EUVC #280: Tej Panesar, Partner at Prism Ventures on LP investing in life sciences

15 Feb 2024 路 1 h 16 min

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EUVC Episode Notes: EUVC #280 - Tej Panesar, Partner at Prism Ventures on LP Investing in Life Sciences

Podcast Overview

  • Title: EUVC
  • Hosts: Andreas Munk Holm and David Cruz e Silva
  • Description: A podcast focused on the European VC landscape, featuring insights from prominent figures in the industry.

Episode Details

  • Episode Title: EUVC #280: Tej Panesar, Partner at Prism Ventures on LP Investing in Life Sciences
  • Guest: Tej Panesar, Partner at Prism Ventures
  • Focus: Investment strategies in the life sciences and healthcare sectors, with emphasis on LP (Limited Partner) perspectives.

Key Themes and Discussions

  1. Introduction to Prism Ventures
  2. Investment Focus: Institutional investments in life sciences and healthcare sectors.
  3. Strategy: Invests through fund of funds and co-investment programs in best-of-breed funds across the US, UK, and Europe.
  4. Background of Tej:
  5. Previous role as Investment Director at British Patient Capital, investing 拢425 million in UK venture capital.
  6. Built a dedicated life sciences investment program during his tenure.
  1. Transition from Crowdfunding to Venture Capital
  2. Tej's journey from working in fintech startups and crowdfunding platforms to becoming an LP in venture capital.
  3. Emphasis on learning about institutional LP investing through experience at British Business Bank.
  1. Perspective on Life Sciences Investing
  2. Non-Binary Nature: Tej discusses the misconception that life sciences investments are binary (win/lose outcomes).
  3. Investment Strategies:
  4. Emphasizes structured approaches to mitigate risks in biotech investments.
  5. Importance of milestone-based investing.
  1. Opportunities in Biotechnology and Healthcare
  2. Current advancements in biotechnology are creating a promising investment landscape.
  3. Tej notes the intersection of life sciences with AI and machine learning as an emerging opportunity.
  1. Challenges in the Health Sector
  2. Adoption challenges for new technologies in healthcare systems, particularly in Europe.
  3. Insight into the need for VCs to understand regulatory complexities and the slow-moving nature of healthcare institutions.
  1. Portfolio Construction and Diversification
  2. Investment Strategy: Focus on established fund managers (80%) with a portion allocated to emerging managers (20%).
  3. Geographical Distribution: Investments split between US, UK, and Europe.
  4. Importance of diversification in sector focus while monitoring allocations to avoid overexposure.
  1. Importance of Team Culture and Succession Planning
  2. Tej shares insights on evaluating team dynamics and the importance of succession planning in VC firms.
  3. Highlights the significance of having a diverse and effective investment team for long-term success.
  1. The Role of Emerging Managers
  2. Discusses the vital role of emerging managers in the VC ecosystem, emphasizing their ability to access innovative technologies and emerging sectors.

Key Takeaways

  • Investing in Life Sciences: Tej argues that life sciences is a complex and intellectually demanding sector with significant potential for returns.
  • LP Perspective on VC Relationships: Relationship dynamics between VCs and LPs matter; LPs should seek partners who align with their investment philosophies and provide value beyond capital.
  • Future Outlook: Tej is optimistic about the growth potential in life sciences due to demographic trends and technological advancements.

Final Thoughts

  • Tej encourages LPs to explore investments in life sciences, citing numerous technological breakthroughs and the increasing integration of AI in the sector.
  • Advice for Emerging VCs: Maintain stamina during fundraising processes, develop a long-term vision, and self-assess the viability of their strategies.

Conclusion The episode highlights the evolving landscape of venture capital in the life sciences sector, underlining the importance of strategic investments, team dynamics, and understanding regulatory challenges in a rapidly changing environment.

For full insights and additional resources, visit [eu.vc](https://eu.vc).

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Transcript

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0:00Hello, everyone, and welcome to another episode of the EUVC podcast. I'm David and I'm joined by Andreas. Today we're welcoming Tej Panesar. Tej is a partner at Prism Ventures, the UK headquartered institutional investor focused on the life sciences and healthcare sectors, a sector we don't cover that often. So I'm really excited for this one. Prism invests into best of breed fund managers in the US, Europe and UK through fund of funds and co-investment programs. Tej was previously an investment director at British Patient Capital, BPC, a UK government-backed institution very similar to the IES and one of the largest investors in UK venture capital.

0:39While there, he committed拢425 million to venture and growth fund managers in the UK and Europe and led investments into firms like SV Health, Ambienworth, IQ Capital and Don Capital. At Frisbee Ventures, Tej and the team have a wide lens across the life sciences and healthcare industries, but a strong focus on traditional biopharma and your areas like tech bio. If you're listening in and love our show, you know what to do. Drop us a review, follow the pod, and subscribe at eu.vc.

1:23United and determined, we can serve as a model for other regions of the world. The nature of a problem requires a European response. Europe is a story of new beginnings. Let's start acting. In a world where podcasts outnumber humans, we try at EUVC to be mildly more interesting. Tune in at eu.vc to watch this episode instead of just listening. EU.VC, where the extraordinary is just another Monday. This show is not investment advice and the hosts of this episode may be invested in the funds and companies featured. So, Tesh, let's start this thing off as we always do. Tell us your story about how you got into venture.

2:15That's a big question. It's a fairly long and varied journey. So if I start right at the beginning, I grew up in Northern Ireland. I was the son of a senior surgeon. And that really kicked off, I think, at the beginning, a strong interest in technology in some form or another, or at least created a curious mind. My journey into venture, it really began with my first sort of foray into technology and startups. I started my career at Citigroup within the investment bank, but then quickly joined an internal fintech startup, Orbion. And that was focused on digital trade finance. And then I left with one of my former city bosses to start an online brokerage platform called OnBourse.

3:05That really gave me the entrepreneurial bug. After that, I worked for a period with a boutique advisory firm focused on LBO transactions, but also venture deals. and then had a crazy idea, had been a real estate investor in London, had lots of friends in Eastern Europe and decided to go off to Poland to start a real estate company and fund. Ran that for 10 years, so had a sort of very much a real estate focus for about a decade, but was lucky enough to be part of the sort of burgeoning tech community that was going on in Krakow at the time. And that's since grown from strength to strength. And so I was a part of that as an investor and advisor appearing at events.

3:51And it was really through that community that I then, as I was coming to the end of my time at Poland, I met the US crowdfunding platform at an event in Krakow, the firm Indiegogo. And indirectly, that led to me joining the equity crowdfunding platform in the UK, Crowdcube, when I returned in 2014. I had some options. I could have gone back into the city. But just from my background, I wanted to do something again, more entrepreneurial. And Crowdcube was a great exposure to high growth environments, to VC as well. They're backed by Bolton and Moulton. And while I was there, Crowdcube got me to look at setting up their own venture fund.

4:35And through that met the British Business Bank, some of the team there as a potential LP. And that was really my first exposure to the world of the wacky world of institutional LP investing. And before I knew it, a few years later, I was working at the British Business Bank, later BPC, where I spent five to six years as a venture focused LP. initially focused on tech, but then quickly developed a very strong interest in the life sciences sector, led the institution's deployment in that field, and even got the opportunity to build out a dedicated program, which was the life sciences investment program, the 200 million program focused on later stage UK life sciences, which was a collaboration with the UAE investor Mubadla.

5:24So BBC were an incredible incubator for me, taught me my trade and that interest, they incubated and that turned into a passion and they supported actually the completion of a biomedicine degree while I was there. And by coincidence, I had my graduation ceremony last week. So that was a lot of hard work. I'm glad it's over. But last year, then a German family office reached out to me and said, listen, we really like what you're doing, what you've done at BPC. We're thinking about creating an institutional life science focused program, focused on a global basis, the opportunity set. And that brings me to my current role as a partner at Prism Ventures.

6:11So long and circuitous, but I hope that gives you some sense of where I come from. I've been looking forward to this conversation. We spoke, I guess, six months ago or so, maybe even more. And you're a very, very smart guy. And for that reason, I'd love to ask you to enlighten us on how you look at the different LPs that exist in the world, right? the different classes of LPs, because you've been in many of the different shoes and seen that. So I'd love to kind of ask you to expand on that for our audience and what you'd say that VCs should be thinking about when they're talking to LPs and thinking about their LPs.

6:57We're going to talk a lot more about Prism and what you look for in managers. And that's why I want to start out by just getting you to give us an LP's view on the LP world. so listen i mean as with gp world it's uh it's huge and it's varied and it varies from region to region it varies from lp type to lp type but my initial interaction day-to-day was was with institutional lps and similar to ourselves at bpc they are very very rational actors not to say aren't rational actors, but they very much operate to a process. They very much operate to a long-term strategic approach. And that means, and they have relatively clear criteria, but as always, they can't work with everybody.

7:50And so they have to introduce their own filters. And that's where you see a lot of variability. Some firms, some government investors will tend to entertain everybody. It's part of their mandate. They should talk to everyone. They should give them a fair shot. Other private institutional LPs, they might use the classic VC filter. Can you get through to a senior person? That's your job to do that. They make it deliberately difficult. Others put their representatives out in the market and they're very easy to contact. So institutional world, everyone has a different approach, but the consistency tends to be a framework in the way they deploy capital, a gated approach in the way that they filter the deal flow pipeline, and some kind of reference to a broader strategy in which they triangulate to their opportunities of interest.

8:45Family offices then are a really important element in the ecosystem, but I think that they also have elements of the institutional approach, but they can be heavily driven by the principal or the family involved and their areas of interest. And that's great in a sense, because that gives you a different angle with which to approach an LP. Commonalities in areas of focus, focus on sustainability, focus on interests in life sciences and healthcare. There are common topics of interest potentially. And if you're lucky enough to speak to one of the family members, great, you can quickly, sometimes much more quickly get through to a decision.

9:28And that's very, very helpful. So I think they play an incredibly important role in the ecosystem, typically smaller checks, but my God, are those checks useful for a VC? And then the even more varied world of high net worths who pop up everywhere, are part angels, occasionally will think about taking an LP stake. And they bring something to the table as well for any VC. They bring connectivity in the market. They bring really sensible advice on any of the LPACs I've ever been on with high net worths. They tend to be clear-minded individuals who have a very current view on the market. So generally have always had very good experiences there and so in terms of vcs communicating to all of that it's it's it's you know how long is a piece of string it's it's about really um thinking hard about your strategy and thinking hard even though you know capital is scarce about what kind of lps do you want to work with um because it's going to be a long long-term relationship and uh you know some are more rational actors than others some are easier to deal with than others.

10:42And you want somebody that's going to be value-add to your strategy. So in a perfect world, you'd have maybe a strong institutional cornerstone. You'd have a number of family office checks that are sizable, and they are also going to be patient investors with you. And then you really see what the rest of the mix-up looks like. And that may vary from fund to fund. And you've got to be open to that. You've got to be constantly fundraising, as all VCs are. Your remark about the value of high net worths on an LPAC is probably the first time I hear it, curiously enough. I've had a good experience. Maybe others haven't.

11:22But I guess, as you said, it's such a varied part of our ecosystem. It's like that, that you can have everything, right? It's like working with any angel. That's a very cool insight. Tej, let's move on to the next part of our conversation here, which is, would you show us a pivotal moment in your life and how has it shaped you today as an investor yeah um so i mean i think it'll be a fairly boring answer and a bit repetitive but but really i think in terms of coming to where i am now as an lp and a life sciences focused lp it was i'd had that long and varied career which which i described and i then came to the to the british business bank and began my career as an lp and they were great and recognized something in me that that variety might potentially create a good LP.

12:11And so I had fantastic mentors there, people like Ian Conaty, the new deputy CIO, Catherine Lewis-Latorre, the CEO, and Christine Hockley, who's the MD there. And they were great at sort of nurturing me and supporting my intellectual interests. I think they quickly recognized somebody who has a tendency to follow their intellectual nose. and the life sciences connection quickly came through. And through that, I met my first life sciences fund manager, which was the Dementia Discovery Fund, walked into a room, I have to confess, thinking, oh, is this really going to be a commercial strategy? Had Kate Bingham of SV Health sitting across the table from me and came out of it going, you know, I really like these guys.

13:02I really like the strategy. And so something was in that and it rolled on from there. And then through that sort of exposure to the life sciences sector, as I hope, a sort of a nerd and a technologist, the slow realisation that, you know, where biomedical science is going is incredibly exciting. And the rate of technological innovation that's happening there is simply stunning, both in traditional biotech and other areas like tech bio. And that really led me to where I am today, which is, you know, a hopefully knowledgeable LP with domain expertise in the sector and effectively a specialist LP who has decided that that is the rest of my career.

13:48so eventually found a good home for my skill set but it took some time Tej could I ask you because on the one hand life science is a space where a lot of institutional investors especially private ones say well we don't touch that specifically what you say you're interested about which is the clinical side and also med tech and I think part of it is also there is some serendipity in being an institutional like BIF or BPC and others that allows you to have exposure to that. But I'd love to ask you as someone that was not a life scientist slash healthcare slash drug, whatever, expert, and having that first exposure, how has the journey been into becoming a specialist?

14:39Because that's something that you don't see many people do. And I actually think there's a bit of almost a bad rep to some extent, both on GP and LP world. So I'd love to just kind of get into your brain there of how that journey was. Well, maybe if I address your first point, which is sort of the binary aspects of the sector and that perception, you hear that comment a lot. And my response to that is always, is it? You know, and I think, again, when I first started coming to this journey at the British Business Bank, we used to look at data from the EIF, EIF would put out the Ugly Duck presentation and it kept on popping up these several charts that would say the top three out of the top five funds in our portfolio are life sciences I may be misquoting them but the DPI on the life sciences side is much higher or is somewhat higher point being good returns and counter cyclical good returns and counter cyclical and we were sort of scratching our heads sort of, you know, how can this be?

15:46And the point is, when we came to it as an LP, over time, what I realized was that on the aggregate, it is not necessarily as binary as it might first appear if you were trying to invest directly as a high net worth or a family office in an individual biotech, or it is far less binary than you might think. And why is that? So I think the first reason is I came to realize that the life, you know, venture on the tech side can be very, very variable. And the entry access point can be a mix of things. It might be a technology background, it might be personal wealth that has allowed you to enter this world of VC.

16:30And so you end up with a lot of different types of models. The same is true on the life sciences side. But the one consistency you have is it is just simply an intellectually tough place to enter. And not to say that's not true on the tech side as well, but on the life sciences side, the people that we would encounter were extraordinary within the VC community. Someone might have a PhD in molecular biology, will have gone on and worked in research, will have gone to pharma, may then have gone into the city and spent a time working at an investment bank. And we kept on seeing these profiles of people.

17:11And that was then reflected very often in the strategies. And what we would see firm to firm, while the approach would change firm to firm in life sciences, what we saw was this very intelligent, very risk-balanced way of handling biotech risk and strategies that might have an early stage, more risky components, mixed with a later stage, more easily predictable environment, mixed with other types of strategies like, you know, sort of quasi-structured finance, where assets are taken off farmers' balance sheets and structured within SPVs. And so an incredibly structured approach to VC. And all of this in the backdrop was helped with things like the regulatory environment, where because you effectively have clinical milestones, while yes, they are binary outcomes in theory, what you have then is it structures the way that VCs deploy capital into them.

18:12Milestone-based investing, heavy reserves, an ability to cut the experiment short if it's not working out, if they're an astute enough investor. So on that binary point, I beg to differ. It's true, but it's not entirely true. And so what we found, and this is really the thesis of Prism, is that you have a sub-asset class within venture that is highly performing, has a great deal of consistency, and is technologically incredibly exciting. Before taking us on to the next part of this, I do want to ask you to tell us a bit about, so obviously with the father as a surgeon, there's a personal affinity for a space here, but you haven't spoken too much about the opportunity that we're looking at and why you think that now is an especially good time to be investing in this space.

19:10So I'd love to ask you to just tell us a bit more about that before we get on with everything, because I think it's worthwhile setting the stage for that also, because we have many that listen to an episode like this with that interest saying what's actually going on. Yeah, it's a great question. And it comes down to, you know, what got me excited about this space, you know, five, six years ago. and I you know some people have referred to it as the as the golden age of biotechnology and I and I genuinely feel that and believe that I think we are at an extraordinary moment where on the biomedical research side there are a consistent flow of fundamental breakthroughs that have created an acceleration of modalities and technological innovation such that we are no longer in a world of small molecule medicine and biologics and antibodies.

20:11Now we have added to that within the last 15 years. Cell and gene therapy is a key area of focus, protein degradation, as well as many, many others. So that's on the biomedical side, incredibly exciting. You know, sciences, the scientific researchers are only getting better and better within academia at producing those breakthroughs. But then combined with that, life sciences and healthcare as a fundamentally useful and appropriate use case for technologies like data analytics, artificial intelligence, machine learning in particular. And you look at breakthroughs at teams like DeepMind, dysmorphic labs, you know, really exciting developments and uses of artificial intelligence and machine learning to drive and give an exciting new tool to biomedical research.

21:14And it's, you know, the volumes of genomic data that are being produced now as the cost of sequencing falls is unparalleled. I think I saw a stat a couple of years ago that compared it to being in a few years time similar to the volume of data being produced by YouTube, Facebook and Google put together. I don't know if that's quite true, but it's a lot. And that then is driving this this move towards the potential for precision medicine, which is really this this this loop where you effectively, you know, can afford to sequence my genomic profile. You can perform deep data analytics on that. You have predictive power within computational infrastructure that allows you to say it's possible Tej might or might not develop certain diseases.

22:02You have the monitoring capability to be able to monitor me day to day. You have the diagnostic capability to say, you know, are we seeing signs that this might be happening in him? And then you have the no longer symptomatic treatment of that potential disease, but you have the curative potential of things like gene therapies. And we saw the announcement of the approval in the US and the UK of a therapy for sickle cell disease affecting a huge patient population and potentially curative. plenty of issues around cost and the ethics around that, but an amazing technology that will affect millions of patients' lives.

22:47So for all those reasons, again, a very long-winded answer, but my apologies. But this podcast is dedicated to long-winded. Good, good. A new tail end. Yeah, and I'm afraid I can go on about it forever. But for all those reasons, it fundamentally excites me as a sector. and combine that with some of the comments I made about the VC's battle-hardened approach within the space, not to get caught up in the hype, not to get caught up in the excitement, but to expertly go into that technology equation and extract commercial value. I think it's a super exciting space and I would encourage other LPs to take a look at it.

23:30A hundred percent. So now let's get into our Take a Stand section. Take a start.

23:45So Tesh, I would love to ask you to comment on this quote by our very dear friend Simon Lohman from Cavalry. And the quote is, Europe will not sleep through the next technology wave. And what I mean with that is actually the AI platform shift that we have at the moment. So I love the quote. I think it's particularly astute and it sort of captures the state of play of where we are in European AI, but also beyond the research side, the capital raising ecosystem. So I was lucky enough to work as an LP with groups like IQ Capital. And that really helped me plug into the ecosystem in Europe. And there is a depth and expertise of deep tech investing that I think is very special in Europe.

24:42in a sense that that ecosystem have come through an environment where there wasn't just simply a wall of capital you know pointed in this direction a few years ago so those uh those vcs and those companies have come through with a really lean approach um to to developing their technologies in my own field i mean it's not the first time that that ai has been has promised a sort of new dawn in medicine and innovation in healthcare. We've seen this before, but I think that we have some really interesting combination of factors that are happening, algorithmic advances, improved computational infrastructure, as I mentioned, the explosion in data, in genomic data, electronic health records, and even the increased digitization of of research and lab work across pharma biotech academic organizations so so all of that is coming into play i've seen it through my own studies to a limited extent but but in particular some of the the filtered information we get from the vc community really excites me about what what is happening within uh european ai what are you seeing you put it beautifully when you said the filtered level of information that gets to you.

26:16Because that's exactly how David and I put it as well. Just in a more... That's more eloquent than we would ever say. Yeah, that's more eloquent. You're exactly right. That's exactly it. And that's why I want to ask you this question. Because for me, I am very much seeing this opportunity, right? But I am also seeing definitely a sector that I have found to be crap at doing anything that comes with data and adaptability and moving quickly and so on. So we know how to use a new cancer treatment and get that into the system. But we've been really, really bad. I think that's my take, at least, in the health sector to incorporate this type of technology.

27:04So what are you seeing in that filter in the end? What are the things that you're seeing VCs saying across the board, this is incredibly exciting, but we're not doing deals in this space because we just don't see adaptation being ready or adoption being ready. Tell us what's your thought there. If I got your question right, Andreas, I mean, so I think if it's in terms of take up by healthcare systems of big data, data analytical and deep learning technologies, I think healthcare systems in Europe present a huge opportunity. I mean, universal healthcare systems, centralized decision making to an extent, all sounds great.

27:50And there's an opportunity for tech companies to work with them, you know, have central repositories of data and really be able to feed that into foundation models and others to improve those algorithms quickly. Sounds great in theory. but at the same time you look at in the UK at groups like the NHS, fantastic institution but has had a reputation in the past for not always being the easiest to work with with fragmented customer bases in different regions. I think the NHS has done a great job in improving that situation with things like NHSX and other initiatives and has been able to work with technology providers to really take advantage of what's available.

28:39And I was talking to an LP a couple of days ago who's internationally based and has spent some time in the UK now. And he was like lauding the NHS, how he was getting a text message about his appointment and how he went in and had a procedure that was using the latest medical devices. And so, you know, a real cheerleader. So I think these are big, slow-moving institutions within Europe, particularly on the healthcare side. But fundamentally, they offer really interesting opportunities for the developers of deep technologies because of that centralization of data. And really the opportunity to deploy at scale, I would say, as long as you can get through those front-end barriers.

29:30And for that reason, you are seeing your VCs deploying into startups that are very much at the forefront of using, as an example, LLMs in a more general practitioner type setting, meaning that's the end goal of that type of business? Or do VCs in general in this space see that type of business as there's no reason? We're not there yet. I think it's a real mixed bag. It's difficult to give a generalized answer. On the one hand, talking to one senior VC in the US, his answer was, look, the algorithms are ubiquitous. And effectively, what we will see is, you know, while we've got this current wave, what we'll see are a bunch of off the shelf, deep, you know, deep learning technologies, AI platforms.

30:27And then they will have highly, highly specialized implementations. And that's where the value equation will be will be discovered for firms that survive over the longer term. So that's at one end of the spectrum. At the other end, specialist deep tech VCs that we work with and have spoken to in Europe are, as I said, cautiously bullish on the potential in the space that those use cases are being built around individual companies that they're investing into. that those companies have, while they are experts within the individual implementation of their deep learning technology, they fundamentally, as a team and a management team, have such deep networks within the business area that they know what will work and what won't work.

31:20They have a really strong sense of what the customer will buy and how to roll out across Europe and do land and expand type strategies. So it's a mixed bag. I think no one has the crystal ball perfectly on it. I think deep learning investment has been a really interesting sector where it's differentiated in that very often, you know, the levels of capital to get a company to a meaningful stage can be significantly less versus driving growth, as we've seen over the last decade or so in areas like enterprise SaaS. So it's a different skill set, highly specialized. And I think that's my view on it.

32:02It's a kind of wait and see. We continue to listen with an open mind to what our VCs tell us. It varies a lot from sector to sector. And the story, there is no fixed playbook yet. Because just on your point of deep tech, and maybe I want to echo your shout out to IQ Capital. We love the guys as well. But deep tech has been soaring with, I think, I wrote this earlier, I think it was yesterday that I wrote, since 2018, there's been like 500 % plus increase in exits and Europe is really punching above its weights. It's really exciting. Absolutely. But I want to ask you because I love the space. I'm not a specialist.

32:40I have some exposure. I love the space. Life Sciences John speaking. I'm very much a big fan of AI as both a user and as an investor. And actually in our underlying portfolio, we have a company that is probably one of the companies that excites me the most, which is the overlap of drug discovery and AI. I think it's really cool. So I'd love to ask you about AI specifically. And the big topic for anyone who's in Europe is EU's AI Act. So I'd love to ask you, any thoughts? Do you see that impacting the crossover between life sciences and AI? Do you have anything you can share yet? Are you still kind of digesting it, as most of us are?

Read the full transcript

33:18I think we're very similar to you. we're sort of ruminating on that and digesting it but i i think you know as i said before within life sciences and health care it's a brilliant use case for deep learning technologies um the the complexity the the volumes of data you get out of a single cell in terms of molecular interactions out of cells in the body trillions of cells interacting i mean it's it's a perfect It's a perfect, perfect use case. And in terms of approaches like spatial biology and molecular biology, the omics revolution, we're seeing, I think the practical answer to what you asked is the implementations that we get really excited about are within individual companies.

34:04and even what we're seeing within pharma, where it tends not to be just a deep learning medical company. It tends to be a biotech or a medical devices company trying to solve a problem. And it's a combination of a wet lab and a dry lab within a single company where bioinformatics and deep learning technologies are being used to identify and optimize for the lead asset. and it's only when that exercise is done do the wet lab then say, okay, let's start to experiment. And so it's these very symbiotic combinations of approaches to solve a fundamental problem where we see the most practical use cases that we can see generating value in the long term rather than being a pure AI play, which certainly within life sciences has been a difficult path.

35:02And there are many stories about high-profile use cases where that has not gone as well as expected. So we get really excited about those individual biotechs where teams of data analysts and deep tech specialists working alongside biomedical researchers are producing, enhancing really the existing pipelines. So Tej, before we started recording, I promised this wouldn't take more than an hour. That is now not going to happen because we got a bit excited. Just a heads up. I tend to go on. It's not your fault. It's our fault. But I think it's the perfect moment for us to go into Prism a bit more in detail.

35:48And starting off with what's the firm's world view? Why do you exist? And I think that's a great way to start things off. So we are a specialist life sciences, healthcare investor, and done at an institutional level. And what are the reasons for that? We are fundamentally long on the technological potential within the life sciences space for all the reasons that I've talked through. So we believe that the massive demographic tailwinds in terms of, and headwinds for that matter, in terms of aging populations, in terms of rises in disease, large disease areas, both chronic and specialist, are creating a demand pool that will drive this sector to be a fundamental part of institutional portfolios as we go forward.

36:40There is absolutely tremendous government backing for a push into this area, particularly within the UK, where they see the potential of strengths of the UK in this sector and are driving both regulatory change and capital through things like the Mansion House Compact here in the UK. So all of that is great to see. And for that reason, we fundamentally feel like we are the right firm with the right thesis at the right time to really capture all of that for the next 10, 20 years. At the end of the day, we come at it not just with a sort of giddy enthusiasm, but we are a dry, boring institutional investor.

37:24And as I mentioned before, what we see within the venture asset class is really an interesting financial commercial product within life sciences and healthcare venture where those strategies on the aggregate at a fund-to-fund institutional level have the potential to produce really interesting portfolios. And frankly, we're following the work of people like the EIF and the BPC in that regard. Why life sciences healthcare focused? Why not deep tech focused? or why not IP heavy or IP focused? Because that would, as an example, could encompass then automatically climate, which is arguably also going to save a shit ton of lives.

38:08So why so narrow? At the same time, I don't think it's narrow, but it's more narrow than deep tech, right? Yeah, that's true. I mean, so two answers. I would say, firstly, I don't think it's narrow. I think it's a vast, vast area that impacts, you know everyone's lives um as does as does the broader tech uh world for sure but but life sciences and healthcare will touch each and everyone's lives at different different points in our lives and and that will only increase as a trend as i as i said so i think it's a vast area both technologically both in terms of the uh the macro view of it and the potential impact on society and then secondly why not deep tech well i think the answer is we we are hugely interested in the team um within deep deep learning technologies and we deliberately describe ourselves as a firm that is interested passionate about two key pillars one is traditional biopharma and and the second is tech bio and so deliberately within our strategy we are talking to new and existing managers that are tackling this frontier space.

39:19And that itself is such a frontier space that is incredibly appropriate to venture as an investor in innovation, that we are very excited as a team about that. So we are involved in deep learning technologies, but with that life sciences lens, where we feel we have some domain expertise and really bring something to the table. And, you know, it may be the case that we do end up working with a generalist deep tech VC. That's entirely possible and within scope for us. That was actually exactly what I wanted to ask you about because tech bio is often done by firms that also do other things. So tech bio and then 20 % that and 30 % that.

40:09But, you know, how do you deal with that as an LP in your strategy? As I said, I think we are open-minded to the strategies that are playing out. We're also a co-investor. So where we see a strategy that maybe is 60 % deep life sciences, 40 % deep tech or 50-50, and we think the fundamental commercial strategy of the fund has been working, well, A, we're interested in deploying dollars in that, but B, we know that then there's a significant probability that that firm may identify the outstanding tech bio company of the next five, six years. And so therefore it is appropriate for our portfolio.

40:52From a portfolio construction perspective, Tej, how do you think about hardware? Is that something that you want limited exposure to, you're quite bullish on? I'll give the cliche quote, hardware is hard, and no less so than in life sciences and healthcare. I think it is a tricky area, if I focus on medical devices. What we saw over the last five, six years was a number of VCs pulling back from that space, both because of the capital intensity of some of those projects, but also a very tricky regulatory environment. Europe versus the US. It is a very tricky area, but fundamentally, it also has the ability to impact patients' lives massively.

41:44And so we feel comfortable, I think, if I speak for our firm, we feel comfortable going into it with battle-hardened VCs who have it as a component of their strategy. Would we go into a 100 % medical device-focused VC? I'd never say no, but I think that is a tough play for the reasons I mentioned. Would you ever consider, and now I'm bringing it to an LP portfolio level of, you might have five bets that have 20 % allocated to hardware, whatever those numbers are, and then kind of would you ever consider like, maybe I'm a bit overexposed now from a whole portfolio perspective. Would that be something in your mind?

42:27We do think in that way. I mean, as a funder-fund investor, we fundamentally are looking for the best fund managers to work with. That naturally then starts to produce a shape of the underlying portfolio in terms of the sectors that those investors are invested in. But at the same time, we take a framework approach. And so what we do is at the outset of a fund, we map out where we think from our own technology view of the world and from our own commercial view, where we want the capital in this portfolio to end up at a high level. It doesn't mean we're going to achieve exactly that. But what we then try to do is monitor on an ongoing basis how that spread between biopharma, medical devices, diagnostics is starting to build up and how it's mapping to that original intention.

43:19And it's okay if it's not a perfect match. But we definitely do take that kind of framework strategy approach. for any GP listening in that is either doing stuff in biotech, tech bio, deep tech. Could you give us a quick rundown of what are you looking for in terms of min and max? And that goes for fun vintage, that goes for fun size, that goes for stage, that goes for just give us a rundown as complete as you can. Sure. So hopefully we don't have too many min's and max's, but we keep things pretty flexible. In terms of our portfolio construction, we have a core focus on established managers, and that means really at a fund three plus.

44:09However, we have a specific allocation for emerging managers, so around a 20 % or so allocation. It's fairly flexible. and the reason we do that is because emerging managers is a very specific skill set it's that they are not easy to deal with there's lots of basics that you have to go through and really understand have they figured that out but it is an incredibly useful way within ventures specifically to access frontier technologies and deal with small and nimble teams so we very much have that mindset mindset it's part of my dna having come having started my career in the emerging manager program of British Business Bank.

44:47Then in terms of other min's maxes, I mean, our check size range is a reasonable spread. At the top end, we might do a 10 million euro deployment. Into earlier stage managers, we might look at two and a half million at that type of level. In terms of sectoral focus of a VC that we're speaking to, I would say probably if there's a sort of 50 % life sciences, healthcare focus, that's a good rule of thumb for us as a minimum. But as I said, even then, we encounter very specific, interesting use cases where we think the potential for identifying outstanding companies, for example, in deep learning is possible and we keep that flexible.

45:36Geographically, we are broadly split between the US, Europe and and the UK. So again, we have plenty of scope there, although we look at it both at the level of the VC manager, but also how they've deployed in the past at an underlying portfolio company level. And as I said, we take a framework approach in terms of technologies. We don't have fixed percentages that we will only deploy into this much, you know, biopharma. Could you share with us what the portfolio model of someone like you looks like? How much is allocated to funds? How much to direct? How much to U.S.? How much to Europe? How much to UK?

46:22How much to early stage? How much to growth? And if you can also expand a bit when you state those percentages, also why? What's your reflection on that? and then David and I will jump in with questions along the way. So our portfolio construction is fairly straightforward. We are a pure life sciences healthcare investor at the top end. We have an 80-20 established versus emerging manager approach, as I said, broadly geographically, 50-50 US, this is the UK and Europe. check sizes ranging from two and a half to 10 million into 15 to 20 fund investments. So really a core fund-to-fund approach. Why 15 to 20?

47:09Because that's the one thing that you might be, you know, there's some decisioning there, right? For sure. I mean, so for us, it was really a long internal conversation, a fair amount of statistical work. And what we triangulated to, and also the lens of what's available in the market, how many funds do we think are in our target universe? How often are they going to be coming to market within particular vintages? And what we triangulated to was that kind of number, specifically because we felt it offered the right level of diversification within our portfolio. there's excellent work by I think it's Thomas Mayers or Mayonet the guys from the EIF who've done some research and some reading and some analysis of this point and I think that you know some of the statistical work we did pointed to that being the right level of diversification without being over diversified but also fundamentally for us within our investment period being operationally implementable with a team like ours.

48:22So putting all those factors together, we think, practically speaking, each year, we will have a universe of really interesting managers to select from where, you know, choosing five or six is and getting those deals across the line is fundamentally doable within a three-year investment period. You didn't state the size of the fund, but you did state that it is a fund. So it was incepted by a family. That family has then decided to build a fund instead of invest out of a balance sheet. Could you share with us a bit about that decision process as well and why that was perceived by the family to be the right thing?

49:06So we are backed by a German family office. They are highly entrepreneurial. They have built a number of businesses. And when they began that conversation with me, it was always one about building an institution. This was not going to be an internal family office balance sheet strategy. And that, I think, reflects their mindset as business builders. And there are simply well established structural approaches that within a GPLP structure that work well. And in terms of then have growing a series of funds under a long-term institution and growing that institution over time that's where they felt it was the maximum opportunity to exploit the space and to to to really grow prism ventures into a world-beating allocator um that is that is seen by other institutions as the specialist in the space so it was a it was an early conversation it was very clear on both sides that's what we wanted.

50:14Before we go on to our shout out section, if you could enlighten us a bit on what you look for in the managers, I think that's worthwhile diving into. Yes, and stop me if I go on because that's my day-to-day job. So look, at the high level, like most other LPs, we break it down very simply. At any VC we look at, or any opportunity. It's team, track record, investment strategy, how are they doing in their fundraising, and what are the terms on offer, which sounds simple enough. There's a lot that then gets unpacked underneath each of those categories. So on something like team, do we fundamentally like this team?

51:03Do they have a track record of really investing together that's demonstrable. If we really lift up the hood on data sheets and individual track records, who's doing the work in this team? Is it concentrated in a couple of partners? Is it actually two principals doing all the work? What really is the dynamic in this team? And we like to see a machine that works and that's being tested. Tricky in the case of an emerging manager, but whatever evidence you can gather in that regard is helpful and it's up to you whether you want to take that bet or not. But we're open to different models. We're open to very different looking teams, but we like to see a machine that works for whatever reason.

51:47We just want to understand how that is working. Has it worked in the past? Will it work in the future? Are there signs of trouble? If we do referencing in the team, in the market, one-on-one interviews, are we seeing any patterns here? Is it too dependent on one partner. So things like that are some of the elements we try to look at. Is there a succession planning approach here? What is the firm's approach to diversity, for example, in a broad interpretation of that term? Is it a sort of aggressive up or out culture? Is it a very, very level playing field where everyone's in the investment committee together?

52:29we want to understand all of that. Is it an aggressive up or out culture? What's your take on that? I've seen it work. I mean, I think that for some firms that is entirely suitable. That's part of their DNA. It's part of what has made their success. And it is absolutely compatible with an approach that focuses on bringing in the best people and progressing the best performance. That can lead to a team that is highly diverse in terms of gender, age, ethnicity, all those traditional measures. But fundamentally, when you sit down in front of them, has a team that has incredible diversity of thought.

53:19And I think that, so as I said, we are open to all models as long as it works and an up or out culture for certain firms is part of their DNA. It doesn't work for other teams who are much more, I would say, less aggressive. And where it suits their strategy are all about building a family, keeping that family together long term, keeping that intellectual knowledge. And that is absolutely the case for certain VC firms. But for firms, and very often they've tended in the past to be firms that are maybe have a little bit more investment banking, maybe a little bit more of that culture in their background, but it's perfectly valid.

54:05And if that's their way of turning capital and getting deals across the line and identifying best of breed opportunities, we're open to that. As long as there are safety limits, it shouldn't be too aggressive or or too unfairly up or out for sure. But yeah, and there are plenty of examples. I have one final topic. I love the surface, Tej, succession. And I know you have some thoughts around this because we did brainstorm a bit before the conversation. And as you have a focus on more established managers, it's even more relevant, I guess, especially when I think of some, I won't name anyone, of course, When I think of some of the funds that we know that are like on fund four, fund five, we're definitely seeing that come into play, new generations of partners and so on.

55:00So I'd love to ask you to share a bit. I'm not sure how to phrase it, but when you think of succession, what are the core things that come to mind? And any tips that you could share for, I like to call them emerging blue chip managers that are going into becoming established? Sure, of course. Well, I think the easiest way to describe it is, you know, when I come and sit in front of a VC and start to lift up the hood in terms of diligence, what looks fundamentally healthy to me as a firm. And I think that is, at the top end, really good leadership at the partner level, people who have built firms before either individual corporates or have that background of building.

55:43building and they are looking to build their firm and they have a long-term mindset that potentially goes beyond their own tenure because they're aware of the importance of not just their own individual situation but the impact that their firm is having and that they you know may have built the firm as a two-partner team they took all the risk you know they started in that room together, but they've, where appropriate, handed across the reins to others because that is operationally optimal, but also is good for the long-term health of the firm. So what we'd like to see are firms that have a good spread of responsibility at the top end, that partners work very closely with the next levels, the principals and associates and analysts, that they've all had a strong involvement in bringing in and recruiting those people.

56:45And so there's strong buy-in across the firm as to why they like that deep bench that they've created. And that they have a rational approach and that the junior bench feel that, that they fundamentally feel there is a rational approach to progression and that this isn't just a pick your favorites type situation, that it's partly based on their adoption of firm culture. It's partly based on their outstanding performance in terms of deal sourcing, deal selection, deal analysis and deal execution. And the economics, in a sense, also reflect that so that there is a good broad spread of economics across the team.

57:28The broader, the better. And the healthiest firms we have seen genuinely do that. And that's not an easy decision to make when a firm reaches a certain size, there are grumblings. It's a hard exercise for a firm to sit down and say, OK, let's take a look at ourselves and really think about the point we've got to and do this not just because there's one loud voice in the room, but do this because we as a firm want to have a healthy progression. and uh yeah i think those are fundamentally the you know some some of the things that we like to see and and the overall umbrella for that is team culture a team that are happy they get on with each other uh they love the culture they they you know they they really there aren't grumblings coming out when we do one-on-one interviews with uh with with team members there's there's a general sense of enthusiasm doesn't mean you need to fake that you know we're pretty good at picking up on that stuff, but that it's a fundamentally happy team that like each other and like working with each other and are aligned to the long-term mission of what the firm's trying to do.

58:37So Tesh, we need to get on because we have more to cover and I think we're on our 60-minute mark. Fun editing job approaches you. We're going to put everything out, Tesh. We don't cut things short here. But I want to ask you, Because in our preparation for this, you gave us a long set of questions that you look at when you're evaluating teams. Yes. First, can we put that publicly together with the episode? Why not? Go ahead. Go for it. We're very open about the questions we ask. And as I said, that is a small subset of where we go with things. but why not? Beautiful. I ask you, of course, because I think that there's not that many places where you have good repositories of LP information, right?

59:41So we always try and leverage it when we have the opportunity. So everyone listening in, if you want to hear, and this is at least 30, probably 40 questions that Tesh and his team go through when they look at GPs. So go on to eu.bc and you'll find it there. And then before we go on to the next segment, I just want to ask you, is there anything here that you feel that you would have loved that we made it just to talk about at least briefly before we go on to give you a shout out? The key thing I would pick out of that long list of questions for us as an institutional LP is very often portfolio construction.

1:00:23It's a dry topic. It involves looking at spreadsheets and working through fund models, but it is absolutely incredibly important. And it comes back time and time again that a firm might have incredibly dynamic personalities and individuals, an incredible technology thesis. But if fundamentally the basic mechanical plan for turning a certain amount of capital into a larger amount of capital doesn't work on paper, hasn't been proven out in the track record, that will come back to bite again and again and again. And when you see that fail, Tish, when you see that chain of beautiful, beautiful team all the way down to having a beautiful portfolio model break, what do you see being the cause of that?

1:01:10And is it irreparable for the VC? meaning one might think well if I'm a good cook and you've got the recipe and you think my recipe isn't good well why don't we just work on it a bit together and then then then you know we can still do this thing together well listen it is always a dynamic conversation with partners you know between us us as an LP and the firm and I hope as a value-add LP we try to keep people honest in a good partnership approached way and sort of comment where we think that there's things are going adrift. So where it goes wrong is, I think, an element of strategy drift that just happens organically.

1:01:56The market changes, perhaps firms want to go later stage. We see that a lot where a firm that started as an early stage investor has been burned on the fundamental risk that comes with early stage investing and wants to move later stage to have more certainty over the outcome of their fund and fundamentally, you know, the delivery of carry to them as a team. So that starts to occur and that might be fine and it might be appropriate to where market conditions are at, but is it their skill set? Because early stage investing is different to late stage investing. I think, you know, it is clear that growth of AUM is a thing that is front and center in a lot of managers' minds, and rightly so.

1:02:40I mean, they are looking to grow their firm. They're looking to grow themselves as a force in the market. But that, you know, growing from a 150 million fund to a 400 million fund to a, you know, 700 million fund, that is a huge and fundamental change in portfolio construction. How does that work? You know, is it going to be 15 to 20 deals in that portfolio? What is the initial check going to be? What's the stake you're going to take? Like, does the strategy scale at that kind of level? And very often the answer is no. You know, the tired cliche that venture doesn't scale does come back again and again and again.

1:03:17Unless the firm have really thought that through and have a really interesting strategy, which they've used to bridge from that initial strategy to this increase in AUM. When you're already in a fund three and they're pondering fund four and they're looking to go from 150 to 300. And they might not necessarily, but that's on their mind. How do you approach that as an LPAC member and as an LP? How do you wish that managers work with you? So as an LPAC member, I mean, I focus on the fund. I'm an LPAC member of fundamentally, and I try to stick to that discipline. But as an LP being spoken to about the next fund, I really want to understand, again, what is the portfolio construction here?

1:04:11Why do you think the strategy scales to that level? Is it just going to be a direct scale up of initial and follow on checks? Are you going to tweak the strategy because you think there's fundamentally an opportunity to take greater ownership at the initial check? Have you tweaked your follow-on strategy and the way you're doing that and how you're allocating those reserves to the best opportunities versus underperforming opportunities? So do you have a plan that fundamentally works? Also, how will this growth in AUM affect the firm? If you can do it, it can be an incredible positive for the firm.

1:04:51Greater management fee, greater flexibility to grow the team, grow the platform and become a force for good in the market. So we try to look at all those aspects, both the firm, the fund, but always our first priority as a commercial investor is, is this going to dampen down returns in what we thought was a fundamentally good strategy? Or is it in some way going to enhance it and increase their ability to win the best deals? Can I ask you, because when you're of the size that you are and you're doing the size of tickets that you are, When does a fund get too big? Because fundamentally, a 150 million euro fund will have a different ability to do 5x than a 700 or a billion or more.

1:05:34And I always say, well, when I talk to private LPs, families that want to do and reason, well, perfectly fine, go ahead and do that. But just expect that they're probably not going to do 10x on that, right? And if you're a funder fund that tries to deliver the best possible returns, there is a point where it gets tough for you with a 5 million euro ticket, as an example, to get meaningful returns out of something. Right. So, again, it comes back to us and our portfolio construction. And, you know, perhaps the smaller checks into smaller funds with higher multiple potential, but at the same time, higher risk, you know, is entirely appropriate to the construction of our institutional portfolio.

1:06:22At the same time, we do think about we want to have a core engine that works. And that core engine should be with established managers who have a track record of producing a certain level of performance reliably. We will absolutely look at, you know, are they doubling or tripling their fund size? Well, that would indicate that this is a new experiment for them. But if it's a logical growth of the fund, for example, from 300 to 500, where it's effectively expanding capital within the same existing strategy, we're open minded to that. So as with all good asset managers, we want to build a balanced portfolio that blends deliverability with us fundamentally taking venture risk, which is our strategy.

1:07:14Tej, now it's time for our shout out segment.

1:07:26I'd love to ask you to give a shout out to a co-investor angel or LP for being awesome. And of course, do share the story behind that awesomeness. I'm afraid I'm going to be a bit repetitive. I'm going to call out Ian Connors here at British Patient Capital. He was the person that recruited me there. He taught me my trade as an LP. He was a superb mentor for me personally. And I really learned a lot from him in terms of growing an investment team and how to compose an investment team in terms of the people. And the power of investing as a team where there are divergent voices. And how do you actually involve those voices on a deal where somebody completely hates it?

1:08:12bringing them onto the deal team, making sure that, you know, they have the voice that is appropriate. So lots and lots of learnings from BPC broadly, but Ian in particular, one of the best things he did with me was really kept on, I would write my initial investment papers and Ian would be like, look, that's great. And you've definitely captured the, you know, to the technical answers. But this is not the voice that I hear in our investment teams every day. You know, let's sit down together and let's put aside all the materials. Let's have a talk about this deal. And we would talk about the deal.

1:08:54He would get me saying what I really think. And he would go, that's great. That's great. That's great. That's not in the paper. And so in an appropriate way, he was great at bringing out that structured intuition and making sure that that isn't lost in a broader set of technical analysis. And so I've kept that learning. I'm using that learning and implementing it in my own team at Prism Ventures. And, you know, in a world of sort of copy and paste and rehashing and, you know, let's get the AI to write it, the power of an individual and their thinking must not be lost because it is the ultimate algorithm.

1:09:42It is the ultimate distillation of large bodies of data into an investment view. And so thanks to Ian and all his learnings.

1:09:58so now let's go to the three biggest learnings that you've had in the last 10 years of your life and we're going to make this a rapid fire just as our final closing segment because we are very close to the clock absolutely uh so uh i'll give you a few and hopefully it doesn't go beyond three but um look fundamentally the biggest learnings have been over the last five six years the accelerating breakthroughs in biomedical science and the incredible new modalities that are coming through and have the power to change all our lives in positive ways. As I mentioned, the power of teams in delivering projects and investment strategies and the factors that make an outperforming team and how to manage that team effectively.

1:10:47and uh if i throw in the last one maybe a bit more personal um really on the power of things like personally meditation sleep exercise um not only in sort of keeping yourself physically and mentally healthy but also in terms of giving your brain downtime and allowing it to to process uh complex information, which is essential in our business, you need that downtime to really let your brain stew and let the subconscious work. That is not something that comes easy to me. Put it like that, sleeping. Letting the subconscious work, I don't think we really have the willpower for that yet. Maybe a final one then.

1:11:34Cold showers, give that a try. I I picked that up a few years ago and that is very good for sleep. So now let's go into the quickfire round to wrap things up. And now, the quickfire round.

1:11:58Tej, what advice would you give your 10-year younger self? trust yourself and you know trust yourself to keep doing what you've been doing which is following your intellectual nose even though that that that produces a long and varied career um it to my younger self you know trust that it will lead somewhere exciting uh that you might not might not be obvious to you right now and um you know maybe have you heard of this lp thing um you might not be aware of it but it might be suited to you so give it a What are your top tips for emerging VCs across Europe who are now fundraising? Yeah, great question.

1:12:38I think stamina is key. Starting a new firm is incredibly difficult. It could take up to two years to see whether this thing works out or not. So stamina at the personal level, financial, in terms of the conviction around your thesis, and finally pursuing us pesky LPs is absolutely key. As we talked about before, I would, even though it's a tricky exercise and maybe somewhat theoretical, I would try to think about the 10 to 15 year plan for your firm. How are you building out towards that vision at the outset of your journey? And how are you going explain that to LPs who are looking for that multi-fund, multi-year, stable relationship.

1:13:26That's absolutely key. And maybe a final one, which is you yourselves, as VCs and emerging VCs, your job is assessing and selecting investments. So really turn that lens on yourself, which I'm amazed how often I see firms don't do. And they look to me to do that for them as the external party in the LP. But really try and sit down, have an offsite, get the whiteboard up, take an honest look at yourself as a team and a strategy and firm and ask yourself, does it stack up? Would you invest in your next fund? And what is the most counterintuitive thing you've learned since you've been in venture?

1:14:07Well, we touched on it earlier that biotech is supposedly this binary asset class. I don't think that's entirely true and that it is this incredibly consistent and performing sub-asset class within venture. It isn't something that I had known when I first came to the space as an LP. So definitely was counterintuitive for me initially, but no longer. I had thought coming from a background in private equity, you would always want to go into the big firms, get that reliable machine, take advantage of their access to deal flow. But the outsized role of emerging managers within VC is key and can never be forgotten.

1:14:51And I think should play an important role in LP portfolios that are looking at venture.

1:15:01So on that friendly note, let's close off this conversation and say thanks a million for everyone tuning in. Thanks a million for joining us, Tesh. We hope you enjoyed the episode and do drop us a review, follow the pod and subscribe at EU.BC where you'll also find the diligence list or at least small parts of it that we teased just earlier in this episode. Thank you. Thanks, guys.

1:15:55Adjust them to each sideopian white Money

From the publisher
Today, we are joined by Tej Panesar. Tej is a Partner at Prism Ventures, the UK-based institutional investor focused on the life sciences and healthcare sectors.

Prism invests in the best-of-breed funds managed in the US, UK, and Europe through fund of funds and co-investment programs. He previously worked as an Investment Director at British Patient Capital, a UK government-backed institution very similar to the EIF and one of the largest investors in UK venture capital.

With +425M pounds invested in the UK and Europe, Tej led investments into famed firms like IQ Capital and SV Health. Tej and his team have a wide lens across the life sciences and healthcare industries but a strong focus on traditional biopharma and areas like tech bio.

Go to eu.vc for our core learnings and the full video interview 馃憖

Chapters:
00:00:00 - Introduction about Prism Ventures
00:03:55 - From Crowdfund Platforms to Venture Capital
00:11:09 - LP Perspective on High-Tech Work
00:14:50 - The Non-Binary Nature of the Life Sciences Sector
00:18:34 - The Exciting Opportunities in Biotechnology and Healthcare
00:26:28 - Adoption Challenges in the Health Sector
00:30:23 - The Value Equation of Learning Technologies
00:34:01 - Symbiotic Approaches in Life Sciences
00:37:50 - Focus on Life Science and Healthcare
00:41:36 - Investing in Europe vs the US
00:45:18 - Portfolio Construction and Diversification
00:49:18 - Building a Long-Term Institution
00:53:04 - Diversity and Culture in VC Firms
00:56:50 - Evaluating Team Culture and Portfolio Construction
01:00:29 - The Importance of a Viable Business Plan
01:04:04 - Scaling the Fund Size
01:07:48 - Investing as a Team

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