Gut Health & Sex Connection: Anxiety, Sex Life & Health Risk | Anant Agarwal | FO445 Raj Shamani

0:00If you don't feel like a gut-brain sex connection, If you're not feeling horny everyday, then there's something wrong. Why would you say that? The better gut system you'll have, the more testosterone you'll have, the more dopamine you'll have, and the better brainwave sleep cycle recovery cycle you'll have. 90 % of people are wrong breathing. Right. Where do you lose fat from? It's out of breath. What's the matter? If you're not breathing correctly, you're not losing fat correctly. Most people are mouth breathing. When you breathe from mouth, you're hurting your gut. 90 % of mouth breathers are dropped.

0:32In today's episode, we are Anand Agarwal, a clinical research scientist and health consultant who is an expert of the body, mind and overall well-being. We have talked about health lifestyle, mindful habits and energy and confidence in which we naturally boost. What is the best way to do with which you can take? I was 155 kg and it took me 10 years to take care of which I was here. What did I do? We changed our food and we moved more. We take a protein shake in the morning. I made a protein aata. Tell us what. Pure pea protein. 300 gram. 300 gram satto. 300 gram basin. And 100 gram. Meaning a couple of aata.

1:10If you take it 40-50 gram aata and make a roti, it's 20 gram of protein. Is it safe for the weight loss? Is it safe for the osampic? If you give right people, it's 100 % safe. This should be used for obese people. Is there some new sort of drug which helps in diabetes? If you want to remove your blood from your blood, So what is the first logical? Eat less carbohydrates. Second, if insulin is not a fault, then add it from the inside. Third, what is muscle weight? What is obese according to you? In India, there are most obese patients. In India, there are also fat fat. If 100 people have heart attacks, then there are 40-45 fat fat.

1:43Are there new technologies or something which is coming which help people sleep better? If you take normal melatonin, you will fall deeper sleep. Do you think there are new technologies in smoking? Which you can quit smoking? There are some drugs which have been used for addiction like Tell me one thing, which all Indians are wrong. I think...

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2:25Weight loss. One of the biggest topics in the world. Patla on a technology. Technology is so far. In the world, I don't know where there are trials. What is the most, what is the best way, the latest, the fastest, no side effect, the best way to get you. Because Motapa is one of the biggest diseases in the world right now. And India is the capital. America is a big, even more than India. Globally, everyone has to get to get to. on how can you change? I think if you talk about without side effects, if done correctly, muscle building. There's no other way. This is a slow way. I think fast in fast way, without side effects, there's no way to change.

3:13Without side effects, without going through pain or without going through a tremendous amount of emotional suffering, if you tell. There's no way to change. Because you weight to come do you mind how to change you can I was 155 kgs and it took me 10 years of up down circles which I can come here 155 kgs 155 kgs and I have a lot ups and downs and I will explain that I will also say fat cell hyperplasia for example when you are 10 % big then imagine that water balloon is increasing Water balloon is increasing. Right? But water balloon in the water balloon when you increase fat when you increase fat.

3:56So you need to create more fat cells. So when you get more overweight 10-15 % than you get more overweight than you get the number of storage units increase. So if you think that you have 100 it can be inherently I have 1 ,000 ,000. For example because I was that fat. So when I gain fat I have to do 10 times more hard work than you have to do. For me to maintain the same level of weight that you would have to. Oh. because my storage units are more. When I increase my fat, you will increase every place. So if my 3 kg of fat is增加, you will increase it immediately because there are so many storage units available.

4:30So the best way to answer your question is muscle building. And if you say something quickly, I mean, to a certain extent, I would say now an emerald laser is coming to which you can do 2-3 inch spot reduction without much side effect. But I mean, again, I am probably 50 % right. but tell me 150 kgs as a family you have lost what did you do we changed our food we changed our food and we moved more we take protein shakes and we have fruits with it like the pair I have made a protein atta like protein powder sattu basin in that one in a routine 20 gram protein if you are a vegetarian you will get 40 gram protein if you apply that formula apply basically pea protein pure pea protein 300 gram 300 gram 300 gram basin and 100 gram meaning you can give some rice flour just as a bonding agent if you take around 40-50 gram aata and make a roti make a roti then it's 20 gram protein so those people can't eat protein shake in 2 roti 40 gram almost double protein shake got like pretty intense proteins.

5:48Protein if you take so much, then it gets digested? It's a myth. Look, 1 gram of per kg body weight protein which is the requirement that's the minimum that is required. If you read any journal then 2.2 is for weight loss. If you take twice the amount of protein which you talk about excess protein, actually we all have the imagination from bodybuilders. They had 4-5 times high protein which had Atkins diet or which had fat diets. they should take so much protein that it was bad for them you can't eat much protein as much as required but if we double even do it then don't you think body digest no it's absolutely not true there are more gut problems that's why when you start to take proteins I think it is important just like any medicine or anything to titrate slowly I don't say 100 grams of protein if you already eat 20 eat, we say first, 30 let your body get used to it let your body build some muscles, let your body move more, that protein energy requirement you take uptake, after 30-40 40-50, 50-60 I've been having 150 grams of protein I have no issues at all, but I'm saying this is my personal example, but this is something we do with our patients also, we don't say that you directly shock yourself then you will have gut problems but if you will do it slowly, because Because protein may the only important thing is ki aap ka toxicity level come on and clean protein on.

7:19Because protein is a requirement of the day. There is no doubt about it. Aap jitna protein looge, aap utna satiate hoge, aapka utna GLP-1 banega, jho olympic ka kham hai, and aapka utna hi muscle mass banega, and that is the only solution to everything. Aging kya hai? Loss of muscle. Aap jib age karte ho, aapke skin kiyo jhul jate hai? Loss of muscle. Aapka body kiyo sag hote hai? Loss of muscle. everything is a loss of muscle if you define full aging in one sentence because I am an anti-aging scientist we ask 3 questions as we age does this reduce with time? second if I put this thing in the middle will my lifespan increase?

7:59if I decrease it will my lifespan decrease? and the top answer is the protein osampic protein mean? osampic is a protein molecule okay explain actually before we even go there first background people who have to lose weight loss around the world now they are calling a new type of magic drug magic pill which is they are using a drug called GLP-1 and that is GLP-1 is an Olympic a company a type of brand which is used people say it like we technically pain killer nice use use weight loss drug osampic name now tell us the weight loss is safe or not I think right people safe I think who is who is because the best thing is in India not available people from black markets they have in India tablet form available which is ribalysis 3 mg 7 mg 14 mg in India in India weight loss not in India weight loss के लिए इंडिया में सिर्फ मोंजारो अवेलिबल है जिस्ट एक clarity factor के साब से जहां तक safety का सवाल है I would say कि अगर right logo को आप देंगे तो 100 % safe है What do you mean by right logo?

9:21जो लोग को ozampic requirement है अब उसको समझाने के लिए we have to go to GLP-1 GLP-1 क्या होता है GLP-1 is a basically is a peptide hormone protein hormone which makes gut lining this was in 1980 when it was discovered by a gila monster where a venomous lizard is where they know that the gut lining which is GLP-1 which is technically 90 seconds which is dissolved if you make a native picture and make a natural production is always a result many people don't know that GLP-1 is also a brainstem it is the signaling between your gut and your brain. When you eat food, your stomach is so big. Your stomach is so big.

10:10When you eat stomach, your gut lining is here. You start to make GLP-1 and your brain is so big. And after that, you make food. People say that GLP-1 which we do exogenously. Right? Which we do. That GLP-1 that is GLP-1 to keep a long time which is because you have more insulin produced so your sugar quickly dissipates and your body doesn't have fat and your stomach is very empty which you have a feeling of fullness right now problem is that this should be used for obese people because their gut-brain signaling is over their gut-brain they don't know but how much time it is if you start or take a Zempic or tablets how much time can people start to change?

11:05I mean, as a healthy weight loss if you don't have to sag your skin or not have to change your face it is approximately we would suggest more than 2-3 kgs or 4 kgs per month we don't like it to reduce more than that but again it is very varied that what happens on which and how much happens in any case, GLP ones do not work you would be surprised if you could do it you would be surprised why not do it it would not react it would be like pharmacogenomic profile that it would not work but if you want to do weight loss and work which is very small then 2-4 kg per month reduce easily or Zempick or something else I mean it's your luck paper you can do 2-3-4 kg or 10 kg or 3-4 kg or 15 kg or 40 kg or 40 kg But if you look at the clinical trial, if you look at the pioneer trials, then overall, with your ribelitis, which is available in the tablet form in India, you will have a 10-12 % body weight.

12:10But, as you said in the beginning, that it's a magic pill. Here, I would disagree. It's not a magic pill. It's not a magic pill without exercise and healthy eating. It won't be any work. Oh. So, it's not like, I'll keep my same lifestyle. I'll keep my own health. I'll keep my own health. nothing like that so if someone takes it and thinks that magically 4-5 kilos per month will be reduced and he takes it he doesn't train he doesn't take weights he doesn't eat clean what will happen ultimately every thing is your habits I would argue that if you leave the gym 6 months that your weight is life long maintained if you leave a good food then what will happen that your weight will be there the same thing which people's biggest complaint is that after my weight has increased.

13:00Yes, increased. If you don't have a habit, what do you do with the Ozympic? You are trying to give yourself a victory to make good habits. And then if you have started this, 10-15 kilos, and then you have stopped? If you have habits okay, there is no problem. If you have 1000 calories, if you have 1000 calories, you should have 2500 calories. and you have made a habit, I have 2000 calories or 2200 calories if you have 2200 calories then why weight will be bigger? The problem is that if you go back to 3000 calories, because ultimately, there is a basic thermodynamics, if you have calorie deficit, you have workout, your hormones, your testosterone, your estrogen, your progesterone all right?

13:52Because people say brain, gut, access I say brain gut sex access if you are not feeling horny everyday then there is something wrong why would you say that? because your entire brain gut access travels it also travels to your sex hormones if you are not motivated in life like we have a brain sleep cycle I wish I had a board I would draw you and see but there you go it's just a general cycle it's just a general cycle you think you have to sleep at 10am

14:32and these are the brain hormone cycles you have to sleep at 4 main brain hormones now when you sleep at night which hormone you have to be melatonin which people have to be supplemented in your brain naturally when you have to do it you will become melatonin then you go in a deep sleep wave now you are a deep sleep wave 1 then you are looking at a sleep rapid eye movement cycle REM then you are going to a deep sleep like deep sleep 2 and then you are going to a deep sleep REM 2 then you are going to a small deep sleep and then you are going to a sun from that sun you will become cortisol which is stress hormone that stress hormone you will be able to take it like a morning so you will take it so you will take it cortisol will be what will be dopamine do you know what dopamine is?

15:38will you listen? tell me dopamine is not a pleasure hormone dopamine is a motivation hormone it's an excitement hormone it's a motivation hormone if I see this brand if I give the Rajshamani just figure out if I just figure out I identify this as Rajshamani I will get excited that is motivation that is dopamine not meeting you meeting you is the adrenaline his cousin who is on the kidney so the more dopamine you have the more energy you have if you are motivated I want to do 5 podcasts in a day I want to do three podcasts in a day. You're very highly motivated and the more energy you're producing.

16:23Right? What happens with age? As we age, our dopamine starts lowering. Why? When you want to have the hottest girl trend, you want to have all the money in the world. We have

16:41uninformed optimism. Right? Uninformed. There's a business cycle. from uninformed optimism to informed optimism so you have uninformed optimism you're full of dopamine you're full of energy i will marry the best girl i will have the best business and as you're responsible in life your life becomes about spirituality figuring out yourself you know things like that so what happens from that? your dopamine will slowly work what is zero dopamine? parkinson's what is zero dopamine? dementia what is zero dopamine? Alzheimer's. What is extremely high dopamine? Schizophrenia. These are peaks. Extremes.

17:22What we want to do is we want to crack you somewhere in the middle. As you age, we want to keep your dopamine at base levels. Not very high, not very low. Base levels. How do you keep on base levels? Which is the same. Dopamine is called adrenaline. It is called adrenaline. It is called for 8-9 hours. After that, you will see all the and athletes do perco skill training karte hai 3 se 5 that is when you make acetylcholine kya hotha hai ye bhi eek brain hormone hai this helps in learning okay like um eek nhs meyuk ka cab driver study tha like london me black cabs jo hoot hai like they are the most sophisticated drivers unko london ka nook and corner pata ho ache agar aapko nook and corner nahi pata hai to you are fail yeah upro license nahi to eek scientist ne unka brain scan ki hypothalamus ka unka joh hypothalamus increased in size.

18:16Memory. Hypothalamus. Memory is responsible for it. Forgetfulness. People think that it is for memory. But that's to discard the relevant things. Okay. And only keep the right things. So hypothalamus will increase when they find something relevant to keep. Okay. So they found a skill which is relevant. So as you age, I'm telling all my patients to learn a new skill. Especially to my 45-50 above patients who are all settled in life. Learn something outside your range. Make yourself uncomfortable. Right? And then your evening's your evening serotonin which is a wellness hormone becomes and that serotonin hormone which is gives you a feeling of well-being.

19:03That is when you relax. That is when you do everything. And that gets converted later into melatonin through various processes. This is your sleep-brain wave cycle. is cycle in this cycle you have to see where your car is it is like because this is all time oriented and light oriented or when evening comes when sunset then your dopamine and acetylcholine start to get converted into serotonin and then serotonin where the moon comes from sorry my drawing that gets converted into melatonin when you start seeing darkness but you were explaining gut brain sex connection so this is your brain hormone right Your brain, the dopamine levels are tied to your sex hormone.

19:47The amount of body you will optimize testosterone. Say as a man, if I say testosterone ranges from 300 to 900. Like if you're say someone who's 350, you will be obese. If you're say 900, and this is a simplistic example, the nuances to it, you will be Hrithik Rosh. I want you to not just correct your testosterone, I want you to optimize it. the more testosterone you'll have the more dopamine you'll have and the better brainwave, sleep cycle, recovery cycle you'll have the better gut system you'll have if your anxiety causes gut issues your testosterone also causes your gut issues because it is causing anxiety it is not a two-way street, it is a three-way street

20:30there are three layers of things that you have to change about yourself I keep telling my male patients you check your female hormones check kareyye. You have a libido from estrogen. It doesn't come from testosterone.

20:44People think it comes from testosterone. That's absolutely wrong. Testosterone just makes you more of who you are. Testosterone is like winning a jackpot. What you do with that money is either you gamble it away or you make figuring it out. You know? So, you get your estrogen checked. You will find most fat men have very high levels of estrogen. They don't even need TRT. they just need to block estrogen whoa this is you said three levels you said something so it's basically this is the brain you said something with anxiety like if you have anxiety you will have gut problems twisting right because your brain gut axis I'm saying if you have anxiety you will also have sexual problems if you have sexual problems you will have anxiety performance anxiety you will have like I can't have sex what's the point in life my partner doesn't want to have sex with me I will surprise you there are there is a stat which says in the urological associations 40 % of men above 40 have ED problems 50 % of men above 50 have ED problems 60 % of men above 60 have ED problems no way they lie to you if they say that they have not and why do they have it?

21:59why do they have it? testosterone values have dropped from around an average of 550-600 to I have seen this to 300-350 normal 30 year old people are taking TRTs the sale of TRT in India you find out I don't have an exact value it's increased by 40-50 % what is TRT? testosterone replacement therapy the sale of testosterone replacement therapy has gone up in India? testosterone replacement therapy is called testosterone the injection sale has gone up by 40-50 % in India because people can't have sex anymore. Because of their lifestyle they have ED. Yeah. Obesity. I have two questions on this. First is that now you said that it's a natural cycle, brain sleep cycle.

22:51It's a lot of light. Sun comes, sun goes down and it's a serotonin secrete then light, moon comes, melatonin comes, darkness. This is what the process is. We live under this light. lot of people who live in offices artificial lights it's bright so you go to the night 10am it's bright it's sunny do you think that the brain gives a signal 100 % I think light pollution I tell you like see you I mean these lights and you start with lights that is wrong I don't say right wrong I'm not going into the moralistic thing of it but if you health wise as you think I think you should always dim the lights in the evening you say warm light now do warm light and you see how different feeling will come because I didn't include breathing cycle 90 % people breathe incorrectly okay then tell light pollution and then tell breathing so in light pollution basically when you are exposed to too much light you are confusing your brain what day or night if I will light light will open your eyes will open why would you go open?

24:05You were in deep sleep you were in sleep because your brain instantaneously reacts to light so I'm going to cry my brain wrong signals I'm saying that you have to manage your time accordingly I'm saying that if you're 8, 9, 10, 10 shooting is going on, it's okay but you're 12 hours but when you're sleeping 1-2 hours before give yourself dim lights to darkness that's okay but you can't just complete completely make a utopian world that all your life means that it's like a ruler. I understand that I'm practically talking about that it's not practically possible. But you can give yourself one hour of dim lights and dark lights.

24:46You can remove your phone for one hour before sleep. I mean that's what you can do. You can see sunlight in the morning for 20 minutes. You can walk a little. So you can sing your heart and brain. You can see it in the evening when it's sunset. You can see it in yourself. Because because this is your earth, this is the sun, morning 10am, this is the sun, 12 noon and this is the sun around 4pm. When you are in the morning 10am, you are only a long wavelength here, the small wavelength is not able to reach the earth because you are in slant position. so here if you will get sunlight from 6am to 10am then you will not get UV rays if you do it then you will reach short wavelength because it is overhead again the same thing after 4pm so it will reach long wavelength which helps you in collagen production which helps you genuinely collagen production so you should always give yourself expose yourself go for a small walk 15 minutes in the morning go for a small walk in Bombay you have to stay 7-7 sunlight so you You mean after 4 pm, you go on a walk.

25:59You will see how your brain waves will start sinking with your sleep. Quality of sleep will improve. On this basis, we make a supplement protocol. Supplement protocol says that you have 5-HTP in serotonin to melatonin. You have magnesium. L-theanine. These all help to reach melatonin. So, melatonin is an end supplement. First, we try magnesium. Then, we try health-theanine. then try 5-HTP then if you don't work then melatonin so this is how we make the supplement protocol for your brain sleep then sex for which you can use supplements and if it is not working then you use testosterone again we people the usage of drugs it is only based on tighter value and it is only based on need it is not based on I want it so many people melatonin directly without even going through magnesium and infasty honestly I have tried melatonin personally and for me I did not do it personally because there are many people who take melatonin and go up to 3 hours which made me prove that I had no problem if my brain is making melatonin and now you give excess melatonin you go into deep sleep and you go into 2-3 hours you get up.

27:23Fresh. You will wake up fresh after 2-3 hours and we have seen this multiple patients. Like I would say 20-25 percent of the patients. So while it works on some people, but it will not work on a lot of people also. So if that happens to you, if you're the 20-25 percent, this is not a problem. Okay, then you said breathing. That maximum 90 % of people are wrong. Right. I will come to oral care but let's talk about breathing. this was light exposure if I talk about breathing right if you can do it right now 60 seconds how many times you breathe like just if you can calculate like 15 seconds what do you know I am more conscious about it now I don't even know do it do it let's check

28:37this is four and a half five five this means that you are doing around 20-22 breaths right now if you will see the real version of breathing. Where you mean when you are relaxed breathing, an ideal person who is an athlete and who is very healthy and fit should be breathing 6-8 breaths per minute. Meaning you should have done 1.5 breaths by now. Now if I change your 15 seconds right now to

29:08you will automatically feel relaxed. Try it. Try 6 seconds to make breath. You will automatically feel relaxed. That's basically because I'll tell you why I said breathing. Where do you lose fat from? Breath. Fat, sweat, urine, stool, I mean maybe a little bit. Fat is not out of your breath. Your carbon dioxide carries your fatty acids outside your mouth. If you're not breathing correctly, you're not losing fat correctly. You're breathing.

29:43I just did four breaths in 15 seconds. if you're breathing so fast, you're not inhaling oxygen properly, not exhaling carbon dioxide properly. You're not striking the right balance. I need you to relax. Your cortisol gets relaxed. Your insulin gets relaxed. There are many things. So what should we do? We suggest box breathing. Box breathing is inhale, pause, exhale, pause. 4-4-4-4? You can do it up to 10 also. Okay. Like, slowly you increase. Yoga nidra is something I religiously follow. I always do yoga nidra before. like that's very important for weight loss you'll automatically feel relaxed your brain will feel relaxed so breathing, sexual health, gut health and my oral health because mouth breathing most people do mouth breathing your mouth opens in a time your nose has filters when you breathe from your neck you're taking clean air when you breathe from your mouth you're dry and you're dry and you're dry you are doing 90 % mouth breathers of the gut problems that's why today the trend is coming although I don't like it but if it works for them so when you are doing mouth breathing then you have to do oral care there is a brand called Perfora I feel so bad for them because they cannot market what they stand out for they use nano hydroxy appetite which you have to bind right better than in my opinion but they cannot brand it because people will not understand that if a ad is released that we use nano hydroxy appetite which people do and write but they will not come to understand what does that do?

31:28like before fluoride used fluoride your mouth is always in the process of decay and in the process of reconstruction always you should be eating or not eating whatever you have the more oxygen you take the more bacteria you take you keep your cavities you need to keep your cavities so to stop it you need 2-3 elements such as nano hydroxy apetite xylitol or xylitol or bit that was to protect from that bacteria but again people don't understand marketing but the intention was that it has all those elements like personally why don't you tell us about it maybe they think that consumer I will breach the consumer but your xylitol your nano hydroxy appetite your non-alcoholic mouthwash if there is an alcoholic mouthwash please throw it away it is only supposed to be used when you have an ulcer or if you have a proper infection in your gums it is not supposed to be used please throw it away far away from your building so what will it be for oral health care what will happen if you keep your mouth clean then again your mouth will open too, you will still have better oral care, you will not have bad breath your gut will not have bad breath so everything has to sink this will also help you sleep better but should you breathe out from your mouth?

32:54yes, it depends see now again breathing is a because we are human beings and we do nuanced things so when you are working out, no problem you can breathe out from your mouth but when you are not working out like again when I say that you have to do 6 to 8 breaths that is when you are addressed that is where you want to get to like I have got to 13, 14 I should do 25, 27 I'm a very anxious person I got to 13, 14 because I consciously keep because I'm talking to people so I'm going to do it but I want to get to maybe 6, 8, 10 I don't know so when you have this whole thing when you have a link after that we get your medical health and correction and we see what can we do at the lowest dose what is the function of medicine which people understand correctly is that our intention is to start from zero dose to get you the maximum output then we will apply one then we will apply two that is the correct way of medicine direct two people on their own will start from 14 and say we got side effects yeah that is We start with chemistry, direct and then start.

34:10Look, that regulatory aspect is so big. Also as humans, a lot of people want quick fixes. So if we know that the most powerful things available is, we just go and take powerful. We don't have that patience to actually go build it. I think a lot of it is to blame it to us. I think mindset should change from school. Like I think health sciences, nutritional sciences, should be introduced in school. For sure. like health sciences in the sense that you should understand yourself what you need to test your time through how do you monitor your health like things like this should be introduced in school and I think they will eventually because I don't think formal education exists in this case I don't think this is exciting we talk about weight loss drugs I saw a real by you that in the future in the future there is such a drug that you have to do with weight loss and muscle building also will be done.