In short
Prenatal care and supplement “truths” (especially MTHFR and folate forms), hormone/muscle health, creatine for women during pregnancy, postpartum mental wellness (anxiety vs depression), and what “clean” means in supplements; also how to balance self-care with running a business and parenting.
Guest
Victoria Thain Gioia, co-founder and CEO of Parallel (an OBGYN-founded vitamin company). She’s a mother of four; her daughter was born with a cleft requiring four surgeries. She says she has an MTHFR variant and researched prenatal nutrition after that experience.
Key claims
MTHFR is overblown but can matter for folate processing; methylated folate (and other bioavailable forms) may reduce “body burden.” Folic acid was historically used to fortify foods because it’s heat-stable. Prenatal needs change by trimester; postpartum needs include depletion support. Creatine can be beneficial in pregnancy at safe doses (she cites 3–5g/day; she uses 5g). “Clean” is not regulated; brands should use third-party testing and certifications.
Notable examples
Her daughter’s cleft (genetic vs “construction” cleft tied to nutrition deficiencies); her own gummy prenatal missing nutrients; her postpartum anxiety described as intrusive thoughts vs depression described as dissociation/overwhelm; Parallel’s trimester-specific packs and third-party lot testing.
Written by AI. May contain mistakes. Listen to the episode to check what was said.
Chapters
Tap a time to open that second in VOUnderstanding MTHFR and Prenatal Vitamins
0:45 to 2:58
Exploring the MTHFR gene mutation and its impact on prenatal vitamin absorption.
“Some topics here are the MTHFR gene mutation.”
The History of Folic Acid in Prenatal Care
2:58 to 5:15
A deep dive into the history and importance of folic acid supplementation during pregnancy.
“Bayadi, who's our medical co-founder, and there's a reason why she is.”
Personal Journey into Prenatal Nutrition
5:15 to 8:02
Victoria shares her personal story related to her daughter's health and prenatal nutrition.
“And so as a type A millennial mom, when we were getting this diagnosis, meeting with the care team and planning surgery, after my 20-week scan, I started digging deeper and wanted to figure out the why.”
The Challenges of Motherhood and Self-Care
8:02 to 10:11
Discussing the struggles of balancing motherhood, business, and self-care.
“And she was just saying, like, if you do these things, you're going to have this.”
Surviving the Chaos of Parenting
10:11 to 12:16
Navigating the challenges of parenting young children while managing a business.
“and our youngest will be two this month.”
Balancing Business and Family Responsibilities
12:16 to 13:41
Victoria discusses the balance between running a business and family life.
“I mean, I mean, that's, we're just hanging on.”
Creatine Use During Pregnancy
13:41 to 14:01
Exploring the role of creatine in pregnancy and its benefits.
“And it's definitely been a shift over the last six months of like what I spend most of my time doing, but trying to balance it all.”
Importance of Supplements During Pregnancy
14:01 to 14:33
Learn about the necessity of specific supplements like protein and creatine during pregnancy.
“It's just I think there's some like studies out there that make it feel scary, but it's all about the dosage.”
Dosage and Safety of Creatine
14:33 to 15:22
Understand the importance of safe and effective dosages of supplements during pregnancy.
“And so you just need to make sure you're taking like the safe and effective dose during pregnancy and just talking to your doctor.”
Women and Supplement Awareness
15:22 to 17:33
Explore the historical context of women's engagement with supplements like creatine and protein.
“Thanks for telling me what you were doing since you were 12.”
Show all 25 chapters
Muscle Health and Aging in Women
17:33 to 19:12
Discover how muscle health impacts women as they age and hormonal changes they face.
“Like women have hormonal fluctuations, much more so than men.”
Insights from an OBGYN on Supplements
19:12 to 21:30
Learn how an OBGYN's perspective shapes supplement formulations for women.
“So a lot of people are like, oh, it makes you bloated.”
Routine and Tolerability in Supplement Use
21:30 to 22:40
Find out how to effectively incorporate supplements into a daily routine.
“And so we need to think of them that way, but it needs to be part of your daily routine.”
Nutrition Focus in Pregnancy
22:40 to 25:31
Understand the critical role of nutrition and protein intake during pregnancy.
“Knowing everything that you know now, because obviously you've been around the right people and done your research.”
Postpartum Nutritional Awareness
25:31 to 26:11
Discuss general nutrient depletion postpartum and the role of folate.
“I haven't heard that as much as in the postpartum period.”
Defining 'Clean' in Supplements
26:11 to 28:00
Unpack what 'clean' means in the supplement industry and the importance of testing.
“What does that actually mean in the supplement and protein world?”
Understanding Heavy Metals in Supplements
28:00 to 29:40
Learn about the importance of third-party testing for supplements and how heavy metals can affect prenatal care.
“So So if a supplement says they're free from heavy metals, it may be true, but it probably means that they don't have critical ingredients, especially in a prenatal.”
Postpartum Anxiety and Depression Insights
29:40 to 30:50
Discover insights into postpartum anxiety and depression, including personal experiences and the need for awareness.
“So the third party testing is important when you're getting a supplement, it sounds like.”
Intrusive Thoughts and Personal Experiences
30:50 to 33:10
Explore the distinction between postpartum depression and anxiety through personal anecdotes and shared experiences.
“there's so much more to that conversation that can be pulled forward and like people talking about that.”
The Emotional Rollercoaster of Pregnancy
33:10 to 35:20
Understand the emotional complexities pregnant women face, including hormonal changes and feelings of depression.
“And I think a lot of partners in the, like I remember for me and not, it wasn't about me, but I, I hadn't, I just had no idea what was going on.”
Support During Pregnancy and Postpartum
35:20 to 37:30
Learn about the importance of partner support during pregnancy and postpartum recovery, backed by personal stories.
“Like, of course, like you're out of your mind.”
MTHFR and Vitamin Considerations
37:30 to 38:50
Find out how to manage MTHFR mutations and the importance of taking methylated vitamins for better health.
“So if someone is listening and they have M-T-H-E-R-F-R.”
Cellular Hydration and Nutritional Needs
38:50 to 40:50
Explore the significance of hydration and nutritional needs for women, especially during pregnancy.
“body what it needs right away without having to turn it into a refinery.”
Challenges of Fundraising for Startups
40:50 to 42:01
Gain insight into the challenges of fundraising during tough economic times and how it shapes business strategies.
“So it's giving you all of that and it gives you your creatine and it's all in one scoop.”
Navigating Business Challenges in Tough Markets
42:01 to 43:35
Learn how to build a sustainable business model during challenging market conditions.
“And we're like, well, we can't, that's the whole thing.”
Transcript
Automatic transcript. May contain errors.0:01Michael Bosstick:Welcome to the Bosticks, starring Lauren Bosstick and Michael Bosstick. Together, they are the Bosticks. Victoria Thain Gioia is on the show. She is the co-founder and CEO of Parallel, the first OBGYN-founded vitamin company, offering doctor-formulated, research-backed supplements. I liked this episode as a mother because Victoria is a mother of four and she understands the whole landscape when it comes to running a business, caring about health, and also managing her children. So this conversation was very much relatable to me and I think it'll be relatable to you, especially if you're someone who wants to be pregnant, is thinking about getting pregnant, or maybe you are pregnant.
0:51Some topics here are the MTHFR gene mutation. We discuss the truth about prenatal vitamins, creatine for women, hormone health, postpartum mental wellness, and balancing it all as a mother and a businesswoman. Victoria, welcome to the show. Why are we seeing MTHFR everywhere? It's everywhere.
1:11Victoria Thain Gioia:I mean, in general, I think it's a little overblown, but because I don't know what you do with that information, except for say, okay then I should take a more bioavailable format because my body can't process folic acid in the same way but why doesn't everyone just take a more bioavailable format of folic acid which is methylated folate and so folic acid is the synthetic format and it requires everyone out of everyone that your body methylates it to convert it into folate so it's like folic acid has to be methylated into folate and then your body can absorb it. Or you could just start with folate.
1:50Michael Bosstick:I don't think a lot of people know that. And even when we just started talking about this, but we're clear now, and we've covered this on this show, if you have the MTHFR gene mutation, got it one time, then you cannot convert folic acid in your body, right?
2:09Victoria Thain Gioia:You can't do it as effectively.
2:10Michael Bosstick:You can't do it as effectively. Okay. Yes. So people know, okay, I got to take a methylated vitamin to do that.
2:16Victoria Thain Gioia:Yes.
2:16Michael Bosstick:But I don't think a lot of people realize you could just take, even if you don't have the gene mutation, you could take the methylated. I didn't know that.
2:22Victoria Thain Gioia:Yeah, because it's also just reducing the body burden. You know, we're taking a lot of supplements today. Like, let's reduce all of the processes our body has to make. And so across all different formats of ingredients, like take the most bioavailable format that has the fewest steps for your body to absorb them. So it's almost like, why is the stuff that's not, and I'm going to flub this, why is it not, why is it the stuff with folic, is it folic acid? Well, like I don't even understand why the other stuff's not on the market. So there's, so folic acid, it's like a history piece. So tell us the history.
3:01Victoria Thain Gioia:I'm not going to get it all right. That's okay. You know, Dr. Bayadi, who's our medical co-founder, and there's a reason why she is. folic acid was identified in like the 80s with its connection to birth defects neural tube defects most primarily but other birth defects as well like clefts and that's before sort of methylated folate was a new which is a newer ingredient and more advances had been made in the supplement category and then the second part of it is that folic acid is heat stable and so when these studies came out connecting folate to these birth defects and folate deficiencies to birth defects, the best way to solve it in mass, especially before like the supplement industry was as sort of widespread in the 80s, was to fortify our food system.
3:51Victoria Thain Gioia:And so with that, you needed something that was heat stable that could go into breads and pastas and cereals. And so that's why folic acid is the most talked about. And that's why and studies were done on folic acid. we're not going to redo those studies that would be unethical we're not going to have a control group of women that don't get folate or folic acid so they're never going to be redone with methylated folate but there are studies that have shown that methylated folate is as affected if not better than folic acid so but the wide studies that like really showed nothing versus folic acid aren't going to be redone again.
4:33And how did you become interested in this in the first place?
4:35Victoria Thain Gioia:This is niche. Yeah. Yes, this is definitely niche. My daughter, our second child, Imogen, was born with a cleft seven years ago. She is a beautiful, happy, healthy seven-year-old today, and she's had four surgeries. And that's not ever pain that you want your child to go through, but would never change a second of her. She had a cleft, and there's two different ways that clefts can form. We found this from our care team and our surgeons. There's the sort of blueprint clefts, which are genetic, which we tested for and it was not a genetic cleft. And then there's the second part, which is sort of the construction type, which is the formation clefts, which can be related to sort of external factors, one of which is nutrition and nutrition related deficiencies such as bollic acid.
5:23Victoria Thain Gioia:And so as a type A millennial mom, when we were getting this diagnosis, meeting with the care team and planning surgery, after my 20-week scan, I started digging deeper and wanted to figure out the why. And I didn't really have some of the other kind of external factors. So it seemed likely that it was a nutrition-related birth defect. And I then tested and I found out that I had the MTHFR variant. And so all of this kind of got me into this rabbit hole learning about folic acid and methylated folate, but more than that, like the prenatal vitamin category as a whole and what was in the market, what was serving women, and that's kind of the whole journey.
6:11Victoria Thain Gioia:And so that was a piece of it, but I think it was more so what was missing in the category in general. Just so I'm so clear on this, if you have MTFHR and you take a prenatal without the active form of folic acid, does that equal something happening to the baby or not always? No, no, no, no. And I really don't want to say that at all. And like, there are so many factors that can contribute to these types of birth defects. and I'm just asking from an ignorant I don't know yes yes and I but I just I do feel like that is something I really want to clarify because there's so many things like you have multiple kids too like so many things have to go right to have a healthy child which I didn't even realize until you start on this fertility journey and you start learning all about this and the ups and downs and And so there's so many things that have to go right.
7:08Victoria Thain Gioia:So no, it does not mean that at all. It just means that your body isn't properly processing it. I had other things going on. I had two kids back to back. I was taking a gummy prenatal vitamin that was number one in the market that was missing all sorts of other things, too. She actually has some calcium deficiencies. She has a couple of fake teeth. So I was clearly nutritionally depleted going into this pregnancy. and that probably contributed to some of these things, but it's not pinpointed on this methylated folate discrepancy. But this was something that I realized in the category and then kept digging in.
7:48Victoria Thain Gioia:There's more and more in the prenatal vitamin category that I learned.
7:51Michael Bosstick:We just had the glucose goddess on the show and she was recently pregnant and had a child and she was talking about just like the nutrition and the nutrition deficits when you're building a child in your body, right? And she was just saying, like, if you do these things, you're going to have this. If you do these things, it's going to be hard. And so she's just saying how hard it is. But like people are starting to talk about nutrition and supplementation more and more now. And I think for the longest time, there was a little bit of a like, oh, it kind of doesn't matter what you eat. And I got to be careful here as the man on the show.
8:20Michael Bosstick:But I think people are now starting to say like, well, it does matter. And you will have potentially different outcomes with different nutritional diets.
8:28Victoria Thain Gioia:Yeah, completely. And like going into a pregnancy, like being nutritionally sufficient, going into a pregnancy, how you prepare your body for the conception phase, too. Like there's so much more that you can be doing. And it's like we don't just need to be surviving a pregnancy. And like there can be optimal outcomes. Like a woman can be thriving. She can have energy. She can feel good. And supplementation is a key part of that. Do you feel so empowered by taking what has happened with your daughter and having such a big cause? It's almost like your daughter pointed you towards this. She's our muse and she knows that.
9:03Victoria Thain Gioia:And so she like feels this special connection to Parallel. She actually told me earlier this week they're doing like a Shiro project for their school for Women's History Month. And she told me that I was her Shiro. And I like truly cried. Yes, she's our muse. And like, I don't think of it as a, she would be any different, but you know, she started us down this road and we built something to support women that is so much bigger than this situation. And yeah, it's really cool. And I feel like recently we had one of her last in this sort of time period appointments at the children's hospital. And then like I went and saw it, we have 35 people on the team and we've like really built this business to support a lot of women.
9:48Victoria Thain Gioia:And I'm really proud of what we've been able to do out of this and for her. Is there anything that you've done during this process with your daughter over the last seven years that you feel like has really helped you as a mom? Yes. I do feel like self-care for the mom falls by the wayside, for sure. I have four kids. I run the business. You're just go, go, go.
10:11Michael Bosstick:How old are you? What's the youngest or tallest? No, oldest to youngest.
10:16Victoria Thain Gioia:Oldest, it's eight, seven, five. and our youngest will be two this month. It's chaos. Eight, seven, five, and two. Yeah. Yeah, you're busy. So what do you do for yourself? I really believe in like exercise. That's always been my de-stressor. I have high levels of anxiety. So carving out that time and like it is your phone free time. You can't be on your computer. You can't check your emails. Like you have to kind of put it down. So that's big for me. And that's like my non-negotiable. And it's always been since I was a kid, I used to be a big runner. So I feel like making sure I continue to carve that space has been my personal me time.
10:58Victoria Thain Gioia:And then just kind of like the general care.
11:00Michael Bosstick:It's okay for you to say you're just hanging on because I have these young, these guys that are my friends that are like, but they have no kids and they're just living their life. And they talk to me about their extensive morning routines and their wind down routines and these sauna cold plunge sessions and these dates they go on. And I got interviewed, was it yesterday by business insider or something like that i think and they were like well what is your routine i'm like listen i'm hanging on by a thread in the morning and at night i'm like barely getting in what i need to get in and i think for parents out there with young children scott galloway was on the show he's like oh you guys are in vietnam like and you don't really realize it when you're in it and again like people we're not the first people to be parents and you know many people do it under much harder circumstances but i think when they're in this pocket of this age where they literally can't put their pants on by themselves or feed themselves.
11:46Michael Bosstick:Like you're just hanging on doing your best. Yeah.
11:48Victoria Thain Gioia:Like I think we're a little bit in this phase of just trying to survive. We're not thriving, but it's okay. Like it's also the funnest age and like, it's, you know, it's going to get better. And maybe it's just because I have an eight year old where like, he's so fun to be with. I mean, they're all so fun to be with, but like he's actually self-sufficient and I know it'll get easier in some ways and then bigger kids, bigger problems. But right now I'm just trying to survive.
12:16Michael Bosstick:But then I think that's real though. I mean, I mean, that's, we're just hanging on. I'm not sitting over here lying. I'm surviving. Yeah. I'm surviving. I sprinkle myself, Karen, in strategic ways, but I am surviving. No, but I mean, when we had no kids, we had these beautiful long morning routines with walks and tees and journals and all sorts of stuff. I'm like, I don't have that anymore. I'm just like crashing out of the house. I find hacks where I can. I definitely find hacks, little holes. But it's definitely a lot at this age. We have five, six, three, and I don't even know. Yes, exactly.
12:51Michael Bosstick:No, nine months. We're hanging on by three. I think that's cool. But what adds the other layer is you obviously are also in a relationship trying to take care of yourself. You're running a company. The company is doing very well. You have other people looking to you to solve and make sure that they're in safe hands. It's a lot. It's stressful.
13:09Victoria Thain Gioia:Yeah. There are days. So we've been doing the business for almost six years now. And the beginning problems, it's like all chaos and you're all hands on deck and you're doing all the work. And six years later, running the business, you're also running the team. We have a lot of people and it's different problems and it's different challenges. and sometimes it's a little bit more overwhelming. And so it's like I have like four mouths to feed at home and then I've got like 35 mouths to feed at work and like maintain their happiness and health and sort of what they're doing. And it's definitely been a shift over the last six months of like what I spend most of my time doing, but trying to balance it all.
13:51What do you think about creatine while pregnant? I did it every single day. I'm curious to know your thoughts as someone who sort of deals with it every single day?
14:00Victoria Thain Gioia:I mean, I think it's beneficial during pregnancy. I think you need a lot of these kinds of things more during pregnancy like protein and creatine because you're basically running a marathon and your protein needs increase and sort of maintaining your muscle health and your cognitive health, which is huge on the creatine side, is all really important. So I think that's really important. It's just I think there's some like studies out there that make it feel scary, but it's all about the dosage. And I think that's a lot of in the supplement category of like. More is not more. And so you just need to make sure you're taking like the safe and effective dose during pregnancy and just talking to your doctor.
14:45Victoria Thain Gioia:But go talk to your doctor. I did five grams. What do you guys like? We dose at three grams. We have creatine in our protein product. So it's a triple support protein, which is protein plus fiber plus creatine, kind of all the things that women need in this kind of category. And so why make her potion source? Like, let's make it easy for her and put it in one scoop. For women, it is three to five grams. We, because we're founded by an OBGYN, she is very much on the, like, do no harm and what is the, like, baseline you need. And then if someone needs more, they can kind of layer that in for their diet.
15:21Victoria Thain Gioia:it but like again going back to just keeping it as safe and effective as possible are there things
15:27Michael Bosstick:that you guys have identified as a primarily female company that maybe men have been onto or doing for a while that women have not so for example like i've been taking creatine since i was 12 years old right a lot of guys probably say that have you really been taking it since you were 12 like you were 12 in the kitchen yeah i was i was slamming is that actually a true that feels like a tall tale i was slamming muscle bunion there and the ox babe like i was i don't know about that protein shit i was slamming cytogainer and muscle milk i think you might have been 14 not 12 i was taking amino 12 i was literally 12 i'm gonna ask mom about slamming these things i was wearing a muscle shirt walking around like this in the house but what i guess my point is is what i realized with lauren she started weight training with me years ago now and started taking supplements that i and what i it was like a light bulb moment as a man i was like why did i not talk to her about some of these supplements or some of these workouts or some of these proteins that I was taking or creatine.
16:19Thanks for telling me what you were doing since you were 12.
16:21Michael Bosstick:No, no. And I think a lot of men out there are just like, oh, that's like men take that. And now that more women in our lives are saying, okay, I'm taking creatine or I'm supplementing with protein or I'm taking these other things that you've discovered that maybe men have been getting more of that women should look to more.
16:36Victoria Thain Gioia:Yeah. And I think creatine and protein are perfect examples of that. But I think there's like, you can go back further of all of the research studies were done on men. So then it's kind of leaning towards men and women are not actually small men. So great to have some studies done with women and really seeing what the benefits are for women. So I think that's like, if you really went back, what drives some of that. But then also I feel like there's definitely been a transition for women in the last five years, maybe a little longer, but I think really in the last like five years about muscle health for women and muscle mass and like how important that actually is.
17:18Victoria Thain Gioia:I feel like women have lived in diet culture and kind of salads and less is less and really realizing that women actually start to lose muscle mass at age 30, much faster than men. And it's exasperated by hormonal fluctuations such as perimenopause. Like women have hormonal fluctuations, much more so than men. Lucky us. But we need to actually think about that. And so I think the more that research has come out and more of that conversation, it's realizing that women need these things even maybe more so than men. And there's so many studies behind them. There's so many studies, clinical studies behind creatine, and it has been this like Jimbrough ingredient.
Read the full transcript
18:03Victoria Thain Gioia:And then there's actually recent studies on creatine around cognitive health. Yep.
18:07Michael Bosstick:I slept bad last night. I woke up and slammed five grams of creatine just because I slept bad. Yeah. And then he has to do a performance. He's like, this is how I take creatine. And it's like an inch of water in the cup. And he's like chugging it like it's a shot of tequila. You're so proud of yourself. No, but to your point, there's things that I think the quote unquote gym bros have known about where it's like, I know if I have a terrible night of sleep, one of the first things I'm going to do is have maybe a double dose of creatine, not right at once, but five in the morning, then maybe five after the workout.
18:37Michael Bosstick:And it does have neurological protections and cognitive benefits for doing that, especially if you have a bad night at rest. Yeah.
18:44Victoria Thain Gioia:No, I think it's huge. And I think it's important that it's just becoming part of the conversation for women and women's health and actually how important muscle health is for women in terms of longevity and bone loss and bone density. All of our grandmothers had osteoporosis or similar issues, like we can start preventing that, but we need to start preventing that now and sort of building up our muscle health and our bone density. One thing that I've noticed from creatine, this is so weird, is I noticed that my skin is tighter to the muscle. So a lot of people are like, oh, it makes you bloated.
19:22I've found that creatine like gives you that very youthful tightness of the skin around the muscle. And I don't even know how to describe what I'm trying to say. If someone's listening, DM me what I'm trying to say. But it's like, it's almost like the muscles more toned and the skin connects to the muscle more. Like firmness in the skin? I don't, it's like, it's a look. You know how Kim Kelly looks? It's like Kim Kelly.
19:46Michael Bosstick:A lot of women, and again, I don't want to paint every woman, but the women in my life would say, I don't want to take creatine and protein and weight lift because I'm going to get too buff and jacked. Not me. And I always laugh at these women because I'm like, do you know how hard we're trying as men to just get a little bit of muscle? It's like this idea that you're going to take a little creatine and it just doesn't work. But what happens when you do take some of these supplements is, yeah, you'll be able to get more hydration to the muscle. You'll be able to build it in a more effective way.
20:15Michael Bosstick:You'll be able to retain it longer. And so you're going to have that look. When you work directly with your incredible OBGYN, what have you learned from her when it comes to supplements?
20:26Victoria Thain Gioia:Everything. thing. I mean, she has such an amazing approach and she is a medical doctor. She's an OBGYN. She's delivered many of my children, but she has such a holistic lean to her practice, but she really focuses on like efficacy, safety, research, and like what she sees with her patients. So there's been ingredients that are really popular out there and she is like an absolute no. She's like, we cannot include that in our products.
20:54Michael Bosstick:What are those ingredients? You know we're going to ask.
20:57Victoria Thain Gioia:Certain things just can have like liver toxicity. So there's some around like some PMS ingredients, even some like menopause ingredients. And so she's like, those are a no, we're not including those in our products. She's really cautious about the dosage. Like we are creating products that women can take every day. And so what is safe and effective? And like there's a lot of clinical studies at certain dosages. So we can use that to know that it will still be effective, but it's safe for a woman to take every day. And then I think the other part that I really learned from her and her philosophy is just that like supplements are just that.
21:35Victoria Thain Gioia:They're supplements to a healthy diet. And so we need to think of them that way, but it needs to be part of your daily routine. Like how does it fit in? And I think that's also been like the biggest learning as we've made products and formulated. She's all about like tolerability. How does it fit in the use case? I think that went into our formulation with our protein. We were talking about protein. We were talking about fiber. We were talking about creatine. And she's like, this woman needs all of those. Let's make this easy for her. How do we make this something she can take every day? How does this fit in her routine?
22:07And because she's like,
22:08Victoria Thain Gioia:that's the only way this woman's going to take it every day. And she's seen patients for 25 years. And she's like, the biggest issue is making sure someone sticks to this routine. And whether it's like a new diet or a supplement and all of those things. Like how does it fit into their routine? So that's been like, I think a big insight where it's like as a woman or you'll just be like, oh, well, they'll just change the routine and they'll add that to this and then they'll make a smoothie every day. And she's like, well, that doesn't always work. How does this fit into their routine? And she's really pushed us on that side, which has been really helpful.
22:45Knowing everything that you know now, because obviously you've been around the right people and done your research. If you got pregnant today, what would you do?
22:54Victoria Thain Gioia:Yeah, I would be really focused on my nutrition ahead of pregnancy. And I think that's the biggest difference that I didn't realize with my first and going into a pregnancy, how important it actually was to be on the right prenatals, taking the right supplements, you know thinking about egg health like all of that and it's not immediate it's not like especially for egg health it's like three months in advance at the very very least if not like six months to a year so that is something that i've learned through this journey of like really preparing your body for a pregnancy and then like we've done a clinical study on our conception support pack and shown that taking that for at least three months, like increases key nutrients that are critical for a healthy pregnancy.
23:43Victoria Thain Gioia:And so preparing in advance, I think is the biggest piece that I would focus on. And what about when you actually are pregnant? So I think a prenatal is sort of non-negotiable and taking those ingredients, I would take parallel and have sort of the focus on because your needs change between different trimesters. And so that's why I think how we built out our system of you get something that's specific to first trimester, second trimester, third and postpartum. That's fascinating. I think that's so smart. Yeah. I mean, look, you could take everything all at once and take 10 pills a day, but that would be really hard to tolerate.
24:21Victoria Thain Gioia:So like, let's actually be really specific of what exactly you need when and what you don't need at different stages. So I would take that. But I think more so I would also be really focused on my nutrition. I actually think that protein, I probably wasn't very good about that when I was pregnant, at least with my first two. The second two were during parallel. So they're the strongest, most well-adjusted of the bunch.
24:44Michael Bosstick:You're going to hear that in the future and be like, you hear that? They're the stronger ones.
24:47Victoria Thain Gioia:They are. They're well-adjusted. I feel like you're less nervous at the last kids and they're like, figure it out. I tell my siblings because I'm the oldest, I say what happens, I said mom
24:56Michael Bosstick:and dad were the youngest and healthiest. And then so they had me. And then as you guys came along, their bodies were deteriorating. And so you got the weaker stuff. That's the narrative.
25:04Victoria Thain Gioia:Yeah. I like that. But I actually think prenatal nutrition and like your protein needs are so much more important when you're pregnant and women don't realize that at all. And like you can't tolerate food and you have aversions. Like I hated chicken. And so I feel like I ate no protein. And that actually probably would have like, yes, probably benefited the baby, but more benefited how I felt and how I recovered and how like I felt postpartum like the whole process I feel like could have been just felt easier I'd have more energy and like balance my blood sugar better that's like the first one I feel like too I just you don't know what you don't know and it's
25:42Michael Bosstick:the postpartum hits you so bad have you heard people talk about a lack of folate as it relates to postpartum?
25:51Victoria Thain Gioia:I haven't heard that as much as in the postpartum period. I feel like you think more of like iron depletion and energy and like all of what you go through. And then you're just kind of like on the other side of it and everyone cares about the baby. So I think it's more like general depletion than folate. Everyone is throwing around this word clean. What does that actually mean in the supplement and protein world? Well, it means nothing. It's not a regulated word. So I think everyone actually, and it's like sort of the same in beauty, like it actually means nothing. So we have to double click of like, what does it mean to be clean?
26:30Victoria Thain Gioia:And it's something that really needs to be looked at in the supplement industry because it's not regulated in that way. So supplements are not regulated for sort of efficacy and safety. And so it's on, the onus is on brands or the products to actually test and kind of measure what's in their products in terms of heavy metals, contaminants, solvents, any of those things that you don't want in your products. So there's different layers of this that's gone on since we've been in the industry over the last seven years. And most of it's been good because it's kind of pushing. Consumers have become more aware of this.
27:12Victoria Thain Gioia:So they're pushing brands to do the right thing. So one of the things that we did from day one was what's called third-party testing. And that means that every finished lot, well, actually it doesn't mean that every finished lot, but for us, it means that every finished lot, so every time we make the product, even if you make it four times in the year, every time that comes, that is done, we send it to an external lab who third-party tests it to make sure that it has one, like what we say is in it, isn't it? So they test for like the dosages and sort of the potency of the product. And then they test for contaminants and that's microbials and solvents and heavy metals.
27:53Victoria Thain Gioia:And the heavy metal thing is also this interesting conversation in this category. Everything that comes from the ground has trace levels of heavy metals. It's unavoidable. So So if a supplement says they're free from heavy metals, it may be true, but it probably means that they don't have critical ingredients, especially in a prenatal. Like they probably don't have magnesium or zinc or iron. Those are important ingredients. They are going to have trace levels of heavy metals, but it's what is that level? So you third-party test to make sure that those are below USP standards or in our case, we make sure they're below Prop 65 standards.
28:33Victoria Thain Gioia:It's a California regulation and it has really strict standards for what can actually be sold in a product. But you can actually go above that. You just have to you'll see like a Prop 65 warning on the box. And then the like next step of this to actually verify clean is third party certifications. So that's things like the clean label project, which tests all different products independently for the same sort of things of contaminants. Well, first they test for potency to make sure that what's on the label is in the product. And then they test for contaminants, solvents, pesticides, and heavy metals.
29:11Victoria Thain Gioia:And then you can be clean label certified and you can receive a purity award, which means you have the lowest of a lot of those levels. And there's another certification, which is NSF certification, which is sort of the same thing and does the same thing and has their own set of standards. So we've done both of those to really kind of show to the consumer our commitment to, quote unquote, clean. But there are certifications that can set that standard. But in general, anyone could say clean because it's not actually regulated. Wild. So the third party testing is important when you're getting a supplement, it sounds like.
29:49Victoria Thain Gioia:Yes, very. You want to make sure any product you buy, they are third party testing. every single lot, not just saying they do it once a year, every time they make the product. They should be third-party testing and verifying what's in it and any contaminants. With all you guys' research, what have you found when it comes to postpartum anxiety and depression? Are there different things about it? Is it all the same? Is it under one category? I mean, we haven't done a ton of independent research on that. We are working on things on our mom multi-pack and sort of doing some clinical research of how it affects that and what are sort of the precursors to postpartum depression and anxiety like sleep deprivation and energy and like how can we help sort of minimize the precursors to that but we haven't done a ton of research on that I can only say from my own personal experience I had like really severe postpartum anxiety and I feel like those are very different, but they're grouped sort of the same right now and not, I mean, I just think there's so much more to that conversation that can be pulled forward and like people talking about that.
31:00Victoria Thain Gioia:Because I think so many women suffer from both postpartum depression and anxiety, but they're all kind of grouped as the same and not really talked about separately. It totally should be different buckets because I remember feeling depressed, but then at the same time I had such bad intrusive thoughts, thoughts were coming into my mind that I'm like, where did this come from? Like, it's not like I watched a movie about it. Like, it's not like I was like you, you're like all the knives are going to fall out onto the baby and stab the baby. And you're like, what, where did this come from? It's like very, very weird when you're doing stuff with the baby, you think is the baby going to slip out of my hands and like crack his head open.
31:38Michael Bosstick:I think everyone has these thoughts when you're walking and it's like, oh, I could like knock that over or I could like, you know, hurt myself. But you like obviously to catch yourself real quick and don't do but then it's with we should do a meme when a man tries to relate to postpartum i'm just wondering what's going on here yeah i don't think you can really understand but is it just like that like but if you'd like to explain childbirth yeah next let me tell you how much yeah yeah childbirth is like well what they do is they put you on these
32:03Victoria Thain Gioia:really uncomfortable couches oh my god and then i've heard about this so many times and then the
32:08Michael Bosstick:the woman yells at you for being uncomfortable on the couch it's really inconsiderate if i had If you have another baby, I might just do a home birth and make you take a trip. And then you try to get Postmates to find the room you're in. It's a really tough thing that men have to go through. And you had to carry my placenta downstairs. God forbid that thing is eight pounds. Yeah. Well, you know, my back was thrown out. And Lauren was just really not being considerate about it. Honestly, each time you've gotten less considerate towards me. The differences are different feelings. The depression is you feel this for me, you feel almost a little hopeless.
32:48Maybe you feel like there's for me, I felt like there was like a like if I had a windshield, the windshield needed to be wiped. Like it felt like I couldn't see and I was dissociated and I was anything was overwhelming. And then the anxiety feels for me like intrusive thoughts. And it's funny. I've had intrusive thoughts with all three babies but it's gotten less each time like by a huge amount but i i mean i have never spoken to a mom that didn't have a couple of intrusive thoughts after and i could be wrong but it's almost like by the third i was like okay lauren like you're just this is what's going to happen and just be prepared yeah you kind of just like go through it and jokes aside
33:30Michael Bosstick:and with the for our first child and we've talked about it on the show she had postpartum anxiety and depression and I had no clue what to do. I didn't know I had it though either. You don't know you have it. You just, I didn't know. Yeah. And I think a lot of partners in the, like I remember for me and not, it wasn't about me, but I, I hadn't, I just had no idea what was going on. I had no idea how to support it. I didn't even know it was a thing. I think a lot of guys aren't aware about the thing. And all of a sudden one day you're with your significant other and then there's like, they're different, they change.
34:01Michael Bosstick:And now I know. So I, there's things that I could do to potentially help work through that situation. But back then I was like, snap out of it. I've gotten beat up plenty of times since then. But I didn't. My favorite is what's wrong with you? Well, I didn't know. What's fucking wrong with you? So for the guys listening with your girls, if they're pregnant or if they're like, just know that this, don't say what's wrong with you. Just don't speak. Don't ask what's wrong with them. Just sit there and be quiet. He would breathe and I would be like, do you have to breathe like that?
34:30Victoria Thain Gioia:Yeah, I had all these same conversations. Actually, with our fourth, I had really bad anxiety in our first trimester because I'd had quite a few pregnancy losses between babies. And so for this last one, I was also doing like shots of blood thinners and it was just complicated. And I feel like it felt so much pressure. And I started having like panic attacks, which like during the first trimester was so like I didn't know what was wrong with me. and I went down like such a deep spiral before realizing that I was having like a severe like postpartum anxiety spiral while pregnant. And that's also a thing.
35:07Victoria Thain Gioia:And then like found out that that's really common that people don't talk about either. It's funny that you say this because one of my friends is pregnant right now and she called me and she's like a month in. And I said, sometimes when you get pregnant, you almost feel you're so happy that you're pregnant. Like, of course, like you're out of your mind. But there's also a little bit for me of depression that I felt a little bit in the beginning. And I don't know if it's that it's because you know that it takes a lot of work and commitment to carry a child. And there's so many ebbs and flows that you're kind of like, oh my gosh, this is going to be a lot.
35:44But sometimes you're, and I don't know if it's your hormones, but you do sometimes feel a little up and down.
35:50Victoria Thain Gioia:Yeah. Well, your hormones are going crazy. Yeah. And so like, we don't really talk about that. Like that actually affects your mood and what's wrong with you. Like your hormones are on a roller coaster.
36:02Michael Bosstick:You're going to just beat me up. I've been beaten up for this for years. I'm just going to get it again. You can, you can simultaneously feel really grateful and excited, but also like a little blue blue is the word I would use. Depressed is not it. It's not like I felt fully depressed. You just feel blue or like overwhelmed yeah a little bit yeah and i think that that i mean sometimes it happens during your period too yeah women are you know we ebb and we flow and you have to give us space to do that because we're not a straight arrow that's boring like you guys i'm just kidding
36:36Victoria Thain Gioia:it's a joke it's a joke we are hormonal we're hormonal like that's all parts of it sorry we're fun.
36:43Michael Bosstick:No, it's, I mean, listen, it's, it's, you're building a human, right? You're taking basically almost a year to do it. It's pretty intense if you think about it. Now that I've experienced it a few times with her, I'm like, well, like it's pretty wild. And then after that, they're just there and you're just expected to like get on it. Right. Yeah. It's like just bounce back. Yeah. And here, and now it needs to eat and it needs to wake up and like, yeah, it's a lot. It's a lot. It does help that my husband's a good partner. I always tell you this. in there one time in the episode. He is a really good part.
37:12He really helps a lot. And I know that that's not normal. Put that at the front of the episode, Carson. You do help a lot. He helps. Well, I wouldn't have it any other way. I got to be honest. If you didn't help, I'd be like, what in the fuck are you here for? Call the sperm bank because if you're not going to help, I don't know. I'm out.
37:29Michael Bosstick:No, I try to be helpful. He is helpful. Okay. So if someone is listening and they have M-T-H-E-R-F-R. What are the things that they need to do? Is it as simple as really just changing their vitamin? Yeah, just take a methylated folate.
37:47Victoria Thain Gioia:I mean, everyone should just take methylated vitamin. It's not just folate. Like take all the methylated formats, take the chelated formats, like take the things that are most bioavailable to you. I feel like just in general, it's good. But that's it. There's nothing else that you've seen that makes a difference with it. I mean, transparently, I probably haven't done a, I kind of went down this rabbit hole and then spiraled and decided to start parallel and spent more of my time on that. But I think we just focus on what is the most bioavailable format of ingredients and go from there. You do probably not want to take too much folic acid because your body's not really going to process it properly and then sort of remove it as properly.
38:26Victoria Thain Gioia:But I just think in general, take like the most bioavailable format of every ingredient.
38:30Michael Bosstick:Yeah, the way Gary Brekka explained it is if you're pulling raw oil out of the ground, you can't just put it in your car. You need to refine it and then turn it into gasoline and put it in your car so it works. Well, that's over my head. So what we're doing if you have that MTHFRG mutation is you're taking the raw materials that your body can't turn into gasoline and you're putting it in your body and it just literally doesn't work. So if you could just take the form like you're saying right off the bat, you're giving your body what it needs right away without having to turn it into a refinery.
38:56You guys also sent me the cellular hydration thing that I loved. and I took it on like a bunch of my vacations. What is that?
39:04Victoria Thain Gioia:It's our electrolytes. So this is everything that we do at Parallel is we don't do sort of single ingredient products. We really think about what does this woman need out of this? So we were asked a ton of like, what electrolytes should I take, especially during pregnancy? And we brought it to Dr. Iotti and she was like, well, like I'm not just going to suggest electrolytes. One, it is great electrolytes and it's great for hydration. It doesn't have crazy amounts of sodium. So it's safe to take every day, especially during pregnancy. You don't want to overdose yourself on sodium. It tastes so good too.
39:34Victoria Thain Gioia:But it tastes amazing. And then it has collagen in it as well. So it's added cellular hydration boosts or sort of that beauty from the inside out and hyaluronic acid. Yes. That was the thing I liked. Some really good skin boosts. And so we love that flavor. And then we're going to kind of explore how else we can make that fun this summer. If our audience could start with one product from you guys, I know they listened to the episode with alex your co-founder, but what would you recommend they start with? What's your favorite product? So I live by the mom multi-pack I guess maybe I should have answered that of what's my only thing of self-care is I take my vitamins every single night Because I think that they help me from getting sick But I think for general all women and women who might not be in like the pregnancy postpartum season of their lives Not that i'm actually in that is protein I think that we forget how important protein is as women and we typically under eat protein.
40:29Victoria Thain Gioia:You need a gram of protein for every pound of body fat. And that's really hard to get out of a diet. And I feel like we created a protein that has your protein and your fiber where fiber is also critical to your health. And I feel like no one talks about that either because it involves poop and digestion. But like...
40:47Michael Bosstick:People are talking about it more now. It's becoming popular. Thankfully. People are realizing, yeah.
40:50Victoria Thain Gioia:And there's like the gut brain. Like fiber is so important. So it's giving you all of that and it gives you your creatine and it's all in one scoop. So it's like so easy to add that to your daily routine and you kind of check the box on all three. Before you go, you have to tell us you guys are backed by Unilever Ventures. How was also a couple of different growth partners? What is that like from a business perspective? Total off tangent question. Yeah, it's great. We have really great partners. So and I don't think that's always true. We have an all-female board. They're mostly all moms. So they really understand what we're doing.
41:29Victoria Thain Gioia:And I feel like that's made all the difference in having them as partners. And it's actually been great. I would say the fundraising path to getting there was not so great. But we're really, really fortunate to have some great partners now. The fundraising part is a bitch. Yeah. That was unfortunate. Like post-prepartum. we did it also in like april of 2020 when we just had this idea and so there was no fundraising it
41:55Michael Bosstick:was covid the market's been it was like basically bad for like a five-year stretch yeah well while we launched the business so we probably made you better business people though and you know what
42:04Victoria Thain Gioia:it did and every dollar had to count and we raised like not even a quarter of what we planned to to get this off the ground but we weren't willing to cut any of the products because it was like conception each trimester and postpartum. And we're like, well, we can't, that's the whole thing. You can't cut any of that. That's what this woman goes through. So we had to get like really creative in everything that we did. And I do think it made us better on the other side, even though it didn't feel that way in the moment.
42:35Michael Bosstick:Well, I just think a lot of people that were in the more flush times, it was like, here's a shitload of money and then just grow to grow. Don't worry about being efficient. And when the market got tough, it's like, hey, we can't back this anymore. It left a lot of people high and dry. Which if you really think about it, it's like it never made sense to just build a super unprofitable, highly scaled business that you couldn't sustain without just injecting more and more and more cash into it.
43:01Victoria Thain Gioia:It didn't make any sense. We're not software businesses. We're selling products. So you have to make sure you have a sustainable business model. You want to be here for the long term. If you're going to get people hooked on products, you need to continue to be able to sell them.
43:13Michael Bosstick:Yeah. And then I just think like, you know, not enough founders talk about it. It sounds like you have great partners, but you got to be careful with some of these people on the financing side because they get your hooks in a way where like there's so many horror stories of founders taking terrible terms, raising too much money, like selling their company, ending up with nothing. It's just, it's, it's a mess. Might as well just slow and steady wins the race.
43:35Victoria Thain Gioia:Yes. I have a finance background and that's how I started my career. So I was very fortunate to know what not to take in terms of those terms. And even though some things I feel like we got a little desperate and had to take some things, but I don't know founders that don't have that background. It's really tricky.
43:55Michael Bosstick:It's hard. Where can everyone shop Parallel? You guys, go try that hyaluronic acid collagen concoction. You will love it. And where can everyone pick up all the goods?
44:05Victoria Thain Gioia:At parallelhealth.com. It's P-E-R-E-L-E-L health.com. And check us out. You guys can use code skinny at parallelhealth.com slash skinny. You get 20 % off your order. Thank you so much for coming on. That was amazing. And tell Alex that we say hi. Of course. Thank you. You killed it.
From the publisher
#956: Join us as we sit down with Victoria Thain Gioia – the Co-Founder and CEO of Perelel, the first OB/GYN-founded vitamin company redefining pre- and postnatal health. Victoria is on a mission to give women access to doctor-formulated, research-backed supplements that are tailored to every stage of their hormonal journey. In this episode, Victoria gets candid about the importance of third-party testing for safety, the benefits of creatine for women, opens up about postpartum struggles, shares practical supplement routines for every stage of life, and optimizing female muscle health amidst hormonal fluctuations. She also breaks down the importance of methylated folate over folic acid, especially for those with the MTHFR gene mutation, and shares actionable tips women can implement immediately for better health and vitality.
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