In short
The 1A podcast episode explains two re-emerging threats: New World screwworms (a parasitic fly causing lethal tissue infestations in mammals) returning to the U.S. after decades, and rising tick populations and tick-borne illnesses (including Lyme disease and alpha-gal syndrome).
Guest backgrounds
Leah Douglas is a Reuters agriculture/energy reporter covering the screwworm outbreak. Caitlin Jettelina is an epidemiologist and scientific communicator (Your Local Epidemiologist). Dr. Bobbi Pritt is a Mayo Clinic pathologist/clinical microbiology leader specializing in parasitic and vector-borne infections and tick-borne disease.
Key claims
USDA confirmed five screwworm cases in Texas and New Mexico; federal officials say beef is safe, but the cattle industry is on high alert. Tick bites and tick-borne diseases are increasing; tick season starts earlier, and Lyme disease cases have more than doubled since 2004.
Notable examples
Symptoms include painful, foul-smelling tissue infestation from screwworm larvae; tick bites can trigger delayed red-meat allergy (alpha-gal). Rancher monitoring includes watching for wounds, maggots, and abnormal behavior. Prevention advice includes DEET, permethrin-treated clothing, showering, and prompt tick removal with tweezers.
Written by AI. May contain mistakes. Listen to the episode to check what was said.
Chapters
Tap a time to open that second in VOThe Return of the Screwworm
0:31 to 1:42
Discover the alarming resurgence of the New World screwworm and its implications.
“In 1966, the United States declared victory over a destructive, flesh-eating parasite that devastated livestock.”
Reintroduction and Risks
2:54 to 3:20
Understand the government’s response to the screwworm outbreak and its risks.
“Each story you hear on Planet Money starts with a question.”
Symptoms and Treatments
3:20 to 5:27
Learn about the symptoms caused by screwworms and the treatments available.
“And let's start with the screwworm outbreak.”
Debate Over Responsibility
5:27 to 7:21
Examine the discussions on blame regarding the return of the screwworm.
“It really is a combination of things there.”
Impact on the Cattle Industry
7:21 to 9:14
Explore how the screwworm outbreak could affect the cattle industry economically.
“Here's Secretary of Agriculture Brooke Rollins at a press conference in Texas on Monday.”
Differences Between Screwworms and Blowflies
9:14 to 13:07
Distinguish the differences between screwworms and blowflies and their implications.
“So has that played a role in this resurgence?”
Consider This Podcast Intro
14:19 to 14:36
Introduction to NPR's afternoon news podcast.
“At NPR, we stand for your right to be curious, to make sense of the biggest story of the day and what it means for you.”
Introduction to Tick Season
14:36 to 15:05
Discussion about the increase in tick populations and associated health risks.
“Follow Consider This wherever you get your podcasts.”
Understanding Tick-Borne Diseases
15:05 to 16:01
Overview of tick-borne diseases and their impact on health.
“Experience is getting more common as the U.S.”
Types of Ticks and Their Hazards
16:01 to 18:12
Insight into different tick species and their associated diseases.
“So April is the start of tick season, and this year emergency room visits for tick bites were higher than in the 10 previous Aprils.”
Show all 24 chapters
Spread of Ticks in New Regions
18:12 to 19:56
Exploration of why ticks are appearing in new areas across the U.S.
“Is there anything distinctive about these ticks that might help someone identify them, Dr.”
Government Initiatives for Lyme Disease
19:56 to 21:41
Discussion on the initiatives to reduce Lyme disease cases in the U.S.
“Now, Caitlin, you mentioned Lyme being the most common and probably familiar tick-borne illness, but what are some of the others?”
Preventing Tick Bites
21:41 to 24:25
Strategies and tips for protecting yourself from tick bites.
“Many of us plan to spend a lot of time outside.”
Protecting Pets from Ticks
24:25 to 26:40
Discussion about tick prevention and treatment for pets.
“DEET has over 70 years of data demonstrating safety and effectiveness.”
Vaccines for Ticks and Lyme Disease
26:40 to 28:00
Exploration of Lyme disease vaccines and public interest.
“Bobbi Pritt, also with us epidemiologist, Caitlin Jettelina.”
Understanding Lyme Disease Vaccines and Symptoms
28:00 to 32:12
Learn about the development of Lyme disease vaccines and how to identify symptoms.
“Is there anything similar in development for humans?”
Personal Stories of Lyme Disease Diagnosis
32:12 to 33:00
Hear personal accounts of the challenges in diagnosing Lyme disease.
“How many third-party vendors does your company use?”
Preventing and Treating Lyme Disease
33:47 to 42:00
Discuss effective prevention methods and treatment options for Lyme disease.
“Let's get back to ticks and the diseases they carry.”
Navigating Alternative Treatments
42:00 to 42:34
Learn how to choose reputable medical advice regarding alternative treatments.
“nonstandard tests and inappropriate alternatives to FDA and IDSA approved methods.”
Understanding Tick-Borne Illnesses
42:34 to 44:11
Discover the importance of reliable resources for information on tick-borne diseases.
“Yes, I think it's important to really use reputable physicians that have experience in this area, going to places that are backed in science and following guidelines that are really backed in science.”
Introduction to Alpha-Gal Syndrome
44:11 to 45:26
Explore the nature and causes of alpha-gal syndrome and its impact on individuals.
“Even after seven years, I still have to wonder whether a food, medication or unexpected exposure could trigger a reaction.”
Challenges of Alpha-Gal Syndrome
45:26 to 47:14
Learn about the challenges and treatment options related to alpha-gal syndrome.
“At this point, it's treatable, but the treatment involves avoiding any type of meat that could have this alpha-gal protein, which would be any type of non-primate mammalian meat.”
Assessing Tick-Borne Illness Risks
47:14 to 48:26
Understand the risks associated with tick bites and the measures to take.
“I mean, Caitlin, how concerned should people be right now about tick-borne illness?”
Expert Recommendations on Tick Prevention
48:26 to 48:56
Get insights from experts on how to prevent tick bites while enjoying outdoor activities.
“Yeah, I would agree with everything Caitlin just said.”
Transcript
Automatic transcript. May contain errors.0:00You know, every day on Up First, NPR's Golden Globe-nominated morning news podcast, we bring you three essential stories. At the heart of each story are questions. What really happened? What really mattered? What happens next? At NPR, we stand for your right to be curious and to follow the facts. Follow Up First wherever you get your podcasts and start your day knowing what matters and why.
0:31In 1966, the United States declared victory over a destructive, flesh-eating parasite that devastated livestock. The New World screwworm is a fly whose larvae burrow into the living flesh of mammals. It was eradicated after a long campaign that involved releasing millions of sterile flies over infested areas. Last week, the new world screw worm came back. The U.S. Department of Agriculture confirmed five cases in Texas and New Mexico, three calves, a goat, and a dog. These are the first cases in the food supply in decades. Federal officials say the meat supply is safe, but the cattle industry is on high alert.
1:09The U.S. cattle herd is already at a 75-year low, beef prices are high, and a screw worm outbreak could make it worse. Later in the show, will turn to another critter wreaking havoc, ticks. The population is growing and spreading across the U.S., including in areas that haven't had to deal with ticks before. Emergency room visits for tick bites hit a 10-year high in April for that time of the year. And a growing number of Americans are discovering they've developed an allergy to red meat triggered by a tick bite. I'm Jen White. You're listening to the 1A Podcast. We'll get to that and more right after this short break.
1:44Stay with us.
1:49This message comes from Vanta. How many third-party vendors does your company use? 20? 200? Thanks to AI, someone on your team probably added three more this week, and your security lead has no idea. Traditional third-party risk management can't keep up. Vanta gives you continuous coverage across every vendor automatically so you actually know what's in your stack and what to do about it. AI on, risk off. Vanta.com slash TPRM. This message comes from NPR sponsor, NetSuite. Every business is asking the same question. How did they make AI work for them? With NetSuite by Oracle, you can put AI to work today.
2:31NetSuite is the number one AI cloud ERP, trusted by over 43 ,000 businesses. It's the unified suite that brings your financials, inventory, commerce, HR, and CRM together. If your revenues are at least in the seven figures, get the free business guide, Demystifying AI, at netsuite.com slash story. Each story you hear on Planet Money starts with a question. What happens if we refund tariffs? Why are groceries so expensive? At NPR, we stand for your right to be curious, because the forces shaping our world can be hard to see. Follow NPR's Planet Money wherever you get your podcasts and start seeing how the economy really works.
3:18Welcome back to the 1A podcast. We're talking screwworms and ticks today. And let's start with the screwworm outbreak. Here to talk about the risks and what the government is doing about it is reporter Leah Douglas. She covers agriculture and energy for Reuters and has been following the outbreak. Leah, welcome back to the show. So much for having me. And Caitlin Jettelina is an epidemiologist, scientific communicator, and author of the Your Local Epidemiologist Substack. Caitlin, great to have you with us. Thank you for having me. So Leah, first, tell us more about the New World Screwworm. What is it?
3:53New World Screwworm is a bit of a misnomer. It's actually a fly, not a worm. It's a parasitic fly, and the screwworm can infest any warm-blooded animal. So you said mammals, that includes livestock, but also pets, wildlife, and in some rare cases, people. Now, five cases were recently detected in the U.S. This hasn't been seen in decades. What's the risk of further spread? The experts that I've spoken to have said that they do expect the screwworm fly to continue to spread. As you said, this was a pest that was eradicated from the U.S. in the 60s and really pushed really far south through Central America all the way to the Darien Gap through a collaborative effort between the U.S.
4:39and Mexico and Central American countries. And it's been encroaching further northward for the last several years. And now that it's crossed into Texas, there is an expectation that it will continue to spread. However, there are treatments and the federal government is pouring resources into this, which I'm sure we'll discuss too. Caitlin, what do symptoms look like for animals and for people? Yeah, this is an incredibly painful experience. Like the previous speaker said, this is where eggs hatch into tissue and further burrow into. And it's exactly as bad as it sounds. and the living flesh really hurts and it smells a lot and it is fatal if it's untreated.
5:26What's the treatment for the parasite? It really is a combination of things there. This is one of those moments where ivermectin, I don't know if you guys remember that from COVID, can be used for animals. the effectiveness among humans is unclear, but it does remain on off-label use, and there is positive anecdotal evidence for human use as well. Now, the reappearance of screwworm in the U.S. wasn't a surprise to the Department of Agriculture and people in the cattle industry. We got this message from Tom Patterson. He's president of the New Mexico Cattle Growers Association. This is something we've known was coming for the past 12 to 18 months.
6:12The only question was when it would happen, and now we have that answer. Aaliyah, what is the government doing to try to contain the outbreak? Well, I've heard exactly that sentiment from so many people I've spoken to, whether they're along the Texas-New Mexico border or working in the federal agencies. The administration has been working for at least a year to try to stand up preparation for what was really seen as an inevitability that the screwworm would cross into the U.S. They've surged personnel from the USDA to southern Texas. There's been efforts between animal health drug makers and the federal government to build a stockpile of treatments.
6:52The Food and Drug Administration has issued about a dozen emergency use authorizations to enable fast tracking of treatments that can be used in pets and livestock. So it has been a multi-agency public-private effort over the last year that now is being put to the test by this growing number of cases. There's been a lot of finger pointing about who exactly is to blame for the parasites reintroduction into the U.S. Here's Secretary of Agriculture Brooke Rollins at a press conference in Texas on Monday. We have been prepared and preparing since early last year for the reemergence in America. Now, this does trace back to the last administration and the open border policy and the movement of millions of people and their animals up through from South America through Central America.
7:44Now, Leah, we hear there Rollins putting responsibility on the Biden administration, but what do we know about how the fly came back to the U.S.? Certainly, livestock movement is a significant factor there. There's been some reporting and some discussion that perhaps illegal movement of livestock across, you know, sort of circumventing the procedures that were trying to keep pests like this suppressed in Central America and in Mexico perhaps contributed to the spread. The Biden administration was working on screw worm in the sort of months before the administration ended. The pest started moving north about 2022, 2023.
8:28And so there were efforts under the last administration to start preparing. At the time, it was still in far southern Mexico, so it wasn't nearly at the urgency level that it's become under this administration. So there has been finger pointing, and the government of Mexico has rebuffed some of the Department of Agriculture's blame southward for the spread. Well, it's also important to note that under DOGE, the Animal and Plant Health Inspection Service in the USDA lost employees as part of the cuts to the federal workforce. But the Trump administration also made cuts at the USDA, and some of the programs targeted were monitoring and responding to the New World screwworms.
9:14So has that played a role in this resurgence? So the Animal and Plant Health Inspection Service, which is the arm of the USDA that manages animal disease outbreaks, saw about a 25 percent attrition of staff last year between normal attrition, but primarily people who are taking some of the buyouts that were led by DOGE. And the administration has said that, or Brooke Rollins has said, that there's been no impact. She said zero impact on the screwworm response from those cuts. However, Democratic senators and some veterinarians, some ranchers in Texas are concerned about the quality of the USDA response and have raised the specter of these staff departures as a potential risk as the outbreak continues.
10:03We got this question from Will who asks, what is the difference between screwworms and blowflies? Does North America also need to worry about blowflies? Caitlin, what can you tell us? Screwworms are a type of blowflies. They are part of the same family and not as fatal or impactful as the cousins, but they are related. and something for us epidemiologists continue to keep an eye on. Well, let's turn back to Tom Patterson of the New Mexico Cattle Growers Association. This is what he says he's doing on his ranch to monitor livestock. We pay attention to wounds, irritated behavior, animals that are separating themselves from the herd, loss of appetite, head shaking, unusual odors, or the presence of maggots in a wound.
10:56If possible, and sometimes it's not possible, We're going to be postponing elective procedures to create open wounds until we know more about the extent of the situation. Leah, you've been talking to ranchers. What are they telling you about the potential impact on the cattle industry and the meat supply? Well, the USDA has estimated that a widespread outbreak of screwworm in Texas could cost the industry there about$1.8 billion. in terms of some factors that could contribute to that are the costs associated with that heightened monitoring that was just described, the administering of treatments, the veterinary care, and so on.
11:35So there is a potential economic impact to the livestock industry. And we also know if you're shopping for beef in the grocery store, prices of beef have been very high. That's been contributed to in part by the border closure between the U.S. and Mexico. The U.S. has not been importing cattle from Mexico as one of the measures to keep screwworm at bay. So there also could be a consumer impact down the line of potentially even higher beef prices. Well, Caitlin, just to be clear, because I'm sure people who eat beef right now are wondering, is it safe to eat beef? It is. Beef is safe to eat. This is one of the main reasons.
12:14I mean, there's two main reasons. One, if the animal dies, the larvae basically abandon ship. And so So there's that. If the cows are infected, the meat is no good, and so they aren't slaughtered. And this is why this parasite is just so problematic, right? When cattle are infected, both the meat and the hide are damaged and considered a loss to the rancher. Well, that's Caitlin Jettelina. She's an epidemiologist and scientific communicator. She found at the Substack, your local epidemiologist. She's staying with us to talk about another parasite, ticks. Also with us today, reporter Leah Douglas.
12:51She covers agriculture and energy for Reuters. Leah, thanks for joining us. So much for having me. And just a quick clarification. We got an earlier question about blowflies. The common blowfly feeds exclusively on decaying flesh, while screwworms eat living flesh and healthy tissue. Just an important note there. We'll be right back.
13:13This message comes from Vanta. How many third-party vendors does your company use? 20? 200? Thanks to AI, someone on your team probably added three more this week, and your security lead has no idea. Traditional third-party risk management can't keep up. Vanta gives you continuous coverage across every vendor automatically, so you actually know what's in your stack and what to do about it. AI on, risk off. Vanta.com slash TPRM. This message comes from NPR sponsor, NetSuite. Every business is asking the same question. How did they make AI work for them? With NetSuite by Oracle, you can put AI to work today.
13:54NetSuite is the number one AI cloud ERP, trusted by over 43 ,000 businesses. It's the unified suite that brings your financials, inventory, commerce, HR, and CRM together. If your revenues are at least in the seven figures, get the free business guide, Demystifying AI, at netsuite.com slash story. On Consider This, NPR's afternoon news podcast, we cover everything from politics to the economy to the world. But every story starts with a question. At NPR, we stand for your right to be curious, to make sense of the biggest story of the day and what it means for you. Follow Consider This wherever you get your podcasts.
15:05Experience is getting more common as the U.S. tick population grows and spreads. Ticks are responsible for spreading roughly 90 % of all vector-borne diseases in the U.S. Lyme disease is the most common, but other infections are on the rise too, like the tick bite-induced meat allergy called alpha-gal syndrome. And just to add insult to injury, a tiny tick bite can even attract a screw worm looking for a spot to lay its destructive eggs. So how can you protect yourself, and what should you do if you are bitten by a tick? Caitlin Jettelina is still with us. She's an epidemiologist and scientific communicator.
15:41She writes the Substack, your local epidemiologist. And joining us now is pathologist Dr. Bobbi Pritt. She chairs the Mayo Clinic's Division of Clinical Microbiology, where she specializes in parasitic and vector-borne infections. She's also helped discover two new tick-borne pathogens, including one that causes Lyme disease. Dr. Print, welcome to 1A. Thank you for having me. So April is the start of tick season, and this year emergency room visits for tick bites were higher than in the 10 previous Aprils. Why are we seeing this increase? Well, I think that the ticks are out and biting, and with the earlier start to our spring, the ticks started coming out as soon as the ground thaws and the snow melts.
16:24And now we're having people with the increased awareness of tick bites getting exposed to ticks and realizing that they could pose a significant health threat to them. So they're going to their health care providers. So you said these ticks could pose a threat to their health. Are we seeing a corresponding increase in tick-borne disease? Well, we are, yes. And actually, if you look at cases of tick-borne diseases in the United States, they've more than doubled since 2004. Every year, they continue to go up. Caitlin, what are the most common diseases ticks carry? The most common, I mean, so there's over 900 species of ticks, but only about 20 tick-borne diseases.
17:06So not every tick you encounter will give you a disease. I think that's important to know. But the most common tick-borne disease is Lyme disease. It's this bacterial infection transmitted by two species of ticks in the United States. And it's most common because this black legged tick has a relatively broad distribution. And this bacteria that it can carry has well - established populations, mainly in white-footed mice, as well as white-tailed deer reservoirs. So you said two species of ticks carry Lyme disease and the long-footed tick was one of them? One of them is the black legged tick. Black legged tick.
17:50And what's the other? Sure. It is, I'm actually not entirely sure. Dr. Pritt, any insight there? Yeah, I can jump in. It's the western black-legged tick Ixodes pacificus, which is found on the west coast versus the one that we know in the northeast and the upper midwest, which is Ixodes scapularis. They're cousins. Is there anything distinctive about these ticks that might help someone identify them, Dr. Parade, if they find one? Yeah, well, they're pretty small. But one thing to keep in mind is that as they start feeding on you, as disgusting as that sounds, they're drinking your blood and they get larger and they can be quite large.
18:30But the tiny size when they first bite you can be very challenging. In fact, the nymphal tick is the size of a poppy seed. and then even the adult ticks are only about the size of a sesame seed. So I think that's significant to know when people are checking themselves for ticks. They might think of what we call the dog tick dermis center, which is a little larger, but you really have to look for those tiny little specks like you said in your opening. Well, ticks and the diseases they carry are showing up in parts of the country where people didn't previously really worry about them. For example, the lone star tick, which was primarily found in the South, In recent years, it's shown up in the Northeast and in the Great Lakes.
19:12Why are we seeing ticks in new places, Dr. Pritt? Well, part of it is just their natural expansion, and they can be carried by migratory birds. They can be carried on deer. But then also the weather is supportive of their continued expansion. Ticks do well when it's warm and humid. They don't do so well in the dry areas, so there may be some parts down south where we'll see less ticks in the future. But in the north, we know that our winters have been milder. And with that climate change, those aggressive Lone Star ticks are more able to survive our winters. In fact, we now know the Lone Star ticks are established in Wisconsin.
19:50They're coming up into Minnesota, where I live, and we have very harsh winters. And they're all up the northern seed board right up into New England. Now, Caitlin, you mentioned Lyme being the most common and probably familiar tick-borne illness, but what are some of the others? Yeah, I mean, I think one of the most fatal tick-borne diseases is the U.S. Rocky Mountain spotted fever, but it is rare, so that's good news. Between 250 and 6 ,000 cases occur in the United States every year, but the mortality rate is high, up to 30 % without prompt treatment. This one usually occurs in five states, North Carolina, Tennessee, Oklahoma, Arkansas, and Missouri.
20:38But again, I think you said it earlier, one of the most talked about tick-borne diseases beyond Lyme disease is the alpha-gal syndrome. And we'll talk more about that in a moment. Dr. Britt, Health and Human Services Secretary Robert F. Kennedy Jr. announced a multi-million dollar plan to tackle Lyme and tick-borne illnesses. Tell us about those initiatives. Sure, I'd be happy to. I was involved in some of the earlier initiatives back in 2020 to 2022. This is a new initiative now, though, where there is a national goal of reducing Lyme disease by 25 % by 2023. So less than 10 years to go now. And there have been some important new investments in tick control research, next generation diagnostics, which is what I do, is the diagnosis of Lyme disease, additional findings for research on alpha-gal syndrome.
21:28And I think what's nice to know is there's a real focus on patient care, public awareness, and also some of the ongoing symptoms that people experience with Lyme disease after they've been treated, but continue to have ongoing health symptoms. Well, Caitlin, it is summer. We're in peak season. Many of us plan to spend a lot of time outside. What's the best way to protect ourselves? Yes, and we should be spending time outside. It brings so much joy. And the great thing is that we can implement multiple layers to prevent tick bites. And if we prevent tick bites, we prevent the risk of illness. And set aside on clothing really helps.
22:09Put it on shoes and pants. Effective repellents like DEET protect for about six to eight hours. Other things like light colored clothing and pants tucked into socks improve the visibility of crawling ticks on clothing. And once you're done going outside, check for ticks, right? Ticks climb up your body seeking really a suitable feeding site, right? Warm, moist, protective spots. It can take 15 minutes to hours for them to really select a location like your groin or armpits or behind the ear. So be sure to check all crevices before spending time outdoors. Also other tips, shower. After being in these tick habitats within two hours, it helps wash off these crawling things.
22:59And then remove ticks promptly if you see one. I think that most pathogens can be transmitted if a tick feeds for a certain duration. So like mechanical remover, like literally using tweezers is really the only recommended method. And you talked about areas where ticks may be more present. Are there places we should maybe avoid or be particularly cautious if we visit them? I mean, across the United States, the most Lyme disease is up in the Northeast, although we are starting to see it spread more and more. And in the environment, it's tall grass. These boogers step on tall grass, and they can easily jump to us while we're hiking or while we're out in the outside.
23:50And just a quick clarification. Ticks don't literally jump. They also don't fly. They climb onto grass or bushes or leaves, and then they latch on when an animal or a person brushes by. They then crawl around and find a suitable feeding spot. Now, there are a lot of products out on the market. There are also natural and homemade insect repellents. Caitlin, what's a baseline that we should look for if we're searching for a repellent that will work against a tick? I mean, really look for DEET, right? There's a lot of natural, or like you said, homemade tick repellents, and they're not necessarily safer or more effective.
24:25DEET has over 70 years of data demonstrating safety and effectiveness. These essential oil-based repellents are ineffective and also can be dangerous, especially for young children and pets. Well, it's not just humans who are susceptible to tick-borne disease. We've heard from several of you about your pets. Barbie in Indiana left us this voicemail. When we were kids back in the 70s, we had a bunch of dogs and cats outside because we had a farm. We hardly ever had ticks on them. And if we did, we just picked them off. We didn't have flea collars and tick collars and none of that stuff. Now it's unheard of.
25:07You cannot leave your dog without protection because they'd be loaded with ticks. And Wendy lives in the Catskill Mountains of New York. I have had many ticks on me, and I have had Lyme previously. But what I'm really concerned about are my dogs because they are always picking up ticks. My worry is that the flea and tick medication that's available is just not working because my animals get that every month, yet they continually contract Lyme disease from tick bites. Barbie, Wendy, thanks for those messages. Dr. Pritt, what do we know about the protections available for animals? Do they work? Well, they do when they're used properly.
25:52And thankfully, there are a number of different things we can do for our pets. As we were just talking about, prevention is still the best defense, preventing those tick bites to begin with. But, well, let's just talk about dogs. They probably have the best established protections. They have the oral medications, the topical products, the tick colors. They also have a Lyme disease vaccine for dogs, which is highly effective. So all of those things are important in protecting your pets. I'll also add, though, that pets are also an important method of bringing ticks into the household. And so as we were discussing, checking yourself for ticks when you come inside after being outdoors, don't forget to check your pets too because they could bring ticks into the house.
26:36Even if the ticks aren't biting them, they could then bite you. We're speaking to Mayo Clinic pathologist, Dr. Bobbi Pritt, also with us epidemiologist, Caitlin Jettelina. I'm Jen White. You're listening to 1A. Dr. Pritt, you mentioned a Lyme vaccine for dogs. Why isn't there one for humans too? Well, it's interesting you say that. There used to be a Lyme disease vaccine, but at the time it wasn't the risk. Lyme disease was not the risk it is today. And there just wasn't a large demand for it. So it was pulled from the market, not because it wasn't efficacious, but just because it was low sales and poor public acceptance.
27:16And so do you see now with this higher presence of ticks that that might come back on the market, that there may be increased demand for it? Yes, so there actually are a number of organizations working on Lyme vaccine. The Pfizer-Valneva vaccine is probably the furthest along. They recently reported their phase three trial results, which showed about a 75 % efficacy against Lyme disease. And they are planning to submit the vaccine to the regulatory authorities soon. So I think we should keep our eye out on what's going on with Lyme disease vaccines. there hopefully will be something available in the coming years.
Read the full transcript
27:57Well, we got this question from Jill who says, we give our dog a preventative pill for ticks. Is there anything similar in development for humans? Dr. Prent, I'm coming back to you on that one. Yeah, there's not really a preventative pill that would probably be widely accepted by humans. I think we're more used to vaccines and preventing disease. And as I mentioned, there are some vaccines, one that's actually quite along and there are others as well that hopefully will be on the market in the coming years. So I think probably what we'll be looking at is people that are at risk of Lyme disease, people that go outdoors often, people that live in highly endemic Lyme disease areas should really consider getting this Lyme disease vaccine when it becomes available.
28:39Okay, Lynn, if you do find a tick on your body, what should you do beyond removing it? What should you do? Yeah, you remove it. Like I said, most, well, first of all, most ticks do not cause disease, but if, you know, remove it nonetheless. And it must feed for a certain duration. So use those tweezers. But then look out for symptoms, too, in, you know, the next few hours to a day or two. And then if you do have symptoms and you think it may be due to a tick, call your physician. Now, the CDC says only 70 to 80 percent of people infected with Lyme disease will get that telltale bullseye rash around a tick bite.
29:27So, Dr. Print, what else should people watch for? Well, there are a number of other symptoms and signs that may be present with Lyme disease. For example, people early on may have a little bit of a fever, fatigue, headache, muscle aches and joints. but as we were just saying, the bullseye rash is not always present or it may be in a part of the body where people may not see like on their scalp or their back. So really anytime that someone feels like they just have these symptoms and they've been potentially outdoors exposed to ticks, it's a good sign to go to your healthcare provider and mention that you've potentially had tick exposure.
30:07And what about symptoms in dogs, Dr. Pritt? How might symptoms of Lyme disease present in them? Well, dogs are a little different because they can't tell you if they're feeling tired or have muscle aches and pains, but the way that they act can be observed usually by their owners if they aren't as energetic, they don't appear to be as agile when they're playing. Usually it's a little bit more subtle in pets though. And is there a benefit to saving a tick that you've removed from your skin or from your animal? I recommend saving it if it's been attached for a while and it's engorged. And there are actually some areas of the country where there's a lot of Lyme disease where if you find an engorged tick on your body, that would be indication to go to your healthcare provider.
30:54Bring the tick. You can get it identified. And if it's identified as a black-legged tick, in certain circumstances, is the healthcare provider could actually give a dose of an antibiotic called doxycycline to prevent Lyme disease. But that's only if the tick's been attached for 36 hours or more, or it's very visibly engorged, meaning it's been there for long enough to transmit Lyme disease. We're discussing ticks and the growing risk of tick-borne disease. We're here with Dr. Bobby Pritt, a pathologist and clinical microbiologist at the Mayo Clinic specializing in parasitic and tick-borne infections.
31:28Also with us, epidemiologist and scientific communicator, Caitlin Gentilina. Kristen emailed us about her long journey to a Lyme diagnosis. I saw 13 doctors and none of them believed my symptoms were real or thought they were relevant. I was told I was just stressed out and that I could use to lose some weight. After 18 months of this, I was losing the ability to walk and couldn't remember the steps to make coffee. I decided to use my remaining mental and physical resources to find a medical practice that took on hard cases. I got a diagnosis, active Lyme disease. The whole system is blind to Lyme disease and associates it only with tick bites and bullseye rashes.
32:05I hadn't had a tick bite in decades and never got a rash. Well, when we come back, we'll have more on Lyme disease and alpha-gal syndrome. We'll be right back.
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33:47Let's get back to ticks and the diseases they carry. We got this email from Mary who says, I live in an area where deer are prevalent. I have loved watching them. I have fenced off an area for my dog. I have socks treated with an insecticide, but I am still afraid of walking through my yard and my dog around the neighborhood. Dr. Print, I mean, how concerned does Mary need to be about taking the dog on a walk or just walking through a yard that has a mowed lawn? Well, the mowed lawn will definitely help her. and the fact that it's fenced off keeping the deer out is also going to be helpful. But if there are deer around and tall grasses, there is a potential that ticks could get into her yard.
34:28But it seems like she's doing the right things. I think it's always a balance. You want to be able to go out and enjoy the great outdoors and do the things you enjoy. But then understanding that there is this risk from tick bites, I would say to her to continue doing all the great things she's doing but not stop living life. and also using those additional methods such as checking for ticks when she comes in from outdoors. And hopefully that would be a good balance for her to still be able to get outdoors. Well, we've also had several people write in to ask about the use of permethrin to treat clothing.
35:04And Caitlin, can you tell us about whether permethrin is a useful tool in treating clothing if you're trying to avoid ticks? I believe it's an insecticide of some sort. Yeah, it is effective. It kills ticks upon contact. And it is best to apply those to shoes and pants. You must let it dry fully, but it can last for several washes once you put it on. So it is a great use for prevention. So Dr. Pritt, how important is it to be treated and tested quickly for Lyme disease? or I should say that in the other direction, test it and then treat it quickly for Lyme disease. If you have a bite, if you start to have symptoms, how much does the timing matter?
35:52It is quite important to get seen by your health care provider and then get treated. We know that the risk of having dissemination of Lyme disease goes up if you're not treated early. So if someone is potentially going to have Lyme disease, they should be seen by their health care provider. Certainly, if they have a bullseye rash, which is the classic sign, they should go to the physician and be treated for Lyme disease because in Lyme endemic areas, that is diagnostic of Lyme disease. There are also other complications that can occur if you're not treated early. So early senior health care provider, early diagnosis, and early treatment are all keys to helping to protect people.
36:35But we've heard from several listeners about having difficulty getting diagnoses, especially early on, Dr. Pritt. Why is that? Well, I think it depends on where you are in the country. There are some areas that don't have as much Lyme disease as others. There are some physicians and health care providers that may not be familiar with all of the recommendations for preventative measures and for treatment of Lyme disease. So I think people will have different experiences based on where they've gone to. In endemic areas, it's usually easy to find someone who's well-versed in Lyme disease prevention and treatment.
37:11But unfortunately, everyone's experiences can differ a little. Caitlin, what is the treatment for Lyme disease? You mentioned antibiotics early on. Yeah, that's right. And of treating the symptoms. I think that the question, though, around chronic Lyme disease is a bit different. And that's when those who report symptoms long past taking those antibiotics and getting bit by a tick with Lyme. And we'll talk more about that in just a moment. But we first got this question from Mike in DC who asks, is it true that Lyme disease can lie dormant for years, Dr. Pritt? There really isn't evidence that someone who's been treated for Lyme disease will have persistent infection.
37:57But it is true. If someone has Lyme disease and they were never treated, then yes, the bacteria can stay in your body. And in a significant number of people, it will actually disseminate in about 60 % of cases from that initial bite to other parts in the body, including other areas of the skin, the joints, the nerve, the heart, the eyes, even the brain. And so that gets back to your previous question about why prompt treatment is so important. And tell us more about some of those symptoms that people may experience if the disease lingers in their bodies. Well, some of the ones that people would be most familiar with would include arthritis and involvement of the nerves.
38:38Some people will develop Bell's palsy where they will have a paralysis of the side of their face. So one side of their face, they won't be able to smile or close their eye to the same extent as the other. The arthritis is also very serious, and that can be swelling of usually a large joint, like a knee, that can last for years and obviously be very debilitating, difficult to treat as well. Here's a message we got from Jake in Alexandria, Virginia, about his experience with Lyme disease. I was bitten by an infected tick when I was in eighth grade. I got the classic bullseye rash and high fever.
39:20Eventually, my doctor figured out what was wrong, and I got on antibiotics and felt better, but I still attribute some of my ongoing fatigue issues to Lyme disease. There have been a number of studies about maybe long-term impact of Lyme disease, and that's an area that I hope continues to get studies and research. Thanks for that message. Caitlin, there is some controversy around the idea of chronic Lyme disease. Tell us more. Yeah, I mean, first of all, I just want to say, you know, chronic Lyme disease or having symptoms for a long time is incredibly frustrating. It can be very debilitating and just full of awfulness.
40:04Some doctors call this chronic Lyme disease, The CDC calls it post-treatment Lyme disease syndrome, but it doesn't have a clear conclusive answer or really diagnosis. And the answer is we don't really know what's causing this. We don't have good evidence that it's bacteria still living in the body, which is the assumption kind of baked into the term of chronic Lyme. There is some recent work suggesting that it's not the bacteria that persist, but maybe the components of them that remain and trigger inflammation. but regardless, antibiotics for weeks over weeks over weeks won't get rid of it. And it is a condition that we don't have a lot of answers to.
40:49Sometimes when really properly investigated, some people with this post-treatment Lyme disease syndrome end up having another condition that responds to therapy like fibromalacia or rheumatoid arthritis. but we still have a lot of unanswered questions like that caller mentioned. We still need a lot of work into this area. Well, here's another question we got from Christine who says, I've had a few friends whose lives were destroyed by Lyme disease. There's a common understanding in our community that it can be sexually transmitted. Is that true? Dr. Pritt? Yes. There's no evidence at this point that this is a sexually transmitted disease.
41:29It certainly would not be the predominant means. It's really linked to that tick bite. Well, as the number of Lyme cases rises, the market for treatment is growing, but not all treatments are backed by science. Caitlin, what can you tell us about this boom in alternative tests and treatments for Lyme disease? Well, it's kind of what we're seeing across the board, not just with Lyme disease, but a lot of people desperate for solutions in the wellness industry coming in, not only for treatments or natural like tick repellents or prevention, but also nonstandard tests and inappropriate alternatives to FDA and IDSA approved methods.
42:15And there's just this complex network of fraudulent and people taking advantage of a lot of this fear, as well as suffering that some of these patients are having. So Dr. Pritt, what do you want people to know or think about before they consider pursuing alternative treatments? Yes, I think it's important to really use reputable physicians that have experience in this area, going to places that are backed in science and following guidelines that are really backed in science. As a scientist myself and a physician that cares for patients, those are really important things I would look for. And Caitlin, what about you?
42:57Yeah, I mean, I agree, you know, but it's really hard, especially online, to know who is reputable and who is not. And it's really challenging to know where to turn to if you don't have a regular provider. And so some information, places to go get information, you know, the CDC website, I will say, has been tainted in some places like vaccines. but I still do trust the tick section. And on that website, you have tick species by region, disease risk and prevention. State health department pages also have a lot of information for your specific area and what ticks you may specifically encounter, as well as there's some, you know, nature and wildlife resources too.
43:44But number one is to try to find a reputable scientist or a physician, and then go to some of these resources. Well, as we just heard there, not all tick-borne illnesses are from pathogens as Lyme diseases. Alpha-gal syndrome is an allergy to red meat and dairy. It's triggered by tick bites and it's on the rise. Debbie Nichols and Candice Mathis told us they've been living with the condition since 2019. Even after seven years, I still have to wonder whether a food, medication or unexpected exposure could trigger a reaction. Last year alone, I used 11 epi auto-injectors. And because one isn't always enough, I typically carry at least three with me everywhere I go.
44:28People really have to become their own detective, their own advocate. They have to research ingredients to make sure that they're safe. And this is also a burden on their loved ones as well. So it's a huge learning curve. Debbie and Candice run a blog called Two Alpha Gals, where they share tips and tricks for living with a condition. Caitlin, what causes alpha-gal syndrome? It's really quite interesting. Like you said, it's not an infection, but it's an allergy. So after feeding on mammal blood, this lone star tick carries this sugar molecule called alpha-gal in its gut. And when it bites a person, there's really small trace amounts of that sugar that slip into the body through its saliva.
45:11And because humans don't naturally carry alpha-gal, our immune system sometimes, and what we're seeing with these alpha-gals, is treat it as foreign and start making antibodies against it. And later, when that same person eats red meat or other animal products, the immune system recognizes that alpha-gal again, and it triggers this allergic reaction, often several hours after a meal. Dr. Pritt, is this a curable condition? Well, unfortunately, no. At this point, it's treatable, but the treatment involves avoiding any type of meat that could have this alpha-gal protein, which would be any type of non-primate mammalian meat.
45:56Thankfully, it does not include fish or birds, but still, as we just heard from the person who had called in, you have to wait for many, many years before the level of these antibodies against alpha-gal go down so that you can safely eat meat again. Well, we got this from Laura, who emails, this area is experiencing an upsurge in tick bites. Both our pharmacists and primary providers have stated it is increased in our area. We need a vaccine. With climate warming, more and more people will be exposed to Lyme and other tick-borne diseases. It is a ticking time bomb. Where's the sense of urgency in the medical community about this?
46:32Dr. Pritt, you're working in this area of research. What are your colleagues saying about it? Where are you seeing new research being done? Well, for alpha-gal syndrome, we have testing, but it's really just test detecting the antibodies to alpha-gal, people that develop this allergy. It's really more in the immunology field. Unfortunately, we don't have a vaccine for it because it's sort of like an allergy, the way people have allergic reactions to other types of things, except it's more of a delayed response. So in this area, there's not really any groundbreaking research yet. And other areas, though, of course, we have significant improvements in testing in the pipeline.
47:12Well, we're hearing from lots of people who are saying they're either scared or grossed out. I mean, Caitlin, how concerned should people be right now about tick-borne illness? I think it's really important, and I've said this a few times, is that just having a— just not every tick you encounter will give you a disease. and that's because several things need to fall into place, right? It needs to be the right species of tick. It needs to have the right pathogen inside that tick. It has to have the right bite, right? It takes a minimum attachment time. And the immune system also just doesn't clear it before it causes illness.
47:52And so, like the other speaker said, ticks are not a reason to not go outside. Going outside is an incredible experience and helps with mental health. And in the case of Lyme disease, the risk of illness following a tick bite in an endemic area is low, about 1 % to 5%. So, you know, be vigilant. Understand where the risks lay. Prevent those tick bites, but don't necessarily stop going outside. Dr. Pritt, anything you'd add? Yeah, I would agree with everything Caitlin just said. I would think of tick bite prevention is just something you do as part of your routine day. If you're putting on your sunscreen and you're going outdoors and gardening, put on your tick repellent as well.
48:40Be considered or conscientious of what your environment is and then just enjoy your day. That's Dr. Bobbi Pritt. She's a pathologist and expert in vector-borne diseases at the Mayo Clinic. Also with us, Caitlin Jettelina, an epidemiologist. And you can find her writing on Substack at your local epidemiologist. Caitlin, Dr. Pritt, thanks for joining us. Today's producer was Claire Mufson. This program comes to you from WAMU, part of American University in Washington, distributed by NPR. I'm Jen White. Nyla Boodoo is with you tomorrow for the Friday News Roundup. Hope you tune in. Thanks for listening, and we'll talk more soon.
49:19This is 1A.
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From the publisher
Last week, that fly came back.
The U.S. Department of Agriculture confirmed five cases of larvae contamination in Texas and New Mexico – the first detections in decades. Federal officials say the food supply is safe, but the cattle industry is on high alert. The American cattle supply is already at a 75-year low. Beef prices are high. And a screwworm outbreak could make it worse.
Outside farms and ranches, the tick population is growing and spreading in new parts of the country. Emergency room visits for tick bites hit a 10-year seasonal high in April. And a growing number of Americans are discovering they’ve developed an allergy to red meat triggered by tick bites.
We sit down with a panel of experts to talk about it.
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