Podcast · 14 episodes
Fortune 500: Titans and Disruptors of Industry
by Fortune Magazine · English
Hosted by Fortune Editor-in-Chief, Alyson Shontell, Titans and Disrupters of Industry goes in depth with the powerful thought-leaders shaping both the world of business and the very way we live.
Latest episodes
Sam Altman: AI Beyond Human Control “Absolutely Possible” | Titans and DisruptorsSam Altman (OpenAI) argues that as AI capabilities rise, safety work (monitorability, alignment, and “safety cases”) must progress in lockstep; he rejects training or deployment when teams can’t…12 Sep 2026 · 46 min
Why GM's CEO Mary Barra is Still Bullish on Electric VehiclesMary Barra, GM CEO, explains why she remains bullish on electric vehicles despite slower U.S.9 Sep 2026 · 44 min
Bill Ackman's takes on Mamdani, Trump and investing in the AI eraBill Ackman discusses how he built Pershing Square’s success, his market outlook (especially AI), his approach to investing in “durable growth” companies at discounted prices, and his views on…5 Aug 2026 · 1 h 1 min
All episodes
Sam Altman: AI Beyond Human Control “Absolutely Possible” | Titans and DisruptorsSam Altman (OpenAI) argues that as AI capabilities rise, safety work (monitorability, alignment, and “safety cases”) must progress in lockstep; he rejects training or deployment when teams can’t…12 Sep 2026 · 46 min · 23 chapters
Why GM's CEO Mary Barra is Still Bullish on Electric VehiclesMary Barra, GM CEO, explains why she remains bullish on electric vehicles despite slower U.S.9 Sep 2026 · 44 min · 20 chapters
Bill Ackman's takes on Mamdani, Trump and investing in the AI eraBill Ackman discusses how he built Pershing Square’s success, his market outlook (especially AI), his approach to investing in “durable growth” companies at discounted prices, and his views on…5 Aug 2026 · 1 h 1 min · 27 chapters
FedEx CEO: AI Could Help Fix A $1.8 Trillion Global Supply Chain ProblemFedEx CEO Raj Subramaniam discusses “re-globalization” and how AI, robotics, and network redesign can reduce disruption and inefficiency in global supply chains (citing $1.8T in inefficiency).15 Jul 2026 · 47 min · 17 chapters
$4 Trillion Savings Gap: TIAA’s CEO on The Retirement CrisisThe U.S. retirement crisis and TIAA CEO Thasunda Brown Duckett’s push to make “income the outcome” through lifetime income, plus how TIAA is using AI to reduce fraud and prepare for job/skills change.17 Jun 2026 · 56 min · 17 chapters
AI Takeover: Qualcomm’s Big Bet on AI Agents, Robots and 6G | Titans and DisruptorsQualcomm CEO Cristiano Amon argues AI “agents” will drive a new computing era, shifting the primary interface from smartphones to always-on “personal AI devices” (especially smart glasses), enabled…6 May 2026 · 49 min · 21 chapters
The $8+ Billion Partnership: How Delta and Amex Redefined the Business of Flying | Titans and DisruptorsDelta’s turnaround from early-2000s bankruptcy to premium, profitable growth, and how CEO Ed Bastian leads with a people-first culture while navigating AI, Amex partnerships, sustainability, and…1 Apr 2026 · 44 min · 22 chapters
The end of work: Vinod Khosla's bold AI prediction | Titans and DisruptorsVinod Khosla's bold AI prediction4 Mar 2026 · 37 min · 16 chapters
Google’s AI boss made OpenAI issue code red. Now he wants to solve disease. | Titans and DisruptorsAlyson Shontell, Editor-in-Chief of Fortune11 Feb 2026 · 29 min · 16 chapters
Pfizer CEO took on COVID. Now he wants to cure cancer | Titans and DisruptorsIn this episode of *Fortune 500: Titans and Disruptors*, hosted by Alyson Shontell, Dr.27 Jan 2026 · 49 min · 22 chapters
Kamala Harris says the ‘Glass Cliff’ Suggests Finality: “I’m Not Into That”Kamala Harris reflects on her 107-day 2024 presidential campaign, losing the election, and what Democrats must do next—especially around “glass cliff” leadership, rebuilding trust, combating…15 Oct 2025 · 34 min · 13 chapters
Jamie Dimon on What Kills Companies and the Key to Business LeadershipJPMorgan Chase CEO Jamie Dimon discusses what kills companies, how to lead through uncertainty, and gives an economic and geopolitical outlook (deficits, inflation, tariffs, recession odds).15 Oct 2025 · 46 min · 23 chapters
How Ramp's Eric Glyman Built a $22.5 Billion Startup in 2,367 DaysRamp CEO Eric Glyman explains why Ramp’s corporate spending platform grew to a $22.5B valuation, how it flips incentives to help companies spend less, and how AI automates expense reporting and…18 Sep 2025 · 29 min · 14 chapters
Julie Sweet’s Path From Lawyer to Leading 770,000 PeopleJulie Sweet, CEO of Accenture, discusses leading a 770,000-person company through AI disruption, geopolitical and economic shifts, and major organizational rewiring to become a “reinvention partner,”…28 Aug 2025 · 59 min · 22 chapters