865. The Truth About Aging, Stress + Your Body’s Warning Signs with Dr. Cabral

20:58And the problem is, is that on the exterior, we get to see the symptoms of aging, but we don't necessarily look inside. So if we, now there's a test that we can run called the minerals and metals test. And the reason I mentioned that specifically is because it looks at calcium and magnesium. So especially for women, you are losing bone mass after the age of 27. You're losing muscle mass after the age of 27. So sarcopenia, osteopenia begin very slowly. Remember We always say disease is a destination. It takes years and decades to get there. Alzheimer's is 20 to 30 years. Heart disease is 20 to 30 years.

21:34So these don't happen overnight and we can test for them early, but it's the same with aging. So here's the nice thing. They can be reversed as well. We can talk about the reversal of Alzheimer's if caught early enough. But with the minerals and metals test, we're looking calcium, magnesium, right? Needed for the nervous system, needed for bones. Looks at sodium, potassium, needed for energy in the adrenals. Then we're looking at very specific minerals based on aging, and that is selenium needed for, it's an anti-cancer antioxidant. It's used for the thyroid, really powerful there as well because you can't convert T4 to T3 for the thyroid without selenium.

22:08You need selenium for great hair, skin, and nails. Then there's copper and zinc. Copper and zinc are directly attributed to loss of hair pigmentation. for the strength of the skin, hair, and nails always goes back to copper and zinc, and they can be out of balance. So for example, probably I would say two out of 10 people, it's about 20 % of people are what we call copper toxic, or they have higher levels of copper than zinc. And when this happens, there's higher levels of anxiety, higher levels of rosacea and skin rashes, higher levels of autoimmune-based conditions, learning disabilities in children, and allergies.

22:48Lindsey Simcik:How would someone be copper toxic? Like, are they eating something? What are they being exposed to? We find that it's not often exposure to excess copper, although it can be. There's nothing actually wrong with cooking in copper pans, keeping a copper basin for water, if you're deficient in zinc. But if you're deficient in zinc, that's when it becomes an issue. So we actually, everything is a ratio. So let me give you another example. When we look at calcium to magnesium, everybody talks about magnesium, but we need a lot of calcium. We need to get it from our diet. but the proper ratio is about a six to one when we look at zinc to copper it's a 15 to 1 so it's a it's a massive amount more of zinc to copper okay so if you were to look at let's say a multivitamin you would see 15 milligrams of zinc to about one milligram of copper you don't want a lot of copper in your diet or in your vitamins but the problem is why do we go through zinc so quickly Whenever we're stressed, we break down three nutrients the fastest.

23:48One is zinc, the other is glutamine, and the other is B vitamins. So we wipe through those. Now, B vitamins are obviously very popular. They're talked about, almost no one's talking about zinc and copper. When you get a virus, it wipes through zinc. Zinc builds up your white blood cells. It's part of your immune system. So it's not that people are taking usually too much copper.

24:06Lindsey Simcik:It's that their zinc levels are depleted, which then allows copper to rise. So there's a yin and yang to everything. if we want someone to reduce calcium in the bloodstream like taking in too much vitamin d we should always take in magnesium because magnesium will pull that calcium then out of the bloodstream when you take uh let's say a vitamin like a high dose vitamin d um when we get if we so if someone has too much copper we just get more zinc it pushes the copper levels down okay because the body competes for these specific nutrients okay can't use them both at once essentially and you supplement with zinc that's your recommendation like is there with With zinc, you can also take things like pepitas or pumpkin seeds or high in zinc.

24:43There's other ways to get zinc. Get zinc from meat, from protein. So all of those great eggs have zinc in them as well.

24:49Lindsey Simcik:Okay. And in nature, nuts, seeds, and oysters, things like that, have a good balance between zinc and copper already in them. Okay, great. Yeah. Fascinating. um also on the aging piece um I feel like like you said people are kind of noticing it's happening earlier you know so like yeah I think around the time excuse me that people become parents or are in early parenthood and it's exhausting and all the things like I guess it's confusing because I think what we're experiencing, we just automatically attribute to, well, I'm not sleeping through the night or, you know, life is crazy. So I guess for those out there that, you know, might be aging a little bit faster than they should be.

25:44Lindsey Simcik:Is there anything glaring that you can kind of differentiate between just kind of like modern life and like being a parent or just being super busy and on all the time and actual accelerated aging. Yes. And so I didn't want to make like minerals to be the only thing, but it's a big part of it. Because we always talk about B12, methylfolate, B9. Now we're starting to talk about hopefully more B6, which is regulating the nervous system. But aging comes down to a lot of it is oxidative stress. That's really the ultimate. So our body is no longer able to keep up with as well the free radical damage inside of the body.

26:21That part of that's mitochondrial. Again, in personomics, I talk about really the 12 pillars of aging. But the easiest way to think about it is that we have too much oxidation inside of the body and now it's showing up on the outside. Now, how does that get accelerated? We're under eating. We're over exercising, many of us, right? So if you think about it, a marathoner looks, usually ages them much faster. Yeah. And the reason is think about the oxidative stress of running 30, 40, 50 miles a week, you know, on average, and hopefully keeping up with it in terms of nutrition, but oftentimes not enough protein, not enough healthy carbs.

26:59We've been told carbohydrates are bad, right? Carbohydrates are the thing that help us sleep better at night, produce more serotonin, relax the central nervous system. So we really need a balance in terms of our nutrition. Some people, of course, need a little less starch. Some need a little bit more. It is based on somewhat body type and energy expenditure. But also sleep is such a huge factor. So if you look at, especially when you have kids, one is you've got another life to care for that's going to automatically be more stressful. So stress is going to increase cortisol levels. It's going to potentially decrease the amount of vitamins, minerals that your body's not able to use, but it needs more now to keep up with the new stress.

27:36And then when you tap into that, not enough sleep, and I'm talking about deep sleep and REM sleep, then the body starts to, again, compensate. so we call this the triage theory on aging there are many different theories on aging and there's not one specific one like stem cell depletion etc but this is really the best one because you can say all right well when i get two weeks of sleep or i go away in vacation i do a retreat i actually look younger oh totally later right it's like yes you've got a little bit more restoration of rejuvenation back in the body and so much of it is nervous system based so this will be like kind of like wrapping it together.

28:12We always blame the hormones or we blame our nutrition, but most of it is neurological. So that means the weight of our emotions, finances, career, family, relationships, that weighs on our inputs, our proprioception of the world itself. That then begins to dysregulate our cortisol levels. Our cortisol levels then dysregulate our sleep, causes estrogen dominance in most women, meaning lowering of progesterone levels that affects your skin as well. And from there, lowers testosterone in both men and women, that decreases ambition and drive, increases anxiety, overwhelm, irritability. And now we find ourselves feeling older.

28:51Well, it started with this load of stress that we haven't been able to deal with properly. So it's not just diet or exercise or supplementation, it's also working on stress.

29:01Lindsey Simcik:Yeah, no, it's such an important piece. And why do you think people write that off why why do people go to the other things first but not to the actual top of the cascade you know we all do yeah and it's because it's easier right it's actually much easier to say okay let me try uh these new goji berries superfood that i read about right or mango supplement or whatever it is exactly whatever the new thing is um rather than saying wow you know every time I run into this problem, I react like this. And then that causes a week of sleeplessness until I resolve that again. And it happens every quarter or whatever it might be.

29:43So instead of tackling the deeper issues, we do look for the easier resolution. And I see that with all clients. I mean, we work with hundreds of thousands of people and that's normal human nature. But at some point we say, while we're working on the other things, which actually helps to stabilize you, right? The diet, exercise, stress reduction, tox removal, rest, emotional balance, scientifically backed supplements, and the mindsets. We call that the de-stress protocol. After we do that and we stabilize, we want to then begin to work on the person themselves. Yes. That's so important.

30:16Lindsey Simcik:I love finding simple swaps that make everyday meals feel a little more supportive of my goals, especially when I don't want to give up the foods I actually enjoy. That's why I have been loving obsessed with Hero Bread. It lets me keep things like sandwiches, wraps, even pasta nights without feeling like I'm sacrificing anything. And I'm at a point right now in pregnancy where I'm not restricting, but I also don't want to be overdoing it on like the gluten and the pastas and all the things. Hero Bread makes it easy and I feel amazing after eating their products. The taste and texture are what surprised me most, honestly.

30:55Lindsey Simcik:Their products are soft, fluffy, honestly feels like traditional bread. I love the tortillas for easy lunch wraps and their sliced bread for quick breakfast sandwiches. I also love their bagels. Every single morning, my son asks for the bagel. He loves them. And then I've been making him the noodles as well. So it really covers all those comfort food staples. I'm excited for you to try. Nutritionally, it fits really seamlessly into my family's routine. Depending on the product, it has zero to five net carbs, zero grams of sugar, and 11 to 32 grams of fiber. It also has protein too. I'm a girl that's been trying to get my protein and my fiber at the same time.

31:33Lindsey Simcik:So I am killing it with Hero Bread. And you really wouldn't know that it is this healthy based on the texture and the taste. So Hero Bread is offering 10 % off your order. Go to hero.co and use the code A30POD at checkout. That's A30POD at H-E-R-O.co. Okay. So lately I've been thinking a lot about how I want to support my body in this season of life, in this kind of like preconception mode, conception mode. And it's a season of life that I've been through before. I have one son. I'm just really intentional about what I'm putting in my body and how I am making sure I'm getting the nutrients that I need.

32:12Lindsey Simcik:So there's so much information out there and it can feel overwhelming trying to make the right choices when it comes to your prenatal. One thing I feel really good about is that in my first pregnancy, I took Ritual's Essential Prenatal. Even if you're just in a phase of preparing your body or being intentional about foundational nutrients, it feels like such a supportive place to start. Their clinically backed Essential Prenatal includes key nutrients like choline, folate, and omega-3. And I love that the ingredients are traceable and thoughtfully sourced. I and a lot of my friends chose Ritual because I really love and trust the level of research behind it.

32:50Lindsey Simcik:It's the only leading prenatal backed by its own human clinical trial, and it was clinically shown to deliver key nutrients like folate, biotin, and vitamin D. I also appreciate that it uses methylated folate and a patented capsule designed to dissolve in the small intestines, which I found makes it really gentle and easy to take, especially I remember that first trimester. It was kind of like a hard thing to wrap my head around that I had to take prenatals, but it made it a lot easier. So compared to other supplements I've tried. It's just been a better overall experience for me. So I highly recommend don't settle for less than evidence-based support.

33:25Lindsey Simcik:Save 25 % on your first month of Ritual at ritual.com slash almost 30. That's ritual.com slash almost 30 for 25 % off your first month.

33:40Lindsey Simcik:The other thing you said that I thought was so interesting was the under eating piece, which I know is kind of like a double click, double click. But I think that despite the talk about like getting enough protein, all, all of these conversations, I do think, especially for women, and I'll just speak from experience of myself in the past and like even just conversations I'm having with friends, that there is kind of still that idea restriction around food if we want to look and feel our best. And I would love for you to kind of talk about this and demystify this and why we must get enough nourishment, nutrients on a daily basis based on our lifestyle, body, you know, body, et cetera.

34:30Lindsey Simcik:And why that is so important for aging, for everything, for disease, all of that. Yes. So, and 70 % of our clients are women and always have been, you know, for the past like 25, 26 years. Women do seem to be more receptive to a lot of wellness-based regimes. And the issue is, and I've given a lot of thought to this because I did start as a personal trainer and nutritionist in the mid-90s to late 90s. and the Atkins diet was still pretty popular and the South Beach diet was gaining popularity. And all of those are really high protein-based diets. They're still deprivation-based diets. And so when we focus on protein, I think we're still unfortunately catering to a lower calorie overall diet.

35:21And I'll kind of come back to that in one moment, but why this matters is that we're always asked, to compensate essentially for our lifestyles. So we'll think of it this way. I always tell clients, you need to think of the energy in, energy out paradigm. So if you are taking care of your kids or working a busy job, not getting the sleep that you should, but you're exercising, you're moving your body, your mind's always active, you're always doing something. Now you say, okay, that's all energy out. What's giving you energy in? Energy in would be breath work, sleep, meditation not cold plunging not even really sauna like sauna is amazing but what are the things that are bringing energy back to your nervous system recentering you and so under eating is just one more energy out stressor because you're if you're just making maintenance or most people are a little bit under your body is then in a metabolic starvation based mode like it's still not there yet so then it has to compensate it needs to compensate by looking for outside sources of energy, which might be dopamine hits.

36:26It might be something like hopping in a cold plunge instead of getting the nutrition and the calories that it needs. So we like to do essentially a reverse diet. We start with wherever they're at right now. We know obviously they don't want to gain weight. So then we say, okay, you're already good with the protein part. You're focused on, let's say 30 grams of protein three times a day, whatever it might be. Good. Okay. How about your healthy fats? Oh, I'm adding avocado, I'm adding olive oil. Amazing. Those are like two of the best fats that you can get. So now what do we need to do? We need to start to work in some carbohydrates, which will dramatically improve your mood, but also give you back energy for your nervous system and your muscles.

36:59So that's been a big thing. And we just start really simple. We just start with some raspberries or blueberries, something easy with breakfast. And then we actually give them a week or so. Anything change? Is there any dramatic weight gain? Anything like that? They're going to say no. Okay. Then we move towards lunch or dinner. I like dinner. And the reason is is that if you eat some carbohydrates at dinner, you might think, well, it's counterintuitive because we're not gonna be burning them off after dinner. True, but it's overall calorie maintenance for the day. And so if you eat carbohydrates at dinner, you're gonna sleep better, you're gonna be more relaxed, in a better mood, and it's gonna improve your overall hormones.

37:33So that's ultimately what we're looking for is to meet us at where we're at in life. If you don't have a lot of output, you don't need a lot of input. That's the truth. But most people I'm sure listening to your show, they're doers and they're high performers and they need the fuel. for their body.

37:47Lindsey Simcik:Yeah, I'm glad you framed it like that, because I didn't really think about many of the things you mentioned as outputs. And so yeah, to think about again, in much more simple terms, I think is helpful for people to know how they might be undernourished, whether it's by food, or like you mentioned, breath work, that that nervous system regulation. it's very yeah it simplifies it in a way that makes sense to me um what I love too about your work is just this like blend of um let's call it like ancient healing with more modern medicine and I just think it's a beautiful blend of so many things and so I feel like that's becoming more popular and people are seeking that more because they're not getting exactly what they need going to just Western medicine.

38:44Lindsey Simcik:So I guess, what have you found to be really helpful as of late with kind of what you're seeing in your practice related to whether it's ancient healing, more of the functional medicine approach, Ayurveda, et cetera, that's been standouts as like, this has really, really had profound effects on someone's health or reversing disease, etc. Yes. So, and again, I'm all for conventional medicine and going to your PCP. But the problem is that they run a specific paradigm, which is you come in and tell them for a couple minutes how you're feeling. You run your blood work. And if nothing is wrong on that blood work, or not far enough out of range, there's nothing for them to do.

39:29And then besides that, if something is out of range, all you're going to get is a pharmaceutical prescription in order to fill. That's it. And so then, but then that's it. Like there's no hope of ever coming off of level thyroxine for your thyroid. When your thyroid is always reversible. Like unless you've had your thyroid radiated, always reversible. And we can talk about that. So like literally there's about a dozen different reasons for low thyroid. And so then you just have to work your way through what are my one or two reasons why? And that's very easy to self-assess and through integrative functional medicine at-home lab testing.

40:05So the reason why I'm so big on these is that I was sick from 17 years old to 27. Well, for the first two years, I lived right outside of Boston, Massachusetts in Medford, and amazing doctors in Boston, right? I mean, these brilliant, whether it's Boston University, Harvard, et cetera. The problem was after going to all of those doctors, they knew that something was wrong with me. They could see that I wasn't producing white blood cells, but they didn't know why. So there was no underlying root cause. So they told me I was going to have to get more sick, which was basically cancer, or I would hopefully get better, but there was no reason why it would get better.

40:40And so that, this is again, mid nineties. So then I started to be connected just by chance to certain natural health doctors, naturopathic doctors, et cetera. And this led me to a whole new world of, oh, there is actually a way to test inside of your body to see what the underlying root causes are. So I had Addison's disease. I had type 2 diabetes. I had autoimmune-based issues like rheumatoid arthritis. I had mast cell activation syndrome, all these issues, allergies, insomnia, acid reflux. And so, you know, how can one person have all of these different diseases? Well, there is an underlying root cause.

41:13The underlying root cause was I had massive gut-based dysfunction. So at 14 years old, and even throughout my whole childhood, I was put on antibiotics four, six times a year. I mean, literally the pediatrician gave my mom Z-Pax, azithromycin packs, just to keep in the house.

41:31Lindsey Simcik:Just to have, wow. My mom had four kids under five years old. We're just, whoever got sick, just pass it on to the next kid. So someone was always sick. And so that's, we lived off of antibiotics, honestly. and then at 14 i went to my dermatologist for acne never mind my uh little debbie snacks habits or my fruity pebbles i was eating or drinking kool-aid in the morning like none of that uh it's like no take take these amoxicillin pills twice a day and so i had consumed by almost 18 years old 3 000 capsules of amoxicillin in my life wow yeah so over over 700 800 a year if you look at it that And did the doctor ever ask you about that history?

42:08Never once. Wow. Yeah, never once. And so when I went in in the 90s, they never looked for candida overgrowth and SIBO and leaky gut. They were laughing at that back then, right? Now, of course, conventional medicine, Harvard-based studies are studying increased intestinal permeability, which is leaky gut, right? So I had massive candida overgrowth, yeast overgrowth basically coming up my stomach and into my esophagus. It was so bad. SIBO, which is small intestinal bacterial overgrowth, is an imbalance in the gut bacteria from essentially commensural or negative-based bacteria that's overgrown, just overtaking a lot of the space there.

42:47And then H. pylori is a specific bacteria that about a 30 people have in the world, and it can live in your stomach, but it can disrupt stomach acid, etc. So that was a big root cause. Now stress was another. I was 17 years old going into my senior year. I was the oldest born. I was trying to do well in my SATs, get a scholarship to college, like all the stress, right? I had a job. I was going to school doing sports. So stress, gut-based issues, and I had high levels of mercury, which they didn't know. And they didn't find that out actually. Even my natural health doctors, and that's why we run the minerals and metals test.

43:21It looks at five different heavy metals. Why did I have high levels of mercury? I was eating a can of tuna and rice with olive oil every single night, Monday through Friday, as a post-dinner dinner to basically try to put on muscle.

43:34Lindsey Simcik:Wow. And I thought it was just a cheap, inexpensive meal. Totally. Right? And I thought it was healthy, tuna. But it turns out it's very high in mercury. And so what I had to do was fix my gut issues. I had to rebalance my gut issues. I had to remove the excess mercury from my body. And working on the stress took a little while. Yeah. But that was the final piece to the puzzle, and I was able to work on that. And again, I want to give credit, though. My mentor, Dr. Pete, who at 27 years old, is the one who helped me put all this together. I met with many brilliant doctors, probably close to 100 over 10 years, followed dozens of different, or let's say 100 different protocols for 100 different practitioners, read thousands of different books.

44:16But I needed someone to say, let me help you put all this together.

44:20Lindsey Simcik:Yeah. And I think when I look back, she was like late 60s to me at 25, 27 years old. That seems like 100 years old, right? So I was like, this little old woman is going to help me with this. And so I wasn't like my brazen, stubborn, whatever self. I kind of let my guard down. I followed the plan that she outlined, which is bringing me back to Ayurvedic-based medicine. She was a naturopathic doctor with an Ayurvedic-based specialization. and she actually wrote the textbooks for dr vasant lad which is like one of the main doctors who came to the u.s and i understood that my body type and where i was right now we call that the vukriti and the prakriti right so the prakriti that's our genotype like that's our our who we are that's our genetics yeah and then the vukriti is who we are today that's our phenotype right so genotype and modern medicine and phenotype is who we've become and so what i needed to do was understand who I was meant to be, my body and nervous system, right?

45:17And then what I was doing that was out of balance. So that's where Ayurveda comes back in. So now today we run things like the stress, mood, and metabolism test for all of your hormones and cortisol levels and thyroid and insulin and hemoglobin A1C and vitamin D3. Amazing lab tests that you can do right at home, but we never get away from who the individual is. So you have the amazing lab data, but it should always be in conjunction with the human and the person, which is very anti-conventional medicine. Conventional medicine needs to get you in and get you out. And it's not there. It's not doctor's fault.

45:50That is how insurance is set up.

45:52Lindsey Simcik:That's what they learn. Yeah. Yeah. I mean, that's, you need to see a certain amount of people per day. Wow. The average doctor, like my colleagues that are MDs, who many of them are moving more towards concierge-based practice. But in their practice, 12 to 16 people minimum per day. Wow. Yeah. That's a lot per day to see. That's a lot. Even in my heyday when I was seeing a lot of people in my practice, the most I was seeing was six to eight. It was at least double the amount of time people were getting. Conventional medicine, average time is about seven minutes with your doctor and seven minutes of typing in your information, the electronic medical records.

46:26And that's, again, not the doctor's fault. That is how health insurance has made it. It's terrible. And it's interesting because I feel like, you know, there are different types of people when it comes to this.

46:38Lindsey Simcik:but I need to be prompted. I need to be asked a lot of questions about my health, like specific from an expert to kind of peel back the layers and kind of get to the, you know, somewhat of the root or find the direction that we're going to go. Yes. Some people come in with like, here's all the information, but I think most people aren't, don't have all that information. They're not as observant or aware of what's going on in their body. So to, that's why I think it's It's so important to spend time, to have those questions asked, to go deeper, to have these tests done, to just have as much information as possible.

47:13Lindsey Simcik:I did want to mention, because you mentioned the minerals and metals test, you can get 50 % off with our code ALMOST30. I was like, can we get a discount? 50 % off that test. It's a really important test for aging, for like so many things. Would you say across the board, that's a test that can point us in the direction of... That's our most popular one. And the reason is that it's very easy to get started for kids three years old up and adults. So it's literally just a couple of snips of hair. It's protein-based. Your hair is protein. It's going to capture what your body is excreting. And so what we're looking at is the stress-based electrolytes that we spoke about, the calcium, magnesium, sodium, potassium, all the minerals for energy and aging and hormones, and then the heavy metals, which is lead, arsenic, cadmium, mercury, and aluminum.

48:00Why those are important is those are also many that cause autoimmune issues and thyroid-based issues. So you want to see if you have those. And so, yeah, that's the easiest one to get started with. And it's at stephencabral.com slash almost 30. Great. So, yeah, I appreciate you bringing it up. Yeah, of course. It's a great one for people to start with.

48:23Lindsey Simcik:With kids, just on that note, because I feel like I find this in conversation with other moms. and just kind of in like the different mom circles I'm in, but heavy metals, why would kids have heavy metals that early? And once we find out from a lab test exactly what's happening, what are the protocols for people that young? Yeah. Did you see, this was actually just published about maybe three or four weeks ago from this recording right now. They actually looked at many of the processed foods that are the most popular ones in America. Not just candies, but processed foods. And they were incredibly high in arsenic.

49:03Really? Meaning one or two. Is that coming from rice or what? Rice is one part of it. Okay. But it could be actually multiple-based foods. We're talking about like Snickers bars and other types of candy. It's gummy bears, believe it or not, high levels of arsenic in them. Telling my husband. Yeah, this was just published. And now the nice thing is there are, because you don't want to totally deprive your kids, right? Like that's not the goal. So what's not made good. There's some other company that they make like alternatives. And those actually tested clean. Those tested clear. So with the watch of the processed foods, the nut butters, a lot of these things that we see going in, they can be contaminated with heavy metals.

49:42That's the unfortunate part to it. And the environment itself, there are very high levels of aluminum just in the air that we breathe. So the way that you're able to test this, and again, this is more for industrial-based, you look at dust-based particles. That's how we test for mold. So one way to test mold is for someone to come in, they can look at your vents, they can run air meter readings, or they can actually have you grab samples of dust just throughout the house and actually send them into the lab and those can be analyzed for mold spores. Same thing can be done for aluminum. Aluminum is probably the highest contamination actually comes from tap water.

50:16So that's why I tell everybody there's three main things because I know natural health and wellness can be overwhelming and it can be expensive. But if you start here, so think about this. The most important thing we do is the air that we breathe. So I believe every home should have an air filter. Pick your favorite company, right? But it should have a good HEPA air filter. It should have a Corbin-based base. It can have other features to it. That's great. But you want to look for 99.97, what are they called? Microparticles or cell, right? It's like that word right there that I'm searching for.

50:48Not the 99.3, but less than that. And that is actually because some mold spores and viral-based particles aren't going to be blocked. so you want to look for that really high level that you can and i always say if you can only afford one air filter get the largest one that you can put it in the bedroom at night when you're going to use about an hour before turn it on it's going to cycle through that air probably twice within that hour four times for a really strong one and then during the day bring it out to your kitchen and living area oh and then the next year if you can afford to invest another one you put one in the bedroom you keep one living area and you can just keep it like that especially if you have pets they track stuff in all the time as well we love dogs i love my dog but you know he It brings things in on its paws and from outside.

51:26So it's great to have. The second, so clean air, clean water is the next one. People say, no, my city tests my water. At most, your city is testing most likely for 400 contaminants. That's it. There are tens of thousands of contaminants that could be in the water. And the pharmaceuticals are never tested for what's in the water. And you can look at the tests. Antidepressants, hormones, et cetera, are always in the water-based supplies. So get a good water filter.

51:51Lindsey Simcik:I'm over people saying New York has drinkable tap water. Nobody should ever say that. I grew up hearing that. Like, oh, New York water is the best. I'm like, everyone needs to stop saying that. I'm like, maybe, I don't know if it tastes good. I filter my water, but like, what? Yeah, I mean, it's just, because it's always then it's like your city that it happens to and then it's too late, right? So it's like for the investment to get a good water filter, that's my number two. And then number three would then be choosing more organic options or at least looking at the clean 15 and dirty dozen. So if the skin can be peeled away from it, probably okay to buy conventional.

52:31Better if you can do organic because it's probably going to have more nutrients from the soil itself. But if not, stick to the clean 15. So people say, well, if I can't get organic strawberries, should I not eat strawberries? I often say yes. Like you choose another fruit, even if you love strawberries. And the reason is strawberries are loaded with pesticides. they're always the number one or number two food for pesticides yeah um are you even if they're

52:54Lindsey Simcik:organic this is a niche question but like we're washing it we're doing a proper wash all the things because like i feel like there's i don't it's not that i don't trust but like if there's a downwind on like people spray i don't know what's happening i mean they're growing on the side of the highway yeah like always good to wash and you can just fill it up in a big basin of if you have hydrogen water amazing if you have um some little bit of baking soda you put that in so that's that's great too yeah that's what i think it was good for so many different things so many different things tell me what else well there are many people that are using baking soda right now for performance and recovery so they're taking a half a teaspoon in some water before exercise okay actually helps to buffer a lot of that oxidative stress and lactic acid etc being produced by the body some people are using it again not providing any medical advice here for cancer-based protocols, which at a tissue level, because people like to say, well, there's no such, because it's very alkaline, right?

53:48So baking soda is very alkaline. And so people say, well, there's no such thing as acid alkaline in the body. There is, it's just the blood, which people get confused over, stays at a very certain pH. So the pH of the blood is about 7.35. That's what it maintains. If you go above 7.5, you're dead. If it goes below 7.2, you're also dead, right? So the body's great at maintaining that level. It will just pull calcium and pull different electrolytes that it needs in order to be able to balance that pH level. But at a tissue level, not everything is the same. And so at a tissue level, you could actually have a much more acidic-based space.

54:22And so a great study just came out on pancreatic cancer, probably arguably the most deadly cancer in the world. There is no real five-year survival rate for terminal-based pancreatic cancer because it is a rare exception if you live. there was a study and the difference is people took on average one teaspoon of baking soda per day 40 of the people were still alive after five years amazing yeah and i'm not gonna say that's the only thing you should do of course i talked in depth about cancer support all these things but for a very inexpensive sodium bicarbonate based product wow why why not yeah why not wow but again i just want to go back everything in balance so if you take sodium in you do need potassium in the body, which is from lemons and limes and coconut water and greens and all those things to get your potassium as well.

55:12Lindsey Simcik:Okay, great. Okay, I have a few places I want to go. I think the next place I want to go is brain health. You mentioned earlier Alzheimer's. I feel like we're maybe getting to the age, those listening, where we have parents who are a bit older, grandparents, et cetera. And, um, Kristen's been, Kristen's been open about this. Her dad has Alzheimer's and Parkinson's and, um, just kind of seeing up close these, these diseases of the brain that, um, I think make us nervous that are we doing what we can today to hopefully prevent them. But I would love, I would love to talk to you about this and just, are there ways we can prevent this?

56:00Lindsey Simcik:Like, is this something that is genetic? It is something that I think you mentioned over time it develops, but what can we be doing today to really protect our brain, to keep it as healthy as possible, have our cognitive function be as just like sharp as possible for as long as possible? Yes. So, I mean, there's two parts to it, like keeping sharp cognitive processes, meaning like recall and memory and just being witty, all of those things, that really comes from reducing overall cortisol levels so when you are stressed all it really like it's such a big part to it right so when yes i talked about this i think last time but it was the neuro endo immune system so the way the body dysfunctions is the nervous system is overloaded then it affects the endocrine system so that's the endo and that's typically cortisol dysregulating lower testosterone in men that's why most men don't need testosterone replacement therapy They honestly don't.

56:54Before the age of 60 years old, it is so unlikely that you actually have low testosterone. Now, again, clinically, yes, you run a lab test, you have lower testosterone, but is it from deficiencies in zinc? Is it from deficiency in vitamin C? Both of those would lead to low testosterone. If you increase levels of cortisol, it will drop levels of testosterone. And in women, it drops levels of progesterone. So now you end up with estrogen dominance. so women end up with water retention like they try to lose weight but they can't lose weight because it's really a lot of water retention they might end up with a lowered mood irritability they might end up with um a little bit of facial hair they can end up with oily skin acne adult based acne uh what are a couple of the other ones um more more lower thyroid because again cortisol will lower thyroid as well thyroid is a metabolic based hormone and process so the cold hands, cold feet, poor circulation, brain fog, thinning of the hair on the top of the head, dry skin, that's more of the lower thyroid.

57:52And that is because as you increase a hormone called glucocorticoids, which is cortisol produced by the adrenal cortex, and that's in response to stress, or even, again, it can be fasting too long and just having a black coffee on top of it. It could be from doing interval-based sprints, fasted as well. Some of these things don't affect some people and some they do but that will drop thyroid hormones so it'll actually block the conversion of t4 to t3 from active thyroid so we have to always kind of move downstream there as to what might be happening all right so downstream are the symptoms the cold hands the cold feet that we just spoke about but upstream okay we have low thyroid all right well peel back the onion a little bit more why is that um you have poor thyroid conversion because you're producing too much cortisol okay well why are you producing too much cortisol and then we have to start to look at those specific reasons.

58:40I got way off track. No, no, no, it's good. What was the question?

58:44Lindsey Simcik:I'm following the brain health. Okay, brain health. So cortisol is one of the factors that can increase beta amyloid plaque in the brain. And just on this cortisol piece, because we have everyday stresses, right? Yes. And everyone handles stress differently, like you said. Is it about how quickly you come back to kind of like a homeostasis or whatever you would call it. Because I don't think we can avoid stress. So like, I guess what is like really impactful when we are in constant stress? Yes. It's chronic, unrelenting, and especially at night. So we are diurnal beings. We are meant to, because it's not just cortisol, but cortisol has these downhill effects, right?

59:27So we're meant to produce a massive surge of cortisol between six and 8 a.m. in the morning. That's totally normal, totally natural that's why we shouldn't need our coffee at really six to eight in the morning and if we want to reduce that cortisol if it is too high food enabling carbohydrates help to break that now it doesn't mean that you need to sit down to a bowl of cereal right you can still have your protein all these great things but some carbohydrates help to just keep you balanced that's why breath work is great to start the day meditation prayer is great to start the day but then after that and you can run this on a um a stress mood metabolism test it's four tubes basically of saliva and that's something you can't do with blood work.

1:00:04That's one of the big, that's one of the, that is the test that I ran that told me to then go back to conventional medicine to see if I had Addison's disease, which is that you can't produce cortisol. So producing too much cortisol, really bad. Not producing any cortisol, you feel like you have flu-like symptoms and you're a zombie every day. You never wake up. So it's pretty brutal, but I won't go down that path. So that's not what most people have to deal with. So the evening cortisol, why is that an issue? Because it does not allow for the production of melatonin. And it does not allow for brain-derived neurotropic factor, BDNF, to be produced as well.

1:00:39So when you're sleeping, you really, I mean, it is important to track sleep. I really believe that. So you don't need to wear wearables all day long. But wearing something like an Oura Ring or Whoop or Withings, like whatever your favorite device is, you want to get 90 minutes or more of deep sleep a night. and you want to get two plus hours of REM sleep. Think of deep sleep more for recovering the body and think of REM sleep more for rejuvenating the brain. And if you're producing high levels of cortisol and you're waking up around the 2 to 3 a.m. hour, most REM sleep is from 2 a.m. to about 6 a.m.

1:01:15So if you have sleep issues the latter half of the night, that could be affecting your long-term brain health as well.

1:01:20Lindsey Simcik:Okay. And then there is a genetic component. So the genetic component is called the ApoE genotype. It's an allele. You either have the 3-4, which means you're more susceptible to dementia and Alzheimer's, or you have the 4-4, which means you're 93 % more susceptible. I think I have the first one. So the first one is very common. About 26 % of the population has it. So the issue is this. it means that you are more prone to inflammation in the body so recovery has to be a real focus right and you also don't clear cholesterol from your body as well yeah that's why people saying that red meat is not a problem and high cholesterol is not a problem it's like we'd be careful who we're saying that to yeah that's not a problem for about a third of the population for another third it's neutral it's based on oxidative stress and free radicals that we're talking about and for one third it's actually quite detrimental they can't clear it as well and this also then leads to brain-based inflammation and brain-based issues so even though someone can be far more prone to alzheimer's they're still not likely to get it all the other things have to fall into place as well it just means they're more prone to it so if they allow inflammation from alcohol processed food the improper diet for them not enough fiber fruits and vegetables these types of things, they're going to be more prone to it.

1:02:45Another big factor is sleep. So we don't focus on sleep enough as part of our overall anti-aging. We kind of look at everything else that we could do when sleep is the best supplement in the world.

1:02:57Lindsey Simcik:Yeah. And honestly is. It really is. I was talking to someone else about this the other day. We were talking about another topic, but like it came back to sleep. Sorry, boring, but sleep is just so important for so many reasons. Okay. So... And And then there are early detection tests for Alzheimer's that we have. We should talk about it. So if you think about it, it's unlikely you get diagnosed with any form of dementia, which again, like Alzheimer's fits into the dementia category. It's unlikely before your late 60s. So the thing is this. If you don't have heart disease, call it high cholesterol, high triglycerides, etc.

1:03:38If you don't have higher hemoglobin A1c, which is moving towards prediabetes or diabetes, and you don't have high blood pressure, the likelihood you're going to get Alzheimer's is quite low. Alzheimer's is often referred to as type 3 diabetes. So it is inflammation that is then essentially glycated, oxidized with higher levels of blood sugar. So our real job, there's five, I would say, and this is because it's really so important. There's no reason for 99 out of 100 people to die before their late 80s or early 90s, like legitimately not doing anything special if they don't get the big five, which is heart disease, high blood pressure, type 2 diabetes, Alzheimer's, dementia, or cancer.

1:04:24Cancer is the only one we can't find 10, 15 years in advance, always. Now we can the same way we look for Alzheimer's. So there are full body MRIs and I know they're expensive and I know it's kind of elite right now. I totally get it. But that price is going to be falling over the years. It has already gone. When I was looking at this with clients back in the day, let's call it 20 years ago, it was about$8 ,000,$10 ,000.

1:04:51Lindsey Simcik:Wow. Then a decade ago, it went down to$5 ,000. Now it's like$1 ,500? That's right. Something like that? Yes, exactly. And so for the full one, it's like$2 ,000, but that does your brain. And this is like a pre-nuvo type thing. Exactly. I'm sure there are a bunch of different... So pre-nuvo is the premier. And that's because, and again, I have no affiliation with them. When you walk in, it's like a spa setting. Right, right. So it's not as ennerving as, you know, walking into a hospital setting, right? And so anyway, like to, they literally have you watching Netflix, like watching your favorite show while you're doing it.

1:05:21So it's pretty straightforward, pretty easy. But there is obviously the claustrophobia type aspect of it. But they will scan your body for blood clots, aneurysms, joint-based issues, early cancer, literally at a millimeter. That's it. And they'll look for Alzheimer's. And so if you do that and you get the all clear. Now, remember, everybody's going to have little cysts, benign cysts, and those types of things. Nothing to worry about. That will occur in almost all of us. But if you start to say, oh, there's some early signs of brain-based deterioration, you can work on it and reverse it. When you look at things like the MEND protocol, and that's even a little bit more complicated than it needs to be, they can stop, halt, or reverse 90 % of all cases.

1:06:06Lindsey Simcik:What are we talking about when we say reverse? Like what is involved in the protocol? It always goes back to, so my first book, The Rain Barrel Effect, I talked about the de-stress protocol. Diet, exercise, stress reduction, tox removal, rest, emotional balance, scientific back supplements, success mindset. So they don't talk so much about the emotion and the success mindset. I think it's critical. And the reason is, it's like, how do you stick with it after 12 weeks? Of course. Right? Like that's such a big part to it. You have to have a big why. So like my why is I don't love doing cardio. I really don't like just like on a treadmill, on a bike for 45 minutes, you know, whatever it is.

1:06:43And doing, and you really need 150 minutes a week. Like it's a good amount. But then I'm thinking about like, well, this isn't fun, but having Alzheimer's, which like maybe I'm more prone to it or other, that's not so fun. I want to see my daughters grow up and I want to maybe see my grandkids. So like, okay. So you just have to have this why that just enables you. And then we call it like habit stacking or temptation bundling. It's like now I have a garage gym. I was sharing with that earlier. And I put a TV in there. I never watch TV. But I can click that on if I'm on the bike or the treadmill or an iPad and just put it on and watch.

1:07:17I don't even watch TV, but YouTube videos or something like that. And it just helps the time. So like you just have to find a way to do these things. Exactly. And that's kind of the success mindset. So the med protocol is basically, it's all these different supplements, which they're all beneficial, like coenzyme Q10 and B vitamins, all that. So like we know that those work. However, if you do integrative functional medicine at home lab testing, you'll actually know the ones that you need versus just taking 30 of them because there are a lot.

1:07:43Lindsey Simcik:It's important, yeah.

1:07:47yeah that's why i i've only gotten hip to like lab testing like just testing for myself in the

1:07:54Lindsey Simcik:last i would say five years and it's been so important because i feel like before that i was just willy-nilly like trying things doing whatever and not really understanding the levels of my body how it's affecting me how it could be kind of popping up other symptoms because there's an and balance. So I can't emphasize enough how important it is to get tested, you know, get your labs done. Obviously you have so many that are so, so helpful. Um, and when people always ask like, what labs do I run? The minerals and metals test is a great first place to recall the starter kit, which is just the minerals and metals test plus the candida metabolic and vitamins test.

1:08:32Okay. So minerals and metals is all your mineral levels, which in my opinion are more important than your vitamin levels because it literally runs the electricity and energy of the body. But we can come back to that. And it runs your heavy metals. The candida metabolic and vitamins test runs all of your vitamin levels. So it's a nice match to your minerals. And it looks at gut function, mitochondrial function, which is critical for energy. So those are great to start. But in my new book, Personomics, I give you self-assessments. So maybe you can't run every test, like we call the big five. That's okay.

1:09:04If you run the assessments, there's just a self-assessment, it's basically quizzes, and you answer more than three, you're like, this is an area to go deeper in. And the nice thing is the resolution is usually eight to 12 weeks. So it's not the rest of your life. And so my goal for people is not to kind of dance around what needs to be done, is to just say, okay, I'm going to do this. This is going to be the year. I'm going to make this fix and then focus on I'm doing this because I want my energy back. I want my mood back. I want all those things that we all want. Right. I know when I get, cause I'm not infallible.

1:09:41Uh, I travel a good amount. I get a virus from, you know, we, we live on these aluminum tubes and people are hacking up a lung. I'm like, how do I always sit next to the person who literally sounds like they are dying? And I'm always just like, just breathe. And, um, and so, you know, we, we get sick. And then you, you, on those moments, like I have low energy, I can't exercise the same degree. I can't do these things. My sleep isn't as good. And you're like, oh, wow, I actually miss, you know, those things. And I don't want to get too far away from that. So eventually true health and energy becomes your new normal.

1:10:15And that is what you want. And then when you shy away from that, you're like, and that happened to me in my later twenties, I was like, you know what, it's just not worth it for me to go out and have a bunch of drinks on the weekend. It's just not like no

1:10:27Lindsey Simcik:matter what yeah i think a lot of people are kind of coming around to that too like at this you know transition that we speak to a lot 20s to your 30s like alcohol just doesn't have its appeal anymore it's we kind of make the connection between how we feel and then how we want to feel and how doing that over and over is yes so detrimental actually it would be interesting to hear um the connection between brain health and alcohol use and even i don't know if you want to talk about weed use but But I just feel like there's a super connection there. I have people close to me in personal in my life that I'm like, I wish you knew that the amount that you're drinking every week was affecting this memory recall that you're having trouble with or inflammation, things like that.

1:11:13Well, my genetics, I'll be the first one to tell you, are horrible. I always say God had probably had a lot of fun putting together my genome. So when I look at my genetics too, in terms of alcohol, I know that having more than two drinks clinically per week for a male, three maximum, is gonna increase my chances for cancer. Just not worth it to me. Two to three, all week. Not two to three per day, like you say one to two, right, per night? Two to three per week. Now, is everyone going to get cancer for drinking two to three? No. So I spend a good amount of my year, probably three to four months of my year in Maine.

1:11:50I love just the wilderness of Maine. It's great. And all of my neighbors, honestly, average age is probably 88 years old. So we've got a 96-year-old right across the street from me, beside me in their later 80s. And two of them, not all of them, but two of them have a nightcap each night. And at four o 'clock, they, now it's not nine o 'clock at night, that's going to affect their sleep as much, but at four o 'clock, they have a drink every night. now if you look at it though they live true blue zones but in me they don't overeat they walk daily they don't have a lot of stress right they have their family around them or visiting they're independent and they have this drink now some people look at a drink as a hermetic stressor for the body so in a small amount it actually can make the body a little bit stronger and so i'm not saying that people should drink and I definitely don't believe it and I absolutely know the research shows that it's going to lead to more cancer.

1:12:49For some people that one drink like my neighbor, it is their moment in the day where they get to relax. They get to unwind from the day. Now they did a little gardening that day. They didn't do a whole lot, but that's when they look forward to. And again, it comes back to the nervous system. It relaxes the nervous system. They get a good night's sleep. They probably go to bed at 9, 9.30 at night. They sleep for what their body is able to sleep and they do it again the next day. So I don't want to totally write off alcohol, but if you're doing it because you believe that there might be some health benefits like the resveratrol and red wine, I can assure you that is not the reason to consume any alcohol.

1:13:24Yeah. And if you are worried about Alzheimer's and you have the APOE3-4 or 4-4 genotype and you have a family history of cancer as well, I would say no alcohol at all.

1:13:35Lindsey Simcik:Yeah, I know. And it's a hard thing, I think, for people to kind of reckon with and even imagine not having, because I do think it's such a social thing. It's a comfort thing. It's a, you know, a reward thing. 100 % it's a social thing. I mean, think about it. Like if you go out on a boat with individuals or you go whatever, even play golf or whatever might be like having a drink. Like it's just like part of the thing. but i will say this is that this next generation of early 20s are now not consuming alcohol nearly the same way yeah and there are a lot of alternatives so people always need that little something so now it's like okay this is uh you know a wellness-based cocktail with l-theanine and some ashwagandha or maybe it's a little bit of cbd and we could talk about that as well um so they're doing things yeah a little bit differently and it's just if you grew up that way in your maybe later teens, college and early 20s, it's hard to break that because that is the kind of trigger in the brain when you get together with people.

1:14:38That's how you do socialize. So what would it say in those, like if I'm going out with my friends and oftentimes like 90 % of the time, I literally will not drink. I'll get a sparkling water and I'll go crazy and I'll get a splash of cranberry juice and squeeze a lime and you know, wild, right? Cause I never do that at home. And And so that's what I'll do. But, you know, if I'm going out and we're at a nice steak restaurant or whatever it might be, and again, these aren't going to be grass-fed steaks or whatever. This is just a flex meal. This is being a human. This is enjoying yourself, right?

1:15:05I might get a glass of wine, but I might only drink a quarter of it. Yeah. Like I have it there. I take a few sips. I'm enjoying it, and it is what it is. Yeah. But, yeah, eventually a big part of it is you being okay with you and being okay with not drinking.

1:15:21Lindsey Simcik:I think that's the biggest part. Yeah. Because I think we just, we want to be a part of the group and also a part of the experience that they're having. And then we don't trust that, like, we can have a good time no matter what. There's just, there's a lot happening there. Making people feel bad that you're not drinking, but they're drinking. There's a lot of dynamics. Yes, exactly. That's a whole thing. Just to kind of close the loop on this piece of it, just substance use. Do you find any correlation in patients coming to you with like current or prior marijuana use having any effect on what they're experiencing now, say anxiety, anything with inflammation, brain and anything that you're seeing in that realm?

1:16:06Lindsey Simcik:because I feel like I didn't really smoke at all, but I have a lot of friends who did for a long time, and I have someone in my family who did for a while, and so I'm always curious about kind of the effects of that, the lasting effects or temporary effects. There are competing studies right now, and so some studies are showing that long-term marijuana use, so cannabis use, can lower testosterone levels. They can deplete dopamine levels, ambition, drive, et cetera. And there are some that show that it's perfectly fine. And I think they affect people in different ways. The problem is, and I actually like a lot of Dr.

1:16:45Daniel Amon's work. Have you ever had him on the show?

1:16:47Lindsey Simcik:No, actually. So, you know, he's done probably more brain scans than anybody. Like we've run 300 ,000, you know, probably lab tests, probably more, 400 ,000 lab tests. We've got a lot of data. We've got over close to 10 million biomarkers of data. So we really know what affects what in the human body. but he does that for the brain. And so he released work that shows, again, so you can look at clinical studies of like 30 people. Well, he's done 100 ,000, right? And so he shows, and I actually did not believe this. And so, you know, looked into his work and it's true that at least what he sees, cannabis is more detrimental for the brain than alcohol.

1:17:24And actually, again, it's hard to believe, but these are the scans that he's showing. What I will tell you is this, that's undeniable is that vaping is worse than anything.

1:17:34Lindsey Simcik:Wow. Because of the chemicals when individuals are vaping. So if you're consuming a flavored anything, assume that it is absolutely toxic for your body, deteriorating your brain cells, as well as harming your entire body. So that I can't recommend. CBD is a different story. And so I would say that I don't think anybody needs to be or should be dependent upon any of these things, but CBD can be remarkable for pain, for inflammation, for potentially cancer, et cetera. Usually 25 to 50 milligrams is a good place to start. We like full spectrum, we like organic based CBD and people can start slow and they can try that if needed.

1:18:16But while always working on, what is the reason you're using this for? The underlying root cause, it always comes back to that. Cause you're not deficient in cannabis, right? So anytime you say like, well, I'm using this for this, got it, but if that is not part of the human makeup you're most likely deficient or you have too much of something else.

1:18:32Lindsey Simcik:Yeah. My last question is around peptides. And I guess we could talk about GLP-1s if we want to kind of go there. I think it's a huge conversation. So I think just generally speaking, are you excited about what you're seeing? What are you excited about? Is there anything that you're like, I don't know yet based on the research, because I feel like in my world, I don't take any peptides yet, but I know a lot of people who do and are kind of on their stacks and doing all the things. And I'm kind of jealous because I'm like, oh God, after my motherhood era, maybe we'll revisit. But yeah, I, or my being pregnant years, I'm just curious your thoughts as someone who I deeply respect and know you know a lot and are an expert.

1:19:25Lindsey Simcik:What do you think? I mean, I honestly believe that it's still too early. Yeah. And it makes me nervous. I want the best for everybody, truthfully. Yeah, same. And since I am a board-certified doctor of naturopathy, but I'm an integrative health practitioner, that means I'll use the best of anything. So when we do cancer support-based protocols, we'll look into things like low-dose naltrexone or antiparasitics, et cetera. Like the research on those are actually pretty good. And so I'm not against that. But when we're looking at peptides, they are not harmless. I just want to put it that way. A lot of people are saying they're harmless.

1:20:03Yes, and I think that that's concerning to say that. So even think of like two of the safest ones. Let's look at BP-157 and maybe like TB-500 or something like that that you might stack it with. Okay, great anti-inflammatories, good for the joints, potentially good for the gut etc they also promote angiogenesis so by its nature promotes good blood flow good circulation because that's how you heal the joints and that's how you heal the rest of the body well if you have cancer growing in your body that can increase blood flow to the cancer space tumors a lot of what we do in cancer support is anti-angiogenesis so we look at things that actually stop and block blood flow to these tumors and again probably great 99 out of 100 but what about the one person so i'm always looking out for the edge cases that one person uh glp1's great again i think a great discovery a great breakthrough because a lot of people are upset because people should have to eat properly and do this i get it totally understand that people should but there are a lot of people that are trying really hard and they're not losing the weight yeah right or they can't afford all the best foods or the best supplements and those types of things.

1:21:16I look at it this way. If someone's 100 plus pounds overweight, looking towards a GLP-1 for a certain period of time may not be a bad thing. Because being 100 pounds overweight, you're going to end up with heart disease, high blood pressure, type 2 diabetes, and probably cancer. And I'm not saying that you are going to get it, anyone like that, but the likelihood increases. Why the cancer piece?

1:21:41Lindsey Simcik:Because of the others? Obesity increases cancer. Yeah. Got it. Many, many forms of cancer because of high amounts of inflammation and most likely have elevated levels of blood sugar. So you do have elevated levels of blood sugar with that point. So the big thing is this, that those GLP-1s could save their life, but because you have to weigh them against side effects. What are the side effects right now? If you read the label, the label literally says, this product causes cancer cells in the thyroid in lab rats, in mice. Now, is that proven to happen in humans? No, but anybody can look this up.

1:22:19That's literally what it says on the label. Now, might it be a very high dose for the mice that they're given to? Sure. May never happen in humans, but that's worth looking into. It's causing vision, blindness-based cases in some people. There's a$2 billion lawsuit right now, civil action lawsuit or class action lawsuit against certain GLP-1s. I don't want to name the names right now. What else is there? They're gastroparesis. So the inability to really digest food slows the digestion. That doesn't always come back when people come off of them. Then there's at least one third of the weight loss is muscle and bone.

1:22:54And so when that is loss...

1:22:56Lindsey Simcik:Bone, I didn't know that. And bone loss. So again, for women, it's mainly... No, definitely men are taking them as well, but it's mostly women. And so if you already look at after the age of 27, you're losing bone mass and muscle mass how much muscle the average woman loses about five pounds of muscle per decade so you're like oh no big deal right okay well five pounds 10 pounds 15 20 over 40 years 20 pounds of muscle loss is significant that means a dramatic lowering of the metabolism but not only that muscle is what helps to keep the blood sugar out of your blood as well meaning like helps to bring of the tissues after you've been able to convert it.

1:23:34So all of this to say is that I don't think that anyone who just needs to lose 30 pounds, 40 pounds should be using GLP-1s. I don't. There's so many other things as well. Like if you've heard of like, again, we'll just use the term Ozempic face. You're losing body fat and you're losing so much fat from your face. And so then you're saying, okay, well now I need to go do fillers or I need to go do all these other things. What I would rather have people do or do the fundamentals that lead to a healthier life in the first place. So let me just give you an example because again, diet, exercise, I get it.

1:24:12Nobody wants to hear any more of that. There are actually natural things that you can do. So berberine, these are all natural GLP-1 producers. Berberine, EGCG from green tea, curcumin and resveratrol and ginger as well. Those will all improve GLP-1 production, all good for the gut where GLPs are actually made. And there is a specific form of berberine called glucovantage, which has been shown to double your own natural GLP-1 production. So you get the appetite suppression to a degree and you get the weight loss benefits as well. So what I would say is just with peptides in general, I think we need more time, more studies, more research.

1:24:57Don't use yourself as the guinea pig first. Do everything you can from a natural health-based perspective. And then if you need to layer on, maybe there's a time and place for that. But people just use them too early. 30s and 40s is just so early to use all of these things.

1:25:11Lindsey Simcik:That's a really interesting piece. Yeah. Because I feel like some people think, well, it's preventative or I'm getting ahead of They kind of like they say with like Botox, like I'm going to do it early and then, you know, I won't. There's nothing at all in the research that shows that peptides are preventative for anything. They literally, well, for the most part, we're talking about ones that are promoting hormone production, etc. Right. There's just not enough research. There's not enough years to show that. Yeah. I mean, we need real years to be able to show that these things don't cause cancer.

1:25:41Lindsey Simcik:Get them. That's the thing is you can get anything now. And now anyone can kind of sell them. And then I think the big thing that I'm curious about, I can talk about this forever, but is like the support. So I know there are some people and physicians out there that provide support through the process of being on them, especially GLP-1s. I think there's, you know, the right way to do it. But then a lot of people aren't. They're just taking it. and they're losing weight and they're like oh this is great but they're not focusing on lifting weights on their diet on actually changing what might have caused this in the first place if it's not genetic and so yeah there's absolutely a right way and wrong way to do it so again if you're going on glp ones work with a practitioner that you're weight training two to three times a week that you might start to do a little bit of cardio but the weight training just like you said is the most important to keep the muscle on yes so that you don't lose that and the bone mass as well and then i don't want to deny the benefits of someone using peptides meaning like they're going to feel benefits from it yeah what i worry about five is five to ten years from now and people aren't they're doing one peptide right well that's where they start then they're saying wow this really worked and they're on two or three or a half a dozen and they're that's where the studies are not that's they're not testing them on like pharmaceutical drugs like working together this this works for this but it hasn't been tested with all the chemicals in the environment and the other half a dozen pharmaceuticals that people are on as well.

1:27:10So again, I think we just want to go a little bit low and slow with that. Try to stick to the foundations of what does truly work. Find out what your deficiencies are, what your toxicities are that are truly leading to the whole reason why you need peptides in the first place.

1:27:24Lindsey Simcik:Yeah. Yeah. That's the whole thing. Personomics, the end of all diseases, the book. Last, last question. The end of all disease is a pretty bold statement. It is bold. The book was originally just supposed to be personomics, but nobody has any idea what that is. No, I love that this is on the cover. And you truly believe that? A hundred percent. And the reason is, is because just to kind of finish it out, I had my own health issues. I no longer have any of those diseases. Someone comes in with low thyroid. One person with low thyroid is from the elevated cortisol. Another is because they have low levels of iron.

1:27:58No one ever told them that you need iron to actually convert thyroid hormone. Another person is low iodine. Iodine is actually what makes up thyroid-based hormone. Another person is low selenium or low zinc, which converts T4 to T3. Another person has gut-based issues that's leading to the leaky gut, that's leading to the inflammation, that's leading to the Hashimoto's. If you correct for which one you have, you no longer then have low thyroid or Hashimoto's. So all disease is figureoutable now. It wasn't necessarily 30 years ago, but it is now. and so people just take the time it doesn't take a lot of time but they take the time to look inside themselves find out what their deficiencies are what those their toxicities are again the goal is to help people get well and yeah and then pass it on like that's the thing it's like you have all this information that you can now share with your kids i have the information that i was fortunate enough to be able to now pass on to my daughters i hope that they pass it on to their kids one day too yeah that's what this is really all about yeah so good this is incredible

1:28:55Lindsey Simcik:every time you're here. Thank you so much. And again, you can get the metals and minerals test 50 % off, which I think you should absolutely do. And if you have kids, do it for them. I'm going to do it for Mav. stephencabral.com slash almost 30. Yes. Okay, great. Amazing. Thank you so much for being here. Thanks so much for having me. This was great. Please get the book. This was awesome. It flew by. All right. Thank you, guys. See you next time.

1:29:23Lindsey Simcik:Thank you so much, Stephen. We appreciate you. He's on Instagram at Stephen Cabral, and you can get your minerals and metals test 50 % off when you go to stephencabral.com slash almost 30. Enjoy. See you guys on the next one. We love you. Love you. Bye.

1:29:54Thank you.