Longevity Doctor: Alzheimer’s Is Preventable If You Do These 5 Things Early | Dr Darshan Shah

22 Jan 2026 · 4 min · 4 chapters

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In short

Podcast Summary: Live Well Be Well with Sarah Ann Macklin

Episode Title

Longevity Doctor: Alzheimer’s Is Preventable If You Do These 5 Things Early | Dr. Darshan Shah

Overview In this episode, health expert Sarah Ann Macklin interviews Dr. Darshan Shah, discussing critical strategies to prevent Alzheimer's disease. The conversation emphasizes the importance of early intervention, understanding the causes of Alzheimer's, and actionable steps individuals can take to reduce their risk.

Key Concepts

Alzheimer's Disease

  • Rising Concern: Dr. Shah acknowledges that Alzheimer's is an increasing concern, particularly for families with a history of the disease.
  • Different Drivers: The episode highlights the notion that Alzheimer's can result from various underlying causes, necessitating a personalized approach to prevention.

Five Key Prevention Strategies

  1. Testing and Early Detection:
  2. Continuous Glucose Monitors: To monitor blood sugar levels.
  3. Inflammation Testing: Using hs-CRP tests to identify inflammation levels.
  4. Urine Toxin Tests: To assess toxic exposure.
  1. Improving Metabolic Health:
  2. Focus on maintaining a healthy metabolism as a foundational step in preventing Alzheimer's.
  1. Reducing Inflammation:
  2. Incorporate habits that lower inflammation, which is a significant contributor to cognitive decline.
  1. Minimizing Toxic Exposure:
  2. Use air purifiers, filtered water, and non-toxic skin products.
  3. Emphasize organic food consumption while avoiding ultra-processed foods.
  1. Cognitive Health Practices:
  2. Engage in Meditation: Helps to exercise the brain and promote relaxation.
  3. Allow time for brain rest to facilitate detoxification during sleep.

Daily Habits to Incorporate

  • Sleep Priority: Emphasize the importance of quality sleep for brain health.
  • Technology Management: Reduce phone usage in idle moments (e.g., waiting in lines).
  • Toxin Awareness: Be mindful of everyday products that may contribute to toxic exposure.

Important Takeaways

  • Timing is Critical: Recognizing potential risks early can significantly enhance prevention strategies.
  • Lifestyle Changes Matter: Simple daily adjustments can create substantial differences in overall health and cognitive function.
  • Holistic Approach: A multidimensional strategy that targets metabolism, inflammation, and toxins is essential for effective prevention.

Additional Resources

  • Full Episode: [Watch here](https://youtu.be/qHFymGgsYyE)
  • Newsletter: [Subscribe](https://sarahmacklin.substack.com/)
  • Website: [Visit](https://sarahannmacklin.com)

Closing Thoughts Dr. Shah emphasizes that even genetic predispositions can be managed through lifestyle choices, making it crucial to implement preventive measures as early as possible. The episode encourages listeners to take actionable steps toward a healthier future.

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*For more insightful discussions on health, lifestyle, and nutrition, tune in to the Live Well Be Well podcast and follow Sarah Ann Macklin on her social media platforms.*

Written by AI. May contain mistakes. Listen to the episode to check what was said.

Chapters

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Understanding Alzheimer's Disease

0:45 to 1:35

Discussion on the impact of Alzheimer's and the importance of preventative measures.

“Yeah, my favorite researcher in this, I love Chris Palmer too, by the way, but also Dale Bredesen is excellent.”

Types of Alzheimer's and Testing

1:35 to 2:25

Exploring different types of Alzheimer's and the significance of testing for prevention.

“And so some of the reasons people get Alzheimer's are poor metabolic health, high levels of inflammation, high levels of toxic exposure, all of those things we can test for, right?”

Key Factors for Prevention

2:25 to 3:25

Highlighting metabolic health, inflammation, and toxic exposure as critical prevention factors.

“That's what's leading to a lot of buildup of toxins in our brain, right?”

Lifestyle Changes for Brain Health

3:25 to 4:23

Suggestions for lifestyle changes, including meditation, sleep, and reducing toxins.

“So making sure you get really, really good sleep and you prioritize sleep is super important.”
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Transcript

Automatic transcript. May contain errors.

0:00Dr. Darshan Shah:Welcome to Live Well, Be Well, a show to help high performers improve their health and well-being.

0:10Dr. Darshan Shah:So Alzheimer's is a big thing. I know you have like a five-stage approach to Alzheimer's. This is probably the thing that I'm the most nervous of. One, because it's in my family. So I've seen it firsthand. I've seen how it can cause just a lot of pain to not just yourself, but also the people around you. it's one of those diseases that really affects the family but it's massively on the rise I've had so many different conversations on this show with Dr. Chris Palmer where he talks about as a metabolic kind of problem and you know we see a rise in obesity and we see a rise in mental health I've had the brain doctors on here who talk a lot about you know Alzheimer's and what we should be doing it is on everyone's minds I think you know the fact that we could all get this at some point what are your kind of main things that we should be doing to avoid Alzheimer's or to try and reduce it and look at prevention.

1:00Yeah, my favorite researcher in this, I love Chris Palmer too, by the way, but also Dale Bredesen is excellent. Have you interviewed him yet? I'll make the introduction. You should have him on for sure. His message is basically like there's different types of Alzheimer's due to different things. And you have to find out what type of Alzheimer's you have and you can do that through testing. And once you know, then you start working on those things and you will decrease your chance of getting Alzheimer's. The critical piece of this puzzle is timing, to know as soon as possible, okay? And so some of the reasons people get Alzheimer's are poor metabolic health, high levels of inflammation, high levels of toxic exposure, all of those things we can test for, right?

1:48We talked about the continuous glucose monitor. We can do a urine toxin test for toxins and see what toxins are building up. who can check for inflammation with the HSCRP and go looking for where you have inflammation. And so even if you have a genetic susceptibility to Alzheimer's disease, you can prevent it by removing all of these problems, right? The other things that you can do to prevent Alzheimer's is to exercise your brain and keep it healthy. How do you do that? Meditation is really, really good. You want to give your brain time to rest. In this life, we rarely give our brains time to rest, especially with our cell phones, we feel like we have to keep our brains constantly active all the time.

2:29And that's a big problem. That's what's leading to a lot of buildup of toxins in our brain, right?

2:34Dr. Darshan Shah:Yeah. I always say the best way someone can do that, that's how I say to myself, when you're in a queue, don't get out your phone. Right. The automatic thing when you're in a queue, what do you do? Get your phone out. Right. Or you're in a waiting room, I better get my phone out. And that's the moment. Because I think it can be really hard to go home and just be like, I'm not going to look at my phone. But actually, we have so many moments in the day when we might go and get a coffee when you're going to the bathroom. Yeah. Massive. Just don't take the phone into the bathroom with you. Exactly.

3:06Exactly. Why?

3:07Dr. Darshan Shah:They're the big moments. Yeah, there's not a time to go look at the phone. Exactly. No one did that until like 20 years ago, right? This is the thing. Yeah. So I think that is a real problem. And so, you know, giving your brain time to relax and just kind of empty is really important. When does your brain clean itself? It's at night when you sleep. So making sure you get really, really good sleep and you prioritize sleep is super important. And then lastly, what I would say too is, you know, I keep talking about toxins, is like really, really reducing your toxic burden in your life. That could come in many forms, like, you know, air purifiers at home, opening your windows at home, not drinking out of plastic water bottles all the time, filtering your water, either with a reverse osmosis unit or through filtration devices, making sure the products you put on your skin aren't toxic products, right?

3:56And then eating organic food and staying away from ultra-processed food, all of that will reduce the level of toxic exposure to your body and let your body catch up and kind of mitigate for the toxins you do get exposed to. So that's very important.

4:11Dr. Darshan Shah:Thanks so much for listening. To hear the full episode, there's a link in the description.

4:21Thank you.

From the publisher

Watch the FULL podcast here: https://youtu.be/qHFymGgsYyE


Worried about Alzheimer’s and what you can do now? You’ll hear practical, testable steps to lower risk by targeting metabolism, inflammation and toxins, plus daily habits for brain rest and sleep. This clip explores the idea that Alzheimer’s can have different drivers, the importance of early testing (continuous glucose monitors, hs-CRP, urine toxin tests), and simple changes like meditation, less phone time, better sleep, air purifiers, filtered water, non-toxic skin products, and eating organic while avoiding ultra-processed foods.


Dr Darshan Shah in conversation with Sarah Ann


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