214. Methylation Test Explained: Stop Guessing What Supplements You Need

28:44And so that's the morning routine. These, by the way, are all available in health. So in the UK, you can now get all of these on health. You can actually leave this room with samples of all of them. I invite you to just take them home. Try that first thing in the morning tomorrow. Don't change anything else about your routine other than adding all nine of the essential amino acids, all 91 minerals, and hydrogen gas to your water first thing in the morning and you let me know how you feel. Watch the lights come on. And the final thing was to offer the DNA testing to everyone in this room at 50 % off.

29:24Before you leave here, I'm launching this gene test in the United Kingdom on November 1st. But at this event, you can get it for half off. And that test will tell you exactly what your body is deficient in. So you will no longer guess what you need to supplement with. You will stop supplementing for the sake of supplementing, and you will start, maybe for the first time in your adult lifetime, supplementing for deficiency. I promise you this is where the magic happens in human beings, giving the body the raw material that it needs to do its job. That is why I am so fascinated and compelled to dedicate my entire adult lifetime to the study of genetic methylation.

30:03So the funnest part that I get to do, By the way, if you get the genetic test while you're here, I'm actually giving away a cold punch. We had somebody win a cold punch yesterday.

30:13Gary Brecka:Is there anyone from my staff that has the name? Malia or Brianna? Okay. If we find somebody from my staff, somebody come bring me the name. I'll tell you who won one of the cold punches. And if you're really brave, we actually have bathing suits. We have onesies for, wait, wait, onesie is for baby, right? One piece. We have one pieces for women. we have onesies too but we have one pieces for women that you can actually take home with you and we have shorts for men so if you want to actually do a cold plunge which is my I call it my drug of choice because it will raise your dopamine it will raise your norepinephrine it will activate a really interesting thermostat in your body called brown fat which actually exchanges a calorie for a measure of heat it will dump cold shock proteins into your blood, which will scour your blood of free radical oxidation, improve the rate of protein synthesis.

31:09Gary Brecka:The cold shock proteins are a fascinating new area of science. It will cause a peripheral vasoconstriction that dumps blood into your core. I call it my drug of choice for a reason. So if you want to take my drug of choice, it's right back in that little cabin back there. There's changing rooms. You're welcome to do a cold plunge. Yes. Roger Guy.

31:33Gary Brecka:Oh, he bought 10 methylation tests last night, so no wonder he won the methylation test. It was randomized, but he bought 10. Okay, so Roger Guy. Does anybody know Roger Guy? Okay, is that you? You're Roger Guy? All right, well, you just won a cold plunge, my friend. All right.

31:52Gary Brecka:So I want to bring up our lab partner from the United Kingdom. Come on up here. Say hello. Hi, guys. So this is our The lab partner that we partner with In the United Kingdom I want to show you Do we have someone here that's volunteered to take a gene test? We do Oh you're right there? Come on up here First of all do you mind just doing this test In front of the whole room? Okay We won't publish your results It'll get destroyed and we'll give you a real one So if you could just walk her through Taking that test Yeah, absolutely. Hi, guys. I'm Leila Sertel. I'm the CEO of Optinly Me, and we're so excited to have you, Gary, and team in the UK and to finally be able to talk about this test, which we've been hard at work on for a very long time.

32:41So thank you for agreeing to be our live guinea pig. Can you tell the audience your name? I think we also need to get you a mic, maybe.

32:53Yeah. Or you can project. I don't know how loud your voice is. And as soon as this test is over, I'm going to open it for questions. And I really want to engage with you on what you or your loved ones are facing and why or how methylation might be the answer to that. Hi, my name is Agnes. Amazing. Have you been paid, Agnes? Sorry? Have you been paid to be a spokesperson? No. Okay. We should be. Test before? No. Okay. But it's only the reason why we're here. Because you announced the launch. So we decided, yeah, we have to buy tickets and come here.

33:28Gary Brecka:Oh, thank you. It's amazing. Well, I don't think you'll be disappointed. Fingers crossed. Brilliant. So we are going to walk you through how to do a test live. Optimally Me provides diagnostics as a service. So we are an end-to-end solution for anyone wanting to do all types of different at-home testing. And so this is done digitally. So you get a physical kit in the mail if you buy it from Health or you go take one home today. And when this arrives, you will be asked to activate your test kit. So here, I'm going to give this to you. I can hold the mic for a second. You want to show the audience how it slides in and out.

34:02We're quite proud of that design. Smooth, nifty.

34:08Brilliant. So normally at home, you would do a digital activation. It's super simple. You scan a QR code, you put in your first name, last name, email, birth date, and that activates your account. and then to do the test physically, we ask that you don't chew gum, eat or drink for an hour before because I can interfere with the samples. No problem if you haven't followed that because we will give you a fresh test to go and do at home. So brilliant. Shall we sit or stand? I'm thinking maybe we sit down here. Why don't you sit? Okay. So you take it out. There are instructions for use inside And something to mention that we took very seriously is we work with a handful of labs, and they have to have best-in-class accreditation.

34:55So they have all the mandatory plus optional accreditations to make sure that the machines they use are being operated properly, their facilities are run to a certain standard, and the results delivery come in terms of a certain file format with certain data protection measures in place as well. We're not selling your genetic code to China. No. And actually, something that I was saying to Gary before we spoke is, this is going to get a little wonky and technical, but OptimallyMe uses a unique sample ID. That links your data up in the back end when you go in and you get your results. But to the lab, they're actually getting a barcode, which doesn't even have that.

35:33So literally, none of your personal data goes to the lab. They just get the swab with that barcode, and then it gets destroyed after. So we're taking data protection very seriously and making sure that we don't send any personal information that doesn't need to be sent. Yeah. Okay. All right, let's swap. So let's swap. So these are your instructions. You would fill this out with what day you took the sample on. I'm going to put some of this here. And then if you'll hold this for me, it comes with a return shipping label. So it's super easy. You just pop it in the mail. And then if you'll take out the buccal swab, show the audience.

36:08So it's literally this is how you do it. And that's the return. So what we're gonna do is we're gonna ask you to do the buccal swab in your cheek for one minute. Something to note. So you open that and the thing to be careful with is just don't get that Q-tip looking end wet because that's or like on anything. So keep it clean and sanitary because that's what actually swabs your cheeks and that's where they process the sample from. So I'm gonna pull this open for you. You're going to make sure it doesn't fall on the floor. Normally, we'd have a table.

36:44So the barcode, this is the barcode I was talking about. Hold that. Take that out. Oh, yeah. Good catch. Good catch. Okay. And then I'm going to hold the end of this. I'm going to ask you to hold the end. And you just literally swab the inside of your cheek, rotating it for one minute. Does anyone have a timer? Who wants to set a 60-second timer for us? I see lots of people in the audience. He's got it. He's got it. Thank you.

37:12Okay. So you just rub it around?

37:16Gary Brecka:Longest minute of your life. Swabbing your cheek in front of 400 people. Nothing embarrassing about this. Nobody's looking at you. But she's doing a great job, guys. So you want to push firmly against your cheek and rotate it. And what we also recommend is just swishing your mouth out with water before you do it, because that just gives it an extra clean. But really simple, very straightforward. This is probably the hardest part. And then making sure that you package it and put it in the box, right? You said you don't drink an hour before my spoon, you're okay. So before, no, we don't want you to have water, but before you can do a swish with water.

37:56Yeah, spit back. That's because, so while she's swabbing, you'll update us as we get closer to the minute. Five, four, three, two, one. All right, you're done. Okay, perfect. Beats a blood test. Yeah, it's easier than a blood test, although we make those easy, too. So now you're going to drop that in with the buccal swab and burst, making sure not to touch it. Perfect. fold that over and I ask you to seal that with the barcode so just tape it shut

38:39and then drop that in here

38:46and then it's done so she's now done the test and we'll get all of this information Thank you so much for being our live guinea pig. So this then goes in, you stick, so actually, actually, while you're all watching, you stick this in the box, which is behind you. This, you know what, this is probably the hardest step. You stick the sample back in the box, and then you make sure to put the box in the return envelope and send it on back. So we will get you a test to do at home to make sure that you can activate your account. And then you get all of your results in an incredible interactive dashboard with videos from Gary, recommendations from Gary around everything he's been talking about.

39:34And you will never guess again on what your body needs to supplement with. Once you fix the deficiency, then you can move on to supplementing with targeted things for other items. You can take resveratrol or CoQ10 or St. John's Ward or ashwagandha or any number of other substances, NMN or NAD or nicotinamide riboside. But until you supplement for deficiency, those will never be the answer. Thank you so much. All right.

39:59Gary Brecka:You're amazing. So I wanted to take questions either about the test or the testing or yes, sir. Said he has a high ESR and they've told him to take a steroid. Yeah. called... Methotrexate? Sulfazine? Yeah. Sulfalocine. So I suggested that he didn't take it, but I'm just curious what your thoughts are. Yeah, so the interesting thing about steroids, specifically methotrexate, but also other steroids, like prednisone, methylprednisone, and corticosteroids in general, is that these actually give you a gene mutation that you don't have. They give you a synthetic gene mutation. They immediately inhibit the ability for the body to process folic acid and folate.

40:43And that doesn't sound like a big deal until you realize that folic acid is the most prevalent nutrient in the human diet. Folic acid is also an entirely man-made chemical. Folic acid does not exist anywhere on the surface of the earth. You cannot find folic acid in nature. Folate exists in nature. But when you impair the ability for the body to convert folate and folic acid into the form the body can use, which is called methylfolate, you now have a deficiency in methylfolate. So what are the consequences of a deficiency in methylfolate? I can absolutely assure you, your dad has gut issues. So he is either having gas, bloating, diarrhea, constipation, irritability, or cramping, or some combination of all of those.

41:26the most common complaint about steroids corticosteroids not bodybuilding steroids is our gut related issues so it slows the motility of the gut it actually messes up this pace of the gut and i believe that the pace of the gut is the most overlooked thing in all of modern medicine we think about the gut microbiome we think about the food allergies and food sensitivities but we do not think about the speed that the gut is supposed to travel and it's extraordinarily important that the intestine move at the same rate all the time. If it pauses, you get constipation. If it accelerates, you get diarrhea.

42:02If it actually stops, you get putrefaction. You get things like diverticulitis, ulcerative colitis. Eventually, the immune system gets called to these locations, and you get told you have Crohn's disease. You have an autoimmune condition. And this is where the symptomology comes from, the lack of proper motility. If you're not having about movement every single day, usually within 45 minutes of waking, that's when we need to turn attention to the gut. That's the first sign that your gut could be the root cause of what is ailing you. So ankylosing spondylitis is not directly autoimmune, but it's caused by a precipitating autoimmune condition.

42:40And one of the things that I say about autoimmune in general, so if you are suffering from or know someone who's suffering from an autoimmune disease and it is idiopathic, It's of unknown origin. I wouldn't accept that diagnosis until I had tested for these four things. So if you have or know someone that has autoimmune, please write these down. Mold mycotoxin, parasite, virus, and heavy metal. If you eliminate those four big categories of immune adjutants, you would eliminate the four biggest reasons why the immune system is called to certain tissue. In my previous talk, I talked about how if this were a mold or a mycotoxin, or this was a virus, or this was a heavy metal, and this was a healthy cell, this would not hide like this.

43:28It would hide like this. Does that make sense? Right? And so the immune system, which is hypervigilant, is after that, but has to go through this wall of a healthy cell. And one of the ways a hypervigilant immune system goes after a pathogen is it manufactures an antibody to the site where the pathogen is hiding. Interestingly, in the autopsies of 100 % of multiple sclerosis patients, they found the same helminth parasite, the same cestodematode, a corkscrew nematode that is corkscrew burrowed into the myelin sheath, lighting up the immune system in that location. right so now you have multiple scleroses multiple scabs or sores called multiple sclerosis and we're told that the immune system is attacking the myelin sheath for no reason well if it's attacking the myelin sheath why isn't it uniformly dissolving all of the myelin in the body why is it only firing arrows into the myelin sheath or maybe that is the site location of a parasite yes ma 'am The family member has sarcoidosis.

44:34Sarcoidosis, the same applies. In non-autoimmune, things like non-autoimmune psoriasis or eczema, these are waste elimination issues where the skin is used as a secondary route of waste elimination. But in perfected autoimmune conditions, especially ones that are idiopathic of unknown origin, I would really be testing for a pathogenic origin. I think the first mistake that we make is we say, you know what, I'm sorry, the immune system has made a mistake. We don't know why, but we are now going to punish the immune system. We're now going to put you on immunosuppressants or corticosteroids or anti-inflammatories to treat the immune system's response to attacking your tissue.

45:19But the question is, what called the immune system to that location?

45:23Gary Brecka:Rarely does the immune system just show up for no reason and start a fight inside of a healthy tissue in your body, especially in a healthy organism, a healthy biome. And the vast majority of autoimmune is in women. Women are 82 % more likely to get autoimmune disease than men. And why is that? Because the weaker the immune system, the more likely it is to malfunction. And weak immune systems are the byproduct of chronic stress. Women have a tendency to have something called caregiver syndrome, which is where they put the needs of others before the needs of themselves. Because they're meant to bear children, they're very often gifted with that ability, but they're also cursed with that ability.

46:03And they spend a lifetime putting the needs of other people before the needs of themselves, and eventually this causes a progressive weakening of the immune system. They don't take a lot of time for self-care, and the immune system stays in a stressed state. The autonomic nervous system stays in a state called a sympathetic state, which is a state of fight or flight, not a state of rest and digest. And this lays fertile ground for autoimmune. Yes. Can I repeat the four testing? Yes. Mold mycotoxin, parasite, virus, heavy metal. You know, in the last year, I will just say this. I'm not saying this is the genesis of all of these diseases.

46:39But in the last year, our clinic director, Dr. Carrie Sarda, and I, I don't have patients. I'm not a physician. She does. But three patients that came through our clinic system that were diagnosed with Parkinson's did not have Parkinson's. They had chronic West Nile infections. West Nile is a viral infection that you get from a Zika mosquito. As it turns out, in Miami Beach in Florida, it was like the West Nile capital of the world about 10, 11 years ago. They actually stopped pregnant women from traveling to Miami Beach for a short period of time. And it was a Brazilian mosquito and it had a massive outbreak in this area of Miami Beach.

47:15and West Nile became very prolific. If you actually look at the parallel symptomology of a lot of viral pathogens, it parallels a lot of very advanced neuropathic disorders. So how does Parkinson's start? Pill-rolling tremor. Then you get something called dysdiaticokinesias, and then it goes to something called flexor dystonia, where the flexor muscles begin to shorten. The mood starts to flatten. If you look at the symptomology of West Nile virus, you get pill-rolling tremor, dysdiaticokinesia, flexor dystonia mood flattening which eventually becomes something called flat affect no expression of mood at all people don't get really really happy they don't get really really pissed off and now they are diagnosed by observation with a disease that they don't have because they have a pathogen that we didn't test for again i'm not saying this is always the cause but i believe so much more in what god gave us than what man makes us that i believe the immune system rarely makes a mistake, it usually has a reason to be there.

48:12And if we would help find out what that reason is, we can maybe uncover the genesis of a lot of these conditions. Yes, ma 'am. What's that? Oh, you have the mic. Okay. I'll get you. You'll be in the next one. Okay. You can talk loud. Okay. She's going to yell and then I'll have you. Yeah.

48:30Yes. Can I talk about treating H. pylori without antibiotics? So helicobacter pylori is one of the leading causes of ulcers, right? It erodes something called the mucosal lining of the stomach. It also does it in the intestinal tract. And a lot of us have helicobacter pylori, but it proliferates in an environment where the stomach acid is too alkaline. And actually, the stomach acid being too alkaline is actually the leading cause of gastroesophageal reflux. You know, a lot of us get reflux, gastroesophageal reflux or heartburn, right? And we think that we should be taking proton pump inhibitors or antacids to actually raise the pH of the blood.

49:07Remember, the way the pH scale works is the lower it goes, you get more acidic. The higher it goes, you get more alkaline, more basic. There is a muscle at the top of the stomach called a cardiac sphincter. There's another one at the bottom of the stomach called a pyloric sphincter. And these two work in opposite, right? One opens, lets food in, closes. Then the other one opens and lets food out. And then it closes. And then this opens, lets food in, opens, lets food out. So this alternation between pyloric and cardiac sphincters is what allows, you know, contents to come down the esophagus, lay in the stomach for a while, and then pass into the intestine.

49:39As the acidity in the stomach starts to become more alkaline, that sphincter muscle relaxes, and acid spills out of the stomach into the esophagus. It also lays fertile ground for non-acidic bacteria like H. pylori, Helicobacter pylori. And so Helicobacter pylori erodes the mucosal wall of the stomach, and now the acid is laying right against unprotected stomach wall and it can create an ulcer. Eventually it can create a bleeding ulcer and eventually it can create a perforation. And so, um, you know, the, the, one of the first things I tell people that have acid reflux or H pylori is to restore the acid balance in the stomach.

50:19Take things like beta-ene hydrochloride, beta-ene HCL to actually lower your stomach acid and slam that sphincter muscles shut because by raising the pH, it will relax even further. You still have acid reflux. You just don't feel it because the acid is too alkaline. And now guess what happens? The stomach can't perform its job because the stomach's meant to be acidic. It has the pH of battery acid, and it's meant to kill bacteria. And what is H. pylori? It's a bacteria, just like all of our gut bacteria are bacteria. And so the whole role of the stomach is to kill bacteria. That's the reason why we have a stomach.

50:58That's the reason why the acid is so low. So by restoring proper acid balance, you can actually eliminate H. pylori. You're super welcome. Yes, ma 'am. Hi, Gary. I just want to dive in for you said there's normally one cost for autoimmune. Yes. And also the four causes, because I think there was one cost, but I'm not sure. Yeah. So you described me, I was always given importance to the business over my needs. So massive chronic stress, hardly any sleep for about 18 months and in the u.s i saw every specialist around autoimmune conditions because everything was under attack stomach brain lungs skin stomach ulcers everything yes eyes as well the the mouth was completely swollen yeah every one of them was a specific specialist there was a skin specialist a rheumatologist but i don't know if they were even talking to each other probably not and there wasn't a single cause so i went the entire time undiagnosed until i had i I was subconscious for a time.

51:53You were unconscious? Subconscious. Wow. I don't know if it was near-death experience, but I was completely subconscious. They couldn't give me the diagnosis. But the only way when I left the U.S. and I came here and I started healing, the stressors were gone. Yes. When you mentioned those four as well, so it's a two-part question. Yeah. Potential cause when the entire system is under attack, not one single one. And then the second part is I have a theory about glyphosates. So do I. Yeah. We can talk about glyphosate too. Because we were, I think I had to do it in the garden. We had to put glyphosates.

52:35It's just the expectation of all the neighbors that you cannot have a single weed. Yeah. And I just wonder if that was. Yeah. So glyphosate and paraquat are very, very dangerous chemicals. I mean, glyphosate has a causal link to non-Tchotchkes lymphoma and mesothelioma. and paraquat is now correlated to Parkinson's. Pretty soon it will be causal. The fascinating thing about these chemicals is paraquat, for example, which is made by ChemChina, is illegal in China. So it's made by ChemChina, but if you actually spray crops in China with paraquat, you can go to prison. It's a felony. So they export it to countries like the United Kingdom and the U.S., and then we spray our crops with it, and then we give broad immunity to chemical companies for known harm, not just indirect harm, but for known harm.

53:21In fact, in the US, I chair Bobby Kennedy's Maha Action Committee. And so I report directly to Bobby. And we are actually actively trying to stop chemical companies from broad shield liability from knowingly poisoning the populace. These are what we call forever chemicals. When you take them into the body, the body doesn't have an enzyme for them. It doesn't have a way to eliminate this waste. And so it lights the immune system up. in women you have a classic classic case of autoimmune i bet you did you have something called an an a titer speckled antibody titer do you remember there are a lot so many tests so so you know essentially what happens is you you run the nervous system down and the nervous system is what regulates the immune system so the autonomic nervous system what's regulating your breathing right and your heart rate and all of the things that you're not thinking about right now It's regulating your posture.

54:13It's keeping you upright in your chair. So the autonomic nervous system exists in two states. One is called the sympathetic state, which is a little misleading because that's the fight or flight state. And one is called the parasympathetic state. This is the rest and digest state. In the rest and digest state, this is when you're healthy, when you're healing, when you're repairing, when you're eliminating waste, when you're detoxifying and regenerating. When you're in a sympathetic state, because this is a fight or flight state, all of those systems stop. So people that are chronically overworked, they're type A, they have responsibilities at home, maybe you have a child you're caring for, a spouse you're caring for, and you have a career that's burgeoning and you're not getting a lot of sleep.

54:55What happens is the immune system gets trapped in the state of fight or flight. The immune system does not feel safe. The nervous system does not feel safe. We need to feel safe in our bodies before the immune system really begins to protect us. Things like regulating your sleep and wake cycle are the most critical things to restoring balance to this autonomic nervous system. Things like breath work, grounding, sunlight first thing in the morning, eating a whole food diet, and deepening your connections and relationships. When I start talking about connection as medicine and relationships as medicine and food as medicine, eyes roll back into people's heads.

55:36But if you actually look at the big data, This has actually been proven beyond any shadow of a doubt. If you took any blue zone in the world, there is no continuity between diets in the blue zone. If you went to Sardinia, you'd see the highest carbohydrate consumption in the world, one of the longest life expectancies. If you went to Singapore, you'd see the highest meat consumption per capita, one of the longest life expectancies. You go to the Mediterranean, high fatty fish, high oils, two liters of olive oil per person per week. two liters. If you told any cardiologist I was going to drink two liters of olive oil a week, they would kick you out of their office.

56:10And yet they're living long, healthy, happy lives. And then the French, pardon me if you're French, but the French screwed up the whole model

56:18Gary Brecka:because they're drinking wine, eating cheese, smoking cigarettes, and they're living to 100 years old. What was the continuity in the diets? It was not dogmatic dieting. The regions of the world we're not benefiting from carnivore keto paleo pescatarian vegan vegetarian raw food it was not dogmatic dieting it was the absence of processed foods in no blue zone in the world was there even an ounce of processed food in their diet that is the first thing the two non-negotiables in all of the blue zones in all of the longest life lives in the world our sense of community and purpose and mobility into later in life.

56:56We cannot replace those. So as you become more disconnected, your immune system becomes more trapped in a sympathetic state. As it becomes more trapped in a sympathetic state, it becomes increasingly more confused. And as it becomes more confused, it weakens. And as it weakens, it begins to lose its discernment between friendly and foreign tissue. And so when I said one thing causes everything, the initial thing was the actual overloaded stress response. You know, it was too much stress. You weren't mitigating stress. That's why I think that self-care should be non-negotiable. Like you should give the first 30 to 90 minutes of every day to yourself.

57:37When I woke up this morning, the first thing that I did was I found a local gym. I went, I did a cold plunge. I did a sauna. I did a 45 minute workout. I just, I gave, I fed my body. I gave the first 90 minutes of my day to me so I could give the rest of my day away. And I'm going to give the rest of my day to you and to, to everyone else. And so I would really, uh, I would be heavily focused on stress. Um, and also I would be heavily, heavily focused on my relationships and my sleep because we all know that sleep is important, but few of us know why sleep is so important. There are two phases of sleep that are absolutely critical to survival and thriving.

58:15And those are REM stage sleep and deep phase sleep. During deep phase sleep is the only time that a very special waste elimination pathway in your body is open. It's called the glymphatic pathway. We have lymph nodes and a lymphatic system in the body to eliminate waste. In the brain, we have a glymphatic system. The glymphatic system eliminates waste from the brain. By waste, I don't mean stool or urine. I mean cellular waste, inflammatory compounds. The brain actually swells during the day and it loses that swelling at night during deep phase and channels open in the brain and waste is eliminated.

58:51If you are not getting deep phases of sleep, you are not eliminating waste from the brain. People that chronically deprive themselves of sleep, Ronald Reagan, for example, used to brag about only five hours of sleep. Do you know what he died of? Alzheimer's. Margaret Thatcher used to brag about getting three to five hours of sleep. Do you know what she died of? Alzheimer's. And so not allowing our bodies the time to repair and regenerate through deep phases of sleep is critical to human optimization. The second is REM phase of sleep. REM phase of sleep is where we assemble memory. So if you watch my lecture, you're listening to me talk right now, and this is to become a learned memory.

59:30That learned memory will be assembled tonight during a REM phase of sleep when your prefrontal cortex and your hippocampus begin to communicate as they lose communication you're told you're losing your memory you are not losing your memory you are losing access to your memory the same thing happens in alzheimer's and dementia the memory does not leave the access to the memory leaves so i hope that answered your question yes ma 'am hi i scared you i'm sorry yeah it's supposed to be a positive one okay you've scared me a little because i've been consistently getting between three to five hours sleep the last two years which i don't wear as a badge of honor it's you know it's not a choice i can get to sleep relatively easily i take all the supplements that you recommend i've got quite a solid nighttime routine great great morning routine but three to five hours after going to sleep i'm waking up and that's me and you just mentioned there the memory I'll probably retain about 0.5 % of what you've just said today.

1:00:34So I've been taking lots of notes. But, you know, I'm listening to yourself and other experts talking about the trauma that it does to your brain when you have consistently the lack of sleep. I'm trying really hard not to stress about it because I know that that's going to make it even worse. So I'm trying to... Yeah, don't stress about it because that will make it worse. Have you done a genetic methylation test? I am going to do one. Okay, you very likely have a gene mutation called COMT, C-O-M-T. It stands for catecholomethyltransferase. So catecholamines build up two ways. Prior to sleep, they keep you in a wakened state when you lay down to go to sleep at night.

1:01:14They have you ruminating for a while and having a hard time falling asleep. Or you fall asleep and catecholamines wake you up at night. You'll notice that the types of thought patterns you have go straight to worst-case scenario. So if you imagine something in the middle of the night, it ends in a worst-case scenario. You can even sometimes catch yourself and go, I really took that one for a ride last night. I mean, I wake up, I wonder why I had this argument, my relationship's over, it's going to end in divorce. And then you get up the next day, everything's fine. And so catecholamines are the fight-or-flight neurotransmitters.

1:01:48And that gene mutation, it's critical to supplement for that genetic deficiency. You'll find that your sleep returns to normal. Yeah. So I'll take one more question so that we can. Yes, ma 'am. Yeah. Guys, by the way, thank you so much for giving me your time. I mean, it's really very humbling to see you guys paying attention like this. Thank you. Yeah.

1:02:15The catacombing. Yes. Because is there ways that you're obviously if you get a spike with the catacombing.

1:02:22Gary Brecka:Is there ways that what? Is there a way that you can take like a binder or some sort of activated charcoal to essentially it screws it out of the system? No. Because obviously if you've had this spike, do you just have to wait for it to... Yes. If you have a spike in catecholamines, you have to wait for your body to metabolize catecholamines. Catechol-O-methyltransferase, the gene COMT, which by the way is also on the Dutch test. Listen up females. And this is the most overlooked thing that OBGYNs will totally skip this gene mutation when they're looking at your estrogen metabolism. If you have that gene mutation, you're not sending estrogen down the E2 pathway, which means that estrogen is accumulating and the primary role of estrogen is to bind water in the interstitial tissue.

1:03:06It's to retain water, right? This is why so many women that do intermittent fasting and start an exercise program and start eating well, all of a sudden start to retain water. They think they're getting fat. They're not. They're getting water retensive. Nothing is more frustrating than starting an intermittent fasting program with your husband and he's down there sucking down pizza like his life depends on it and skipping workouts, and you're militant about what you're doing, and you're actually starting to retain water, right? And so the second thing is catecholamines are neurotransmitters that are demethylated.

1:03:37And methyl groups gets attached to them, and actually their activity is neutralized. And so it's critical that you supplement directly for that gene mutation. So when you do that gene test and you see that you have the COMT gene mutation, I will tell you exactly what nutrient to take and what dosage so that you can just restore that breakdown of catecholamines to normal. And it restores normalcy so you're not hyper aware, you're not hyper agitated, you don't get anxious. You certainly don't have anxiety, which is a very high rise in catecholamines. If they continue to rise beyond anxiety, you can have a panic attack.

1:04:12As colamines continue to rise, you will get paranoias. Those come from high excessive catecholamines. That's a severe, severe case. But lots of us, especially women, are walking around at like a six. When you should be walking around at a one or two, you should just feel calm inside your own body. When you don't, that is excess catecholamines. And they rob you of deep sleep and they bring anxiety into your present day. So I want to give you guys a chance to experience the ultimate human experience. All of those things are free. You can leave with all of them. You can get a genetic test on your way out.

1:04:49I'll stay and answer questions up here at this stage. But guys, thank you so much for your time. Thank you.