#291: The Biggest Investing Stories and Stocks of 2025

18 Dec 2025 · 49 min · 18 chapters

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In short

2025 investing recap—AI “pick-and-shovel” winners, a major market shock from Trump tariffs (“Liberation Day”), and three standout stocks: best (Google), best biotech (Wave Life Sciences), and “turkey” (Oklo and MicroStrategy).

Guests

Emmett and Mike (co-hosts; no other guests mentioned).

Guest backgrounds

Emmett and Mike are long-running market commentators/podcast hosts; Emmett discusses biotech/AI infrastructure investing and stock picks; Mike focuses on market narratives and portfolio-level implications.

Key claims

AI infrastructure spending drove returns for suppliers (NVIDIA; memory/storage: Sandisk, Western Digital, Seagate, Micron; foundries: TSMC, Intel; lithography: ASML; cooling/server racks; energy/nuclear). Tariffs briefly erased trillions and pushed the NASDAQ into a bear market, but AI kept rallying. Google’s sentiment flipped from chatbot disruption fears to AI-driven monetization (Gemini, Cloud growth, YouTube strength).

Notable examples

NVIDIA +25% in 2025; memory stocks top S&P 500; Google up ~60% YTD; Wave Life Sciences WVE-007 phase 1 obesity results (fat down, lean muscle up, possible once/twice-year dosing); Oklo micro-reactors +3000% then regulatory uncertainty; MicroStrategy leveraged Bitcoin model down ~60% since July.

Written by AI. May contain mistakes. Listen to the episode to check what was said.

Chapters

Tap a time to open that second in VO

2025 Year in Review: AI Dominance

3:33 to 9:25

Discussion on AI as the dominant investment theme of 2025 and its market impact.

“We're going to go story of the year first.”

Liberation Day: Market Shock and Recovery

9:29 to 14:01

Exploration of the impact of Liberation Day and the inevitability of market recoveries.

“I think there's a very strong analogy between what we're seeing now today with AI and the foundation of Manhattan.”

Reflection on Past Market Events

14:01 to 14:40

Learn about historical market shocks and their transient impacts.

“We all grabbed our laptops, stuck it under our arm and went home to drink tea, watch telly and work from home.”

The Nature of Market Volatility

14:41 to 18:16

Understand how market reactions to political events can be fleeting.

“And while I'm not playing down the economic impact, the stock market impact was fleeting.”

Stock of the Year Discussion

18:17 to 19:00

Join in the debate about selecting the most impactful stock of the year.

“I mean, it's a very reductive scorecard.”

Introducing Wave Life Sciences

19:01 to 19:40

Discover the promising story of Wave Life Sciences and its stock surge.

“And you told me what you were going to go for, which we'll discuss in a few moments.”

The Potential of Weight Loss Innovations

19:41 to 24:26

Explore the breakthroughs in obesity treatment and their market implications.

“And I'm not going to go like super deep on these.”

Evaluating Risks in Biotech Investments

24:27 to 28:00

Learn about the risks associated with early-stage biotech investments.

“And for a start, the data is very, very early.”

Weight Loss Breakthroughs and Biotech

28:00 to 29:13

Discussion on the competitive landscape of weight loss biotech and its investment potential.

“So put it in your black book as one to keep an eye on Mike and listeners.”

Google's Stock Performance and Market Sentiment

29:13 to 30:25

Analyzing Google's stock performance and its narrative shift in the market.

Show all 18 chapters

Challenges and Recovery of Google

30:25 to 31:38

Exploring the challenges Google faced and its recovery in the stock market.

“actually going through this it's interesting nvidia is the only one out of the rest of them outperforming the Nasdaq at the time of recording.”

AI Developments and Google's Future

31:38 to 33:56

Delving into Google's advancements in AI and the implications for its business.

“And then a few factors came into play this year that basically just completely upturned everything.”

David Gardner's Insights on Google

33:56 to 35:44

Discussing David Gardner's take on Google as a long-term investment.

“caused Sam Altman to enact a code red over at OpenAI.”

Turkey of the Year: Oklo's Promises and Risks

35:44 to 37:46

Evaluation of Oklo, its valuation, and the risks associated with its business model.

“And frankly, I wasn't overly bought into what am I talking about?”

The Debate on Oklo's Future and Market Perception

37:46 to 42:05

Analysis of Oklo's potential and the market's perception of its future viability.

“So it's a 13 and a half billion dollar business with advancements and a great idea, but no reactor.”

MicroStrategy: The Turkey of the Year

42:05 to 45:43

A deep dive into MicroStrategy's business model and its risks in the cryptocurrency market.

“We're putting Bitcoin on the balance sheet stock.”

Reflections on MicroStrategy's Business Strategy

45:43 to 47:26

Discussion on the implications of MicroStrategy's financial strategy and leadership.

“And that's why it's my turkey of the year.”

Upcoming Christmas Break and Show Highlights

47:26 to 48:45

Hosts discuss the upcoming break for Christmas and plans for future episodes.

“I was like, you know, that was my entry into Bitcoin.”
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Transcript

Automatic transcript. May contain errors.

0:00Google's up about 60 % year to date. It's by far the best performance stock in the Magnificent Seven. Actually going through this, it's interesting. NVIDIA is the only one out of the rest of them outperforming the NASDAQ at the time of recording. Tesla is about level. Meta, Microsoft, Apple, and Amazon are all training it. Amazon and Meta by a good way. So this conversation is about kind of the complete 180 in terms of sentiment on Wall Street that Google has gone through. With 2025 kind of rubber stamping it.

0:32Emmet:hey emid how we get on good to see you mike how are you today i'm good i'm good i'm looking forward to this episode we're talking about for a while so we're kind of looking back on 2025 as a whole um so i gave you three categories to work on for this episode story of the year stock of the year and then the christmas turkey of the year so yeah perceive that however i want i only had a whole year to prepare for it and you gave me plenty of notice but when you suggested this morning we record the podcast a day early I was like ah now I know I had 350 odd days to get ready for this but anyway let's see how it goes folks because I think we've some very interesting conversations to have today Mike 100 % all right uh before we get into it though you want to ladies and gentlemen the final enrollment for Horizon at a massive discount to last year's prices or earlier this year's prices are available if you email frank at my wall street.com get it before it's gone forever and before we publish my favorite stock from nexus one two and three next week in horizon which will include a fleeting insight into the stock that i think is most likely going to 50x in my life and all long subscribers to horizon know exactly what stock i'm talking about but they will get an insight that i don't think they'll find anywhere else apart from that i've also started to prepare for the reincarnation of spotlight which i had to stop doing for a little while uh which is a video service where i review three of the stocks that i've bought in the service and every few months kind of go back and look at ones i pitched in the past to see what story is today.

2:18Emmet:And the first of those three in the next spotlight, which isn't going to go live till I suppose week one in January, is truly fascinating because I bought it as a wild card, which is a stock I buy in Horizon or a stock I buy in my life that I don't put onto the Horizon scoreboard because I believe it has an abnormally high risk reward profile, even higher than I usually go. And in the research I've been conducting in the last week or so, I have found a business or re-found a business that I really truly believe is the next Tesla in its field. So that's coming in early January for Horizon subscribers.

3:05Emmet:Anyway, what I'm trying to say is email frank at my wall street.com before the 22nd of december he'll send you a link to buy it and lock in on a price for a couple of hundred bucks as opposed to several thousand bucks so uh closing days of me hitting you with that pitch folks and we are very proud i'm very proud of the service and i'm going to keep going until success is apparent and there for all to see nice one okay Okay, so 2025, year in review. We're going to go story of the year first. I'll kick us off. Yeah, go for it. I think this is so boring. I'm kind of going on a little bit, especially seeing what you said for your three picks.

3:48I don't know what you're going to say about them, but I've gone way more boring than you have. But I don't think we can go past AI. But we're framing it in a certain way here. So AI, again, clearly the dominant theme of 2025. I think it's kind of salvaged the stock market, really, the AI trade. There's no way we can go on about the year and not talk about it. But in general, it's not really the stocks we were expecting to be the leaders, if that makes sense. So, you know, we've talked about kind of at length the level of CapEx, especially among the hyperscalers. So Google, Amazon, Microsoft and Meta have spent or expect to spend throughout the entirety of 2025,$400 billion on CapEx.

4:32that's four companies alone. Do you know what I mean? Almost all of it aimed at this AI infrastructure build out. But what's interesting is that apart from Google, these businesses have underperformed this year. You know, the market is concerned about ROI, the sheer amount of cash being spent. Of course, these businesses are like the few to have resources to do it. And they would much rather be caught spending the money now than be left behind. But they haven't been the beneficiaries of the AI trade in 2025. The ones that have been reaping rewards have been the pick and shovel plates, whether it's OpenAI or Google or Amazon or Facebook or whoever, that comes out on top in this race for AI supremacy.

5:07It doesn't matter for NVIDIA, who's happy to sell the chips to everybody. Do you know what I mean? And that's kind of been the core theme at the base of this AI trade in 2025. It's these businesses that have been enabling the infrastructure build-out, that have been essentially the receiving end of that$400 billion CapEx bill. They've absolutely dominated this year. Now, the first stop is, of course, NVIDIA. It has to be. You know, it managed to tag on another 25 % this year after going tenfold in the two years previous. It became the largest stock in the market ahead of Apple. It reached the first stock ever to reach a$5 trillion market cap.

5:38It's come down a lot since then. But still, it's posted three blowout quarters in 2025. Now, obviously, people didn't tune in to hear me say, did you hear NVIDIA is doing well? So let's go down the board at some of the other key areas. But they all represent the same theme here. And the first stop I want to make is the memory market. So we're rehashing what we've gone over already recently in the pod about two weeks ago, but four of the top five best performing stocks in the S &P 500 were Sandisk, Western Digital, Seagate and Micron Technology. All four involved in digital storage. It's remarkable, really.

6:12And then if you fly over to Korea to look at Micron's two competitors in the semiconductor memory market, SK Hynix is up over 200 % and Samsung is up nearly 100%. So just an absolute bar and burner of the year, of the year for the memory market industry in general. Going on then to more of the semiconductors foundries, the kind of the building blocks of the semiconductors. We have Taiwan Semiconductor and Intel, the companies that really, you know, they make the kind of Acme bricks that then NVIDIA or AMD, whoever else will buy off them and design them and make their own semiconductors from there, if that makes sense.

6:47Taiwan Semiconductor is up just shy about 40 % this year. Intel nearly doubled. Obviously, it had a huge investment from the industry, NVIDIA, the government. It's really hot stock, but it very much is positioned to bring some chip production back to the US in a big way. It's up nearly double, about 86 % when I checked it at the time of recording. ASML is another one worth mentioning, up about 40 % this year. It's now Europe's largest company as well. And when we talk about moats and single points of failure and a global reliance on one individual company, ASL is right up there alongside probably Taiwan Semiconductor.

7:26It makes what are called photolithography machines, which are used to print the circuits on semiconductors. So they're the world's only supplier of the most advanced type of these machines, the extreme ultraviolet lithography systems. and essentially the entire global chip industry relies on this one individual company. There's loads more we can go through. Cooling comes to mind. The demand for data centers for cooling racks has just completely blown this industry up. You look at the returns of Vertiv Hollins, Comfort Systems USA, both had huge years. Server racks is another one, Supermicrocomputer and Dell.

8:00Big beneficiaries of this increased demand. Energy, we can talk as well. We've seen nuclear stocks have a big year, Constellation, Vistra, to name a few. but it's just been non-stop and we could be here for hours listening out some of the returns that these niche industries have falling into what i find interesting is that it just doesn't really show any signs of letting up anytime so judging from the attitudes among the hyperscalers their commitment to spending big their unwillingness to come second in this race and and the resources that they have available to them they're just they refuse to fall behind on ai and if that means spending hundreds of billions right now, that's what they're going to do because they can.

8:38Do you know what I mean? And now they're even going into the bond markets to do that as well and to raise capital. So it's really interesting what's happening there. Just last week, BlackRock published a big report forecasting AI spending to accelerate from here. It specifically mentioned the pick and shovel plays, which is scary considering how much money has already been sent there. But it goes to show there's plenty of room left to run, especially for this AI trade in terms of the pick and shovel aspect of it. So for me, that's been the story of the year. I think it's where the best performing companies have come from.

9:10And it's just, yeah, it's been an absolute gravy boat for anyone involved in this kind of AI infrastructure build-out, which is crazy to say, because you could probably talk about that in 2024 as well. And it looks at maybe for 2026 too. So that's my story of the year. It's boring, but that's where the money is.

9:28Emmet:I don't think it's boring. I think there's a very strong analogy between what we're seeing now today with AI and the foundation of Manhattan. So if you take the year, I don't know when Manhattan was founded, probably around 1750 or something like that. But if you were buying up land in 1800 on the island of Manhattan, you were probably spending money hand over fist, but you had a foresight that most others didn't have. And the analogy for me is That's what we're looking at now. The Manhattan of the internet is being built and it's called AI. So these giants with nearly infinite deep pockets have decided we've got to go buy the land, even though we can't really absolutely define what this thing is going to be.

10:15Emmet:I'm sure if we stood in the middle of public central park in the year 1920, it was, well, there's no question. It was very different to what we see now, but it would have been very difficult to describe what Manhattan will be in the year 2025. Well, that analogy for me is strong for AI because we are looking at it. We're looking at the macroeconomic picture. It goes slightly microeconomic when you talk about the Mag 7 and whether it's Microsoft or NVIDIA or Google, or tesla or whoever with their absolute application of us of dollars for the build out of ai but you can go into smaller companies but what we are looking at here is it is the new industrial revolution and it will bring an awful lot of casualties but it is the creation of something entirely entirely different and i think it deserves to be the defining story of 2025 I never listened to any of our old podcasts, but I suspect it was the story of 2024 as well.

11:16Emmet:Does that ring a bell a bit to you, Mike? I think so, for sure. There was no ignoring NVIDIA in 2024, of course. But I do think more of the market's attention was focused on the big names in 2024, whereas 2025, they're happy to move away from Magnificent 7 towards these industrial players. We were laughing to ourselves like two episodes ago when we were talking about Western Digital and Sanders Corporation, and they're 50, 60-year-old companies that are beating out all the high-tech innovators and disruptors and all this faff, I suppose, that's behind it in the S &P 500 this year. So it is interesting.

11:55But you could talk about bubbles. You could talk about short-termism. You could talk about kind of cyclical nature of a lot of these businesses. And I think you'd be entitled to. But for now, looking backwards, 2025, I think it's definitely defined what we've seen on the markets.

12:14Emmet:Yeah, a bubble is a rally you missed, right? No, that's true as well. right well being as you went with ai and i fully think it's deserving to be the story of the year especially from our perspective i think there's another one um which we can't not say so i'm going to go with the other one which is uh the biggest shock of the year and that was uh liberation day in april or yeah i mean tariffs as introduced by president trump briefly very briefly erased trillions, not billions, but trillions of value. And it sent the NASDAQ market specifically into a bear market, which the annals of history will record as the main scare of 2025.

12:54Emmet:But even that event really became a subplot because we all know that markets rebound sharply. And as you rightfully explained, the AI party just kept continuing. And the reason that I'm picking Liberation Day or the Liberation Day crash, I don't think it's called that, is to remind everyone that in stock investing, shocks are inevitable. They just are inevitable, such as Trump's tariff plan. And recoveries are even more inevitable. They're just as absolutely certain the market will take a beating and the market will recover. And it's a bit like a toothache. When it's over, it's quickly forgotten or eaten bread is soon forgotten.

13:39Emmet:And the pattern of shock and sudden crashes is everywhere in market history. It feels like a lifetime ago, the COVID crash, I dread mentioning it and it was a once in a century pandemic that triggered one of the fastest bear markets ever, possibly the fastest bear market ever. The S &P dropped something like 34 % in a month. Volatility went through the roof. We all grabbed our laptops, stuck it under our arm and went home to drink tea, watch telly and work from home. 2018, and that's forgotten. That's like an old toothache. 2018. You're talking about, sorry, recoveries being inevitable. The bounce back from that crash.

14:21Fastest recovery ever. The best 50 days in stock market history.

14:27Emmet:Absolutely true. And even though Liberation Day, to the point, was the biggest global economic story of 2025, it almost feels like a forgotten chapter in the history books of politics. And while I'm not playing down the economic impact, the stock market impact was fleeting. There's always a fleeting shock that comes your way. In 2018, in Q4, there was this kind of everything is falling sell-off because there was fears that the Fed rate hikes and the US-China trade war sparked this really horrible drawdown. And there was talk of a recession. But who even remembers that? Like at that time, it was like, oh, the sky is falling down.

15:09Emmet:2011 the u.s debt downgrade and the downgrade and the eurozone crisis uh when the loss of when the usa lost its triple a rating do you remember that mike in 2011 no i don't yeah yeah well come yeah okay you've got an excuse and it combined well it combines fears it was combining fears that europe's sovereign debt crisis would break the eurozone and it sent the markets into this really brisk sell-off and of course we forgot that one there was something in 2013 called a temper, what was it? What was it called? It was called a taper tantrum, I think it was called, where the Fed was going to slow bond purchases, Brexit in 2016, you name it.

15:52Emmet:And my point that I'm trying to articulate is that the year ahead will bring shocks. Of course it will, as 2025 brought shocks. And as with the nature of shocks, we've no idea what they're going to be we don't know when they're going to happen but we also know that life moves on very fast and growth is inevitable function of life and markets and i think that for me the big story of the year was liberation day our president trump waltzed out on the walked out into the is it the rose lawn and he had the board yeah the big board it was quite entertaining as long as he didn't live outside of america but what's interesting about that as well and i always harken back to something Bill Mann said in 2024.

16:35It was at our Horizon members meeting. And he said, in anticipation of another Trump presidency, this was after the November election, he said, in terms of stock markets, maybe there'll be volatility, maybe there won't. But there's one thing that Donald Trump loves, and it's his scorecard. And for him, the performance of the S &P 500 is as good a scorecard as you can get for his own success. And when we're talking about Liberation Day, I don't think he realized how much of an impact that would have on global stock markets and especially the American stock market. And the fallout since has kind of been walking it back a little bit, you know, from the big board to what people have actually paid is a big difference.

17:19And he was bringing a lot of people to the table. But it just goes to show that I think he very much cares about stock market performance. If you listen to interviews recently, he's talking about the increase in 401k millionaires in America. And he's touting the performance of the stock market in a way that links it to his own success. And I think for the next however long he's in office for whatever it is, three more years, he will very much look to, I think, protect stock market returns. Even the way his conversations are going around the Fed chair coming in next year about interest rates. he's very interested in a successful stock market.

17:58And that goes a long way, I think, in terms of performance, however it may come, because we don't know, because there will be volatility. There will definitely be political volatility involved. But it harkens back to, yes, he does care about stock market performance and he has the powers to affect it in that way. So, yeah, I think... Yeah, you're right.

18:18Emmet:I mean, it's a very reductive scorecard. The S &P 500's performance is a reductive scorecard for a president, but it's there in history to be observed, rightly or wrongly. And in fact, when you look at big data of Republican versus Democratic presidents over the long term, it really doesn't matter, believe it or not, on the absolute returns. But that doesn't detract from the very point that of all the presidents in our lifetime, Donald Trump is the one who most wants to win. uh like capitalizing those letters win whatever win means that's what matters most to to president trump yeah okay so now we're gonna go stock of the year uh you can lead us off with this one because you've got a much more interesting one than mine set it up set it up for the people okay i'm gonna tee it up i mean like how can you pick stock of the year because like that was it last week the week before i spoke about western digital and sandisk and the ones with the greatest gain and we agree arguably it should be those ones you know yeah Yeah, well, we agreed we would discuss our favorite stock, you know, or at least the best stock.

19:25Emmet:And you told me what you were going to go for, which we'll discuss in a few moments. So I decided to grab two names for this and our next segment that I suspect most people have not heard of. So it's not necessarily my favorite. And I'm not going to go like super deep on these. But what I will tell you is I am for this particular business, I have been hit with a fairly big whack of recency bias because the story of the company I'm about to discuss really only happened a couple of days ago. And the business is called Wave Life Sciences, and it jumped from$7 a pop on the 2nd of December to over$21 a couple of days later off news of an innovation that is every bit as much part of the story of the mid-2020s as AI is, possibly an even bigger one.

20:20Emmet:So without now, I know you don't know what the company does because we had a quick chat before the microphone started rolling. So what other industry, Mike, is in 2025 almost as big as AI, but in a different industry altogether? I would have assumed gene editing just by its name. Is that correct? I think you're close. And the person serving the meal is kind of. You're very close. It's weight loss drugs. so okay okay yeah so in summary wave life sciences ticker wve popped as a result of a really unexpected and extremely strong phase one result for its obesity drug wve 007 so they've used their ticker and james bond's number so who could forget that but wve 007 is a treatment that has showed i I mean, a lot of people would look at GLP-1 and Ozempic and Wagovi, which I've mispronounced for years after speaking to a patient of it recently.

21:26Emmet:And I realized they're pronouncing it differently, but I'm sticking with Wagovi for now until I get that stuck in my mind. But we kind of looked at it and went, wow, that's pretty innovative. Like humankind now can lose weight by doing effectively nothing, giving themselves a jab. But this really has changed the game of weight loss. But what WAVE are looking at is something that's going to change it all over again. And the treatment has showed massive reductions in visceral fat and overall body fat after a single low dose injection with surprising twist that lean muscle mass increased. So, but hold on, there's more.

22:07Emmet:So let alone, does this drug result in fat basically exiting? but you'll be ripped you'll have big forceps on a washboard stomach and that is truly like a layer up or a power up of of i think what most people wish to achieve but even more disruptive is the possibility that the drug may only need to be taken once a year maybe twice a year far far more convenient than today's GLP-1 drugs, which require weekly dosing and also cause unpleasant gastrointestinal side effects. And as I mentioned in a previous show, I know a few people who've taken GLP-1 drugs with stories ranging from upset stomachs to feeling properly nauseous beyond the stomach and needing higher doses after a while.

23:01Emmet:I was talking to somebody who moved from one provider to another because it was twice as strong. So this WVE007 or 007 works through a different mechanism and it silences the INHBE gene to mimic a naturally protective metabolic profile. So patients showed up to an 85 % reduction in active and E, which was stained for six months. So this basically was what the medical professionals are looking for, for the promise of an ultra infrequent dosing system. A lot of people, I suspect, have looked at Wegovi and Ozempic and the Eli competitor and all those. What's it called? Manjaro or something? Manjaro?

23:59Emmet:and they're not too keen on the idea of having to jab themselves once a week. Nobody really wants that. A lot of people are fine with it, but I'm sure a lot of people will be like, I just don't know if I want to do that. So the thing about WAVE is that the safety data was really clean. There was no zero severe side effects or discontinuations. which really helped fuel this rapid wave of analyst upgrades and soaring price targets. So if you kind of heard it here first on Stock Club, folks, but as with any chemical, especially chemical, but that's being self-administered into the body, the excitement that's suddenly gone into this business comes with a very real risk.

24:41Emmet:And for a start, the data is very, very early. Phase one is just the first milestone of, is it three, four phases you go through to get a drug to market. um patient numbers are very small and wave remains a loss-making clinical stage biotech that's now valued far above its fundamentals which is kind of par for course a start um a pharma company a biotech company a crisper company really is not uh valued on on the fundamentals on the numbers you see in the balance sheet it's your your investors go in because they see a promised land of a revenue line in the billions tens of billions or even hundreds of billions and the company is betting heavily on this program as you can imagine it's raised 350 million dollars to fund this upcoming phase two trials which i'm sure wasn't hard to raise even though it's a third of a billion for a small company that has negligible revenue um you know when you've proven those things then let alone you only have to take one or two shots a year and let alone does the weight fall off you but your muscle mass increases this is kind of like the panacea um uh i don't want to call it a vanity panacea that's absolutely miscategorization but the looking good feeling good panacea and uh so they raised a third of a billion uh phase uh two is going to involve tests with higher doses and larger populations and each new data set in 2026 will be a binary event.

26:13Emmet:So binary one, phase one was, hooray, it worked. Nobody's hurt. No horrible side effects. These people lost weight, gain muscle, look good, one shot. So that's a massive big green light move to phase two. But if phase two brings an unintended consequence and something we don't want, the stock will dramatically fall. And I think, Mike, the broader significance is that the obesity market which is already enormous like to live in ireland in 2025 when i was a kid you went to you got a treat as a scarce reward in the form of sugar at a party or maybe a friday everywhere you go in ireland now there is uh low quality food that tastes delicious everywhere the streets every room you walk into so we are all kind of at war with the sugar rewards that were far more fewer fewer and further between in the 70s so we're looking at a world where obesity is as a secondary consequence of treats being everywhere is a massive problem and it's undergoing a technological shift as companies are developing alternatives to glp1 so we don't want to lose muscle like one of the other ingredients to longevity and living to an old ages muscle strength grip strength the ability to do press-ups and whatever else bone density bone density exactly so this this company wave appears to be on the front end the front of the wave if you excuse the turn of phrase for a power up on these glp ones it offers easier dosing um and it's it's early results hint at something that's genuinely differentiated but the path is long it's going to be competitive when we saw who actually how quickly we forgot was it novartis who came out with the with um osempic and very soon oh nord yeah of course nord nord of course yeah yeah europe speaks how quickly you forget so they all came to market um and now eli with their manjaro were saying it's the latest and greatest and best but the thing is it's hyper competitive it's a very very um sought after solution but for now wave and the reason i to wrap up the reason i chose the story is that i believe it's like a proxy for the story of weight loss breakthroughs and how biotech can create absolutely sudden and spectacular gains from a single promising experiment but equally carry the real possibility that the story is far from guaranteed as positive So we are now looking at a bit.

28:56Emmet:So put it in your black book as one to keep an eye on Mike and listeners. 007, better known as Wave Life Sciences. And I've chosen it as, what was our heading again? The best stock? well just your stock of the year it could be any interpretation of that i'm gonna give it that i'm gonna stick a yellow uh sorry gold rosette on its lapel and say you're stock of the year because you're gonna do glp one better we're gonna gain muscle and lose weight and only have to inject once a year if it all works out yeah no it's a good one because definitely i'd have to say weight loss has been a prominent story for for good and bad for eli lilly good and for nova nordisk bag but then it's also very defining of just investing in biotechs in general you know what i mean this company has a great idea and a promise but there's nothing there yet and there won't be nothing there yet a certification that you got through tollgate one but you also know that the amount of science technology and research behind this drug well it's the accumulation of everything we've learned in humanity into a single molecule yeah okay i went the complete other end of the scale i know you did this is why i decided i go with one that i think most of our listeners were like never heard of that that sounds a bit wild and i'm handing over to you for one everyone has heard of yeah probably the most boring stock i could pick for this but likely the most important in terms of say the overall effect on the stock market but also just 2025 as a whole and its story it's google so google's up about 60 year to date it's by far the best performance stock the magnificent seven actually going through this it's interesting nvidia is the only one out of the rest of them outperforming the Nasdaq at the time of recording.

30:33Tesla is about level. Meta, Microsoft, Apple, and Amazon are all training it. Amazon and Meta by a good way. So this conversation is about kind of the complete 180 in terms of sentiment on Wall Street that Google has gone through with 2025 kind of rubber stamping it. So it's been on the recovery since the end of 2022, where it had a horrible year. And that kind of coincides with the launch of ChatTBT. And for the first time ever, what seemed like a realistic threat to Google's search monopoly. Warren Buffett famously called Google the greatest economic moment in the world. Now, all of a sudden, we have this magic box that spits out results that are better than anything that Google has ever done.

31:14Do you know what I mean? So this was the narrative.

Read the full transcript

31:15Emmet:God, does Warren Buffett ever get anything right? Read a book, Warren. This is the narrative for the next two years around Google's AI chatbots, and in particular, ChatGPT. We're here to disrupt it. Stock got sold out. There was more to that as well. There was an ad slowdown, and there was a lot of stuff under the hood kind of happening there was antitrust cases the stock got sold off and then its first version of a chatbot barred uh do you remember that beyond its name it was disaster and kind of yeah i used it for a little while and only a little while a couple of days when this isn't working for me at all and so that all kind of culminated in trading as low as in the high teens in terms of the price to earnings ratio and overall you know at least in terms of sentiment and the wider perspective maybe not so much in results because results did like kind of power through for the most part by slight ad slowdown, feud is very much a risk.

32:02And then a few factors came into play this year that basically just completely upturned everything. And I wouldn't say come into play this year, but have fully developed this year. So it shirked off the ad slowdown narrative that factored into the stock's original sell-off. YouTube in particular posted an incredible year so far in the first three quarters. Search has shown no signs of slowing down, spiked the rise in chatbots. Google Cloud has been a big growth driver this year, obviously driven by AI demand. Quarterly revenue is about$15 billion and it's grown in the mid-30s percent. So it's an absolute monster.

32:34And this is the reality of investing in Google. Do you know what I mean? I haven't even mentioned Waymo yet. It probably isn't even worth mentioning in terms of a Google investment, because revenue from Waymo is never going to make a dent in the giant that is Google overall. But just in terms of visibility and proof of concept, it's been a huge year there. And very clearly, that's the current leader in autonomous taxis. On top of that, and there's an irony to this one in September, the DOJ rule that Google in this big, massive search monopoly case against it wouldn't be forced to divest Chrome or Android, which was what the government were hunting for.

33:09The irony, of course, being that ChatGPT and other chatbots were the first real competition it had since the Internet Explorer. So it kind of had a case of being like, oh, we're not a monopoly anymore. Do you know what I mean? And then last, certainly not least, is the rise of Gemini. So it's AI model that came from the disaster that was barred. scale to hundreds of millions of monthly active users it's tightly integrated into search and then it's new ad formats as well so it's clear that ai it's ai spending where it is not as much as where it's not as obvious in other companies it's clear that it's ai spending is actually driving both usage and monetization so rather than just crazy capex with nothing to show for it google is one of the few that you can see the results of all this money being spent in november then Gemini 3 was launched and comfortably outperformed ChatGPG 5 which actually reportedly caused Sam Altman to enact a code red over at OpenAI.

34:02Did you hear about this? Sent out like a kind of CC all urgent we're getting outperformed by Google. So yeah I think obviously there's stocks that have outperformed Google this year in terms of performance but none that have transformed the narrative in such a way whereas it went from getting bet up by AI and being disrupted to being the leading candidate now all of a sudden do you know what i mean it out completely outperformed its competition it's it's got so many it's always had so many quivers to its uh both to its quiver is that that statement uh strings to its bow strings to its bow whatever there's so many assets to it but um i just think i just just think in terms of probably the most important stock even in terms of value added to the stock market no one has matched that i'd say it's about one and a half trillion dollars in terms of market cap added in 2025 that's surpassed Nvidia this year so yeah Google's my stock of the year probably the most important outperformance of the year especially with the rest of Magnificent Seven struggling so yeah yeah it's also it was an easy one for me as well as it's best performance stock in my portfolio so I didn't have to find it

35:11Emmet:and a few weeks ago when I interviewed David Gardner on on the podcast and I asked him for his desert island stock he said something to the effect of eminent might surprise you that i wouldn't go for something that's high tech i would go for something well sorry he said i probably wouldn't go for a rule breaker i'd go for a rule maker um and he chose google so his desert island stock was google it's your story of the year and no one can argue with that i mean it truly is one of the most well it's touched all of our lives it's brought a measurable value to more or less everyone's life in the Western world every day of the year for now 20 years you know so um who who could argue with that as they say exactly okay I'm looking forward to the last section now your turkey of the year we're coming up to Christmas the kind of gaff the the stock you'd want to throw a bit of shade on however way you want to interpret this I'm sure you've interpreted it in such a way yeah I know when you said turkey of the year I presumed it was the opposite of the stock of the year but i i could i i after writing down a few notes on the two companies i picked i couldn't really say right which is the turkey and which is the stock of the year because they're both pretty um well let me push on because i as much as wave life sciences has popped from 721 books and fallen back down to earth by the way so the company i picked as a turkey, which may not be a turkey at all, because frankly, it may be pardoned.

36:40Emmet:Yeah, it might be pardoned. And frankly, I wasn't overly bought into what am I talking about? What is it? Is it good or bad? Because I like turkeys. Anyway, the one I went with and could, as I said, as easily be swapped with Wave 007 is a company called, and it's again, very little known, I think, called Oklo. Have you heard of Oklo, Mike? Is that the nuclear, mini nuclear reactor company? Exactly. It's a pre-revenue nuclear micro reactor developer whose valuation absolutely exploded Chernobyl style as investors latched on to the idea that its compact reactors could power the coming wave of AI data centers.

37:28Emmet:and the shares shares have climbed about 3 000 from five bucks and change towards the end of 2024 around october 2024 to 175 dollars in october just gone a few weeks back and they've fallen back to about 87 i should have been a lot clearer with my rules should i have been no hold on now wait okay there's more there's more there's more like so like the the reason i've chosen let me push on there is more so i mean today today is a third today uh the business is a 13 and a half billion dollar company with no commercial reactor no revenue and a massively long and incredibly uncertain regulatory timeline and approval process.

38:23Emmet:So it's a 13 and a half billion dollar business with advancements and a great idea, but no reactor. I mean, the three main reasons that the stock grew, it didn't grow for no reason. And there was the headlines that really poured fuel on the story during the year where the first was a notice of intent to award from the U.S. Defense Logistics Agency to supply nuclear power to the Air Force Base in Alaska, which sent the stock up about 20 to 25 percent in a day. The second thing that gave it a boost was executive orders and broader pro-nuclear moves from the Trump administration and the U.S.-U.K.

39:08Emmet:nuclear cooperation deal which i think you spoke about in a previous podcast see i was listening and both were framed really as fast tracking nuclear support to ai and data center growth and then the third reason that this business has undergone abnormal growth is a a lot of bullish analyst coverage emerging wed bush and bank of america have all called called oklo as a leader in next generation nuclear and they slapped on really aggressive price targets which i guess validated the story for momentum traders and it's also noah yeah i think you're varying the lead a bit here are you isn't sam ottman behind it correct oh he's one of oklo's earliest and i guess most visible backers yeah he invested in the company years ago years and years ago and he later helped bring it uh bring it public through a spack that he supported and even he was even oklo's chairman before stepping back to focus on open AI.

40:06Emmet:So clearly there's the halo effect there. Absolutely. And not only that, but if you are, say, a new, not energy provider, but close to it, you know, and there's the company that needs the most energy over the next 10 years out of anyone that's ever existed, who's also on the Stargate committee in terms of AI infrastructure build-out, makes sense there that, you know, there is the hype around this company. And I'd imagine OpenAI or Q &A once it does become commercially viable to get involved with it. You're absolutely right. I mean, traders are casually referring to it as Sam Altman's nuclear play, even though he's not a founder.

40:45Emmet:And he's certainly not involved in the day-to-day operations, but he very much has an interest in success. And as I said, it's now a$13.6 billion business. so i guess calling it a turkey is in through one lens preposterous because it's not like it's a beaten up bashed up business with a bad business model but what it certainly is is a company that hasn't delivered the stuff it sells and has a massive price tag and has to get through a whole load of regulatory stuff so while i i would i would say it very much has a promising future i don't believe that it deserved 3000 percent price appreciation in the year 2025 which is why i'm going to give it a turkey award um but the the real i guess the the real kicker is that i suspect it's going to succeed but i just thought hey what the heck i i barely understand what a turkey is so just discuss this stock because it sounds like i think i think that's fair enough it i think you i think you took your interpretation of it well it just needed explaining and yeah i think that's fair um yeah i know it's like it's funny you mentioned two stocks and neither of them have earned a red cent between that's right and they both promised something that you know i'd certainly double oh seven up their wave they they're promising something that i think all of us would want less fat more muscle but it wouldn't you have a year and then the other guys are delivering b2b something we all want which is cleaner more efficient power to keep these super data hungry warehouses going and are backed by one of the most prolific entrepreneurs in the world at the moment sam altman so they're both i think truly interesting businesses that might just be as recognizable a name as google or eli lily in 10 years from now but right now they are early they have had a run um and they promised something big and exciting and and that's the type of investments that i usually gravitate towards okay and i'm still not sure if you like the business or not but i'll go on i i i like the promise but i i certainly when i when i started scratching under the surface i i didn't like it yet but it promises to be something that's fair okay i went a bit more direct with my uh turkey of the year i do not like this company uh that is micro strategy oh yeah yeah yeah yeah exactly i'm not planning to dwell on this one too long But for those who don't know, MicroStrategy is the original.

43:14We're putting Bitcoin on the balance sheet stock. So much so that it became the entire business, essentially. It was originally an enterprise software business, and that does still exist technically. But the company is just a vehicle to buy Bitcoin. Because it's a public company, it can raise equity and debt to do so, making it a leverage bet on the cryptocurrency. So it actually traded at a significant premium to its Bitcoin holdings for the longest time, which was essentially the entire investment thesis around the stock. So, you know, if Bitcoin wasn't risky enough for people, they could invest in MicroStrategy instead.

43:49And then obviously people took it. If that wasn't far enough, there were levered ETFs and you could buy a 5x levered ETF on MicroStrategy that would amplify the returns of a stock that is already amplifying the returns of Bitcoin. So silly stuff, obviously, but this was quite a good strategy when Bitcoin was on its run and it was going up. Obviously, it would fall apart once momentum shifted and it did. So the stock is down 40 % year to date and 60 % since its all-time high in July. Meanwhile, Bitcoin is down about 4 % year to date and 25 % since July at the time of recording. Its market cap is now worth less than its Bitcoin holdings as well, which is a big deal because that was an entire investment thesis.

44:28so it has it doesn't have that premium on its holdings anymore and also because it now owns 60 billion dollars worth of bitcoin but has all these crazy loans that it took out to buy bitcoin they are going to come due it could end up being a negative catalyst if it has to start selling some of those bitcoins because i think it might be the biggest owner of individual bitcoin biggest individual individual owner of bitcoins in the world that we know of that we know of satoshi whatever his name is is out there somewhere but if it starts having to sell off these bitcoins to pay back its debt which it could lead to kind of a debt spiral if you know what i mean if it's selling its assets would devalue those assets then it has to sell them faster and faster it can't sell them fast enough and the whole thing goes kaput you know what i mean so it was a stupid business model to begin with i don't like your man michael saylor he's appearing on front of magazines as if he's the next warren buffett and he has all these complicated plans of how he's gonna raise equity to buy Bitcoin and raise debt to buy Bitcoin.

45:26And because he's getting the leverage on that, so much returns, blah, blah, blah, blah. And now the bottom is falling completely out of it. And it should never have been a public company. You know, if you want to own Bitcoin, do that. If you're a gambler, go on Paddy Power or DraftKings or whatever. This should not be a listed business on the NASDAQ stock exchange. And that's why it's my turkey of the year.

45:45Emmet:Yeah, I think it's a good one. And really putting on the spot, but any idea what they're meant to be selling? like i always knew there were a b2b sas company yeah just but it couldn't be i never had a night what doing what like you know what did their sales people project management stuff or oh yeah payment doesn't matter it's 60 digital advocates it's a bin it's a bin full of 60 billion quid worth of bitcoin right now yeah and it's trading at 52 billion dollars so that shows this the flip in market confidence and just the amount of holes like everyone knew it was a leaking ship but it It was just pure momentum.

46:21And now that momentum has flipped. And if you were in it, I hope you realized how risky it was when you weren't. Because I think a lot of people approach it that way as well. This was a gamble. And I like to gamble. And that's what I'm doing. I'm doing it on the stock market instead of on an NFL game. That's your prerogative. But I don't think it should be a public company. I think public companies should try to add value. They shouldn't just be trying to make this weird Bitcoin premium business model strategy work. So that's my Turkey of the Year. It could completely blow up in 2026 for all we know.

46:58Or it could completely rally if Bitcoin turns around again. But I don't think it's a public company. I think it's a weird holding asset that people can invest in. and it's abusing its status as a public company as it stands right now. Rant over.

47:16Emmet:And my mic was muted. Nice one, Mike. I enjoyed that. And yeah, I had buyer's remorse when I was looking at MicroStrategy a couple of years ago. I was like, you know, that was my entry into Bitcoin. But all I did was watch and I'm glad that's all I did because I'm with you. I'm not a super fan of Michael Saylor. not a uh an like i mean the fact that you can go a leverage on that instrument just to kind of is like no that's not the purpose of commercial enterprise we buy businesses that are out to create value for their customers for their teams for their shareholders this kind of broke that rule yeah yeah so yeah i did 26 2026 could be very interesting depending on even if bitcoin stays flat once those bills start coming due i don't know what will happen to that business yeah certainly won't be recommending it on Sock Club we might be talking about it but we won't be recommending it Four very interesting companies well worth the conversation today Mike I really enjoyed that so between Google and MicroStrategy and Wave and Oclo I couldn't even remember what I was talking about we have had a very interesting conversation next week is Christmas week are we going to be broadcasting Mike?

48:32we're not we're taking we're taking the week off i don't think anyone wants to listen to us on christmas day yeah i think we'll give people a break families do we'll give them a break i don't have to be listening to the table either but uh no taking christmas day off um we'll be publishing a highlights show on new year's eve new year's day what day is the first new year's day and then oh it's always the first every year you can set your watch five years day is always the first and then we'll be back with looking ahead to 2026 into the new year so emmett thank you very much for joining me thank you everyone for listening in if you are listening in and you've got this far please do give us an hour subscribe give us a like wherever you're listening to us on it does help the show and a very merry christmas we'll talk to you all in two weeks time instead

From the publisher

As the year winds down, Emmet and Mike look back on their favorite investing stories, stocks, and turkeys from 2025.

Mike touches on the obvious: AI and the “pick-and-shovel” plays that have ridden its wave. Chipmakers and storage manufacturers are among the market’s biggest winners. Even Intel, long the ugly stepsister of Nvidia and AMD, is up nearly 80% thanks to government investment and the push to bring manufacturing back to the United States.

Emmet discusses the fallout from the Liberation Day tariffs and the subsequent market rally. It’s an important reminder for long-term investors that sell-offs are inevitable—as are recoveries.

Moving on to stocks, Emmet covers Wave Life Sciences (WVE), the latest pharmaceutical company to debut a weight-loss drug. Unlike Ozempic and Wegovy, WVE-007 is taken once and does not impact patients’ muscle mass, sending the company’s stock soaring. However, the drug is still in early testing and likely years away from market.

Mike heads to safer waters, pitching Google. Despite a slow start, its latest Gemini 3.5 model has Sam Altman sweating, while its tidy collection of existing businesses keeps printing cash. Unlike OpenAI and Anthropic, it doesn’t need to focus on monetization, giving it a leg up in the race for market share.

Finally, we bring you 2025’s biggest turkeys. Emmet goes with Oklo, the maker of small modular reactors. Its stock is up 15x over the last year despite not yet having a working reactor. Mike picks MicroStrategy, the riskiest way to buy Bitcoin. It’s down 40% year to date, while Bitcoin is down just 4%—lovely.

Our Horizon portfolio is a boutique service led by our co-founder and lead investor, Emmet Savage. According to 100-bagger expert Chris Mayer, “no one owns more 100-baggers than Emmet”.

Horizon will be repriced to $2999 in 2026 but for a limited time, Stock Club listeners can grab an exclusive discount and lock in our 2025 price.

To get yours, email frank@mywallst.com

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00:00 Intro03:32 The AI Revolution12:28 Liberation Day and Market Shocks18:59 Stock of the Year: Wave Life Sciences30:11 Google's Remarkable 2025 Performance35:56 Oklo: A Market Turkey43:04 MicroStrategy: A Bitcoin Gamble

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