Season 2 Official Trailer: Lifespan with Dr. David Sinclair

18 May 2026 · 2 min

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In short

Season 2 trailer for Lifespan, centered on the idea that “biological age” predicts lifespan and healthspan, and that aging can be slowed or reversed by targeting underlying mechanisms rather than counting years.

Guest backgrounds

Dr. David Sinclair, a scientist and professor who has studied slowing and reversing aging for over 25 years.

Key claims

Aging is the top risk factor for cancer, heart disease, and dementia; aging is “software corruption” that can be “reinstalled”; it’s not too late to start improving future health now; longevity gains are achievable for individuals and families; interventions can be tested without guessing.

Notable examples

Other species that live longer than humans as models for learning how to extend healthy life.

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Transcript

Automatic transcript. May contain errors.

0:00Dr. David Sinclair:Your biological age doesn't depend on how many times the earth has gone around the sun. Biological age predicts not just how long you might live, but also what kind of a life you're going to live. I'm David Sinclair, a scientist and professor who's been studying how to slow and reverse aging for over 25 years. Aging is the number one risk factor for cancer, heart disease, and dementia. We view aging as the corruption of software, and my lab has found that you can reinstall it. It's important for everyone to start working on their future health and longevity now. It's not too late for anyone. You want to stay young, you want to stay healthy and you certainly want to stay alive.

0:41Dr. David Sinclair:There are many species that live longer than us and we can learn from them. We can dramatically improve human health by targeting aging itself and it's something that's quite achievable for you and your family. At Lifespan we want to give everyone 10, 20 more years of healthy life. We are in a new era. The technology is coming. We now live in a world where we don't have to guess whether interventions are working. Lifespan's mission is to help you and your loved ones live your longest, healthiest lives. You'll get information that is not only factual, but also found nowhere else. So come join us at lifespan.com, where we're building the world's largest longevity community.

1:24Dr. David Sinclair:We'll learn together and support medical research together.

From the publisher

What if aging is more reversible than we once thought?

Season 2 of Lifespan with Dr. David Sinclair, A.O., Ph.D., explores the latest breakthroughs in longevity science - from epigenetic restoration to fasting, exercise, sleep, metabolism, and the emerging technologies that could help us live longer and healthier lives.

Drawing on more than 30 years of research and conversations at the frontier of science and medicine, Dr. Sinclair breaks down complex discoveries into practical, evidence-based insights designed to help you understand how the body ages - and what may be possible to slow, optimize, or even reverse aspects of that process.

This season features:
• New episodes on fasting, exercise, metabolic health, and longevity science
• The latest research on biological aging and cellular repair
• Practical tools for healthier living backed by scientific evidence
• New conversations around the future of medicine and human healthspan

We're building the world's largest longevity community, focused on supporting medical research and living longer, together. Join us at https://lifespan.com

Follow Lifespan:
Instagram: https://instagram.com/lifespan
X: https://x.com/JoinLifespan

Follow Dr. David Sinclair:
Instagram: https://instagram.com/davidsinclairphd
Threads: https://threads.net/@davidsinclairphd
X: https://x.com/davidasinclair
Bluesky: https://bsky.app/profile/davidsinclairphd.bsky.social
LinkedIn: https://linkedin.com/in/davidsinclairphd
YouTube: https://www.youtube.com/@LifespanOfficial

Watch or listen on YouTube, Spotify, and Apple Podcasts.

More from Lifespan with Dr. David Sinclair

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Season 2 Official Trailer: Lifespan with Dr. David SinclairLifespan with Dr. David Sinclair · 2 min
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