In short
A two-part Scientific American “Impossible Questions” series episode on what happened before the Big Bang, framed through why some scientific questions remain unanswered. It proposes four categories: (1) need more research (e.g., how acetaminophen works; aliens exist but lack evidence), (2) questions we could answer but may not want to (ethical limits, especially drug safety in pregnancy), (3) questions we couldn’t ask until new tools/ideas existed (microscopes → microbes → microbiome → mental health; Greenland shark and “Ming” clam aging methods), and (4) seemingly insurmountable barriers (life’s origin; “before” the Big Bang).
Key claims
“before” may be meaningless because Big Bang may mark the start of time; theories include no-boundary proposal, big bounce, and a mirror universe, but none can be definitively tested.
Notable examples
Greenland shark protein carbon-dating (272-year average); Ming clam shell-layer dating (born 1499).
Guests
Sarah Skulls, senior contributor at Scientific American; author of the “What happened before the Big Bang?” piece.
Written by AI. May contain mistakes. Listen to the episode to check what was said.
Chapters
Tap a time to open that second in VOExploring the Impossible Questions Issue
0:36 to 1:07
Discussion on the new issue of Scientific American focusing on unanswered scientific questions.
“You can save on select appliances designed to make laundry day easier.”
Exploring the Impossible Questions Issue
1:30 to 2:56
Discussion on the new issue of Scientific American focusing on unanswered scientific questions.
“And when I found out about it, it was like someone put the bat signal up in the sky.”
Taxonomy of Unanswered Questions
2:56 to 6:09
The hosts categorize unanswered questions in science and discuss examples.
“but we don't always zoom out and talk about why they're all unanswered.”
The Start of Life and the Big Questions
6:09 to 11:03
The conversation shifts to big, philosophical questions like the origin of life and what happened before the Big Bang.
“Okay, so that is actually a perfect segue into my next bucket.”
Theories Before the Big Bang
11:03 to 13:52
Discussion about what could have happened before the Big Bang and introduction to upcoming theories.
“Okay, the last bucket might be the biggest bucket.”
Theories Before the Big Bang
14:42 to 15:00
Discussion about what could have happened before the Big Bang and introduction to upcoming theories.
“You think you know a browser, but Gemini and Chrome, that's new.”
Exploring the Big Bang's Precedents
15:22 to 16:18
Sarah discusses her journey into questioning what came before the Big Bang.
“So you wrote this great piece for the Scientific American Impossible Questions series, and it's all about what happened before the Big Bang.”
The No Boundary Proposal
16:18 to 17:47
Understand Stephen Hawking's no boundary proposal regarding the universe.
“Oh my God, this is such a great entrance into this question.”
The Concept of the Big Bounce
17:47 to 19:53
Learn about the big bounce theory as a cyclic model of the universe.
“So in the 80s, Stephen Hawking and another physicist named James Hardell were like, this doesn't make sense.”
The Mirror Universe Theory
19:53 to 22:19
Discover the idea of a mirror universe where time flows backward.
“But there's just stuff that's been in there the whole time?”
Show all 12 chapters
The Challenge of Cosmic Questions
22:19 to 24:15
Delve into the unanswerable nature of questions about the universe's origins.
“But the idea here is that everything in the mirror universe is flipped.”
The Awe of the Unknown
24:15 to 25:11
Sarah reflects on the excitement of the unknown in cosmic exploration.
“Or, you know, I think we're stuck in our own reality that really has very little to do, perhaps, with the fundamental laws of the the universe and I don't know if our puny brains can figure that out.”
Transcript
Automatic transcript. May contain errors.0:00Rachel Feltman:Support for the show comes from Google Gemini. You know that moment when curiosity strikes? You're exploring a new city with a family and a sculpture catches your daughter's eye. What is that? Who made it? With Gemini, you can snap a picture and get a fully interactive breakdown of its history, architecture, and even hidden secrets. Gemini is built for moments like that. Whether you're learning something new, solving a problem, or looking for your next favorite thing, Google Gemini is here to help. Download Gemini, Google's AI app, or visit gemini.google.com to learn more.
0:58Sarah Scoles:Great prices at The Home Depot. You can save on select appliances designed to make laundry day easier. Shop Labor Day savings at The Home Depot today. Offer valid August 27th through September 16th. USNAC store online for details.
1:21Sarah Scoles:Rachel Feltman. Hi. Welcome to the show. Thank you. So you host Scientific American's podcast, Science Quickly.
1:29Rachel Feltman:Yeah.
1:29Sarah Scoles:And I wanted to talk to you because Scientific American has this special issue out called Impossible Questions. It's out in print. It's out online as of yesterday. And when I found out about it, it was like someone put the bat signal up in the sky. Like someone somewhere is talking about what scientists don't know. And I wanted to talk to you all about it. But before we get into it for anyone who isn't familiar with Scientific American. Can you just set the stage a little bit?
2:02Rachel Feltman:Yeah. So Scientific American is the oldest continuously published magazine in the United States.
2:08Sarah Scoles:Okay.
2:08Rachel Feltman:Yeah. Yeah. We're old, but we've got a lot of life left in us.
2:12Sarah Scoles:The magazine
2:13Rachel Feltman:was founded in 1845. Wow. Yeah. Okay. We have a lot of people say, you know, like, my grandfather had a subscription to Scientific American, and then my dad did, and now I do, and we love it.
2:28Sarah Scoles:Yeah, one of the last people I interviewed for the show, Hank Green, I was asking him how he got into science in the first place. And the first thing he said was, when I was a kid, my parents got me a subscription to Scientific American.
2:40Rachel Feltman:Yeah, we love to hear that.
2:42Sarah Scoles:All right. So we're planning to do two episodes on this Scientific American issue. We're doing one today, one on Monday. And I wanted to kick it off with something we haven't really done too much on our show. Because we talk about unanswered questions all the time, but we don't always zoom out and talk about why they're all unanswered. And the impossible questions issue, it inspired me to make a sort of, I don't know, taxonomy of unanswered questions. It's definitely not exhaustive. I'm sure some questions aren't going to fit in perfectly here. But I came up with four big categories that helped me wrap my head around why questions are unanswered.
3:27Sarah Scoles:So I figured I could run them by you.
3:30Rachel Feltman:Yeah.
3:30Sarah Scoles:That sound good?
3:31Rachel Feltman:That sounds great.
3:33Sarah Scoles:Okay, so the first kind of bucket I came up with is really the clearest, which are the questions that we're trying to answer but just need more research. Like, the research is hard and we're doing it and we're not there yet. So we still kind of fundamentally don't know exactly why things smell a certain way.
3:53Rachel Feltman:Yeah.
3:53Sarah Scoles:And, you know, I think about a question we talk about a lot, which is like, do aliens exist? And like, we're working on it. Like, we're looking and we just need more time.
4:05Rachel Feltman:Yeah, you know, I love that bucket because I think a lot of people sort of assume all of the questions that scientists would bother working on are in that bucket, which of course is not the case. But one that comes to mind is how acetaminophen works.
4:24Sarah Scoles:Yeah.
4:24Rachel Feltman:So Tylenol is a big one, but then in a very different category of a very common drug, like most, if not all antidepressants.
4:34Sarah Scoles:Yeah.
4:35Rachel Feltman:There is this thing where there are drugs that we know work well enough. We use them quite often. They provide immense benefit to many people, but we don't actually know definitively what the mechanism is by which they are working. which is pretty mind-blowing and does seem like a question that surely must be answerable if we just get more information.
5:06Sarah Scoles:Intuitively, you might think, okay, unanswered questions are unanswered because they're so big or they're so far away. And even things that we're so physically close to are still hard to answer. Like, it's not just, is there an alien out there? Or is there, you know, a mysterious planet in the furthest reaches of our solar system? It's like, what's up with our nose?
5:29Rachel Feltman:Totally. Yeah. And not to, like, climb on my soapbox too much, but, you know, a big category of those unanswered questions are ones that, you know, mainstream science has simply not dedicated resources to. So reproductive health and endometriosis, things that are very present, very close. And we have this big knowledge gap, which thankfully we are starting to see get resolved. But yeah, I think there are so many questions like that where it probably isn't that the question is so insurmountable, but someone does have to put the resources toward trying to answer it, which has not always been the case.
6:11Sarah Scoles:Okay, so that is actually a perfect segue into my next bucket.
6:14Rachel Feltman:Oh, good.
6:14Sarah Scoles:In a slightly different way, but the next category I was thinking of, which is easy to miss sometimes, is questions that we really could be answering, but we might not want to. And there might actually be a good reason why we wouldn't want to. Like, these are sort of moral, ethical, should questions where the best way to answer it would be to test some dangerous substance on people or to withhold something from them. But one thing that occurs to me in this realm, and this is why I bring this up after the endometriosis thing, is I think a lot about the fact that we know so little about what medications are actually safe for people who are pregnant.
6:58Rachel Feltman:Absolutely, yes.
7:00Sarah Scoles:And it might be hard to design an experiment for that because it would be very difficult to say, hey, you're pregnant. Take this pill. We don't know how it's going to react.
7:10Rachel Feltman:Yeah. No, this is something that I've been thinking about a lot lately because I had my first kid not long ago. And it's such a problem, but one that, like you said, there isn't a great solution for, at least in the current paradigm, for like our best way of studying drugs.
7:27Sarah Scoles:Yeah, and drug companies got scared off of testing stuff on people, like people who might just even have a remote possibility of being pregnant. Sure, yeah. And what we've ended up with is a world where we actually just don't know a lot of impact of medication in general on women.
7:45Rachel Feltman:Yeah, no, I definitely think that's true. And it's so thorny to even talk about. You know, on the one hand, I think anybody with any kind of moral compass can see that the way that a lot of science was conducted in the 19th and a lot of the 20th century was not good in that respect, that, you know, a lot of unethical decisions were made. But, you know, I think it's good that that scared us, but we aren't great at figuring out the nuance there.
8:20Sarah Scoles:And it just it leads to this place where it's like we're somehow OK with the fact that we just don't know how so many of these drugs work on women.
8:30Rachel Feltman:Yeah, exactly. It's very strange. It is very strange.
8:33Sarah Scoles:So the next group of questions I've been thinking about is the questions we didn't know were unanswered because we didn't even know we could ask them. Yeah. Like we didn't have the tech or we didn't have the observation or we didn't have the right theory to even get to a place where we could ask that question. So, you know, an example I think of is how microscopes let us ask questions about microbes. and then that let us ask questions about the microbiome. And then we get to a place where we can ask questions about the impact of the microbiome on our mental health. You know, a couple hundred years ago, you couldn't sit around and be like, what is the impact of all the little bacteria in our gut on our mental health?
9:20Sarah Scoles:Like that wouldn't mean anything.
9:22Rachel Feltman:Yeah. You know, one that I think works well for this bucket is the question of what the longest lived animal is.
Read the full transcript
9:31Sarah Scoles:Is this the Greenland shark?
9:34Rachel Feltman:So yeah, for listeners who don't know, I think it was 2016, researchers looked at proteins from the eye lens of a bunch of Greenland sharks.
9:44Sarah Scoles:Almost like an organic living carbon footprint in the back of their eye and do an organic version of carbon dating like we would do with some ancient artifact.
9:55Rachel Feltman:Then they found an average lifespan of 272 years. The largest shark that they looked at was 392 years old, plus or minus another like 100 or so years.
10:07Sarah Scoles:It's like a shark that like overlapped with Shakespeare or something.
10:10Rachel Feltman:Yeah, yeah. And so that's the longest lived vertebrate. The oldest invertebrate is a clam nicknamed Ming because she was born in 1499 during the Ming dynasty.
10:22Sarah Scoles:Clam shells are deposited in layers like tree rings. So if you count the layers, you can figure out how old the clam is. And they didn't discover Ming's age until they returned to the lab and examined its shell under a microscope.
10:34Rachel Feltman:It's not that we never would have asked, you know, how old is the oldest thing? But it was just like a philosophical question.
10:42Sarah Scoles:Yeah, we wouldn't have had a way to actually get an answer.
10:44Rachel Feltman:Yeah, except, you know, maybe like looking at historical records that are like, wow, my family has been watching this one clam for centuries and it's cursed with life. So yeah, I like how that one would have absolutely like boggled the mind of a scientist. So that's pretty cool.
11:03Sarah Scoles:Okay, the last bucket might be the biggest bucket. And this is more of the classic, big, unanswered questions that people might think of when you say, oh, what are the biggest unanswered questions in science? The way I'm thinking about this bucket is like, there's some insurmountable barrier or at least seemingly insurmountable barrier between us and the answer. Like, how did life start? Or what happened before the Big Bang? Something that seems like we could never get past.
11:36Rachel Feltman:Yeah, there are so many questions like this. And there are several, in fact, in this print issue of Scientific American. These are sometimes the most fun. Yeah, yeah. Well, so what came up for the Big Bang is a really fun one. Because the word before is no longer accurate, actually. because the Big Bang wasn't just the start of space. It was the start of space type. So it was also the start of time. So what does it mean for something to have happened before the Big Bang?
12:08Sarah Scoles:At the same time, though, you never know what kind of new tech or new theory is going to come around and give us a way in, like with the microscope and the microbiome. And I don't know, sometimes just kind of wrestling with these questions. I feel like it could take us to some pretty fun places. So I actually want to try that with the Big Bang question. Even though it seems totally impossible, there are some very interesting theories of what could have happened before the Big Bang. And we're going to get into it... after the break.
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15:12Sarah Scoles:Why don't we just start with who you are and what you do?
15:17Rachel Feltman:My name is Sarah Skulls, and I am a senior contributor at Scientific American. All right.
15:22Sarah Scoles:So you wrote this great piece for the Scientific American Impossible Questions series, and it's all about what happened before the Big Bang. Yeah. How did you even start thinking about this question?
15:34Rachel Feltman:Yeah. I mean, if we go all the way back to when I was a kid, I grew up super religious, but I was always an annoying kid who was like, well, if God created the universe, who created God? and then what came before that. And then when I went to college and became not religious anymore, it turned out I was still interested in the same questions.
15:54Sarah Scoles:The big impossible questions? Exactly.
15:57Rachel Feltman:Still annoying. And my roommate and I would sit in our room and be like, well, if space is expanding, what is it expanding into? And if the Big Bang was the beginning, what happened before that? And now I'm a science journalist and I thought, you know, there's probably some people thinking about this question professionally and I could just bother them instead of my Sunday school teachers like I used to.
16:18Sarah Scoles:Oh my God, this is such a great entrance into this question. I guess, how is it even possible that someone could try to answer a question like this? Isn't it by definition impossible?
16:31Rachel Feltman:Yeah, I think, I mean, it depends on how you think about it. The Big Bang is definitely a hard boundary. We can't even like see or gather data from the time right after it, let alone see right back to it. And so if you can't even see there, you definitely can't see before there. So I think the way that scientists think about it is maybe there are some imprints left on the universe that we can see that provide some clues for what happened before.
16:59Sarah Scoles:Okay. So what did the scientists you talked to tell you about this question? Did they have theories for what might have happened before the Big Bang?
17:05Rachel Feltman:Yeah. So the first theory is called the no boundary proposal, which is based on this idea that if you look at the modern universe and you say, how did it get like this? You can rewind back and say like, what initial conditions would I have needed to go from the past to the present? And then you can kind of go backwards and backwards and backwards forever, but that doesn't make sense because as far as we know, the Big Bang created time. And so there cannot be a before the Big Bang because there was no time before the Big Bang. So if this isn't making sense, That's how it's supposed to be because this proposal came from the fact that if you do that, it doesn't make sense.
17:47Rachel Feltman:It sounds like gobbledygook. So in the 80s, Stephen Hawking and another physicist named James Hardell were like, this doesn't make sense. So let's try to think about it without the universe having a beginning. Let's let go of time, our concept of time in that way. And let's think of the universe as a four-dimensional space-time sphere. the way that scientists told me to think about it because like that's not something our brains don't encounter four-dimensional space-time spheres not often not often so they said think of it like the globe like if the universe in space and time is a globe then the beginning of the universe the big bang is the the north pole and so asking what happened before the Big Bang is kind of like asking what is north of the North Pole?
18:39Rachel Feltman:Like, nothing.
18:39Sarah Scoles:Oh, interesting. That's almost like a Zen koan or something.
18:43Rachel Feltman:Yes, exactly.
18:45Sarah Scoles:So that's not an answer to the question. That's just sort of like rejecting the question?
18:49Rachel Feltman:Yeah, sort of. Yeah, it's a very fancy way of rejecting the question. Okay.
18:53Sarah Scoles:Are there any ideas of what happened before the Big Bang that are not kind of rejecting it, that are actually taking it seriously?
19:01Rachel Feltman:Yeah, one that I found interesting is this one called the big bounce.
19:06Sarah Scoles:The big bounce?
19:08Rachel Feltman:The big bounce, yeah. So as far as scientists know, as far as we can see right now, you know, the universe is expanding at an accelerating rate. But in this cyclic universe theory, there's the idea that at some point it starts contracting.
19:24Sarah Scoles:And this is not the big crunch?
19:26Rachel Feltman:This is not the big crunch because it doesn't shrink all the way to nothing. and it's not like a violent contraction. It kind of contracts slowly and not all the way down and then starts expanding again. And so the Big Bang would kind of be that transition.
19:43Sarah Scoles:So wait, wait, this is saying that the universe expands and contracts and the moment it switches from contracting to expanding, it looks like what we think of as the Big Bang. Correct. But there's just stuff that's been in there the whole time? There's stuff that's been there forever?
20:02Rachel Feltman:Yeah, that's my understanding. And the scientist I spoke to about it said, you know, there is some stuff from the previous universe that gets carried along into ours.
20:14Sarah Scoles:But I guess, like, it's not a previous universe. It just looks like a previous universe.
20:19Rachel Feltman:Yeah, which I guess is also sort of rejecting the question because then you have to ask, how did all of this get started? what was before the first big expansion and big bounce. So it is also not totally answering the question.
20:32Sarah Scoles:Does this scientist have an answer to that question or?
20:36Rachel Feltman:No, I think that's asking too much. Okay. I mean, it is asking a lot.
20:41Sarah Scoles:But both of those ideas are still kind of saying there's no big fundamental before and after here. Like the first one says there's just no before. Like, it doesn't mean anything. And the second one is kind of saying there's no real big bang, or it's not like as bangy as we thought. Are there any ideas out there that are like, what's before is super different from what happened after? Like, different from what we can see now? Yeah.
21:14Rachel Feltman:So there's this one idea called a sort of mirror universe. The scientist I spoke to said to picture it like two ice cream cones, kind of pointy end to pointy end. Our universe is expanding, making this cone in one direction. Time is going forward. Stuff is made of matter. And then on the other side, in the other ice cream cone, it's going the other way. The universe is running backwards. Time flows backwards. Stuff is made of antimatter instead of matter. And all of the directions are reversed. So it's a literal mirror of what is going on here. And the Big Bang is where those two things are touching.
21:58Sarah Scoles:Or is it flowing? What does it mean for time to flow backwards?
22:04Rachel Feltman:I think this is one of those things, again, where our human brains, because we live in a universe where time does flow forward, and as far as we know, it only flows forward for us, it just doesn't make sense for time to go backwards.
22:19Sarah Scoles:But the idea here is that everything in the mirror universe is flipped. Yes. And then I guess, am I wrong in assuming that this still begs the question of what happened before that?
22:34Rachel Feltman:Like, how did these mirror images of each other get there in the first place? Exactly. Who made the ice cream cones? Yeah, so I think once again, we come back to the fact that the question is perhaps impossible because these are ways of answering it in a way that just calls the question again at a different point in the universe's history. Hmm.
22:54Sarah Scoles:What are the chances that any of these theories is right?
22:59Rachel Feltman:I think even most of the people who have come up with or work on these theories would say the chances are probably not high that any one of them is correct. I think one of them actually said that to me. He said something like, we're just trying to throw spaghetti against the wall and see what sticks and just keep throwing ideas out there for what could make sense based on what we see in the universe today. And in some ways, there's not necessarily definitive ways that we could decide whether any of them was the correct explanation because you can't see before the Big Bang. And so that's frustrating to me and my inner child.
23:38Sarah Scoles:So do you think it is ever going to be possible to get to a final answer on what happened before the Big Bang?
23:44Rachel Feltman:Yeah, I'm wary of saying never in science because you never know what sorts of tools scientists are going to come up with. But to me, sitting here in my chair in 2026, it doesn't seem to me like it's something we could ever find out definitively. I think there's fundamental barriers to data gathering in the universe. And I also think there's probably fundamental barriers to how our brains can think about it. Like, maybe before isn't a concept that the universe abides by. Or, you know, I think we're stuck in our own reality that really has very little to do, perhaps, with the fundamental laws of the the universe and I don't know if our puny brains can figure that out.
24:26Sarah Scoles:Is there something about the fact that this feels unanswerable that is more exciting to you? Like, if you could answer this, would you want to?
24:36Rachel Feltman:Yeah. I mean, I think that I think I would like to have the answer, but it is sort of reassuring to me in a weird way that there are things that, like, are probably beyond us and that we get to wonder about and people get to come up with crazy ideas like the universe is a four dimensional space time football or whatever. And I think it kind of opens up a different version of maybe awe, I guess, like not necessarily religious awe, but just, you know, cosmic awe, like the universe is so strange and we have so little of it figured out. And I do think that's exciting. There's so much out there that we haven't discovered, and then beyond that, there's stuff we probably never will, and I think that's great.
25:25Rachel Feltman:The universe should be able to keep its secrets if it wants to.
25:36Sarah Scoles:This was the first episode of our two-part series with Scientific American. If you want to read more about this and other impossible questions, go check out their special issue. You can find it in print or on their site at scientificamerican.com. You should check out their excellent podcast, Science Quickly, and stay tuned for the second episode next week. This episode was produced by me, Noam Hassenfeld. It was edited by Meredith Hadenot, who runs the show. Fact-checking from Melissa Hirsch. Mixing and sound design by Christian Ayala. Music from me. Our video editor is Jacob Reynolds. Our animator is Kareem Correa.
26:11Sarah Scoles:Our editorial director is Joanna Solitaroff, and Bird Pinkerton slung the guitar strap over her shoulder and headed back into the passageway. She tried to retrace her steps, but before she knew it, she was lost, alone in the darkness.
26:32Sarah Scoles:Special thanks to Clara Moskowitz, and thanks as always to Brian Resnick for co-creating the show with me and Bird. If you have thoughts about the show, we would love to hear from you. You can email us at unexplainable at vox.com. We read all the emails. Or if you'd like to support the show, join Vox. Become a member. Just go to vox.com slash members. And if you signed up because of us, let us know. Unexplainable is part of the Vox Media Podcast Network. And we'll be back next time with the second episode of our series with Scientific American.
27:13Sarah Scoles:Labor Day savings are happening now at the Home Depot with select appliances starting at$399. Plus, save up to an extra$1 ,000 and get free delivery on appliance purchases of$998 or more. Get a Whirlpool laundry tower featuring industry-first UV clean technology designed to reduce bacteria in the wash without fading fabrics. Plus, with great prices at the Home Depot, you can save on select appliances designed to make laundry day easier. Shop Labor Day savings at the Home Depot today. Offer valid August 27th through September 16th. USLAC store online for details.
27:43Rachel Feltman:Push your limits, train with precision, see the results. At Equinox, that's high performance loving. Everything you need to lock in and unlock your potential at Equinox. Start today at equinox.com.
From the publisher
It's a question that seems impossible to grapple with, but scientists won't take no for an answer. In this collaboration with Scientific American, we take on the big bang and a whole bunch of seemingly impossible questions.
Guests: Rachel Feltman, host of the Science Quickly podcast; Sarah Scoles, senior contributor at Scientific American
For show transcripts, go to vox.com/unxtranscriptsFor more, go to vox.com/unexplainableAnd please email us! unexplainable@vox.comWe read every email.Support Unexplainable (and get ad-free episodes) by becoming a Vox Member today: vox.com/membersThank you!
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