Dr. Mark Hyman: The Secret to Aging Backwards and Improving Your Health | Mental Health | YAPClassic

5 Jun 2026 · 54 min · 27 chapters

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In short

Dr. Mark Hyman discusses longevity and “aging backwards” through functional medicine: optimizing sleep, stress, diet, exercise, microbiome, mitochondria, and immune function; reframing health as more than absence of disease; and treating aging as a root-cause process linked to inflammation and “hallmarks of aging.” He explains epigenetics/exposome (environmental exposures shaping gene expression) and claims biological age can move backward with consistent lifestyle changes and targeted supplements.

Guest backgrounds

Dr. Mark Hyman is a functional medicine physician, best-selling author (Young Forever, Food Fix), and co-founder of Function Health. He says he spent ~40 years studying body function and has treated many chronic-disease patients using root-cause approaches.

Key claims

Frailty isn’t normal aging; it’s preventable. Inflammation can connect conditions like depression, migraines, reflux, IBS, prediabetes, and psoriatic arthritis. Epigenetic reprogramming can reverse biological age; he cites “Almanac factors” research and his own biological age results (chronological 62→biological 43; later 64→biological 39). He argues GLP-1s are tools, not panaceas.

Notable examples

A 50-year-old patient with multiple inflammatory conditions improved after a whole-food, low-sugar/low-starch diet plus gut reset (antibiotic/antifungal, probiotics), leading her to stop drugs and resolve symptoms. He also describes blue-zone observations in Sardinia/Icaria and a mouse study where methylating nutrients during pregnancy prevented “yellow fat” offspring phenotypes.

Written by AI. May contain mistakes. Listen to the episode to check what was said.

Chapters

Tap a time to open that second in VO

Peer Learning and Entrepreneurship

0:57 to 2:11

The host shares the importance of learning from peers and invites entrepreneurs to apply for the podcast.

“One of the best ways to learn as an entrepreneur is from your peers.”

Introduction to Dr. Mark Hyman

2:18 to 3:37

The host introduces Dr. Mark Hyman and his mission in the longevity field.

“Again, that's youngandprofiting.com slash apply.”

Defining Health and Aging

3:37 to 5:46

Discussion on health definitions, aging, and the keys to a vibrant life.

“Mark Hyman is a renowned functional medicine physician, best-selling author, and one of the leading voices in the science of longevity.”

Understanding Aging and Health Optimization

5:46 to 8:20

Insights into the science of aging, longevity, and health optimization strategies.

“We're seeing a lot of research, for example, there's a Washington Post article recently about the Almanac factors, which is basically a scientific discovery that won the Nobel Prize.”

Case Study: Inflammation and Health

8:20 to 12:20

Dr. Hyman shares a patient case highlighting the impact of inflammation on health.

“And all the branches and the leaves are all the diseases and all the specialties.”

Function Health and Personalized Medicine

12:20 to 14:01

Discussion on Function Health's platform and the future of personalized medicine.

“sort of, but they didn't really deal with the problem.”

Personalized Medicine and Function Health

14:01 to 16:25

Learn about the shift towards personalized medicine and how Function Health is pioneering this approach.

“and you get 100 of those people, and you put 51 group and a 50-another group, and you give them a drug, and you see what happens at the other side.”

Personalized Medicine and Function Health

16:31 to 18:09

Learn about the shift towards personalized medicine and how Function Health is pioneering this approach.

“Get more with Northwest Registered Agent at northwestregisteredagent.com slash yapfree.”

Personalized Medicine and Function Health

18:13 to 19:21

Learn about the shift towards personalized medicine and how Function Health is pioneering this approach.

“To claim your 15 % off discount and your bonus gift.”

Differentiating Biohacking and Functional Medicine

19:34 to 21:21

Understand the distinction between biohacking and functional medicine from Dr. Hyman’s perspective.

“My first question to you, I mentioned biohacking and you kind of like got like a little offended when I when I when I tried to compare what you were doing with biohacking.”
Show all 27 chapters

Aging as a Disease and Its Treatment

21:21 to 24:06

Explore the concept of treating aging as a disease and the necessary lifestyle factors for optimal health.

“You have tens of thousands of metabolites in your blood and chemicals.”

Understanding Biological and Epigenetic Age

24:06 to 27:48

Learn about biological age, epigenetics, and how lifestyle impacts our health.

“default by these situations that they found themselves born into.”

The Exposome: Influencing Our Health

27:48 to 28:01

Discover the concept of the exposome and how it affects our genetic expression and health.

“So basically the concept that I think is really important called the exposome.”

The Exposome and Its Impact on Health

28:01 to 32:39

Learn about how the exposome influences our biology and health outcomes over time.

“Your epigenetics are going to track as if you're younger.”

Longevity Switches and Autophagy

32:40 to 33:48

Discover the role of longevity switches and the autophagy process in maintaining health.

“On the flip side, is there any time that's like too late to get started on this?”

Mitochondrial Health and Aging

33:49 to 36:16

Understand how mitochondrial function affects aging and overall energy levels.

“of activate these longevity switches and pathways and i talk about that a lot in my book young forever.”

Mitochondrial Health and Aging

37:03 to 38:12

Understand how mitochondrial function affects aging and overall energy levels.

“When you start a business, nobody warns you that you're about to become the creator, the marketer, the finance team, the customer support team, and the person who's chat GBT-ing why checkout is not working.”

Purpose and Longevity in Life

38:17 to 42:00

Explore the importance of having a purpose and making lifestyle changes as we age.

“I want to talk about your drive of wanting to live so long.”

Understanding GLPs and Their Impact

42:00 to 45:20

Explore the role of GLPs in weight management and the underlying issues of food addiction.

“These are great steps to start to push the food system to produce healthier food for all of us.”

Lessons from Our Ancestors

45:20 to 48:42

Learn how ancient diets contributed to longevity and community health.

“And when you think about the past, you might think like people died at like 30, 40.”

The Role of Community in Health

48:42 to 51:31

Discover how social circles influence health and lifestyle choices.

“So if there was one thing that you could remove from the grocery stores, what would it be?”

Practical Health Transformation Tips

51:31 to 55:01

Get actionable advice on diet, exercise, and managing stress for better health.

“I feel like there's a lot of mixed advice when it comes to exercise.”

Opportunities in the Wellness Market

55:01 to 56:00

Understand the potential for entrepreneurs in the health and wellness industry.

“So that was great advice on an individual level.”

Finding Your Passion and Purpose

56:00 to 57:00

Learn how to discover the intersection of your passions and needs to find purpose.

Investing in Your Health for Success

57:00 to 58:00

Understand why health is crucial for achieving personal and professional success.

“It could be like totally different from what we talked about today.”

The Secret to Profiting in Life

58:00 to 59:05

Explore how focusing on what you love can lead to a fulfilling life and unexpected success.

“And your book, Young Forever, really is just like a blueprint for how to do that.”

Where to Find Dr. Mark Hyman

59:05 to 59:34

Discover how to connect with Dr. Hyman and explore his resources.

“So I think when you do that and you have a mission and you're, you're driven, you know, then it's not about the money.”
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Transcript

Automatic transcript. May contain errors.

0:02Hala Taha:Hey, young Improfitters. When I think back to the early days of Yap Media, I was way too scrappy. I'm talking about working out of coffee shops, bouncing between public Wi-Fi networks, and hotspotting from my phone just to get through on a client call without the connection dropping. But looking back, it was actually adding a lot of unnecessary stress because you realize pretty quickly your business is only as strong as your connection. It's how you run meetings, serve clients, and keep everything moving. And that's exactly why I wish I had AT &T Business back then. They're built for small business owners who need their internet to work without second guessing it.

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1:27Hala Taha:how to scale. And we want to hear from you. One of the best ways to learn as an entrepreneur is from your peers. And I found it super helpful to be in these peer entrepreneurship groups and learn from other entrepreneurs who are at my level, but just in a different industry. So that's what I want to bring to this podcast. I want this to be our own peer group, but on the podcast. And so I'm going to be interviewing people who are making anywhere from 500 ,000 to$10 million a year. They're not super famous. They're not the typical billionaires that are on my show. These are real entrepreneurs who are crushing it behind the scenes, and we're going to uncover what they do to sell, how they get their customers, what their profit margin looks like, how they market, and so much more.

2:07Hala Taha:If this sounds like you and you want to be featured on Young and Profiting Podcast for our How We Profit series, just head to youngandprofiting.com slash apply and share your story. Let me know why you think you should be featured on the show. Again, that's youngandprofiting.com slash apply. And who knows, maybe you'll be our next guest on Young and Profiting Podcast. You want to live to be 120 years old. Why do you actually want to live so long?

2:32Dr. Mark Hyman:I love life. What is the definition of health? It's not the absence of disease. It's something else. How do we unlock the keys to optimal biological performance? I spent 40 years studying the science of function of the body. Frailty is not a normal consequence of aging. It's a consequence, a phenomenon that happens as we get older if we don't do something about it. We have dysregulated sleep schedules. We have tremendous amounts of stress. We eat crappy food. We don't exercise enough. There's all these things that we're doing to impede our ability to actually live a vibrant, long, healthy life.

3:02Hala Taha:What did you do to reverse your age 20 years?

3:05Dr. Mark Hyman:I have been eating.

3:07Hala Taha:Let's say you gave you a 35-year-old. They're stressed, exhausted, running on coffee. If you had a year to transform their health and performance, what are the things that you would change?

3:18Dr. Mark Hyman:I would immediately have them get it.

3:22Hala Taha:Yeah, fam, what if aging wasn't something that just happened to you, but something you could actually control? What if the fatigue, the brain fog, the chronic conditions we've been told are just part of getting older are actually preventable? That's exactly what today's guest is here to talk about. Dr. Mark Hyman is a renowned functional medicine physician, best-selling author, and one of the leading voices in the science of longevity. His mission is simple, help people not just live longer, but better. In this conversation, Mark is going to share some science-backed insights to help you improve your health, extend your lifespan, and defy aging.

3:55Hala Taha:There's some serious gems in this one, so tune in and take notes. I'm so excited for this conversation, and there's so much to talk about, but I just want to jump in and get started. So I was reading your book, I was researching you, and I found out that you want to live to be 120 years old.

4:12Dr. Mark Hyman:Oh, if I can do everything I'd love to do, yes. If I can, no. Yeah. I'm still riding my bike at 119. I'll keep going. That would be amazing.

4:21Hala Taha:I also interviewed Dave Asprey a few times, and he tells me he wants to live to be 180 years old. So there's this trend of biohackers like you guys that want to live to be 120, 180 years old.

4:33Dr. Mark Hyman:I would just say I'm not a biohacker. I'm a functional medicine physician. And so I use deep science and it's not, I mean, some of the tools are similar, but it's functional medicine is really the ultimate biohacker.

4:44Hala Taha:Yes. Yes. And we're going to talk all about functional medicine, and I'm going to try to help my listeners understand what that is if they're not familiar. But you guys are on a quest to live as long as you can, right? Absolutely. So that's the two things that you guys have in common. Maybe it's not biohacking. But when I think about that, I think about frail, old, bedridden. Yeah, yeah. I don't, you know, really want to live to be 120 years old, at least by today's standards. So I want to understand, when you imagine yourself at 120 years old, what do you actually imagine yourself being capable to do?

5:17Hala Taha:What does 120-year-old and thriving look like?

5:22Dr. Mark Hyman:I mean, it means being able to do whatever you'd love to do. If it's sitting there rocking Jeremy to book, it's that. If it's hiking up a mountain, it's that. If it's making love with your partner, then it's that. So for me, it's really being able to get up in the morning and do what you love to do and not be encumbered by some of the conditions that are mostly preventable that we seem to think of as normal parts of aging. They're not really. And what's happening on the science is quite exciting. We're seeing a lot of research, for example, there's a Washington Post article recently about the Almanac factors, which is basically a scientific discovery that won the Nobel Prize.

5:54Dr. Mark Hyman:It allows you to reprogram your genes back to a younger you. It's called epigenetic reprogramming, and it's being researched by the Altos Lab and Jeff Bezos and also by Sam Allman's Lab. So there's a lot of really amazing research going on in this right now in the longevity space. That's going to be an unlock. For most of us, I think we can expect to get to our 90s or be 100, you know, big earth and good health if we know what to do to take care of our bodies. And I saw this all over the place. I mean, I was in Sardinia and I was in Icaria. And I just saw people who are, like, really old and really thriving.

6:26Dr. Mark Hyman:And, you know, this woman was, like, 87 years old. And she was, like, running up and down the side of this mountain. I couldn't keep up with her. She was tending to her giant gardens and farm and animals and trees. And, you know, it's quite amazing to see. So I think if we understand the things that impede our health, we can remove those. And if we understand the things that enhance our health, we can add those. And it's really not that hard. It's just knowing what to do.

6:51Hala Taha:Yeah. And I hope we can unpack some of that in this interview today. So I was listening to your audio book, Young Forever. It was really entertaining. and you were talking about how you went to Sardinia and went to the blue zones. But talk to us about what actually sparked your interest in longevity.

7:08Dr. Mark Hyman:Well, I've always been interested in the science of optimization in terms of how we function. I mean, whether it's the word functional medicine or the company I co-founded, Function Health, the core value is how do we unlock how to function at your best and how to unlock the keys to optimal biological performance. And it's really something that we're now only discovering. No one's really asked the question in medicine before. What is the definition of health? It's not the absence of disease. It's something else. And if you go to your doctor, you feel good, say, I want to feel better. I want to optimize my health.

7:46Dr. Mark Hyman:They don't know what to do. Like if you have symptoms, great. If you have a disease, they'll give you a drug. But do they understand the science of creating health? No. That's what I've spent my life studying after medical school. It's the science of creating health. And it's something we now know how to do. And that's what's so exciting. We know the basic biological systems that go awry. And in the field of longevity, the science is really getting exciting because we're talking about these concepts called the hallmarks of aging. The hallmarks of aging are these fundamental biological things that go wrong or break down as we get older that are underlying all disease.

8:19Dr. Mark Hyman:It's like the roots or the trunk. And all the branches and the leaves are all the diseases and all the specialties. So whether it's heart disease or cancer or diabetes or Alzheimer's or whatever it is, autism, depression, they share common roots. And there are only really a few things that impede health. You have to identify what those are. There are toxins, there's allergens, there's microbes that change your microbiome, which is physical or psychological stress, and poor diet, which is most of us eat. And then there's a few things our bodies need to thrive. So you need to get rid of the bad stuff and put in the good stuff.

8:49Dr. Mark Hyman:and then there's ways of even sort of accelerating the optimization of things for example like how do you optimize your mitochondria how do you optimize your microbiome how do you optimize your neurotransmitter function how do you optimize your immune system these are things that we now know how to do if you say to your doctor i want to optimize my mitochondria figure out how to optimize my immune system and they're not going to know what to do how do i optimize my microbiome take a probiotic you know eat fiber you know like they're not going to really understand because it's not what they do and i've spent the 40 years studying the function of the body and and that's really what we kind of have come to in terms of understanding how to create these shifts in our biology that create abundant and vibrant health and that don't provide a breeding ground for disease.

9:29So with traditional medicine, really they're focused on like a specialty, right?

9:34Hala Taha:They don't treat the whole body holistically. So can you give us an example of like, okay, I go to the doctor and I'm like, hey.

9:40Dr. Mark Hyman:I'll give you an example. I'll just tell you a patient, an actual patient I had. I'm not going to use her name, but she was a business coach about 50 years old. She was overweight, she had prediabetes, she had depression, she had migraines, she had reflux, she had irritable bowel, bloating. She had terrible psoriatic arthritis, which is a horrible condition where you get psoriasis all over your hands and skin and body. And you also get arthritis, which is debilitating. So she was on a drug for that that cost$50 ,000. She was seen by the best docs, one of the best healthcare centers in the world.

10:07Dr. Mark Hyman:And she was getting the best GI treatment for reflux, the best treatment for irritable bowel, the best treatment for depression, quote, the best meaning the best traditional view, the best treatment for migraines, the best treatment for her prediabetes, the best treatment for her psoriatic arthritis. And she was seeing a doctor for every inch of her. And no one said, what is linking all these problems together? For her, it was inflammation. She had tremendous amounts of inflammation that were driving all these conditions. Now, we know depression is inflammation, right? We know that if your gut's upset, it's inflammation.

10:37Dr. Mark Hyman:We know that, obviously, if you have inflamed skin and arthritis, that's inflammation so we know that diabetes is inflammation or prediabetes or obesity is inflammation so i said to myself well what are the root cause for her you know she was having so many gut issues that i believe those are the cause she had severe bloating she had all these history of taking antibiotics the steroids for various things like for her autoimmune condition i said why don't we just do something really simple rather than taking all these drugs you can continue to take them. But in the meantime, let's just try you on a whole foods, low sugar, low starch diet, which removes the common inflammatory triggers.

11:14Dr. Mark Hyman:And for my practice, for people who have autoimmune disease, getting rid of grains and beans, dairy, gluten, which is part of the grains, sugar, processed food, alcohol, really makes a difference. So I said, put her on that diet. I said, let's kind of reset your gut. I gave her an antibiotic and an antifungal to reset her gut. And then I gave her probiotics and things to rebuild her gut. And I gave her, I think, vitamin D and some fish oil, not a lot of stuff. And six weeks later, she comes back, says, Dr. Hyman, I got off all my drugs. I'm like, wait, I didn't tell you to do that. She said, no, no, I just was feeling so good.

11:45Dr. Mark Hyman:I just stopped everything. And she had no more cardiac arthritis, her skin care cleared up, she had no more migraines, she had no more depression. She lost 20 pounds. Her prediabetes was gone. Her reflux was gone. Her inner bowel was gone. And so I just treated the root cause, not the symptoms. And this inflammation is a common trigger for most chronic diseases. And for her, it was, you know, for me, after seeing this for, you know, 30, 40 years of patients like this, I can see it, you know, when they walk in, I know what's going on. And it's not that hard to treat, but she was getting all these symptom suppression treatments that weren't really working.

12:18Dr. Mark Hyman:They were marginally working. They were keeping her functioning, sort of, but they didn't really deal with the problem. So functional medicine is about really understanding the body as a network, as a system, as a system of systems that you have to keep optimized in order to live well. And they map almost entirely perfectly across the hallmarks of aging that scientists have been discovering. So when your mitochondria don't work, when your detox system doesn't work, when you have immune imbalances or hormone imbalances or neurotransmitter imbalances or your gut's off, these are things that we actually know how to treat.

12:49Dr. Mark Hyman:Your mitochondria aren't working. These are things we know how to treat with functional medicine.

12:52Hala Taha:And talk to us about how your company Function services these types of problems.

12:57Dr. Mark Hyman:What we've done with Function is really create the first health platform that allows people to fully access their own data. Now, people are wearing Oura rings, they're wearing Apple watches, they're wearing glucose monitors. That's all great. That's just a few data points. But what if you could unlock all of your biology? What if you could know all your biomarkers and your metabolome and your microbiome and your genome imaging, your wearables and your medical history and your EMR, your medical records, all gets into a platform that is personalized to you and allows you to identify where the imbalances are, where the dysfunctions are, and gives you deep insights and content based on machine learning AI to help you actually optimize your health for you.

13:38Dr. Mark Hyman:Because no two people are alike. And everybody's different. And if we try to treat to the mean, we often miss the mark. And this is what medicine does. It treats to the mean. There's no average person, right? And everybody's different. And the studies work by something called randomized control. no-blind trials, which means, control means you basically have two populations that are as identical to each other as possible. So you want to be a 70-kilogram white male from Kansas, and you get 100 of those people, and you put 51 group and a 50-another group, and you give them a drug, and you see what happens at the other side.

14:09Dr. Mark Hyman:That's how medicine operates. That 70-kilogram white male is not like 90 % of us out there. Not you, it's not me. And so how do we move towards where medicine is going, which is personalization. We call precision medicine, personalized medicine, whatever you want to call it. It's where we're going. And so Function Health is the first platform that is able to actually do this for you in an amazing way that helps people revolutionize their health. And we just started, honestly, this is a startup. And we didn't realize how much success we were going to have. And so, you know, we have almost 150 ,000 members.

14:42Dr. Mark Hyman:We have, you know, millions, tens of millions of data points on people. We're seeing all kinds of trends in the data. We see that people actually, you know, when they get their first test, and now we've been going two years, we can see that when they follow up and do the follow-up testing, that their biomarkers get better, their blood sugar gets better, their cholesterol gets better, their inflammation gets better, their vitamin D gets better, whatever is off. And we give them a deep dive into what's going on with their biology, not just from a traditional perspective, a traditional sort of Western medical perspective, but also this emerging field of systems network and medicine, which is what functional medicine has been doing.

15:17Dr. Mark Hyman:But now the rest of the science is catching up, which is very, very exciting to me.

15:24Hala Taha:Yeah, Pam, when I started my business as a side hustle, I was working full time at Disney. But once I started bringing consistent revenue and I had retainer clients, I knew it was time to go full swing into entrepreneurship. But nobody warns you about all the unsexy and complicated stuff you need to start a business. But luckily, this is exactly what Northwest Registered Agent is built for. They are the largest registered agent and LLC service in the U.S. And they've been helping entrepreneurs launch and grow legit, protected businesses for nearly 30 years. When you form with Northwest, you get a complete business identity.

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15:58Hala Taha:That includes a business address, a registered agent service, which, by the way, is really important. It makes sure that you know if you're getting sued and things like that, an operating agreement, professional email, domain, website, phone number, and built-in privacy. All in one place, all handled in-house. And the best part is you get thousands of free guides, tools, and attorney-drafted documents to help you run your business with confidence. Don't pay hundreds or thousands of dollars for what you can get from Northwest for free. Visit northwestregisteredagent.com slash yapfree and start using free resources to build something amazing.

16:31Hala Taha:Get more with Northwest Registered Agent at northwestregisteredagent.com slash yapfree.

16:40Hala Taha:Yap gang, do you want to look and feel your best this summer? And I don't just mean looking good on the outside. I mean feeling amazing from the inside all the way down to your cells. cells. Yep, your cells. If you do, I'm going to put you on to a reset that I've been absolutely obsessed with. It's Prolon's five-day fasting mimicking diet. Prolon is a plant-based nutrition program with soups, snacks, and beverages that keep your body in a fasting state while still nourishing you. It is the only nutrition program clinically proven to trigger autophagy, your body's natural cellular cleanup mechanism.

17:15Hala Taha:And autophagy can support longevity and it can even reverse your biological age. For the last couple of years, I've known about it, but I was always scared to actually do a fast because I work out a lot. I didn't want to lose muscle. And honestly, not eating for days sounds way too hard. But then with my birthday coming up, I wanted a Risa. I wanted to lose like five pounds. I wanted more energy and to look my best. And that's how I came across Prolon. And everything comes prepackaged, labeled day by day. There's no prep, no planning, no guessing. And I loved it so much that now I'm planning to do it three times a year.

17:49Hala Taha:With Prolon, I'll be young and profiting forever because with three resets, you can actually reverse your age by 2.5 years, which is just insane. That means every year I'll basically be getting younger. If you're ready for your own reset for a limited time, Prolon is offering young and profiting listeners 15 % off site-wide plus a$40 bonus gift when you subscribe to their five-day program. Just visit prolonlife.com slash profiting. That's P-R-O-L-O-N-L-I-F dot com slash profiting. prolonlife.com slash profiting. To claim your 15 % off discount and your bonus gift. prolonlife.com slash profiting.

18:28Hala Taha:Yeah, fam, as my business keeps growing, I feel like I'm always hiring. I recently added two new video editors and a producer to my team. And I can tell you from experience, the right hire can give you leverage. The wrong hire gives you a second job. And that's the last thing you need. So when I need the right person, I go to Indeed Sponsored Jobs. Indeed Sponsored Jobs boost your job posts and search results so you can reach candidates who meet your specific criteria, like skills, certifications, location, and more. Because the goal is not more resumes. The goal is better matches. Spend less time searching and more time actually interviewing candidates who check all of your boxes.

19:05Hala Taha:Less stress, less time, more results. When you need the right person to cut through the chaos, this is a job for Indeed Sponsored Jobs. And listeners of this show will get a$75 sponsored job credit to help get your job the premium status it deserves at Indeed.com slash podcast. Just go to Indeed.com slash podcast right now and support our show by saying you heard about Indeed on this podcast. Indeed.com slash podcast. Terms and conditions apply. Need to hire? This is a job for Indeed Sponsored Jobs. My first question to you, I mentioned biohacking and you kind of like got like a little offended when I when I when I tried to compare what you were doing with biohacking.

19:43Hala Taha:But when I hear you talking about it and you're talking about personalization and figuring out like, you know, your biologically to me, that's you know, I've been doing this podcast for six years and had a lot of people on the show. And it sounds a lot like biohacking. So so what's the difference?

19:56Dr. Mark Hyman:Well, I think biohacking tends to be around things like hot and cold plunges, hyperbaric chambers, red light therapy, all these devices and tools and things to optimize your health, which are fine. They work and they're mediated by biological processes, and I use those. However, if someone comes in like that woman that I just described to you, no biohacker in the world is going to fix her because they don't understand the science around functional medicine. Now, if they're a trained practitioner, fine. They'll figure it out. Hopefully, they'll figure it out. But when you just use these modalities without trying to understand what the underlying root cause is, it's another symptomatic treatment.

20:36Dr. Mark Hyman:You might feel better for a little bit. You go on a sauna. You go on a cold punch. You feel good. But then what? You still have your arthritis. You still have autoimmune disease. You still have your migraine. You still have whatever you got. And no one's telling you how to figure out the root of that. So I'm not opposed to it. And Dave's a good friend. And I love Dave Asprey. And we hang out and talk all the time. And I learned from him. I mean, there's other, there's all kinds of great tools that I personally use and have. I'm just saying that functional medicine is sort of the OG biohacking in a sense, because it's really about understanding at a much deeper level what's going on biologically, biochemically, genetically, you know, with your microbiome and ways that I think, you know, most people just, it's a lot to take in.

21:15Dr. Mark Hyman:And the problem is, you know, there's 37 billion, billion chemical reactions to your body every second. Nobody can understand all that. You have tens of thousands of metabolites in your blood and chemicals. We do 19 on a regular panel. With Functional Health, we do$499, which is$15 ,000 to test for less than$500. And you get over 110 biomarkers. And you can add on other things as well to go deeper dives into whether you're exposed to chemicals, whether you're at Alzheimer's risk, whether you have immune issues. I mean, so whether you have Lyme disease, we provide you a really deep, robust platform where you get to be driving the bus.

21:47Dr. Mark Hyman:You don't have to go to a doctor. You don't have to ask for permission. You don't have to beg for the requisition. You have to go to the, you know, try to find a lab that will order you to get, you know, your insurance to pay for it. I mean, I have insurance. I go to the lab and my doctor ordered some stuff that I wanted to do. And it was outside of Function. And she's like, well, it'll pay for this test, but not this test, and this test, but not this test. You know, I'd be charged for that. You'd be charged. I'm like, oh, you know, it's like, but that's what Function solves all of that. And you have this beautiful integrated dashboard where you have your data forever and you track it over time.

22:16Dr. Mark Hyman:You get an app which helps give you direct feedback. and it's a very, very integrated experience into your life.

22:22Hala Taha:Yeah. And I feel like it's really needed because to your point, the rest of the medical world is kind of stuck in this traditional process that really isn't working. And the other thing that's not working is actually treating aging's symptoms and not the root cause. And one of the other big principles that you talk about is treating aging like an actual disease. So why is that important?

22:42Dr. Mark Hyman:Well, I think you come to sort of accept that as you get older, you have cancer, you get heart disease, you get diabetes, you lose muscle, your brain function declines, you lose your ability to do things. These are not normal consequences of aging. Frailty is not a normal consequence of aging. It's a consequence, a phenomenon that happens as we get older if we don't do something about it. And all of us have seen those 90-year-old ladies doing gymnastics, the 100-year-old people running the 100-yard dash. It's kind of crazy stuff like that, right? And so what is it about those people? Well, they have understood by accident or by studying that there are certain behaviors that foster optimal health.

23:25Dr. Mark Hyman:It's eating whole foods, unprocessed diet. It's low sugar and low starch and full of phytochemicals and fiber and got to with some amounts of protein, especially more protein than animal protein as you get older because it's harder to assimilate and build. You need to make sure you exercise and do strength training and you need flexibility. You need cardiovascular training and stability training. They understand you need good sleep. They understand they have managed their stress and their own emotional regulation. And they also have deep social connections and relationships that foster a sense of belonging, which all are ingredients for optimal health.

23:57Dr. Mark Hyman:And when you look at people like in the blue zones, that's basically what they have. It's not that they were vegans or not vegan. It was that they had these other factors and that they were profoundly impacted just by default by these situations that they found themselves born into. which we totally in the West don't have. Like we're the opposite. We have dysregulated sleep schedules. We have tremendous amounts of stress. We eat crappy food. You know, we don't exercise enough. We, you know, like we got my R-ring told me I didn't exercise enough yesterday. I was a busy day. So, you know, there's all these things that we're doing to impede our ability to actually live a vibrant, long, healthy life.

24:32Hala Taha:Well, you seem to be doing a good job because your biological age is 43, but you're in your 60s. Is that right?

24:40Dr. Mark Hyman:Yeah, well, I got my biological age done. when I was 62 and I was 43, then I implemented more of the things that I learned and some, you know, some other strategies. And I went, I got two years older at 64 and I redid my biological age. It was 39. So I went, even though I got two years older chronologically, I got four years younger biologically. So that's, that's the power we have. And this is what we call epigenetic reprogramming. Now I mentioned earlier, the Aminaka factors and so forth. These are, these are sort of behind the sky things that have to be tested in humans and make sure they're safe and effective but right now i mean even with what we know by optimizing and tweaking you can actually still reverse your epigenetic biological age at any point in your life and you can it's it's it can go backwards or forwards you know like if you kind of go on a bender or whatever you don't sleep and you party and you eat crappy food you'll get older biologically and then you can change that and reprogram and go back i wouldn't recommend that give us like concrete things like what did

25:39Hala Taha:you do to reverse your age 20 years?

25:43Dr. Mark Hyman:Well, I've been doing this my whole life. So it wasn't like I was 64 and then I, uh, biologically, and then I, in five years, I reversed it to 43. So, okay. I, I have been eating whole foods my whole life. I've been not eating processed foods. I don't remember the last time I had a Zoda. I mean, I probably was a kid. Uh, I exercised my entire life for the last 50 years. I have, um, you know, make sure I prioritize community connection, sleep and and and men's stress and and all those things play a role and then i've done things to optimize my microbiome my mitochondria my immune system and those are all really help so all those things kind of just kind of nudge you back into a healthier state and there's some supplements and things i've taken i think can have made a difference i've taken neural fna i take uh amino acids that help be assimilated i also take um something that's called nmn which is a precursor of NAD that helps also revitalize your cells.

26:40Dr. Mark Hyman:So I do a number of different things that I think are important from a supplement perspective, but I think most of it's, that's like the 10%. It's like the rest of it is the 80 to 90%.

26:51Hala Taha:And that's what, if we were to use function, the platform, it would help us figure out like, okay, what's our biological age? And like, these are the things you need to do really to function and to help. That's what it does.

27:03Dr. Mark Hyman:Yeah, we do a calculation based on your biomarkers of what your biological age is based on scientific data that shows certain blood biomarkers correlate with your epigenetic biological age. And you can see it go backwards or forwards. Now, if you do different tests, you're going to get different numbers, right? Some tests will be like five years younger or 10 years younger. And so you may not kind of be able to compare apples to apples by switching tests. But if you stay with the same tests consistently, you'll see the changes. Yeah.

27:32Hala Taha:Okay. So I want to get really nerdy because I'm sure people have been listening and they're like, I have no idea what epigenetics is. And so there's two terms I want you to break down, epigenomes and exposome, right? I know that. So one is about how genes are expressed. One is our environmental exposure. So break those down.

27:49Dr. Mark Hyman:Yeah. So basically the concept that I think is really important called the exposome. We all have been taught that our genes control who we are. They're our destiny. Whatever we got, we got. We can't change it. You know, our parents got diabetes. Our parents got cancer. or our parents got whatever heart disease it's just kind of in our future your genes are not your destiny they're they may provide you with a roadmap of what your predispositions are but not your destiny so what controls your destiny it's something called the exposal that is a sum total of everything that you're exposed to throughout your life that washes over your biology including your genes and reprograms them based on what you're doing if you're eating like me if you you had a whole foods diet, if you exercise, you do all these things for 50 years, you're going to be biologically younger.

28:33Dr. Mark Hyman:Your epigenetics are going to track as if you're younger. And I'll talk about what epigenetics are. So the exposome is what you eat. It's your exercise, your nutrient levels. It's stress management. It's community. It's sleep. It's all the things we've just talked about. Light, air, water, all those things. I went on bright sunlight this morning for 20 minutes. All those things matter. That influences how your biology is regulated. We're biological organisms, and we're controlled in the same way by our external factors. So the exposome is literally everything from toxins to your gut microbiome to your diet to sleep, everything that your body is exposed to.

29:09Dr. Mark Hyman:That's why we call it the exposome. Your epigenome is how the exposome regulates your biology. Now, what is the epigenome? Epi means above. So you've got your genes. You've got about 20 ,000 genes. uh your epigenome and then think about like the uh the keyboards on a on a on a piano right you got 88 keys they ain't changing you know i got 20 000 genes they ain't changing unless i do gene editing or splicing or some other weird thing that's coming around the corner they're not changing what can change is how those genes are expressed how they're turned on or off whether they're upregulated or downregulated whether they drive inflammation or stop inflammation whether they're accelerating aging or slow aging.

29:50Dr. Mark Hyman:And they are basically the control mechanisms to turn on or off genes. So think of them like switches or knobs. And you can dial them up or down based on what you're doing. And that's how almost all of the impacts of a lot of the lung practices we talked about have their effect. That's how the exposome regulates your health and lung severity, your biology, and your risk of disease. is through your epigenome, then translates into the expression of genes and proteins and biological functions. And you want to have a healthy epigenome. And, you know, there was a great example, for example, a brand new journal who discovered this kind of phenomenon was these mice that are bred to be obese.

30:30Dr. Mark Hyman:So they're yellow, they're fat, basically yellow fat mice. He gave a series of the females who are pregnant certain nutrients called methylating nutrients that regulate the epigenome. So it's a little complicated, but there's something called methylation, which is a chemical process that regulates your genes. It involves B6, folate, and B12. So vitamins and minerals are extremely important. They run everything in your body. Every biochemical reaction needs a vitamin or mineral. And if you don't have them or they're insufficient, you're going to have gummed up biochemistry. And gummed up biochemistry translates into disease.

31:02Dr. Mark Hyman:So he basically gave these pregnant mice some B vitamins and a few other amino acids and things to help to support this process. The offspring were perfect. They were thin. They were healthy. They were gray. They were not yellow fat mice, even though genetically they were bred to be yellow fat mice. And this was a massive discovery. And I think this is what really has led to our understanding of this whole process of how we can modify our epigenome and the outcomes. So when your mother's eating when she's pregnant with you, you know, the stresses you experience in utero that your mother might have experienced or all your early childhood experiences.

31:42Dr. Mark Hyman:All those imprint on your epigenome and can affect you, toxins you're exposed to. So this is why we have to pay attention to how we live, because if we want to feel good and do good and engage in life and do the work we want to do and be successful in our work and have great relationships and enjoy life and be happy, if you feel like crap, it's not that much fun.

32:02Hala Taha:Yeah, so true. And so from what I read like 90 % of disease and aging risks has to do with our environment, our, our exposome, right? And so the earlier that we start, the better is what you were just saying, right? We can even start from in the womb if our, if our, if our mothers are smart enough.

32:21Dr. Mark Hyman:That's right. Yeah. You know, like, uh, you know, I've seen, you know, women wanting to be pregnant. I mentioned their toxin load. I'm like, Whoa, we got to do something about this. We got to reduce your exposures, the toxins. You've got to get these heavy metals down because you want have a healthy baby. And so we really proactively do preconception work. I had a whole podcast about that on the doctor's pharmacy, and now it's called the Dr. Hyman Show. And we dove deep into what you need to know preparing for a baby, what happens when you're pregnant, how do you take care of yourself, what are the things that matter scientifically to optimize the chance of having a healthy baby.

32:52Hala Taha:On the flip side, is there any time that's like too late to get started on this?

32:57Dr. Mark Hyman:Oh, God, no. I mean, what's really amazing, in none of the animal studies, they've given rapamycin which is something that is a drug discovered in rapinui that inhibits this pathway called one of the longevity switches i call longevity switches uh that they control so much so mTOR is one of these and mTOR essentially is a pathway that is going to help you build muscle but also when it's activated and when it's inactivated or or inhibited in some way it's going to allow the cells to replenish repair called uh through this process called autophagy which basically means you're eating your old cells and you're reusing the parts it's recycling so it's cleaning up the mess that we make all the time in our bodies where does that garbage go right if somebody has to fix it so rapamycin inhibits that and accelerates the autophagy process and then given in the right ways it extends life and extends health in in animal models consistently and reliably uh and so there are there are interesting ways that we can sort of activate these longevity switches and pathways and i talk about that a lot in my book young forever.

33:57Dr. Mark Hyman:And how do we understand how these work, what we can do? And it's not complicated. There's a few simple practices, sometimes a few supplements that can really help modulate some of these pathways to activate the longevity switches.

34:09Hala Taha:Okay. So one more really nerdy question, and that's about mitochondria. So you say the difference between a three-year-old and a 90-year-old is the number and the state of their mitochondria. So help us understand what mitochondrial dysfunction has to do with aging. Yeah.

34:23Dr. Mark Hyman:Great, great question. So this is one of the hallmarks of aging is mitochondria function it's key to so many diseases your mitochondria i think of them like the powerhouse of your cell the energy factories they take food and oxygen turn into energy that your body uses and we use you know gasoline or carb um and it combusts and you know creates energy it what we run on is something called atp it's just a molecule produced from food and oxygen and the waste products are carbon dioxide which we breathe out and water which we pee out and some free radicals which we have antioxidant mechanisms to control and what happens is they're your energy, right?

34:55Dr. Mark Hyman:So if you have poor functioning mitochondria, you're going to have low energy. You're going to be weaker, you're going to have lower muscle mass. So the key to longevity is keeping your mitochondria healthy and keeping them strong and actually having better, more mitochondria. And so the way to do that is by exercise. So resistance training builds muscle in mitochondria. Sprint training or HIIT training does that as well. Exercise with oxygen therapy. Hypoxia training does that. There's a lot of ways to do it. There's supplements like urolithin A, which has caused mitophagy and mitochondrial renewal.

35:27Dr. Mark Hyman:Their mitochondrial support supplements sometimes that you need. So there are a lot of ways to optimize your mitochondria, but they're injured by too much food, too much sugar and starch, too many environmental toxins. All those things from the microbiome that are bad, all those things can damage your mitochondria. So learning about your mitochondria, how to take care of them is really important. And again, it's one of the things we kind of can look at as we start to test things and see what's going on in our bodies.

35:50Hala Taha:So interesting.

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37:51Hala Taha:Shopify lets you build your store, market your products, manage payments, track analytics, and handle shipping returns and inventory all in one place. Shopify does this all so you don't have to do it alone. Start your business today with the industry's best business partner, Shopify, and start hearing. Sign up for your$1 per month trial today at shopify.com slash profiting. Go to shopify.com slash profiting. That's shopify.com slash profiting. Okay. I want to talk about your drive of wanting to live so long. Because one of the factors that you mentioned is like having a purpose and feeling like, you know, you've got a way to contribute to the world.

38:33Hala Taha:So why do you actually want to live so long?

38:35Dr. Mark Hyman:Well, I love life. And as long as I can enjoy life and be with my friends and do the things I love and ride my bike and hike and enjoy what I'm doing and have meaning and purpose and contribute to the world and add value. I'm 65. I kind of figured a few things out by now. Wisdom always doesn't come with age, but I've had a bunch of hard knocks, and that's really taught me a lot. And so I kind of feel happy and content and satisfied, and I want to keep going. So I mean, I don't really care if I get to 120 or 100 or 99 or 95 or 90. I just want to feel good and do good.

39:09Hala Taha:It makes a lot of sense. And I'm really excited for this generation of 60-year-olds because I just feel like in the past, you know, when you're in your 60s, it's all about like retirement. And I feel like a lot of people right now are actually like taking on second careers and realizing that they really have a lot more time to live and people are taking advantage of that. So like, what are your thoughts in terms of people around your age who like want to take on a new career or? Yeah. Yeah. Tell me.

39:37Dr. Mark Hyman:I mean, I, you know, I'm 65 and two years ago, I co-founded a company that's a big startup company right now. So, I mean, who does startups in their sixties? Most people are like looking at golf courses and not startups. And, and I, I mean, I want to contribute to the world. I want to do things. I get excited. We're building, we're creating, we're, we're dreaming. We're imagining a different future for healthcare and medicine. We're adding value to people's lives. I mean, it's something to get up for every morning and be excited about and take all the things that I know that are almost impossible for any single doctor to synthesize and to sort through and make sense of and provide each individual with a personalized approach to their health that's going to actually optimize how they feel.

40:20Dr. Mark Hyman:And that's really the key here is to end needless suffering. And for me, that's my purpose. And that's my mission. and plus having fun, enjoying my life and my wife and everybody around me.

40:30Hala Taha:Yeah, I love that. So it's hard for me to imagine at the same time, like I see people living older, but it's also hard for me to imagine, especially in the West, because I feel like things are more unhealthy than ever. The food in the grocery store is terrible. It's like everything comes in a cardboard box. Our water supply is really scary and it feels like there's no good water. It's either like you're getting plastic or you're drinking from, you know, a dirty faucet, right? And so for me, it just feels almost impossible to kind of navigate food, which you say is medicine. So talk to us about how we should try to navigate our diets and also like maybe like what changes need to happen in America for us to actually live healthier lives and longer lives.

41:18Dr. Mark Hyman:This is something I've been working on for a long time. And I wrote a book called Food Fix, which lays out from field to fork what's wrong with our food system. And, you know, if there's one thing that's killing us, aside from environmental toxins and stress and our sleep schedule, it's probably 80 % food. And it's something that we can control and do something about. And unless we actually take it seriously and fix our food system, we're kind of in a mess. And so right now there's a resurgence of interest in health around the country. There's the Make America Healthy Again movement. And so there's an energy happening.

41:49Dr. Mark Hyman:And in Washington, working on policies to bring those changes to the average American. For example, in West Virginia, they got rid of red dyes and other dyes. In California, they did the same thing. These are great steps to start to push the food system to produce healthier food for all of us.

42:04Hala Taha:And something that's really hot right now is GLPs, right? I have mixed feelings about them. I feel like it's good for personal. I'm not a doctor, right? But I think it's good if you have a real problem. but I see normal people who might just need to lose 10, 20 pounds take GLP. So what are your thoughts around that?

42:23Dr. Mark Hyman:I think for most people, and I literally just got a text from somebody this morning saying, my cousin read your book. They lost a hundred pounds. My, my person's working with me in Washington around food policy. She lost 112 pounds in the last few years working with me. And without taking any trucks. Now, some people are really stuck. And if you're stuck and you need help and you have not really addressed the underlying reasons why you eat that. Sometimes it's not what you're eating, it's what's eating you. You got to figure that out. It's really important to do that. And I think when people do that, they don't necessarily have to take these drugs, which are helpful.

43:00Dr. Mark Hyman:They can be extremely helpful, but they also come with side effects, muscle loss, weight regain if you stop. They can have other issues, like pancreatic issues and pancreatitis. They can cause bowel obstruction if you're taking it for a long time. So they can be a good tool, but they're just a tool. They're not a panacea. And I think they've helped a lot of people. I'm not against them. I think they're kind of used in ways that sometimes don't make sense to me. Why give a six-year-old an ozempic shot for the rest of his life? It's not his fault he's overweight. It's the environment he's in. And I think that can actually get really fixed.

43:34Dr. Mark Hyman:So I think it's important for people to understand that they have power. The food industry has basically hijacked our brain chemistry, our metabolism, our desires for different foods. And these are things that can actually be changed. You can literally change your brain chemistry and have an incredibly powerful shift in your cravings and your desire for foods. For example, people going keto, they don't really need OZM because naturally the way they're eating will shut off that craving. And the food addiction is a real thing. About 14 % of adults and kids are addicted to food, biologically addicted.

44:17Dr. Mark Hyman:This is really based on good evidence from Yale Food Addiction Scale and deep science around the world. We looked at this. This is just horribly sad and horribly unfortunate because we really don't need to do that. We can fix our food supply. We can fix this problem. And it has to be done at a grassroots level. It has to be on a state level. It has to be on a federal level. It's going to take time. But we're working with the FDA, working with the USDA, with HHS, the administration as best we can to try to push changes through my nonprofit.

44:49Hala Taha:I've also heard that there's food companies already trying to figure out how to like circumvent GLPs so that people still crave their food, right? So this is going to figure out how to get around it.

45:00Dr. Mark Hyman:That's even crazy when you think of it. Like, wow, they're really just going to go there? They're literally going to just kind of circumvent Ozempic by making food even more addictive.

45:11Hala Taha:Yeah, that's the state of the world that we're in. So we've got to take control. So let's talk about our ancestors. Because when I was listening to your book, I was surprised because we're always thinking about how we live so long now. And when you think about the past, you might think like people died at like 30, 40. But there's actually cases in history where people have lived to be a very old age. So talk to us about how our ancestors ate and maybe some examples of people who lived really long back in the day.

45:39Dr. Mark Hyman:I think, you know, when you look, for example, at the Native Americans, one of the longest populations in the world at the turn of the 1900s was the Plains Indians. They had almost most of their diet from bison. And then they had berries and they had probably wild stuff they gathered. But predominantly their diet was meat. and they live to be like well over 100 and highly functional and active and you know the these populations around the world where you see people like i was in turkey and they know this is not a technical blue zone but man they were a lot of really old people who are doing great you know we're in their 80s 90s still working still thriving still make part of their community and i think it's when you stop you stop like i think retirement is the worst idea ever invented you know i don't really get it but but you know people don't retire they just shift and change what they're doing.

46:31Dr. Mark Hyman:And I think in these communities, and when you see these people living to be very old, it's because they found meaning, purpose. They've learned how to not sort of internalize the stresses of life. They've learned how to modulate their own diet and lifestyle to optimize their health. And they just kind of figured it out.

46:48Hala Taha:Let's stick on community a bit because you say it's also a factor in longevity. You say you're only as healthy as your five closest friends. Tell us about it. Yeah.

46:58Dr. Mark Hyman:Well, think about it. If all your friends are, you know, going to McDonald's and drinking beer and, you know, 202 liters of soda a day and watching TV all the time, that's kind of what you're going to be probably like. And if you have friends who are healthy and go to yoga and drink green juices and exercise and eat whole foods and, you know, get together and share these things, then you're more likely going to be healthy. uh and it's just it's just so clear christakis from harvard did a lot of work on this he wrote a book called connected but he published research in the new england journal of medicine showing that for example from the framingham data which is a large study of one of the largest studies long-scoring studies in the world uh in framingham massachusetts tracking their population he found that those people who actually um when they looked at the patterns around obesity that you were about you know 40 percent likely to be overweight if your parents or siblings were overweight but you are 171 % more likely to be overweight if your friends are overweight.

47:57Hala Taha:Wow.

47:57Dr. Mark Hyman:Yeah. So your social connections matter and your relationships matter. You know, like, I mean, if you're a, if you're somebody who just stays up all night playing video games and you're living in America and your friends are playing video games in, in Australia, I mean, your sleep, wake cycle, your circadian rhythm, everything's going to be off. So the people in the communities that you have to surround yourself with, make sure are people who are leaning in towards wellness and health as opposed to, you know, not that.

48:24Hala Taha:That's so interesting. Now, I don't want everybody tuning in to like become like fat phobic, you know, like we've got, but at the same time, you've got to pay attention to your, it's the same thing. If people are like doing drugs around you, you're more likely to do drugs. So food can also be as bad as a drug. We've got to think of it that way. So if there was one thing that you could remove from the grocery stores, what would it be?

48:49Dr. Mark Hyman:It would be high fructose corn syrup. Like that, you'd kind of cut out most of the in the grocery store. Yeah, that's probably what I would do. Yeah.

49:01Hala Taha:And then what is your, oh, go ahead.

49:04Dr. Mark Hyman:No, that's what I would, I think, you know, trans fats have been removed for the most part, which is great.

49:13but you want to make sure you're getting rid of those two things, trans fats and

49:19Dr. Mark Hyman:africanous corn syrup. Just getting rid of that alone will make a huge difference. Or just even reading the ingredient list. If there's an ingredient on there that you don't have at home that you wouldn't use in your kitchen, like betylated hydroxychloroquine or maltodextrin or mono and diglycerides, you probably shouldn't eat it.

49:38Hala Taha:I heard something once, if you can't kill it or grow it, you shouldn't eat it. And I always like think about that when I'm eating food. Yeah, totally right. So a lot of our listeners are entrepreneurs. They have very busy schedules. Sometimes it can get really overwhelming trying to follow different nutrition advice. So in the simplest terms, what should we be eating?

50:00Dr. Mark Hyman:I've written so many books about this food. What should I eat? the pegan diet, which is sort of a condensed version and with some kind of fun stuff in it. And it's really, you know, what we agree on is more than what we disagree on. You know, you can get on the margins about vegan or paleo or keto or this or that. But the truth is, we all agree we shouldn't be eating processed, ultra processed, but we all agree we should be reducing starch and sugar and refined carbohydrates in our diet. We shouldn't be eating things that aren't food technically, like, you know, maltodextrin or, you know, butylated hydroxychloroquine, We eat a red dye number three.

50:33Dr. Mark Hyman:We should be eating foods that are high in phytochemicals, that we think of as food as medicine, where it changes everything in our biology in real time. We should be thinking about having good quality fats from nuts and seeds and avocados and wild fish, small fish. And even for some people to tolerate animal fats very well, especially if it's regeneratively raised. They have very different qualities of fats. So there's a lot of really good things you can do that are available from the diet that you can get even anywhere. I mean, I've worked with people in the worst food deserts in America, and they've actually been able to make a huge impact and change their diet if they actually do the right things.

51:13Dr. Mark Hyman:And they will. They'll actually have a huge shift in their diet by actually doing this. So I'm pretty thrilled by how simple it is. But when people understand how to do it, then it often changes.

51:28Hala Taha:Okay, so talk to us about exercise. I feel like there's a lot of mixed advice when it comes to exercise. What's your take on the right amount, too much exercise?

51:39Dr. Mark Hyman:I think exercise is critical. Your body needs to move. There's no doubt about it. We were designed to be moving organisms all the time. And that's kind of how we evolved. now most of us don't do enough and that's unfortunate um and i think you know we don't uh i think i think eight percent get the optimal amount 23 percent we get some moderate amount but the the key is to actually um understand what's good for you and it's different at different times your life you know but i think you need at least 30 minutes of good cardio four or five times a week three times a week is strength training probably a week or a day or two of flexibility and training and stability training.

52:18Dr. Mark Hyman:That's kind of bare minimum. If you can do that, you're going to maintain your health and be good for a long time.

52:24Hala Taha:You've said in the past that strength training is the best anti-aging medicine. What's so good about it?

52:29Dr. Mark Hyman:Because what you're doing is you're building muscle, you're building mitochondria, you're increasing muscle mass. And what really kills people is frailty. When you get older, you get frail. You're not able to get up out of a chair. You're not able to do what you love to do. Your mobility has decreased. Your functions decreased. That's all totally preventable by strength training. And you have to work harder as you get older because the body doesn't really, unfortunately, it doesn't work as well. So you have to do a little more effort to get the same benefit. And I think that's, you know, that's, that's, that's something people have to do, but it's, it's not optional.

53:01Dr. Mark Hyman:Like exercise is just not optional.

53:03Hala Taha:I agree. Okay. Last question for you. And then we're going to close out this interview. So the average listener's age on my podcast is 35 years old and they're typically an entrepreneur. So let's say he gave you a 35 five-year-old, they're stressed, exhausted, running on coffee. If you had a year to transform their health and performance, what are the things that you would change?

53:26Dr. Mark Hyman:I would immediately have them get on a whole foods diet that I just talked about. I'd have them just follow the principles of eat real food, low sugar starch, good fats, adequate protein for where you are in your life phase and varies depending on where you are. Lots of phytochemicals, lots of fiber, and just start there. And if you're really having any health issues, I'd probably do my 10-day detox program, which is essentially a reset. It's just 10daydetox.com with the 10-day detox. And what really is amazing about it is that people get a reset. It's like putting your body back to its original factory settings, and you can see where food is impacting you.

54:02Dr. Mark Hyman:Oh, I didn't know that, oh, my rash was caused by food, or I didn't know that my migraines were caused by what I was eating, or I didn't know that my joint pain was caused by anything, or my sleep problem was caused by eating. So you get a really quick reset and then you can start to add foods back in. So that would be number one, get your food straight. And that's timing, planning, organizing. It's really important. The amount of time you spend on your business, the fraction of that you spend on your health, you'll get a lot of dividends from that. Get in a regular exercise routine. Not that hard.

54:29Dr. Mark Hyman:Maybe if you just want to walk 30 minutes, a few walking phone calls, that's good, better than nothing. You can have a walking treadmill. You can do more fun things. I like to bike. I like to do more mountain biking and road biking and tennis and other things that kind of are fun for me. I like to make exercise fun. Strength training, I've gotten into more and more, and it's been profound in terms of effect on my body, even as I'm older. I think learning how to regulate your nervous system is important. Self-soothing is not something we learn how to do. We get activated, reactive, but learning how to practice, whether it's breath work or meditation or some practice where you're resetting your nervous system because we're all in parasympathetic uh deficit we need to be relaxing more and then i think build community because you know as you're building something and going through stuff you know when getting isolated is the worst thing you can do for a human being and so i think having that ability to sort of work with uh your friends to kind of build a fun community experience is really important and that's something that you know it's been really important to me especially as i've gotten older is just invest in your friendships because when everything else goes, that's what will be left.

55:36Yeah.

55:37Hala Taha:So that was great advice on an individual level. And a lot of the people tuning in are entrepreneurs and we help move society forward. And, you know, we have this big shift from traditional to functional medicine. We're trying to combat the food industries. Can you talk to us about some of the opportunities that you see for entrepreneurs to kind of capitalize on all these changes?

55:57Dr. Mark Hyman:Well, I think, you know, the health and wellness market is a trillion dollar market. and you know there's a lot of ways people are entering that but you can figure out you know what you love and the intersection of what you love and you know what people need often businesses are started from people's own needs like i need to i need to fix my own health so i as a physician i got very sick when i was in my 30s i got chronic fatigue syndrome from heavy metals and i was struggling a lot and i had to actually sort of figure it out and that forced me to learn about what i learned about it forced me to study the way i studied to actually find this field of functional medicine to use it on myself to heal and repair and so that's that's kind of what i encourage you to do is figure out that intersection of what you love that's just driven me because it's not like a choice i don't have a choice like i'm you know making widgets or something that it's fine to make widgets we all need widgets but the key is really is really to kind of uh figure out how you can do this in a way that it syncs with what you love, because otherwise you won't really do it.

57:00Hala Taha:Great advice. Okay. So I end my show with two questions. I ask all my guests. It could be like totally different from what we talked about today. Just answer from your heart. So what is one actionable thing our young and profiters can do today to become more profitable tomorrow?

57:15Dr. Mark Hyman:Well, what your success is really determined by the quality of how you feel. So if you're able to function at a high level and do the things you want to do and not be held back by illness or struggles, you're going to be able to function at a much higher level and do whatever you want to do, whether it's just kind of buzz off and go kind of get early retirement or whether it's you want to build a company or whatever you want to do. You know, you have the capacity to be highly functional when you feel better. And so investing in your health is such an important thing from my perspective. Like, you know, I see a lot of people who have great businesses and companies and they build these things.

57:53Dr. Mark Hyman:They're rich. They have all this stuff and they're lonely. They're isolated. They're unhealthy. They're sick. They don't feel good. I mean, that is the last thing you want, right?

58:01Hala Taha:Totally. And your book, Young Forever, really is just like a blueprint for how to do that.

58:07Dr. Mark Hyman:Absolutely.

58:08Hala Taha:Yeah. And what would you say your secret to profiting in life is? And this can go beyond business.

58:13Dr. Mark Hyman:I mean, the secret of profiting in life, again, is to focus on the things you love and to do what you're passionate about. Because, you know, if you try to force something in your life, you know, the best things that happen are often serendipitous. They often come to you, their ideas, their people, their experiences. I feel like there's sort of an underlying kind of current where we can kind of jump into it. and if we're if we're present well we're able to see actually what pulls us in and when we do that you become more profitable i've never i've never sought to make money in my life i've never tried to make money i've never said i'm going to do a business to make money i'm going to do this to make money i'm doing what i'm doing because i feel like it's critical for for myself and for the people who i i care about and for the population at large it's like i just can't help myself.

59:05Dr. Mark Hyman:So I think when you do that and you have a mission and you're, you're driven, you know, then it's not about the money.

59:12Hala Taha:Love it. And Mark, where can everybody learn more about you and everything that you do? I know you're so easily found, but where do you want to point people to?

59:18Dr. Mark Hyman:Well, you go to drhyman.com. If you want to try the 10 day detox, you'd go to drhyman.com. You'll find it there, but just go to 10 day detox diet. I'm on social media, Dr. Mark Hyman, and I have a podcast, the Dr. Hyman show top 200 podcasts out there. So it's doing well.

59:33Hala Taha:Awesome. Cool. thank you so much for joining us on Young and Profiting Podcast.

59:37Dr. Mark Hyman:My pleasure. My pleasure.

59:41Hala Taha:Hey, App Fam, we're about to launch something that might be my favorite thing we've ever done on the podcast, a brand new series called How We Profit. Now, I've been doing Young and Profiting Podcast for eight years, and my listeners are successful. We are real entrepreneurs with real businesses, and a lot of you guys are crushing it behind the scenes. You may not be super famous, You may not be a billionaire yet, but you've got a business that you've learned how to scale. And we want to hear from you. One of the best ways to learn as an entrepreneur is from your peers. And I found it super helpful to be in these peer entrepreneurship groups and learn from other entrepreneurs who are at my level, but just in a different industry.

1:00:21Hala Taha:So that's what I want to bring to this podcast. I want this to be our own peer group, but on the podcast. And so I'm going to be interviewing people who are making anywhere from$500 ,000 to$10 million a year. They're not super famous. They're not the typical billionaires that are on my show. These are real entrepreneurs who are crushing it behind the scenes, and we're going to uncover what they do to sell, how they get their customers, what their profit margin looks like, how they market, and so much more. If this sounds like you and you want to be featured on Young and Profiting podcast for our How We Profit series, just head to youngandprofiting.com slash apply and share your story.

1:00:56Hala Taha:Let me know why you think you should be featured on the show. Again, that's youngandprofiting.com slash apply. And who knows, maybe you'll be our next guest on Young and Profiting Podcast.

From the publisher

Dr. Mark Hyman’s health broke down in his thirties when chronic fatigue syndrome and heavy metal toxicity left him struggling to function. Conventional medicine, the very system he was trained in, had no real answers for him. Forced to search deeper, he discovered functional medicine, used it for self-healing, and later reversed his biological age by more than two decades. In this episode, Dr. Mark shares how entrepreneurs can take control of their health, slow aging, and use small daily habits to boost performance and live a longer, more fulfilling life. 

In this episode, Hala and Dr. Mark will discuss: 

(00:00) Introduction

(01:45) The Science of Healthy Aging and Longevity

(07:09) How Functional Medicine Optimizes Health

(12:51) Biohacking vs. Functional Medicine Science

(15:34) How to Reverse Biological Aging

(20:12) The Role of Diet, Sleep, and Toxins in Aging

(28:15) Living Longer With Purpose and Meaning

(30:19) Navigating Modern Food Challenges

(36:08) Why Your Social Circle Matters for Longevity

(38:45) Diet and Exercise for Healthy Aging

(41:39) Practical Wellness Strategies for Entrepreneurs 

Dr. Mark Hyman is a practicing family physician, bestselling author, educator, and advocate in the field of functional medicine. He is the co-founder and Chief Medical Officer of Function Health, a personalized health platform that helps people understand and optimize their biomarkers. Dr. Mark is also the founder of the UltraWellness Center and the Cleveland Clinic Center for Functional Medicine. Through his work, he teaches people how to address the root causes of disease and build lasting wellness. 

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Resources Mentioned:

Dr. Mark’s Website: drhyman.com 

Dr. Mark’s Book, Young Forever: bit.ly/YoungForeverBook 

Dr. Mark’s Podcast, The Dr. Hyman Show: bit.ly/DrHymanShow  

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YouTube - youtube.com/c/YoungandProfiting

Newsletter - youngandprofiting.co/newsletter 

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Social + Podcast Services: yapmedia.com

Transcripts - youngandprofiting.com/episodes-new 

Entrepreneurship, Entrepreneurship Podcast, Business, Business Podcast, Self Improvement, Self-Improvement, Personal Development, Starting a Business, Strategy, Investing, Sales, Selling, Psychology, Productivity, Entrepreneurs, AI, Artificial Intelligence, Technology, Marketing, Negotiation, Money, Finance, Side Hustle, Startup, Mental Health, Career, Leadership, Mindset, Health, Growth Mindset, Motivation, Manifestation, Brain Health, Life Balance, Positivity, Happiness

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