Stocks Drop In Major Reversal… And Opportunities In A Red-Hot Biotech Sector 11/20/25

20 Nov 2025 · 44 min

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Podcast Episode Notes: CNBC's "Fast Money" - Stocks Drop In Major Reversal… And Opportunities In A Red-Hot Biotech Sector (11/20/25)

Overview In this episode of "Fast Money," hosted by Leslie Picker, the focus is on a significant market reversal driven by a sell-off in stocks, particularly after Nvidia's disappointing performance and a delayed jobs report. The episode also discusses the buoyant biotech sector, which is outpacing the broader market due to increased merger and acquisition (M&A) activity.

Key Topics Discussed

  1. Market Reversal and Nvidia's Impact
  2. Initial Rally: Stocks opened higher, buoyed by Nvidia's strong earnings.
  3. Sharp Sell-off: The Nasdaq fell over 2%, with the Dow seeing a swing of more than 1,100 points.
  4. Bitcoin Crash: Bitcoin continued its decline, hitting lows not seen since April.
  1. Interpreting Market Behavior
  2. Volatility Index (VIX): Rose above 28, signaling increased market fear.
  3. Sell-off Dynamics: The discussion centered around the nature of selling versus buying—panic selling often leads to sharper declines unlike reluctant buying.
  4. Technical Analysis: If the S&P closed below 6,500, it could indicate a significant reversal month, highlighting the market's volatility.
  1. Walmart's Resilience
  2. Earnings Report: Walmart's stock rose over 6% following strong earnings and raised guidance amidst consumer concerns.
  3. Inflation Indicators: Minimal inflation reported at Walmart, suggesting better consumer health.
  4. Leadership Changes: Transition in leadership at Walmart and Target discussed, with insights on their competitive standing.
  1. Biotech Sector Opportunities
  2. M&A Activity: The biotech sector is revitalized with 18 billion-dollar deals recorded, indicating strong investor interest and potential for growth.
  3. Investment Trends: Transformative therapeutics are driving valuations and interest in the sector.
  4. State Investment: Texas leading in biotech funding with initiatives aimed at bolstering research and development.
  1. Jobs Report Analysis
  2. September Jobs Report: 119,000 jobs added, but unemployment rose to its highest since October 2021.
  3. Federal Reserve Outlook: The jobs report’s implications on Fed interest rate decisions discussed, with a general consensus that rates may not be cut soon.
  1. Tech Stock Performance
  2. Consumer Tech Stocks: Companies like Netflix, Spotify, DoorDash, and Uber faced significant drops, raising concerns about consumer spending.
  3. Valuation Concerns: Many stocks previously thought to be solid are now being questioned due to high valuations amidst declining trends.
  1. Final Thoughts and Predictions
  2. Market Sentiment: Mixed views on consumer health and potential market recovery.
  3. Panic vs. Orderly Declines: The nature of the current sell-off debated, with some traders arguing it’s more systematic rather than panic-driven.
  4. Future Market Moves: Expectation of continued volatility, with cautious optimism in the biotech sector.

Key Takeaways

  • The market is experiencing significant volatility, exacerbated by mixed signals from major tech stocks and an uncertain economic outlook.
  • Walmart's robust performance offers a contrasting beacon of strength amidst broader consumer fears.
  • The biotech sector is a focal point for investment opportunities, fueled by M&A activities and innovative therapeutics.
  • The jobs report indicates a labor market that is stabilizing but not without its challenges, affecting Federal Reserve strategies.

Conclusion Leslie Picker's hosting of this episode highlights critical market movements and the varying sectors' responses. Traders and investors are advised to navigate this turbulent market with caution while keeping an eye on sectors like biotech that show promise.

For more information, visit [Fast Money on CNBC](http://fastmoney.cnbc.com).

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Transcript

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0:02Live from the Nasdaq market site in the heart of New York City's Times Square. This is fast money. Here's what's on tap tonight. NVIDIA in reverse, the semi-giant giving up gains of more than 5 % and ending the day down 3%, what the roller coaster ride means for the rest of the market. And winning Walmart, the retailer beating estimates for the latest quarter and upping expectations for the year, how the big box company is navigating a questionable consumer landscape. Plus, digging in on the long-delayed September jobs report, a weak signal for internet stocks and more gains in biotech. We talk with 1BC about whether the healthy returns can continue for the sector.

0:44I'm Leslie Picker in for Melissa Lee, coming to you live from Studio B at the NASDAQ. On deck tonight, Carter Worth, Dan Nathan, Guy Adami, and Mike Coe. Thank you all for being here. But we begin with the massive reversal on Wall Street. Euphoria over NVIDIA's Blockbuster earnings last night fading fast. The hyperscaler up more than 5 % at the open, but ending the day sharply lower. That whipsaw action took the major indexes down with it. The Nasdaq giving up nearly 3 % gain today to end the session down more than 2%. The Dow swung more than 1 ,100 points from high to low in the S &P end of the day, more than 3 % off its highs.

1:22All closed near their lows of the session. Bitcoin also failing to get off the mat, continuing its plunge toward the key$85 ,000 level. It set a new low dating back to April. All of this action pushing the VIX above 28 at its highs. Wall Street's so-called fear gauge closed its highest since April. So what does today's action tell us about what to expect through year end? Guy, first of all, maybe just take a step back. What the heck happened? Well, let's take a step back from that. Yeah. And say this has been a historic week here on Fast Money. Jim Cramer came on Monday night, first time ever.

1:59More importantly, you're hosting this show, Leslie Picker, and we are thrilled to have you. Thank you. Your coverage in the financials has been fantastic, so it's great to have you tonight. I will now answer your question. What the heck happened? Well, you know, we've been talking about the volatility index on this show for a while. The fact that on a couple different occasions over the last month, you've seen spikes to the upside, and we thought those were sort of a precursor or maybe sort of rumblings on what is yet to come. What else was going on? You mentioned Bitcoin. When the Nasdaq was up at its highs today, Bitcoin was not moving.

2:29As a matter of fact, it was going lower. To me, that was sort of a sign that, you know, maybe this rally is going to be somewhat short-lived. I don't want to pretend that I knew this reversal was coming, but here we are. What does it mean? Well, you don't see reversals like this all that often, and I think they're very powerful. And Carter can speak to this. If you get a close below 6 ,500 this month of November, which is now in its 20th day, we're going to start talking about outside reversal month, which rarely, if ever, happens, Les. Well, that's right. I mean, so to put it in context, obviously, there's always the thought that there has to be some news item.

3:01Was it NVIDIA? Is it the fear maybe in crypto? Often things just start to sell off and there's something called, hey, get me out. When people are buying, they buy reluctantly. They say, oh, well, I missed my price. I'll stop. But when they sell, they want to say, and they do, get me out, which is to say they sell without regard for price. So this has a bit of a panic to it. And the question is, is it likely to be contained? And we can talk about this later, but we're now down 5 % plus. That's the first time that's happened since the plunge low of April, the tariff low. You get typically 5 % plus or minus dips, corrections every two to three months.

3:38We've gone seven, almost eight without one. And so this is long overdue, and I wouldn't think it stops here. So this is a pretty voracious turnaround, though. This is especially lacking some sort of a catalyst. So do you think there is some sort of technical, you know, maybe it's momentum reversal, maybe it's short covering last night that then kind of reversed itself today? I mean, how do you look at the internals? At this level, it's maybe a bit new. But think about this. In the beginning of the month, right, the S &P was at an all-time high, essentially. But the constituents internally of the 500 stocks, the average stock was down some 15 % from its own respective 52-week high.

4:11So it's been these great winners that have held the whole thing up. And now we're seeing some trouble in paradise. So presumptively, the index has more to go. Yeah, so Carter just mentioned reluctant buying. And I think that's what you probably saw after the print last night in NVIDIA. You know, we're sitting around. This is 24 hours ago. We're looking at what they reported. Everyone expected a better than expected number. They expected better than expected guidance. You look at that margin number, and I guess our take at the time was that, you know, great, they have an upside in gross margins.

4:37Well, who is that at the expensive? It's expensive all their customers, right? And so my reaction is like, okay, let's look at the hyperscalers. Let's look at the biggest sort of buyers of those sorts of chips, and let's see how they act today. And they were starting to give it up really quickly. And then I was looking at some of the component suppliers to the server makers and the servers that go into the data centers. And you saw right out of the gate, memory was weak, storage was weak. You know, those neoclouds were up a lot. They did not have a hard time giving up all those sorts of gains.

5:05So Oracle, one of the biggest customers, that thing got absolutely killed. That was my final trade. I actually thought it would continue to rally in this sort of environment. But this is actually the most vulnerable of the ones. They got all these great contracts, except they don't have the money to pay for the infrastructure build. And I think the market's coming around to that. Even the competitors to NVIDIA, look at AMD and look at how that closed today. That went down fairly quickly on the day and it closed down 8%. But, you know, when you look at NVIDIA, it was the largest market cap company on the planet and the expectations and the focus on it.

5:35And you say to yourself, OK, who is the incremental buyer of this on good news? And I think that's really what happened. And when you have a stock like this open on the day at the high of the day and close on the low of the day, You know, the expectation that this is going to turn right away, especially in the environment that we've been in, is probably not a great one. And so to Carter's point, if you see sort of panic selling, and Guy makes this point all the time, what do they say? They don't talk about it to the upside? Well, it's funny. We don't use the word panic to the upside ever. When you hear panic, it's usually associated with a sell-off.

6:09The reality is most of the panics over the last couple of years, you can argue they've been to the upside because to Carter's point, you know, people feel like they're missing. And I don't think today was panic at all. I think it was somewhat orderly. The VIX is telling a little bit of a different story, but the sell-off to me was sort of run-of-the-mill. Yeah. The internals also, I mean, 150 stocks in the S &P were up. That's not an over—when it's really bad, you get 490 down, right? So can there be follow-through? That's the real question, because tomorrow morning you've got to make decisions, each of us and everyone.

6:38And the presumption is there's more to come to the downside. Yeah, well, it seemed like the decision making that everyone was expecting from last night just totally reversed midday today. Mike, what is your take? Well, you know, it's interesting. We often talk about rallies broadening. And sometimes I kind of look for signs that maybe some weakness is also broadening. If we go back about five weeks or so, there were a lot of high flying, high beta stocks that are probably more speculative in nature. So we're not talking about the invidias of the world. Now we're talking about things like Palantir and hims and hers, those types of names.

7:15And a lot of those began to suffer pretty considerably at about that time. And NVIDIA, Alphabet, these are the types of names that everyone thinks of as the highest quality and so on. And so to me, I think the bloom started to come off the rose when those stocks started to roll over. A little bit of a sign that those who are willing to take the most risk in the market were less willing to do so. And so I'm kind of with Carter on this one that, you know, we often look to the VIX as a potential barometer for when you think things are oversold. But the hazard in doing that is that before you get to higher levels, you must go through elevated levels.

7:52That's where we find ourselves. We move from elevated to high, but it could still go a little bit higher. I think we could see a little bit more of a flush before it's all said and done. Yeah. To Guy's point, we talk about panic to the downside, momentum to the upside, but they both technically work both ways. And they feel very right. And it's the same mechanism. It's just different words. So people associate down with bad, up with good, which I totally understand. But panic works both ways. Yeah. Meantime, one bright spot in the market is Walmart, ending the day more than 6 % higher after beating the street sales and profit estimates thanks to strong e-commerce growth.

8:27The big box retailer also raising its full year guidance for the second quarter in a row. For more on the quarter, former Walmart U.S. CEO Bill Simon joins us now. He's also on the board of Darden Restaurants and the chairman of Haynes Brands. Thanks for being here, Bill. What's your overall takeaway in terms of the state of the consumer versus some of the strategic initiatives that Walmart has been driving in order to gain share here? Well, there's a lot of good in that report for Walmart and I think for the consumer in general. You know, the first thing that struck me is after really, you know, six or eight months of, you know, us hearing about inflation, tariff driven inflation, there's almost no indication of any inflation in Walmart's report.

9:12I think they reported about 1.2 percent inflation. And that's really, really a good indicator for the rest of the economy because they're so broad in how to do so. So I think fears of inflation and we all sort of were worried what the tariffs were going to do. I think we can put that one aside at least for the for a little while and see how it goes. The second for me is Walmart has such a huge portion of the snap, I think about 25 percent or almost twenty five billion dollars a year in snap. And to see my worry was that they were going to struggle as the snap benefits got turned off during the shutdown.

9:49We didn't see that. You know, if they'd have seen it in November, they wouldn't have raised their guidance. So those are two really good indicators that the consumer's in pretty good shape for me. Yeah, and you've got some change at the top of both Target and Walmart. What do you think that means about their competitive posture at this point in time? And how do you kind of assess the changes that are taking place at each of those retailers? Well, you know, Brian Cornell and Doug both went into the role roughly around the same time. They were peers at Walmart with me at one point, so they know each other really well.

10:26And they're both transitioning out at the same time, and they're both being replaced by insiders. I think in the case of Walmart, that's probably a good thing, maintaining the momentum that they have. In Target's case, it's going to be a challenge because they need to make some changes going forward. Anytime there's big structural changes like the CEO changes and board chair changes, there's a risk in the transition. And I think that's something that they're going to have to both deal with. I think Walmart's in a better position to deal with that than Target is. But we'll see. We'll agree to disagree on the consumer, Bill.

11:00But thanks, obviously, for joining us. You don't need to look any further than today's action. Walmart are basically at an all-time high target at a 52-week low on a day where the market didn't perform very well. People have tried to shoot against Walmart on valuation for a long time unsuccessfully. Does valuation matter at this point or just operating better than everyone else? Well, I think they're operating better than everybody else. You know, valuation is really something that I think Walmart's been concerned about for years. You know, they were built as a brick-and-mortar retail, CapEx heavy, asset heavy, and they're valued that way.

11:35Now, they're valued at the top end of a retailer, but that's sort of at the bottom end of a digital company like Amazon. And I think this move to NASDAQ is their effort to try to get more of a digital valuation into the company than a brick and mortar valuation. So they're concerned about valuation. Otherwise, I'm not sure why they'd be doing what they did. Hey, Bill, help us think about Costco. And when you think about their business and you think about just the stock performance over the last few months or so, it's really underperformed that of Walmart. Walmart, as we just said, is trading very near those all time highs.

12:08But even before that, it's just been basing for a while. Right. And so what is the investor dislike, I guess, about Costco and what's going on there relative to Walmart? Yeah, in the brick and mortar retail world, Costco is honestly as good as it gets. They've they've been able to put up really strong, consistent numbers for years. Their merchants are superior than really anybody else. And they've got a model that allows them to retain their their their key people. I think they're very undervalued. There's some structural issues in the club segment. Sam's is doing OK. They're sort of coattailing on on the Walmart valuations.

12:45But I think I think that there's some structural issues. You know, the family size and the quantity size isn't really lending itself towards towards the big club business as much as it might have been at one point. And I think they don't benefit as much from the growth in Snap at Costco as, say, Walmart does. Huh. Interesting points. Bill, thank you so much for your time today. Appreciate it. You bet. Carter, your take on Walmart? Well, I mean, Dan makes his point. So Walmart, after one of its great advances over two-year period, is sideways for now almost 10 months. So that's what is a breakout candidate.

13:19You go up, you rest, and then in principle, you reassert yourself to the upside. Just now, breaking out. Real quick, Bill sort of, he didn't gloss over it. He mentioned it. That's a big deal, Walmart, coming to the NASDAQ. It's the biggest move ever from one exchange to another exchange. Courtney's coming on. She can speak to this. I think it's their way of saying, you know what, we're a retailer, but we're a technology-focused retailer. That's a big deal for the NASDAQ and for Walmart as well. Yeah, a signal for their digital franchise there. Sticking with retail, you mentioned, Courtney, we have an earnings alert on Gap.

13:50shares there higher in the after hours after the company reported its best same-store sales growth since early 2018. The conference call started at the top of the hour. Courtney Reagan joins us now on set. Shares up 4.3 percent. I know. It's a really good day for retail. The week didn't start out strong, but it's ending that way, at least right now. And I do want to start with those comparable sales because in total, all the Gap brands together up 5 percent. As Leslie said, That is the strongest non-pandemic comp since the quarter ended January 2018. So that was also a holiday quarter. Gap itself up 7%.

14:23That was twice as good as expectations. Old Navy up 6%. Banana Republic up 4%. Athleta, it's the smallest, but we have to mention it because it was down 11%. A lot of work to do there. Now, earnings of 62 cents. That was stronger than 59 cents. Revenue is also stronger than expected. Gap raising its full year net sales outlook to that upper end of the previous range. and then increasing its full-year operating margin guidance. I spoke with Gap CEO Richard Dixon, who's on the call right now, getting ready to take questions from investors, and he said, Gap is exceeding expectations. We are winning with all income cohorts with equal growth in low, middle, and high incomes.

15:01Dixon has seen consistency and strength in our customer behavior. CFO Katrina O 'Connell explained that the tariff impact estimate is unchanged, And while it did have a 190 basis point hit to gross margin, the stronger sales with less discounting offset almost all of it. So it left gross margin down just 30 basis points from last year. And Dixon acknowledges disappointment with Athleta's performance, as I mentioned. But he says that he believes the new president, she's just 90 days in, is taking the right steps. He is confident that the brand will re-emerge. and Gap CEO Richard Dixon will be joining Jim Cramer on Mad Money at 6 p.m.

15:38for an exclusive interview. So we'll get to hear more from him directly when he does get off this call with investors. Well, yeah, it feels like the brand is reemerging. What have they been doing to try and win back that brand equity? Because those numbers, the best in eight years for comparable sales growth, I mean, that's nothing to shy away from. Right. So Gap is doing what I think Target wants to do. They're trying to get back that cool factor. And the CEO always talks about trying to be back in the cultural conversation. I don't know if you've seen any of the ads, but they've had Parker Posey in recent ads, and she had a lot of hit with a lot of success with the White Lotus hit.

16:12They just had this, you know, other campaign that's sort of kicking off the holiday season that has really gotten a lot of people talking. The CEO says that it has sort of reignited the past love, some nostalgia from some of us that might have shopped at the Gap in high school with our restaurant paychecks. I don't know who that was, but, and then also sort of reintroduced the brand to Gen Z. He's really trying to mesh music back with fashion. And it's an easy thing to say. It's a hard thing to do. But two years in, it does look like it's starting to take off. Yeah, the marketing push with Gap, American Eagle.

16:47I don't know if you've looked at Old Navy, but their kids clothes are really cute. And the prices are compelling, but without having to discount so much. And that's how they're pulling in that lower income consumer and really being able to hold on to those margins even after the pressure from Jaros. Yeah, we had to make a pit stop there on the way to your son's birthday party. So we did. Yeah, that's right. That old Navy experience, unexpected, but still worthwhile, still productive. Mike, what's your take? Yeah, I mean, look, Gap Stores was trading at about 10 times next year's full year adjusted EPS estimates.

17:21And that was on very narrow margin expectations, actually narrower than what they had been experienced over the trailing 12 months, even before these results came out. And when you put that together, basically the better the top line and the better margin picture that they just articulated, you know, the move that you're seeing after hours here, I think, could be just the start of something a little bit better. Because, I mean, I don't see any reason why this couldn't trade 14 times. And that's, you know, a meaningful 30 % premium to where the stock's trading right now. Yeah, it definitely feeds into this whole brands from the 90s and early 2000s are just making their way back to the forefront of the cultural consciousness.

17:58Coming up, it wasn't just earnings impacting the markets today. How the long-delayed September jobs report factored in as well and what it means for the Fed's next great decision. One top central bank watcher weighs in. Plus, Netflix, Spotify, DoorDash, and Uber all getting hit hard in today's sell-off. We dig into the charts to see if the carnage will continue. Don't go anywhere. Fast Money is back in June.

18:24Welcome back to Fast Money, the much delayed September jobs report showing better than expected payroll growth for that month. One hundred nineteen thousand jobs being added, though the unemployment rate ticked up, hitting its highest level since October twenty twenty one. But with no jobs data coming for October and November, the November report delayed until after the next Fed meeting. How is the central bank looking at this data? Let's bring in Ben Emmons, founder and chief investment officer at FedWatch Advisors. Ben, it's good to have you. There is such a data vortex right now. How much stock should we put into the September report, the revisions from August and net net what that means for the Fed?

19:08Hi, Leslie. Well, I felt it was a bullish report because, as you mentioned, this unemployment rate rising is really for the good reason. You know, the report showed there was about 475 ,000 people coming back in the labor force. And then there were actually people that were long-term unemployed. There's actually a few of them now long-term unemployed. There's one other sort of tidbit in that report. So I thought it was actually a really good report for the Fed to vindicate their view that this labor market may have had softening. And that's what those revisions from August show. But that is not falling off a cliff.

19:42And that's what this report actually shows. So the market actually responded to this with wake-up probabilities dropping really sharply because, yes, the Fed doesn't have a reason here to cut rates immediately because there's no alarm on the labor market. Yeah, odds now sitting around 40 % chance of a cut in December. Do you think that's the right likelihood? I think so. I mean, we talked about it previously that this Fed seems to be willing to stay on hold simply for the reason that they do feel that this labor market isn't deteriorating, but they're dealing with this inflation picture that's not cooperating the direction that they want to.

20:22You know, Beth Hammack was talking to Steve Leesman earlier today. She's making, again, a pretty strong case there like we're dealing with elevated prices. You know, and it's funny that that's against the Walmart earnings that show that, you know, there's not much pass-through coming to their earnings there. But, you know, overall, the inflation picture isn't really what the Fed wants it to be. So I think this probability will stay low. There's always a chance that you will go forward if anything changes. But I think they're on hold for December and go forward with January potentially. You know, Ben, Carter correctly has pointed out that the bond market is really nowhere over the last year and a half.

20:56We're waking up. It's 4.1 percent. We've been here before. I still think rates are going higher. I'm not suggesting I'm right. But what do you think is going on here in the bond market? I mean, this is probably best case scenario for the market. There's no bond volatility. Yeah, that's right, Guy. I mean, you know, you and I both want to share this view that rates should be significantly higher. This is an economy. It's so much like stimulus coming in over the course of next year with all this investment. You know, you should actually see yields more closer to 5%. But I think what's happening is that there's some, I think, hedging, some diversification against this equity market.

21:33And I picked it up from client conversations that bonds do look a little bit more attractive in that perspective. And secondly, we don't have really any major surprises from the Fed in one way or the other, which kind of keep that volatility lower. And then it's about sort of the situation where who's going to be the next Fed chair? What are they going to do from there? I think does play a role because we saw from the comments from the president the other day, they really want to bring rates down. I think that sits in the market's mind since February to try to jawbone it down. And I think that's why you've seen some buying flows in bonds, even though yields should be higher because of a good economy.

22:10I know you've studied what's going on in private credit quite closely. That was an area of concern for several Fed officials this week as well. We saw the Blue Owl merger get terminated amid concerns there, which is all playing into this broader market sentiment surrounding business development companies that have exposure to private credit, which have sold off. How do you think that all plays out? Leslie, what you saw today with Lisa Cook with a speech out putting a specific section on private credit and then mentioning there that it's drawing their attention because it's grown so fast, so quickly and there's now some stresses building there and this Blue House example is one other example of that that although not falling apart I don't think there's a financial contagion playing out yet but they are getting the attention of the Fed And I think the Fed will go from here with the SEC and the FSOC, which are bodies to start looking at private credit more specifically and saying, you know, what can we do here in order to not let this morph into another subprime example?

23:18So I think that's what's playing out here. And this negative headline coming from that does affect markets because people don't like the opacity of private credit. This idea that money is tied in there, it's illiquid, and we actually don't know what the marks really are. That was an example blew out, too. So this will stay a bit with us. And that's what the Fed's really going to do as we go from here. Sounds like from Lisa Cook's speech that they're paying real attention to. So we should we should really keep an eye on this. All right, Ben, thank you so much. Appreciate your time this evening.

Read the full transcript

23:48Thank you. Carter, what's your take? Yeah. You know, I mean, Guy refers to think about it. We are basically at four percent. Right. And we were at four percent three years ago. So if you look at the autumn of 2022 to right now here, the autumn of 2025, rates have done absolutely nothing. The highest they've been is 5%, the lowest, 3.25%. We're sitting at the midpoint. It is the reason that the so-called Goldilocks narrative has been, okay, we can have any multiple we want because we don't have to worry about a spike in interest rates. I'm in the lower yields camp, so that's on the opposite side of Ben and Guy, but that's what makes a market.

24:18I am a buyer of treasuries. At the same time, there's tighter funding conditions for credit right now. Are you surprised, or do you think there is a risk that we could see more volatility? You're seeing CBS in a name like Oracle, and I know a lot of folks were kind of pooh-poohing it a week ago. You know, you look at this deal that Meta has done with Blue Owl and KKR to get this financing for this Louisiana data center off their balance sheet. I mean, there's a lot of stuff going on, and it's not nearly, I guess, as transparent as some of the other lending that we see. So you might see tighter spreads, right, in some of the stuff that's being quoted in the public markets, but you don't know what's going on, I guess, in the private market, too.

24:56So, you know, there's stuff going on here. And, you know, Oracle was one of the first companies, the first stocks to go down today. It's already sold off about 40 percent from those highs post that OpenAI contract. And it closed down six and a half percent, a huge reversal, 10 percent intraday. So, again, you could say this is just fundamental. There's some technical things at stake and there's some other things that are going on that a lot of folks are not going to be able to put their finger on until we look at it, you know, after the fact, I guess. Yeah, it's just a tremendous amount of debt being issued over the span of two months, essentially.

25:28And the market's just trying to digest it. There's a lot more fast to come. Here is what's coming up next. A few green arrows in today's sea of red. The restaurant stocks bucking the downtrend and whether our traders are biting into them. Plus, biotech buys, M &A action shaking up the health care space this year. Will that lead to bigger gains where our next guest sees the most opportunity? You're watching Fast Money live from the Nasdaq market site in Times Square. We're back right after this.

26:09Welcome back to Fast Money. Some restaurant stocks buckling, bucking today's sell off and giving investors something to bite into. Kate Rogers has the details. Kate. Hey, Les. So a lot of red across the sector, but a few names ending the day. Green. Fast food names, Yum! Brands and McDonald's up around a half a percent today. Restaurant Brands International, Burger King's parent company, also up around a quarter of a percent to end the day. All three of those names also among the only positive sector performers year to date in this really challenging environment for the restaurants. Jack in the Box, which reported earnings today with tough same-store sales comps and an update on its turnaround plan.

26:46The stock actually climbing nearly 8 % to end the day. We should note, though, it is a small market cap name of just under$300 million. Finally, coffee company Dutch Bros climbing about 1.5 % today. The biggest restaurant sector loser on the day, Cava. That stock down over 4%. It's interesting to see that some of the names that would cater to a lower-income consumer did wind up performing better today, particularly those fast food names, as we get more details on consumer sentiment with retail earnings in focus right now. Leslie, back over to you. Kate, thank you. Guy, what is your take about kind of the bifurcation we're seeing?

27:23When growth stops in restaurants, and Kate can talk about it, and it happened in Chipotle, it's happening in Cava now. Nobody looks at valuation on the way up when you have comps growth. And when it stops and turns, the first thing that people look at, and then you're done. And that's what's happening in those names. Flip side of the coin. So McDonald's is sort of the Walmart in the space if you look at it. Slow and steady, making all-time highs, coming off a quarter that wasn't great, but people are saying it 23 times next year's numbers. They can get their arms around something that really seems to have a granular hold on the consumer in a pretty meaningful way.

27:56Yeah, there's a key advantage to being the biggest, to having that scale in this environment. Mike, what's your read? Yeah, I think you could also take a look potentially at Yum! Brands. Yum! Brands also is sort of occupying that same segment. You've got Burger Habit and Pizza Hut and Taco in there. And, you know, this one also trading around 22 times forward. And we're probably looking, my guess is adjusted EPS. I think it's a relative conservative estimate at about 9 % year-on-year growth. And maybe even slightly better top-line growth than you're getting out of a McDonald's. So I think this is another place to look.

28:30Good flag there. Coming up, a booming year for biotech. More than doubling the performance of the S &P. And now even outperforming the MAG-7. Where our next guest sees the most opportunity. And the M &A action heating up the space. Fast Money is back in two. Welcome back to Fast Money. Another check on today's major market reversal. Stocks rallying early in the session, but losing steam quickly as NVIDIA gave up its post-earnings pop. The Dow closing the day down nearly 400 points. The S &P falling 1.5%. And the tech-heavy Nasdaq leading the losses down more than 2%. Bitcoin also dropping hard, falling below$87 ,000, hitting its lowest level since April.

29:16And some more after-hours action into it and Ross Stores, both topping EPS and revenue estimates. And check on shares of Citigroup. CEO Jane Frazier announcing that finance chief Mark Mason will transition out of his role in March of next year, being replaced by Gonzalo Lucchetti. Frazier also announcing a reorganization of Citi's personal banking business, which Gonzalo led, making its consumer cards unit a standalone business. Biotech not immune to the sell-off today, though the sector is still up about 22 percent so far this year as measured by the IBB, the group getting a boost after several years of underperformance, thanks in part to a big pickup in M &A.

30:0118 deals worth a billion dollars or more have been struck so far in 2025 as Big Pharma looks to replenish their pipelines. Early stage startups also benefiting from the deal flow. For more, let's bring in Portal Innovation CEO John Flavin joining us here on set. The venture firm provides funding and lab space to early stage life science companies. It is really wonderful to have you here because this has been such a big move for an area that was really left for dead for the better part of the last few years. Do you attribute it all to kind of the sentiment shift surrounding M &A, IPOs, I guess, to a certain extent, maybe when that window opens back up in 2026?

30:44Well, you touched on a really important topic, you know, the patent cliff that faces big pharma. They need to be replenishing their pipeline. And thankfully, one of the things that I think is driving the valuations in the space is science. There's transformative therapeutics being developed that are creating better outcomes for patients across a range of different therapeutic areas, including neurology, disease of the brain, cancer, autoimmune diseases. I think that's had a profound impact and acquisition has picked up. With acquisitions now at$100 billion for the year, it's over double what was seen last year.

31:18When that happens, you know, the venture investors that put the money in in the beginning reap strong returns. They're able to recycle that money and put it back into the next generation of innovative companies. So the funds flow and the juices are finally back in the system after several bad quarters coming out of that nuclear winter that you just talked about. Yeah, it also drives up potential acquisition targets as people start to figure out who might be next. How does all of this change, maybe net-net for the better, net-net for the worse, given what we've seen with NIH cuts, overhauls at the FDA, other regulatory change in Washington?

31:54Do you see that all being more of a tailwind or headwind for the industry? Well, I think when we entered the year, the industry was very concerned about the administration's changes. And some of those changes still are overhangs on the sector. but there's been some bright spots that have occurred that have provided some assurance to investors that the FDA is open for business. Dr. McCary has ambitious plans to accelerate drug approvals. The stats don't show that yet. It's actually shown more rejections and a slower pace of approvals. However, some bright spots, they did pass the recent plausible mechanisms pathway for rare disease drugs, this is a really important breakthrough for especially rare diseases where there's very few patients that have this particular indication.

32:45The big breakthrough happened using a tool called CRISPR or gene editing a few months ago with baby K.J. Muldoon with physicians at University of Pennsylvania Hospital that cured this fatal disease. And so with the FDA passing that legislation, that'll allow more developers to use gene editing almost like as a new form of surgery to fix some of these rare genetic diseases. I think that will open up new business models and continue to help innovators thrive. John, in terms of your business, you're probably in the sweet spot now. You're starting to see some M &A pick up, but the other side of that coin is harder to find deals at the valuations that you want them at.

33:23Is that somewhat accurate? Yeah. And again, I think what we've also seen here is there's been a cleansing of the public stocks. You know, 2021 was a very frothy year coming off of COVID. A lot of those companies that couldn't survive, you know, again, are kind of out of the system. So I think there's a real quality factor that's out there. And to your point, as M &A happens, as more money is made by venture capital firms, they're looking for quality opportunities. And pharma typically is only getting the game with late stage assets. And so as those assets dry up in terms of just, scarcity, it bids up the value of the company.

34:02So yes, but we're still at a part of the cycle where our thesis has been continuing to be buying in the nuclear winter so that as the sun rises, we get the benefit of the upside. Yeah. One thing that stood out to me that was interesting in the producer's notes from you was this idea that Texas is leading the way in terms of state funding and innovation. Usually when I think of biotech, I think of Boston or San Francisco or New York to some extent, what is Texas doing differently? And do you see this as more of a model for other cities and states? I think it's a model for other cities. I think what you've seen is, you know, for the last 50 years, the primary centers of biotech innovation have really been concentrated in Boston and the Bay Area.

34:47As universities have recruited very innovative faculty, as their business model has changed, so the business model of top research institutions today, it's almost like an innovation arms race. They're all trying to build a Division I innovation program, attracting these faculty that are very good inventors. They're going to other places now. They're not only going to Boston and the Bay Area. As that happens, they're going to places like Texas. Texas has a very friendly state for biotech investment. They have a taxpayer bond-funded program,$6 billion, called the Cancer Prevention Research Institute of Texas that invests directly into companies.

35:24We've had a couple companies that were just announced, got$25 million that's part of our portfolio that are based in our Houston location. And follow on to that, they have now just passed legislation for the dementia prevention and research institute of Texas. Taxpayers allowed and will fund$3 billion to go into neurodegenerative disease research. So states, you know, Rhode Island is doing the same thing. We're partnering with them and Brown and University of Rhode Island. Really cool science that's coming out on both on the RNA side of things, as well as neuro and even infectious disease. And so resources being made available by the state as the FDA and the NIH pull back is where the innovation action is happening.

36:09Yeah, you don't typically associate state funding with biotech, but I guess that's changing these days. Thank you, John. Wide-ranging and interesting discussion there. Coming up, internet issues, Netflix, Spotify, DoorDash, and Uber all getting hit in today's market reversal. Is the pain only temporary or do the charts point to more trouble ahead? Fast Money is back in two.

36:36Welcome back to Fast Money. Big losses today on the consumer end of the tech trade. Netflix, Spotify, DoorDash, and Uber all dropping today. while all are still up solidly for the year. They're down double digits from their 52-week highs. Dan, you mentioned these moves earlier. They tend to get lost in the AI trade conversation, but clearly there's a second derivative play here. Yeah, and it's been building for a while. And I think one of the things that Guy said, he respectfully disagreed with Bill Simon about the consumer. I mean, these are largely consumer-facing companies, right? And they've kind of been rolling over now for the last couple months or so.

37:13And so to me, I know Carter will talk about the technicals. I mean, I would think they'd be acting OK here. Some of the valuations in this space are far better than that in the AI sort of trade. And I also say that these are companies that should be benefiting from some sort of spend as it relates to AI, at least in their businesses. And some of them are ad supported. We know that was a big case for Meta. So to me, I think that you're losing legs of the stool of the tech trade. And the semis, I think, for all intents and purposes, are probably the last leg of that. Yeah. And some of the idiosyncratic big names that are still holding out, like a Google.

37:46But the common circumstance with at least a couple of these, Netflix and Spotify, is that they peaked months ago. Both of those two stocks peaked in June. Remember, the stock market only just now in the past two weeks has put in a high. And so it's a testament to respecting relative strength or poor relative strength. These have been topping and rolling, and each one qualifies sort of officially, if you will, as a bullish to bearish reversal sell. Yeah, I was looking at Spotify. It is 45 times forward earnings. So these aren't cheap by any measure, Guy. No, when things are going well, again, people will sort of say, you know, at valuation, we'll sort of put that on the side until people start to look at valuation on sell-offs.

38:25And all the names you mentioned, even Uber, you could say is a little bit expensive. But Dan, I think hit the nail on the head. These are consumer-facing stocks that are rolling over, and Carter said it, for a while now. That is concerning. And again, to respectfully disagree with Mr. Simon, I don't think the health of the consumer is nearly as robust as he does. Mike, what's your take on this whole thing? Yeah, I mean, Netflix is a name that I've liked for a long time, but the trend is certainly extremely worrisome. The valuation is not particularly worrisome. And I think what the trend is telling us is that the forecast right now for close to 30 % year on year adjusted EPS growth might be a little bit ambitious.

39:02So this is a name I would definitely take a look at, but I certainly wouldn't start adding to it right here. We have a position in it already, but I'm not going to add to it until we start to see this thing level off and actually start breaking above some of these downtrends. All right. Thank you. Coming up, another data center deal, the latest open AI move to fortify the U.S. supply chain, who they're partnering with to help with the hardware. More in two.

39:35Welcome back to Fast Money. we have a news alert on a new partnership between OpenAI and Foxconn. Mackenzie Sigalos has the details. Mack, another day, another AI deal? Indeed, Leslie. OpenAI is deepening its U.S. infrastructure push, this time teaming up with Taiwan's Foxconn to develop and manufacture AI data center hardware in America. Now, this deal gives OpenAI early access to evaluate and potentially purchase the server systems that Foxconn designs. So really, this is about OpenAI trying to speed up the deployment of the$1.4 trillion worth of compute commitments it's made in the last two months.

40:11Foxconn, it will make AI server racks with OpenAI and manufacture key components like power, cooling, networking, and cabling systems at its US factories. Now, they haven't specified which site, but we know that they are already building AI servers in Houston. Even though it's best known for assembling iPhones, Foxconn is now the world's largest maker of AI servers and a key NVIDIA supplier. Now, this deal adds a manufacturing layer to OpenAI's supply chain and helps them localize production. It also comes as part of a big hardware push by OpenAI CEO Sam Altman. He signed that$10 billion deal with Broadcom to make AI chips that would ideally rival the NVIDIA GPUs that currently train and run OpenAI's models.

40:52And you'd have to think that Foxconn would be building the racks to hold those new chips, Leslie. Mac, where did they previously build those components for data centers? Were they in other parts of the U.S.? Were they using someone other than Foxconn? Or was it abroad? So to this point, OpenAI has exclusively been using NVIDIA's GPUs. And so NVIDIA does the server systems themselves, the NVL72. But what we've seen notably in the last few months is this push to potentially have OpenAI diversify away from NVIDIA's models. They signed that deal with AMD and then they signed that deal with Broadcom to build their own chips.

41:29And so that's where a partner like Foxconn would be so crucial because they need a server rack to hold it so they could use specs that would be specific to what they're building out with Broadcom. And I will say this, this also comes after, you know, earnings after the bell yesterday, where in the SEC filing, NVIDIA said there's no assurance that they will enter into definitive agreements with respect to the OpenAI opportunity. They're referring to that$100 billion deal. Right. That's a good flag there, Mac. Thank you so much. Dan? Yeah. I mean, some of the contract manufacturers here, Seleska, J-Bill, they did not trade well today.

42:03And, again, you know, who knows? It's hard to break these things out one way or another. But Foxconn is obviously trying to make big inroads here in the U.S., right? And as Mac just – first of all, she just surrounded that trade, by the way. You know, it's just another one of these stories where OpenAI, you can say, well, this is a totally legitimate deal. I mean, they need folks to build these racks that go into the data centers that power their models or train their models. But, you know, this is assuming that all of that one and a half trillion dollars is all going to get funded. It's going to get spent.

42:30It's going to get built out. Yeah. Going back to your earlier point about accounts receivables. Up next, your final trades.

42:43It's final trade time. Mike. Yeah. Respectable results. Buy right. Gap stores. Harder. SMH, sell short. Guy. You're coming back, Leslie. This was great having you. I haven't scared you off yet. McDonald's, not at all. Not at all. All right. Well, thank you for watching Fast Money. Mad Money starts right now.

43:18on this podcast as a specific inducement to make a particular investment or follow a particular strategy, but only as an expression of an opinion. Such opinions are based upon information the Fast Money participants consider reliable, but neither CNBC nor its affiliates and or subsidiaries warrant its completeness or accuracy, and it should not be relied upon as such. To view the full Fast Money Disclaimer, please visit cnbc.com forward slash Fast Money Disclaimer.

From the publisher

An early rally in stocks gave way to a rough sell-off on Wall Street. How Nvidia’s reversal, and a delayed jobs report gave way to a market meltdown, and how Walmart became a bright spot in the down day. Plus, Biotech more than doubling the performance of the broader market, as M&A action lights up the space. Where our next guest sees the most opportunity in the space, and if the biotech boom can continue into year end.

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