The Generalist cover art
Podcast · 50 episodes

The Generalist, page 2

by Mario Gabriele · English

“The future is already here. It’s just not evenly distributed.” The Generalist Podcast brings you weekly conversations with the people who live in these pockets of the future – visionary founders, prescient investors, and original thinkers. Each episode is designed to introduce you to new ideas, technologies, and markets and help you prepare for the world of tomorrow.

All episodes, page 2

Why Psychedelics Might Be the Breakthrough That PTSD Patients Need (Kevin Ryan, The Godfather of NYC Tech)"The future is already here. It’s just not evenly distributed."28 Oct 2025 · 1 h 8 min
The Trillion-Dollar AI Hardware Opportunity (Navin Chaddha, Managing Partner at Mayfield)In this episode, Navin Chaddha, a seasoned venture capitalist with over three decades of experience, discusses the burgeoning trillion-dollar AI hardware opportunity, the evolution of AI technology,…21 Oct 2025 · 1 h
Biological Time Travel: How Cryopreservation Could Transform Medicine (Laura Deming, CEO & co-founder of Until)Biological Time Travel: How Cryopreservation Could Transform Medicine14 Oct 2025 · 1 h 6 min
"This feels like 1996": Why a16z's Martin Casado believes the AI boom still has years to run (General Partner)In this episode, host Mario Gabriele interviews Martin Casado, a General Partner at Andreessen Horowitz (a16z), focusing on the ongoing AI boom and its implications.7 Oct 2025 · 1 h 25 min
How to be Agentic in the Age of AI (Cate Hall, CEO of Astera)Agency in the context of AI development and how individuals can cultivate a sense of agency in an increasingly automated world.30 Sep 2025 · 1 h 11 min
Can Humans Stay Smart in the Age of AI? (David Krakauer, President of the Santa Fe Institute)In this episode of *The Generalist* podcast, host Mario interviews David Krakauer, President of the Santa Fe Institute (SFI) and an expert in complex systems.23 Sep 2025 · 1 h 21 min
Building Beautiful Homes with Robots: The Future of Construction (Salar al Khafaji, CEO & Founder of Monumental)In this episode of *The Generalist* podcast, host Mario discusses the future of construction and the role of robotics in this industry with Salar al Khafaji, CEO and Founder of Monumental.16 Sep 2025 · 1 h 20 min
What Makes Something Alive? Assembly Theory and the Origins of Life (Sara Walker, Theoretical Physicist)Sara Walker, Theoretical Physicist9 Sep 2025 · 1 h 17 min
Reviving Forgotten Technologies: How Airships, Supersonic Flight, and Geothermal Energy Could Transform Our World (Eli Dourado, Head of Strategic Investments at Astera Institute)Eli Dourado, Head of Strategic Investments at Astera Institute19 Aug 2025 · 1 h 11 min
Inside General Catalyst’s $1B+ Bet on Fixing Healthcare (Hemant Taneja, CEO & Managing Partner)In this episode of *The Generalist* podcast, host Mario interviews Hemant Taneja, the CEO and Managing Partner of General Catalyst (GC).12 Aug 2025 · 1 h 16 min
The Future of Crypto: Stablecoins, AI Integration, and the Path to Mass Adoption (Jesse Walden, Founder & Managing Partner at Variant)In this episode, Jesse Walden discusses the current state of the cryptocurrency market, the evolution of stablecoins, the implications of new regulatory frameworks, and the intersection of…5 Aug 2025 · 1 h 13 min
AI Agents Are Here: What They Can Already Do—and What’s Next (Stanislas Polu & Harrison Chase)In this episode of The Generalist Podcast, Stanislas Polu, CEO of Dust and former research lead at OpenAI, and Harrison Chase, CEO of LangChain, discuss the evolution of AI agents from their…29 Jul 2025 · 1 h 18 min
The Decade of Data (Tomasz Tunguz)In this episode of The Generalist Podcast, host Mario Gabriele speaks with Tomasz Tunguz, founder and managing partner of Theory Ventures.22 Jul 2025 · 1 h 4 min
Why the Real Computer Revolution Never Happened (Alan Kay & Anjan Katta)In this episode of The Generalist Podcast, host Mario Gabriele explores the future of computing in the context of artificial intelligence (AI) with two distinguished guests: Alan Kay, a pioneer of…15 Jul 2025 · 1 h 29 min
No RivalsThis episode features Part I of a four-part series titled "No Rivals," focusing on the Founders Fund, a prominent and controversial venture capital firm in Silicon Valley, founded by Peter Thiel.8 Jul 2025 · 49 min
Existential Risk and the Future of Humanity: Lessons from AI, Pandemics, and Nuclear Threats (Toby Ord, Author of "The Precipice")Weekly conversations with visionary founders, prescient investors, and original thinkers about new ideas, technologies, and markets shaping the future.24 Jun 2025 · 1 h 19 min
Are We Alone In The Universe? Sara Seager on Exoplanets, Venus, and the Hunt for Alien Life (Astrophysicist and Planetary Scientist at MIT)The Generalist Podcast engages in weekly conversations with visionary founders, insightful investors, and original thinkers who are at the forefront of emerging ideas, technologies, and markets.17 Jun 2025 · 1 h 7 min
Antimemetics: Why Some Ideas Resist Spreading (Nadia Asparouhova, Writer & Researcher)In this episode, Nadia Asparouhova, author of *Antimemetics: Why Some Ideas Resist Spreading*, explores the phenomenon of "antimemes," ideas that actively resist being remembered or shared.10 Jun 2025 · 1 h 19 min
Creating Stars in a Bottle: The Race to Commercialize Fusion Energy (Vinod Khosla & Bob Mumgaard)In this episode, Mario Gabriele speaks with Bob Mumgaard and Vinod Khosla about the revolutionary potential of fusion energy.3 Jun 2025 · 55 min
The Semiconductor Century with Chris Miller (Author of “Chip War”)Chris Miller, Author of *Chip War*27 May 2025 · 1 h 4 min
How Anduril Is Reimagining the Defense Industry: Faster Tech, Ethical AI, and a New Kind of Deterrence (Trae Stephens, Co-Founder & Executive Chairman of Anduril)How Anduril Is Reimagining the Defense Industry: Faster Tech, Ethical AI, and a New Kind of Deterrence20 May 2025 · 1 h 27 min
Inside Substack’s $650M Playbook for the Future of Media (Chris Best & Hamish McKenzie, Co-Founders)In this episode of *The Generalist*, host Mario discusses Substack's innovative approach to media with co-founders Chris Best and Hamish McKenzie.6 May 2025 · 1 h 26 min
Lessons from 20 Years of Venture Capital (Roelof Botha, Managing Partner & Steward at Sequoia Capital)In this episode of *The Generalist*, host Mario speaks with Roelof Botha, Managing Partner at Sequoia Capital, about his two-decade journey in venture capital and the principles that have guided…29 Apr 2025 · 1 h 21 min
When Science Fiction Becomes Reality (Josh Wolfe, Co-Founder of Lux Capital)When Science Fiction Becomes Reality15 Apr 2025 · 1 h 27 min