RE-RUN - Menopause Q & A with Dr. Jessica Shepherd: Expert Advice on Symptoms, Treatments & Wellness

3 Jul 2025 · 1 h 15 min · 32 chapters

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In short

Menopause Q&A covering perimenopause “rollercoaster” hormone fluctuations; hormone therapy vs birth control pills; sleep and progesterone; causes of postmenopausal bleeding; bladder changes; mood swings on cyclic estrogen; progesterone cream options; key menopause-related lab biomarkers; exercise and Hashimoto’s; duration of HRT; bone health (osteopenia, DEXA scans); whether to start HRT without symptoms; visceral fat and weight changes.

Guests

Dr. Jessica Shepherd (chief medical officer at HERS; board-certified OBGYN; women’s health/sexual wellness/menopausal expert; founder of Synctom Med and Wellness; author of Generation M: Living Well in Perimenopause and Menopause). Interviewer hosts: Haley and Laura (The Body Pod). No other guests appear in the Q&A segment.

Key claims (notable examples)

  • Perimenopause symptoms can be driven by fluctuating estrogen/progesterone; OCPs may help symptoms but don’t replace HRT and pregnancy prevention matters.
  • For sleep: natural micronized progesterone (not synthetic progestin) may help; magnesium suggested.
  • Postmenopausal bleeding (after 12 months without a period) requires prompt OB-GYN evaluation; vaginal estrogen can also cause bleeding and still needs evaluation.
  • Bladder capacity decreases with estrogen; pelvic floor training is often overlooked.
  • Mood swings may persist on cyclic estrogen; switching to continuous dosing may stabilize levels.
  • If uterus is present, estrogen requires progesterone to protect endometrium.
  • Biomarkers discussed: estrogen/progesterone/testosterone, FSH/LH, thyroid panel, lipid profile, hemoglobin A1c, optional EKG, and ApoB.
  • Bone: best non-drug intervention is resistance/weight training; HRT and exercise work via different mechanisms; DEXA radiation is low and can be used earlier than age 65.
  • HRT can be considered for quality-of-life/longevity even without classic symptoms.
  • Visceral fat increases with age/insulin resistance and estrogen/testosterone decline; HRT may help but weight loss still depends on broader factors.

Written by AI. May contain mistakes. Listen to the episode to check what was said.

Chapters

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Dr. Jessica Shepherd's Background

1:44 to 2:38

Get to know Dr. Jessica Shepherd and her expertise in women's health and menopause.

“Hey everyone, this is Haley and I'm Laura And welcome to The Body Pod.”

Common Questions on Menopause

2:38 to 3:52

Dr. Shepherd addresses common menopause symptoms and treatments.

“I mean, we have like all of these questions and we gave away the Generation M book yesterday.”

Hormone Therapy vs. Birth Control

3:52 to 7:58

Discussion on the differences between hormone therapy and low estrogen birth control for perimenopausal women.

“I also heard this is controversial because the pill is not hormone therapy and women may get better results from hormone therapy than just the pill.”

Improving Sleep During Perimenopause

7:58 to 11:45

Dr. Shepherd explains the impact of hormonal changes on sleep and offers solutions.

“So for a perimenopausal woman who is already prone to waking up around two to 3 a.m.”

Postmenopausal Bleeding Concerns

11:45 to 14:00

Understanding postmenopausal bleeding and when to see a doctor.

“I try to like turn off the phone and, you know, it's just a doozy.”

Understanding Post-Menopausal Bleeding

14:00 to 15:30

Learn about the causes and importance of addressing post-menopausal bleeding.

“So both of them are still very important, but two different reasons why you might be have bleeding.”

Bladder Changes During Perimenopause

15:30 to 17:40

Explore how perimenopause affects bladder capacity and urinary frequency.

“It doesn't necessarily mean that you have to come off of your HRT or your vaginal source of estrogen.”

Hormone Replacement Therapy Insights

17:40 to 21:10

Discover the nuances of hormone replacement therapy and its effects on mood.

“The other thing that I will say is we don't typically work out our pelvis, right?”

Progesterone Creams: Benefits and Recommendations

21:10 to 24:30

Get insights on progesterone cream options for women, especially post-menopause.

“I would say at the end of all of this is for everyone on here to realize that however they're taking it or if they're not taking it or if there's always options.”

Monitoring Health Post-Menopause

24:30 to 28:00

Learn about key biomarkers to monitor for active postmenopausal health.

“So when, yeah, when patients come into my office, you know, to me, the menopause transition is much more than just the reproductive hormone portion of it.”
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Understanding Cardiovascular Health in Menopause

28:00 to 29:59

Learn about the importance of cardiovascular health for women during menopause.

“It can be kind of increasing the plaque that forms in your vessels, which may contribute to cardiovascular disease.”

Hormone Replacement Therapy and Perimenopause

30:00 to 30:59

Explore the role of hormone replacement therapy during perimenopause.

“Do you ever recommend hormone replacement for women?”

Exercise and Bone Health

31:00 to 34:04

Discuss the impact of exercise and hormone therapy on bone health.

“Hormone replacement therapy has been proven from the estrogen portion to improve bone mineral density.”

Managing Hashimoto's and Exercise

34:05 to 37:31

Get insights on managing Hashimoto's through diet and exercise.

“of what you could get if you were doing those other things.”

Hormone Therapy for Long-Term Health

37:32 to 41:11

Understand the benefits and considerations of long-term hormone therapy.

“So for someone that is on HRT, they're 55.”

Osteopenia and Hormone Therapy

41:12 to 42:04

Learn about the role of hormone therapy in preventing bone loss in osteopenia.

“So what do you recommend to your patients with osteopenia, estrogen, HRT, as a prevention for further bone protection or bone loss?”

The Importance of Strength Training for Bone Health

42:04 to 45:22

Learn how strength training and MHT work together to improve bone density.

“And also with HRT for all of these, that's never going to replace strength training.”

Understanding DEXA Scans and Radiation Exposure

45:22 to 48:20

Discover the safety of DEXA scans and recommendations for frequency.

“but it really requires a lot of exposure to radiation for someone to say, oh my gosh, I got a cancer from actual, right?”

Hormone Replacement Therapy: When to Consider It

48:20 to 50:40

Explore whether perimenopausal women should start HRT even without symptoms.

“Would you recommend somebody going on HRT that's not having any symptoms, still has a period and perimenopause, but like doesn't have any headaches?”

Visceral Fat and Its Impact on Health

50:40 to 56:00

Learn about visceral fat and strategies for fat loss during perimenopause.

“If they choose that route in the future, should I check, should I consider checking my hormones at this point anyway, if I, or wait until I have further symptoms.”

Understanding Insulin Resistance and Weight Management

56:00 to 57:20

Learn about insulin resistance, its effects on weight gain during menopause, and the importance of muscle building.

“It's really just this thing that's happening internally.”

Libido and Natural Supplements for Menopausal Women

57:20 to 58:40

Explore ways to enhance libido and sexual health naturally during menopause.

“I can't wait to watch all of your stories.”

Hormone Replacement Therapy and Its Risks

58:40 to 1:01:00

Discuss the safety of various hormone therapies and their relation to breast cancer and cardiovascular health.

“What do we know about safety of oral micronized progesterone compared to progestin?”

The Role of Estrogen for Skin and Bone Health

1:01:00 to 1:03:20

Learn about the benefits of estrogen in skincare and its importance for bone density.

“So yes, as an aptogen, that's completely fine to take.”

Impact of Weight on Perimenopausal Symptoms

1:03:20 to 1:05:20

Understand the correlation between weight gain and worsening symptoms during perimenopause.

“You don't need to know about that, but everyone kind of has a score of where they are.”

Managing Vaginal Dryness and Sexual Health

1:05:20 to 1:07:20

Explore various treatments for vaginal dryness and enhancing sexual wellness during menopause.

“If you wanted to look it up, it's called Glycanage, G-L-Y-C-A-N-A-G-E.”

Birth Control vs HRT in Managing Heavy Periods

1:07:20 to 1:09:50

Discuss the considerations for switching from birth control to hormone replacement therapy for heavy periods.

“I mean, thank goodness for this day and age, right?”

Hormone Therapy for Urinary Concerns

1:09:50 to 1:10:02

Learn about the benefits of hormone therapy for managing urinary issues in menopausal women.

“It helps with the bleeding portion of someone who's perimenopausal and also provides birth control while you can still address considering MHT in the perimenopausal phase if you wanted to.”

Hormone Therapy and Urinary Health

1:10:02 to 1:11:34

Learn how hormone replacement therapy can help manage urinary issues during menopause.

“What are your thoughts about when this person entered menopause, she started experiencing recurring UTIs and urgency and continence.”

Restoring Libido Post-Menopause

1:11:34 to 1:12:38

Discover the potential benefits of testosterone therapy for women post-menopause.

“So protect your urethra, consider vaginal estrogen as both helping with symptoms and also being preventative for later on in life.”

Understanding Fibroids and Their Impact

1:12:38 to 1:14:18

Explore how fibroids affect women's health and the importance of monitoring them.

“I hope this is considered general enough.”

Gratitude and Acknowledgments

1:14:18 to 1:14:46

Hear expressions of appreciation towards Dr. Jessica Shepherd for her expertise.

“Jessica, I adore you and I'm so grateful and I'm so sorry we kept you a few minutes over.”
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Transcript

Automatic transcript. May contain errors.

0:00You've stuck to your calorie budget, you've done every workout, and the scale hasn't moved in weeks. That's exactly why I created Shred Happens, my most popular six-week challenge completed by thousands of women over the past three years. It's a proven system designed to tackle stubborn fat gain and muscle loss while still allowing for satisfying meals and flexible workouts that fit your life. You'll get a private accountability group, live expert coaching, and this year's incredible shred experts, Mickey Williden, Bill Campbell, Dr. Kelly Kasperson, and special bonus guest, Alyssa Olenek. Thousands of women in my community have achieved visible fat loss and muscle gain without starvation diets or endless cardio.

0:43Shred Happens opens just twice a year and VIP registration opens October 6th. Click the link in the show notes to get on the list and be first in line. Hey, everyone. Today, we are doing some reruns for the month of July with really popular episodes that we've had in the past two years. So in today's episode, I get to interview and do a quick Q &A with my favorite of all time, Dr. Jessica Shepard. And she is here to answer the most common questions about menopause symptoms, treatments, and how to manage the physical and emotional changes during this stage of life. From hot flashes and mood swings to hormonal therapy and wellness tips, Dr.

1:26Shepard shares her expert advice on navigating menopause with confidence and maintaining overall well-being. Whether you're currently going through menopause or preparing for it, this episode provides valuable insights and practical tips to help you feel your best. I hope you enjoy this rerun with Dr. Jessica Shepard. Hey everyone, this is Haley and I'm Laura And welcome to The Body Pod.

1:56Welcome back to The Body Pod, everyone. Today, I have the pleasure of interviewing Dr. Jessica Shepard, who is a chief medical officer at HERS. She is a board-certified OBGYN, a women's health, sexual wellness, and menopausal expert, and the founder of Synctom Med and Wellness, as well as the author of Generation M, Living Well in Perimenopause and Menopause. So today, you get to join me while I have a quick Q &A rapid-fire session on all things menopause. Enjoy.

2:37Everyone is so excited for you. I mean, we have like all of these questions and we gave away the Generation M book yesterday. And so super excited about that. I've loved seeing the progress of Generation M because you have just been like killing it on the Today Show, Good Morning America, like all of these, all of these things, which is just so incredible. So thank you. Thank you. thank you for joining us. You know, you're my absolute favorite of all time. You're my favorite. And we absolutely like, I don't know why we aren't meeting, but we're meeting this year. Yes. Oh yeah. For the end of the year.

3:16Absolutely. Okay. I'm going to get started on these so we can get you in and off to packing wherever you're going tomorrow. Where are you going tomorrow? I'm going to Ibiza, Spain. were you just in italy too someone's got to go to these places and talk about menopause you know hey sign me up for the gig i mean i'm all i'm all for it so good thing that you're traveling it's like work slash really cool vacation place to go so i love it all right we're gonna get we're gonna get right into it so first question i have heard that doctors will prescribe low estrogen birth control to women in perimenopause when the woman has been suffering from some of the common perimenopause symptoms, poor sleep, mood change, low energy, brain fog, lack of libido.

4:09I also heard this is controversial because the pill is not hormone therapy and women may get better results from hormone therapy than just the pill. If blocking the sperm is not a concern, should women in peri with these symptoms be looking at hormone therapy instead of the low estrogen pill? oh i love this question i actually answered it yesterday so i was at eudaimonia uh over the weekend and we we i did three sessions just on hrt and that was exactly one of the uh questions that we got so i'm kind of gonna back it up until the perimenopausal phase and exactly what it is and why it's actually a little bit more confusing than the menopausal phase because during perimenopause is where you have this rollercoaster fluctuation of hormones.

4:58And with that fluctuation, you have estrogen that some days are really sky high, really low. And a lot of those fluctuations cause some of the symptoms that people start to have that we would typically categorize as menopausal symptoms. So hot flashes, night sweats, irritability, obviously of your decrease in your muscle mass that starts to occur from your mid thirties. But these symptoms usually are going to be infrequent or not as maybe severe. The problem becomes because you're still menstruating, whereas in menopause, you are not menstruating. You still have estrogen and progesterone, which means that if you're still cycling and have a menstruation, you have the ability to potentially still get pregnant.

5:42Now, is that likelihood high? No, it decreases as you go through your 40s, but there's still that likelihood. Now here comes the tricky part is that birth control, yes, it does have synthetic forms of estrogen and progesterone in it, but what's its job to prevent pregnancy? HRT is usually going to be more of a different form of estrogen and progesterone, but it's on a much lower level. So it does not prevent pregnancy. So that's why in the perimenopausal phase, it becomes a little bit confusing as could I take OCPs? Absolutely. You could. Does it take care of some of the symptoms that are what we call perimenopausal menopausal symptoms?

6:25Yes. But the tricky part becomes, do I stay on it throughout my 40s into when I might be the least likely to get pregnant or a menopausal? Or do I start HRT? So the way that I like to answer that question is if you're still having symptoms and for a smattering of other reasons, say you're not sexually active, say you really have infrequent periods. periods or you're down to maybe minimal periods and you're like my risk of getting pregnant is really low i would like to switch over to hrt to help with my symptoms and also booster my estrogen progesterone kind of um scaffolding which helps with longevity and bone and all of those other great things but there are a lot of people that are relatively younger maybe still have cycles regularly.

7:17I have 47 year olds, I have 52 year olds who have cycles regularly. And so to me, even though the likelihood is lower, they still are ovulating enough to a level to elicit a period, which means they're probably ovulating. So they're probably people that I'll be like, you know what, you can get benefit from both, but let's prevent pregnancy should maybe be prioritized than just looking at it from an HRT perspective. So the hormones in both of them are completely different and they do different things. So you do have to weigh where you are in the process, what you're looking for as an outcome, and then make a decision.

7:57Oh, that was the best answer of the night, right at the top. Actually, I don't know. I haven't read them all. I've read most of them. Okay. So for a perimenopausal woman who is already prone to waking up around two to 3 a.m. This is me. I didn't do this question, but this is me. But who definitely wakes up with hunger around 2 to 3 a.m. when in a calorie deficit? Do you anticipate that adding progesterone at night might be helpful for better sleep? Yes. So was the hunger part part of the question or just the sleep? I think they're saying that they also wake up if they're in a calorie deficit, it, but then they're waking up anyways, if they're not.

8:38Okay. So let's, let's address it as just a pure sleep question. And maybe if there is more clarity on the, the, uh, the hungry part, then I can address that. Um, but there's multiple reasons why we have change in our sleep during the perimenopausal phase into the menopausal phase. And then again, it has to do the fluctuations. So we'll go back to that rollercoaster ride that you're having where you don't have this great consistency in how your hormones are starting to show up. And so it happens, namely progesterone, which is, I like to call it our comfy hormone. It really like relaxes everything.

9:12It makes the GI relax. It makes your sphincters relax. Everything is just like so relaxed. So in addition to that is it really does help relax you from a sleep perspective. And so when we start to have actually a really significant drop in progesterone during the perimenopausal phase, that's when it starts to impact not only from the comfy perspective of what it does, but also our circadian rhythm, right? And so our circadian rhythm is ever so important when we think about what it provides as far as timeframes of when you're having certain, when your brain is regulated to sleep, being sleep versus awake.

9:54But then you're also having now this disruption in your progesterone, which is also impacting how you're able to relax in that, in that timeframe. So because of that fluctuation and decrease in progesterone, it is actually a good idea to consider progesterone. And when I say that it has to be not synthetic progestin, because that is the one that actually we don't like, because it does have increased risk of breast cancer in that use, but a natural progesterone, which you can get from a regular pharmacy. So that can be your micronized form of progesterone in either a dose of a hundred, 200, some people take a little bit higher, maybe 300, but we do see that because of that phase or that, that drop in the hormones, you're not going to have a quite as much as the sleep that you like.

10:41Now, the other thing that occurs too, is it impacts. So now you have estrogen starting to decrease, which doesn't take as much as a dive is progesterone throughout the perimenopausal phase. But because estrogen decreases, a lot of people then have night sweats because that's where we get a lot of our hot flashes and night sweats is because of the decrease in estrogen. But even if you don't notably have a night sweat, we have a lot of good data that shows that even if it's not visibly waking you up and you're sweating, that people actually do experience night sweats or hot flashes at night. But it's not the typical one, but it's still enough to wake them out of their sleep.

11:23So a good way to start, especially if someone's hesitant about going on HRT or the estrogen part of it, is actually just to start with a progesterone compound and also to start magnesium as well. Magnesium is a beautiful way for you to kind of get that regulation back with your sleep habits. So those are two good things that you can put into your routine when it comes to sleep. Oh, I'm getting on the progesterone because my sleep is not good. Yeah. And I do all the right things. I try to like turn off the phone and, you know, it's just a doozy. And so you're still getting kind of the awakening, right?

11:59Yes. Yeah. Every time. And then I'm just like, should I get up and work? No. 2.33. Don't do it. Eventually I go back to sleep, but it's a doozy. can you please give possible causes of postmenopausal bleeding and suggestions on how to stop it yeah postmenopausal bleeding is definitely one of those things as an ob-gyn that really concerns or alerts us okay it's something that when someone says that immediately we're like but why why are they bleeding if they've experienced menopause so menopause technically means you've gone 12 months consecutively without a cycle consecutively is important because some people will not have a period for 10 months and then they'll have a cycle.

12:45And I'm like, we have to start the clock again. So unless it's 12 months consecutively that you have not had a cycle, then that's menopause. Like that is the hallmark in the start. And thereafter, you should not ever have any more bleeding. So if you do have bleeding after that, it is really important that you talk to your OBGYN about that because we need to know why is your endometrial aligning causing bleeding if your ovaries are not giving off enough estrogen to cause a cycle so there should be no bleeding at all so it's very important that you talk to your doctor about that the caveat to that is that there is if someone is on actual hrt with a form of estrogen in it it may cause a bleed that is not a bleed of your of your uterus but the estrogen that you're on is causing the bleed.

13:38But it's also important to still talk to your doctor about it because then we can at least put into the equation while she is on HRT with estrogen component on it, could it be the estrogen that's eliciting this bleed? And we can figure out, you know, through ultrasound, we can see if it resolves on its own. We can decrease your level of estrogen if you're on HRT. But if you're not, then we definitely have to look into that as a reason of why. So both of them are still very important, but two different reasons why you might be have bleeding. End story is if you have bleeding after menopause, absolutely categorically do not hesitate and go see your OBGYN.

14:16Okay. Does the next question kind of piggybacks off of that? Can vaginal estrogen cause post-menopausal bleeding? Is that a reason? It can. And the reason is we have estrogen receptors all over our body. I think we do typecast it to just being in the pelvis, specifically the vagina, but we have it in our bone, our brain, our heart, our muscle. So because it's very sensitive, obviously within the pelvic region, especially the vagina, because that's what allowed the vagina to have secretions when we were younger in our kind of reproductive phase, you know, like think about it when you have a baby and baby gets all the way through the birth canal.

14:53And then when it comes out, it goes back down to size. So that's the flexibility and distensibility of the actual vagina, estrogen has a lot to do with that. So now when we lose our estrogen and our vagina doesn't have the ability to be distanced, it becomes more fragile. The tissue becomes more fragile. And now you start vaginal estrogen, the receptors are like, thank you. Thank you so much for pouring this estrogen into the area that we really do love. And it helps the vaginal tissue thrive. So if you have vaginal bleeding, after still another reason to go to your OBGYN and get it checked out.

15:30It doesn't necessarily mean that you have to come off of your HRT or your vaginal source of estrogen. We just want to make sure we are definitely providers or professionals that want to rule out worst case scenario. So we will always be like, what caused the bleeding? And if we can make sure that it's nothing that has to do with anything that we're concerned about, then we feel better and we can manage it that way. That's a great answer. Moving on to the bladder. How does the bladder change during perimenopause? I feel as though it is smaller. I need to go to the bathroom way more often and the amount isn't as much as I used to be able to hold.

16:07This is me all the time too. Not my question, but this is me. Yes, there is a lot in the pelvis that responds to estrogen And the bladder actually is a very beautiful part of the pelvis. A lot of times it's forgotten because it doesn't seem like it's part of the uterus, vagina and ovaries. But it really does have sensitivity to both progesterone and estrogen. But the same type of thing that I talked about in the vagina happens with the bladder. So as we start to age, it doesn't, you know, the distensibility and the capacity for it to hold urine is not as much. it obviously the sphincter so the part that closes when you're not urinating and then that opens when you do want to urinate it gets a little bit looser right so now you have incontinence issue with leaking because the door the stop cock is not there as well and then the other thing is that estrogen really has the ability to our control of the actual bladder so it's smaller It does not hold as much.

17:10And so if you think about during the night, a lot of times that's usually when, you know, your bladder usually will capacitate a lot more as you're in rest. And then when you get up, usually after maybe eight hours or however long you sleep, then you do have to use a bathroom. But if it can't go as big as it used to and hold as well as it used to, that again is why we start to have more issues with our bladder and having to have decreased time in the times between we need to urinate as we used to before. The other thing that I will say is we don't typically work out our pelvis, right? So when I think of a pelvic physical therapist, which helps us with our bladder and our control of our bladder, most women have never been taught how to do really good pelvic exercises to strengthen their pelvic bone.

18:00and so as we get older and this starts to happen we don't know how to kind of control it and keep it to do what we would like it to do and then on top of that think of what usually happens we have pregnancies uh then you know even whether it's c-section or vaginal delivery childbirth a lot plays a lot of like trauma on the bladder and so over time it just gets a little bit weaker and it is quite frankly, when, when I used to do a lot of surgery, it's, it's a kind of, um, lazy organ. It just likes to forget what it does. It's like, what were we doing again? I don't know. So it is a little lazy, but I will, I will give it some slack and that the estrogen makes it smaller.

18:44Okay. Good to know. So I am using estrogel for 12 days a month and a testosterone gel. I still get mood swings despite this routine. Is this something that can be changed with dose increases. So tell me how long they're on the estrogel. 12 days. Yes. Okay. So when we think of hormone replacement therapy, there are reasons why people can take it cyclic, which is exactly what you described taking 12 or 14 days, depending on how someone prescribes it, or you could just take it all the way through. So I'm going to answer the question is if they're perimenopausal and menopausal and the perimenopausal phase, because we're doing that whole kind of rollercoaster thing.

19:30Sometimes it is a little bit hard to figure out where your fluctuations are. And if you're not on estrogen for the other remaining days, what's happening during those days as well, you still may be having these fluctuations and that can be contributing to the actual, um, let's see, it can be contributing to the actual kind of frustration, irritability, because you don't know where you're controlling. It's still just kind of all over the place where it was a little bit more predictable earlier in our teens, 20s and 30s, because it followed the regimen, it followed the schedule. Now it's just like erratic all over the place.

20:06And then the other reason is that in a continuous fashion, sometimes it is better to try and convert to a continuous fashion, because then And whatever you're on, whatever dosage you're on can really be there to kind of buffer those fluctuations and keep the stability of the levels of hormones. So for someone who is taking a cyclic form of the HRT in the gel form, I think it's worth a try or a shot to maybe just do it continuously to see what the outcome is, because there's no harm in taking it continuously during cyclic. Like it's just how it was prescribed that maybe that was thought it, it could be done in that fashion.

20:48But I think a good way to test, you know, if you're going to have these kinds of dips is just to try a continuous form, obviously with the advice of your doctor and in what dose you're on and figuring that out and seeing if you can actually eliminate those moments and where you have the irritability. I mean, all of this, there's so many different options that you can use for this. I would say at the end of all of this is for everyone on here to realize that however they're taking it or if they're not taking it or if there's always options. Oh, I love that. Yeah. For postmenopausal women wanting to use progesterone cream alone, no estrogen for sleep benefits.

21:30What are the FDA approved options for progesterone cream that you would recommend discussing with our health care provider? Yeah, progesterone cream. So what we have in, I guess you could say in a pharmacy fashion and what pharmaceutical companies, usually they will be in a pill form. Now, for a cream, usually it is a bioidentical form. It could be compounded and so that you can actually titrate the amounts differently because it is compounded. What I would say is that because you're doing it in that fashion versus just estrogen alone, it is much safer. So I said this yesterday, every woman who decides if they want to take HRT, if you have a uterus, you must take progesterone if you're taking estrogen.

22:16If you don't have a uterus, that's the only time you have the luxury of saying, I would like to take estrogen alone. And the reason is, is because they balance each other out. and if you only take estrogen and have a uterus the lining in your uterus will build and build and build and it can potentially become endometrial cancer because progesterone is not there to equal it out and so progesterone however you can take alone without estrogen but progesterone and estrogen if estrogen is taken you must take progesterone if you have a uterus. So with the cream, there's usually going to be in a compounded version of how you take it.

22:57And it is very safe. I think it's like, I always say it's like one of the best ways to test HRT. If you're a little bit hesitant about it, it really is like the cutesy type of benign or friendly, you know, like for people who are just like, Oh, I don't know if I should do HRT. progesterone really is that one that you can try in a cream form and get that compounded as well and there's and there's different levels of it as well there's different dosages as well i hope i'm answering that question in the right way the other thing too is that i just as i'm thinking through the answer there are a lot of progesterone creams that you can get over the counter like if you go to like because it can it can be made with yams right so in my head i'm thinking that's where this question may have come from because there's ones that actually are the bioidentical forms of the hormones in your body which would be prescribed and then those that people can try and make from wild yams so that it can replicate to some degree what progesterone can do, but it will never be as strong as what something is compounded and made in an actual pharmacy or compounding pharmacy and actually made from a chemical form.

24:19So you may get relief from the ones over the counter, but there are some people who may try that and not get the relief they're looking for and may need to transition into more of a prescribed progesterone. Okay. What are the most important biomarkers for an active postmenopausal woman to monitor for maintaining health at this stage in life, which specific blood mark blood work markers, um, percent, uh, muscle mass or body fat percentage. Do you have any? Yeah. So when, yeah, when patients come into my office, you know, to me, the menopause transition is much more than just the reproductive hormone portion of it.

25:00That's obviously a big part of it because it's the ovaries that have declined in their ability to do what they do. And so we do have our estrogen and our progesterone that we can monitor through that as well as your testosterone. But you also have progesterone and testosterone that come from your adrenals, but most of your estrogen does come from your ovaries. So those three obviously are ones that we're going to look at. And then we'll look at the hormones that tell those ones to release, which would be your follicle stimulating hormone, which is your FSH, and then your luteinizing hormone. Are they as important?

25:31No, but they're good to include in those to kind of see where those are as well. I always look at thyroid and I look at a full panel of thyroid because hormones are chemical messengers and they like to talk to each other and tell it's a symphony. Everyone's telling everyone what to do and where to be and how to show up. And if you basically have a portion of the symphony, you know, that's playing bad notes and sounds horrible, everyone knows and everyone kinds of like is noticing that. So thyroid is, It's a small little gland in your neck, but it really does have a lot of responsibility. So full thyroid panel, in addition to the other ones I just said, I also look at your lipid panel.

26:14So because estrogen is decreasing over this timeframe, it actually triggers. Remember we said estrogen receptors are all over your body. So there are a lot of features that occur as you're starting to age with your lipids. And those start to increase and sometimes do some funny things as well. So a lipid profile is also very helpful to make sure you're not increasing some of your triglycerides or your total cholesterol to watch that as well. Another test that's also important is your hemoglobin A1c. Your hemoglobin A1c is a lab that we draw that helps us to tell if you're going towards a pre-diabetic or a diabetic stage.

26:56We know that as we age and estrogen starts to go down, our body starts to have more insulin resistance. And one good way to make sure that we're not becoming completely insulin resistant is to make sure that our sugar is not creeping up. And that is a better range than just taking a random sugar, which can be on a lab and testing over the last three months, what it's been looking like in your system. So hemoglobin A1C. I also recommend that women ask for maybe EKG to just see the functionality of their heart. It's such an easy way to just look at the functionality of your heart and what's going on.

27:34And then one more thing that I'll mention, it's called APOB, A-P-O and then a big B. And that is, again, a key factor in determining someone's risk in cardiovascular disease. And basically, it's a protein that kind of facilitates and transports lipids. So if you, again, have an issue with your APOB, that means that your lipids may not be getting to where they need to go to. It can be kind of increasing the plaque that forms in your vessels, which may contribute to cardiovascular disease. So, again, that's another one that can be included in a blood test to kind of help because number one killer of women is heart disease.

28:16A lot of times we think it's breast cancer or we think it's something else, but it's actually heart disease. So we really have to take care of our hearts, especially as we start to go through menopause. Perfect. So is it what is the difference between using combined pill, staying on it versus switching to MHT? Are the hormones the same? Oh, we talked about this. They're different. I'm 52 and have been on OCP since 18 and was planning to just stay on it until 55, then switch. but MHT is more appropriate. So really that you covered that of what we should do at the first. I would make a strong disclaimer for someone.

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29:01I, for me, typically this is personal over the age of 35, I birth control pills. I'm like, okay, how much longer do we have to stay on this? Can we find another way? Even if it's for birth control, I'll try to find other modalities of birth control. we did definitely so there's nothing wrong that was done we definitely have used birth control pills for decades as a form of mht we now are much better educated and understanding of the different types why it's needed what levels are needed for us to i think get more women off of birth control to me, typically the latest, maybe mid forties, early forties for me, even if I, if I can get them on another kind of birth control.

29:48Um, but at that age at 50, 52, 55, I would not wait till 55 to switch and just get off of it now and switch to MHT. Okay. Perfect. Do you ever recommend hormone replacement for women? Oh, in perimenopause. So at what age my testosterone is super low and my doctor recommended a testosterone supplement. Something had never something had never I'd never heard of before. A troch. Oh, yeah. So it's a trochee, trochee. It's basically like it looks like a pill, but you put it in your your gum and it dissolves. So you get what we call like sublingual release of whatever it is. I mean, anything can be in a trosh.

30:35It can be a medication. It can be a hormone. So ask the question again, because now I forgot. I just, oh, so they do you. Okay. Well, one, do you recommend HRT in perimenopause? And if so, what age? And then, um, her testosterone is super low, but her doctor recommended, uh, a testosterone trosh, something that she had never heard before. Okay. So back to the question about when to start, it kind of goes back to the question of the birth control control pill in when is that time that your perimenopause which is usually your 40s early 50s for some because they still may be menstruating is i need to sit and think about if i would like to stay on birth control if i'm very sexually active and there's a good possibility i could have a baby right because then that makes to me it prioritizes birth control over mht team i have frequent cycles in frequent cycles which again is going to go to is it likely for me to get pregnant or very very unlikely for me to get pregnant and i can transition over to hormone replacement therapy so those are like everyone's going to have a different answer choking um so it's important to know who you are and what you're looking for

32:03i'm gonna drink water yes drink drink some water i'll get to our next question we didn't do the trochi one oh okay let's get let's hit that first so testosterone is is fine to take as hrt i don't have a problem with taking it that way there's various ways to take it you could take it that way some some injection i'm not a fan of the injection you can do testosterone creams and then also testosterone palate so there's various ways yeah there's nothing wrong with that modality okay great moving on to what are your thoughts on merodyne live vibration plate for osteoporosis and or overall health can you spell that um m-a-r-o-d-y-n-e-l-i-v the vibration plate maybe just a vibration yes the vibe i'm doing really good on this so that really really what it is is is to create low density vibration to help with stability to help with flexibility would i say i wouldn't say it's bad but is it evidence-based as a form in a way to improve osteoporosis i would put it more in the cat in the category of a supplementary a supplementary way to improve bone mineral density ways that you're going to improve your bone health from a bone mineral density is resistance training so weight training and also increasing your protein intake and also HRT.

33:48Hormone replacement therapy has been proven from the estrogen portion to improve bone mineral density. So it's not like it's a bad thing, but maybe put it on the list of things in addition to the other thing that I mentioned, then making it maybe the only thing that you're doing, thinking it's going to just magnify your bone mineral density to the level of what you could get if you were doing those other things. Okay. I have Hashimoto's and wonder about all the conflicting information I read about whether or not to do high intensity exercises. I always think working at my best level is best. For example, lifting the heaviest, I can go with good form.

34:27What is optimal for people with autoimmune issues? Do you have a take on that? So that's a multi-layer question. I think when we think of Hashimoto's, right? So a lot of that has to do with it's autoimmune disease meaning that your actual thyroid is attacking its own organ right so the goal with that is to manage how to get the thyroid levels back into a normal range which sometimes may need medication which is okay but there are other ways that you can I guess facilitate the Hashimoto's and a lot of that actually can be with diet and then if you think about it, most women will have thyroid issues after the age of 40.

35:12And a lot of that has to do with starting with the fluctuations in their reproductive hormones, namely estrogen and testosterone. Remember you're talking about the symphony and so one is out of place. And so it causes a lot of other things to be out of place as well. So that's why when we look at thyroid, That's why I draw thyroid on the panel when I'm consulting women about perimenopause and menopause. So a lot of times you can be correcting one and the other one starts to fall back into place. Does that make sense? And so a lot of women have had Hashimoto's or Graves disease or whatever it is.

35:54And yes, it's a chronic autoimmune disease. but a lot of times it's missed by maybe if I start correcting the hormones of estrogen and progesterone slowly we can start to see them them equal out and not have as much of an issue so when it now comes to working out I'm I'm trying to answer the question as how I'm hearing it is that going overboard will that impact the Hashimoto's thyroiditis or if that could be done yes i think working out always is going to decrease inflammation and when you think about a chronic autoimmune disease it has a lot to do with inflammation as well so i don't quite know where in the question where it meant like working out too hard versus at your level i think obviously the best place to start is at your level another thing to do it to being like let me do a full review of my hormone panel and seeing if there's anything that we could do from the reproductive phase of the uh hrt that might help with the thyroid function and then also with your food as well i do think that there are very holistic ways in which people can have their food or their nutrition support an autoimmune or anti-inflammatory through diet our gut our gut is a big part as well as what lets things in and out and what things may be contributing to this autoimmune type of disease.

37:23And so I think that there are wonderful functional nutritionists out there that kind of help look at the big picture and then help from a nutritional standpoint, figure out what's going to help that issue the most. That's great. So for someone that is on HRT, they're 55. How many years, if not for my lifetime, would you recommend staying on? yes this is a very controversial question because of where we are currently in hormone literature have been for the last 20 years fixated on a study that really had us running away from hormones and thinking that they're bad and we're now just on the other side of it in the sense of hormones are not that bad they're not bad at all they're actually very beneficial.

38:12So there were a lot of recommendations that were made with that study 20 years ago. And one of them was stop taking HRT at 10 years at the time you're menopausal. So if you stopped having periods of 52, 55, then you just add 10. That's when you stop or no longer than 60 years old, right? Whichever pertains to your issue or your age. The problem with that is that we know from literature, the moment you remove estrogen, progesterone, and testosterone from your body that have been there your entire life, then your organs are also going to take a hit because they're not being substantiated by the hormones.

38:54So we're just at this early state of research to say, how long should women go on? There are a very big body of doctors that are like, from a longevity standpoint, why would I go off hormones? Because it helps bone mineral density, decreasing rate of Alzheimer's, decreasing rate of breaking your bone, improving your muscle mass. And so it's more now as we start to age, how can I thrive while I'm aging? And hormones have a lot to do with that. But also we have strict recommendations based on studies that are like, well, we really shouldn't go past this point. Where do we think that we're going with research is more towards I'm going to be on hormones until you desire to, or until you die.

39:42Um, and I think when you have a really good conversation with someone who truly understands hormones, people get, should be able to make the decisions that they want to based on the information that they get. We're still in that phase where they're going to be like, oh my gosh, you are 62 and you're still on MHT. We've got to get you off. I have patients who are 70 and they're like, I feel great. I'm not coming off my hormones. And I'm like, rock on. So again, you're going to, people really need to get to the point where they're like, of all this stuff with risk and benefit. And what I'm looking for is I'm looking at my life in my 60s, 70s and 80s, nineties, what I want that to look like, how is this helping?

40:25How many of you want? As we age, age is probably the risk factor for most diseases, breast cancer, heart disease, Alzheimer's. So as we age anyway, things start to not function as properly, disease goes up. But if you were to think of it in a way that says, I want to be able to be exposed to hormones to give me the best benefit as I age and quality of life, that's all another way to look at it. But no one's wrong, right? You get to determine which one of those works best for you. And I think that we're going to start to see that it is more personalized as far as a medicine form to say, there's going to be a risk at every point.

41:08Which are you willing to take personally? I love that. Okay. So what do you recommend to your patients with osteopenia, estrogen, HRT, as a prevention for further bone protection or bone loss? And what about creatine? Back up on that question again, start with the first part. What do you recommend to your patients with osteopenia? Would you do HRT therapy as well to prevent further bone loss or for bone protection? Both. you can see considerable amount of improvement in bone mineral density levels and scores if you were to look at it from a DEXA scan perspective when people are on estrogen that has been stated clearly in the literature so if you have osteopenia which is a deficiency not a deficit then I would I would love if someone was like you know what let me give it my best shot of not becoming osteoporotic and go on MHT, do my strength training so I can be more preventative and actually improve my bone mineral density.

42:22Yes. And also with HRT for all of these, that's never going to replace strength training. We have to do those hand in hand. Yes, because they're by different mechanisms in which they're improving the bone. So, for example, with MHT, the estrogen is improving the bone mineral density by improving the osteoclast, which is the cells that make our bones stronger. Resistance training, what you're actually doing is it's kind of like a domino effect. you're triggering your muscles through its fibers as it's kind of doing its twitch to then tell the cells on the bone to improve or to to become more or to build more right so they're both different mechanisms so you're going to get the best benefit from doing both but you know i have patients who have never weight trained or they're scared to weight train i'm like well let's at least start with some estrogen or vice versa.

43:30Right. So it's never to say that everyone's always going to have the perfect template of what they're doing, but at least being able to do one, if not both, is the best way to improve your bone. Yes. I love that. Okay. What is the best non-pharmaceutical intervention to protect and build bone for post-menopausal women diagnosed with osteopenia? Weight training. It's not a medicine. I mean, it's not a prescription. There you go. Exercise is medicine, but that one's not a drug. Yeah. Perfect. That's probably the best way to do it. So if someone was a little bit weird about x-rays, how safe are DEXA scans in regard to radiation exposure and how often is it appropriate to get them done?

44:20so and this is a good question too that i had yesterday so when we look at radiation radiation when we look at it from a rads perspective that's how we we monitor the amount uh that you're getting exposed to dexascan is really low on that list um and and even x-rays and when we think about like exposure to radiation and like the likelihood of cancer it really is for people who are getting like significant amounts of radiation, like every day for like two years. You know what I mean? A lot of the data that came out on, on radiation and cancer, one, it was done on mice, which obviously were not big mice, but it was a good indication of what can happen.

45:03But when you actually look at the studies, it was a significant amount of radiation. So in everyday person's life, who's like, I'm just doing this imaging occasionally with which a DEXA scan. I'll actually, let me go back to, let me finish my statements. I'll go back to recommendations for DEXA and how often to do it, but it really requires a lot of exposure to radiation for someone to say, oh my gosh, I got a cancer from actual, right? Okay. So I want to reassure everyone with that. The other thing about DEXA scans, currently the recommendations for dexascan by insurance is not until the age of 65 which i completely hate because what do you think's happened by the age of 65 our bones are like we were already on our way out like and and so it's not a very preventative way in the way the recommendations are written about dexascan the way that we use it so amount of radiation is very low currently the recommendations at the age of 65 to me i'm just like of course women are going to be they've been usually menopausal for at that point like 15 years without any estrogen and most of them are not taught to weight train so of course their bones are not doing great so what when you think of physicians there again a circle of physicians not to say that's little but outside of the traditional setting who use DEXA scan, not only to look at your bones earlier.

46:35So they might recommend someone to go get it like in their latter forties, early fifties, as they're going through that transition into menopause, because now they're losing estrogen, but also DEXA scans are a beautiful way to look at your lean muscle mass and your actual fat capacity as well. And the reason why that is also important is because your muscle mass too is significantly decreasing over that menopausal, that perimenopause menopausal timeframe. So now your estrogen's going down. That's what I'm saying. Estrogen receptors all over impacts your bone mineral density. Your muscle mass is starting to go down as well, but your fat cells as well, how they respond to estrogen is they just, they're not as agile and shrink as well as they used to before, which is why we start to change our body composition as we start to age.

47:24So DEXA scan is actually a beautiful way to look at multiple things and to help people being a little bit more visual to what's going on internally in their body. So they can start to make the, the changes in the connections in their head and being like, Oh my gosh, look at my muscle mass. And so they're actually, if you go find DEXA scan facilities, they're actually not that expensive. They're like 125 to$150. And if someone wanted to get a good baseline on what their body's doing internally from a muscle perspective and bone perspective and kind of like a fat mat or a muscle fat ratio. Dexa scan is a beautiful way to see that.

48:04It also can be preventative because now, you know, your bone mineral density is at a younger age. And if you wanted to, you could do it every year, you could do it every two years, but it's a great way to see so much more than what we used it for and much earlier is better. Yes. Okay. Would you recommend somebody going on HRT that's not having any symptoms, still has a period and perimenopause, but like doesn't have any headaches? No, no, no, nothing. Yes. You would recommend it. The reason why is this is a very controversial question right now. Because typically we used to wait for women to be menopausal before we would give you MHT.

48:50We are moving away from that and still a lot of providers. And again, not to say that they're wrong, but this is how we were trained. We would say, well, we'll only put you on MHT if you have a symptom. But what do we know happens when you're just declining from estrogen anyway, so many things in your body, it's not always a symptom. So I think that there are providers who will do it. I think that women need to think about those decisions when they sit down and think, am I having a symptom versus am I improving quality of life and longevity? Those are two different things. and actually get the benefit of both when you use MHT.

49:29And so approaching it from that way, rather than I'm only going to go on MHT when I have symptoms. And I really want to make a disclaimer that I'm, you know, as much as a HRT advocate than I am, it does not mean that if you're not on it, then you should be shamed because you didn't go on it. I just want everyone to have the ability to know really good fundamental information. So when they make the decision that they would like to or not, as much as I could be like, I think it's the best thing for you. If you choose not to, then you choose not to. Yeah. This is why I love you because I feel like your energy and your candor is just so spot on.

50:08Like it's not harsh either way. Like it's just, here's the information as a physician and you get to make the choice. Say you change your mind in three years, just because of the information you heard and you just gave it more thought and you had more conversations, right? All of this is really now to get people to then go and being like, Hmm, I didn't know that about, let me talk more about to my friends. Let me bring it up to my doctor. And that's how we change the ability for us to make decisions is because we're changing our conversation. Yeah. Yeah. 100%. Oh, okay. I love it. So I'm someone who is in the age range of, of perimenopause 42, but hasn't experienced any trouble except for a bit of the, let's talk about the visceral fat, because there's a few questions here with, with that, but no other symptoms and have heard that women should do hormone testing before menopause so that they have baseline levels of hormones to aim with HRT.

51:07If they choose that route in the future, should I check, should I consider checking my hormones at this point anyway, if I, or wait until I have further symptoms. If hormone testing is recommended, do you have a recommendation for the test? You went over the test, so we'll remember those. Yeah, so what your hormones are doing today at what time, well, at my time at 6.57 will be different than if I tested them today at 2 a.m. or tomorrow morning, right? And so it's not so much a matter of if I draw it now, will it help me later? It's good to have a baseline to see where you were, but it should not dictate what your dosage of MHT is going to be now or in the future.

51:50It's not so much for, I have to do it now. So I know my dosage will be later. I think that it is good for people to get a baseline, just to have a baseline. And if we decide if you have symptoms in two years, or if you're like, let me see what my hormones are in two years, you can kind of see what that difference would be, but it doesn't necessarily mean that it should dictate your dosage. Yeah. I want to make sure that people understand that. Then the other thing is you asked a second part of the question. It was about the, we went over the, what should be drawn on the labs and you said something about visceral fat.

52:23Yeah. Does the visceral fat, so this is the only symptom that they're having, but then someone else had mentioned, you know, the weight gain with visceral fat and how realistic is it for perimenopausal women to achieve fat loss, weight loss is their hope. And does HRT help with that? yes so i'll answer the first question first about visceral fat so you have your subcutaneous fat which is the fat that we see right so it's the fat that migrates it used to be on your hips and your butt and now it moves to your your abdomen even though you didn't ask it to go there um and then you have visceral fat visceral fat we can't see i have seen visceral fat because i went into someone's organs and looked at it with a laparoscope or i cut them open and was doing a surgery, it's the fat that you see around an organ.

53:13And the fat that's around an organ is for protective reasons. But what happens as we start to get older is that our visceral fat starts to increase. Okay. So that in there and becomes a problem. And that's also what you can see on a DEXA scan as well. Your visceral fat, which we aren't, we can't see just looking at someone externally. So the reason why visceral fat is important because you won't feel when it's increasing, you won't see when it's increasing, but it does impact your organ systems. Okay. And so that's why people start to maybe have like liver issues or heart issues or whatever. That's the reason why weight loss in general will always be one of those biological features that for some people may be more than others, but in general, everyone will start to have fat weight rather increase as they age because of insulin resistance.

54:08The main bulk of why we start to see that happen is because estrogen decreases and we start to have a shift in our muscle mass, so if you have, think of a pie chart and for your 20s and 30s and when you're an adolescent really active and your muscles are very, very, they're thriving, they may take up 65 % of the pie and then you have organs and water weight and fat which take up the other portion. As we start to get older, that 65 % of that pie starts to decrease slowly over time. So what does that allow more space for? More fat, right? And so now we have decrease in estrogen, which is also not helping our muscles.

54:50We have a decrease in testosterone, which is also not helping us build more muscle. So hormone replacement therapy in essence is not directly making you lose weight. It's helping all of the things that were there, part of that symphony to kind of keep everything in check, increase your muscle mass through testosterone. But then the work comes with bulking up your muscle because you're already losing it. So you need to bulk it up to get that pie chart back to what it used to be. And that's why when I see your program, It's so phenomenal because weight training is really saving lives because muscle is the organ of longevity.

55:28It's the thing that keeps us stable. It's the thing that keeps us strong. It's the thing that protects a lot of our bones and also our heart. And that is why it's important to switch to more of a weight training workout than ever when you're going through that phase. We're really trying to get that 65 percent back. Right. And I'm just using contrary numbers, but I'm just trying to give you a, like a kind of visual of what's happening with your body. The insulin resistance part is also crucial because it's not anything that you can see. It's really just this thing that's happening internally. And when you start to have increase in insulin resistance, that means it's not, it's like a mailman.

56:09I always say this, the insulin is like the mailman. It distributes the sugar where it needs to go. And it's like, you are fuel. you're going to the brain so the brain can use you the liver needs you the muscle needs you all of these things but as insulin resistant as we start to age the mailman's like yeah i'm not doing the mail today and then the mail is just sitting around and the sugar is like we have nowhere to go and so it just sits in our blood and then we become more diabetic in a more diabetic phase but the the reason why i love your program again is because the biggest utilizer of glucose is muscle.

56:45So if we're not building muscle and it's already on its way down biologically, the sugar is just going to be like, well, we'll just sit here too, because we're having fun. And then it converts to fat. Yes. Oh, and, and, and to, to answer the rest of this question, yes, you can absolutely lose fat in menopause and perimenopause. Yeah. And I know you live time. I will, I will go on, on, on brand and say, is it easy? No. Can it be done? Yes. Yes, absolutely. Okay, we're going to rapid fire these questions because you got to get off. You got a trip to pack for. I mean, it's only Ibiza. I can't wait to watch all of your stories.

57:28Okay, as menopausal women not on HRT, our libido decreases and orgasms may take longer to achieve. Considering a happy, healthy sexual relationship exists, what natural supplements or adaptogens can you recommend for this? that isn't HRT. Yes. Vitamin B12. There's a medication called Addy E A D D Y E. That's helpful. Vilesi is also a helpful medication that helps with it. Um, I definitely am. There's a, gosh, it's a niacin. It's a little, it's over the counter, but it's a little gel that you can put on your clitoris, increasing and enhancing PRP injections. Oh, shots. They do help. I really do like those.

58:15There's so many other ways than taking testosterone, but when it comes to libido, all I would say is women do not let that go. We are entitled to pleasure. We are entitled to having really fulfilling lives as we grow older. Do not let that go. yes agree mic drop okay would you suggest um okay so we talked about if somebody was just having hot flashes would you suggest to stay on hrt um after 60 i guess that goes back to quality of life of what you want quality of life but i'm gonna give a very big nod to yes because i have patients who are in 70 and having hot flashes like i can't tell your hot flashes to stop right I would love to print there, but if they're still there, you need estrogen.

59:02Yeah. And progesterone. Yes. Yes. I learned that from tonight. So that was new to me. Okay. What do we know about safety of oral micronized progesterone compared to progestin? Is it associated to breast cancer or cardiovascular diseases or any other risks? Very easy answer. Progestins. please just don't take those. Those are what in that study 20 years ago, increased risk of breast cancer. So those are synthetic. Really look at your micronized progesterone and stick with that. Yeah. Okay. Awesome. What are your thoughts on estrogen products for the face? Do they work to improve the skin and are they safe?

59:49Yeah. So they are safe. It's estriol, which is a weaker form of estrogen. So it's not like it's getting absorbed in your face and it's in small amounts. It's not in beginning absorbed and it's going to course through all throughout your body. It does work because you have estrogen receptors on your skin as well. And so they respond to it. They make it more plump, increase vascularity to the area. Is it the fix all for everything? No. What I would say is using that consider your, your Botox, your lasers, your microneedling really like really pay attention to your skin because that's like the thing that we see and it is impacted by menopause so start to invest more in that area so you just you feel great about yourself but estradiol or estriol or estrogen creams in her face are are good and they are safe yes i'm getting some that's been on my list but i just don't have two seconds to actually even go to the dentist.

1:00:45Right. That's me. That is me. Okay. Um, any thoughts on taking adaptogens like ashwagandha while also on estrogel, um, prometrium and testosterone feel as though the HRT doesn't help so much for mood related symptoms. Say that one more time. You put a lot in there. yeah this i'm just reading this how how they wrote it and any thoughts on taking adaptogens particularly ashwagandha um while also on estrogel prometrium and testosterone but she feels like hrt doesn't help so much for the mood related symptoms great okay so now i get the question so yes ashwagandha is an aptogen i think aptogens are wonderful as natural substances and they really help balance some of the other things that are going on in life as much again as much as a hormone advocate that I'm, that I am, there are other things that we can be taking that can also, uh, supplement or, or help them rather.

1:01:47So yes, as an aptogen, that's completely fine to take. The one thing that I would say about, if you feel your hormone replacement therapy isn't working for you, then you need to find someone. And if someone's not adjusting it for you in the manner in which you need it, cause it's personalized, it should never just be everyone's on the same dose. so someone may need to adjust that for you but aptogens are a great way to kind of balance and use natural ways to create more of the substances in your body and the hormones to respond better so yes you can take that at the same time there's one the one on here that i want to answer how do you know if you're insulin resistant when you get those labs that i uh talked about earlier hemoglobin a1c is a good way to tell where your body is is how it's processing sugar i guess you could say, or glucose, get a fasting insulin and a fasting glucose, because then you can do an insulin glucose ratio and see how your body is actually absorbing, utilizing glucose.

1:02:43That can give you a good idea. If you're going more towards insulin resistance than not, but just in general, everyone, their body biologically just starts to get more. Yeah. Okay. Fabulous. Is there a minimum known estrogen dose, estrogel or estrodot for osteoporosis prevention? That's a good question. There's no minimal dose. The goal really is to get you started on it. And the reason why I say that is how we measure bone mineral density is through like a T score and a Z score, which is arbitrary. You don't need to know about that, but everyone kind of has a score of where they are. So a lot factors into where you are, your age, your ethnicity, if you're a smoker, and also like your DNA, like, you know, your family history of what your bone structure is made up of.

1:03:37So there's no minimal dose. We're really just trying to improve who that person is and where they are based on all those things that I mentioned. So estrogen is going to help, but there's no minimum dose. Okay, we are almost done. How does being overweight affect symptoms of perimenopause. I'm on HRT for improved sleep, joint relief, and minimizing hot flashes and night sweats. It works, but I've gained five to seven pounds since starting HRT a few months ago. Is there a correlation between weight gain and worsening perimenopausal symptoms? Yes. So there are some people who, when they start HRT, can start to have this like slight little bump with that five and seven, five to 10 pounds.

1:04:16Most times it is transient, transient meaning that it will even out the other part of that is progesterone again the comfy hormone does sometimes like to absorb water right and so you may you may be more water retaining because of the progesterone so things or to offset that would be again with weight training it's going to build your your muscle increase your protein intake because that is and your fiber intake. If there are probably three things that I would mention in dietary to focus on, obviously there's a lot more vitamin D making sure sometimes you mix it with ADK so that it's absorbed in the intestine, vitamin D protein intake and fiber, right?

1:05:01Remember we talked a little bit about gut health. So again, making sure that we're keeping our gut in the most healthy way so that we're not again, losing things that we want to keep in and things are coming in that we don't want to come in. Yes. Okay. Great information. Is there a chance of inflammation and joints increasing significantly as women approach post-menopause in particular, the hand and finger joints? Yes. Inflammation. There's a great company. If you wanted to look it up, it's called Glycanage, G-L-Y-C-A-N-A-G-E. And they're not the only one who does this, but what they actually look at is from your biomarker.

1:05:40So they take your blood and look at your inflammation factors because there is such great data as we start to decrease in estrogen, inflammation increases. So two things cause inflammation. One, well, actually a lot does our diet, our age, as we start to age, we just become more inflamed. And then also menopause contributes to that as well. So many women start to have joint issues. I have a lot of women who that's their presenting symptom of menopause. We get them on HRT and their joints are not as achy. Musculoskeletal syndrome of menopause is real. Most people might complain of a frozen shoulder, but joints are also part of that as well, as well as lower back pain too.

1:06:23Okay. What would you recommend for vaginal dryness? HRT or another natural way? Ooh, I love this because I do all of them in my office. So vaginal estrogen. So it would be, you're not going to get as much bang for your buck. Let's say if you take systemic HRT, like a pill, a patch, a cream vaginally, but a vaginal estrogen cream. Yes, there also is the laser, a CO2 laser that can really help restore a lot of the vaginal tissue. And then there's also radiofrequency, which can also help get to the deep layers of the tissue in the vagina to help restore the vascularity and also secretions. and then PRP, PRP injections can be, we can do that for hair.

1:07:06We do it in face, but we can also do it vaginally as well to kind of help restore that. So that's like four great different ways that you can do it. If someone wanted to do HRT and a blend of some of the other things or non hormonal and do investigate the other three. I mean, thank goodness for this day and age, right? Right. I know. Okay. Almost done. Um, I'm 51 and, and for the last year I've been on birth control to help me with perimenopause and have very heavy periods. I had an ultrasound prior to rule out other causes of excessive bleeding. I've been fine on birth control and the pills are controlling my periods, but I'm wondering if I should switch to HRT.

1:07:45What are the, oh, okay. So that's another, oh, over the counter. So probably time to talk to her physician about possibly switching. Switching? To HRT. From what though? From nothing? Birth control pills. Oh, yes, yes, yes. So she wants to, but she's unsure of what? Yeah, she has very heavy periods. So I think that's why she's been on on the pill. She's been doing fine on the pill, but then I'm wondering if she should switch to HRT instead. If she has heavy bleeding, I would navigate another form of birth control because she's not going to get the control of bleeding with the HRT. So really, and I say this because I have one myself, but IUD is a great way to control bleeding.

1:08:32And then you could still go on HRT. You could also, there's also medications for heavy bleeding that are just for the heavy bleeding. And then you can kind of do the other stuff, which would be HRT. So I think that, or small procedures. So it's not a surgery, but there are small things that can actually help with heavy bleeding as well. So that one actually has like a longer cascade, I guess, of lists that can be done for that part while considering do I switch over to MHT? So it's two separate categories. The bleeding is a category that needs to be addressed with medications, non-medication or non-hormonal medications or procedures.

1:09:08And then the other side would be, do I stay on birth control or do I switch to MHT? Two separate things. Yeah. Okay. What effect on menopause does an IUD have for women in, for a woman in her mid forties? Say that one again. What effect on menopause does an IUD have on a woman in her mid forties? Great birth control and no bleeding. That's coming from a personal experience. It really was designed to be like this really great local way to decrease bleeding, provide birth control. that's low maintenance because you don't have to take something every day, change something out. But it doesn't have an impact on menopause.

1:09:50It helps with the bleeding portion of someone who's perimenopausal and also provides birth control while you can still address considering MHT in the perimenopausal phase if you wanted to. Okay. Okay. We're wrapping it up. What are your thoughts about when this person entered menopause, she started experiencing recurring UTIs and urgency and continence. Do you recommend a hormone therapy for women in similar situations? Yes, because the bladder that member, you're talking about the sphincter and it doesn't control, it's not as tight as it needs to be. So in the moments when we're trying to hold our urine, it's still a little open.

1:10:30So urine can come out. HRT can definitely help restore some of the tissue in the sphincter and in the urethra. The other good thing in why, even if it doesn't correct it, even if you needed a procedure or a laser or something else, you're now being preventative by using HRT, namely vaginal estrogen in this instance, because as you start to get older, it's only going to become more of a problem. And a quick statistic, when you look at actual old age homes, most of the women, a lot of times they're usually are having issues with chronic UTIs because of either losing urine or their their bladder is not working to the best capacity that it can because of the microbiome in the bladder, because it's no estrogen is being provided.

1:11:26and that can lead to so many other mortalities and diseases and issues in older age for women. So protect your urethra, consider vaginal estrogen as both helping with symptoms and also being preventative for later on in life. Okay, fabulous. Two more quick questions. If a woman went through menopause five years ago, is it possible to start HRT to treat lack of libido? oh, is it too late or is it too late to start? I always say it is never too late to try anything because at the end of the day, if it works for one, but doesn't work for another, like we still tried. Testosterone is a beautiful way to restore a hormone that was already there.

1:12:10Women have testosterone. We are just put in this category where everyone thinks that we don't have it and only men have it. But we should be just as happy to be the sexual beast that we are and that should not decrease with age. And so I think it is always worthy of someone to consider starting testosterone therapy and considering to increase dosage until they might feel that they do have their libido restored and not to give up on that. Oh, I love that. I hope this is considered general enough. I wondered if you could touch on how fibroids affect active women, what lifestyle changes should we be making if we develop them?

1:12:50Yeah. Fibroids are actually up to 70 % in black women and 50 % in women of all ethnicities have fibroids, right? So a lot of it has to do with when we think of fibroids, we think of size, amount, and where they're located. So most women, if you listen to those statistics, either half or most women will have fibroids, but most of us don't even know, right? but 25 to 30 percent of women are symptomatic meaning they're big and they take up size or they have heavy bleeding so there are really a lot of modalities that are out there to help with the symptom if you do have a symptom if you don't have any symptoms and maybe on an ultrasound saw that you had fibroids typically we can being like okay if they're not bothering you can kind of just monitor them are causing an issue so many different modalities that can help with the symptom that it's causing because there are multiple symptoms that can cause but throughout the perimenopausal phase i would say that fibroids sometimes can start to wreak havoc because our hormones are doing that roller coaster remember how we started the roller coaster ride and that can actually create heavy periods for people who are like i i never used to have heavy periods and all of a sudden they start to have heavy periods could be a cause of the fibroids that are being responsive to this hormone fluctuations.

1:14:14But a lot of women have fibroids. They just don't have symptoms. Jessica, I adore you and I'm so grateful and I'm so sorry we kept you a few minutes over. Thank you so much. I mean, so many of these questions, not only, I mean, I didn't have time to really read the thank you for all you do, Dr. Shepard, Dr. Shepard. So I was just like Trying to get to them, but so much love from this group of women and so much love for what you're doing and just who you are as a person and a physician. So thank you. Thank you. Thank you. I can't wait to track you while you're experiencing Ibiza.

1:14:55Have fun while you're there, along with work. I can't wait for us to get together. I hope everyone who is on here, thank you for investing in your health and being here. But when you see Haley and I together next time, she will be busting my butt. And then you guys can be like, wow, she's really kicking her ass. I'll be like, yeah, that's what she does. Exactly. We're making it happen. Yes, we are. Okay. I adore you. Take care. And thank you so much. All right. Have a good night. Bye. Thanks for listening. If you enjoyed this episode, please consider giving us a five-star review and sharing the body pod with your friends.

1:15:35Until next time.

From the publisher
RE-RUN – Back by Popular Demand!

Join Hailey as she hosts a fan-favorite Q&A session with the one and only Dr. Jessica Shepherd, a leading expert in women’s health and menopause. In this encore episode, Dr. Shepherd answers the most common questions about menopause symptoms, treatments, and how to manage the physical and emotional changes during this stage of life.

From hot flashes and mood swings to hormonal therapy and wellness tips, Dr. Shepherd shares her expert advice on navigating menopause with confidence and maintaining overall well-being. Whether you're currently going through menopause or preparing for it, this episode is packed with valuable insights and practical tips to help you feel your best.

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RE-RUN - Menopause Q & A with Dr. Jessica Shepherd: Expert Advice on Symptoms, Treatments & WellnessThe Body Pod · 1 h 15 min
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