In short
Listener Questions #27 on (1) how one ant queen can produce males of another species via “obligate cross-species cloning” and sperm parasitism, and (2) how people with aphantasia experience mental imagery in physics, plus (3) why Demodex mites live on human faces and what triggers their nighttime mating.
Guests
Cal Penn (hosts/promotes Earsay book club segment; not part of the science Q&A). Main hosts are Daniel (particle physicist) and Kelly Wienersmith (studies parasites and space).
Key claims (ants)
Ant females are diploid and can produce haploid males without mating; species 1 queens produce species 2 males (~9% of queen-laid eggs) only queens do this; workers are sterile hybrids. Species 2 males in species-1-only regions carry species-1 mitochondria, implying origin from species-1 queens. Authors propose females “clone” species-2 males using stored/inserted genetic material; mechanism unknown.
Notable examples
Mesor ibericus and Mesor structor overlap; a ~1000 km gap still yields hybrids. Demodex follicularum/brevis live in follicles, eat skin cells/grease, mate on faces at night; mites may use light cues or melatonin (circadian-clock gene loss). Aphantasia discussion references Einstein imagery and Oliver Sacks’ amphetamine self-experiment.
Written by AI. May contain mistakes. Listen to the episode to check what was said.
Chapters
Tap a time to open that second in VOThe Beauty and Creepiness of Parasites
2:31 to 5:33
Discussion on the creepy and beautiful aspects of the universe and parasites.
“Do physicists see the universe in their mind's eye?”
Listener Question Introduction
5:33 to 6:16
Introduction to a listener's intriguing question about ants.
“And it's also, I got to say, a confusing universe we live in.”
Exploring Ant Reproduction Mysteries
6:16 to 7:10
Discussion of a study about ant queens giving birth to two species.
“This is Jamie Pfeffer from Westfield, New Jersey.”
Understanding Hybrid Ant Offspring
7:10 to 8:27
Explaining how ant queens can give birth to different species' males.
“So, okay, so you can get like a donkey and a horse.”
Ant Mating Systems and Genetic Relationships
8:27 to 10:40
Exploring the complexities of ant genetics and mating systems.
“So this is like dogs give birth to dogs and occasionally a cat.”
Sperm Parasitism in Ants
10:40 to 13:33
Delving into the concept of sperm parasitism in ant species.
“So that explains like how the siblings are related to each other.”
Evolutionary Implications of Hybrid Ants
13:33 to 14:01
The evolutionary advantages of hybrid ants and their reproductive strategies.
“And when Jamie asked you this question, do you think he knew there was a parasite angle on it?”
The Ant Mating Mystery
14:01 to 14:28
Explore the unusual mating requirements of a specific ant species.
“Is there an evil cackle that happens along the way, you think?”
Producing Hybrid Ants
14:28 to 17:47
Learn how species one ants can produce species two males without their presence.
“She can't produce these workers anymore unless she finds species two, males.”
Cloning Mechanism in Ants
17:47 to 22:52
Discover the hypothesized cloning mechanism that allows ants to create males.
“So one possibility here is that a lot of invertebrates are able to store sperm.”
Show all 32 chapters
Defining Species and Xenoparasitism
22:52 to 23:33
Discuss the implications of xenoparasitism on species definitions.
“The new word is xenoparis, meaning they, quote, need to produce individuals of another species as part of their life cycle.”
Listener Questions Segment
23:33 to 26:55
Engage with listener questions about aphantasia and its effects on physics.
“So tune in for the answer in a future episode, and let's see if Jamie feels like I managed to figure this paper out.”
Temple Grandin's Insights
26:55 to 28:00
Explore Temple Grandin's experiences and insights into understanding livestock.
“We love getting questions from listeners.”
Exploring Mental Imagery in Physics
28:00 to 28:49
Learn how physicists utilize imagery in their work and the spectrum of mental imagery experiences.
“but can also include auditory, smell, and even taste.”
The Spectrum of Imagery: Aphantasia to Hyperphantasia
28:50 to 30:18
Understand the variation in mental imagery abilities and its implications on personal experiences.
“So she works with livestock and tries to create ways to make their lives better and to have more humane practices.”
Historical Perspectives on Mental Imagery
30:19 to 33:18
Discover the historical context and psychological theories surrounding mental imagery.
“He thought everybody was being figurative.”
Neurological Cases and Aphantasia
33:19 to 35:07
Learn about neurological cases that reveal insights into aphantasia and mental imagery.
“And it can get stuck in them for a while.”
The Effects of Mental Imagery on Creativity
35:08 to 37:12
Examine how different levels of mental imagery affect creativity and artistic expression.
“it or hearing about it described on the radio.”
Diversity of Thought in Physics
37:13 to 39:47
Explore how varying mental imagery impacts problem-solving in physics and science.
“is an issue, that there really is a difference.”
Diversity of Thought in Physics
42:35 to 43:27
Explore how varying mental imagery impacts problem-solving in physics and science.
“can flare less with Epiglis, a once-monthly treatment for moderate to severe eczema.”
Diversity of Thought in Physics
43:35 to 43:45
Explore how varying mental imagery impacts problem-solving in physics and science.
Introduction to Listener Questions
43:45 to 44:40
Daniel and Kelly begin answering listener questions, starting with face mites.
“Okay, we're back and we're answering questions from you, from listeners just like you, who had a moment of curiosity that they couldn't scratch themselves.”
Understanding Demodex Mites
44:40 to 45:58
Exploring the existence and behavior of Demodex mites living on our faces.
“So what's up with these little face invaders?”
Mating Habits of Face Mites
45:58 to 47:18
Discussing how Demodex mites mate and their nocturnal activities.
“So without a microscope, you can't see them.”
Circadian Rhythms and Mites
47:18 to 48:35
How Demodex mites may rely on external cues for their activity patterns.
“OK, so it could be the light, but they also and this is sort of interesting.”
Origins and Impact of Face Mites
48:35 to 50:20
Discussing how people acquire their face mites and their effects on skin.
“So actually, most people by the time they're adults have mites.”
Ecosystem of Face Mites
50:20 to 51:48
Examining whether face mites have beneficial or harmful effects on humans.
“here's another opportunity for me to mispronounce something.”
Demodex Physiology and Lifespan
51:48 to 53:19
Learning about the lifespan of Demodex mites and their waste management.
“And that patch will sort of grow back in again.”
Evolutionary Implications of Mites
53:19 to 54:28
The evolutionary reasons why Demodex mites thrive on human faces.
“They also found a tiny penis on their head.”
Listener Feedback on Face Mites
54:28 to 55:39
Sharing listener thoughts and feelings about Demodex mites after the discussion.
“Are there predators that gobble these things?”
Listener Engagement and Questions
56:03 to 56:34
Learn about how listeners can engage and share their questions with the show.
“I love opening my email in the morning and seeing all the incredible diversity of curiosity and questions and wondering and joy.”
Listener Engagement and Questions
58:38 to 59:05
Learn about how listeners can engage and share their questions with the show.
“Maintenance fee, overdraft fee, minimum balance fee, maximum balance fee.”
Transcript
Automatic transcript. May contain errors.0:00This is an iHeart Podcast. Guaranteed human. Introducing the all-new Mazda CX-5. Featuring more connection. Hey Google, where's the nearest Pilates class? Safety that has your back. More discovery on the scenic routes. More passion in the details. And more control in changing weather. The all-new Mazda CX-5. More to move every side of you. See it in five films at mazdausa.com slash five sides. Google is a trademark of Google LLC. Sequences shortened and simulated. This July 4th, come celebrate at America's Block Party, hosted by America 250. America's Block Party is a can't-miss 4th of July concert happening at the Los Angeles Memorial Coliseum.
0:44Experience music performances by major artists, patriotic tributes, and the kickoff to Giving 4th. Helping to make July 4th the largest day of giving in American history. It's more than just fireworks. Join this landmark celebration and get your America's Black Party tickets now for$17.76 at America250.org. Hey, everyone. It's Cal Penn. I'm inviting you to join the best sounding book club you've ever heard with my podcast, Earsay, the Audible and iHeart Audiobook Club. Every episode, I nerd out with amazing guests and dive into the best new audiobooks available on Audible. It's the book club for your ears.
1:24Listen to Earsay, the Audible and iHeart Audiobook Club on the iHeartRadio app or wherever you get your podcasts.
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2:31One mom gives birth to two species. Hit the news today. Evolution, you're crazy. That's all I have to say. Do physicists see the universe in their mind's eye? Or is it easier to understand it if they're mentally blind? Mites live on your face and mate there at night. Why would evolution do that. It's just not right. Whatever questions keep you up at night, Daniel and Kelly's answers will make it all right. Or it'll creep you out even more. Welcome to Daniel and Kelly's Extraordinary Universe.
3:19Hi, I'm Daniel. I'm a particle physicist, and I think the universe is beautiful and creepy. Hi, I'm Kelly Wienersmith. I study parasites and space, and I think the universe is also beautiful and creepy, and sometimes creepy is beautiful, and it's all complicated. Have you met a parasite, Kelly, where you're like, that's too gross. I wish this didn't exist in the universe. Or can you find some beauty in every single wriggly, crawling, disgusting thing. I can find some beauty in everything, but I would rather not be in the room with Ascarus lumbricoides. It's a really long, really thick nematode.
4:01It really grosses me out. And when we talked about Screwworm a couple weeks back, maybe a couple months back now. I'm still scarred from that conversation, yes. Well, I looked at the photos and that was - Don't do that, people. Yeah, no, nobody else do that. We actually had a listener write us to say they did that. And they were like, I should have listened to you when you told me not to. I have not Googled screw worm. And I think I protected my mental health for that reason. Yes. Do not Google screw worm. It is super gross. So yeah, there's some parasites that I don't want to be in the room with.
4:31I once watched a presentation. I was studying a parasite that lives on the brains of California killifish. And so I spent like literally all day working with brains. But then I was watching an anthropology talk. and they went to a country that was like selling monkey brains. And there was a table filled with monkey brains. And I was looking at just the picture and the room started to spin. Whoa. And I was like, I'm going to throw up. And I was like, but I can't have everybody see me throwing up over brains. I work on brains. And anyway, I like just kind of looked down and hoped nobody could see me.
5:03And I managed to get through it. But it's weird, the things that set us off. The universe certainly sets us off. And I have the same kind of reaction to astrophysical stuff. On one hand, a supernova is amazing. On the other hand, it could sterilize a whole portion of the galaxy with incredible radiation. It's terrifying. The universe is beautiful and incredible, but also violent and destructive and crazy. So it is an extraordinary universe we live in, isn't it? It is. And it's also, I got to say, a confusing universe we live in. And that kind of brings us to our first question, which was really hard to unpack.
5:42This question was an amazing question from a listener, Jamie, who often writes us and sends us articles to be like, does this make any sense? And it's always fun to dig in. And this paper was particularly fun. So the headline is, One Mother for Two Species via Obligate Cross-Species Cloning in Ants. Well, one mom giving birth to two different species? I thought that was impossible. Anyway, let's hear Jamie's question and then dig in. Hello, professors. This is Jamie Pfeffer from Westfield, New Jersey. I would be grateful for your help understanding an article that I read in the New York Times.
6:24It reports on a study in Nature where scientists said that queens from one species of ant produced male offspring of a different species. The scientists then said that it's like a human having chimp babies and then using the babies as a source of sperm for giving birth to human chimp hybrids as a source of labor. What on earth is going on here, please? It sounds like a chapter from one of Professor Kelly's books. Thank you very much. All right, Kelly. So set us up for why this is a fascinating question. My understanding of what a species means is that individuals can mate and give birth to like live offspring that isn't sterile.
7:06And so how can you give birth to two different species? How is that possible? Yeah, it's crazy, right? So, okay, so you can get like a donkey and a horse. They can mate together and make a mule. and the mule is sterile. And so you can get like pretty distantly related species that mate and produce something different. Like for example, my dog has Chihuahua and German Shepherd ancestry and nobody knows how that happened. And I also won't suggest Googling that, but it did happen and he exists. Yeah, yeah, yeah, right. Don't think too hard about it. But so those are different breeds, not different species.
7:43And so the equivalent here would be like, you know, so I gave birth to two human children. It would be like, I gave birth to one human children. And then the next one was a chimpanzee. And that's confusing and unexpected. I mean, you always expect every child is going to be different, but not that different. That's right. That's right. That's pretty different. And the species, so we're talking about ants in this example. And species one, this is the species that gives birth to two species. She, the queens, not only give birth to their own species, as you would expect, but they're also able to give birth to males of a different species that they've been separated from for five million years.
8:26Wow. All right. So this is like dogs give birth to dogs and occasionally a cat. Yes, right. I mean, I don't know how long dogs and cats diverge. That's probably more than five million years. But yes, your point stands. And so, okay, so here's what's happening. So first, ant mating systems are crazy. And we're not going to go into loads of detail because it's super complicated. But what you need to know is that females are diploid. So what that means is that they have two sets of chromosomes. Just like humans, we have two sets of chromosomes. But to make males, they only have one set of chromosomes.
9:04So a female doesn't have to mate with another male if she wants to lay dude eggs. She just takes one set of her chromosomes, sticks them in the egg, and now you've got males. So she doesn't have to mate. She can make males on her own. But to make a female, she needs a contribution from another member of her species. That's right. So to make a female worker, she needs to mate with another male. But having these complicated relationships between the parents and the kids, doesn't that mean that the siblings' relationships are complicated and your evolutionary interests are intermingled in complicated ways?
9:37If I remember, like ants have really complicated sibling math. Yeah, they do. Okay, so the bottom line is that the sisters share about 75 % of their genetic material with each other, whereas usually sisters share about 50%. So like human sisters share 50%, you're saying? That's right, yeah. And ant sisters share 75%. And we think that this plays a role in why ant colonies work so well together. So you can think of ant colonies as like a super organism. You've got the queen who's laying a bunch of eggs, and then all of the females work to support the queen. And you would maybe not expect such selfless behavior unless individuals were super closely related to each other, which means that when the queen is making a lot more babies, they're essentially making individuals who are very genetically similar to you.
10:26And so from a genetic standpoint and from an evolutionary standpoint, this is great news. So maybe you're willing to not mate because your mom is making so many super genetically related sisters and it's awesome. Does that kind of make sense? Mm-hmm. That makes sense. Yeah. Okay. So that explains like how the siblings are related to each other. Why do we need to understand that to understand how you can give birth to another kind of species? Okay. So the thing that you want to know is that this ant that was all over the news recently, when she's giving birth to a new species, she's giving birth to sons in particular.
10:59Okay. And so here's what happened. If you're in Europe and in Asia, you will find these two species of ants. One of them is called Mesor Ibericus and one is Mesor Structor. But we're never going to keep those straight. So I'm going to call them species one. That's Ibericus. and species two structure. All right. In part of their range, they overlap. And in part of their range, they don't. So there's some areas where you just find species one, some areas where you just find species two, and some areas where you find colonies of species one and species two. In addition to all of the ant reproductive weirdness with the females being diploid and the males being haploid, this system has another weird trait, which is called sperm parasitism.
11:48So here's what happens. The workers in the nest are females, but instead of mom mating with a male of her species, mom mates with a male of a different species. What? Right. So they're closely related enough that they can still mate with each other, but they produce, I believe, infertile offspring that become workers. And so why would that evolve? The reason we think that that evolved is because, yes, it's nice that all the sisters are 75 % related to each other, but every once in a while, one of the workers will get it in their heads, and I'm being super anthropomorphic here, but they'll get it in their heads that maybe it would be better if they just laid their own eggs.
12:30What? And now you've got a competitor with the queen. But if all of your workers are these hybrids that are sterile, they can't make their own eggs anymore. And so the queen essentially has this extra layer of control over her colony because none of her workers are even able to compete with her. It's just not even a question. Fascinating. Yeah. And so there are a handful of different ant species we know of that do this thing called sperm parasitism, where they make these hybrid sterile workers by mating with males of a different species. And why exactly is it called parasitism? I think the idea is that so for species two, the males that are impregnating the queen, they're essentially wasting their sperm.
13:16So they impregnate the queen of species one. Yeah. And all of those offspring are sterile, so they don't go anywhere. So the males of species two have made this sperm, paid the cost to make it, and it's genetically, evolutionarily not going to end up, you know, contributing to more offspring for them. And when Jamie asked you this question, do you think he knew there was a parasite angle on it? Or is that just like a happy bonus for everybody? I don't know. It might have just been a happy bonus, but I'm excited either way. Jamie knows us pretty well, so maybe this was a gift for me. I didn't realize that even sperms can be parasites.
13:48That's incredible. Oh, no, no, no. The sperm is being parasitized. Oh, right. Yeah, yeah. So the queen is essentially, like, extracting the sperm for her own purposes. Wow. But not benefiting species, too. Is there an evil cackle that happens along the way, you think? Eee-hee-hee-hee-hee! Because, you know— Whoa! Well, no, but they're little ants, so it's got to be a little high-pitched voice. Try that, Daniel. I can't do that. I can't do that. And I, eee-hee-hee-hee-hee-hee-hee! That's as high as I go. Okay, well, all right. So that was amazing. That's already weird, okay? But so for species one, it has now actually become a requirement that the queen mates with another species.
14:28She can't produce these workers anymore unless she finds species two, males. The thing you thought you were going to do just once turns out to be a habit, and then now you can't live without it. I know. That's right. We've all been there. And so for me, it's coffee. For other people, it's sperm paratacism. That's right. That's right. To each their own, right? So, okay. So you might remember that I told you that there are areas where you only find species one or you only find species two, right? So if species one has to mate with species two, how does species one manage to persist far away from species two?
15:09Yeah. And there's one spot where it's known that there's a thousand kilometers between the nearest species one and species two nests. All right. So there's no queens of species two in the area. But if you find a species one nest and you dig it up, you'll find that there are still hybrid individuals in there. So there's still the hybrid workers. And so the question is, how the heck is she managing to produce these hybrids when there's no males of species two around? The answer is going to be that she makes species two males, which is crazy right so let's go through the process that the scientists went through to sort of study this so first they opened up species one nests and they looked very carefully at everybody who was in there in an area where you shouldn't find any species two and they did find some species two males in the nest and they were like okay that's really weird and so then they looked at the genetic information inside of species two, and they found that species two had mitochondria from species one.
16:16And if you know anything about mitochondria, you might remember that mitochondria are only inherited from mom. So that means that these species two males must have come from a mom of species one because they've got her mitochondria. And they went over to areas where you find species two normally, like in their own sort of colony. And they confirmed species two males usually have mitochondria from species two moms. And so this was weird. So you can tell the difference between species two males that come from species one or species two by their mitochondria. Yes. Wow. Yeah, very cool. But they wanted to make 100 % sure that the queens were the ones who were laying the eggs that had the males.
17:02And so they took queens and workers and they brought them into the lab. And some of the workers that they brought into the lab, these were from species one. They went ahead and they did lay some of their own eggs. And what they found was that 9 % of the eggs made by queens of species one produced males of species two. Right. Super weird. And when the workers of species one made some eggs, none of them were species two. It's just the queen who's doing this. Okay. So then they monitored a colony that they brought into the lab for a year and a half. And they found that the mom produced species one and species two males.
17:43They both survived to reproductive age. And they looked genetically and they confirmed, okay, one queen is definitely making species one and species two males. How is she doing that? Yeah. So one possibility here is that a lot of invertebrates are able to store sperm. So you can mate with a male and a couple months later, you can be like, oh, I'm going to take that sperm that I was storing and now I'm going to fertilize my eggs. And even though there's no males around, I can go ahead and have some extra babies. I didn't know it lasted that long. I thought it had a short lifespan, like 24 hours or 48 hours or something.
18:20I don't know exactly how long it is, but it's more than 24 or 48 hours. But by having them in the lab for 18 months, they were able to like pretty conclusively say, okay, the females probably aren't like flying a thousand kilometers to go find a species two male mating with him and then coming back. Like she's been in the lab the whole time. Or maybe they're like actually aliens and they have wormhole technology and they're like teleporting over there. That's right. Not a hypothesis they considered? No. You know, they didn't have a physicist on the team probably. I know that you always need a physicist, right?
18:52Maybe. Maybe. Maybe. Oh, you're not even going to agree with me on that one, huh? Yes. Hedge your bet on that one. All right. That's fine. Almost certainly. At least we should consider having a physicist on every project. Sure. Right. And are you going to consider having a biologist on every project to make sure you all stay down to Earth? I already do. Oh. I already do. Of course. Of course. Okay. Okay. All right. So they saw this essentially happen in the lab and controlled conditions. So they knew that she was actually generating species to herself. Yes. Right. They also looked at like genetic diversity of species two males in their native range and in these species one nests.
19:30And they were very low diversity, which you would expect, you know, if there was something weird happening and the males were just like a very small subset of their genes were being passed through species one over time. So here is what they think is happening. Females are somehow cloning males. And all cloning means, and you might remember this from a past conversation where we talked about cloning, like in our episode about the dire wolf that was made by Colossal. So essentially what you do is you take an egg and you like extract the genetic information from the egg, except you can leave the mitochondria in there.
20:06And then you put new genetic information into that egg. And then what hatches is the species or the individual associated with the new genetic information. Does that make sense? So somehow the females seem to be taking genetic information from species two, plopping it into their own eggs and producing species two males. They don't know exactly how that's happening. But the way that it could work in theory is that you've got a queen from species one in an area where the species overlap. She mates with a male from species two and stores that sperm. Mm-hmm. She migrates away from the area where their species overlap and goes and starts her new colony somewhere completely different.
20:49Mm-hmm. She uses that sperm to make males, and then she mates with those males to get her hybrid workers. Mm-hmm. That's pretty icky, though. She's, like, mating with her own sons. Yeah. No, I mean, nature has a lot of uncomfortable stuff happening. I'm sure we can find some beauty in that also. Nope. And so, nope. Moving on. And so, hard no. So, okay, so she's got, she can mate with these males that she made, and now she's got her hybrid workers. But when it's time to make a queen, a new queen, she can mate with the other males that are of her species. And then those queens can mate with the males of species two that are already in the colony with them.
21:33They can acquire that sperm and then they can bring that sperm with them even farther away from the initial area that they lived. So even farther away from where you usually find species two. So this is a mechanism for extending your colonies beyond the boundaries of species two. They like need species two, but it's not always available. So they evolved this mechanism to basically cut them out of the loop and make them themselves. Right. Yes. And then they also have this amazing ability to, like, instead of combining genetic information, they just take the male's genetic information and, like, and clone them.
22:08Incredible. Which is totally crazy. And to be honest, the authors were very clear, we do not know the mechanism to explain what's happening here. And so this is just, like, a hypothetical. Wow. But they compared it to domestication. It's kind of like domesticating species, too, and sort of taking it with you for your own purposes. And I'm not quite sure that I buy the comparison, but it's an interesting way to think about it. Yeah, that is fascinating. They're sort of raising it and co-opting it for their own purposes in that sense. But when we domesticate cats, there's no like interbreeding. I mean, not usually that I'm aware of.
22:40Oh, more absolutely not okay. I mean, when people say cat lady, I don't think that's what they mean, right? Oh, gosh. Not safe for work. So the authors propose a new word, changing the subject. The new word is xenoparis, meaning they, quote, need to produce individuals of another species as part of their life cycle. Wow. Xeno means like strange or different and parity means like to give birth. So anyway, giving birth to something different. So does this mean we should, again, broaden our concept of what a species is, that the lines are even fuzzier than we thought before, that biology is amazing us at how messy it is, again?
23:17So let's hold that answer because I am working on a whole episode on how do you define species and all of the weird things evolution does that makes our job really difficult. It's going to be like a philosophical discussion, which I think will be right up your alley. We love it. Yep. Yeah. Yes. So tune in for the answer in a future episode, and let's see if Jamie feels like I managed to figure this paper out. Wow. All right, let's hear from Jamie. Thanks, Jamie. Thank you very much for explaining the article. I'm glad there was at least some form of parasitism in there for Professor Kelly. I look forward to your episode on defining a species.
23:58A story like this makes me wonder if maybe our categories are too rigid or perhaps they don't apply to all creatures equally. Thanks, though. I'm really grateful for the explanation.
24:27performances by major artists, patriotic tributes, and the kickoff to Giving Fourth, helping to make July 4th the largest day of giving in American history. It's more than just fireworks. Join this landmark celebration and get your America's Block Party tickets now for$17.76 at America250.org slash LA. Introducing the all-new Mazda CX-5, featuring more connection. Hey, Google, where's the nearest Pilates class? Safety that has your back. More discovery on the scenic routes. More passion in the details. And more control in changing weather. The all-new Mazda CX-5. More to move every side of you.
25:09See it in five films at mazdausa.com slash five sides. Google is a trademark of Google LLC. Sequences shortened and simulated. Hey, it's Ryan Seacrest for Jewel Osco. Earn four times the points on your favorite brands now through July 28th on eligible items like Pantene moisturizing shampoo, Gillette razors and refills, Secret clinical strength deodorant, herbal essences hair care, old spice deodorant, Pampers swaddlers diapers, and Crest Clean Breath toothpaste. Enjoy savings on top of savings when you shop in-store or online. For easy pickup or delivery, restrictions apply. See the website for full terms.
25:43Eczema is unpredictable, but you can flare less with Epigliss, a once-monthly treatment for moderate to severe eczema. After an initial four-month or longer dosing phase, About 4 in 10 people taking EBCLIS achieved itch relief and clear or almost clear skin at 16 weeks. And most of those people maintain skin that's still more clear at one year with monthly dosing. EBCLIS, LibriKizumab, LBKZ, a 250 milligram per two milliliter injection, is a prescription medicine used to treat adults and children 12 years of age and older who weigh at least 88 pounds or 40 kilograms with moderate to severe eczema.
Read the full transcript
26:13Also called atopic dermatitis that is not well controlled with prescription therapies used on the skin or topicals or who cannot use topical therapies. EBCLIS can be used with or without topical corticosteroids. Don't use if you're allergic to EBCLIS. Allergic reactions can occur that can be severe. Eye problems can occur. Tell your doctor if you have new or worsening eye problems. You should not receive a live vaccine when treated with EBCLIS. Before starting EBCLIS, tell your doctor if you have a parasitic infection. Ask your doctor about EBCLIS and visit ebglis.lily.com or call 1-800-LILY-RX or 1-800-545-5979.
26:53All right. So from ants to ant fantasia, which I reliably produced incorrectly, I'm sure. Me ouch on that one there, Kelly. All right. So we are answering questions today. We love getting questions from listeners. If you have a question about the nature of the universe or really anything about this beautiful, incredible, disgusting cosmic violence that we have and that we live in, please write to us to questions at danielandkelly.org. We will get back to you. And here's a question about visual imagery in the mind and how it enables or disables people to do physics. Hi, Daniel and Kelly. I recently found out that I have a trait called aphantasia, which is the inability to consciously pull up visual imagery in my mind.
27:43I do dream though, but finding out others can picture an apple in their head with their eyes open or closed was mind-blowing. And I've gone most of my adult life without even knowing this. Imagine my continued surprise when I discover that it's not limited to visual information, but can also include auditory, smell, and even taste. I enjoy reading sci-fi and fantasy, but my experience and your experience must be worlds apart. And that leads me to my question. As a physicist, how do you use imagery on a day-to-day basis? Are you writing equations on a chalkboard? And if so, are you holding the chalk?
28:25Thanks so much. Oh my gosh, this is such a fascinating question. And this question reminded me of Temple Grandin. So when we got our son's autism diagnosis, I read every biography I could find written or autobiography written by someone who's autistic so that I could try to understand like what his life would be like. And I guess Temple Grandin has this amazing ability to sort of imagine what it's like to be. So she works with livestock and tries to create ways to make their lives better and to have more humane practices. And she's amazingly good at like envisioning what it must be like to be a cow and what it is that they're seeing.
29:02And she clearly can imagine things way better than I can. And it sounds like this listener is on the other side where they're able to envision even less than I can. And I think this spectrum is totally fascinating. It is really amazing. And it's something we only understood like in the last 10 or 15 years that there is a variation between people and their mental imagery. Essentially, we've been communicating with each other about this kind of stuff for thousands of years and not realizing that we're having very different experiences internally. And I read this excellent article in The New Yorker very recently about aphantasia from late October.
29:40I really recommend it. And it begins with a story of a physicist who in his late 30s or early 40s finally realizes that when everybody else is talking about having images in their minds, they're being literal about it. He thought forever that everyone was just sort of like using metaphors. Like, I mean, you say you're thinking about that, you're seeing that in your mind, but you're not literally like seeing it, right? And it was only like recently the dude is like totally grown up when he realized people are being literal, that some people can close their eyes and imagine an apple from yesterday and like see it be green and shimmery and, you know, really visualize these things.
30:21He thought everybody was being figurative. What do you think it would be like to realize that as an adult? I mean, I think animal behaviorists think about this kind of stuff all the time. Like, you know, that animal can do something I can't. But it must have been a crazy moment to realize. Yeah, well, I think everybody is a little different. And as you're growing up, you discover like, wow, everybody thinks that swimming is fun and I hate the beach or everybody else loves chocolate, but I think it's gross or watermelon tastes like cilantro. So it's not unusual to find something that makes you different.
30:51But it is amazing how such fundamental parts of what we think of the human experience can be different from person to person. And, you know, this is a question like philosophers have been debating for thousands of years. Like, what is it like to be a bat? Do we see the same color red? And so it's sort of incredible that it's only recently people have been studying this in detail. And this article goes into the history of the study of it, which is only about 150 years old. There's a guy, Francis Galton, who's also sort of a famous eugenicist, did some early research and found a bunch of examples of scientists who, he says, quote, have feeble powers of visual representation.
31:31So scientists in particular tend to not be able to imagine things in their minds, which I think is the impetus for today's question. And that's surprising because it feels like visual imagery is so important to physics. Think of the story of Einstein coming up with relativity. He says that he was imagining or trying to imagine pulling up alongside a photon. And in realizing that that was impossible, he understood how photons have no reference frame. And Einstein's work is filled with these examples of trains and passing each other in light. And clearly, he's imagining visual situations, right?
32:07And in chemistry, there's lots of examples like how did somebody figure out the structure of benzene? They had like a dream of a snake biting its own tail. It's like very vivid visual imagery. So it's easy to imagine that having vivid mental imagery would be essential for doing science, right? Yeah, but Galton was wrong about a lot of things. A lot of things, a lot of important things. Was he wrong about this too? So we don't have enough data to know. And the feels has really gone back and forth. Like in the early 1900s, the widespread belief among psychologists was that mental imagery didn't exist.
32:46There's a movement of behaviorism led by a guy named J.B. Watson, who says, quote, quote, what does a person mean when he closes his eyes or ears and says, I see the house where I was born? Touching, of course, but sheer bunk. We are merely dramatizing. The behaviorist finds no proof of imagery in all of this. So psychiatrists felt like, no, you're not really feeling these things. You're not really seeing these things, which is bizarre because some of them must have been experiencing it, right? But that was just the movement. Science is weird that way. It follows these trends and these fads and eventually it zigzags towards the truth, but it can go down some weird rabbit holes.
33:24Yeah. And it can get stuck in them for a while. Yeah. And so it was only the early 2000s when a Scotsman had a cardiac procedure. And after that discovered he could no longer picture anything. What? He used to be able to, and then he had this procedure done. And all of a sudden he couldn't have a mental image of his wife's face when she wasn't there. He lost this ability. What was the tie-in with the cardiac procedure? Did part of his brain not get enough oxygen as part of the procedure? Yeah. So he went to a neurologist and this neurologist had always been interested in this kind of stuff anyway, and did a study and showed that part of this guy's brain had been like weakened probably because of this cardiac event.
34:07And he was trying to call these mental images up, but that part of his brain was not activating. So he found the part of the brain that was like activating when other people were making mental images. And in this guy was now failing. And so he wrote an article about it. This is like a new discovery. And then a bunch of people wrote in and they were like, oh my gosh, that describes my experience. And so it turned out this wasn't just like one random Scotsman who had an injury, but it was fairly common. And so he decided to call this aphantasia. Fantasia was defined by Aristotle as the ability to conjure an image in your imagination.
34:42So aphantasia, meaning you can't do it. And Carl Zimmer wrote an article about this in Discover Magazine, which got a lot more attention and a lot more people wrote in. And they were like, wow, this is actually quite widespread. Huge Carl Zimmer fan, let me just say. I know. And I love when science journalism helps propel the science, right? Gets the right attention to it. People are like, hey, everybody should know about this. This is kind of a thing. and a lot of people, it turns out, discover that they have this condition only when reading about it or hearing about it described on the radio.
35:16Their whole lives, they had heard people talk about picturing things or imagining things or visualizing beaches or whatever, and they just assumed that these were idioms, that they were kind of being hyperbolic, they were exaggerating really, that they weren't really seeing it. And only when hearing this described, that this was a condition that you could have, that they'd been deeply and profoundly misunderstanding everybody else's experience. I wonder if they're more likely to doodle. Because if I'm trying to keep track of things in my head, but I couldn't do that, I feel like I'd want to doodle it out on paper to keep...
35:49Anyway, I'm getting... This is amazing. No, it's fascinating. And in the article, they interview some artists. And there are some artists who have a Fantasia and they hear other artists say like, the picture didn't come out as crisply as it does in my mind. And these artists with the Fantasia are like, what are you talking about? And there's the opposite condition called hyper Fantasia, where you have like exceptionally detailed mental images, which sounds awesome. But some people describe it as like graphic and inescapable. You know, where you like if you watch a horror movie, you just like can't escape having those terrible scenes in your mind.
36:25You know, we don't fade the same way we do for others. I can totally imagine that not being good. like those pictures of screw worm that I looked at, I've kind of forgotten them. It would be awful if I could still see them right now. Yeah. Somebody with hyperphantasia said that, for example, if somebody just like mentions skateboarding, then he gets like an avalanche of vivid memories of every skateboarding experience he's ever had being in like stuck in virtual reality and having like a three 60 degree video of a thousand skateboarding experiences forced on you. So they sort of at the mercy of what people say because his, his brain is so visual.
37:00That feels like two problems though. Like being able to really visualize something and having too many memories coming in. That seems like two things. Yeah, exactly. So this is something we're still understanding. It's like, it's the brain, so it's complicated. But it's amazing to me that it's only recently we've even recognized that this is an issue, that there really is a difference. And there's this meme that's going around now online. You've probably seen it, which shows like a person with like a crisp image of an apple in their mind and then gradations all the way down to a person with no image at all.
37:30And you should look at that and you should ask yourself, what do I see in my mind's eye? And there really is a huge spectrum. There are people who just cannot visualize stuff in their brains and people can have exceptionally crisp photo quality images in their minds, which might feel weird to you as well. And I thought about this myself and I'm a very visual person. I can really imagine a crisp apple, not quite photorealistic, but with a lot of detail. How about you, Kelly? What kind of images do you see in your mind? I think I'm somewhere in between. Definitely not photorealistic, but I can see stuff.
38:00And this is fascinatingly connected to thinking about science because we talked earlier about how it might be really important to have these visuals in your mind to do science. But Oliver Sacks did this fascinating experience, which you'd love, Kelly, because it involves self-experimentation. He had almost no mental imagery, but then he decided to take heroic quantities of amphetamines. And while he was doing this, he could see images in his mind. It activated this part of his brain so he could do it. But then he could no longer think about abstract stuff. So it was sort of a trade-off. So it might be that people who are exceptionally visual can't think as abstractly.
38:38And people who think better abstractly can't think as visually. And so to the question, what's crucial for doing physics? It might be that not being constrained by visual imagery makes you better thinking about complex things like 11-dimensional manifolds that you need to solve string theory. Maybe being unshackled from the reality of our intuition, the dominance of our physical world and its implied limitations makes it easier to think about complex numbers and all sorts of crazy things, which a lot of us find counterintuitive because we don't see them reflected in our reality. And so I think the answer to the question is that there's a whole spectrum of experience and there's different kinds of physicists.
39:22Like for me, when I think about physics, I think very geometrically. Even if we're talking about weird abstract math, I see it in my mind as shapes, like fitting together or not fitting together, or clicking or pulling on each other. When I think about quantum fields, it's very visual and geometric. And I always struggled with equations. I can do the math, obviously. I know how to manipulate equations, but I don't think in terms of equations. I don't look at an equation and understand intuitively. I have to translate it into geometric concepts in order to understand how the pieces are pulling on each other and how they interplay with each other.
39:57So I think there's probably a whole different spectrum and different kinds of brains are good at different kinds of things. And I'm glad that we have a diversity of brains in physics and in biology and in the world. Absolutely. But now you've got me wanting a survey of different fields and having them do that, that like gradient of photorealistic apple to like hazy apple and seeing if different kinds of fields have different average scores on that test. Yeah, right. It would be fascinating. exactly but it's it's good that we have all these different kinds of brains i wonder how hereditary it is you know it's like if you have apple pictures as parents does that mean you can picture apples and if not and how random it is anyway it's amazing the way the world is and the way we image it and how bad we are at understanding other people's internal experience and what else are we not understanding because we're using these clumsy words even within our own species right Right.
40:52And then you try to figure out what's happening with another species. And it's amazing we understand anything at all. Yeah.
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43:45Okay, we're back and we're answering questions from you, from listeners just like you, who had a moment of curiosity that they couldn't scratch themselves. And so they wrote to us and we are here to scratch that itch. Well, and speaking of scratching, we're going to talk about little mites that live on your face. Oh boy. All right. So Lunar on Discord had this question for us. Good morning, Daniel and Kelly. How are you? This is Lunar from Discord. So my question is pretty simple. Why does a thing like Demodex follicularum actually exist? I understand nature is strange and life is beautiful, but why do these things exist?
44:24Why do I now know that there are itty bitty little mites living on my face and getting jiggy with it all through the night? It kind of sort of makes me want to bathe in pesticide. So can someone put my mind at ease and just let me know, let us know, let the people know that these things aren't causing us any harm and they might just very well be living out their best life. So what's up with these little face invaders? Thanks. You know, I'm a big believer in scientific education and knowing stuff, but wow, I'm not sure I really want to know about all the gross stuff that lives on my face. Too bad.
45:04Here it comes. Okay, so Demodex is a genus of mites, and mites are related to arachnids. So they're related to spiders and ticks, but like they're their own sort of thing, and they live on our faces. There are two species that you tend to find on your face, Demodex follicularum and Demodex brevis. Follicularum lives in like our smaller hair follicles and like your eyelashes and stuff. And so your hair follicles are like, you know, the holes where the hair shaft sort of goes in there. They live inside of them. They're a social species, and they eat skin cells that they find in there. The other species usually lives near oil glands and stuff in hair follicles also, and they're eating, like, the greasy stuff that our oil glands make.
45:50So does that mean that they're really small? They're, like, smaller than the width of a hair, so they can, like, crawl into these follicles and have a snack? Super tiny. You can't see them. They're less than half a millimeter. The brevis one is particularly small. So without a microscope, you can't see them. You can't feel them. But if you have clear visual imagery, now you're thinking about them and you're imagining them crawling all over your face. Oh, but they save the crawling over your face for nighttime. So right now they are in your pores eating their dead skin buffet and their grease buffet.
46:23All you can eat dead skin buffet. Woo-hoo! But when you fall asleep, they come out of your pores and your follicles, and they mate on your face. They mate on your face. Wow. They mate on your face. I guess for some people, that's good news, you know, to eat your own. I don't know. There are so many jokes we could make here, but we're not going to because you're already imagining them, so we don't have to. That's right. That's right. Okay, so we had a listener ask us in the past, how do pinworms know it's nighttime? How do face mites know it's nighttime? I looked this up. And first of all, it turns out they can detect light.
47:03So probably even from inside your hair follicles, they can tell if the lights are on or the lights are off. So they can just like notice it's getting dark and they're like, ooh, it's time for some romance. That's right. That's right. Somebody's turning down the lights, putting on the algorine. That's right. I've been really trying. I'll stop. So we are keeping that, Matt. That's gold. Oh, no. All right. OK, so it could be the light, but they also and this is sort of interesting. A couple episodes back, many episodes back now, maybe we talked about circadian rhythms and we talked about how circadian rhythms are this like interplay between proteins that are made by your genes.
47:40And some of them are made more at night and some of them are made more during the day. And they help you keep these 24 hour cycles. Somebody looked, a group of researchers looked at the genome of demodex that live on our face, and they're missing a lot of the genes that you'd need to make the proteins that make circadian clocks. And so they think that actually the mites are sort of bathed in the melatonin that we make. And so instead of trying to do their own circadian clocks, they're like, oh, the human is oozing melatonin. Time for them to go to bed. Time for me to get it on. And so they don't need to do it on their own.
48:16Anyway, that's just a hypothesis. But there are other parasites that sort of cue into what host hormones are doing and use that information for their own purposes. So they don't have their own internal clock, but they have all these external triggers that tell them, like, when it's out green time. Exactly. Exactly. Can't get enough of your face, baby. Oh, gosh. All right. That's enough. That's enough. Okay, so where do your mites come from? This is an interesting question. So actually, most people by the time they're adults have mites. Right. And a lot of kids have mites too. And so somebody did a study to try to figure out.
48:54So imagine that you have a family living together. You have two moms and two kids. The two kids, if they were breastfed by one of the moms, they are much more likely to have her mites than the mites from the other mom. because another place where you find these mites is on nipples. And so the mites, you know, probably like jump off the nipples and onto your face. And so you get your face mites from your mom. And if you were to look at the other mom in that couple, her face mites probably are more like her mom's face mites. Does that all make sense? Yes, exactly. Something else you can thank your mom for.
49:33And are these bad in any way or are they good or are they just totally neutral? Yeah, good question. So other species have demodex mites too. Some of them can be sort of parasite-like, but it looks like our mites are usually not a problem. And maybe they're sort of evolving in a trajectory away from parasitism. But for most of us, we've got these mites on our face, we'll never notice it. But if you end up being immunocompromised, sometimes you will start having problems with these mites. If you're immunocompromised, it seems like they're able to reproduce even more. And if you have rosacea, they can make your skin feel even more uncomfortable.
50:10They don't cause the rosacea, but if you already have like a problem with your skin getting irritated, having a bunch of mites on your face is probably not gonna help anything. They also contribute to what I think is called, here's another opportunity for me to mispronounce something. Love it. Blepharitis? Have you heard of blepharitis, Daniel? Never heard of it, or maybe it's not pronounced that way, but it doesn't ring a bell. Okay, it's probably not pronounced that way. But so it's essentially like you get this like crusty stuff on your eyelids. And they think that the mites living in your eyelashes could be contributing to that.
50:46And this tends to particularly be a problem in elderly folks. And so, you know, this also could maybe be an immunocompromised sort of situation contributing to it. But for most of us, the mites aren't bad. It's amazing. You can have this whole ecosystem living on your face and snacking on your skin and not really hurting you at all. They're just like friendly neighbors. Yeah. How do they benefit? Do they help clean stuff up? Like all this dead skin, would it be bad if you didn't have somebody munching on it? No, I don't think so. I didn't come across anything saying that the mites are helpful.
51:16And, you know, especially these days where we've got like soaps to wash our face, we've got ways to exfoliate. I don't think we really they're not really contributing to the like cleanliness of our faces. And you see similar things happening in dogs. So dog species have their own demodex mites. And sometimes you'll get bald patches on puppies because their immune systems aren't good yet. They're just developing. And those bald patches will be areas where the mites are sort of getting out of control. But if you just wait long enough, in a lot of cases, it'll clear up because the puppy's immune system will mature and they'll get those mite populations back under control.
51:50And that patch will sort of grow back in again. But Daniel, I bet you are wondering, does Demodex poop?
52:01I was wondering if we could complete the DKEU bingo and have either poop or cannibalism. So which way are we going? We're going poop. All right. I didn't find any evidence that they eat each other. And so for a long time, the going knowledge was that Demodex doesn't poop. They store up all of the waste that they make. They only live about three weeks. And so actually, if you live to be about 73 years old and your Demodex each live three weeks, you're probably host to something like 1 ,200 generations of mites throughout your life, which is just crazy. I have an input-output question. They have inputs.
52:40Yeah. They have no outputs. Are they just getting bigger and bigger and bigger or what's going on? Well, so the idea was, you know, three weeks is not a long time. They just, they store it. They do get a little bit bigger. And then when they die, they just kind of like, you know, release everything. So they just like die in a big poopy corpse in your face. Yeah, that's right. That's right. But actually some very good sleuthing in 2022 with some great photos found an anus. Yay. This is why you fund basic science, people. I want to use very powerful telescopes to look for tiny anuses. Well, tiny anuses have been found.
53:19They also found a tiny penis on their head. So that's where the males have their wieners. So anyway, all kinds of important information. But we haven't actually answered the listener's question yet, which is. Oh, yeah. I've lost track. What was the question again? Why? Why would you have this horrible thing? And I actually, I feel like it's obvious. Like we are a super abundant species. We are very close to our offspring. You know, sometimes they sleep next to us. We breastfeed them. It is very easy to imagine transmitting this, you know, parasite or symbiont, if it's not bad for us, like this critter from one organism to another.
54:01We are a super abundant species. And, you know, they're so tiny that we don't even know they're there. So we're not attacking them or anything like that. I mean, it seems to me like we are a great ecosystem for a little critter like this. And so, you know. So why not, basically? Yeah, that's right. Yeah, evolution fills any niche that it can find that it's got a path to. And our faces were one of those paths. And is there like a whole ecosystem there? Are there predators that gobble these things? Or do they live a predator-free lifestyle? I don't know. Oh, that's a good question. Because they sound delicious.
54:37Sure. Okay. I feel like they probably have parasites also that infect them or something. Right. Exactly. Maybe they have face mites. Maybe they do have face mites. It's face mites all the way down, isn't it? Oh, my gosh. We figured it out. Yeah. So I didn't find any stories about them having parasites or predators, but I would love to know. And, you know, we are probably their biggest problem when we wash and exfoliate our faces, but they hang in there inside our pores. Well, we have brought you up to speed to the forefront of human knowledge on face mites. Let's check in with our listener and see if we have scratched the lunar's itch.
55:18All right. Hey, thank you very much for that. Excellent answer, Kelly. And I greatly appreciate knowing that these little creatures are just simply getting by. It's still a little bit weird to know that they get up some interesting nocturnal activity. At least someone's having fun. And thank you very much, Daniel. I will never listen to Barry White the same way again without having a certain mental image of little mites and their heads having fun on my face. Thanks a lot, guys. I appreciate it. Keep up the good works. You guys rock. Thank you so much, everybody, for your questions. We appreciate them so much.
55:58There are so many topics that I would love to have the time to dig into. And when you ask about them, I get to. I appreciate you all so much. We do. We love hearing from you. I love opening my email in the morning and seeing all the incredible diversity of curiosity and questions and wondering and joy. We love hearing from you. that makes this podcast a conversation between us and you, not just between me and Kelly. So thanks everyone for joining in. Thank you. Until next time.
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Daniel and Kelly answer questions about birthing multiple species, mental imagery, and face mites!
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