How Peptides and Bioregulators Heal the Brain, Liver, and Heart

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1:17So you'll know how to take the quality of your sleep from okay to very high. Know your sleep score with Apple Watch. iPhone 11 or later required. Believe it or not, your organs can literally get younger, not with surgery or organ transplant, but actually reversing your organs age. And this was discovered some 40 years ago. And there's a whole science behind it using peptide therapy or a specific type of peptides called bioregulators that might actually be able to turn back the clock and make your brain younger, your heart younger, your skin younger, your hormones younger. I mean, can you imagine as a man having double and triple the levels of testosterone?

1:58Or as a woman, you are able to fly through menopause, having more balanced levels of progesterone and estrogen and thyroid hormones without taking hormone replacement therapy, drugs, and other sorts of conventional medicine. Well, today I'm going to be talking about these advanced form of peptides called bioregulators, which are just now creeping into the United States, which I believe are the future of healing. Welcome to the Dr. Josh Axe Show.

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3:58Oftentimes these sort of topics around this exact podcast get shadow banned. So if you want to make sure you get cutting edge episodes like this in the future, make sure you're subscribed. I know many of you are subscribed, but many of you aren't. So if you want to keep up with what's going on, the most advanced scientific breakthroughs in the world today, whether they're fully legalized or not, make sure to subscribe here to the show. It helps you keep seeing the truth rather than being silenced. All right, let's dive in here. What are bioregulators? Well, bioregulators are very small, naturally occurring protein snippets or types of peptides.

4:35They're technically ultra short chains of amino acids, also known as short peptides that are between two and four peptides in length. And they act as genetic switches turning on and off genes. Now, of course, we know this is important. If you're familiar with breast cancer genes or even things like MTHFR, we have these genes in our body that can be turned on or off. And peptides tend to turn the wrong genes off and turn the right genes on if you have them in sufficient amounts. And recent medical evidence has shown that they may help restore heart function, brain health, liver function, your immune system, and so much more.

5:18In fact, the leading researchers of bioregulators, Dr. Cavinson, along with other scientists, have demonstrated that these peptides can extend the lifespan of mice by up to 40 % in some studies. Now, the origin of bioregulators came with this Dr. Cavinson, and his research began as a secret project for the Soviet Union's military and government, which wanted to reverse premature aging caused by radiation exposure. And after decades of research, Cavinson developed a range of peptide-based pharmaceuticals and dietary supplements that have been introduced into clinical practice. So this is something that has started to grow in areas like Russia and Asia, and now it's making its way into the United States.

6:06And as you age, your organs don't just get slower. They can become dysfunctional and your brain loses speed. Your immune system starts to weaken. Your digestion can become off and your heart becomes less efficient. But you can actually turn back the biological clock by supplying your organs with these peptides, also known as bioregulators. And many of these peptides and bioregulators have started to be used by everything from the cosmonauts to Olympic athletes and professional athletes. But now it's making its way into anti-aging and functional medicine. And I myself have started using these with patients for improving sleep, hormone imbalances, supporting testosterone levels, supporting patients with hypothyroidism, helping people overcome chronic pain issues, chronic fatigue syndrome, a number of benefits we see around peptide therapy.

7:03And these specific peptides called bioregulators. And you can get some peptides and bioregulators in the injection form or even in capsules. And of course, also straight from real foods, especially organ meats, which I'll get into, is where you'll find many of these as well. Now, I do also want to mention why this happens to be a gray area with peptide therapy, because pharmaceutical companies are wanting to get their hands on things so they can make these things for pennies and charge you a lot of money. And unfortunately, that's the reality.

7:33Josh Axe:I mean, the crazy part is these bioregulators are found naturally occurring in organs and glands. But what we're able to do is take those compounds and do them in higher doses to where if somebody has, for instance, a weakened immune system, we can do these thymus gland peptides in higher doses, And it does tremendous things for boosting the immune system. Well, of course, pharmaceutical companies are spending all of this money on lawyers trying to create patents around certain peptides. So you have to pay a large amount of money for them. The other thing it does is they actually will have to go through some regulation.

8:10Josh Axe:So if the pharmaceutical companies have their way, you wouldn't even have access to these peptides for another 10 plus years. And that's why it's such a gray area right now. And certain peptides aren't fully legalized. Even though a lot of people, you can go to many functional medicine or cellular medicine clinics and you can get peptide therapy today, it is not fully legalized. legalized. Only reason being is pharmaceutical companies are trying to patent these drugs. Here's an example. Certain types of peptide therapy we know are more popular than ever, like semiglutide GLP-1, like Ozempic and Monjaro.

8:48And of course, those are mainstream. Why? Because pharmaceutical companies have their hands on them and are now making billions of dollars off of these types of peptides. But the reality is, again, these are more like supplements than they are medications. Again, they're peptides. I obviously started a company many years ago where we were the number one or two selling brand of collagen, collagen peptides, right?

9:14Josh Axe:Collagen's a peptide. Where's that coming from? It's coming from the ligaments and the tendons, not necessarily an organ per se. It really actually could be considered a type of organ if you consider your muscles and your connective tissue organs. but you're getting loads of peptides from that, right? So we consume peptides anytime you're drinking bone broth, anytime you're taking a collagen peptide supplement, you are getting peptides. And those are type of peptides that are very good for your ligaments, joints, and your connective tissue. But there are other peptides that are great for your thyroid hormones, that are great for your immune system, that are great for your brain.

9:51And what peptides tend to do is they help improve communication within your body. Now, I am grateful we have Robert F. Kennedy Jr. in office because he is aware of this, and he is fighting and trying to legalize peptides fully. And here is actually one of his only quotes where he is referencing peptides, and here's what he says on a post on X. He says, The FDA's war on public health is about to end. This includes its aggressive suppression of psychedelics. peptides, stem cells, raw milk, hyperbaric therapies, chelated compounds, ivermectic, hydroxychloroquine, vitamins, clean foods, sunshine, exercise, nutraceuticals, and anything else that advances human health and can't be patented by pharma or pharmaceutical companies.

10:42Josh Axe:This is an exact quote by Robert F. Kennedy Jr. And what RFK Jr. is talking about is obviously not conspiracy theory. This is just pharmaceutical companies are saying, hey, we see this being the next billion dollar industry. We want our hands on it and we want to control who gets it and be able to mark it up to make a lot of money. We see Robert F. Kennedy Jr. as we talked about, he's been referencing peptide therapy and bioregulators. We see Joe Rogan. He had a nagging elbow issue with tendinitis and he said it vanished within two weeks of using BPC-157. So we see Robert F. Kennedy Jr. using these.

11:19We see Joe Rogan using these. I've got numerous

11:21Josh Axe:friends like Ben Greenfield and Will Cole and many others that are using them themselves. Neuroscientist Andrew Huberman claimed two injections resolved his L5 spinal pain, a condition that normally takes months to heal. We've seen numerous athletes using this. One in particular had a major hamstring tear and recovered much, much faster than he should have because of using peptide therapy. So bioregulators and peptides, they don't replace hormones or directly provide your body with nutrients. Instead, they travel to specific organs, bind to the DNA in the nucleus and turn on repair and regeneration genes.

12:05Okay. So for

12:06Josh Axe:instance, you know, I myself experienced this when I had a life-threatening infection. I was bedridden for a year, couldn't walk and had so much inflammation, pain and tissue damage because the infection around my L5 vertebra, in fact, the infection went from my disc into my full bone. The entire bone was infected and an abscess around my spinal cord. And I had a lot of damage there. And I had a doctor tell me that I may be permanently disabled, I would likely be permanently disabled, I could die and I would have chronic pain every day because the damage would be so bad and they would likely have to fuse my spine because the degeneration.

12:42Josh Axe:Well, I got turned on to two things, stem cell therapy and peptide therapy. And I started doing a fairly high dosage of BPC-157, TB-500, and GHKCU. This is a peptide blend. I was doing it subcutaneously daily. And after six weeks of doing it, I was blown away at my pain reduction. And the thing that was so amazing was it's not like I had pain, it went away, and then it came back. No, I had pain, it went away, and just kept getting better. I mean, that's what was so amazing in terms of just the improvement I saw in a short period of time. And the reason that worked was these different types of peptides went into different organs in my body.

13:24They started turning things on saying, we've got to take our healing and regeneration up a notch. And as you get older, your body isn't as good. It loses some of its capabilities of repairing and regenerating. And the amazing thing is, is our bodies are continually healing and regenerating.

13:42Josh Axe:I mean, every seven years, almost 100 % of your body is new. It's at least a 70%. Sometimes it's much higher. But for many of you, when you're regenerating is you're not regenerating very well in creating fully new, healthy, younger tissues. What peptides do is they improve the communication process and they turn on these genes so you can fully heal. And you might notice this, right? If you're in your 40s, 50s, 60s, you're like, man, when I was 18 years old, I would have an injury. And a week later, I was back playing sports and I felt fine. And I didn't have this long-term damage from it. Well, today you have something happen.

14:18Josh Axe:It takes two weeks, four weeks. It's constant. Your tendinitis, whatever it is. And what peptides do is they actually can help you fully regenerate and heal some of those tissues and help optimize their function. Now, they do many other things outside of just tissue regeneration. And I'm going to touch on a few of those things right now. But there are over 20 identified bioregulators. And each organ has its own, by the way. So the thymus gland has bioregulators. Your thyroid, your testes, your ovaries, they have bioregulators. And they've been shown to restore circadian rhythms. In fact, one in particular, Epitalin, is great at this.

14:57Reverse aging of certain immune organs. Improve brain function and memory. Regenerate the liver and kidney tissues. normalize blood pressure and cholesterol, lengthen telomeres, strengthen mitochondrial function, and so much more. Think of peptide bioregulators as your body's original software. They're coded to reboot cellular function at the level of your DNA, helping you rebuild your body and promote healing. Now, again, I've referenced both of these things, peptides and then the shorter chain bioregulators. Peptides tend to be longer chains of amino acids that often act like hormones. They are signaling molecules that bind to receptors

15:40Josh Axe:and trigger specific effects like BPC-157 for the gut and in tissue repair. That's actually, there's proof of this out of the International Journal of Molecular Science. So several medical journals have already proven the benefits of BPC-157 for tissue regeneration. Another peptide, CJC-1295 or ipamoralins, another one. These have been shown to help increase more human growth hormone. And then there's thymus and alpha-1. That comes from the thymus gland. That's been shown to boost immunity and tamp down autoimmune reactions and reduce inflammation. Again, what bioregulators are, they're much shorter, usually two to four amino acids long.

16:20By the way, you might be familiar with shorter peptides like creatine.

16:26Josh Axe:Did you know that's a tripeptide? It's actually three amino acids connected together. So creatine is a type of peptide. It's a tripeptide, so it's glutathione. And so these are things we know scientifically that have major, major benefits. I mean, think about all the benefits of creatine and glutathione. Those are those shorter, three-stranded amino acids that are very similar to bioregulators. They turn genes on or off. They don't act like drugs. They restore normal function. By the way, here's what drugs do. They force your body to do something oftentimes it doesn't want to do. I'm going to force your blood pressure down.

17:06Josh Axe:I'm going to force your cholesterol down, right? That's what drugs do. What bioregulators do and peptides and vitamins and minerals is they give your body what it needs in order to function at the highest level possible. They might increase communication. It might give you a building block. It may optimize the detoxification pathway. That's what peptides and vitamins and minerals do. Drugs force your body to do something. And so bioregulators, what they do in essence is restore normal function. Now, standard peptides work through cell surface receptors, whereas bioregulators cross the gut barrier, penetrate the blood brain barrier and enter the cell nuclei directly.

17:51So that's the big difference.

17:52Josh Axe:So you're not going to have peptides because they're longer. They're not going to go through the blood-brain barrier and the gut barrier often cases. What bioregulators will do because they're so small is they will pass through and they actually enter into the cell in a lot of cases. The key difference is this. Peptides stimulate, bioregulators normalize. Are you interested in functional nutrition tips to burn fat, reduce inflammation, improve your brain and energy levels, and heal naturally? then I want to encourage you to listen to my friend, Dr. Dave Jockers' podcast, The Functional Nutrition Podcast.

18:26This podcast is designed to help you with easy, actual steps to improve your nutrition and lifestyle, understand your lab work, and address the root cause factors that may be driving up inflammation in your body. Now, I've been friends with Dr. David Jockers for 20 years, and he's truly a world expert in functional nutrition, cellular healing, and so much more. If you want to learn the best nutrition and natural healing tips, Tune into the Dr. Jockers Functional Nutrition Podcast on Apple iTunes, Spotify, YouTube, and wherever you can listen to podcasts worldwide. Peptides, or specifically bioregulators, follow an ancient Chinese medicine principle,

19:06Josh Axe:and it's called this, like heals like. Organs and glands, when you consume them, help heal other organs and glands. Now, we also know this extends into Chinese medicine with certain foods. For instance, like supports like. When you look at a beet, you cut it open, it looks like it's bleeding. That has nitric oxide that supports the blood, right? Carrots look like your eyes. Celery looks like your bones. Reishi mushrooms look like your adrenal glands and kidneys. And so they support those organs. Walnut looks like a hemisphere of your brain. It supports the brain. Well, this is the principle bioregulators function in is it's like supports like.

19:43If you take a bioregulator for the thyroid, it is going to improve your thyroid function. If you're taking a bioregulator for your liver, it's going to support your liver function.

19:56Josh Axe:That is what happens because what bioregulators are, when Dr. Cavinson was doing research, he said, okay, well, what are the peptides found in thymus gland or in the thyroid? Okay, I'm going to discover and look at those thyroid peptides. I'm going to study those peptides in the thyroid and create thyroid peptides that can be now taken as a supplement. And so I want to say this. If you want to get bioregulators and peptides in their most natural state, consume a lot more organs and glands. Like one of the supplements I take regularly is not just liver, which I do a lot of liver, but I do organ and gland supplements a lot.

20:34Josh Axe:I mean, that is your greatest natural source of bioregulators. as part of a natural cancer therapy or immunotherapy. When people had weakened immune systems, they would take thymus gland and also sometimes multiple other glands that support your immune system, like the spleen and other glandulars. When they were going to detox, of course, we know the original Gershon therapy had you juice a lot of vegetables and actually juice calf liver or eat raw beef liver. Okay, and so, but why? because he was trying to support the liver and detoxification channels and like supports like. So he had them eat a lot of liver, but there are specific peptides and bioregulators in those organs and glands that you can benefit from.

21:19But for many of you, you need a higher dosage than what you're gonna get in a food to experience the greatest level of healing. And so you're just gonna get a more concentrated dose, which is really what all supplements are, right? Here's an example.

21:32Josh Axe:When you eat an orange, an orange might have 60 milligrams of vitamin C. Okay. If you're taking a thousand milligram dose, right? That's of course, that's like eating, you know, probably, you know, close to 15 oranges. That's a lot of oranges, right? To get up to that dosage. So my point is, is it works like a supplement in that way. It's just a higher dosage and you're going to notice, experience more of a difference. But on a day-to-day basis, I'm doing organs and glandulars. And then if I need some sort of a natural form of medicine, that's where I'm taking key bioregulators. And here are some of the most studied and promising organ-specific peptides and bioregulators you need to know about.

22:11First one here is called thymulin, okay? This comes from thymus gland. This regulates the immune system, slows aging, and reduces your risk of infections. It's used in cancer support and viral illnesses and recovery. And as I mentioned earlier,