

3 episodes
by Biotech 2050 · English
Biotech2050 Podcast is a think tank chronicling the disruptions changing the biotech industry over the next 50 years.




Robert Plenge (BMS EVP & Chief Research Officer) discusses how drug discovery fails, why “causal human biology” matters, and how to avoid “molex trap”/target herding by rewarding innovation.
24 Sep 2026 · 46m · 19 chapters
Nello Mainolfi (Chimera Therapeutics) discusses his career pivot from chemistry to biotech, how Chimera was founded in 2015–2016 to build targeted protein degradation, and why the company shifted…
16 Sep 2026 · 39m · 13 chapters
AI’s next era in drug discovery—how the field evolved from early computational/representation approaches (e.g., AlphaFold) to AI systems that increasingly run parts of the experimental loop,…
3 Aug 2026 · 48m · 20 chapters