energy levels improving. And these guys are great witnesses to it, how important it is. And that just shows you how the link between the body and the mind. And something else we consistently see as well as mood and energy improving, we see hunger levels improving.
45:08That consistently people say, I feel less hungry. And that's something that both of you have said, that although you have naturally as a kind of byproduct of doing Zoe Lost's weight, you're actually feeling less hungry. Yes. Yeah. I mean, you say it's a byproduct, but it might be the reason just by switching what you're eating makes you less hungry. You're not craving stuff. therefore you're not going to be snacking on the rubbish food you were before. Mark and Becky, you both mentioned sort of the learning curve that you've been on to eat the way that you now do and I would love to share any tips that either of you have for the audience that sort of makes it easier to eat this way.
45:48You know I think Mark you mentioned a lunchbox for example. Yeah so the nut box is a good one. Just a little pot, you put a mixture of roast chickpeas perhaps dry roast peanuts, whatever nuts you like in there. Take an apple and have that to eat at the interval at the theater, for example, if you can't get a meal or just tide you over if you can't sit down and have a healthy meal for whatever reason. Can I mention soft drinks? So one of the problems with drinks is that they're nearly all incredibly unhealthy. I was left drinking water and black coffee and black tea pretty much, maybe with a bit of milk in.
46:23That's about it. It gets very boring so i wrote to zoe's nutrition coach back then saying other tell me what the soft drinks are that are the most healthy for me and back came momo kombucha and agua de madre and my fridge has rows of them they're brilliant the first one was a kombucha the second one was magua de madre that's a water kefir yeah tibikos so it's not very well known yet but it's a growing market and it's really delicious flavors. And if people haven't tried it, do go out and try some. Becky? I agree with everything Mark said, that all of those things I follow. I think don't be afraid to ask when you're out as well.
47:03So if you're in a restaurant, very rarely will I choose something standard from a menu anymore. I'll say, you do that with that, can I have some of that with some of that? And nine times out of 10, most restaurants are really happy to switch things up. So I think the message is go prepared. Don't expect to be able to find things that suit the way you want to eat in your local high street because it's tricky. Preparation is key, is the way that you make it integrate into your life, really. And tell me about breakfast, both of you. What does breakfast look like today? I try to vary it, actually, but my staple one is a live unsweetened yogurt plus kefir, always chia seeds, always a daily 30, almonds, pistachios because they're gut boosters, mixed nuts, some seeds probably, cocoa nibs, which I love, and berries on top for sweetness.
48:00Sounds beautiful. You mentioned they're gut boosters. Could you explain to listeners what that means? Yes. So one of the really nice things about Zoe is that they give you a list of, I think it's 20-ish for me anyway, gut boosters, meaning things that are good for the microbes in me that need to grow. I need more of them or to get some that I haven't got. And so I try and incorporate those into my diet and it's good fun, actually. Gut suppressors are the 10 or so bad things I should avoid unless I want to feed my bad microbes. And basically, I just do not eat them. You're much better behaved than I am.
48:37It's very impressive. Becky, what does your breakfast look like? It doesn't. I don't eat breakfast. So I continue to do 16-8, which is really interesting, actually, because I just like the way that makes me feel. For those that don't know, it means that I only eat in an eight-hour window. So my first meal of the day is usually about one o 'clock. And that's usually a savory offering. So that might be some vegetables or a salad with maybe some lentils or chickpeas sprinkled over with some nuts and seeds, of course. It's tricky, I guess, in the way that you need to kind of get in more meaningful protein.
49:15So being vegetarian, you need to think more carefully about that. And eating in a shorter window, meaning kind of two main meals a day, means that I also have to think more intentionally about replacing that protein content that I would have had with meat with things like nuts and seeds and pulses and lentils and chickpeas and all of those things that are really high in protein. You just have to be a bit more intentional about that. Final question. If you were able to go back in time and talk to yourself, let's say three years ago before you'd even heard of Zoe what's the one bit of advice you would give yourself given what you know today Becky why don't you go first um that's a challenging question I think the what if I had to narrow it down to one thing it would be don't believe what the packaging tells you that actually what you need to eat is um whole foods um that you know what's in the product rather than what the packaging is telling you.
50:19So avoid ultra-processed foods, I suppose, would be my kind of key takeaway. Avoiding ultra-processed foods is probably one of them, and also just not believing the fat story. The messages you get in general about health and what's healthy food are so baffling. And one of the things I find most valuable about Zoe is your honesty and that you follow the science. In other words, you tell us if there's something you think probably is healthy, but you don't know. You can't prove it yet. There isn't a good experiment. And so one of the things I really love about Zoe is it's one source of truth in this that cuts through all the confusion.
50:59And that's in some ways the most valuable thing about it for me. So if you guys say coffee is healthy, I believe you. One source of truth. Brilliant. Thank you so much. I think this has been really fun. very different from the sort of podcasts that we normally do. And I think really powerful. You know, if I think back about what I take away, one is Sarah explaining that nothing should be off limits, but that if you start to add all of these new things into your diet, you just naturally shift. And I thought, Becky, it was really interesting. You were saying I sort of accidentally became a vegetarian because I'm just adding in all of these plants and they're tasting so good.
51:36So I'm sort of squeezing the meat and squeezing the meat and you've ended up not eating at all. And Mark is saying, well, I really loved meat. But now again, I'm shifting to a lot of this stuff that's good for me, like the venison. And again, though, total amount is less because there's suddenly just all this other stuff that I like, which has definitely been my own journey as well, which is just that I actually think your tastes change a lot. And at least in my experience as someone who definitely ate tons of highly processed food, it's almost like your palate can't even tell that this food tastes good.
52:05And then you start to appreciate it and it does really shift. I love that. I love this story about feeling empowered. So rather than being told this is what you have to do, you just feel like you have answers that support you. And I guess the other thing that comes through really strongly is this idea of both having the information to understand what's going on and that you both have found being able to really understand specifically for an individual meal or a food, what's good allows you to make these decisions and changes, but critically that it's sustainable. You know, Becky, your story is really powerful, but it's also similar to stories I think that we hear quite often about many, many times embarking on a very restrictive diet, having a lot of short-term benefit, it being unsustainable, then feeling full of guilt and self-loathing, falling off it, you're incredibly hungry.
52:59So you put on all the weight or you like relapse in terms of the health measures that you might be looking at, Mark. And so I think the thing that probably I always find very sustaining, I suspect Sarah and Tim feel the same way is like this idea of making something that you can just keep doing forever, I think comes through really strongly. And then finally, you give some brilliant tips, which were new. So I love this idea of like a nut box, which might include like, I heard like roasted chickpeas, you know, have an apple take it for something where you're going to an event where you won't be able to eat until later.
53:31I think the restaurant, add extra vegetables, but also don't be afraid to ask to change. And I would just conclude by saying it's incredibly powerful to hear these stories. And I hope that there are a few listeners here who feel like actually maybe in 2026, this idea of doing something sustainable might be the best habit to try and embark on. And you are amazing examples of that. Thank you. Thank you. Thank you. As you can imagine, hosting this podcast, running Zoe, juggling family life, it all keeps me pretty busy. So I try as best I can to stay energized and show up well in all those parts of my life by fueling my body with the right food, by exercising, and by adding a scoop of Daily 30 to my meals every day.
54:19If you haven't heard of Daily 30 yet, it's the gut supplement designed by our gut health scientists here at Zoe. It's made of over 30 high-quality, hand-picked plants, including seaweed, fungi, and different types of fiber. Better yet, it contains ingredients that support gut health, digestion, and energy, which is ideal for packed calendars and busy lives. Simply add one scoop a day to any meal for an extra boost of fiber and plant diversity. And because it tastes delicious on just about anything and adds a satisfying crunch, it quite quickly slots into your life. becoming a daily healthy habit you'll always have time for.
54:58By the way, whenever we talk about Daily 30 as a good source of fiber, we're required to say that it contains four grams of total fat per serving. Obviously, that's all amazing healthy fats from plants. So, order yours today at zoe.com slash daily30. Thanks for listening and see you next time.
55:24Outro Music
From the publisher
What really happens when you stop dieting and start eating healthy? In this episode, we hear from two real people who spent years trying to “do the right thing” with food and still felt stuck.
Today, we’re joined by Becky and Mark, two ZOE members sharing their personal journeys. Each of them has spent the past two years consistently applying ZOE nutrition principles. Instead of relying on rules or restrictions, they embarked on a science-led journey with ZOE, focused on understanding their bodies. The results? Truly remarkable - ZOE became such an important part of their lives that, alongside 18,000 other members of our community, they became ZOE owners through our crowdfunding. So what changed, and did it last?
Alongside Professors Tim Spector and Sarah Berry, we explore how Becky and Mark stay motivated and on track, the lessons they have learned, and the strategies they have used to feel more in control and more confident in their everyday choices. As well as some unexpected shifts along the way.
It’s a conversation about long-term change, not quick fixes, and you’ll leave it with real-life examples of how to make healthy eating a part of your everyday life.
If healthy eating wasn’t about willpower or perfection, what small change would you start with? And what would help you take that first step this week?
Unwrap the truth about your food 👉 Get the ZOE app
🌱 Try our new plant based wholefood supplement - Daily 30+
*Naturally high in copper which contributes to normal energy yielding metabolism and the normal function of the immune system
Follow ZOE on Instagram.
Timecodes
00:00 Intro
05:20 The artificial sweetener trap no one talks about
08:20 The test result that caused panic
10:00 The stat that explains why diets “work”… then fail
12:05 Why calorie advice was “nice and easy”… and wrong
15:55 The “Mars bar” moment
17:10 The simple trick that stops you feeling deprived
18:10 Your biggest barrier might be the service station
19:25 Is bacon really that risky?
21:10 “Accidentally” becoming vegetarian
23:15 From three foods per plate to fifteen
24:15 The moment this turns into “poo in the post”
25:10 What actually happens to your sample in the lab
26:45 From 44 to 88 in one year
27:30 Why the magic starts after results day
29:10 The foods avoided for entire lives
30:00 The part of ZOE people underestimate
33:25 The meal-combining hack that changes everything
35:45 The daily score that keeps it sustainable
38:55 The claim people don’t believe: same weight for two years
44:05 The fatigue link your GP probably won’t ask about
45:47 The “nut box” rule (and what to drink instead)
52:05 How to make this last forever
📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Free resources from ZOE
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
ZOE’s Holiday Hosting Guide
Mentioned in today's episode
Gut micro-organisms associated with health, nutrition and dietary interventions, Nature (2025)
Ultra-processed food exposure and adverse health outcomes, BMJ (2024)
Have feedback or a topic you'd like us to cover? Let us know here.
Episode transcripts are available here.
