The Creatine & Strength Mashup Every Woman Needs

18 Aug 2025 · 50 min · 16 chapters

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In short

How strength training and creatine work together for lifelong health in women—muscle/strength “span,” sarcopenia prevention, and creatine’s benefits beyond the gym (energy, mood, cognition, bone support).

Guests

Dr. Gabrielle Lyon (strength/aging focus; “muscle mommy” framing; emphasizes earlier resistance training and creatine for women, including plant-based and low-creatine diets; discusses creatine types/dosing and safety). Dr. Andy Galpin (exercise physiology; explains strength vs hypertrophy, power, and leg/grip strength links to mobility, social engagement, cognition, and dementia risk). JJ Virgin (women’s real-world supplement/training perspective; shares creatine use during keto and pregnancy planning; addresses concerns like water retention and dosing approaches).

Key claims

Women often have lower creatine stores; creatine is highly studied and generally safe; it won’t “make you bulky,” though temporary water in muscles may occur. Examples: squat progressions (air squat to chair to added weight), deadlift alternatives (water bottles), vertical jump pencil test, and hip-fracture/strength decline statistics; menopausal women studies on bone mineral density and mood/cognition.

Written by AI. May contain mistakes. Listen to the episode to check what was said.

Chapters

Tap a time to open that second in VO

The Importance of Creatine for Women

0:45 to 3:38

Discussion on creatine's benefits for women, especially in relation to muscle health and menopause.

“Can you give us the tea on creatine for women?”

Optimal Strength Training for Lifelong Health

3:38 to 11:07

Exploration of why strength training is crucial for health and how to start effectively.

“And I don't know about you, but when I started taking creatine, like, where has this been in my life?”

Optimal Strength Training for Lifelong Health

11:18 to 12:47

Exploration of why strength training is crucial for health and how to start effectively.

Building Strength and Healthy Habits

13:20 to 14:01

Advice on focusing on strength and healthy habits over weight loss.

“That's kind of the sweet spot more is better, but you know, that's the, you got to hit that.”

The Importance of Strength Training

14:01 to 23:07

Learn how strength training can improve quality of life and longevity.

“around and I'll do some treadmill walking with my wrecking vest.”

The Importance of Strength Training

23:08 to 24:42

Learn how strength training can improve quality of life and longevity.

“easier, you will want to hear this from AquaTrue.”

The Importance of Strength Training

24:58 to 26:29

Learn how strength training can improve quality of life and longevity.

“pregnancy i find it to be so relaxing and beneficial for my skin and i personally love the brand Boncharge.”

Understanding Strength Span

27:10 to 28:00

Explore the concept of strength span and its impact on wellness.

“Because as soon as you start losing strength at age, then nothing else will function.”

The Importance of Leg Strength and Mobility

28:00 to 30:00

Discover how leg strength impacts mobility, social activities, and mental health as we age.

“That said, if we were to go outside right now and walk from the bottom of the stairs all the way up here, right?”

Cognitive Function and Strength Training

30:00 to 31:50

Explore the connection between physical strength and cognitive function in aging individuals.

“And we have both correlation and causal data behind that.”
Show all 16 chapters

Creatine: Myths and Benefits for Women

31:50 to 34:10

Learn about the misconceptions surrounding creatine and its surprising benefits for women.

“Still to this day, if I said high intensity, for years, that's always going to go in that same bucket.”

Supplementation for Women: Insights and Recommendations

34:10 to 38:02

Get insights into effective supplements for women, including protein and omega-3 fatty acids.

“And now you're either going to add some potential bone mineral density, or you're going to maybe at least negate it from losing and from going away.”

Supplementation for Women: Insights and Recommendations

38:10 to 39:15

Get insights into effective supplements for women, including protein and omega-3 fatty acids.

“And I have to tell you, investing in clean air is one of the most important ways to invest in your health.”

Creatine's Role in Women's Health

39:30 to 42:00

Discuss the potential benefits of creatine for women's health, especially regarding mood and muscle retention.

“i'm so glad you came out with a creatine do you know the data is unbelievable yeah creatine is It's one of the safest supplements.”

The Benefits of Creatine for Women

42:00 to 44:18

Discover how creatine can enhance mood, memory, and muscle retention for women.

“I realize that I'm not giving you the mechanism, right?”

Optimizing Health through Muscle

44:18 to 46:45

Learn about the significance of muscle mass for longevity and overall health.

“Which is the recipe for a great supplement.”
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Transcript

Automatic transcript. May contain errors.

0:00This is the Pursuit of Wellness podcast and I'm your host Mari Llewellyn.

0:07Hey everyone, welcome back to the podcast. Today's episode is a powerhouse mashup all about two major players in the world of fitness and wellness, strength training and creatine. Whether you're just getting started or you've been lifting for years, we're diving into how these two go hand in hand and why they matter at every stage of life. We've got some expert voices joining us including Dr. Gabrielle Lyon, Dr. Andy Galpin, and JJ Virgin with a real world look on how strength routines and creatine use evolve over time from building lean muscle and boosting energy to supporting mood, mobility, and overall resilience.

0:41We'll explore why strength training is one of the most effective tools for lifelong health. And if you've ever wondered what creatine actually does, or if it's just really for bodybuilders, we're here to break down the science, bust the myths, and show you how it can support you in more than just your gym goals. Can you give us the tea on creatine for women? I love creatine. Okay, you love creatine. I love creatine. I would definitely, I wish I'd started this much sooner. I can't believe I didn't. I think it's because when I was training people at Gold's Gym in Venice, it was such a bro dude thing.

1:15I was like, none of that, you know, and I just never looked at it. And then as I started to really look at sarcopenia, there were a couple of things that became very clear. Number one, like, why are we not all taking creatine, especially women who have less tissue sores, as we know? And, you know, especially if you're a plant based woman and you're not getting enough, you're not going to get it from your diet, you're only going to make about a gram. But you look at what it does. Great study in menopausal women helping with depression. So we know it helps with cognition, it helps with bones, it helps with skin, it helps you work out harder.

1:50And I have been amazed because as I've been talking about creatine, I have gotten so much resistance that I'm blown away. Like you might as well just say, take this and you're going to blow up. They're like, but what about my hair, my kidneys, and I'm going to retain water and blah, blah, blah, blah, blah. Oh my gosh. Like this one, I have gotten more feedback on this supplement than anything else ever. I think it's, is it the water retention weight gain concern is the big one for women? It is. And I am really, so I'm digging into creatine right now, big time. I have been using creatine monohydrate because that was, you know, the oldest, most researched one.

2:34I met the guy who has creatine HCL, who created it. He found me because I was speaking at a medical conference and he tracked me down on LinkedIn and gave me the whole spiel on creatine HCL. And I'm like, okay, well, but you created a creatine HCL. So he goes, this is like the iPhone 15 and that over there is a rotary phone. So I'm really looking right now to see what makes the most sense, which type of creatine, whether it's the most pure form that's 99.9 % pure or the regular form that's 99 % pure. Like how much does this matter? Or is it the HCL that turns out you can use a lot less of and may not cause some of that fluid retention.

3:13So what is the fluid retention? And I'll tell you what I've done to work through this and help people. Some of that fluid retention is amazing. It's in the muscle, right? Which goes back to, you've got to use a biomedic scale because then you'll go, oh, this is awesome. I have more water in my muscles. This is what I want. Right. This is the best thing ever. I did not take creatine and put on body fat. And I don't know about you, but when I started taking creatine, like, where has this been in my life? I can now work out harder. It's fantastic. And you didn't see bloating when you first started taking.

3:50No. And I even did loading. Like I did loading. I did five grams, four times a day because what you have to do is get your creatine stores up okay and but i have now a different way i would teach people to do it based on all the feedback i'm getting from people i just went and was like fine i'll do five days and load it a little a little tummy thing one day i was like nothing really um and i've been taking five grams at least a day ever since but now i'm kind of playing around with the HCL. Now, what I would do with someone is I would start them with a gram. Okay. And then I would take them to two, then to three, depending on their size, I put them and their diet.

4:37If you've got someone who's totally plant based, let's go to five. But depending on your size, somewhere between three to five grams. And then you just always stay there. Now, there might be an advantage to doing that before you go to the gym seems like it at first I was like it doesn't matter because it's tissue stores but it seems like it could be helpful and I always figure I'm gonna get every advantage I can why not why wouldn't I so um that's how I do it as I take it in the morning do my electrolytes mix it all in like a habit yeah I'm just starting to use creatine again I used it so I was keto for a while oh you were how did you like that so I think it's a great tool.

5:16Right. I answer tools. Yeah. I think it's a great tool. I did it probably for a little bit too long. How long did you do it? Like on and off for three years, to be honest. Um, it wasn't just for weight loss. I also did it for my skin and I felt like it was incredibly beneficial for my skin. Um, but I also found when I did stool tests that I was missing some crucial bacteria. So now I'm eating sweet potato again. I don't respond very well to carbs. I don't feel amazing afterwards. Like potatoes are kind of like my sweet spot. I don't feel great with rice. Like I've had to kind of experiment and figure out the best thing for me.

5:57But I liked it. And I used creatine during that time to kind of like help with the muscle. You know, I felt like I wasn't getting that pump at the gym. And I remember Greg recommending creatine and now I'm starting to use it again And after having so many people on the show, tell me how amazing it is. Yeah, well, especially aren't you trying to get pregnant? Yes, ma 'am. Yes, yes. It helps with that? It's not helping with that. But when I look at pregnancy, I look at a couple different phases. There's before you even think about getting pregnant, where you're doing all of the detoxification and upgrade to make sure that your body's super healthy and, you know, saunas, all that.

6:33Then everything that you want to really maintain is great. nutrients during pregnancy. You start before you get pregnant, then you keep that through, then post with the nursing and the recovery, right? So creatine is a helpful supplement. Creatine is a helpful incarnate. I know you have a focus on aging optimally and focusing on muscle as we age. A majority of my listeners are probably 25 to 30, kind of my age range. Why is it important that we start thinking about that now at this age? Well, let's reframe it to aging powerfully. Aging powerfully. Aging powerfully. And this is the right age to start.

7:10You know, I feel very fortunate I was lifting weights at 16 with the high school football team with the bros. And I grew up, I mean, I went to Richmond, California. I went to a very like rough neighborhood high school and lifted weights with the football team. If in the perfect world we would be doing DEXA scans on girls in their teens and really really seeing where they were in terms of bone density and muscle. And we would start just like in the perfect world, if you had it to do over again, you would start like investing from the time you were born. Your parents would teach how to do it and you would just invest all the way along.

7:45You'd be a gazillionaire. It's the same with muscle. The earlier you start, the better. But the cool thing is you would never tell a 60 year old, well, you didn't start investing, you know, guess you're screwed for retirement. You would say start now. And that's what I'd say here start now but gosh and at this time period i can't think of a better time to really get this dialed in and started than right now because the dividends you're going to get later on in life are crazy amazing like there's all these horrible stats about aging and i can tell you they don't need to be at all if you've got a solid foundation and you just don't stop and so it's never too late to start weightlifting in your opinion no if you're 26 you're fine like i would love if my parents parents were to weightlift, but I don't even know where to begin convincing them because they just didn't grow up in that culture.

8:37Do you have any tips on like how we can encourage our parents to weightlift? Yes, they did grow up in the time of calisthenics and Jack LaLanne. And in the reality, when you look at what a lot of what he was doing, it was bodyweight calisthenics. It still was resistance training with some power training, right? Jumping jacks and things like that. So they grew up with that where I like to to do this I have a very specific progression because my favorite audience is the audience that's new to resistance training like I love that audience like it's easy to indoctrinate the indoctrinated but someone who's never done it first of all the results they're going to get are so much more you take someone who's always resistance trained you know it's like cleaning a clean window like oh I got rid of the spec you take someone who has never resistance training.

9:25It's like you've got a dirty window and all of a sudden you can see the light. It's crazy what they feel. Newbie gains. Yes. So newbie gains. But the cool thing is, and I always like to say, you don't train to get better at training. You train to get better at life. The great thing is, is you'll see it in every aspect of your life. Like everything. thing.

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12:55the way you feel when you learn how to lift weights and eat well and get strong it's like you couldn't you wouldn't trade it for anything yeah i'm excited to talk to you about that because i think the important thing there is you're not focusing on losing weight you're focusing on getting strong getting healthy and falling in love with those activities and if you live like a healthy lean person guess what will happen and then you stay there which is the hardest part of all. I first track activity and then I get them up to eight to 12 ,000 steps a day. That's kind of the sweet spot more is better, but you know, that's the, you got to hit that.

13:29Then I add some intensity a couple of days a week into that. So maybe put a rucking vest on. I think that my husband loves those. Do you do it? You ruck? I do. Uphill? No, no. Well, I live in Florida. It's a little flat. Yeah. Unless I can find a bridge, I'm out of luck. The way I see a rucking vest, it's a great way to add intensity. It's a great way to put, you know, to strengthen your bones. And if someone's losing weight, and they're concerned about a little metabolic downshift, which some of that we can offset with resistance training and adding more muscle. But the other way we could is like, wear your wrecking vest around, make it home, I'll wear my wrecking vest around and I'll do some treadmill walking with my wrecking vest.

14:08That's how I use it as just more of my sustained activity. Although sometimes at night, we'll go out and crank it. Yeah, with the reckon best. So that's the next step. Then I add in resistance training, but really focusing on compound moves that mimic what we want to be better at in life. Like if I had to pick one, it would obviously be a squat. Yep. And you hear from people, they're like, oh, I can't do that because I have bad knees, bad back, bad, bad, bad, bad, bad, bad. It's, I often think the, the reason why you say you can't is the reason why you must. What types of exercises would this be?

14:43And again, when you're first getting someone moving, a lot of it is how the nerves, you're training your nervous system. Like so often when you first start the first month, you're not going to see any real muscle hypertrophy because you're getting more of neurological learning. So can you explain what that means? Hypertrophy. So hypertrophy is your muscles getting bigger, which we know starting at around age 30, your muscle size starts to go down. It's anywhere from three to 8 % a decade. Doesn't have to. The scary part actually isn't that the muscle size is going down. It's the muscle quality problem.

15:17A lot of it is our muscles getting infiltrated with fat. Think ribeye versus filet, right? And we're losing strength. Two to 4 % of strength versus 1 % muscle. But we're losing even more power. Strength is how much could you pick up one time? Power is how fast could you do it? And when you think about what translates to everyday life and why you see people breaking a hip and never recovering is they can't catch themselves right yep they can't dart out of the way fast isn't that one of the leading reasons that older people end up in the hospital and die young i don't know how many of them how many people break a hip i can't remember that stat i do know this stat if you do if you are one of those people um and right now like sarcopenia it's something like four to 11 % of 50 to six year olds have low muscle relative to their weight sarcopenia.

16:11And then it of course just gets worse, but it doesn't have to again, doesn't. But if you are one of those people who breaks your hip at 65, it's, it's a third of those people die within a year, like never get out of the hospital die within a year. And half of the people there, they're never where they were. Yeah, you know, they lose muscle, they can never get back that's why it's so important not to get injured as you age you would start with things like doing an air squat i mean i literally i'm doing this with someone right now who is morbidly obese and we've gotten him to see back to the person he used to be which was a you know professional tennis player right and so the first thing that we did was squats but they weren't even squats over a chair because he couldn't go down that far easily like he has to pull himself out of a chair there was a squat over just the side of the chair you know an air squat next we'll go down to the chair right and then we might add a little a little handheld weight yeah but you just the form is always the limiter and then when you think about it like how many things in life involve you getting up off of something a toilet a chair a car so i would start with a squat with no body weight then you can add a little dumbbell that you hold then you You can also, once you get that foundation, you can do a squat with a jump to add some power in.

17:32Yep. One of the ways we can test a vertical jump is just take a pen, a pencil with and mark it and then jump as high as you can and mark it again. And you can get the norms for that. So that would be one. One's obviously a deadlift. And the caveat is I hear from people, well, I can't do these things because. and again if you have bad knees when i blew my knee out at 17 and then did the dumb thing again they're like you need a knee replacement i go all right i'll come back and i came back 30 years later and literally they were like i we don't know how you're walking you are bone on bone like how are you doing this but i'd strengthened everything else so much yeah that i was able to do it and then i trained for the knee surgery so literally i never used a walker i never used anything three weeks later I was on stage and so you know it's like you have to think of these things differently right so if they started with a squat they started with a deadlift what's the deadlift it might be just them doing the movement and then maybe they're picking up water bottles yeah right um them doing push-ups like in the perfect world you would go in for a physical you would get a dexa with a vo2 max you'd have to do push-ups and you would have to do like a jump test.

18:50It would be amazing. And then you'd have to do a balance test. So are you generally recommending people strength train? Of course. Have you heard of muscle mommies? Oh my gosh. I have not. This is like a, this is something I love doing when men come on the show. I have to bring up all the phrases. I'm loving, I'm learning so much from you. Yeah. You could like name programs like the muscle mommy program. Like Dr. Gabrielle Lyon is a muscle mommy. You know, That's a perfect example. Okay. She's definitely both of those things. Yep. Yep. Very much a mommy and very much a muscle. But it could also apply to someone who doesn't have kids.

19:25They're just like super muscular. I think the confusion for a lot of girls is the amount of weight that's needed. Because I think with Pilates, they feel this. I don't know if you've ever done it, but you feel this like crazy isolated pain in one area. So they're like, oh, it's, this is growing my muscle. in the early 90s, mid 90s, all the way up through like the early 2000s, we still very much dealt with strength training. These anaerobic things were a male, right? No matter how much we fought that battle, there was a couple of problems there. Number one, there was not a lot, female sports were still not accessible media wise, right?

20:05It wasn't actually until recently where female sports had really any TV time coverage, stuff like that. But even if you go back to history, women didn't even start running the marathon, start doing other activities like this until decades after men did, right? And then the participation numbers were tiny. This was growing scientifically, but you had a whole generation of females from that 1990s who were like, well, I'm kind of getting into strength training. I'm kind of getting into these things. I'm getting into sports. But there wasn't social media. There wasn't media out there. well these people turn into mds and strength coaches and scientists and now they're 30 and 35 and 40 and 45 and they're the gabrielle lions right and now these because but these are girls that got inspired in the 80s and 90s to do these things it's now coming to the forefront which is great because we've been arguing this and when you asked that question earlier about toning i'm like oh my god like for 25 years we've been fighting fighting the toning war sure and it never worked because it was dudes like me telling girls like you that don't worry you're not going to get bulky yeah which is not effective at all we needed in like honestly those female scientists and stuff to start coming forward and being the face of those movements that's largely happened and so the the muscle mommies is probably a reflection of the last you know five to seven years of folks like that and abby smith ryan and all these other folks coming from these different communities and saying i've been lifting my whole life look at me and like oh shit yeah huh you don't look like what I thought I was going to look like.

21:35If you do want to look big and jacked and bulk, I don't care as a female. Like again, you define what is good or bad. Like I don't care at all. And I don't think Gabrielle would care at all what people say, right? So you tell me what you do and don't want to look like. And we can program to that. It just had, it took a while for us to come from the female voice. You throw on top of that, such mounting colossal amounts of peer reviewed high quality scientific evidence for things that touch female pain points. And then you started getting belief in buy-in. And so I think we're probably right at the beginning of that climb because yeah, you will definitely see more there.

22:11And men have been saying this for a very long time, but some men don't like muscular women. A lot of men do. So you, I think this is certainly how I'll raise my daughter and how my wife is and how she'll raise her. It's like, you look however the fuck you want there will be some man who cares about you if you care about that but you don't have to worry about playing sports because you're too worried that like boys won't like you yeah um that will happen of course but i mean you sure hope like every amount of education we can instill in them it's like that should never be a reality that you have to deal with if you want to be strong and get all the health benefits of that we can do that in a way that doesn't make you look how you don't want if you care or even better yet hopefully you don't even care.

22:53Hopefully you just look how you ever want to look. That makes you happy and healthy. And we can hopefully by the time my daughter is at that age, that these things don't matter as much.

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27:10That's A-L-T-R-A running.com.

27:18what are some of the other benefits of having muscle mass or strength for women going at the longest end of the spectrum everyone wants to live a long healthy life of course people are aware generally of lifespan and wellness span at this point right but then there's a new a new awesome term that we call strength span and so what this effectively says is your your wellness span is going to be dictated in large part by your strength span. Because as soon as you start losing strength at age, then nothing else will function. Really easy example here. Most people are familiar by now with the importance of things like VO2 max, cardiovascular fitness as you age.

27:56This is the entire crux of the wellness span versus lifespan argument. That said, if we were to go outside right now and walk from the bottom of the stairs all the way up here, right? And I cut your leg strength down by 80%, you wouldn't make it up here. Your cardiovascular system would be going nuts. You would be at max heart rate and it would have nothing to do with your VO2 max. It's the fact that your legs are super weak. Your legs and your hands are the things that make you move throughout the world. And so that I call them, they are your interface with the world. So we know that if you have a strong interface, you're more likely to do any activity that you choose to see fit.

28:33More importantly, probably, is you won't opt out of them. Easy examples like, oh, I'm not going to take that trip. I'm not going to go to the grandkids. I'm not going to do whatever else as I'm aging. Why? Because I know I have to carry my luggage throughout the airport. It's going to be a huge pain in the butt. I'm not strong enough to put it in the overhead bin. All the steps. I don't want to do that activity. Why? There's research now that'll suggest one of the biggest driving factors of social withdrawal as you age is sense of burden. When people feel like they're a burden, they don't want to do anything.

29:06Because you've been this healthy, functioning, autonomous being for six decades, seven decades, eight decades. And now everyone is honking at you. You know, you're holding up the whole line. The entire thing's going to wait and you feel really bad about that. And so, you know, you can't do anything about that. And so you're like, I'm just not going to take that trip. I'm not going to go to that outing or whatever that thing is. That becomes a problem. It becomes a problem because it, as I mentioned, leads directly to social isolation, which is a massive driver of long-term joy, connection, purpose.

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29:38So all the physical attributes, sure, we can directly tie those to mortality. We can also draw joy and sense of connection and purpose. When you lose a sense of purpose, and in fact, you have a sense of burden, mortality is right off the reservation. We've actually seen, we actually published a paper last year, and we found that specifically leg strength predicted 5 % of cognitive function through aging. And we have both correlation and causal data behind that. And so it's examples of movement. It's examples of physical activity. You're not strong. You're not going to be physically active. Sense of purpose.

30:17So it ties into everything all the way up to directly brain functional purposes. There's excellent research on strength training and white matter atrophy in your brain. So your physical brain, not your mental health, your actual physical brain is going to stay around much longer when you strength train. And again, there are direct causal links at this point. We can make the same argument for grip strength. In fact, one paper found, I know that this is a very large study. They looked at grip strength and low grip strength predicted 30 % of dementia and Alzheimer's. And so you pick the poison you want to go after brain health mental health physical you're going to find just again mountains of evidence to suggest strength training the act of it itself as well as just being strong is going to be holding toe to how long and how well you live so you just can't make an argument that you can get away with being weak and living a long time how about supplementing for women who are weightlifting?

31:18Because I do think there's a lot of fear around, let's say creatine or some of the more performance supplements. I think maybe the problem is differentiating these things, these items, these approaches as performance-based. This is generally caused the issue when, I used to do this a long time ago, but if I said things like strength and I said, is that performance or is that health? 10 years ago in my class, everyone would have said, that's strength is performance, right? It's different now. Now when I throw that same slide up, the kids already know that's a bull thing, right? If I said anaerobic, same thing, right?

31:57Still to this day, if I said high intensity, for years, that's always going to go in that same bucket. If you talk about exercise program, if you talk about supplementation, it's the same connotation, right? So if you say creating for years, early 90s, mid 90s, late 90s, this is a performance-based thing. But now you have so much evidence on the other side of the equation. Most up-and-coming students now are being like, oh, this is a health thing, right? So you're talking about research on creatine specifically. Sure, muscle growth, muscle strength, there's 30 years of research on that. That's very well established.

32:35It's been tested in every population you can imagine. young, old, male, female, um, disease populations on disease, special populations, all kinds of things like that, different dosages. And you're seeing very high safety profiles and very high effectiveness, right? So the small issues you see with preteens, some people get kind of like nauseous or something like that from a little bit, but it's pretty uncommon. Then you have like random anecdotal reports of weird things, but like that happens with physiology, but on aggregate, it's an incredibly safe supplement to take. Benefits are in muscle and performance, sure.

33:11There's a little bit of research actually. Darren Kandow did a two-year study on postmenopausal women using this typical dosage for creatine that people say is like five grams per day. He did 20 grams per day in postmenopausal women. And they found some mild benefits in bone mineral density. So not all the areas that they scanned improved. Some of them did. I think like hips an area-ish did, but legs didn't, or some variation. So some plausible benefit. It also highlights the fact postmenopausal women took 4x the normal dosages for two years and had no issues, right? No adverse events, basically, no kidney problems, no issues.

33:56And so you're like, okay, maybe some mild benefits of bone mineral health, which is really hard to deal with, especially post-menopause, a huge deal for women. We didn't even bring that up as a benefit of strength training, right? And now you're either going to add some potential bone mineral density, or you're going to maybe at least negate it from losing and from going away. And then there's research on things like mood, brain health. There's some research, recent stuff on cognitive function, on long-term brain development, mental health. It's a little bit of an anti. So you have so many benefits in so many areas with a high safety profile that's been tested in multiple populations and countless labs for decades that it starts to become a really hard argument that that's a performance.

34:44It's just a life supplement. It's a really high, and especially when you think about what it actually directly does. Past that, you can get into any supplement you want and like on the surface, you might have this mythology that it is a performance supplement. But in reality, it is the biggest bang for your bucks are going to be the things that remove the most amount of performance anchors. So what is needed specifically based on your physiology? What are the limitations in your diet? Okay, can we then solve maybe some holes there with supplementation? Getting any supplement from whole food first is always a landslide of a win.

35:21but if you have to use them we'd recommend either sticking to the basics like that and i could certainly add more to that list or if you're going to add more make sure that they are very specific to your physiology very specific to your blood work very specific to to some limitation you're having based on a choice you've made with your exercise or something else because outside of that then you start you can potentially run into issues but but the the kind of high profile high safety high benefit ones are there so performance versus health like it's not really that different to be honest i think uh women think creatine's gonna bloat them it can a little bit um i'd say that temporarily give any person any supplement yeah some people will come back and say this hurt my stomach yeah that mean you could give them a placebo and some of that would happen so um is it possible that some women might feel like watery or bloated from creatine yeah but also like again we could give you any food and and that could happen so if you're saying like on aggregate is it a moderate risk no no and do you see that reported a lot in literature no have i given like hundreds of create hundreds of women creatine yeah have we had a huge problem with it not at all have we ever had some women come back and sure we've had some men come back and say that too we've given people chicken and they've come back and said it may blow like so it it's not any different than like almost any other substance so i'm saying that because i'm very sensitive when somebody comes to me and says i started doing a b and c and then this happened my general default is i believe them i'm not like oh yeah whatever it's like keep taking it and it's like oh my stomach is cramping like nah like weird stuff happens yeah it's pretty rare for us to hear that

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39:34i'm so glad you came out with a creatine do you know the data is unbelievable yeah creatine is It's one of the safest supplements. But not only that, for women, there might be additional benefits for women. Women have what seems to be lower creatine stores and not just based on size. Which is crazy because I think the way people think about creatine is that it's for men. So why is it so beneficial for women? I think, well, first of all, let me give you my top supplements that I would say, okay, this is what I think would be valuable for anybody, for women, a protein powder. I am obviously partial to whey protein, a omega-3 fatty acid, some kind of polyphenol that, you know, for example, a red, green, purple, or something like urolithin A, which is a prebiotic, creatine at a higher dose than you would think.

40:33Creatine at a dose between three and five is what people think of for women. But creatine, what we are starting to see, what some of the research is coming out and also Dr. Abby Ryan Smith, that women, depending on their phase of their menstrual cycle, seem to have greater benefit from creatine than other times, which again, I think that you should take creatine every day. I think that it's very unrealistic to dose creatine based on your cycle, whether you're in the luteal phase or even in pregnancy. So it's safe during pregnancy. You did not hear that from me. Talk to your own doctor, but yes.

41:14And you have to understand creatine is made in the body. We get it from sources like red meat, which we are never going to be able to consume enough that is going to be meaningful. For example, one pound of red meat might have half a gram of creatine. And if you need a minimum of three grams, three to five grams from muscle, 10 for brain health, one in eight women will struggle with some kind of mental health issue, whether it's depression, anxiety. And part of the reason, at least I'm beginning to see evidence that part of the reason is this ability to generate energy in the brain. And these are very broad strokes.

42:01I realize that I'm not giving you the mechanism, right? So I do think that the brain is very complicated. But if we know that women seem to have lower levels of creatine in the brain and that they are very responsive to creatine and it improves mood and memory, that's extraordinary. Yeah, that's amazing. So also if someone were to take it with, say, an SSRI or something that they are doing already for their mood and brain function, might begin to see synergistic effects. So it's helping muscle retention. Yeah. Doesn't it hydrate muscles too? It helps with glycogen storage. If say an individual was struggling with performance, there seems to be some evidence that it actually helps with storing those carbohydrates in skeletal muscle.

42:49Amazing. It is not going to make you big and bulky. Okay. That's the big thing is girls think it will make them bloated. That's like the number one misconception I see. I actually have been taking creatine since the beginning of my fitness journey. And I remember being really nervous i was like oh my god i'm gonna look bloated and watery but it's the best thing ever and i think that we're gonna start to see more women taking creatine yeah i hope so i believe that it is probably going to be proven to be one of the most useful supplements for midlife and when i say midlife i am talking about so midlife i guess would be what 40 individuals should start before then.

43:32So thinking about, I mean, from a health muscle span perspective, I would say as early as they're willing to. Yeah. I mean, when I was 18, I was taking supplements. I don't know if you were taking supplements. I wasn't. I wish I was. I wasn't into fitness when I was 18. It took me until I was 23, 24 to have a mental breakdown and get into fitness. But think if you had just and take creatine. Kidding aside, I definitely believe women of childbearing age in their reproductive prime would benefit greatly from creatine. Creatine is considered, it's something called a carne nutrient where it is really found in animal products, mainly red meat, which is, that's where the name carne nutrient came from.

44:19So it occurs naturally in foods, foods. Yes. Which is the recipe for a great supplement. Yes. Okay. And when you think about it, let's talk about who responds most to creatine. Number one, individuals that are eating likely a low creatine diet. So vegan vegetarians can really benefit from creatine. Okay. Individuals that are tired. There may be evidence to support it seems to give people more energy and training, decreasing fatigue. Brain function could improve mood and improve just overall thought process. That's amazing. Yeah, that's pretty extraordinary. It is. And the safety profile. We know that there is a high safety profile.

45:10It's the most studied supplement in the supplement industry, correct? For 60 some years. You know, we talk a lot, like our last podcast, we talked a lot about muscle and protein. And that is a huge layer, right? You have to get that right. I recommend close to one gram per pound, ideal body weight. If you want to be plant-based, fine. If you don't want to be plant-based, fine. But really higher protein is better. You think about training, right? What are the training things that we have to do to optimize muscle? You have to lift. You have to do that two to three times a week. It's non-negotiable.

45:45You cannot replace it with walking. yoga is great but you really should be doing some kind of resistance training right yeah so this is the foundation and then i think the next level is we start to think about our environment our interaction with the outside world our relationship with light our relationship with feeding timing these kind of things that as we think about the greater complexities of a woman fertility these things, I think that we layer in appropriate and meaningful habits, like the time of day that you eat. I think that we can really begin to optimize our health. The most important organ from my perspective, when it comes to longevity is muscle.

46:30The more healthy muscle mass you have, the greater your survivability against nearly anything that's going to kill you. The more healthy muscle mass you have, the stronger, let's say the stronger you are, the greater your survivability. There's nothing more important. And it's the only thing that we can control. Isn't it also great for like menopause and PCOS? Yeah. So many things. It is the metabolic sink. When we have chronic disease, we have to think, okay, well, where does that start? The majority of chronic diseases are metabolic in nature. Yeah. Where do we push the envelope for metabolism?

47:12Muscle.

47:20Thank you for joining us on the Pursuit of Wellness podcast. To support this show, please rate and review and share with your loved ones. If you want to be reminded of new episodes, click the subscribe button on your preferred podcast or video player. You can sign up for my newsletter to receive my favorites at marilowellan.com. It will be linked in the show notes. This podcast is a Pursuit Network production brought to you by Michaela Phillips, Joel Contartese, Daviel Waldner, and Mackenzie Mizell. You can also watch the full video of each episode on our YouTube channel at Pursuit of Wellness Podcast.

47:55Love you, power girls and power boys i will see you next time the content of this show is for educational and informational purposes only it is not a substitute for individual medical and mental health advice and does not constitute a provider patient relationship as always talk to your doctor or health team daydreaming about fiori soft dreamnet fabric meet the halo essential wide like pant. Designed with Fiore's softest premium stretch dream knit fabric. Invest in your happiness with some of the most comfortable clothes on the planet. Get 20 % off your first purchase at fiore.com slash halo20.

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From the publisher

Ep. 198: This week’s mashup brings together powerful insights from Dr. Gabrielle Lyon, Dr. Andy Galpin, and JJ Virgin on one of the most talked-about topics in fitness: creatine for strength training. We’ll unpack why muscle is your most important organ for longevity, clear up the biggest myths holding women back from using creatine, and explore how building strength can transform your body, mind, and confidence. You’ll hear practical strategies for getting started at any age, from first squats to advanced lifting, along with surprising benefits for mood, bone health, and aging powerfully. Tune in for expert advice that will leave you inspired to get stronger and feel unstoppable.

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Show Links:

Boost muscle, strength, and focus with Bloom Creatine—formulated to support women’s wellness, workouts, recovery, and daily energy.

Strength Training Secrets for Women: Protein, Ozempic, and Aging Powerfully with Celebrity Nutrition Expert & Fitness Hall of Famer JJ Virgin

Dr. Gabrielle Lyon on Muscle, Creatine & the Links between H. Pylori & Acne | Part 2

Why Women Are Training Wrong: Fix Hormones, Build Strength & Recover Smarter w/ Dr. Andy Galpin Part 1

Topics Discussed

00:08 - Welcome & episode overview

00:58 - Why creatine matters for women (Ep. 133: JJ Virgin)

02:20 - Water retention concerns explained

04:30 - Finding the right creatine dosage

06:15 - Creatine & strength training for pregnancy and healthy aging

08:40 - Encouraging parents to lift weights

12:26 - Beginner strength training progression & foundational exercises

14:30 - Muscle quality vs. muscle size

18:24 - “Muscle mommy” movement & cultural shifts in women’s strength training (Ep. 165: Dr. Andy Galpin)

26:19 - “Strengthspan”, muscle mass benefits & brain health

30:15 - Creatine safety & performance vs. health

34:55 - Debunking bloating concerns for women

38:36 - Creatine for women: cycle, pregnancy & brain health (Ep. 163: Dr. Gabrielle Lyon)

42:30 - When to start & who benefits most from creatine

44:20 - Protein and training as muscle foundations

45:27 - Muscle’s metabolic role & chronic disease prevention

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