Bryan Johnson: "Healthiest Man on Earth", Founder of Braintree & The Blueprint Protocol – Longevity, Superintelligence, Radical Health, & Redefining Human Potential

19 Aug 2025 · 57 min

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The Gstaad Guy Podcast - Episode Summary

Episode Title

Bryan Johnson: "Healthiest Man on Earth", Founder of Braintree & The Blueprint Protocol – Longevity, Superintelligence, Radical Health, & Redefining Human Potential

Episode Overview

This episode features Bryan Johnson, a tech entrepreneur and pioneer in human optimization. The discussion revolves around Johnson's Blueprint, a protocol aimed at reversing aging and promoting biological youth, and the broader implications of health, longevity, and technological advancements in redefining what it means to be human.

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Key Themes and Discussions

  1. Introduction to Bryan Johnson
  2. Host: The Gstaad Guy welcomes Bryan Johnson, highlighting his status as the "healthiest man in the world."
  3. Emphasis on Johnson's achievements in health optimization and technology.
  1. Transition from Founder to Health Advocate
  2. Johnson reflects on his past as the founder of Braintree, discussing the sacrifices made for success, such as poor sleep and nutrition.
  3. He discusses a pivotal moment of reevaluating life priorities after selling his company.
  1. Importance of Health and Longevity
  2. Johnson emphasizes the significance of sleep, nutrition, and cellular regeneration in health.
  3. Discussion on the cultural shift towards valuing health over indulgence.
  1. Psychology of Health Decisions
  2. Exploration of societal perceptions about sleep and health, framing sleep as a non-negotiable rather than a variable.
  3. Johnson argues for prioritizing health in decision-making, challenging common misconceptions.
  1. Cultural Trends in Health
  2. Discussion on the rising trend of health as a status symbol.
  3. The impact of technology on health measurement and awareness, making it harder to hide poor health.
  1. The Role of Superintelligence
  2. Johnson expresses optimism about superintelligence solving major health issues.
  3. He warns against complacency; reliance on technology must be accompanied by proactive health measures.
  1. Measurement and Accountability in Health
  2. The significance of tracking health metrics and biomarkers for informed decision-making.
  3. Johnson advocates a portfolio approach to health, combining diet, exercise, and technology.
  1. Social Dynamics and Health
  2. Johnson discusses peer pressure in health behaviors, encouraging a community supportive of healthy choices.
  3. The challenge of societal norms and the pressure to conform to unhealthy behaviors.
  1. Vision for the Future
  2. Johnson aspires for a collective movement towards valuing life and health, drawing parallels to the global response to crises like COVID-19.
  3. His vision includes fostering a culture that prioritizes life, health, and personal responsibility in decision-making.
  1. Final Thoughts
  2. A La Poubelle (To the Trash): Johnson suggests discarding the mindset that prioritizes the mind over the body, advocating for a body-led approach to health.
  3. Fantastique (Fantastic): Celebrating the extraordinary potential of current times, Johnson encourages a child-like enthusiasm for the advancements and opportunities ahead.

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Key Takeaways

  • Health is Cool: The perception of health is shifting from indulgence to prioritization, showing that being health-conscious is becoming a status symbol.
  • Technology as a Tool: Emphasizing the importance of measuring health metrics to make informed decisions about one's own health.
  • Community Support: The need for a supportive community to encourage healthy choices and counteract peer pressure.
  • Cultural Mindset Shift: Advocating for a paradigm shift that sees the body as a wise steward of health rather than the mind.

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Conclusion

The episode presents Bryan Johnson's unique perspective on health, combining personal experience with broader societal observations. His commitment to redefining human potential through health optimization and the integration of technology offers an inspiring blueprint for listeners seeking to enhance their own well-being and longevity.

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Transcript

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0:03When did making plans get this complicated? It's time to streamline with WhatsApp, the secure messaging app that brings the whole group together. Use polls to settle dinner plans. Send event invites and pin messages so no one forgets mom's 60th. And never miss a meme or milestone. All protected with end-to-end encryption. It's time for WhatsApp. Message privately with everyone. Learn more at whatsapp.com. Hi, Brian. Hey. Thank you so much for having me and having us in your home today. This is surreal after having watched you do a couple of interviews with interview words that I admire and a couple of my friends, Mike and Logan, whose podcast I actually broke character on for the first time.

0:47I felt like you were doing the same with them as well. You were like showing a different side of yourself and just hanging out with the guys. It was very cool to see. Yeah, yeah. Logan became a friend a couple years ago and I guess like a year ago. And so we've been messing around with stuff. So yeah, we had a lot of familiarity going into the conversation. He's in this complicated situation because his profession, he's basically getting traumatic brain injuries. You know, he's being body slammed. Yes. And he's also trying to be very healthy. So I was telling him like, hey man, be careful. I saw he's done like 50 MRIs, but you've done similar.

1:21Yeah. Yeah. So he definitely is probably doing the best job out of all the wrestlers in terms of proactively taking care of his health and monitoring the health effects. But I don't know. I'd like to see if wrestlers have a similar kind of profile as professional football players, you know, successive concussions. And like when they – I went to a WME event recently, and they get after it. So I don't know what the whole body damage is, but it's pretty significant. For Logan's sake, I hope he's okay. Yeah. Around the world with your host, the Stardguy, We welcome you back to the Stad Guy podcast, sharing stories of excellence with those in the know for those who just know.

2:09Again, thank you so much for having us in your home. I know that this is around the end of your day typically. So this would be the equivalent of having an interview on my side at 10 or 11 p.m. Yeah, that's right. So I really appreciate you welcoming us into your home today. I assume the audience knows you very well, but for those who don't know, welcome to the Shtad Guy podcast. Brian Johnson is the man trying to live the best and longest on earth. You are the healthiest man in the world. You have achieved the perfect sleep score and you are changing what it means to live long and live well. I have a lot of friends who are big fans of yours and who try to live as close as possible to the blueprint method.

2:53and many of them happen to share similar outcomes of their work and success as you do and having exited companies and reached a point in their lives and careers where they have the luxury of time and resources to really go all out. And I have other friends as well who may not have the same resources and actually focus on the basics of sleep, exercise and eat that you you talk about very often. But I'd love to start our conversation by going back in time to what your life was like when you were a founder before you exited your startup, Braintree to PayPal. What was old Brian like? Yeah, I mean, I remember the bargain I did with myself.

3:39I, at the age of I was trying to imagine how much money would I need by the age 30 to stop working. And so I just pulled out a spreadsheet. I started doing some math. I assumed a 7 % interest rate. And at the time I assumed my monthly consumption would be something like$10 ,000 a month. That would be adequate for a family. I had, I planned on having a few kids. And so if I'm not mistaken, I believe the number I came up with was something like$7 million. If I got that, and we lived in a frugal way, it was enough money to basically never work again. And so I thought that's like the low end of the possibility, then of course, you can go up from there.

4:25And the contemplation was that if you were willing to devote yourself on that kind of journey, you could come up with zero, or get, you know, 7 million or more, but you basically were making that bargain. And so I remember the mentality in doing that was, I'm willing to sacrifice myself for this bargain, which means I know as an entrepreneur, you're going to have to work very hard, probably seven days a week, all day, every day. You probably are not going to take very many vacations. It's going to be on your mind all the time. Like it's going to be an all consuming thing. And I remember that was the mentality I had in going into it.

5:04So I knew it was a sacrifice. I knew it was a bargain and I knew I was going to have to pay a price. And so I just didn't even question what the price was. I just assumed that doing it would be somehow worth it because then you'd have this sometime horizon where you didn't need to play. So I guess that really my starting assumption baked in the fact that I was already willing to sacrifice myself for this objective. Fine. And I assume by sacrifice yourself, you mean not sleeping as well as you could have, not eating as well as you could have. Yeah. I mean, that's the bargain. So if you what I've learned is that when I share ideas about health and wellness and about, for example, like when I was speaking to a group on Saturday and I was trying to persuade them to make sleep their number one life priority.

5:55and I got people to raise their hands like who you know after this is like after 10 minutes of explaining the benefits and also the damage that your body incurs when not sleeping well and I would say like raise your hand who's willing to commit and I got quite a few people but then there's probably like 30 percent of people who are being intellectually honest they're like I can't and so I'd say okay what's what's your objection to this and so one one woman said well my children, they can't do it. They just, I said, why? And she said, they have too much to do, like too much homework, too much, you know, the sports activities after school, like how are they going to compete?

6:33And I was trying to figure out a way to articulate this, that in society, we've just assumed that if there's too much going on, sleep must be sacrificed. Instead of saying sleep is the non-negotiable and everything else must be planned around it. And then somebody who was a student at USC also raised his hand. He said, I can't because I'm a student and I'm trying to get my grades to compete. And so I guess in both those examples, people, they treat sleep as a variable that can be pushed around according to other fixed goals. And what I was suggesting to them is they need to fix sleep and other things, other variables they need to push around.

7:17And so as an entrepreneur at 21 years of age, I was basically accepting that societal assumption that I was willing to accept that sleep was a variable that I could push around because my goal was fixed. But it takes a long time for people to really think this through because it's so ingrained in us that we don't need sleep. It's not really important that it takes like several cycles to go through for someone to realize what they're actually doing. Absolutely. I mean, I'm incredibly curious about your transition from sacrificing your health for the sake of work to once you had accomplished your goal and exited your business and you were finally able to shift your priorities and realign your sacrifices.

8:00Was that an immediate change? I think it was gradual in its intensity. So a few things. One, we're all motivated to have good health because feeling crummy sucks and feeling great is something you cherish. But in between those two observations, it's not clear whether you like. So let's just say you make money and now you are evaluating your life. what's more important is it to have a great time with friends and party or is it to go to bed on time you have to weigh those two things and if the person says actually i'd rather have a good time with my friends and like i'm healthy all week long and then i want to party really hard because this is something i'm enjoying and if it somehow negatively affects my life uh like it takes a few years off my tail end of my life i don't care and so they use these thought patterns of like I can pay this price now because I don't care about my future self at some point in time.

9:07And so this is a second example where there's all these layers of cultural education we have, which blind us to this reality that actually those things don't make you happy. And so in my situation, I was going from depressed to not wanting to be depressed. That's a good one. but then going from there to where i'm at now is another really big leap and so i was just trying to say i don't want to be i don't want to hurt and suffer so once you get to some kind of neutral state then that's a contemplation of um what trade-offs are you willing to make and that's when the reason i got where i'm at now is that was the observation we are the first generation who won't die and once you get there then it's real then it's like this isn't some game we're playing And this is like the biggest game in the galaxy of like, we may not die, which means that I understand reality in a very different way.

10:08I definitely want to dive into that. But before we get there, I want to talk about this prioritizing health coolness and that shift that has happened recently where I'm privileged to know a few people that have exited and made a lot of money from selling their businesses, as you have. and five or ten years ago the natural next step after selling a business that i always saw was just maximum indulgence yes you know just party and eat and travel and do this whole thing right yeah and i see that changing where a lot of people are actually indulging less and caring for themselves more and that's what's cool yes and a whoop is a lot cooler than a lot of watches today and caring for yourself and caring about the quality and length of your life is one of the greatest luxuries.

11:03I think you're a part of that trend growth for sure. But why now? And why is it such a cool thing now, particularly for people who have the luxuries of time and money? Yeah. I mean, ultimately, humans respond to incentives. and it is currently not cool to be obese. It is not cool to drink alcohol. It's seen as it's not cool to, I guess in some circles, maybe to smoke, but generally speaking, it's not cool to smoke. And I'd say it is cool to flex biomarkers. It is cool to talk about what you're doing for your health. so i think humans are responding to cultural signals that you are higher status in your social group and your higher status in society if you can speak the language of longevity and you actually you embody it you know your skin looks great you have muscle you're fit it does really generate power and status and i think people respond to that and do you think anything has happened at a macro level to encourage that anything technologically yeah i think that uh what what's transpired is that um health has become measurable and so if someone's outwardly obese you know that's a uh that's a knock on them you know like They can't control their own eating habits.

12:39And so that's kind of like a source of shame. But if you're fit, like if you're relatively healthy, but you're unhealthy internally, no one sees that. And the fact that health can now be measured so robustly, it reveals your inner unhealth. And so I think that basically I would guess that there's been an accounting of health, that if you don't know your health markers, you're not viewed as intelligent as you could be if you knew your health markers. And if you do know your health markers and they're bad, that's kind of like being obese. Now if you have health markers and you're good, so my guess is that when people can hide something, that they'll scoot along and do it.

13:33You can still play the games of power and status just by faking it. But right now, it's harder to fake good health because the technology behind measurement is so much better. So you're about to make a trade based on a friend's text. But which you do you listen to? Is it, we could buy a house in Tulum. Get optioning those options. We could lose everything. or let's do a little research get your head in the trade and make the investment decision that's right for you learn more at finra.org slash trade smart and is that where your journey started you start that self-reflection and examination of your body to fix things entirely Yeah, I mean, the premise was that, like most humans, I ran my existence by my mind.

14:32You know, like, what does my mind want? When it looks at the menu at the restaurant, what does it want to eat? And when I think about whether I'm going to do this debaucherous thing, what does my mind tell me about my philosophies of life? And I said, the mind is not a good steward of the body. My mind is actually a really bad boss of my body. So I said, all right, body, you're in charge. So I'm going to ask you what you want to do by getting data from you, and you're going to tell me on a daily basis what to do and what not to do. And so I thought that the body is God in many ways. Before, you imagine this supernatural thing, and now the thing that houses our existence is our body.

15:19If we don't have our body, we have nothing. And so I think the body's been in this weird,

15:28like almost dismissed thing in our reality where it's like it's the flesh, it decays, and over time you can't stop it. But I think if we elevate it and imagine it to be sacred and a work of art and beautiful and like this magnificent creation that it is, it just changes how we think about it. So yeah, for me, it was putting my body in charge and realizing that my mind is a menace. I like that you said perfect the body. Because I think that longevity as a title and as a brand for this category is often misinterpreted. And people assume it means to live longer no matter the quality of life. Yes.

16:11and like like most old people who end up decaying and not not being in great shape before they pass they sure i'd rather not go through this another year than than be in the suffering i think people think about that when they assume what living longer in a bad way could look like versus living well so with your desires for this perfect body is it about added years or increased quality of life for the years that exist yeah it's about be sexy okay right be strong uh do what you want so even even these concepts lie that we use like longevity and no one cares right they just want to be attractive they want others to think they're attractive they want to have you know a good looking body they want to feel great they want to sleep great they want beautiful skin so like that's the language like that's what humans want now longevity is a byproduct of those things but just be sexy is what most people want and i know the fundamentals are the most important by far eat sleep exercise well and the enhancements that can be added on beyond the list is long and you are the leader of the pack with all the things you can do.

17:37If you were to stop everything except for the basics today, do you think that would have a significant negative impact on your biomarkers? I mean, probably. Yeah, so there's several big camps to health and wellness. And there's a big camp that believes in natural remedies. Like the idea is that it's been around for tens of thousands of years. Therefore, it's still the test of time. And therefore, we should do something like that. And then there's groups, there's people like me who we lean into medications, you know, any kind of technology we can get access to. Food plus exercise plus pharma kind of stuff we embrace.

18:24And so we have said that we don't judge any intervention by any modality. If it works, it works. And so for us, the goal is trying to basically establish a new world record, a new singular accomplishment on what can be done. and therefore we just pull out all the stops. So it's not like we're trying to be generally healthy or roughly healthy. It's like we want to have perfect health. And that's a pretty bold endeavor because we still probably are in the very early days of understanding biology and longevity. But yeah, so that's what we've done in doing that because we wanted to, a lot of people,

19:12in encountering this, a lot of people don't know where to find the motivation. So if like looking great is what, you know, the objective a lot of people align with, outside of that, they're not quite sure why do you try? Because if they're going to age and die anyways, is it really worth all the hassle? And I'm trying to give people a motivation to say, it's really worth it. You can meaningfully change how you feel like significantly. And that's why I want to create this contrast where people are like, okay, before I thought like maybe worth a little bit, but now I'm into it because you really can make big gains.

19:52So I'm trying to change more than anything the perception around health and why it's worth doing to a meaningful degree. Not just, I'm not arguing for a lackadaisical approach. I'm arguing a very robust, energetic disposition towards health, that it really is worth it at every layer. And how much stronger is the prioritization of prevention than fixing the problem once someone gets there and hoping for the progression of technology to come so far? Yeah. Because I know you are a technological optimist. you believe that a lot of the world's problems will be solved by super intelligence. What if this is one of those problems that could be solved?

20:36Yeah. So you see, like, actually, I think the most interesting pattern here is in your questions, you're correctly identifying the thought patterns people have that are the barrier for them to be, to make good health decisions. So this latest question you asked, the way people process that, and I have friends who say this, like certain friends who said, I've stopped doing things for my health because AI is going to solve it when it's here. One person said I stopped wearing sunscreen because when AI comes, it's going to fix all my sun damage. And that may be true. And the point I'm trying to make though is that the psychology behind that is actually the root of our problem as a species.

21:23Is if we apply that same theory of like, I'm going to pollute the earth because AI is just going to fix it. Or we're going to allow nation states to go to war with each other and kill each other because AI is going to come and fix it. If that becomes the way of managing our problems, we make our situation worse. And I'm trying to suggest the more healthy disposition is for us to say we are going to solve it right now, not just because it actually is beneficial for you now, but that is part of this larger philosophy of where we're at as a species in this moment. But you can see that the biggest foe I personally have in this endeavor is all the baked in ideas that humanity has accepted for their entire lifetimes.

22:11And these ideas challenge them and they can't see that they're actual blockers. Yeah. Where are we as a species in this moment? I think if we can survive this moment and future generations are writing the equivalent of history books about this moment, I think it's possible that they say that this was the most spectacular moment in all of intelligent existence on this planet. that when you're transitioning from human-based intelligence to digital intelligence, and there's this transition moment to something new, and it's perilous. It's not clear whether we're going to make it through this. And so I think that it's exciting beyond our ability to see that if we saw ourselves in this historical moment, we would behave with such different energy.

23:16Then right now, we kind of know something's going on, like a lot of people know something's going on, but it feels very much like we bring status quo-like energy to it, where it's like, it's going to happen and I'm going to observe it versus a very active approach engaging with it. As I look around your home, I see that it's actually a lot more analog, I mean that fully respectfully, than I expected from someone who's so AI and so much of a tech futurist. Is that a clear decision for your health and your routine? The way this house is organized is everything that causes death, we try to control.

24:05So the water you drink is filtered in a special way that produces, and we measure it every month to monitor those parameters. The air we're breathing is finely purified and measured in every room. these windows have UV 99 % protection from UVA, UVB so you can't see these things but these are the invisible forces that are affecting your biology in any given moment whereas the technology I could have in this house does very little to actually change my biology and in fact it might even make it worse more screens, more this, more that so I don't use a lot of technology outside of specific, in my clinic, for example, I have a lot of technology, but if it doesn't have the objective of extending lifespan, it lowers, increasing my health.

25:00Let me say that. It lowers in its likelihood of being in the house. Fine. So how bad is sun exposure for us in UVA and UVB? It's not bad. It's just that the sun is a trade-off. So the sun is good for you. It has all kinds of positive health benefits. It just is that it has a cost. It causes damage to the skin. And you can measure this. You can actually use this technology called multispectral imaging. And you can measure it and look at UV damage. So it's very clear what happens. So you're just in, I get a lot of flack because I don't spend a lot of time in the sun. and because of that people hate me because they have such a firm belief that the sun is the most important thing in existence and if they do, that's great.

25:53I encourage them to be in the sun and that's wonderful. I'm saying that the flip side of the argument which they don't acknowledge is that the sun causes damage and I don't want to make that trade-off. So this is the same thing as if you drink alcohol you're accepting that damage. If you smoke, you're accepting the damage. So it's a similar damage assessment and trade-off space. And so I'm just saying that I'm aware of the damage that it caused me. I can practically measure it. And therefore I choose not to make that trade-off. For sure. How much of an edge do you think people can have by optimizing for the place they live on a national level or even on an urban level?

26:34Because you live in Los Angeles. Yeah. Which I find to be a choice I wouldn't expect because of the air quality and maybe the water quality and different things. Do you think people can have a significant edge by moving to somewhere like Switzerland? Yeah, possibly. Yeah, I chose to live in LA for a few reasons. It was actually a decision I made seven years ago. So I had sold my company, Braintreeve Emo, and I built that company in Chicago. We had offices in San Francisco. I then lived in Virginia for a year or two. I lived in New York and then San Francisco and then LA. And at the time I was trying to optimize for two things.

27:16One is I was building a brain implant interface company. And so I was trying to figure out whether to do invasive, to implant a chip in the brain or to do something non-invasive. And I didn't know which path we were going to take and I needed some flexibility. And so in doing that in 2017, there were only really four markets in the U.S. that had the talent and the density of institutions to do this. It was Boston, New York, San Francisco, or L.A. It was hard to find. You couldn't go. It's harder to go to a second tier or third tier market and find the density of engineers because you need engineers that are very specialized in a whole bunch of different areas.

27:58And so that's why I was going through those different markets. I lived in New York for a while. Same with San Francisco and the same with Los Angeles. And then the second thing I was trying to optimize for is that I was really, while I had done this venture investing into deep tech, like synthetic biology and genomics, and then I was doing this kernel company, I was also pursuing this idea that I wanted to try to find an idea that would be relevant in the eyes of those that exist in the 25th century. I wanted to kind of try to play reality on a few hundred year timescale. And to do that, I imagined I need to find something very novel.

28:42And in sampling New York and Boston, and Boston's also a market could have built a brain interface company, which is way too cold though. And also, well, the other dropouts there. But I realized, so I was trying to analyze these areas and in each one of these areas, there's a very strong social zeitgeist on how people think and what they're into. And I basically concluded that Los Angeles was the most open of all possible places I could live. That would be the least intrusive on my own thoughts and give me the most space to play. And that's why I chose LA. I didn't choose LA. I wasn't into longevity at that time.

29:25so I didn't decide it. And then now I've kind of built a home here. We have a lot of friends. So it's a different calculation. If I would choose him based upon longevity alone, it would be a different calculation. So yeah, I'm open to it, but I'm here because of a previous thought pattern. Fine. And as part of that thought pattern, you mentioned hanging out with friends. I try my best to sleep as early as I can. Some of my friends call that antisocial behavior because I can't hang out with them when they're free to hang out. How does that look for you? Yeah, this is again, this is like number seven thought pattern that is in between us and health.

30:02So the assumption that friends are making is that life cannot somehow be organized. Like it's a impossibility to hang out at times that are not late. evening yeah but it's actually not true like we do things in life all the time at different times of the day it is entirely possible it's just that it's sometimes not aligned with mass societal cultural things and so it really is a lack of priority and not an insurmountable problem and this is why we build the don't die community is that a lot of people do want to choose health and they don't feel supported by their friends. And they sometimes get a really, they get a lot of trouble for it.

30:53All the little nuances of if they take pills, for example, or they choose to work out or they do cold plunge or sauna or like take whatever thing the person's doing, they get ribbed for it a little bit. And if they, you know, they're mindful of what they eat at the restaurant. Yeah, so there's just so many vectors for people too. I think what's happening is most people know what kinds of decisions they need to have to have good health. And when someone deviates from that approach, it makes them feel uncomfortable because they know that's the correct decision, but they don't want to reconcile with that.

31:34And the friend calls them out on the behavior, and then they feel very uncomfortable. And so the best way they can deal with it is by trying to get you to stop that health forward behavior because it's uncomfortable for them to exist in deciding to choose bad health over good health. Like the peer pressure of why is the sober guy not drinking? Yeah, exactly. It makes everyone feel uncomfortable. I think that's why I generate so much intense hate is I think that my decisions are in contrast to the social norms and it makes people feel very uncomfortable. I try to do the same thing online intentionally.

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32:12My entire page is built on this fictional character that I coined, who basically, in some ways gives good advice, but in many ways, embodies the habits that I'd love to see people change. So I try to do the same online. Cool. I mean, with your businesses that you're working on today, with Project Blueprint and with Don't Die, are they businesses and movements that you coined after solving for yourself because you want other people to have the same rewards that you felt on working on yourself? Or is it a project that you ideated first and you're using yourself as your kind of guinea pig for the sake of the rest of humanity?

32:59Both. The goal would be something like in 2027 or 2028 or even like 20, 20, 30. It's like somewhere in the next couple of years. If something like 80 % of humanity said in unison, we don't want to die right now. Like all the crazy stuff happening in the world right now, we just don't want to die. And so that's what the world said in response to COVID. and that's why we had such a quick reaction all the lockdowns happened and the masks and vaccines say what you will about those things but the world basically said in unison we don't want to die right now and that was cool because we saw people act in unison across the globe mostly for the most part like this we want to figure out the situation and i want i think ai progress is going going to create a very similar situation for us humans it's going to be moving very fast and in ways we can't quite comprehend and it's going to be very unsettling and in that moment we're going to panic and we're going to say i no longer know who do i trust is it my government or is it the ai when i'm being fed information who's it from is it the ai or humans and we're just we're not going to be able to discern what reality we trust anywhere.

34:26And now, so if you take that and you back up and you say, okay, now what do you do right now that allows humans to be, to say in unison, we don't want to die and we want the world to actually support life. Then it begins with a personal habit where I say, going to bed on time is a good idea. Even if you haven't finished your homework it's the correct idea and you take all the things we talked about and those decisions then have this domino effect where then you say okay polluting the earth is not a good idea not now and not even expecting ai to clean this up and you keep on going down the line and then finally we say it makes a lot of sense to engineer ai to don't die with humans and it makes sense that we actually say we are at war with death in all of its forms and therefore we choose life over all things and so that's what i'm trying to do is it's it's a business it's a philosophy it's a religion it's a nation state it's everything it's like how do you move the species to march to the same cadence and that's what we're trying to do so it's all things happening simultaneously And is there a particular age or life experience that you think is helpful to be able to march at the cadence that you think is appropriate?

35:55There's a few archetypes that respond really well to don't die. One is people in their 50s, 60s, they're beginning to experience aging decline. And they know what it feels like for the body and mind to fall apart. and they are incredibly motivated. Another group, those who've had near-death experiences, either with a health scare or something else, they just value life with this intensity where they really, really appreciate that they're alive. And then younger people, they hear these ideas and they're like, this is banger. Like, this is fire. This hits. This makes sense of reality. Where I find the myths is people who are in their mid to late 20s, 30s, and even early 40s where their health is okay and they're locked in on other games like ambition or something else where they're like, eh, I'm willing to live 10 years less in exchange for whatever tradeoff they're making.

37:03I also find that when we went to India and China, they ate this up. They thought, this is so sensible. This actually makes a lot of sense on how we deal with this situation as a species. Whereas in America, there's a lot of individualism. A lot of Americans are kind of like, F off. Don't tell me what to do. Don't tread on me. So Americans are very defiant, but Indian and Asian cultures were very supportive. So it's like now I've spoken about this for long enough. I know the archetype and the response. Just it's so predictable. You tell me the archetype, I'll tell you exactly how you're going to think about these ideas.

37:40Fine. Yeah. And are there any scale hacks through authority that you think could help this grow a lot faster as well? Like education possibly? We're trying to find those growth factors. The ones I think that have the highest potential are the non-serious ones. So it's this idea of be sexy. It's like if something, like if Kim Kardashian was basically a proponent of don't die, it was just like, look good. That really resonates. And something like, you know, don't eat sugar. That's bad for you. There's a path here with memes, you know, that that's very powerful. but I would say like things that are serious in nature have, I think a limited reach, but also I think like legislation could also be useful.

38:34Like legislation is like very functional. So, but it's just very hard to like, for example, if we say let's outlaw alcohol because it's bad, that's a really bad idea. You don't want to have to rally people. You want to get people to not drink alcohol, because it improves their status and power. So you really want to come to the front door of making a positive pitch than trying to go after the negative. I mean, I actually see that happening with saunas and cold plunges. It has this status that comes with it now of it's just a cool thing to do. It's a thing successful people do. I think the glamorization of being in good shape and taking care of yourself is the hack to scale for this.

39:24Yeah. I mean, I would imagine if somebody is doing something like cold plunging or like sauna, you can probably, with a stopwatch, the moment you meet them, start it and just clock the time it takes them to tell you they're cold plunging. Tell you they're doing it. 100%. So it's really, really powerful. It's a social signaler. It's true. And so you probably, to find what is culturally on point, you just need to watch the word mapping of what's dropped on new interactions and when. And then you get the status ranking of what ideas increase status the most and the fastest. As part of my day-to-day job, I have to study the lifestyles and patterns of my audience who happen to be some of the world's wealthiest people.

40:22And I'm seeing this growing pattern of people doing less indulgence and more self-care with their trips. And from going to beautiful health clinics to even traveling and playing paddle and doing sauna and cold plunges instead of traveling, going to clubs and drinking and doing all those different things. And I'm noticing that it also comes with bragging rights that for the first time in that community are actually positive. I think that the brag of rich people doing rich things was always like a pretty awful thing for society generally. But now the brag is actually pretty good because the guy who's addicted to saunas and cold plunge, who can't stop talking about it, is actually encouraging positive behaviors.

41:13I think where this is going is that directionally, so health is being broadcasted as a status signal. And I think where we're going next is that certain biomarkers. So right now it would be, you can say things at the abstraction layer like eye cold plunge or eye sauna. The next layer is going to be talking about things like your speed of aging. that looking at DNA methylation clocks, you have a number. Or speaking about your biomarkers with a certain level of fluency, like my cholesterol numbers are blank and my plaque score is blank. So just like one layer deeper where it shows not only do they practice health, but they measure health.

42:02And then the next layer is on some kind of comparison and leaderboard. This is what I did several years ago where I was trying to appeal to people who were engaged in health and wellness, but the problem was everybody could say what they were doing and earn the same level of respect. But that didn't tease out that there were actually ways to discern who was actually more efficacious in what they were doing. And so I created the rejuvenationolympics.com, a leaderboard where people can compete for the lowest speed of aging using these uh dna methylation clocks okay uh and so it's been going on for several years now and people have gone nuts over this like anytime you create a sport and you create a leaderboard and where you have points humans kind of go crazy so it's been this unbelievably successful endeavor where uh People are all out competing.

43:06And so I think that's probably where this steps to next is people are legitimately competing on biomarkers for status. And you're number one on the leaderboard. I am. And always have been. No, no, actually. I haven't for a while. I haven't been number one. So this is the whole point. So I created this to say basically what we've carved out is a way to be healthy, but certainly there's other ways too. And so I want to make a leaderboard. And so when you get on the leaderboard, the invitation is share your protocol. So educate the entire community on what you're doing. So everybody improves. And of course, like most people keep everything a secret, as you might expect.

43:49They're trying to retain their competitive edge. But yeah, so for several, for the past year or so, I haven't been number one. So we've been working very hard at it. and so yeah it's been great in that it really encouraged quantified competition so you can tell who's the best so yeah i'm currently number one in the world there's 6 000 people who are intensely competing for this objective i mean the one thing i would love to know about that on that leaderboard i don't know if it's if it's on there if it can be quantified but i'm very curious about biological clock and speed of aging in proportion to time spent and dollars spent as well.

44:29Agreed. I assume there's a point where it gets very expensive to have like less of an impact and the sweet spot of like the 80 % prior can be incredibly inspiring to more of the world. Yeah. It also has revealed, it does that also, it shows genetically gifted. Fine. So it shows some people who participate on a whim and they do very minimal efforts. Like they have, you know, they try to eat well, but like sometimes they're eating fast food, sometimes work out, but not really regularly. And they have one of the better speed of aging scores. And so it does in that way, in that going back to the story before of like, I have an uncle who blank and blank and blank, and therefore I should too.

45:12that teases out from this one-dimensional measurement what are your genetics in terms of how fast or how slow you're aging so that then can inform them maybe it's not a good idea for you to follow the whiskey smoking whole bar chocolate everyday protocol that may not be your jam so yeah there's so many layers of benefits so yeah I would imagine your audience is going to step from social signaling too fluency with markers, too competing on markers. That they, like me, they publish their markers and say, here's where I'm at. And what we're trying to do with our community is we're trying to say, beat me, beat Brian Johnson.

45:54And that's the goal. And so I'm willing to share with them what I do so they can beat me. People will call me, they'll be like, I'm gonna get you. And I'm like, great, I'll help you get me. So I really want the whole field to improve. And we'll do that by sharing stuff. It doesn't make sense to try to partition off the knowledge. Sure. I mean, I have one of my closest friends is based in Switzerland and he shows off his biomarkers on his stories with the intention and hope to encourage people to do a similar thing. And he actually got his kids on the journey too. Yeah. They do the basics, but it's really cool to see him setting trends.

46:31And I see people replying to his stuff and it's really a thing for sure. I guess what you're saying about the people who have the genetic disposition to be on a better beginning, the change of where they started to where they got is probably the most interesting part in that case. I mean, I think I should probably start doing some measurements myself. Yeah. What have you measured? Honestly, not much. Is that right? I've never measured my sleep. I've never worn a whoop or an aura ring. I know when I sleep. I guess the measurement is my mind, which you said is probably the unhealthiest way to go about it.

47:11But I haven't quantified these things. I think I'm reasonably healthy and I'm reasonably mindful about what works for me. But I think backing my decisions with numbers would probably be a good thing. Have you gotten a blood draw? I've had blood tests, but by medical doctors. And have you seen the results? I have. Yeah. And have you? They seem okay. The doctor's like, yeah, you seem like a normal dude. Yeah. So what's your chronological age? I don't know that. No, like how old are you? Oh, how old am I actually? 28. I do know that. Yeah. So like at 28, I agree that the assumption is, right, that you are reasonably healthy because you feel reasonably well and you think you sleep, whatever.

47:58That's maybe true. It may not be true. And so this is a thing where most people in their 20s and 30s fall prey to this kind of thinking, is you kind of don't think bad things are going to happen to you, at least at this age. And bad things could be happening to you, and you just don't know. And so, yeah, that's one of the common misperceptions. And so if you do a basic blood draw and then take those results and run it through ChatGPT and just say, how am I doing? Is there anything alarming here? I wouldn't trust your doctor to come back and give you the news. I know in previous times when, like when I've been doing blueprint, I worked with a lot of doctors and some are into, you know, like anti-aging, some are not.

48:46So one doctor in particular, he runs this high end concierge group. And something happened. Oh, I remember like my inflammation score came back very high because I had been injured. And so my body had reacted, but I didn't tell him that when I saw him. And so my numbers came back very high, but it was still like roughly in like the tolerable range. And he got my results back and he's like, great, keep on going. But if you look at the numbers more closely, I definitely would have said that is a big problem. Like what is going on? But so they, they really have a set of standards that may not necessarily be the correct standards because they're accustomed to looking for gigantic problems.

49:33And if they're not a gigantic problem, like, yeah, just kind of push it away. So yeah, I would suggest it's never too early or you're never, there's never a good excuse for not knowing the data you want to be. Yeah. It's much easier to address practically than being caught up trying to fix a problem. This episode is brought to you by White Claw Surge. Nice choice hitting up this podcast. No surprises. You're all about diving into tastes everyone in the room can enjoy. Just like White Claw Surge. It's for celebrating those moments when connections have been made and the night's just begun. With bold flavors and 8 % alcohol by volume, unleash the night.

50:11Unleash White Claw Surge. Please drink responsibly. Hard Seltzer with flavors. 8 % alcohol by volume. White Claw Seltzer Works. Chicago, Illinois. One thing I love that you spoke about is the extra virgin olive oil. that I feel like it's such an incredibly simple and actually delicious fix to people's lives. And you did say that extra virgin olive oil is better than Ozempic for weight loss. I'd love to hear more about that. Yeah, so I should clarify that. What I was trying to say is that olive oil has many beneficial health properties and some of the same endpoints as Ozempic. Ozempic is clearly better at weight loss and appetite suppression than olive oil.

50:57But what I was trying to say is Ozempic is top of mind for people on a singular solution towards appetite suppression and weight loss. And extra virgin olive oil has some similar mechanisms that achieve similar results. So I was just trying to draw a contrast that when you're thinking about what things to do, in certain situations, Ozempic is definitely the move. Like, do that because it's singularly good at that. Also, extra virgin olive oil, these natural foods do have very positive effects on controlling appetite, on helping with weight loss. So, yeah, I think that I was trying to communicate that foods are very effective at doing things that people think drugs only can do.

51:41but actually you can have a portfolio approach in doing it so fine i mean on the slide guy podcast we always conclude with a simple finale question on my instagram i always talk about things that are a la poubelle which in french means to the trash things we'd like to change and things that are fantastique which are things that we love is there one thing that you find or one or two things that you find to be particularly a la poubelle today in the world around you or the society we find ourselves in and one thing that is particularly fantastique and great that you're grateful for yeah okay first what we put in the trash yes i think that we should stop following our minds and instead follow our bodies that is if you think about your decisions on a daily basis you're mostly most everyone is run by their minds it's what your mind wants it's what your mind um has a yeah versus legitimately saying body you're in control so i think that that is a revolutionary idea that is offensive to a lot of people because most people understand themselves and their existence through their mind through their preferences this is when we talk about like extreme longevity, like, you know, going on some duration of time, again, the rebuttal the person has is, I don't want to live that long because I'd be bored.

53:16And so to me, that answer basically demonstrates why the mind should never be in charge of longevity. The mind has no idea how to think about the future. The mind is willing to make really stupid errors of logic that, basically they're saying when I'm 80 years old I'm somehow not going to value life as much when in fact it's probably more than ever but when you arrive at 80 you don't want to die when you're 80 so people are incoherent with their existence so I would put that in the trash and say at this moment as a species we should transition from mind to body it is in our best interest our body is more wise than our mind in the fundamentals of life and that we should fully embrace that as a shift in our shared conscious experience.

54:13I love that. And something that is fantastic and great. We would be legitimate in having a child-like excitement for this special moment that we're in. It's almost like if you traveled back in time to a caveman and you're like, if you just hold on a little bit, you're going to be transported into a world where you have glowing objects, but you can speak to anybody. You have these little white pills that solve infection. If you break a bone, it gets fixed. You're going to sleep in a warm bed, have a warm shower. You know, like, just hold on. I think that it's the eve of something so spectacular we can't even imagine it.

55:09And I think we can look at this possibility with childlike wonder and childlike enthusiasm. And in doing this, it helps motivate us through these day-to-day decisions we have to make. Take, for example, if you're just in this moment right now, do you drink with the friends or not? That's just one decision. You may say, just tonight and then the rest of the week I'm going to be healthy. Those kinds of decisions relative to a childlike wonder of an extraordinary existence, it just makes that decision so easy. I'm not going to drink because that's silly. And this is one of the cusp of the most extraordinary existence in this part of the galaxy.

55:49That's so silly. Why would I make that tradeoff? So it's that kind of comparison. So I think this is, to me, what's so motivating and fantastic is that we really, it warrants having that kind of enthusiasm and hope for the future. And it's ours to build. We just need to say yes to this moment. It would be like the biggest loss of opportunity in history if we actually don't succeed in this moment. I love that. Well, thank you so much, Brian. Thank you for your time. And thank you for having us in your home. Thanks for being here. Thank you. Thank you for listening to this episode of the Start Guy podcast.

56:29If you're keen to learn more, please follow along by engaging with our social channels on Instagram, TikTok, Spotify, YouTube and Apple podcasts. And we look forward to seeing you next week. Merci beaucoup. A la prochaine and a big hug from the Start Guy.

From the publisher

In this episode, The Gstaad Guy sits down with tech entrepreneur and human optimisation pioneer Bryan Johnson to explore the ideas, trade-offs, and motivations behind Blueprint, his controversial and cutting-edge protocol to reverse ageing and extend biological youth.

The conversation unpacks the science of longevity, the measurable impact of sleep, nutrition, and cellular regeneration, and how our perception of health is being completely redefined by technology. Bryan speaks openly about the sacrifices behind his routine, the psychology of motivation, and the role of superintelligence in reshaping not just what we do, but who we are.


(00:00) Intro ✨

(02:52) Former Life ⏪👤

(05:05) The Bargain 🤝🏻👌🏼

(06:07) Sleep 😴

(07:15) Health vs. Work 🍎💊💼

(10:11) Health Is Cool 🍎😎

(13:14) The Journey 🚗

(14:08) “The body is god” 👤👑

(15:37) “Added years or quality of life?” 📅🧘🏻

(16:39) “Stopping everything” ✋🏻🛑

(19:35) “Superintelligence & health problems” 🧠😷

(21:20) “Where are we as a species?” ❓🧑‍🤝‍🧑

(24:06) “Sun exposure” ☀️

(25:44) “Where to live”📍🏠

(28:43) “Sleep is antisocial” 😴🤐

(30:12) “Health decisions” 🍎🤔

(34:56) “Archetypes of Don’t Die” 🦁💊

(36:42) Growth Vectors 📈

(40:18) “Health as a status signal” 🍎✅

(43:13) “Speed of aging” ⏳👴🏻👵🏻

(46:50) “Bad things can happen” ☣️

(49:02) Extra Virgin Olive Oil 🫒🫙

(50:17) À La Poubelle vs. Fantastique 🗑️✨  

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