Health Experts Reveal What’s REALLY Making You Sick | Roundtable

8 Sep 2026 · 2 h 2 min · 47 chapters

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In short

The episode is a “cellular medicine” roundtable arguing that many chronic diseases start with cellular dysfunction (especially insulin and cortisol dysregulation), not just organ-level symptoms. Guests claim that fixing root cellular drivers can “reverse the irreversible,” and they emphasize sleep/circadian rhythm, inflammation, and nervous-system regulation (vagal tone) as key levers. They also discuss trauma and faith-based approaches as upstream causes of persistent plateaus.

Guests (backgrounds)

  • Dr. Josh Axe: Functional medicine clinician with long practice experience; focuses on cardiometabolic risk, blood markers, and cellular aging. Co-authored Heal Your Cells with Dr. Will Cole.
  • Dr. Will Cole: Cellular medicine/functional health physician; co-authored Heal Your Cells; emphasizes energy, autoimmune reversal, mitochondria/cellular health, and stress/trauma drivers.

Key claims

  • Cellular dysfunction drives organ dysfunction; mainstream medicine treats downstream organ effects.
  • Insulin resistance is central to cardiovascular risk; cortisol dysregulation drives stress physiology and early-morning awakenings.
  • Poor sleep (<6 hours) can rapidly worsen insulin resistance/inflammation.
  • “3 a.m. wake-ups” are framed as a cortisol/parasympathetic (vagal tone) issue.
  • Childhood trauma can stall progress even when protocols work initially.

Notable examples

  • Stanford/Nature 2023 study: ~20% (guest says clinically it may be closer to ~50%) have one organ aging faster; neurological and immune aging are described as most deadly.
  • Blood-panel examples: glucose/A1c targets (e.g., fasting glucose <90, A1c ~<5.5), triglycerides <100, hs-CRP <1, homocysteine <7, plus ApoB and Lp(a).
  • Personal story: one guest reports high Lp(a) and plaque despite “walking health,” and a father’s heart attack at 59.
  • Practical vagal-toning example: gargling for ~2 minutes to shift into parasympathetic state.

Written by AI. May contain mistakes. Listen to the episode to check what was said.

Chapters

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Exploring Cellular Medicine

3:44 to 5:01

Discussion on the future of medicine and the importance of cellular health.

“All right, everybody, welcome to The Roundtable.”

Understanding Cellular Dysfunction

5:01 to 8:07

Insights into how cellular dysfunction leads to chronic health issues.

“And there are all natural solutions to these that we can fix a lot of these issues with.”

The Aging of Organs

8:07 to 12:26

Examination of how organs age and its implications for health.

“So instead of us being archaic dinosaurs of still looking at just the organs and realizing there's so much more at play here, there's actually a cellular dysfunction.”

Blood Panel Insights for Heart Health

12:26 to 14:00

Key indicators on blood panels that reveal heart aging and solutions.

“Now, according to that study that Will's talking about, and this is one we dive into in the book, certain systems aging faster than others is much more deadly.”

Understanding Cardiometabolic Issues

14:00 to 19:04

Learn about key factors in cardiometabolic health and the importance of blood markers.

“And if we see that, what do we have to do to address it, given the problem?”

Explaining Insulin Resistance

19:04 to 19:28

Gain insights into what insulin resistance means and its implications for health.

“You've got to do some different things, make some changes.”

The Impact of Insulin on Hormonal Balance

19:28 to 23:00

Explore how insulin resistance affects overall hormonal health and functions.

“Yeah, so I mean, insulin resistance is where we have these beta cells.”

The Impact of Insulin on Hormonal Balance

23:02 to 23:39

Explore how insulin resistance affects overall hormonal health and functions.

“another protocol that works for three weeks, and then it stops working, you're not missing discipline.”

Sleep's Crucial Role in Health

23:50 to 28:04

Understand the critical relationship between sleep and insulin resistance.

“And I want to do this fair because I know how this goes.”

The Importance of Sleep for Health

28:04 to 29:14

Learn why sleep is critical to overall health and how poor sleep disrupts bodily functions.

“I want to say it was the craziest sleep schedule.”
Show all 47 chapters

How Sleep Affects Hunger and Mood

29:14 to 30:22

Discover how lack of sleep leads to increased cravings and irritability.

“I mean, you can absolutely destroy your health with poor nutrition, high stress.”

The Science of Sleep Cycles

30:22 to 32:38

Explore the different phases of sleep and their importance for health.

Addressing 3 a.m. Wake-Ups

32:38 to 35:39

Learn how to manage early morning wake-ups and their relation to cortisol.

“It's a counterfeit to be sleeping during the day.”

Strategies for Improving Vagal Tone

35:39 to 37:53

Find out techniques to enhance vagal tone for better sleep and health.

“So actually our CEO over here, Adam was telling me, I told him, I'm like, get this device.”

Mental State and Physical Health Connection

37:53 to 41:39

Understand the link between mental well-being and overall health outcomes.

“because what's happening there mechanistically is that cortisol is supposed to be increased in the morning.”

Morning Routines for a Better Day

41:39 to 42:00

Learn how a structured morning routine can enhance mental clarity and focus.

“And that just shows you this, like someone's heart state and their mental state, how that impacts so many different things, right?”

The Importance of Morning Routines

42:00 to 43:44

Learn how establishing a mindful morning routine can enhance your mental state.

“and I started to do this in the morning where if I don't get up, do all my prayers.”

Addressing Childhood Trauma

43:44 to 46:01

Explore how unresolved childhood trauma can impact health and personal growth.

“So my audience will have heard me say this before, but my favorite quote in the world is an AW Tozer quote.”

Connecting with God Through Quiet Moments

46:01 to 48:06

Discover the value of quiet time and solitude for spiritual connection and health.

“And I'm like, you know, I don't know if it's possible for me to get like just a quiet moment.”

Mind, Body, Spirit Connection

48:06 to 50:08

Understand the holistic approach to health that integrates mind, body, and spirituality.

“Maybe it's just time because you've improved.”

The Role of Gratitude in Health

50:08 to 54:06

Examine how gratitude can enhance health and overall well-being.

“That's why I always, when I go do something, I don't speak off of scripts.”

Biblical Principles for Modern Life

54:06 to 56:00

Learn how biblical teachings can provide guidance for contemporary health and wellness.

“And so all that being said, there's a level of like, this is true in sports.”

The Importance of Faith and Emotional Well-Being

56:00 to 1:00:00

Discussing how faith and emotional practices can enhance life quality and cellular health.

“You know, when you watch your favorite movie, 20 some odd times, you always find something new in there that you didn't see.”

Peptides: Future Prospects and Realities

1:00:00 to 1:06:40

Exploring the potential and current issues surrounding peptide therapies in medicine.

“I would like to get into some peptide-related discussion, but I want to go a little bit deeper.”

Integrative Approaches to Cancer Treatment

1:06:40 to 1:10:02

Examining the balance between conventional and alternative treatments in cancer care.

“Yeah, I think the thing that I have a hard time with is that, I'll give you this with the cancer industry as an example.”

The Flaws in Heart Healthy Menus

1:10:02 to 1:11:28

A discussion on the inadequacies of hospital heart-healthy menus and their implications.

“And 50 still don't, which boggles my mind.”

Importance of Gut Health for Longevity

1:11:28 to 1:13:04

Exploration of gut health as a significant factor in aging and overall health.

“I look at markers like, you know, more obscure things, too.”

Exercise and Aging: Building Muscle Safely

1:13:04 to 1:16:01

The role of exercise, particularly strength training, in maintaining health as we age.

“is a lot of different things that can impact microbiome health.”

Injury Prevention and Smart Training

1:16:01 to 1:17:43

Discussing the importance of smart training methods to prevent injuries as we age.

“And I just went with them two weeks ago.”

Dietary Flexibility and Individual Needs

1:17:43 to 1:20:51

The significance of metabolic flexibility and individualized dietary choices.

“And I tried to be patient because I've already explained this to her.”

Navigating Extreme Diets: The Case for Balance

1:20:51 to 1:24:00

Analyzing the pros and cons of extreme diets like keto and their impact on health.

“Now, I want to do a little bit of diet questions with you guys, especially because this has been it's getting so polarizing now.”

Understanding Macronutrients and Individual Diets

1:24:00 to 1:25:19

Learn how individual emotions and stress can influence dietary needs and macronutrient balance.

“Part of the reason is that like, this is from Chinese medicine.”

The Complexity of Diets: Tools vs. Lifestyles

1:25:20 to 1:26:07

Explore the nuances in diet approaches, emphasizing personal lifestyle and health goals.

Bio-Individuality in Dietary Recommendations

1:26:08 to 1:27:42

Discover the importance of tailored diets based on individual health conditions and needs.

“And that's what you said, knowing your body.”

The Role of Context in Nutrition

1:27:43 to 1:28:48

Understand how context and personal experiences influence dietary choices and perceptions.

“And what we're able to do with our work at the Health Institute is create that bio-individuality of knowing the nuance and context of, and books are great.”

The Debate Over Seed Oils in Diet

1:28:49 to 1:30:11

Analyze the conflicting opinions surrounding seed oils and their impact on health.

“You know, and a part of it is messaging.”

Exploring Fats and Cardiovascular Health

1:30:12 to 1:34:51

Delve into the complex relationship between dietary fats, heart health, and individual differences.

“This is more of a passion project for me because of how I feel.”

Real-World Data vs. Clinical Studies

1:34:52 to 1:38:00

Examine the need for real-world data to complement clinical studies in understanding health.

“and do things like butter and tallow as long as the caloric intake stays low or below a certain level.”

Skepticism Towards Studies and AI Responses

1:38:00 to 1:40:10

The discussion revolves around the reliability of studies and the role of AI in health information.

“You can't monitor what everybody's doing.”

Survival Foods: What's on Your Plate?

1:40:10 to 1:41:30

Participants share their ideal survival foods and discuss nutrient density versus enjoyment.

“or whatever, one of those questions, but you could only have five foods that you had to live on.”

Favorite Cheat Foods Revealed

1:41:30 to 1:44:20

The hosts reveal their favorite cheat foods, discussing indulgences and cravings.

“Yeah, I would do a grass-fed burger for sure.”

The Protein Debate: What's the Right Amount?

1:44:20 to 1:46:50

Discussion on the current trends regarding protein intake and its effects on health.

Fiber's Role in a Healthy Diet

1:46:50 to 1:52:00

Debate over the necessity of fiber in diets, especially in relation to carnivore diets.

“Now, right now, it's the protein extreme.”

The Implications of the Carnivore Diet

1:52:00 to 1:53:12

Explore the potential issues related to the carnivore diet, including pH balance and bowel movements.

“autoimmune or mold or some sort of thing where your immune system is on high alert constantly.”

Gut Health and Fiber Considerations

1:53:12 to 1:54:24

Discuss the importance of fiber for gut health and the need for personalizing dietary recommendations.

“And maybe your question was also there about fiber.”

Bio-Individuality in Nutrition

1:54:24 to 1:56:28

Understand the concept of bio-individuality and the importance of tailored dietary approaches.

“may not have some fiber, but the polyphenols themselves build and promote bacterial diversity.”

Messages of Empowerment and Healing

1:56:28 to 1:58:26

Hear final insights on personal health, resilience, and the importance of tailored protocols for healing.

“Yeah, well, I'll just say that I think it's important to know that God designed you uniquely.”
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Transcript

Automatic transcript. May contain errors.

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1:18Really what it is, is actual cellular dysfunction that's going on here. It's insulin and it's cortisol. And if you can fix those two hormones, every other hormone would go back to where it should be. I found that I had a high LP little a, I found plaque, and I was supposed to be the epitome of walking health. My dad had a heart attack when he was 59. I didn't see that coming. The amount that your insulin spikes from less than six hours of sleep is just wild. Sleep is not a luxury. It's a mandate on our health. It's non-negotiable if you want to live long and thrive. I used to kind of live by this all gas, no brakes, never rest.

1:52You think that you're training and doing all of these things that are so great and macho and everything else, and you're just the epitome of poor health. Just because you hear about it on a podcast or read it in a book doesn't mean that you have to do all the things. It's always confusion. People going, well, what can I even do? What can I even eat? We're creating a bigger problem. We're literally creating stress when we do that. We have such a hubris and arrogance today because we need a randomized control trial. But now the great thing is that the randomized control trials are substantiating what God always said.

2:19Surprise, right? God knew what he was talking about. If I have a patient and they start seeing some results, but then they just hit this plateau, there's a childhood trauma that's just never been dealt with. and that's just continually on replay. I'm not smart. I'm not pretty. I'm not pursued. I'm not loved. People that are still against people in functional medicine, they're on the wrong side of history because the data speaks for itself. So people are still like it's us versus them. This is not radical. Getting people healthy should not be offensive. If it is, look at your heart.

2:57Now, I don't say this lightly, but I believe that the information in Heal Your Cells is the most important health content that you'll read all year. And my new book that I wrote with Dr. Will Cole is now officially available at Amazon, Barnes & Noble, or wherever you get your books. And here's the part I don't want you to miss. When you go to Healyourcells.com and add your email and your order number, we'll send you hundreds of dollars in bonus resources, including the cellular peptide guide, the cellular supplement guide, and a masterclass in 40 longevity recipes. Order your copy, then head on over to Healyourcells.com.

3:36That's Healyourcells.com to get hundreds of dollars of content for free today. All right, everybody, welcome to The Roundtable. This is a discussion that we are going to have on everything about today's health and wellness scenario. I am pleasured here to be with Dr. Josh Axe and Dr. Will Cole. We are going to bring you the very best insights that we have. There's going to be some different opinions and thoughts. We're going to compare, We're going to contrast and we are going to do our very, very best to bring you the best guide that we can to health and wellness. So without further ado, my friends, Dr.

4:19Josh Axe and Dr. Will Cole. Thanks for having us. Thanks for having us. Yeah. So, hey, so excited to be here today and excited to jump into cellular medicine. I really believe that's the future of medicine. I know we've got Dr. Will Cole here, a good friend of mine as well. And him and I co-authored a book recently diving into how do you fix your energy? How do you reverse autoimmune disease? How do you reverse the irreversible? When today, a lot of doctors would say it can't be done. Well, today we're going to walk you through how to heal your cells. We're going to really dive into, again, what is cellular medicine?

4:48What is the mitochondria? How do we fix that? And one of the things I know that I've seen in practice is conditions like hypothyroidism, perimenopause and menopause, infertility, low testosterone. And a lot of times these are cellular issues. And there are all natural solutions to these that we can fix a lot of these issues with. diet, herbs, advanced therapies, and so much more. Yeah. So we're going to dive into certain questions today when it comes to cellular health and recovery, but we're going to cover the basis on different aspects that I find Will and Josh to excel at that I want to get the intuition on.

5:24So first things first, you guys just co-authored one of the most amazing books that I've ever read. I had the blessing of getting an early read on it. And so the book is called Heal Your Cells, correct? Yeah. And so I would like to dive into cellular health today first, because what I have found, and admittedly, science was my least favorite subject my entire life till about two years ago, and I have enthralled myself in cellular health. Now, I want to know from both of you, when you're looking at total health and you're analyzing people and you're looking for things that may be going wrong. Correct me if I'm wrong, but is the cellular side of the very most important part of health that we need to tackle first and look at when it comes to someone's health?

6:11Yeah, I think, look, this topic is without a doubt the root cause of why we're facing such an epidemic rise of chronic health problems. And when you look at it, I see a lot of people, telehealth patients that have autoimmunity specifically, okay? And it's easy to see with autoimmunity when the immune system is attacking certain parts of the body. Mainstream medicine, conventional medicine is looking at organs oftentimes, right? The immune system's attacking the thyroid, it's Hashimoto's disease, or it's attacking the gut, it's all sort of colitis and Crohn's or the myelin sheath in the nervous system, the brain, it's MS, right?

6:48And even if it's not autoimmune, inflammation is really the commonality between just about every health problem. But mainstream medicine is largely looking at organs, systems. Really what it is, is actual cellular dysfunction that's going on here. So they're dealing with a downstream macro dysfunction. They're not actually dealing with the root causes, but you look at all the latest science in as far as longevity is concerned, people living long, healthy lives, meaning not having those diseases that they're diagnosed with. It's dealing with cellular dysfunction and the ripple effect of cellular dysfunction is where you get organ dysfunction.

7:25So one of the hallmark studies that we talk about in the book is a Stanford study was published in 2023. And those researchers found as published in Nature, I believe one in five people in the study, it equals to about 22 million Americans have one organ aging more rapidly than other organs. What that means on a practical level is if that the researchers found if the heart cells, meaning that organ, but the cells of that organ were aging more rapidly, you are at over a 200 % increased risk of a heart attack, stroke, heart failure. Your brain, if your brain cells are aging more rapidly, you are about at 80 % increased risk of neurodegenerative.

8:03So yeah, it absolutely is the most cutting edge aspect of it. So instead of us being archaic dinosaurs of still looking at just the organs and realizing there's so much more at play here, there's actually a cellular dysfunction. And when you address that root cellular dysfunction, you can have healing. And the subtitle of the book is reversing the irreversible, which is a bold statement that we can tell you the D behind that, but it's going to ruffle some feathers, but it's true. It's absolutely true. These things are, it's a paradigm shift for people to realize that you can actually heal at the cellular level.

8:35So you guys brought up points that you just said about the aging of organs. And I kind of got a little freaked out last night when I was reading about that, because that's not something that I am accustomed to reading or seeing. and then i started to look into what had happened with both of your fathers my father passed away when he was 59 so i can relate i wasn't in tune to the cellular side of things and understanding what you guys brought up i want to convey to people the importance of looking at cellular health early what age would you start to say okay we need to start looking at certain aspects of our blood panels and habits.

9:17And Josh, I'd love you to get into this. What are we looking for at certain stages of life? So let's say like 20 years old when, you know, they're telling you, oh, you don't need to worry about this. You don't need to look at this. That frustrates me to the highest level, you know? And so what are some things, stage of life that we need to be aware of and what can we address early that's going to prevent some of these things? Yeah. Well, I mean, I think it really starts at infancy. I mean, I know that's going right back to the beginning, to you, but let me say this. I mean, here's an example. I know when I started my practice, this was nearly 20 years ago now.

9:48I would have mothers bring in their daughters that were starting to have a number of health issues. But one thing that a lot of people, quite a few people are aware of now is women are hitting, a lot of young girls are hitting their menstrual cycle at 10, 11, 12 years old, commonly 13, when really it shouldn't be until at least 16 and 17. I mean, So a lot of girls, if you're hitting it at 12 rather than 17, your hormonal system is aging five years early. I mean, think about that. And then what does that lead to in the future? Well, increased risk of breast cancer, most likely. And then later on, of course, hitting perimenopause and menopause much earlier.

10:28But overall, I mean, a lot of this dysfunction starts off when we're children with insulin resistance is major. We know type 2 diabetes in children, insulin resistance is much, much higher. So all that being said, I think they're really looking at, and by the way, I do want to say something else too. That study said, and it was looking at some very basic markers and saying, okay, they looked at a number of organ systems. They found about 20 % of people had one organ aging faster than others. I will say this though from clinical experience, I think that number is radically higher. I think it's probably closer to 50%.

11:03I mean, I think it's at least double what they have down there. Because right now, I look at blood markers every single day. We run very extensive tests in looking at numerous blood panels. And the number of people that come in with high ApoB, the number of people that come in with, again, other heart markers related to that that are off high blood pressure, that's pretty high. The number of people that come in with prediabetes, that's extremely high. So think about that. I think overall, you've got, I'm trying to think about how many people are diabetic and pre-diabetic. It's close to 50 % of people, right?

11:41And then there's the larger continuum, I think, depending on the study that you cite, right? But I've seen upwards of 93 % of the United States is somewhat on the spectrum. It's metabolically unhealthy. Yeah. So what percentage of people actually are diagnosed, I don't know exact. But the reality is, that's such a reactive model anyways, right? It's like, just wait till you're bad enough to be labeled. By the time somebody's diagnosed, it's four to 10 years prior to that diagnosis that the actual mechanism is at place. Exactly. So again, what I found is most people, when they come in and actually get their blood work done the right way, they tend to be most people, not everybody, okay?

12:16Because I definitely have some outliers, people that are very healthy and don't. But I think around 50 % or more of people have one organ aging faster than the others. And that puts you at great risk of disease. Now, according to that study that Will's talking about, and this is one we dive into in the book, certain systems aging faster than others is much more deadly. The most deadly was neurological. I think the second most deadly was immune system. If your immune system is aging too quickly, I mean, your chance of cancer, for instance, is just radically higher. And then the next one is cardiovascular disease.

12:46So those are the three in terms of mortality rates that really increases your risk of mortality. But overall, I mean, think about the value today of knowing if you have one organ system aging faster than the other. And then one thing we do in the book, Heal Your Cells, is we lay out specifically, here is exactly how to reverse the age of that organ system, because it's different, right? If somebody's neurologically advancing in age too quickly, of course, there's a greater risk of dementia. What do we do there? We want to really send blood to the brain and support detoxification of that channel as well.

13:16So there's ginkgo biloba. There's lion's mane mushroom. There's exercise, extremely important for brain health and in the immune system. There's herbs like astragalus. There's doing medicinal mushrooms. There's drinking more bone broth. There's things that you can do there to reverse the age of that organ system. So there's great value in knowing which organ system is aging too quickly and then having an exact protocol on how to start reversing the age of that organ. Okay. So question then, because this has got me super curious. We're looking at the aging of organs. We're looking at systems. What are some of the most telltale signs on a blood panel that are going to indicate my heart's aging rapidly here.

14:02And if we see that, what do we have to do to address it, given the problem? Give me an example of a problem, maybe a cardiovascular sign, like you said, ApoB, for example. We see that. What do we need to do to address it? And then how do we know if the regression is reversing? What is going to show us that we have a reversal there? Well, you have to compare the data, right? So I think some of the top things, If you want to know about cardiometabolic issues, I mean, the leading driver of heart attack and choke is insulin resistance. So I would actually want to look at someone's metabolic profile and look at the optimal range is not just the lab's reference range.

14:38So people that know this, like the lab's reference range is largely based on a statistical bell curve of people who go to labs. The people that are predominantly going to labs aren't the healthiest population. So in functional medicine, we're looking at optimal, not average. Where does people that live long, healthy, thriving, vibrant lives, that's a tighter interval of where the body's functioning the best, the functional range. So for example, I would look at glucose and A1C. I mean, these are some basic, and this is what's so good about this, is most of this stuff is completely within the, you can go to your standard local doctor and get these labs done and kind of see, it's not the same as the protein markers that the Stanford researchers we're looking at, but it's a good aggregation of more or less how fast or how slowly these cells are ticking.

15:26So glucose, we want under 90, but fasting blood sugar. A1C, we want under 5.5, around 5.5 would be great. Triglycerides or circulating fats, we want to be under 100. If the body has nowhere to put the excess blood sugar, which is fueling the heart attack and stroke, the insulin resistance, the body stores that triglycerides as either fat around the midsection, fat around the liver, fatty liver disease, or circulating fat, triglycerides. So you're going to see broader views for all of these on that lab reference range, whether it's LabCorp request or another lab. So we're looking at these optimal ranges.

16:01And then, of course, we have to look at serum insulin. We want that to be low and healthy. And then inflammation markers, high sensitivity, C-reactive protein under one, homocysteine, another inflammation marker. We want it to be under seven. And then there's liver enzymes, AST, ALT, GGT, because if the liver enzymes are spiked, sometimes that's years prior that you ever become a type 2 diabetic, but you're somewhere on this insulin resistance spectrum. Insulin resistance is the leading cause of heart attack and stroke. That's what's killing one in two people of America is because of insulin resistance.

16:36So that's where I would start. And then from there, you can look at the ApoB, LP little a. And then what I would also run from a cholesterol standpoint, it was called a nuclear magnetic resonance or NMR test, which looks at the particle sizes. So total cholesterol by itself, I mean, you know this, but for people that don't know, total cholesterol by itself, it's like flipping a coin. It's about 50 % of people who have heart attacks and strokes have normal to low cholesterol. So it's like, is that 200 total cholesterol good quality or bad quality? It could be great quality. So it's not demonizing cholesterol by itself, but realizing that's an incomplete perspective.

17:13So we measure what are called small, dense LDL particles, which are actually protein carriers of cholesterol. And we want these oxidized, rusted, inflamed BB bullets, these small, dense LDL particles to be as low as possible. But it doesn't mean we have low cholesterol. It means the quality is better. So these fluffy, buoyant, large, buoyant LDL particles are actually healthy. So you could have 250 cholesterol, but really get great quality. And I'd much rather have that than someone has 150 total cholesterol, but high small dense LDL particles and high inflammation markers. So the context around cholesterol, it's so important because there's so much, because that's where people go to, right?

17:50It's like, oh, if my cholesterol is above 200, that's the devil and I have to get it down. Well, yeah, for most people, other than, I mean, look, other than middle-aged men who who've had heart attacks, and there's a very slight protection that statin drugs bring, the vast majority of people, it's not, the only benefit they're getting from statin drugs is maybe, researchers argue, it acts as a mild anti-inflammatory. Maybe, for some people, that's being benevolent. The reality is it's not cholesterol that's killing people. It's the inflammation that damages the particles that carry cholesterol that's the issue.

18:25And statin drugs mildly maybe affect inflammation. Thank you for pointing some of those things out, because that's kind of on a personal note. And I've talked to you about this, Josh, the struggles that I've had conveying this. I've been studying cardiology five years now with some of the top cardiologists in the world and making this kind of like my life thing because I found that I had a high LP little a. I found plaque and I was supposed to be the epitome of walking health. And this is some of these things are uncontrollable. My dad had a heart attack when he was 59. I didn't see that coming.

18:56And so I want to make people aware of the things that we need to look at so that they can be ahead of the curve. Had I had some blood work done maybe in my 30s or even later 30s, let's say, I would have been on the up and up of knowing, hey, you've got this gene, man. You've got to do some different things, make some changes. Josh, do me a favor. Can you just break down what insulin resistance means? because we say that, but I know some people that have written me when I've talked about it and been like, what is that? Yeah, sure. Yeah, so I mean, insulin resistance is where we have these beta cells.

19:32We have cells on the pancreas. And imagine that you have a, my grandmother used to have one of these. She had a loudspeaker and she would go up and like yell, like in your ear, because she couldn't hear anything, but she would. And literally, and you know, I'd be like, grandma, I'm like, I'm going to go deaf, you know? Was she just doing that to talk to you or just to tease you? Well, I mean, I'll give you the whole background. They owned a campground in Lake. It was like 50 acres. So she did it. But then like sometimes she would do it when you're standing right in front of her. Yeah, just to get you.

20:01Yeah. Got to love, Grandma. Yeah, exactly. But you can basically, these cells can go, they can go deaf, right? So they don't hear anymore. They don't work right anymore. So insulin resistance is where, that's the thing about insulin resistance, right? Your cells become resistant to insulin. They become death. It's not the insulin itself. It's the receptor for insulin because what happens is you have insulin, which is a peptide hormone, and it goes in. Basically, it's like a key, unlocks it to where now it can help bring sugar into the cell. Sugar is fine if it's in the cell because then your cell, your mitochondria, is going to take it and it's going to turn it into energy, ATP, cellular energy.

20:44We want that. but if we have insulin resistance, sugar stays in the blood, okay? And when it stays in the blood, it's inflammatory, it's going to cause the plaque buildup. So to Will's point, it's going to increase the risk of cardiovascular inflammation, plaque buildup, but really inflammation throughout the entire body. And so to Will's point, if there really is a single, I typically say this, there are really two hormones for the most part that I think are the ones we want to pay attention to the most. It's insulin and it's cortisol. And if you can fix those two hormones, typically almost every other hormone in the body will just do exactly what it should do.

21:24It's a domino. If cortisol goes high, now insulin goes high. Well, if insulin's high, every other hormone is going to be thrown out. And when you think about the cascade too, insulin goes high. Well, typically sometimes estrogen will follow it. Progesterone will dropped down. Well, now estrogen's high for men. Well, it's going to aromatize their testosterone. That'll become more estrogen. And there's all these things that happen. But typically, what people will start doing is they'll start chasing the downstream. This happens most with thyroid hormones. It's like, okay, we're going to go and chase TSH all over the place.

21:55If you would just fix insulin and cortisol, every other hormone would go back to where it should be. Yeah. And on that note, as he was talking about this, is that, again, we were talking about insulin resistance, but what is it? It's a cellular dysfunction. So it's talked about in the research as the information theory of aging or the information model. And I like the way that Dr. Axe said it. He said they become deaf. That's what's actually happening is that it can't, the cells lose recognition of self. They get confused. So if it happens in the pancreas or the liver is where the insulin resistance is happening, the liver cells become confused on who they are, how God created that liver is to recognize, I'm a liver cell, but it's forgetting.

22:40It's called ex-differentiation is the term, is that cells all get confused. There's cellular confusion. They don't know how to function and haywire. And then just like humans, when one becomes kind of toxic and dysregulated, the people around them can be kind of dysregulated too. And that's what happens on a cellular level. The whole liver becomes insulin resistant. Listen, if you've started over more times than you can count, maybe it was another diet, another protocol that works for three weeks, and then it stops working, you're not missing discipline. You're missing the foundation. That's what our cellular healing protocols build at the Health Institute.

23:17We've got hundreds of five-star reviews on Trustpilot from folks who finally stopped guessing and actually discovered lasting healing. The first step is a cellular blood work analysis, which is our at-home blood work kit, followed by a full hour review with a senior health advisor who will map out your patterns and show you exactly how we can work together. If you're ready to finally stop the cycle, go to mybloodwork.com. That's mybloodwork.com so we can help you regain your health. Okay, so here's what I want to do. And I want to do this fair because I know how this goes. If I ask you one thing and I want both your opinions, it's like, well he just took all my answers yeah yeah so okay he can have it yeah we both have plenty to say i want one from each of you on both insulin resistance and cortisol what are the main drivers and causes of these problems so give me one for each okay i'm gonna go first though sure okay so for insulin resistance well i can tell you i think from in terms of studies what probably impacts it the most, and it's probably, and I would actually say this for both, my answer is poor sleep.

24:30If somebody's sleeping less than six hours a night, I mean, I want to say, because I covered this recently on a podcast, I mean, the amount that your insulin spikes from less than six hours of sleep is just wild. It's crazy. Yeah, just one night of poor sleep can spike the high sensitivity C-reactor protein that I mentioned. It's true. And that's why shift workers, which can't control that right i mean it's like if you're working a night turn in a factory or a nurse or a truck driver you know people that work the graveyard shift they call it graveyard for a reason i mean they're at increased risk of insulin resistance because their whole sleep-wake cycle is off so part of it's sleep and then part of it's like our connection with light and the way that light impacts the circadian rhythm in fact when we were writing this book together i i spent a lot of time one thing i i really like to do is i like to say okay what does all the current medical research say, but what does all of the ancient practitioners in Chinese medicine and Ayurveda, what does the Bible say?

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25:25I really tried to look at those things. And so I worked with AI on this and I kept asking it, what is typically the first thing in terms of hallmarks of aging or health problems, what is typically the first thing that tips off that cascade? And the thing it came back with constantly was disruption of circadian rhythms was the tipping point for most people. Yeah, it's the light is that it resets the cell clock. So if you're not getting sleep, if you're not sleeping well, if you don't have good sleep hygiene, it's really going to throw it off. And think about even Genesis and the Genesis of disease.

25:55Again, the first thing the Bible is talking about is night and day. I mean, it's very, you know. Yeah, it is a massive one. So that's an interesting pick, but it's true. It is true. People don't think about that. They think, oh, it sleeps this thing. That's like, yeah, we know we should sleep. But it's, are they really prioritizing this deep medicine? Then they're slowly depleting and not to sleep, but like what's their relationship with light and darkness as far as the sleep-wake cycle? It's profoundly important for insulin resistance. I'm going to say something here and I don't want to sound morbid, but you know, that statement, I'll sleep when I die.

26:31And I used to kind of live by this all gas, no brakes, never rest. And kind of that comment, you will die a lot sooner without sleep because you're going to run yourself into the ground. And I have come from that fitness bodybuilding world first before I started to really tackle total health alignment. And you run into this overtraining and that overtraining cascades into this just like dark hole of brain fog and inconsistent eating patterns, inconsistent sleep patterns. And before you know it, you think that you're training and doing all of these things that are so great and macho and everything else.

27:06And you're just you're the epitome of poor health. Can I tell you, though, so I remember I worked as my first job out of high school when I got to college was I worked as a personal trainer for four years and worked in a gym. And I remember, you know, looking at some of the people that were more semi pros or people doing it kind of for, you know, maybe for vanity. And a lot of that culture was, to your point, don't sleep, you know, drink just straight alcohol so we don't like mess up our carb, you know, our macros. I mean, that sort of thing. But here's something else I will tell you. The professionals, the Arnold Schwarzeneggers, the Jay Cutlers, the running cult, those guys, they slept a crazy amount.

27:47I'm talking about 12 hours a day. They would sleep. Yeah, recovery. That's where all the muscle growth happens. You know, in the testosterone levels, that's when they get the highest boost to growth hormone is sleep. It's recovery. If God had to sleep on the seventh day, it wasn't that he needed to. He was showing us the example of this is what you need to do. I want to say it was the craziest sleep schedule. I want to say, and I might be wrong on this, but I thought it might've been Jay Keller, something like this. He slept like four hours and then woke up and then four hours and then another four hours.

28:18He slept three, four hour shifts a day. So they can get enough meals in too for caloric intake. Yeah, recovery is so important. And I lived this world and I trained a lot of professional bodybuilders and athletes. So I saw the ones that made it, that lasted. they prioritized rest and recovery over train train train train train train and not to bring everything back to the cells but i will do that with for heal yourself is that that's where the cells recover yeah that's where these autophagy pathways happen that so the body needs to have the cellular debris to be cleaned up um and that happens when you sleep so yeah sleeping when you're says to say i'll sleep when i'm dead it's it's sleep is not a luxury it's a it's a mandate on health.

28:57It's non-negotiable if you want to live long and thrive. And I will say this too, and I know, Will, you'll agree with us, or I think you will, is that I do think sleep is probably the one that, I mean, you can just absolutely destroy your health so fast if you're sleeping four to six hours a night. But also, I mean, there was a supersize me. I mean, you can absolutely destroy your health with poor nutrition, high stress. You can see people physically aging radically, you know, fast. I mean, lack of movement. I mean, there's, there's a lot of loneliness. That's a whole another category, but that was shown to take something like 14 years off someone's life.

29:34I mean, it's. They're starting with light and sleep, but it's, I mean, if you want more of our hot takes on what causes it, there's a whole list. Oh yeah. There's a whole list. You just brought up what I was actually going to next was when you don't sleep enough, think about how that affects your hunger you you start to have strange cravings in the morning and yeah insatiable food cravings it's throwing off good but it's a whole sleep wake cycles off so yeah you're a hangry monster and you're eating foods that don't love you back because you are at the whim of these dysregulated hormones yeah would you call that like metabolic dysfunction from lack of sleep is that kind of what it would fall under compounds like it's like if you're not sleeping well you're also irritable which which raises impacting your relationships if you're going to be more lonely because people are going to be want to be around you i mean there's a cascade of that where it's it's so important you know what i used to tell myself and then my wife because she's just like why why don't you sleep longer what are you doing this for yourself and i said i just don't feel good when i sleep over six hours i feel like i'm hung over and everything and then i started doing it a few times and then i said okay i'm setting this alarm clock and i'm getting mando seven i'd hope to get eight you know funny how the things we tell ourselves it's like it's so funny because we can identify with these things that may or not be true and make it our personality right it's like i'm a night person i'm a night owl is another one right it's like are you really a night owl or is this just just because something's common you normalized it uh so my daughter just started preschool she went you know started this week and uh i mean i go to bed right now i mean i'm in bed at like 755 jeez i'm not kidding well because anyways i put them down and i'll see it takes like it takes so long before she falls asleep and then i'm like you know what i'm gonna go to sleep now i love that for you man i do too geez i'm getting my second gym session for the day and at nine or ten i'm not even kidding you i'm trying so hard to flip that switch yeah it's it's hard you should be i mean honestly you guys is the best sleep time like between 10 p.m and 2 a.m does that sound about right where you're getting the best deep sleep it's when you're getting deep the most for sure that's also when at least in chinese medicine that's also when when liver which which to you know the liver does everything i mean it's well that's what the insulin resistance is predominantly having and that's a good point too is like these hours matter it's not just about the hours the the time of the day because of the darkness and our connection with light and the lack of it are so important and something that we talk about in the book because this is something that josh brings into such a passion for traditional chinese medicine.

32:11That it's just, that's what these experts in TCM over thousands of years knew that these specific hours were associated with these organs. And now research is just catching up with this, right? And we don't even know the half of it in our hubris of modernity, how these, it's not just the hours. And that's why the shift workers that work the graveyard turn, yes, they have to make the best of a not ideal situation, but ultimately nighttime is the best time to be sleeping for so many ways. It's a counterfeit to be sleeping during the day. Yes, you have to do what you have to do, but it is not just the hours, but the time itself.

32:48One of the patterns that I see in a lot of patients, I'm sure you do as well, is the 3 a.m. wake up, like the 3 a.m. and then have a hard time kind of falling back to sleep after 3 a.m. And that's the cortisol, the reverse curve. It's like, okay, well, your body is so cortisol-driven and that your body's like, okay, well, I know we got a lot going on. It just starts, it starts peaking way too early. So if people are waking up and that actually in Chinese medicine, they call that liver chi stagnation, but it typically is caused from, yeah, just people that pack their schedule from the moment they wake up till the time they go to bed.

33:25And they just are always like trying to achieve and win. And eventually just living in a sympathetic state with not enough parasympathetic, they'll start to have the 3 a.m. wake up call. And so that's a sign of high cortisol. And that's something that then, you know, it's at the root of a lot of problems. It is. What would you recommend for somebody that's doing that like 3 a.m. wake up, can't go back to sleep and going to bed at a good time, you know, 10, 11 o 'clock. If that is a cortisol problem, what are some practices or things they can do to make a change that's non-medicinal? I would say that neuroendocrine axis, the intersection between the nervous system and its communication with the endocrine system or the hypothalamic pituitary adrenal axis, what Dr.

34:09X was talking about, the what's my nervous system saying to my adrenal glands to release his cortisol. Someone being constantly stuck in that fight or flight, freeze, fawn, sympathetic tone like Dr. X has talked about, we have to be supporting vagal tone. This person almost always has poor vagal tone. and we talked about the gym a moment ago, well, if someone's biceps or core is weak, they have to strengthen it. This aspect of their nervous system is weak. The vagus nerve, the largest cranial nerve in the body, it's the root word, wanderer. It is responsible for that resting, digesting, optimal REM, deep heart rate variability, all the things we want to feel grounded and get good night's sleep.

34:50That part of the nervous system is weak. So we need to strengthen it and do some vagal toning. So there's lots of ways to do vagal toning, but I typically have telehealth patients pick something active and something passive. So something active is something that you actively are doing. It's a practice that you show up. It could be breath work. It could be gargling. It could be meditation, journaling, because this has to do with stress and trauma. You know, yes, it's currently stressed, but journaling is a great way to sort of somatically clear out any stress. Some basic, you mentioned not medicinally, like magnesium can be a great tool here.

35:27Things that are supportive of the parasympathetic. And then something passive, I like transcutaneous vagal nerve stimulation, like the devices that you wear on the ear or neck that kind of are kind of an e-stem on these auricular branches of the vagus nerve to tone it. So actually our CEO over here, Adam was telling me, I told him, I'm like, get this device. And he's sleeping better. His HRV is improved. Neuropod or what do you have him doing? Pulsetto. Pulsetto. So Neuropod and Pulsetto are my two favorites. I've used Apollo Neuro, which I use frequently and Pulsetto were the ones that I've used too.

35:59Apollo Neuro is great too. It works differently because it's oscillation in the bone, but it's similar mechanism. Yeah. It's working on these different pathways of toning the vagus nerve, the parasympathetic. So start there, but you have to be consistent. It would be like doing it once and saying it didn't work would be like me going to the gym once and saying, well, that gym didn't work for me. Right. You have to tone something that's weak. I'll tell you, I had a, by the way, in Chinese medicine, they have a formula for increasing vagal tone. And it's called the wonder formula or the free and easy wonder formula because it's all anyways.

36:30So you take your point with what we call the vagus nerve. Yeah. But we had, you know, Josh Radd, I had him on the show. Yeah, he's great. And he had told me, he said, you know, I have patients gargle if they have constipation, which again is a vagal tone issue, has them gargle for two minutes every hour on the hour. I love that. And I was like, I'm going to try that. I went home and did this. And I was blown away. And I can tell you, do this. And at first, anyways, I tried to do the full two minutes. I realized, okay, no, I need to stop and breathe out of my nose some because I could not. He was drowning himself.

37:05in the kitchen. So what I tell people to do, gargle 30 seconds, breathe for 10 seconds, gargle 30 seconds, but do it for two, two and a half minutes. Difficult, probably. It's a little difficult. Is it a long two minutes, Dr. Axe? I would say it's a long two minutes. Let me say this. I mean, I was blown away at how much I could just tell. I just went right into the parasympathetic. That's cool. It was unbelievable. I mean, I've done breathwork and breathwork is great, but I truly think gargling is the fastest single way to get yourself into the state. You can't just do it for 10 seconds. I think you got to do that full two minutes, but it's incredible.

37:42And it's like this is just free other than your time, right? So that person that wakes up at 3 a.m., that's what they need to do. It's a sign. That's a check engine light. That 3 a.m. wake is a check engine light that their nervous system's ready to go because what's happening there mechanistically is that cortisol is supposed to be increased in the morning. So that's normal. It's happening a bit early. and then what's happening to cortisol is coming up, glucose is being released from the liver and you're waking up. Your whole sleep-wake cycle is a bit too hypervigilant. You're like, okay, yeah, you need that to happen, but not at 3 a.m.

38:15Like calm down a little bit. So just regulate to kind of an adaptogenic type balancing approach, maybe that happening not as extreme at 6 a.m. and waking up refreshed. Reading a book is another good way to do it. Just like reading, it grounds you, it censors you, not looking at a screen but reading I was gonna say not an e-reader like a real physical book yeah so I want to stick to the neuro side of things right now and admittedly I did 15 some odd years of nothing but fitness nutrition not understanding the total control that the mind has over every single thing that we do and and I and I tell people this look at some of the best athletes that we've ever encountered Kobe what was it it was not Kobe athlete it was Mamba mentality why was everybody so scared of Tiger Woods could he put the fear into everybody because he was so mentally strong that he knew he was going to to whoop you when it came down to it same with Jordan so it's the mentality aspect of it and likewise the people that fold under pressure they're the ones that never got elite that had all the talent same thing with with body right so like you guys are saying cortisol spikes well there's a lot of stress and a lot of things going on internally that are caused by that i did a very very severe nervous system reset and what did you do it was with dr sean drake and he called it soul surgery and this is god plays a big part in this treatment in this therapy and i i challenged myself and i said you know what for some reason you want to be compassionate you have it in your heart and it's not coming out you're you're stoic all of a sudden and you don't want to be you're super irritable but you're eating well you're training you're doing all these things what the hell is wrong with you you're spiritually good you're praying all the time why are you doing this why are you so unable to stay focused and why are you not resentful but just kind of angry things that aren't who you are so what i did was i went and sat with him and he was able to pull all of these different traumas out of me or things that bothered me that i don't think about i didn't even know they were there and they were hidden inside and i was able to do this through like the the breath when i tell you the breath work i mean i'd have to sit and show you this was so intense it like holotropic or it was deep deep and then like heavy and then it was with sounds and vibrations and then there was a lot of connection with god and me opening up my mind to be able to hear him talk.

40:50Because what happens is noise, all of this noise and distraction. And I don't know where the hell it's coming from. I can't focus. Even when I'm reading scripture, my mind is like, it's soaking it in, but not fully. So I was able to release this. And once I was able to do this, I just developed this deeper appreciation of everything. Everything my wife said, it was like, ah, you know, I appreciate that you're taking the time to do this, not, man, you're saying this and it's being irritable for no reason. My mom would say something and I'd just be like, man, stop, you know? And instead now I'm listening.

41:27Oh, I appreciate the conversation. Or for instance, I would do this. Oh, I have to go do this interview today, or I have to go do this. And now it's, man, I get to, I get to, I get to do this. Wow. And that just shows you this, like someone's heart state and their mental state, how that impacts so many different things, right? Yes. Because if you're in that dysregulated state, how we show up to the world, that shows up in how you, the foods you eat and how you treat people, how you sleep, all of those things. That's really profound. It is. Was it just one session that you did? No, I mean, I have had to refresh and I started to do this in the morning where if I don't get up, do all my prayers.

42:07So when I get up in the morning, my morning routine is I read my scriptures, like the morning scriptures. I'm Catholic, but if you're not whatever it doesn't matter just read right yeah then i say a prayer over my wife then i you know say i go shower shade but i'm saying prayer while i'm doing it then i do my walk and then i go do breath work then it's time for meetings and you know what if i got a meeting and i'm sorry like i have to push it back because i have to do this or i'm not going to be right and i'm not going to be good to you myself or anybody else and i think the important thing that i'm trying to stress here is get your mind right first before you start your day so it's so true yeah I mean, the Bible says that.

42:43I mean, from your heart, things flow from there, right? It's like everything flows from there. Yeah. Yeah, I totally agree. I mean, one of the things, you know, I think Will and I both feel really strongly about is dealing with past childhood trauma and using faith-based medicine. I mean, I see it constantly where I think anytime I have a patient who, let me just say, at least 90 % of the time, if I have a patient and they start seeing some results, but then they just hit this plateau. I think the most common thing, especially if it's been for a long time they've dealt with an issue, there's a childhood trauma that's just never been dealt with and that's just continually on replay.

43:22I'm not smart. I'm not pretty. I'm not pursued. I'm not loved. I'm worthless. I mean, there's something there that's feeding the fear, the anxiousness, that overanalyzing every last thing, the upset, you know, whatever out of balance emotion there is, there's some sort of trauma or just not knowing, you know, there's, I say this quote constantly. So my audience will have heard me say this before, but my favorite quote in the world is an AW Tozer quote. And it's something like this. He says, what you believe about God or what you think about when you think about God is the most important thing about you.

44:02And so, because you think about like, if God is like an old, you know, scary figure, that's just judging you, or he's distant and really doesn't care or he's benevolent. He's just thinking about you every moment. And it's like, if anyone has kids, like my daughter, I think about her all day. And she's doing swim team now. I can't wait to go and watch her and help her. But if you believe that God is like that, interacting in your life and constantly working things out for your good, what that does to your state is just crazy. And so all that being said, I think that there are so many things that are spiritual, that are in the past, that have never been dealt with.

44:40And then to your other point, and I think if you can, and the number one way to deal with those things is going to the Bible and following the things the Bible says. It's praying and first connecting with God. It's confessing any of your sins, anything, you know, getting that out there, having other people pray for you. And it's just living rightly. But then also writing. Yeah. I mean, the studies on writing for overcoming anxiousness and fear. I mean, it's probably the most powerful therapy in terms of like an exercise you can do. And then part of that forgiveness, the other part is the part of the confession.

45:15Like after that is like forgiving others because the bitterness and rage and like what that does to our sympathetic tone and then forgiving ourselves for things that maybe we did intentionally or unintentionally. The so important part of that whole, yeah. It's all there. It's all there. I mean, surprise, right? god knew what he was talking about we have such a hubris again arrogance today that it's sometimes it's the stuff that we just overlook because we need a randomized control trial but now the great thing is that the randomized control trials are substantiating what god always said not just in this circumstance but many others you know there's the the parable of a sower in the bible and that somebody's sowing seeds and that you know it either falls on uh you know hard ground and it can't get get into the soil or it's uh you know there's a different but the one that stands out to me the most reason i'm bringing this up is you mentioned busyness i think in in the modern day that is the one that it hits people the hardest is that these weeds go up and choke off the plant to where it cannot grow and flourish and so like i just think about my home like this morning like i was gonna have a little bit of quiet time and my office right now is not set up like i can still hear everything and i've got dogs barking i've got my two-year-old like just screaming she's got I've seen got a wiggle bike.

46:33She's flying through the room. And I'm like, you know, I don't know if it's possible for me to get like just a quiet moment. But this is why Jesus woke up before the sun came up. Now, you know, he had an early bedtime, I'm sure. He's going to bed at your time. Yeah. But again, that quiet time and that stillness to hear and to actually let your spirit rest and to connect with God. And that's important. So what I typically do now is I go for a walk. Yeah. Because that's where I can typically get that. And that's an interesting point because that 3 a.m. that we talked about earlier, the context around that's so important.

47:08Are they waking up at panic, heart racing, and they can't fall back asleep? I've had some telehealth patients over the years, when we improve vagal tone, nourish the body with food, deal with all the facets of that would regulate that neuroendocrine axis, sometimes not maybe at 3 a.m., but maybe 5 a.m. they'll wake up. But they wake up refreshed. They're not anxious. When we track the REM deep sleep in HRV, it looks great. And research shows that even if you don't have all like 12 hours of sleep, but it's great quality, let's just say six, eight hours of sleep, that may be the body just being balanced the way that God made it.

47:47And you do have that time in the morning to like go and like walk, get out in nature, put your feet on some grass. So that's not always a bad thing. I don't want to pathologize early mornings because to Josh's point, It's one of the best times to connect with God in the quiet, in the stillness, before anybody else is awake for you to do amazing things. Sometimes people are freaked out by that. I can't go back to bed. It's five o 'clock, 6 a.m. Maybe it's just time because you've improved. Your new normal is you are regulated and you get up early naturally without an alarm. Yeah. I got a new patient for you because my mom does not listen to a word I say.

48:19What's your mom's name? Nancy. Nancy will listen to us. Yeah, that's what I'm saying. I'm going to send her to you guys. You guys have a smoother tone than I do with her probably. Well, sometimes it's the messenger, not the message. That's exactly my point. Yeah, yeah. Okay, so touching on a couple of things that you guys said. One, in the Bible, God made his points in the whispers, in the breath and the whispers. And when they, there was a thing I just read with Elijah when he went to the mountain and there was a storm and there was the thunder, but then that was the whisper from God that was the present message.

48:53And that resonated with me because it was like a direct punch in the gut of you never block out the noise i pray well but i don't listen good you know what i mean and welcome to the club i think we're all kind of hard-headed but but then it came to the point of if you were having a conversation with your wife would you talk the whole time and never let her speak yeah so if you're talking to god and you're sitting there talking the whole time shouldn't you let him speak and i've been trying to implement that into prayer time too so good so i sent you guys um last week a speech that i gave i sent you a clip of it really so good such a good talk and i and i this has nothing to do with me but it has to do with the thought behind the speech i now am on a mission everybody wants to talk to me about peptides and hormones and everything else that the juicy topics of the day which i am more than happy to discuss and they play a certain role in health but foundationally and this is what i want to talk to you both about i have a foundation and my belief set and when i go speak this is what i'm talking about and i guess the conventions are too good for me if they don't want to allow me to speak on this which is fine i'm not going to stop and it is mind body but it's not mind and body spirit it's mind body and god and that connection that i have found to align full health because we can nourish ourselves with knowledge we can nourish ourselves with foods but if we don't nourish our soul we will never be cellular health we will never find the right nutrition plan we'll never find anything we're going to be chasing something forever and i have found once i am able to get people to connect with god in one way or another and even if it's just hear me out let me get into your heart just let me let me let you think about it even if you're the biggest atheist on the planet non-believer hateful whatever let me just get in there and you start to think it starts to change the way that we move internally which then allows inflammation to go down my big point was and i asked the crowd this and i said this is a rhetorical question and i'll wait how many angry negative people do you look at and go wow they're the epitome of health let me check their blood panels and i bet you anything we're going to see a lot of disruption on blood markers so i say there's a lot of knowledge a lot of people that have a lot of brain power with science and all of the things that we're talking about but we carry oh i i believe and i don't want to toot my horn this is what i pray for is the wisdom aspect is what carries us that's what makes us really know i know a lot of people that know so many facts and studies and everything that don't know the first way to use it in fact use it to hurt people right and hurt themselves so that's why I say when you get connected with God, you understand wisdom.

51:37You understand Holy Spirit messaging. That's where you speak. That's why I always, when I go do something, I don't speak off of scripts. I can't because it's whatever's coming out of me that I'm being fed. I always go into something with a plan that somebody sends me and I can't stay on it because I believe that when I go in and start asking and teaching, it's what was supposed to be asked. You know what I mean? And so my question to you guys is, do you believe in what I'm saying? Because for me, it's like, Well, when you connect with God, gratitude comes first. When you have that gratitude, you're able to appreciate everything and then deliver.

52:10You can be healthy. When you give to others, you get back tenfold. But when it's all about Dylan, Josh, Will, and all of this, we don't get anything, man. It's unfulfilling, and then it trickles down into your health. Yeah, I agree. Go with Josh. Sorry. Sorry, I get going. Yeah, well, I think there's a few things there. I think, you know, there's two main things I'm thinking of. One is kind of even a little bit of a theological idea here, and that is, it's interesting, I don't know if you guys know this, but in some churches, they read God's Word first, and then they pray and invite the Holy Spirit.

52:44In some, they pray first, and then they read God's Word. Because some, if you're in more, let's say, charismatic circles, they put a greater emphasis on the Holy Spirit. If you have more of, let's say, a Presbyterian, like a Reformed church, it's a little bit on God's Word. But all that being said, I think it's very important that you're kind of doing both to your point with, should you prepare for a speech or let the Spirit flow through, let that lead you? And the answer is really, you should be both. I mean, nobody's going to give their best speech typically if they're not prepared and have some level of study and understanding.

53:12But also having a level of just not holding on too tightly, a level of looseness to let God work, I think, will lead to the best outcome. And so I do agree with that. And then also to your point, you know, I mean, statistically, clergy, people that are professional in professional ministry, they do live longer. And then also there's plenty of studies about religious attendance, people living longer, having more peace, more happiness. I think this goes back to something I mentioned earlier, and that is your view of God, your relationship with God. If you know that God is working for you, if you know that you're going to live for eternity, there's just a greater level of peace with that, right?

53:50Knowing that I don't have to do it all. I mean, one of the things Jesus said is, listen, my yoke is easy, my burden's light. And that's like, whoa. I mean, and honestly, for someone like me and you guys who are achievers, we want to change the world. We want to run to win the race. There's also an element of, yeah, but part of the race was already won in what Jesus did on the cross in the ultimate race. And so all that being said, there's a level of like, this is true in sports. It's true in academics. It's true across the board. You want a level of understanding something's really important. But also, if you believe that everything's relying on you there's an element of anxiety that actually starts to there's this bell curve of performance there's actually a bell curve on this is you want to be very focused and know this but also if you feel like it's all on you your performance declines yeah there was a harvard i think it was out of harvard they substantiated what dr acts just said that people that had a regular faith practice and community is part of that but also like community with other people, but community that you have with God, 33 % decreased risk of all-cause mortality over a 16-year period, I think it was.

54:57Decreased high-sensory UC-reactive protein again, that inflammation marker. People don't realize that. But yeah, I love that way you said it, mind-body God. But it has to be beyond this rote list of things that you do. Going to church by itself doesn't do the thing, right? It has to be a relationship. It has to be meaningful, not just checking the boxes. So, and Dr. Lisa Miller from Columbia, she substantiates this as well. Like changes in the brain for people that have a faith practice. We have greater resilience on average, right? We know, yes, the small, like the things in our world matter, but we have perspective on the ultimate things that matter.

55:36If you start going down lists of virtues, like the important ones that are spoken throughout the Bible, and then you start to look at it. So I started to look at it from different points of view. So I sat and read the entire New Testament and I thought to myself, okay, I gained a lot here, but it's just, it kind of just revolves around love. And I, so it was embedded in my head. Then I started to look deeper. And this is what I want to tell people. You know, when you watch your favorite movie, 20 some odd times, you always find something new in there that you didn't see. Well, you just brought up the yoke and the burden.

56:07And I read that 50 times and never knew what it meant till like a month ago. And then I got the real interpretation of what that actually means. It's saying, you know, here's my laws, but they're going to be very easy for you to follow if you love me and you follow me. And I grasped and understood. So then I've been able to grasp and interpret these virtues. Well, look at them. First is faith, hope, and love, right? So these are key integrative practices in our life that are going to bring the most joy and happiness and peace. But then I got into the knowledge and wisdom, but then it's endurance, perseverance, temperance.

56:40So how do we relate these to everyday life well you need to have fortitude and and the ability to overcome temperance you need to have some self-control overindulgence and eating and then whatever else bad practices you have drugs alcohol whatever i don't know whatever it is but you need temperance to overcome that you need to have perseverance i mean i've had to have some severe perseverance for mistakes i've made but that goes in general for everything that can be the smallest thing of the day you got to overcome just something small i mean just on the way here i was ironing my clothes in a hotel room i get spilled water all over them and started to get angry and then thought man just get the blow dirt out and blow them you'll be fine they'll wait yeah you know but these concepts in the bible that are misinterpreted misconstrued misread are the handbook to life if you just read them and understand them there's an answer to everything in there yeah and that's showing up on a cellular level and science is substantiating that now that we have 30 plus trillion cells and they're all eavesdropping on how we talk about ourselves and other people.

57:42And there's a resonance there, right? I mean, their cells feel unsafe and both physiological, physical things like foods that don't love us back, environmental toxins, that makes our cells feel unsafe. But our disconnection from God also makes our cells feel unsafe, which is why studies are now showing why people that have a deep, rich faith life tend to live longer. Look, we can't control everything. So we're not saying that if you have a faith, you're going to like everything's going to be good, but it's just a component to how lit how on a cellular level we're meant to live yes and that's the thing i i'm also not saying oh i'm perfect and i wake up every day full of joy and happiness and everything but i will say this when i take the time to pray and i sit back and think about how many blessings i have as opposed to the things that i'm whining and complaining about then i come to this quick recollection of hey man like you need to just chill and one of the things in the bible that It'll say pray constantly.

58:36And I used to think in my head, man, I'm not sitting here and praying 24 hours a day. But what it did bring out in me is little moments where I feel alone or something's bothering me. And I just say in my head or say a prayer and I talk. I never feel alone anymore in any aspect of my life. And I found myself talking to God more than I even talked to my wife throughout the day. And it's actually quite beautiful because you don't even realize it. When you know when you talk to somebody like we're talking here. I mean, I don't know. We've been going an hour. It feels like five minutes. But when you're in that, you don't even realize it.

59:07When I talk to God and I look and sometimes I'll look and I'll be like, man, there's 20, 30 minutes. I better get rolling here, you know? And it's like, you don't even realize it because it's so valuable. But that time is spent so well and it impacts everything you do. Then it helps you cellularly. Then it helps you focus. So I guess my point is saying, no, you're not. There's no such things as rainbows and unicorn 24 hours a day. but it's going to enhance your quality of life, not only for you, but the people that are around you. Yeah, absolutely. It's without a doubt. And it's, people forget it sometimes they were looking for the next biohacker.

59:42You said like the next peptide. Sometimes it's like, maybe just get your relationship with God, right? Yes. Your relationship with the present moment, right? That's really important. That's why I say foundationally, we set that. And once we have the foundation, then we can move forward. So, okay. I want to go over a few different things that are going on right now with you guys. I would like to get into some peptide-related discussion, but I want to go a little bit deeper. All everybody wants to talk about is GLP-1s and people, when they say peptides, that's all they think, literally. And it bothers me because I've spent 15 years when I first found them studying them.

1:00:18Do you guys have any feeling on our future here with where we're going to go? Because I look at peptides and I'm showing people, look, there's something for ejection fraction here with SS31 for your heart. We got mitochondrial, MOTC, Solank and C-Max are helping with the stress and anxiety. Do you see a future here or do you see, because I am in the trenches, I see people that are trying to take advantage of this, sell them everywhere, compounding pharmacies that don't know how to compound anything that are just popping up. Do you see this broad spectrum of people shilling and taking advantage of the system or do you see alternative medicines and therapies.

1:00:58Will's had him on before. I had Brigham Bueller on my show, and he's really a peptide expert. I mean, he went a few weeks ago, three weeks ago. Actually, we had to change the podcast date because he was scheduled to come on my show. And then he had to go to Washington, D.C. to meet with Robert F. Kennedy Jr. and testify in front of the Senate. And so he was just on. And, you know, he thinks that it's going to keep getting passed through. He said that one of the problems is a lot of these senators, they didn't. They just didn't know the science. And so, I mean, it's so interesting. You wouldn't think this would happen with professionals, but some of the things he was getting around is rather than actually reading some of the documents, one of them just had AI interpret it for them.

1:01:37And then they shared something and they said, well, what you're talking about, that's like an Olympic drug that was banned in the Olympics. It's not even a peptide. I mean, it is just so, so awful. For the whole world to see. Yes. And so all that being said, I think we're going to continue to see them pass through, become legalized. Because, listen, there's a choice. So I recently saw on Instagram somebody post, this is a doctor who, you know, his name was discredited. He was found in the Epstein files. People used to listen to him. And now many less are because there's just so many character falls and issues there.

1:02:11But he came out and did this whole thing on GLP ones are safe. Now, it's before he didn't say that, but I found out he has a tie to, he owns a company that's about to sell that's creating GLP-1s. So, but again, by all that being said, and then he was saying, well, you know, a lot of these peptides aren't, you know, there's proven, there's no proven benefits. There's no double blind, you know, placebo trial studies. Now, here's the thing I will say, and here's the thing I talked to Brigham about, is that when I worked as that personal trainer for four years, one thing I noticed is bodybuilders are the most obsessive people I've ever met at tracking.

1:02:49I mean, they changed a half a pound of body fat. I'm going to wash. I remember there was a woman who was doing this who I was friends with, and she would wash her chicken breasts to make sure there's no salt on them. So to my point is they are absolutely meticulous. And BPC-157, an example, you think for the past 20 years, bodybuilders haven't been using that and actually knowing, oh, I injured my shoulder doing shoulder press, using it and knowing what works and doesn't work. So the reality is maybe there's no double-blind placebo trials or not many, but there is so much anecdotal evidence for numerous peptides.

1:03:26And the reality is they do work. I've noticed it physically. Will's noticed it physically. We've got so many people that have used it. And so, by the way, on his thread, when this doctor posted this, basically, there were hundreds of comments of people saying, actually, it fixed my shoulder. I mean, that was pretty much all of the comments. So all that being said, I think that it's just a matter of time. Now, the government needs to make a decision because if you don't make it white market, if you don't make it to where, hey, you can go to your doctor and they can prescribe it, or as long as people can get it, they're going to be happy.

1:03:59They'll go through some of the channels to get it. But if you make it to where even functional medicine practitioners can't prescribe them and recommend them, people are just going to go to the gray and black market. And then who knows what they're going to get because there's a lot of stuff that's tainted out there. In fact, I read one story where BPC-157 was tainted with testosterone. This guy lost his license. I mean, this happens all the time. So the reality is you want to make sure you're buying from a United States compounding pharmacy when you're getting pedagogy. They have transparency and purity.

1:04:26Yeah. What they did is just shoved it underground. I mean, it's just, yeah. Yeah, the Biden administration in 2023, when they just based, they grew the market even more under this sort of shady gray area research only model. So yeah, hopefully there is, we can bring it to the light and oxygen can be infused into the market. And I think the truth is oftentimes somewhere in the middle. I think the one side that on that, it's also with the natural health world, it's just kind of controversial for us to even have this position because some people are like, you, this is like scary. We shouldn't be doing peptides at all.

1:04:58like the super crunchy wellness, purist zealot that we love. I mean, they're our friends too, but they're very anti-peptides. And then you have the other side that's like peptides or the, you know. It reminds me of the conversation around like, you can eat butter and tallow all day, every day, and there's no issues. And it's like, no, that's not true. That's not true. Yes, exactly. So yeah, of course there's caveats. Of course not everybody should be doing all the peptides but the truth somewhere in the middle like the dose the person the purity all of these things matter these people kill me and i'll tell you why this extremism that goes so far yeah and i always tell people i'm not going to say the exact verbiage because there's some cursing in there but i always tell people look i'm not your dad do whatever you want if you want to take all the vaccines in the world have at it don't tell people that they have to do something same with peptides man if you don't like them stick to your conventional medicine or whatever it is that you do do whatever you want why are you so angry and so worried about what everybody else is doing looking for alternatives nobody's telling you you have to do anything but i will say this and i want you guys's thoughts on this so i always call conventional medicine the real non-conventional because i i look at something that is taken naturally and generally altered methylated whatever you want to say.

1:06:18And so that's why I call it non-conventional. I would say conventional medicine is more along the lines of natural herbs, traditional Chinese medicine. It should be primary care for, it should be the primary for sure. Yeah. That's what I was curious, what you guys' thoughts were on the negativity, the views that people carry. And why do you feel, because for me, when I see all that negativity, you know what I see? Poor health. That's the first thing I see. Yeah, I think the thing that I have a hard time with is that, I'll give you this with the cancer industry as an example. There is no doubt in certain clinics in Europe, there's a few in the United States, but that cancer treatment is being done much better than what the conventional system is doing.

1:07:06But what the people in the conventional side will say, I'll give you an example of this. Like I work with a cancer patient probably every week, okay? And it's cancer support. And what we'll do is I'll try and lay out what is the ideal integrative treatment. Whether they decide to go and do chemoradiation or not, I'll go through and we do something called an RGCC blood test. It's a Greek test. And it'll tell you, does sulfurine work? Does high-dose vitamin C? Does liposomal turmeric? Does hyperthermia? you know, what are the things that move the needle the most for this type of cancer? And it's a great test and I think really effective.

1:07:41And so I'll take that and I'll lay out a protocol of, you know, here's your ideal diet of what you should eat for every meal. Here's the exact supplements. Hey, let's do hyperthermia because, you know, here, here and here. And then maybe you are going to do radiation. Maybe you can skip the chemo because in like colon cancer, it's typically used as what they call a radiosensitizer to just make the radiation more sensitive. but chemo is even more damaging on the body and it's throughout the body where radiation is more localized. So let's not do the, you know, ideally they'd be better off not doing that, doing the lotus dose of radiation, but they want to do something.

1:08:14Okay. You can do that conventional, but let's do all of the natural therapies we can. And what a lot of the oncologists will say now, by the way, some, some of them, they're becoming more and more progressive of saying, Hey, I think that'd be a good idea to do this, but most of them will not move off what the current treatments are because those have been established for the last 60 years. That's what they get paid for. But it's not the best for the patient. So I get frustrated that, like, listen, there is a better model out there. Let's work together to find out what it is. Yeah. Yeah. I think for most of not just cancer, but all chronic disease, it should be both and not either or.

1:08:49Like, what's the most effective option that causes the least amount of side effects? And you're right, this both sides, because then you'll have the health, like the health purist side with cancer specifically. It's like, I'll never do chemo, never do radiation. What's like, well, what's the context of it? What does the data show? Maybe it's both and. So there's so many examples of that. I think people that are against, the question was like people that are still against people in functional medicine. They're on the wrong side of history. I mean, mainstream institutions like the Cleveland Clinic don't open up multi-million dollar functional medicine centers because it's woo-woo and quackery.

1:09:23Because the data speaks for itself. So people are still like, it's us versus them. Where have you been? I mean, I've been doing this for 16 years. This is not radical. Getting people healthy should not be offensive. If it is, look at your heart. And I can tell you 20 years ago, 99 % of doctors, I'm serious about this, would say you cannot reverse type 2 diabetes. Oh, yeah. I would get phone calls saying I was going to kill people. How dare you? Yeah. They literally felt like it did not matter if you ate a Snickers or an apple. Type 2 diabetes, not type 1. Type 2. We're talking about type 2 here.

1:09:56And then now it's probably more like 50 % of doctors do believe you can reverse it. And 50 still don't, which boggles my mind. But we have come so far in 20 years. So far. That's funny that you saw the same thing because it was type 2 diabetes. I'm like, wait, what? Out of all the things, that's offended you? But now you're right. It's just like. Here's what's offensive to me. I was in the, I had a small incident and I was in the hospital for three and a half days in the cardiovascular area. All right. And I had to stay the night. there all weekend and they bring me a menu and this was the heart healthy menu and i looked at my wife and i said does that say chicken effing parmesan and margarine and dinner roll and i took a picture of it i have it on my phone i could show you this is what they have in their heart healthy menu margarine and dinner rolls chicken maybe sugar-free jello or pudding i'm not even kidding you chicken parm and tortellini were on here i mean if you took a fork or knife and just scraped everything off with a chicken meal.

1:10:57Well, I mean, you'd still get the hormones, but outside of that, you know, that's why the United States spends more on any, more than any country. Yeah. We have the shortest lifespan and the most chronic disease. I mean, all you have to do is look at how we're feeding people in the place that should be a place of healing. I know. So my goal, when I talk to people, because everybody wants to live longer, I mean, that you see that everywhere, but they, they don't look at the quality. And I always tell people we should be trying to add years to our life or i mean life to our year you know our years you know not years to our life and people don't understand well we have this lifespan but yeah but how are you living it how do you feel so i guess my question to you guys is if we're looking to enhance quality of life as we age now cellular health i think would be one of the obvious right So I think that that would be the number one thing to address.

1:11:49But let's look past cellular health. I look at markers like, you know, more obscure things, too. I'd like to look at that, too. Like at NAD levels, I started to really study the past year and a half on the importance of that. And that's a whole other topic on flooding people with IVs that we could get into. But I'm just looking at markers right now. What are some other things that as we age that we should kind of look at? Man, maybe we should address this. Maybe we should focus on this. as far as longevity is concerned well i think one of the hallmarks of aging that science recognizes that we talk about at length in the book is gut health i mean microbiome balance and the ripple effect of that i mean when you look at the ripple effect of inflammation and oxidative stress and stress of the bagel tone and the impact that i have so it's a gateway gut Gut health is such a gateway to so many other pathways, a cascade or ripple effect.

1:12:44So I do think that it should be a bigger conversation in the longevity space, right? People can have, you know, they'd be eating great foods. I see this all the time. We see this all the time as people that eat better than the average American, but they have really poor gut health. And that shows you, yes, food is a big part of it, but it's not just about food. I mean, it's about our environment. It's about stress and trauma. is a lot of different things that can impact microbiome health. So I think a deeper, more meaningful attention when needed to get the gut to a better place is profoundly important.

1:13:17I've noticed when I really started to address this, the sleep has been a lot better. The feelings, I feel a lot more satiated, you know, and after I eat, I'm less hungry, honestly, too, which is I'm kind of throwing it back with the training where I was like, man, but I can tell the health is better, right? And I started taking a spore-based probiotic, and that's another topic we could get into later. But there's a lot of different probiotics, and no one knows what they're taking, and they're throwing all these things at there. And, well, I'm taking a probiotic, or I'm taking an enzyme. And I say, well, do you know what's in it?

1:13:53Do you know what it's doing? Because I used to be one of those people, too. So what about you? What do you think, Josh, on some other things about longevity that you would recommend? I think exercise is incredibly important. I met with a patient yesterday, and this is the group of people I think have the hardest time with it. It's probably women in their 50s and 60s and 70s. but I mean, the fastest way you can increase mitochondria is through weight training. I mean, it's not even close. I mean, because you have so much mitochondria in your muscle, you know, outside of your brain and heart, your muscle, I mean, that's where you're the most mitochondrial dense.

1:14:33And so, yeah, I mean, anytime you can add on muscle mass and then of course, what that does to your metabolic health is incredible. So I think for longevity being But now, now here's the thing I want to say. It's just when I was taught to work out when I was younger, it was all about just moving to put on muscle. But also now I've added the second part of don't hurt yourself. I mean, you know, I mean, I had a back injury that was terrible. And part of the reason that led me to this infection was, well, okay, I injured my back doing CrossFit, which was really unwise. It's like, hey, let's do Olympic lifts for time.

1:15:09The more I think about it, the more, what was I thinking? Yeah. What a terrible idea. That's a whole episode on a song. Anyways. Pick up heavy things with good form. Yeah. That's the thing. So now when I exercise, I mean, I was a personal trainer and I know a lot about health and fitness, but I still have a personal trainer. I see at least once a week just to watch me do things to make sure I'm doing them properly. And I found that to be incredibly helpful. So yeah, I think for most people, weight training and then just walking. Yep. Weight training and walking. Zone two, there's a lot of great exercise or resource run in zone two.

1:15:44Yeah. So I think doing those two things together are massive for longevity. And just being like, to your point, not just living a long time, but being active. Like I want to be active with my grandkids in my 80s and beyond that. So I think that's, you know, I'm blessed. I've got my mom, I think is 74 now. My dad's 76. And I just went with them two weeks ago. We were at a lake house in Tennessee and my mom water skied, slalom back and forth, crushed it. my dad went trick now people don't do this anymore everybody switched to wakeboarding but there used to be something called trick skiing yeah so he he literally had the rope around his foot and was doing like 360s 76 yeah wow yeah so my they're both incredibly healthy and a big part of it is they've decided every morning when they wake up they go for about a 45 minute walk my dad still lifts weights my mom sometimes like she's off or on i'm trying to you know she's more like she'll do one or two days a week yeah um but but that's part of the reason why they're still so active and healthy in their 70s.

1:16:42Yeah. And that's, I think, a good point here is that people maybe that are listening to this or watching this in their 20s, 30s, maybe even 40s, they're not thinking about longevity. But what you are going through in your 70s, how you are in the 70s begins in your 20s. You are investing in the rest of your life now. Anyone over 40 will absolutely agree with me on this. That time you sprained your ankle in high school playing soccer or basketball, you'll feel it in your 40s. You know what I'm saying? Because that's the area where the cartilage, the tendons, the ligaments were inflamed or partially torn that were never fully repaired.

1:17:21And you'll feel that. So doing everything, and this is why also, honestly, if I have any minor injury now, I take peptides, I'll do stem cell, I'll do PRP, I'll do shockwave. I mean, I'll do whatever therapy I can because I know I'm going to do something right now to prevent me feeling this in 10 years. Yes. I want to make a couple points on some things you guys said. So the first one, my wife, and I've had this conversation with her, I don't know how many times she comes to me like three days ago. And I tried to be patient because I've already explained this to her. She's like 98 pounds. And she's, we talk about strength training.

1:17:53I want to be toned, but I don't want to gain too much size. And I said, babe, listen to me. If you knew what it takes to hold two pounds of lean muscle in a year, I said, you'd need to double your caloric intake. your weights would have to go bigger than mine right now for you to gain any weight and i say this for women that are scared that they're gonna get big bulky if you understand what it would take for you to get big for the just the food consumption alone and i'm not just talking protein i'm talking calories that you're gonna have to take in to allow you to grow especially as you age just and the supplements or performance enhancers you're gonna have to take too because especially as you get older, it's harder to put muscle mass on.

1:18:34Let me say this. So any women, first off, women shouldn't be concerned about that at all. No. But even if they are, they're probably doing the right, wrong exercises. I mean, if you're doing a lot of biceps and triceps, which you really don't need to do, maybe that's your arms you're most concerned about. But most women should be doing their butt, their hamstring, so posterior chain or general legs, and then shoulders, back and core with compound movements. And if you do those right exercises, you're only going to have more of a V look. Like you're not going to end up looking big no matter what.

1:19:07No, it's just not going to happen. And like you said, training the butt. And then, you know, women carry back here. You know, they carry a little bit of extra back here, even when they're thin. You can do like high, high reps and low weights to get tone. You know, I got torn up. I went on this podcast because I really, I started to do a lot more focus on women that are in menopause and trying to help and understand and comprehend. As my wife started to go through things, And then I realized I am not compassionate and understanding what women are going through at this age. So I really dug in here and I got on a big podcast that was addressing women in menopause.

1:19:41And I was telling them, you have to lift smarter, not harder as you age, just like you said, the injuries. And I had this woman telling me, oh, you don't lift in baby weights and you're not going to gain anything. And I said, well, first of all, I didn't say lift in baby weights. And second of all, if you're injured every other week, you're not making any progress. So you got to prioritize. The rest, like we said, but lifting smart. We're not getting younger. Injuries accumulate and it's easier to get hurt as you get older. You guys know that, especially after we've had injuries, like you said.

1:20:12So I implore people, don't go into the gym, A, worried about anybody saying anything about how much you lift. That makes no difference whatsoever. You're not getting paid. And even if you were, sacrifice it because you don't want to get injured. And two, train for your health. That's it. You know what I mean? Train for your health. When I feel like I looked my best, ate abs and just ripped to the gills 4 % body fat, I felt my worst. I was the most miserable I've ever been. You can look phenomenal, and I mean phenomenal, with no drugs, no steroids, no any performance enhancements by just eating right, training good, sleeping good.

1:20:49That's it. That's it. So I just wanted to make that point. Now, I want to do a little bit of diet questions with you guys, especially because this has been it's getting so polarizing now. The angry diet advice that I see where people just get so pissed off. If you don't follow keto seven days a week or you don't follow carnivore, if you hate vegans or what? I mean, it's just it's like everything that people say. Here's where I'm at. I've been studying nutrition since I was 11 years old. And I've been through, we talked about this, the fear of fats and all these misguided information. My care is metabolic flexibility, which depends thoroughly on your age, your activity level conditions that you might have.

1:21:31I am one of those that find a keto to be a tool, carnivore to be a tool, vegan to be a tool, but not a lifestyle. A lifestyle is being flexible metabolically. And being metabolically flexible means you might have a high carb day one day. It's good carbs. It's healthy carbs. you might have a really high protein day i try to prioritize fats but i don't go crazy yeah i want to know you guys's views on these hardcore seven day a week keto seven day a week vegan like these hardcore extreme diets because i find the restriction actually causes you more problems down the road but i want to know from you guys hey have you said have you seen the snl skit where it was like a maha snl skit and where oh you guys gotta watch this it is hilarious and so they have this jordan rubin texted to me like right when it came out and i watched it but there's there's somebody laying in a hospital bed and they're like laying down just like asleep and they said uh you know they say something to the to the like of um oh he's a vegan he goes oh pull the plug you know but so so here here's my opinion on this i i think you know and will likes to use this term it's a great term it's bio individuality i mean it's it's a it's a term that really correlates with personalized medicine.

1:22:44And I think some people need to be on a keto diet. Maybe it's 3 % of people. I don't know. I don't know the exact number. I had a cousin who was diagnosed with glioblastoma. And the literature is incredibly strong in the favor of following a ketogenic diet for life. So there's an example of that. But I don't think most people should be following a ketogenic diet. I don't think most people should be following a carnivore diet. I I think we're omnivores. I think there's, you know, in the Bible, you see we ate plants. And then in Genesis 9-3 or 6-3, you know, God says, hey, you can eat the things that creep and crawl on the ground.

1:23:24And then we have the food laws with Moses. And then, you know, and then later on, we see Paul to the Corinthians church saying, whether you eat, drink, or whatever you do, do all for the glory of God. So there's a sort of progression in the Bible, too, of in terms of like what we see dietarily. But overall, I think everybody is an individual. I'll share this. I don't do well with high fat. I don't even do well with probably high moderate. I do okay with moderate to low moderate. I do well with like a tablespoon of olive oil, tablespoon of coconut oil, filet mignon or whatever it is that's good fats in small to moderate amounts, I do good with.

1:24:02Part of the reason is that like, this is from Chinese medicine. When I deal with stress, I deal with it in my liver. And so my liver is the most stressed organ I have because the emotions I feel I tend to deal with are like frustration. That's all liver. So different organs have to do with different macronutrients. I mean, the liver deals with almost everything, but I mean, it's definitely dealing with a lot of fat in the gallbladder. Whereas, you know, your stomach is probably having to do a little bit more with hydrochloric acid and breaking down certain things like protein. So a lot of it has to do with, again, but my whole point here is it all comes down to the individual, what your macronutrients should be.

1:24:36Yeah, and even within these camps, there's so many different ways to do it, right? I mean, there's so much ways to do the ketogenic diet. Are you eating just anything because it's a hashtag keto and just it's low carb? Like you're talking about the bodybuilders, the downing alcohol, like cocaine is keto. It doesn't make it healthy. So it's like, are you doing it in a nutrient-dense way or are you doing it in an inflammatory way? Yeah. Just because it's high fat, low carb. so I just think the context around these conversations matter the context of how you're doing it and then who are we who are we talking about and then like you said is it a tool or is it a lifestyle is it used for a period of time and what served you in this season of your life you may not always need to do yeah like especially if you're building improving metabolic flexibility lowering inflammation improving gut health yeah maybe like diversity variety flexibility is the goal for most people yes I get these people they get so angry and they get so mad if you don't follow their diet i'm like brother do whatever you want this is one size fits none i try to do low carb and i train so i do 90 some minutes of cardio a day and then i lift another hour or two i try to do low carb and i'm a mess and and part of the problem is i'll start to have heart palpitations because i can't hold electrolytes because even when i take them in my body without the carbs is like draining them out and i kept why can't i absorb because i'm eating like next to no carbs yeah yeah you know it doesn't work for everybody i'm i'm certainly not anti-carb now i don't like high carbs and i come to find out that i eat high fat and i just thrive on it i starve myself and i'd be interested to see like if you were maybe you've done this because you're in the space like measuring your ketones you because of your metabolic flexibility you may have be a sort of low to moderate carb and still be producing small amounts of ketones yes i am Absolutely.

1:26:28And that's what you said, knowing your body. I mean, I didn't eat fats for 15 years, man, and I was a mess. And then when I started doing it, it's like, you know. Well, I can tell you this clinically. I mean, everybody that, for the most part, that I personally work with, I mean, I'm very much done. I don't think, when I personally work with somebody, almost every time their diet's different. I mean, it's very different. Or at the very least, somebody is put in a very specific category that's typically proven to help that sort of diet. or Hashimoto's thyroiditis, that diet is completely different or might be very different than somebody with cancer, irritable bowel disease, cardiovascular disease.

1:27:06I mean, a lot of times it's very different foods. Because the way that I like to put together eating plans is not just, hey, this is healthy for you. It's no, what is the single best food for you? So if somebody has heart disease, what is the single best fruit for somebody with heart disease. It's probably going to be, I mean, I could argue pomegranates because of mitochondrial health for that. It could be apples. It could be blueberries. But I'm going to put in there, these are the fruits that are best for this very specific condition. These are the proteins. These are the other forms of carbohydrates or the vegetables.

1:27:40So that's the way that I like to build out eating plans. I know Dr. Will does it very similarly as well. And what we're able to do with our work at the Health Institute is create that bio-individuality of knowing the nuance and context of, and books are great. Like we wrote this book, we're really proud of it. And even there, based on their, what organ's aging faster, they have a different prescription. There's so much bio-individuality, but there's limitations with a book, right? Yes, we put multiple tracks and they're based on their score. There's an assessment to see what organ's aging faster that we adapted from questions we ask patients.

1:28:13but the whole point my short i'm trying to say is on a clinical level we can get a lot more granular and like their clinical case is their book their own personal book instead of this dogma where you're saying these tribes it's like okay what's what loves my body back in this season of my life uh and not compare yourself to other people which you know people in our space uh i mean we probably stress people out sometimes too and so it's important for us to be careful with our words and being mindful of like yes all this is good education but just because you hear about it on a podcast or read it in a book doesn't mean that you have to do all the things i'm trying to work on that myself and i've been stressing to people like look there's some people that i love i call them like really close friends but i don't agree with some of this stuff like scaring people if you guys ever look in the comments see i i look in the comments not to see what somebody says about me it's like what's going on like what's what's going on it's always confusion people going well what can i even do what can i even we're creating a bigger problem yeah we're literally creating stress when we do that.

1:29:10Yeah. You know, and a part of it is messaging. You're absolutely, that's a big part of it is. And, but the other part of it is we need, I, my hope is, is that these longer form conversations can provide nuance and context and people should have discernment. And I think that's part of the problem too, is as a consumer, we just are so bred and trained to like be spoon fed and be told what to do. That's not like a podcast is not the same as a doctor's visit. Like just, you have to understand that yeah and be like okay to have this tournament on what to do and what not to do yes you have to like everything in life's a little bit of trial and error right because we just don't know what i can sit here and you guys can do the same and what we've seen work there's always going to be an outlier there's always going to be somebody that's going to leave a comment or something well this didn't work for me then we got to be aware of that and that's why we have to like highlight that everybody's different it's one size fits none technically but but saying that what i want to talk about is there are certain foods or certain things that are just going to cause problems right so i want to talk about seed oils now because all three of us have a passion about it i just i literally like last week finalized and signed a contract with the the seed oil free alliance which they do seed oil certifications now to to endorse this is seed oil free like the hardcore testing so i mean it's a that that to me i always say if somebody says they don't care about money run because that's all they care about.

1:30:38This is more of a passion project for me because of how I feel. And I feel that this is something that is really getting abused on both sides, really, because people are lying. They're just flat ass lying. And whether it's that's what they're being fed or they know what they're doing about how dangerous they are. And then there's people that go way overboard that just act like they will murder you at the same token now i obviously find a lot of wrong there i wouldn't have joined this alliance but i do want to i want you guys to shed light factually down the middle on what you've seen what you've encountered and what's true and what's false i mean i guess i can start here so you know my my opinion is this i think that gosh this is going to sound terrible i you know some of the no say let me say this i think there are going to people be people on both sides that disagree with me.

1:31:28I think it really does come down to, and I'm looking at this from a Chinese medicine perspective. I think for some people that sometimes certain types of saturated fats are going to be worse for them than seed oils and vice versa. Like in Chinese medicine, when you have something that's solid at room temperature and that fat, it tends to move slower through the body. That's the belief and thought. So I think certain people that are prone to cardiovascular disease, I mean, that's the main thing I'm talking about when I'm saying this, I think that over-consuming butter, over-consuming animal fats is not ideal.

1:32:01Okay. And I think that might be just as bad for them or worse than certain time seed oils. Now, I also want to say this. I do think that when you have the people that are living and dying by the double-blind placebo studies, they're just missing a lot. Because even when you're looking at a meta-analysis that's brought together numerous studies and you're comparing over time, because what they're doing, by the way, if you just looked at it that way, seed oils are going to outperform. I mean, when you just look at the studies, they're probably outperforming saturated fats. But one of the things that's happening is a lot of the studies are counting olive oil with seed oils.

1:32:37The other thing is those people that tend to do olive oil or do seed oils, they tend to be historically, they've been a lot more physically active. I think that's throwing off studies. And I also think when they're talking about the saturated fats are they talking about the saturated fat from from conventional meat yeah that you're that they're making it i don't know burger king and mcdonald's and all these fast food restaurants and most of these studies too are epidemiological as well so it's like causation and correlation are different too it's like the people that tend to anyway sorry for interrupting no no no you're no but that is a massive point and you're 100 right there so the reality is it's like nobody knows yeah like nobody knows for certain here's the thing here's where i just try and cut cut to things just do olive oil all the time i absolutely guarantee you it's like the united nations of fats i feel like most people will get behind it like you know what i mean there's tribes for everything but olive oil is like this utopian kumbaya moment where whether you're vegan or maybe do carnivore people hate olive oil i don't know what do they think you know i can't keep up there man i will say this they don't probably do much of it but i don't think they hated i'll actually say this generally i recommend fruit oils and that's what they are i mean if you think about it avocados are fruit olives are a fruit now people would push back on this one but i like coconut oil too i mean in terms of you're comparing it to every other saturated fat yeah it's the one that impacts cardiovascular uh because of the medium chain triglycerides the least but yeah extra virgin olive oil absolutely is by far the healthiest oil most people can consume and the better the better when it comes to the polypenol like the the xenohormetic, like the stress that that sweet plant went through, like living in this arid desert under the heat with insects like that, the cells of that plant is gets transferred to us.

1:34:23I agree with you. And to your point, I think if somebody has a liver and gallbladder that are just working really well, I think they can tolerate and do a good amount of butter and tallow and just do fine with it. Yeah, absolutely. You know, one thing that was interesting is this is something actually Gabrielle Lyons brought up and I don't know, I understand her philosophy on it and I think she's probably correct, but she said she thinks that you can do a higher fat diet as long as you're, and not have risk of cardiovascular disease, or I'm summarizing part of what she was saying, and do things like butter and tallow as long as the caloric intake stays low or below a certain level.

1:35:00But if you're doing a lot of saturated fat from animals and a lot of carbs and a lot of, you know, and you're in a high caloric intake, that's where the risk, you know, really tips off and goes up dramatically at increasing your risk of a cardiovascular event. I agree with that. And the science, the literature talks about this mixed meal phenomenon too, where it's like, is it, was it the, back to the epidemiological side of it, is it the saturated fat or is it the American meat, like the bun and the burger and the fries and then we blame the saturated fat? Yes. Whereas like this compounded effect of high carb plus high fat.

1:35:33Yeah. That's like, can be an inflammation bomb for sure. Well, I can hear, I can tell you this through blood markers on myself and I can, And I can show you this on how they've changed since I started eating like higher fat. But calories are still on the lower end. So here's how I base my diet. It's kind of like a 40, 40, 20. So it's like 40 % fats, sometimes like 42, 43, and then protein and then carbs. And I have monitored. I do blood panels every three to four months generally now at this point, because knowing what I found out about some plaque in my arteries and LP little a. and my lp little a started at 330 it's gone down into the 90s which i told was impossible um and i do it was in what 300 it was 330 when i first found it and now it's that's very normally between 100 and 95 yeah yeah um and pomegranate juice is one of the things that i do have daily every day that was brought to my attention that that could reverse plaque i'm getting a clearly scan in the next two weeks too so we're going to get a real strong indication so generally speaking And I just started to implement chicken again, finally, after I don't know how many years of being like against it.

1:36:40So I do two days of salmon, avocado every single day, four whole eggs, three days a week, and then some animal fat. So 85 or 93 beef, occasionally 80s. But I do elk, bison, venison, mix them in. I'm doing about 100 grams of fat a day, 220, 230 protein, and hopefully 100 carbs. and all of my markers aside from my LDL and my APOB went up slightly. Everything else, particle sizes down, liver down, everything that was high down, they all came down. Granted, your LDL is going to go up when you have that kind of diet. Grass-fed butter I have every day, but not mounds of it. I'm just cooking it now. The quality improved.

1:37:22Everything, but everything that I have is pasture raised, grass-fed, 100%, not grass-finished. I I mean, I am, dude, I travel with a scale. Like I'm Mr. Way, everything like you were saying, and everything is pinpoint. My life is lived around regiment and precision. So I monitor everything and I know every single number in my head. I have a photographic memory. So I know what I see on myself, but I don't want to say that for others because other people aren't on some of the medications I'm on or don't train like I do or don't have the same kind of like background that I have, you know, from from whatever I've inherited And some of that I believe in some don't.

1:37:59But the point is, is everybody's different and you only know your own numbers. You can't monitor what everybody's doing. I was just talking to my wife about this. I said, how the hell do I know if somebody's at home doing exactly what they're telling me and eating exactly what they say? And like you guys said, how do I know what kind of beef that is? How do I know what else has been included in there? What kind of condiments they're using or whatever? I don't know. So some of these studies I take with a grain of salt, we need them. but i also i care about being in the trenches and getting real world experience like we talked about this earlier about peptides man i i want to know what all my clients are doing what all the people in the forums i'm at are doing and what their their body response real world data yeah i want real world data to compare and contrast with the studies and i can tell you yeah man these people were 60 years old with this condition and had this so that i could get the outcome i wanted oh yeah you know and that's like the devil's in the details same thing when you google something.

1:38:53Be very careful when you get this AI response and you don't look at the source of where it's coming. It's a really good point because anytime, and I use AI very often for creation. Yeah. And I have to wrestle it. Like friends, I've been writing articles and having it pull certain things, but it's view of peptides is very negative. It's view of, I mean, it's very conventional and some are worse than others. I mean, Grok is probably one of the most friendly towards natural medicine. I mean, Google to me, and probably Google is the most hostile. Probably Gemini is one of the most hostile. Claude is not great.

1:39:32I can get it to where I want. Chat GPT is a little bit more friendly too. But yeah, generally a lot of these AI tools are very, they're just, what they're going to do is, it's just like, they're just going to go to WebMD and CDC and that World Health Organization. I mean, that's where they're going to go to first to pull a lot of their, So I have to go and tell it, I want you to go and pull more functional medicine-minded these journals, and I actually have to tell it what to do. And act like a research assistant. Yeah, it's crazy. I just urge people when you do a search, look at the sources. Yeah, it's easy to just read it.

1:40:06Back check it, consider the source. 100%. Yeah. All right. So what I want to do now with you guys is talk about if you were stranded on an island or whatever, one of those questions, but you could only have five foods that you had to live on. Because you ask somebody this and it's like, oh, I'd want pizza and ice cream. Like, brother, man, you wouldn't want to eat that every day. Only if you were stoned seven days a week. So what kind of foods would be your five? This is what I'm living on. This is what I'm never going to get sick of. So this is off of nutrient density and survival or enjoyment?

1:40:41Either one. Okay, so this has to be well-rounded. Yeah. You can go first if you want. Okay. Yeah, I mean, let's say if I only had to pick one, it's salmon. I mean, that to me is probably going to be number one on my list. After that, probably coconut. I would have that. And this is for myself. I could eat those things a lot. I would probably pick some type of fruit or carbohydrate. I would think it would be probably blueberries. Yeah. And then I might do, I would either do olives or avocado. And then I might do like a sweet potato, something like that. Now, the only other thing I am thinking of is that maybe I would want another source of protein.

1:41:18And so maybe, you know, I'm trying to think of iron levels right now. I might have a little bit of a challenge with what I just shared. So I'd probably swap one of those things out and add in like a grass-fed burger. But that's what I would go with. Okay. Nice. Yeah, I would do a grass-fed burger for sure. It's like, okay, so we're saying five. Grass-fed burger. I would say salmon. It's funny. I'm not trying to cheat off of you. That's all right. Great minds think alike. Yeah. I would say salmon. Maybe avocado. Did he say avocado? Yeah. Did he say avocado? Yeah, I said avocado or olives. Okay, I would say avocado.

1:41:53Yeah. I would say berries for, and then I would say pizza, like a good sourdough. Because look, if I'm like, you know what? I like that better. I did sweet potato. That's so much better. If I could have mint chip ice cream every day forever, man, I would do it. Is that your ice cream of choice? Oh, it is. it is it is man i i swear to you i've always been since i was little but it's got to be i i am like a connoisseur of mint chip ice cream and it's baskin robin still to this day is my favorite yeah but interesting yeah i need to check it out i don't know why that's my mother-in-law's favorite it's the best i'm a i'm have to be in the mood oh really i i'm a peanut butter guy so i would do like vanilla with peanut butter that's hard to be we're gonna go into our like after i do round off my five i want to get into our like if we could just cheat with five what they would be our favorite so you know what's funny is most of my list is stuff that i hated until like two years ago i wouldn't touch aside from my number one because if i had to eat something and survive on it every day it would be eggs like oh that's a great one yeah i would never never get sick of it and nutrient wise like i knew i'd be healthy yeah you know yeah so that's my number one but then we start getting into these other ones that i'm like i wouldn't touch an avocado i can't live without it i travel with them because you know if you go to the store and try to buy them in town they're not really ripe it's hard so my wife has them ready for me prepared i will not leave the house without them i will not go a day without those so those would be two for me i eat a lot of vegetables like a lot so i would probably like i'm a zucchini mushroom and peppers guy so if i don't know if i could combine all three or not if that would be okay um but it's your rules it's my yeah i'm just gonna say my veggies right my veggie plate would be three i love salmon which is another thing i wouldn't touch i just get scared about eating it every day unless i know it's like how perfectly caught it is and everything and like with the mercury side of things but if i could eat it every day which i used to till i had a high mercury result i would because it's the best now i like king king salmon or sockeye myself um but that would be it and then it was certainly the if i can't do salmon it would have to be berries um blueberries are my favorites and blackberries and i do that in greek yogurt every day and then the beef you have to do grass-fed beef i think you could easily have that every single day yeah um so let's get into the guilty pleasures the cheat foods if you pick three okay uh well yeah because five's kind of a lot so give me your three what they would be i'm probably just a classic like cast iron chocolate chip cookie i mean i make my own that are probably healthy you know healthier version but i would do something like that i'd probably top that off with vanilla ice cream and then and then just some just dark just straight dark chocolate yeah okay with some salt on it yeah mine probably would be pizza which i put on my top which shows you how good i am i put it in my survival list but i would look this is the truth is that there are better for you versions for all of these things like i'm not going to go to dominoes no fence dominoes i'm just not gonna do that i but you don't need to like you can get an amazing good quality organic sourdough pizza gluten-free if you include free anyways i would do sourdough pizza i would do peanut butter which i would put on that list because it's not really nutrient dense uh but it tastes so good i agree and then third man do you remember this i'm gonna put this on the list because i haven't i forget the name it was like called nutter butter or nutty buddy it was like a peanut shaped wafer cookie thing yeah of course yeah uh i haven't had it since the 90s so i need to like find it but i would that would be on my list or you know what i was in the gas station i was driving my son down here he goes to college down here and it was the white powdered donuts oh man i'm like man i haven't had this since 1997 and i thought what if i bought that i didn't buy it but i did well if i knew that it wouldn't hurt my health and like i would be okay to have this i would get a cheese pizza with extra grease my friend because i just how good it is if i knew like okay i'm going into this where it's not going to hurt me so it would be the mint chip ice cream the pizza for sure i like just i either get plain cheese pizza or i've always been a green pepper and mushroom guy you know like like or roasted peppers whatever so those two things for sure and then it's like okay because you need the peanut butter is yeah and i like walnut butter i don't know if you guys ever had that no i've never had it but but i consider that more of a health yeah like side than a cheat side so i would say i'm italian i grew up like around it all the time so like just continuous pasta every day would be my other one i i don't even touch it anymore my mom always says do you want me to make it i'm like no i don't i But inside, yes, I do.

1:46:44But no, I don't. So those would be mine. OK, so I want to bring this up. We go in extremes, like we said. Now, right now, it's the protein extreme. Every single thing has to be protein. And I've always been a guy coming from the bodybuilding world where if I got a guy I'm training hard that needs to gain size, we'll do the 1.5 grams of protein to pound of body weight. I don't love to get on this. Oh, you got to have per pound of body weight. but what are you guys' feelings on how extreme it's getting? What's too much? What's too little? Cause I've seen some crazy people. Okay. Crazy thoughts about eating too little.

1:47:22I don't want to say crazy people, sorry, but like really low, which I find to be detrimental long-term, but I think too high is also detrimental. So what are your thoughts? And then also what are your thoughts on the ability to actually process like 70 grams of protein in a meal? Is that getting turned into sugar? Like some people say, or what, give me some facts on this. Yeah. I think, look, I think from a public health standpoint, I actually think it's great what the HHS did recently with highlighting it and increasing it slightly. The requirements, because yes, we're not talking about malnourishment, but are we thriving?

1:47:56And I think most Americans aren't getting enough high quality, but it's the American way. Maybe it's the human way. We like to overcorrect. So it's like, I am annoyed at myself right now to have talk about protein right now, because this is people are inundated on social media all the time. And it's just, look, trends will come and go. It's having its sort of zeitgeist moment, protein is. But the truth remains the same. Whether the world's paying attention or not, we need to focus on high-quality protein, but not overcorrect and become obsessive with it. The truth, as I said earlier, the truth is oftentimes somewhere in the middle.

1:48:28And with protein being around that 100 grams a day, depending on your weight, obviously it's going to fluctuate depending on your activity level, age, and health goals. And the quality of the protein matters. but we don't always want mTOR to be high all the time from a longevity standpoint if you look at all the longevity research there's going to be periods of time where you don't want that mechanistic target of rapamycin that which is stimulated by protein to be high all the time i agree from a cellular health standpoint so yeah i think that probably times of less like you i think you said earlier in the conversation where it's like yeah maybe this meal is going to be less or this day is going to be less.

1:49:07There's flexibility there. Or a time of protein sparing or times of fasting. You don't always want to be fasting. It's called starvation. So it's like, I think that to become maniacally obsessed with then getting the protein pop tarts and the protein cold foam and the protein cereal, it's probably not needed. Actually, it's not needed because that's not the goal of this. It's a marketing tool right now. And actually, you weren't there, but I was at Expo West. Were you there? No, I wasn't. In March. And I heard from a lot of the food companies that there's a protein shortage because all of these companies - There is whey protein.

1:49:45There's shortage now. The price has gone up like the oil price right now. I mean, it's like the same thing. Yeah. Yeah. Because of this. Yeah. It's really largely like a marketing tool at this point. They do this all the time. And I remember 20 years ago, they started putting omega-3s in everything. There was omega-3 eggs. Then there was a probiotic craze about 10 years ago. they start putting probiotics and everything then collagen now protein i mean fiber of course has been on and off for years and so it's yeah i mean it's it's it's big time yeah you know i actually designed my own protein there's a website i don't work with them or nothing it's called true nutrition and i go in and because i'm not a big fan of like all whey protein so mine i make the percentages so it's it's beef protein isolates about 55 i do egg white protein i do a little bit of bovine collagen a little bit of mct powder and i make it that way and i found the way that like my body responds to it because i put it in coffee every day and i don't drink protein shakes but i utilize it in yogurt and everything and i've noticed a different body response and digestion and everything through different yeah formulations of it because i i find that to be a good source of of added protein throughout the day but don't become reliant upon it either was my was my point to saying that i see a lot of people do that and you can't compensate for for real food sources of protein so let me ask you guys this then fiber is another one so i've run into some people that think you don't need fiber i disagree with that thoroughly but i a lot of carnivore people especially say you don't need it at all what are you what are you guys's thoughts on that because i'm firmly against that i believe we do that we do need it but you know i'm curious go ahead going to go well yeah i mean my thought is this is i think it saying you don't need it i think it me i think part of it comes down to what challenges what pathogens what things are you going to come up against in the future because i definitely think that there's listen there there are quite a few studies that show your diversity is important you know i think for the most of this conversation is probably around people that are on carnivore diet most of the people i know they get on carnivore, they do it because they're sick and they have an immune issue where their immune system's overreacting.

1:51:56And not even overreacting, it's just reacting because it's in this sort of, typically it's autoimmune or mold or some sort of thing where your immune system is on high alert constantly. And I do think if you're decreasing your total microbial, your total microbials, you're going to have less histamine, your body's going to have less reaction, less systemic inflammation. and so that's why they do it. But I do think that not having bowel movements and I do think, or having very few, because if you're in carnivore, you're not gonna have very many bowel movements. I do think it's a problem. I mean, I had a PhD on the show, James D.

1:52:35Nicolantonio. Yeah, yeah. And he brought this up and I thought this, he said, you know, I have some research that says that if you stay in carnivore, your body is gonna move into being too acidic. Now, I'm not talking about this. I remember this drove me crazy 25 years ago, the whole pH thing. Alkalinity. But they can't. I mean, we're talking about the one person. So you can move over into being too acidic, and your body will start pulling minerals out of the bone that are more alkaline, like magnesium and calcium and other things to start to try and keep your pH in balance. That was his perspective.

1:53:05He said he had some evidence and research on that. I think that could be true. Listen, I don't think that for most people, being carnivore is a great diet long-term. And maybe your question was also there about fiber. If you're not getting fiber, again, the studies show that that's not ideal for most people. I mean, people that do more fiber tend to have better insulin levels, tend to have better microbial diversity. Those are, I guess those are my thoughts. Yeah, I think that, yeah, I agree with you. You have to meet your gut. I got a big patient base that I've seen over the past 16 years of people with autoimmune and gut health issues.

1:53:44So I think sometimes that context is lost. You have to meet your gut where it's at. So yeah, you're telling someone that has a wrecked gut, an inflammatory autoimmune issue, maybe you can't have all the 30 grams of fiber that you're hearing that you need. So you may be low fiber for a while while you heal your gut and build low, slow titrate over time as you build resilience. And look, fiber is not the only way to build microbiome diversity, though. I mean, you may have polyphenols, like really focus on the olive oil that we talked about earlier or the berries, which has some fiber. But I think that you want to actually bring more polyphenol-rich foods in, which may or may not have some fiber, but the polyphenols themselves build and promote bacterial diversity.

1:54:30But I agree. But you know what? It's so interesting. Who are the people that are saying this now? Because there's staunch, staunchest carnivore people I knew six, seven years ago. They eat more fruit than vegans do now. So there's, I think people, again, that make it their personality to say like this, everybody, and this applies to everybody. They don't, like we see people as far as patience for all day long. So if I hung my hat on one way for everybody, I'd be proven wrong all day long. so you have to have an intellectual flexibility to bio individuality because it's like bro you are just talking about yourself yeah at the season of your life don't apply that to everybody that's exactly what happens what happens is and some of it's good it's good intentions it's it helped them yeah so they feel like that's where they come they feel like oh i did paleo or i did vegan or i did and it helped me that means everybody should do this thing to help me but to your point with like like paul saladino and he's a really smart guy and and it helped him with some of his issues.

1:55:30I know a lot of people with mold, it helped them. But now to your point, a lot of them now are they add in fruit and then honey and then eggs and then they add in fruit, you know, vegetables. I mean, so they kind of keep going because really you're typically, if you're healthy, you're going to be trying to get a lot of those foods in your diet. That's just it. Things go in phases and stages, right? And so I'm always trying to be careful when I say, well, you should do this because I am. I like to break down, this is where I had problems this is what i did to fix it now here's where i'm at today and this is what's working right now but the the therein goes that term flexibility because we change as we age body response change microbiome changes exactly conditions change and some of the foods or exposures we have to things change that's right you know and and you have to you have to be able to pivot and accommodate and be ready to do that and stress levels change too like is it the food or is it your mental state and spiritual state when you eat the food that's it that vagal tone that we talked about earlier.

1:56:27Yeah. So if you guys could leave everybody with one thing today of importance that you really want to stress right now, and I know there's a lot that we would all like to wrap around here, but what's one thing each of you would like to leave with people from what we discussed today and what you really feel of value? Yeah, well, I'll just say that I think it's important to know that God designed you uniquely. There's no one else in the world like you. And so you need to be eating foods that are right for you, supplements that are right for you. I mean, have something that's tailored that's ideal for you to follow for you to reach your optimal level of health.

1:57:03And that's one thing we try to do in Heal Yourselves is we really lay out how to reverse the irreversible, how to heal anything. We go through protocol. People can take a quiz in there and find out which organ might be aging faster, what protocol they need to follow. And we have a protocol in there that people can follow. But I think that, you know, that personalized medicine is the future and that's where people see the biggest results. Yeah. I would say your body is amazingly resilient, but you have to do something different to see something different. You know, a big percentage, my intention for this book as it comes out into the world is that the people that are medically gaslit, people that are told they're crazy, there's nothing wrong with you, that they know intuitively something's off, not to become a hypochondriac and look for problems where there aren't problems, but you know your body.

1:57:50And we really wrote this book for those people, those people that have what the world may call mystery illnesses or the people that just know they're not feeling their best. They know this isn't just age or just stress or whatever it is, they know something's off here. And the science is pointing to this, but there's such a gap between what's in the scientific literature and then it trickling down to conversations that people are having with their doctor. It may never happen because it's a training within the paradigm and they're trained to diagnose a disease and match it with the pharmaceutical drug.

1:58:23So we are having conversations that probably they've never had before ever with their doctor. We got to have in the book. So I'm excited for people to read it. I love it. I would just like to say, set yourself a foundation. I'm a God first foundational person. And I believe that that will set the stage for your healing and your growth as a person and who you can become for yourself and then for everybody else around you. And I just want to say this, too. When you become more selfless and not selfish and you take care of yourself, then you're taking care of your loved ones around you. You can be your best you and you prioritize people and your your resilience as a person and who you are meant to be.

1:59:07That's living. That's what it's all about. It's not about you. It's about what you do for the people around you. And that makes you the healthiest and the happiest and the best you can be for everybody around you. So I just want to say this, what an honor and joy and pleasure it is to sit here with you guys. I mean, it really is to me. I was sitting last night and I was going, wow, I can't believe that I'm going to get to sit with two people like so esteemed and so amazing and brilliant. And I get to just be a part of that and be here with you guys. It means a lot to me. I know God brought us together here for messaging, but what you guys do, not just this book, which is amazing, all of these years of sacrifice that you've given and the way that you've conveyed message that you've been abused, you've taken shots from people and you're just, it makes you go harder.

1:59:55I love that about you guys. And to be able to sit here and do this and share it with you, like, this is why I live. And so I just beyond the thank you for that, it's just gratitude to be here with you and to share this. And I really hope everybody listening just really takes into what you guys do and teach because it's amazing. Thanks, man. Thanks so much. Appreciate it. So you're saying you're saying not everybody likes us. I think that the three of us are not for everybody, but I think we are for a lot. So that's going to wrap it up today, everybody. Thank you so much for joining us. I hope this hits home and just remember, prioritize your health first, live that long and healthy life.

2:00:37Cellular health, God first, and we love you.

From the publisher

Your hormones, your sleep, your stress, your diet — they may all be affecting your health at a much deeper level than you realize. Dr. Josh Axe sits down with functional medicine expert Dr. Will Cole and fitness and biohacking educator Dylan Gemelli for a no-holds-barred roundtable on what may actually be driving chronic disease, accelerated aging, hormonal dysfunction, and poor metabolic health — and why healing may need to start at the cellular level.

In this episode, we learn why Dr. Axe and Dr. Cole believe cellular health could change how we approach chronic disease — and how to identify which systems in your body may be aging faster than others

Uncover what’s really going on in your body with advanced biomarker testing for hormones, thyroid, and metabolism — plus a 1-hour consultation with a Senior Health Advisor! → http://mybloodwork.com

Disclaimer: The bloodwork our team runs at mybloodwork.com covers a handful of the biomarkers listed in the guide above — including critical thyroid and metabolic markers — plus a 1-hour consultation with a Senior Health Advisor, but does NOT cover all 25. You will want to consult your primary or functional doctor for the entire list.

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Discover practical steps you can take today to start healing your thyroid naturally → http://DrAxeThyroidClass.com

If you’re ready to start feeling like yourself again and balance your hormones, take my free class → http://DrAxeHormoneClass.com

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CONNECT WITH DR. WILL COLE
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CONNECT WITH DYLAN GEMELLI
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Podcast → The Dylan Gemelli Podcast

TIMESTAMPS:
00:00 — The Biggest Drivers of Chronic Disease
02:29 — Welcome to the Health & Longevity Roundtable
03:07 — Why Cellular Health May Be the Future of Medicine
06:10 — Is One of Your Organs Aging Faster Than the Rest?
08:22 — How Early Do Health Problems Really Begin?
12:30 — The Blood Markers That Could Reveal Heart Disease Risk
18:12 — What Insulin Resistance Actually Means
19:59 — The 2 Hormones That Can Throw Everything Off
22:58 — The Surprising Connection Between Sleep & Insulin Resistance
25:10 — “I’ll Sleep When I’m Dead” Is Destroying Your Health
31:32 — Waking Up at 3 A.M.? Cortisol May Be the Reason
32:43 — How to Lower Stress & Support Your Vagus Nerve
37:18 — How Your Mind & Nervous System Affect Your Health
41:32 — Can Childhood Trauma Keep You From Healing?
43:55 — Forgiveness, Faith & the Nervous System
48:11 — Why Dylan Believes Health Starts With “Mind, Body & God”
51:11 — Can Faith Actually Help You Live Longer?
58:35 — The Truth About Peptides & Where Medicine Is Headed
1:03:29 — Are Peptides Overhyped or the Future of Health?
1:05:31 — Conventional vs. Functional Medicine
1:10:14 — How to Increase Your Healthspan, Not Just Your Lifespan
1:11:01 — Why Gut Health Matters for Longevity
1:12:46 — The Best Exercise for Mitochondria & Healthy Aging
1:16:23 — Why Women Shouldn't Be Afraid of Strength Training
1:19:32 — Keto, Carnivore & Vegan: Why Extreme Diets Can Backfire
1:21:29 — Bio-Individuality: There Is No Perfect Diet for Everyone
1:27:30 — Is Health Advice Actually Making People More Stressed?
1:29:03 — Seed Oils vs. Saturated Fat: What's Actually Healthier?
1:39:12 — The 5 Foods Josh Axe & Will Cole Would Choose for Life
1:43:11 — Josh & Will Reveal Their Favorite Cheat Foods
1:45:29 — Are We Eating Too Much Protein?
1:50:01 — Do You Really Need Fiber?
1:55:12 — The #1 Health Lesson From Josh, Will & Dylan
1:57:16 — Dylan's Final Message: God First, Health Second
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