FDA Commissioner Makary & OMB Director Vought 7/22/25

11 Jul 2025 · 46 min

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Squawk Pod Episode Notes: FDA Commissioner Makary & OMB Director Vought (7/22/25)

Episode Overview In this episode of Squawk Pod, produced by Katie Kramer, key discussions revolve around public health, monetary policy, and political dynamics in the U.S. Featuring interviews with FDA Commissioner Dr. Marty Makary and OMB Director Russell Vought, the episode explores vaccine mandates, public trust in health agencies, and the Federal Reserve's management under Chair Jerome Powell.

Key Guests

  • Dr. Marty Makary: FDA Commissioner
  • Russell Vought: Office of Management and Budget Director
  • Megan Cassella: CNBC Correspondent

Main Topics Discussed

  1. Public Health and Vaccination Stance
  2. Dr. Marty Makary's Position:
  3. Celebrated 100 days in office, addressing rising measles cases and declining public trust in health agencies.
  4. Criticized vaccine mandates for young, healthy individuals leading to increased anti-vaccine sentiment.
  5. Cited a drop in trust in healthcare workers from 71% pre-COVID to 40% post-pandemic.
  6. Advocates for a risk-based approach to vaccinations, emphasizing evidence over mandates.
  • Key Discussion Points:
  • The importance of recognizing natural immunity and avoiding mandates that could alienate the public.
  • A push for transparency between government health policies and personal health decisions.
  1. Federal Reserve Management
  2. Russell Vought's Critique of Jay Powell:
  3. Accused Powell of mismanagement within the Federal Reserve, particularly regarding a costly renovation project.
  4. Criticized the Fed's monetary policy, claiming it has been too late and expensive.
  5. The discussion highlighted the growing tension between the White House and the Fed regarding interest rate policy.
  • Key Discussion Points:
  • Vought noted that the Fed is operating at a loss and needs to be held accountable for its spending.
  • Emphasized the desire for the Fed to lower interest rates to improve economic conditions.
  1. Economic Impact of Policies
  2. Tariff Threats and Trade War:
  3. Discussion of President Trump's announcement of a 35% tariff on imports from Canada, escalating trade tensions.
  4. Insight from Megan Cassella on the implications of these tariffs on U.S. consumers and trade relations.
  1. Jamie Dimon's Perspectives
  2. Financial Market Insights:
  3. JP Morgan CEO Jamie Dimon warned about underestimations in rate hikes and criticized the political landscape impacting economic policies.
  4. Dimon's comments reflect broader concerns about inflation and the U.S. budget deficit.

Key Takeaways

  • Public Trust in Health:
  • The drop in public trust in healthcare agencies is significant and linked to vaccine policies.
  • A balanced, evidence-based approach to health recommendations is critical for rebuilding trust.
  • Fed Management Scrutiny:
  • There is increasing scrutiny on the Fed's spending and management, with calls for clearer accountability.
  • The White House's stance on interest rates reflects broader economic concerns and political dynamics.
  • Political Landscape and Economics:
  • The interplay between health policy, economic management, and political agendas is complex and impacts market perceptions.
  • Discussions around tariffs and trade policy indicate a potential shift in international relations affecting economic performance.

Conclusion This episode of Squawk Pod underscores the intricate relationship between public health initiatives, economic policies, and political pressures in the U.S. The insights from Dr. Makary and Russell Vought provide a window into current challenges and priorities facing the nation as it navigates these multifaceted issues.

Host Credits

  • Produced by: Katie Kramer
  • Anchors: Joe Kernen, Melissa Lee, Becky Quick, Andrew Ross Sorkin

Tune in to Squawk Box on CNBC for more discussions or subscribe to Squawk Pod for daily insights.

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Transcript

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0:00Bring in show music please. Hi, I'm CNBC producer Katie Kramer. Today on Squawk Pod. Marty McCurry, head of the FDA, is 100 days on the job. A controversial few months for the agency, measles cases at a 33-year high, and public trust trending lower. If we have vaccine mandates for young, healthy individuals, we were going to see a rise of an anti-vaccine sentiment, and I think that's exactly what happened. We saw a tremendous loss in public trust. And the White House is mounting pressure on the head of the Federal Reserve. OMB Director Russell Vogt takes issue with Jay Powell's revamp of the Fed's HQ, as well as his monetary policy.

0:42At every step of the way, we have problems with regard to the management of the Fed. He's too late and he's incredibly expensive with regard to his building project. And we're going to get to the bottom of that. Politics makes strange bedfellows from who's in favor at the White House to who's in favor in New York City? And President Trump announces new tariffs on Canada. Something must have made him mad. Our Megan Casella with the latest. Vast expansion of the trade war on multiple fronts just in the past few days. It's Friday, July 11th, 2025. Squawk Pod begins right now. Stand by in three, two, one.

1:22Fuel, please. Good morning. Welcome to Squawk Box here on CNBC. We're live at the Nasdaq Market side in Times Square. I'm Melissa Lee along with Joe Kernan. Becky and Andrew are off on this Friday. So yesterday you were like, it just wasn't, it wasn't like. I needed a break. It was a lot of a good thing. Thought I'd give it. That's what it is. Too much. There's a lot of things. There's a lot. I've never done, but I never had too much fun or too much. Melissa. So one day off. Now you're back. Back. Ready and ready and ready to go into saddle. Perfect. Good. Welcome. Thank you for being here. Thank you so much.

1:58for being here in fact i'll wait for my edible arrangement um crypto prices they are soaring beyond that record said yesterday fresh records on bitcoin this morning look at that level 118 450 of four and a half percent ether up seven percent it has had a great week this week remember we talked to joe lubin earlier amazing and you know who everyone talks about is our guy that we usually you talk about for the S &P and stocks is Tom Lee. Tom Lee, yeah, because he's been a bull for a long time. But the way he is a bull, he's on here, and Bitcoin will be at 70, and he'll just, and I go, well, what do you think?

2:37And he goes, well, I'm expecting 120 to 150. Right, and you think he's nuts. And you think he's absolutely crazy. That's the way he was when it first went up to 20 ,000 years ago, and it dropped all the way to 3 ,000 or something. And he said, oh, I think we'll be back to 20 by the end of the year. And at one point before I got, before I got. But you became a believer. Orange-pilled. I got orange-pilled pretty early. But it was at$8 ,000. It went down to$4 ,000. But one of my purchases was at$4 ,000. Wow. Yes. So I had some at$4 ,000. Did you take profits? I sold a lot at$55 ,000. I still have pretty much.

3:12I still have them. I'm fine. I'm good. And I love them. It's tough to enter now. You can buy fractional shares. But if you're a long-term believer. If you're still a hodler, they've been buying all along. But I remember when he said it then, I asked him, I said, you're so good at it. Why do you delve in this? It's so much easier for stocks. And you're so good at calling short-term trends on the S &P. You know, why risk your reputation on this? What at that point was such a thing. He probably didn't view it as a risk. No, he didn't. He was so sure of his forecast. Crypto-related stocks, by the way, also catching a bid.

3:44We've got sort of the double whammy going of the crypto trade working. You know, the coins actually working. But also that core weave deal for Core Scientific, also raising the value of a lot of the Bitcoin miners out there. Core Scientific, of course, prior to being what it is now, was a Bitcoin miner. It's got a lot of compute power and those assets might be up for sale. So we're seeing nice gains pre-market across the board. President Trump announcing tariffs on imports from Canada of 35 percent. Something must have made him mad. I don't know what the latest is. Maybe Megan knows. They start on August 1st.

4:18Megan Casella joins us now from Washington. Any particular thing or just the, you know, slow walking the whole process? What did anything in particular spur this latest threat? Not that we know of yet, Joe. We might learn today, but we don't know exactly what sparked this latest Canada threat. But I'll say there were two big escalations overnight on the trade and tariff front from the president, Canada being the first one, 35 % on imports from Canada, which, by the way, the second largest U.S. trading partner and the largest buyer of American goods last year. Now, an administration official did tell me late last night that the exemptions currently in place for USMCA-compliant goods likely will remain, as will the lower 10 % tariff for energy imports.

5:05That would soften this a little bit, but still a significant escalation from the 25 % level where it is now to 35 % on everything else. I was told that decision is not final. And this does come, to your point, just a few days, I think two weeks, after the president was first angry about Canada's digital services tax. And then once Prime Minister Mark Carney pulled that back, then things seemed to be back on track. So we don't know what caused this one. The other big tariff threat overnight, though, is that President Trump also told NBC News he's considering raising the universal baseline tariff from the 10 percent level where it has been since April to 15 or even 20 percent.

5:43So that would mean everything U.S. companies and consumers buy from abroad would cost at a minimum an extra 20 percent in the form of tariffs. And if I can take just a step back, this week began with the president postponing that major July 9th deadline for the country-specific tariffs to kick in. It looked like a potential softening of his trade stance, or at least a delay. But since then, we've seen these new tariff threats for Canada and Brazil. Neither of them were facing the deadline before. a 50 percent tariff on copper, a potential 200 percent tariff on pharmaceuticals, and now a possible doubling of the baseline tariff.

6:18So, guys, a vast expansion of the trade war on multiple fronts just in the past few days. And enough to knock the market, I guess, off its balance a little bit, at least for today. But as we said, half percent moves after new highs yesterday in the S &P and Nasdaq. So time will tell. Everybody's waiting to see what happens. August 1st is coming. I can guarantee you that. It will come in a couple weeks. And then you know it's coming after that. August 2nd. And then eventually winter is coming. Are you a Game of Thrones fan? Oh, yeah. Winter. Winter eventually is coming. Let's get a nice fall, though, after this rainy spring.

6:57Wasn't it rainy? Rainy summer. Rainy summer. Thanks, Megan. All right. The White House campaign against Fed Chair Jay Powell is intensifying. OMB Director Russell Vogt said Powell has grossly mismanaged the Fed and suggested he had misled Congress about a pricey and ostentatious renovation of the central bank's headquarters. Vogt posted a letter to Powell on X saying that the project to renovate the Fed's headquarters could be out of compliance with the approved plan and may require the Fed to immediately halt construction. The Fed declined to comment on this letter, but OMB Director Boat will comment right here on Squawk Box.

7:36It's a crazy story. Yeah. It's for future Fed presidents? He's not going to be there, but does he want a nice digs for himself? I mean, it's weird. I mean, it's... It's a weird thing to... You know, in watching the administration, Harvard, Columbia, whatever, once you're in their bad, you know, in the line of... Fire. Yeah, yeah, line of fire, They'll find anything. And this is, they're overspending on the headquarters. NVIDIA, I thought this was interesting that I think, you know, Wong is, Jensen Wong is one of the most powerful, intelligent, amazing business people. Still got to go to the White House and say, hi, Mr.

8:21President. Still got to do it. Still got to do it. Jensen Wong met with President Trump at the White House yesterday. So Jensen Wong could be the most powerful tech executive in the world. He's still not the most powerful man in the world who people just have a hard time accepting that right at the moment. That's probably the bad orange man. And I'm saying that in a funny way because of the Trump haters. But this happened yesterday ahead of Wong's trip to China today. It's unclear what the meeting was about, but NVIDIA has been grappling with export controls on its AI chips. implemented by the Trump administration in April for national security reasons.

8:58President Trump highlighted Nvidia's stock gains on Truth Social yesterday, noting that Nvidia is up 47 percent since the tariffs were announced by Trump. Nvidia shares rose slightly in yesterday's trading, becoming the first company to close a trading day with a market cap over four trillion dollars. And just like Tim Cook and others, some of the what at times look like. Like capricious moves, maybe by by the Trump administration, still doesn't mean that you don't have to respond to those and massage, you know, go and actually try try to plead your case to the Trump administration to to look at all the angles of what's going on.

9:45And I would do it, too, if we needed something. Right. And Huang has been very critical of those export controls. He's been very outspoken, not shying away from making those criticisms because they are effectively shut out of the China market. To the advantage of the Chinese domestic players like Huawei. Right. For every chip taken out of the system in China made by Nvidia, Huawei steps in and sells its chip. Right. Huawei has the advantage here. But but Wong has benefited also because he he got all those deals in Saudi when they were in Saudi Arabia. He was cited by President Trump, lauded there.

10:21But and so he sees what being in good graces can do for the company. And we've seen President Trump. He can be very certain about something, but you could go to him and make a case for something. And he's not, you know, he's not so stubborn that he doesn't all of a sudden say, you know, I was talking to gents. And then especially if he likes a guy talking to him. And, you know, he's right about we've seen that in other areas where he's he's will go 180 degrees back to something else. Tick tock, for example, even crypto, for example, he was anti crypto. This is years ago. Jamie Dimon, we're going to tell us what he's talking about.

11:04Did you see his comments about the mayor? Oh, my God. I'm assuming. You said the mayor. I know. The possible mayor. Not yet. He's not the mayor. I'm worried. A lot of people work against that. I know. But at this point, he's on polymarket everywhere else. But we'll talk about Jamie Dimon's comments about Zoran Mamdani. Can we call him Zoran? Is that too much to just call him Zoran? Like Madonna? Or no? J.P. Morgan CEO Jamie Dimon spoke at an event in Ireland yesterday. He said he thinks the financial markets are underestimating the possibility of U.S. interest rates climbing higher. He said the market is pricing at a 20 percent chance of higher rates, but he sees a 40 to 50 percent chance and called it a cause for concern.

11:46Diamond said his higher probability was based on price pressure, citing tariffs, as well as the U.S. government's migration policies. He called the U.S. budget deficit inflationary, but Diamond also said the real time data on the U.S. economy is totally impossible to read. And in the past when he said things, he discounts the idea that the economy isn't doing well in terms of just what we see with the consumer. And he would know because he's at J.P. Morgan. I think he looks at our balance sheet like as a bank, as a risk averse banker would look at any balance sheet. And then we've got problems with 37 trillion in debt.

12:25Everybody knows that. But with all that said, so now he thinks the possibility of rates going up is 40 to 50 percent. Because of inflation. Right. 40 to 50 is still that means it's 60 to 50 that rates go down. What he said about Zoran Mamdani, he called him, sharply criticized the candidate, calling him more a Marxist than a socialist and warning against supporting his candidacy. He also argued that the platform includes things like rent-free, free public transportation, city-run grocery stores, reflects the same, in his words, the same ideological mush that means nothing in the real world. So I don't know how many billionaires or leading businessmen you want criticizing this guy because that just makes his supporters say, see, he's right.

13:21Richie Torres yesterday, who I think is smart and, you know, as far as Democrats goes, he's not going to go. I like Richie Torres. He said something like, I guess, Mom Donnie put him on a list of people to be primary. And he says that's a badge of honor for me. Well, we'll see. I mean, money makes a big difference in politics. And right now does it. So you think 50 million puts Eric Adams back in the merits, 50 million additional dollars. Because right now there's a lot of money being raised for any anti-Mamdani candidate. Right, right. Cuomo had 20. Where'd that get him? Right. That's true. But you can make the case that Democratic primary is not representative of Democrats voting in the New York City broader.

14:07People make that case. Yeah. They know that it is. That this guy, look at Polly Market. I mean, it could be, suddenly Mayor Adams has a little bit of momentum, maybe. Yeah. But they are lining up. They're not lining up behind Cuomo, which is weird. But if Cuomo and Adams go in together, then it's going to be very difficult. Cheese will be next. Coming up next on Squawk Pod, FDA Commissioner Dr. Marty McCurry. He's been in the job 100 days, and he is the key regulator when it comes to enforcing the Make America Healthy Again agenda of Cabinet Secretary Robert F. Kennedy Jr., the nation's top health official.

14:46The promise of the Secretary Kennedy is to let people know that vaccines will be available if people want them. You will be able to get a vaccine if you want them. So that's a decision between you and your doctor.

15:02Welcome back to Squawk Pod. I'm producer Katie Kramer. The COVID-19 pandemic, now five years from the depths of the crisis, five years changed the very nature of public health in America. All this time, past social distancing, masking, and vaccine mandates, a new agenda has been ushered in with Donald Trump's return to the White House. Secretary Robert F. Kennedy Jr. of the Department of Health and Human Services is known for some skepticism towards chemical interventions in food and health care. And his approach to all vaccines, not just those to prevent transmission of the COVID virus, can be complicated.

15:37One of his key deputies is our next guest, FDA Commissioner Marty McCurry, responsible for the safety of what goes into our bodies, food, drugs, shots. He spoke about his approach as a regulator and much more with Joe Kernan and Melissa Lee. Joe kicks things off. Good morning, doctor. Good morning, Joe. Maybe you've been on a few times. I don't remember, but we all went through that period together, obviously. And there's a lot of look back now at that period. You know, it's a hot button issue. And sometimes it's tough to talk about. and there's conspiracies and controversies. I think of Novak Djokovic.

16:19Right now, he's going to be in the finals, I think, at Wimbledon. And at the time, I wondered about his decision, the decision of tennis. What do we know now, Doctor, in your view, about what we should have done with COVID? Should healthy people have been, not forced, but strongly coerced to take that? At the time, I thought it was a game changer and a lifesaver. Well, look, Joe, I had said during the time of the pandemic that if we have vaccine mandates for young, healthy individuals, we were going to see a rise of an anti-vaccine sentiment. And I think that's exactly what happened. We saw a tremendous loss in public trust.

16:59A study in JAMA found that 71 percent of people trusted their doctors and hospitals before the COVID pandemic. That's down to 40 percent. That's a 31 point drop. And I think it was from ignoring natural immunity. I think it was from vaccine mandates insisting that soldiers and firefighters and teachers be fired if they don't have the vaccine, even if they were young and healthy and had the infection already. They had circulating antibodies that could neutralize the virus, but they were antibodies the government did not recognize because it failed to recognize natural immunity. So we lost a lot of ground in public trust.

17:36And we're trying to rebuild that now through radical transparency and being very honest and telling people the government is not your doctor. Talk to your doctor and get good advice from your doctor's wisdom and judgment. There are some changes at the Vaccine Advisory Committee that a lot of hand-wringing and consternation about the new members. Is it anti-vax? Doctor, would you say? How would you describe your approach to preemptive disease management? Look, I think over at CDC, a different agency, they do have a reconstituted ACIP committee with a diversity of views. among people who do believe that vaccines save lives.

18:19The past committee had pushed for COVID boosters in young, healthy people. And of course, that is probably why we see such a backlash today. There was never great evidence for repeat boosters in young, healthy children. As a matter of fact, there was a myocarditis risk that was largely downplayed in young males. And I think if you look at the track record of that committee, there's a reason why 85 percent of health care workers did not get a COVID booster last fall. So we are taking an evidence-based approach. Dr. Vinay Prasad and I outlined it in the New England Journal of Medicine. And we're basically saying that there's got to be a risk stratified approach that is high risk versus low risk.

19:00Does a healthy 12-year-old girl today need another 60 doses in her average lifespan? That is a scientific unknown. And we'd like to see a clinical trial before approving the vaccine for that reason. How does removing the recommendation, though, increase choice, increase the patient's ability to come to a decision with doctors? Since so many insurance plans and programs depend on ACIP and CDC recommendations in order to provide the no cost, low cost vaccines, isn't this removing choice effectively from patients? Now, the promise of the Secretary Kennedy is to let people know that vaccines will be available if people want them.

19:42You will be able to get a vaccine if you want them. So that's a decision between you and your doctor. And each individual insurance company has their own policy. Look, some insurance companies don't pay for important cancer treatments that I, for patients that I saw as a cancer surgeon. And so that is another entire issue that's unrelated to the FDA. Okay, so the fact that private insurers, employer-sponsored insurance plans, Medicare Part D, Medicaid, the Vaccines for Children program, all of them link providing no-cost vaccines to CDC and ACIP recommendations. That removing the recommendations doesn't remove in some way the choice that patients can make, especially the vulnerable patients who may not be able to afford to pay.

20:31That's right. It does not remove the choice. And our job at the FDA is, and this is a charge by Congress, is to look at applications that are submitted to us and determine what is safe and effective. And so that is what we are committed to. I think there was some lost trust in the FDA when there was a new policy that basically said for a young, healthy, 15-year-old boy, we were going to rubber stamp a COVID vaccine without a clinical trial every year in perpetuity and the kid must get it. And I think we're saying we're going to be less absolutist when there's no evidence. I think the most dangerous thing you can do in public health is to demand something of a young, healthy individual when the evidence is just not that supportive for a new virus that creates a new protein and a new vaccine that creates a new protein where we haven't had a clinical trial in over four years.

21:22And those results in children were mixed back four years ago. The basic tenets of MAH, of Maha, or Make America Healthy Again, it seems to be it's proactive health care versus reactive. You'd have to do that with children, I think. And I immediately think about, as a country, our levels of obesity are just much higher than they need to be or should be. What does tackling that entail? And how does it play into these new drugs? And whether you really start, I don't know, is that what we need to do to all our kids? If we go V or Ozempic or something, doctor, or what's the answer? Is it foods? Is it additives?

22:09Is it the secretary has a lot of ideas? Yeah, it's all of the above, Joe. And we've not been talking about root causes in health care. I've been in academic medicine and been at all the major institutions giving grand rounds. We don't talk about root causes. We don't ask, why do 40 % of our nation's children now have a chronic disease? Why do a third of our nation's children now have prediabetes or diabetes? We've got to talk about school lunch programs, not just putting every six-year-old on Ozempic. We've got to talk about environmental exposures and chemicals in the food, not just chemotherapy.

22:46If you look at the types of cancer that are going up in young people, they are the GI cancers. That is the organ that interfaces with what we eat. So we've got to look at all the chemicals. We are doing an inventory of the 1 ,000-plus chemicals banned in Europe that appear in the U.S. food supply. You saw our action to remove all nine petroleum-based food dyes from the U.S. food supply. By next year, we're getting tremendous participation by the food manufacturers. We are looking into baby formula innovation. That recipe the FDA issues hasn't been updated essentially in 30 years. We need more innovation.

23:22Moms want baby formula without added sugar, without corn syrup, without seed oils. We need more innovation. It's been a regulatory failure. And we're asking the big question, why does it take 10 years for a drug to come to market? I mean, that is a giant existential question. And we're going to have to challenge deeply held assumptions to answer it. So we announced our program to reduce animal testing and replace it with computational modeling and organ-on-a-chip technology whereby drugs can be tested on cell culture medium in a lab with cells from the liver or heart or other organoids. We have a priority pathway now to pilot.

24:01Can we get a decision out in weeks instead of a year once that final application is approved? Can we run more continuous trials? and can we use AI more in the review process? We now have AI agency-wide for our reviewers. And yesterday we announced we're gonna make our decision letters, including rejection letters for drug public information so companies don't spin the results and developers can see exactly how the FDA thinks. And that's part of our radical transparency agenda. I wanted to talk to you, Dr. McCary, about the national priority vouchers, which does aim to speed up the approval process after a final drug application is submitted to get it down to one to two months as opposed to 10 to 12 months for national priorities.

24:47What qualifies as a national priority? I mean, you know, let's say there's an obesity drug that's even better than the ones out on the market. Is that a national priority for for the FDA to consider an expedited process? What falls into the category? Great question, Melissa. So it's a large unmet public health need. It is a priority identified as part of a U.S. domestic national priority, like the domestication of manufacturing as a national security issue. And look, the president is very adamant that he would like to see lower drug prices for Americans. And he doesn't like it that Americans are getting ripped off with drugs that are two, five, ten times higher in the United States than in London or France or Germany, other OECD countries.

25:34So we are including the affordability of drugs as a national priority. So we have a committee that's set up that will determine which products and companies will get these vouchers as a part of a pilot. Look, we've got to try new things. We've got to ask ourselves, why does it take so long for a cure to come to market? And we want to see more cures and meaningful treatments for Americans. We want to see big data used so we can have eyes on a drug immediately after approval and not just wake up five years later and say, hey, Vioxx may have killed 38 ,000 people. Maybe we need to take action. Or opioids may have killed nearly a million Americans 19 years after the approval of OxyContin.

26:17We're going to be having an incredible post-market surveillance program where we monitor drugs immediately after approval using big data and the cloud. And if we do it well, it can actually change the threshold for approval, especially when it comes to rare diseases. Can you give us an example of a health crisis right now? Just so we have an idea of what sorts of drugs, what sorts of companies may be seeking to use this national priority voucher program. You know, one of the cool things, Melissa, in this job is you get to see potentially promising treatments that are in the pipeline. And I'd like to see a cure for type 1 diabetes.

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26:51I'd like to see more cancer therapies that apply to stage 4 metastatic disease and cancer therapies that result in what we call in medicine a complete pathologic response. That is, the cancer melts away. There already appears to be some therapies that may enable cancers to go shrink and go away completely. That is, be eliminated without chemo, surgery, or radiation therapy. I'd like to see a universal flu shot so we don't have to try to guess each year. which strain is coming. There are candidates out there. And I'd like to see treatments for neurodegenerative diseases and other disabling diseases.

27:30I had an aunt who died of Alzheimer's disease. I'd like to see more in the neurodegenerative space. A lot of angst and panic about layoffs at the FDA. Was it bloated? Did it need restructuring? Is 15 % a big number in terms of layoffs, doctor? Because there are some people that say it's going to safeguarding the drugs that come into this country, manufactured elsewhere, are at risk now. There's not enough people to monitor. What do you make of that, that criticism? That's not true. So there were no layoffs to scientific reviewers or inspectors or our law enforcement division at the FDA. You know, we do inspections around the world, and we're leveling the playing field on that front.

28:20But there were early retirements, and so we're actively hiring scientific reviewers. Normally, there's a vacancy rate because there's a turnover in scientific reviewers, but no scientific reviewers were laid off. There were tremendous redundancies in the empire-building culture, the fiefdoms of the centers at the FDA. and they became their own independent organizations and they had very little accountability. They had their own revenue stream from user fees and they had redundant services as a result. That is, we had 12 different travel offices. We had nearly 2 ,000 HR person people and budget and procurement staff.

29:00And a lot of it was just because of the center fiefdom culture. So we've consolidated that now to say, if we're gonna launch AI for the FDA reviewers as we recently did, we're going to do it agency-wide. It's not going to be each center independently with their own IT teams coming up with a product. Just look at our adverse event reporting systems. They are so clunky, Joe. We have one for vaccines called VAERS, one for devices called MOD. We have VAERS and CARES and FAERS and Sentinel. We have 10 different adverse event reporting systems all sort of independently developed. We're going to go to one.

29:39And so that way we can have a great user interface and a great database of adverse events that we can use for our post-market surveillance of drugs. Doctor, I also wanted to ask you about your quest to make the FDA more transparent. And part of that was yesterday releasing more than 200 rejection letters, as you had mentioned before, to the public. So the public can actually see why a drug was rejected as opposed to getting a press release from the company, which may or may not give the full details or may have spin involved, etc. The letters were from 2020 to 2024. And investors, at least, are wondering if it's going to be more real time, because that's the only way it's really going to be useful.

30:22Yeah, let me be clear, Melissa. It's going to be real time. That was just the initial batch because we need time to do the human redaction of those letters. So I know some media outlets were, you know, hours after our announcement saying, oh, some of the, you know, this is only part of the stack of all the letters. We have thousands of letters that we are redacting. We're going to make them public. Drug developers and inventors are going to be able to go through them and see not just how the FDA thinks, but how one study section of the FDA thinks, the study section of interest. And we're going to be releasing them in real time as we make decisions.

31:00And that way, shareholders will be able to see exactly what the FDA said. Look, markets like predictability. And I've been doing a CEO listing tour. We're about two-thirds of the way through. It's in seven cities. And when we meet with pharmaceutical CEOs in private, That is where they can be open and honest about their ideas for reforming the FDA without their shareholders listening. They tell us they want more predictability. They want to know exactly how the FDA thinks and they want better communication. So they can, you know, one CEO said, if we could just have a couple 15 minute calls with the FDA review team along the process, it could save us nearly a year of doing things just out of guesswork and trying to figure out what the FDA wants.

31:45So we're going to be radically transparent. When can you come back? I love your show. I'd like to see fewer direct-to-consumer drug ads on your show, but I love your show. I was just going to ask you about that. I was going to say I want to talk to you about that because I still want this purple pill that's on nightly news every night. I don't know what it does. I have no idea. But they make me want it so much. I've been bugging my doctor. Give me that purple pill. I mean, it's crazy, doctor. Why do we need, if your doctor needs, if you need something, does the doctor need to be sold on something on TV for him to prescribe or her to prescribe the right thing for you?

32:28What's the whole rationale behind all these things? I don't even, all I know about are side effects I never want to get all over my body. That's all I know from these things. And I see people, you know, overweight people marching along the street. Where are they going? What are all these things and why do we need them? Yeah, they're always singing and dancing. They're always singing and dancing. And we have a regulation at the FDA. And I know sometimes you're at home, totally healthy. You just get back from the gym and you're watching these ads nonstop. And you want to say, OK, I give up. I'll take it.

33:00I'll take it. I don't know what it is. I don't know what it is. But I don't want it. Look, there's a regulation that says there should not be a misleading impression from these ads. And so we're taking a hard look at that. I also want to talk to you next time about autism rates and whether it's environmental. It seems genetic. It seems the diagnosis are exploding. And what about and care? What about all the people that already are growing into adulthood? And that's even might be a bigger issue than trying to figure everything else out. What you know, there's there's a huge there's millions. There's millions that.

33:35Yeah. The entire medical establishment has only been talking about treatments. So now we've got to start talking about root causes and research on root causes. All right. We'll come back and we can talk. I know what that blue pill does, but the purple one, it just depends on the colors. Anyway, Dr. McCarty, thank you. Squawk Box coming right back. Next on Squawk Pod, the White House is doubling down on its critique of Fed Chair Jay Powell. First, it was a push to lower interest rates. And now it's Office of Management and Budget Director Russell Vogt, who's zeroing in on renovations, the expense of the Fed's new building construction.

34:11Nothing to do with his stance on rates. It's only about largesse. This certainly has to do with the fiscal mismanagement of the Fed, of which this is one aspect of it.

34:25This is Squawk Pod. Stand by Joe. His mic. Q. You're watching Squawk Box on CNBC. I'm Joe Kernan, along with Melissa Lee. OMB Director Russ Vogt is calling out Fed Chair Jay Powell, writing in an ex post that Powell has grossly mismanaged the Fed. Russ Vogt joins us now and we'll talk about the more maybe wide ranging issues in terms of, you know, monetary policy. Then we can get into. I said maybe, you know, if I could print money, Russ, you heard what I said, I might make Versailles. I mean, I'd have servants. I'd have I don't think I could overspend on my facility. But we probably don't. We probably don't want that.

35:10But let's talk about that after we talk about monetary policy. You think that there are political reasons that J-Pow and the Fed have not lowered interest rates yet? Well, look, the president's been very clear he's concerned with the tight policy that the chairman has had. He thinks he's generally been too late. That's our view. And we saw Chairman Powell, he was too late to recognize inflation, and now he's too late to lower rates. And the Fed has just mismanaged the institution. And we see that the extent to which they've been operating at losses for a number of years now is for the first time in their history.

35:49And then you just see a very practical example when you go to the nation's mall. You see the construction of this palace, in the words of one former official, upwards of$2.5 billion, massive cost overrun. And we want to make sure we have facts as to the largesse and the extent to which it's overrun and the plans keep changing. The testimony that he has on the Hill keeps changing. And I think it just points to the fundamental mismanagement of the Fed under the chairman. Right. Maybe. That just sounds kind of vindictive. And I'm not saying that, you know, everybody's perfect in Washington. But if you're mad at the Fed for not lowering rates and you, you know, you start looking at their at the what they're trying to do with their headquarters.

36:33It just, you know, I don't know whether that's a substantive. But here's what I worry about, Russ. Let's say you got a president who loves lower rates. I won't mention any names. Might have been like a real estate guy. Might have been someone who just really likes lower rates. if he had a complete dove that would follow everything he wanted in terms of interest rate policy, you criticize Powell for not raising rates, not recognizing inflation when he needed to recognize it. You're really asking for someone who's on permanently easy, who has that switch permanently on for lower rates. And you would have done even worse in handling inflation with policy like that a couple of years ago.

37:16No, I don't think that's the case. I think the president has been a great prognosticator of where we should be in terms of rates. But this is this is a very simple debate today about what is going on in the national. What's regarding what's going on with the Fed? If President Trump was in office a couple of years ago when it was obvious that rates needed, you really think you would have said the Fed has to raise rates? I can't imagine the president ever saying it's hard for any president to tell the Fed to raise rates. Remember what happened to poor the first Bush and Alan Greenspan? He blames Alan Greenspan for for not being reelected because he was too tight with monetary policy.

37:59The problem with Chairman Powell is he has been late at every turn. And I remember back during the Biden administration when we were seeing the warning signs. We were seeing the warning signs very early, potentially on this program from people like Larry Summers. We knew the spending was out of control. We didn't have inflation under the Trump administration. We developed inflation as a country under the Biden administration because of the excess spending. And for a chairman not to be able to look at the warning signs, the dark storm clouds fiscally that were occurring, and to be ready. And they keep calling it transitory.

38:35And then once we have a new change of administration, we no longer have inflation. It's time to lower rates. You have a problem there. But again, this is about the largesse and the fact that he has systemically mismanaged the Fed. And that is evident by what we're seeing with regard to this monstrosity, this palace of Versailles on the National Mall, in the words of a former Fed official. Yeah, I thought I came up with that. But I mean, I can still throw other things at you, Russ. At the same time the administration is arguing, President, how great the economy is right now. And we're the hottest country on earth and everything else.

39:19That's usually not a time where you need interest rate cuts. And there will come a time, who knows from what, where maybe the economy does slow. And then you'd like some dry powder. You don't want to blow your wad before you need to do it if the economy is percolating. So, you know, I'm not I kind of have some empathy for what the president is saying, because I think maybe we're too restrictive at this point. And we'd like lower debt service on this huge debt that we have. But then again, I could make the argument that the economy is in fine shape. And this is not a time where you need to cut rates, especially if the inflation demon has not, you know, had a stake driven into its heart.

40:05Well, again, from an inflation perspective, we're not seeing that. The tariffs have not led to inflation, as all the experts said that they would. We're cutting spending. We're reducing the deficit. The tariffs are bringing in incredible amounts of revenue,$3 trillion over 10 years and counting. Those are all figures that come from the pause from Liberation Day. So fiscally, we are very much on the mend. And our point is we want to see the benefits of a growing economy flow to all Americans. And I know that there are people who are still stuck in mortgages with high rates that they would love to go to a lower level.

40:43I would love to see lower rates to be able to improve our fiscal situation. I want to see the Fed get back to not losing money every year so we can actually get remittance to the United States Treasury and improve our deficit. So, look, at every step of the way, we have problems with regard to the management of the Fed. He's too late and he's incredibly expensive with regard to his building project. And we're going to get to the bottom of that. So would you have tweeted what you tweeted yesterday, Russell, if Jay Powell said, I'm on track, I'm on board for a cut at the July 30 meeting? I mean, is this completely motivated by your stance that he should be cutting rates and he should be more dovish?

41:29The president is a builder. He's horrified by the notion of cost overruns. I go over to the Martin building fairly often in my role as CFPB director, and you see this largesse. You see the artwork in the Martin building. You see the extent to which they just have built and built with no consequence and no conscience with regard to the taxpayer. And now it's overrun, and you get the sense that they're talking about the gardens on the terrace, the waterworks outside, the private VIP elevators. This is wrong. The American people should deserve better from their public officials. And he's made comments that would suggest that they have changed the plan that the National Capital Planning Commission approved.

42:20He can't do that. And so we have new commissioners. So this has nothing to do with his stance on policy. Nothing to do with it. If he were cutting rates, you would still call for this investigation. This is about the extent to which this building is incredibly expensive and overrun. And we're going to be able to do what we can to deal with that kind of largesse that is offensive for anyone going to the National Mall. And that's the kind of thing that our National Capital Planning Commission. So this has nothing to do with his stance on rates. Nothing to do with his stance on rates. This certainly has to do with the fiscal mismanagement of the Fed, of which this is one aspect of it.

42:57And we are going to zoom in over the last several days on this. We have new commissioners at the National Capital Planning Commission who are asking very tough questions as recently as yesterday to see what is going on at the Fed right now with regard to this building. Is it in compliance with the plans that were approved? Should the plans be reconsidered? That's the debate that we'll be having over the next several weeks as our wonderful commissions do the hard work of their oversight activities. And we expect responses to the letter that I sent yesterday to the Fed. Right. Just in closing, do you think that President Trump really wants an independent, an independent Fed and an independent chairman of the Fed?

43:40And if so, if he really does want that, would there be a time and I don't know what the circumstances would be where interest rates needed to be raised for whatever reason, for inflation or whatever? And do you think the president would would be OK with that at some point? Because it it just seems like most presidents want lower rates because they want a strong economy. Joe, that's not the that's not the debate that we're having. The debate that we're having is the president came to the office on behalf of the American people. And to the extent that the Fed has a lever with regard to the economy that it is not using that we think is appropriate.

44:17The president has a voice in that. And the president is articulating his viewpoint, his administration's viewpoint. It's totally appropriate. We're now articulating our view as regard to this building. And I only expect that to continue. But this is not kind of a metaphysical debate about the Fed. It's about should the Fed lower rates on one hand? And in my lane with regard to this building, is this building largesse? Should it be overseen and should it be potentially reconsidered at the Planning Commission? Which question or which Kevin do you like? I'll end with that. Those are all questions for the president.

44:53The president will make all those kinds of announcements at the appropriate time. OK. OMB Director Russ Vogt. Thank you. Talking about Kevin Hassett, obviously, and Kevin Warsh. I don't know whether they're the frontrunners. Scott Bessence in the mix as well. That's Squawk Pod for today and for the week. Happy Friday. Squawk Box is hosted by Joe Kernan, Becky Quick, and Andrew Ross Sorkin. Becky and Andrew will be back on Monday. Tune in any weekday morning on CNBC at 6 Eastern. Or get the best of our TV show right into your ears when you follow Squawk Pod, wherever you like to get your podcasts.

45:31We'll meet you right back here on Monday. Have a great weekend. We are clear. Thanks, guys.

45:43Thank you.

From the publisher

100 days on the job, FDA Commissioner Dr. Marty Makary discusses HHS Secretary Robert F. Kennedy Jr.’s complicated stance on vaccines and the future of public trust in American health care agencies. The White House is mounting pressure on Federal Reserve Chair Jerome Powell; Office of Management and Budget Director Russell Vought explains that he’s pushing the central bank on its monetary policy and, more recently, on its building renovations. Plus, President Trump is threatening a 35% tariff on Canada, and Jamie Dimon is speaking out on global markets and on NYC Democratic Mayoral candidate Zohran Mamdani.

 

Megan Cassella - 5:06

Dr. Marty Makary - 18:24

Russell Vought - 38:04

 

In this episode:

Megan Cassella, @mmcassella

Joe Kernen, @JoeSquawk

Melissa Lee, @MelissaLeeCNBC

Katie Kramer, @Kramer_Katie


Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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